Ten Hacken NHT - Search Results

1

Bronchial Thermoplasty Induced Airway Smooth Muscle Reduction and Clinical Response in Severe Asthma. The TASMA Randomized Trial.

Goorsenberg AWM, d'Hooghe JNS, Srikanthan K, Ten Hacken NHT, Weersink EJM, Roelofs JJTH, Kemp SV, Bel EH, Shah PL, Annema JT, Bonta PI; TASMA research group. Goorsenberg AWM, et al. Among authors: ten hacken nht. Am J Respir Crit Care Med. 2021 Jan 15;203(2):175-184. doi: 10.1164/rccm.201911-2298OC. Am J Respir Crit Care Med. 2021. PMID: 32721210 Clinical Trial.

2

Exhaled nitric oxide is higher both at day and night in subjects with nocturnal asthma.

ten Hacken NH, van der Vaart H, van der Mark TW, Koëter GH, Postma DS. ten Hacken NH, et al. Am J Respir Crit Care Med. 1998 Sep;158(3):902-7. doi: 10.1164/ajrccm.158.3.9712021. Am J Respir Crit Care Med. 1998. PMID: 9731024

3

Increased peak expiratory flow variation in asthma: severe persistent increase but not nocturnal worsening of airway inflammation.

ten Hacken NH, Timens W, Smith M, Drok G, Kraan J, Postma DS. ten Hacken NH, et al. Eur Respir J. 1998 Sep;12(3):546-50. doi: 10.1183/09031936.98.12030546. Eur Respir J. 1998. PMID: 9762777 Free article. Clinical Trial.

4

Increased vascular expression of iNOS at day but not at night in asthmatic subjects with increased nocturnal airway obstruction.

ten Hacken NH, Postma DS, Drok G, Smith M, Kraan J, Timens W. ten Hacken NH, et al. Eur Respir J. 2000 Sep;16(3):445-51. doi: 10.1034/j.1399-3003.2000.016003445.x. Eur Respir J. 2000. PMID: 11028658 Free article.

5

First study of infliximab treatment in patients with chronic obstructive pulmonary disease.

van der Vaart H, Koëter GH, Postma DS, Kauffman HF, ten Hacken NH. van der Vaart H, et al. Am J Respir Crit Care Med. 2005 Aug 15;172(4):465-9. doi: 10.1164/rccm.200501-147OC. Epub 2005 Jun 3. Am J Respir Crit Care Med. 2005. PMID: 15937294 Clinical Trial.

6

Mast cell numbers in airway smooth muscle and PC20AMP in asthma and COPD.

Liesker JJ, Ten Hacken NH, Rutgers SR, Zeinstra-Smith M, Postma DS, Timens W. Liesker JJ, et al. Respir Med. 2007 May;101(5):882-7. doi: 10.1016/j.rmed.2006.10.001. Epub 2006 Nov 13. Respir Med. 2007. PMID: 17097865 Free article.

7

Ciclesonide improves measures of small airway involvement in asthma.

Cohen J, Douma WR, ten Hacken NH, Vonk JM, Oudkerk M, Postma DS. Cohen J, et al. Eur Respir J. 2008 Jun;31(6):1213-20. doi: 10.1183/09031936.00082407. Epub 2008 Feb 20. Eur Respir J. 2008. PMID: 18287130 Free article. Clinical Trial.

8

Physiology of the small airways: A gender difference?

Cohen J, Douma WR, Ten Hacken NH, Oudkerk M, Postma DS. Cohen J, et al. Respir Med. 2008 Sep;102(9):1264-71. doi: 10.1016/j.rmed.2008.04.007. Epub 2008 Jul 9. Respir Med. 2008. PMID: 18617383 Free article.

9

Reticular basement membrane in asthma and COPD: similar thickness, yet different composition.

Liesker JJ, Ten Hacken NH, Zeinstra-Smith M, Rutgers SR, Postma DS, Timens W. Liesker JJ, et al. Int J Chron Obstruct Pulmon Dis. 2009;4:127-35. doi: 10.2147/copd.s4639. Epub 2009 Apr 15. Int J Chron Obstruct Pulmon Dis. 2009. PMID: 19436691 Free PMC article.

10

Airway epithelial changes in smokers but not in ex-smokers with asthma.

Broekema M, ten Hacken NH, Volbeda F, Lodewijk ME, Hylkema MN, Postma DS, Timens W. Broekema M, et al. Am J Respir Crit Care Med. 2009 Dec 15;180(12):1170-8. doi: 10.1164/rccm.200906-0828OC. Epub 2009 Oct 1. Am J Respir Crit Care Med. 2009. PMID: 19797761

11

Airway eosinophilia in remission and progression of asthma: accumulation with a fast decline of FEV(1).

Broekema M, Volbeda F, Timens W, Dijkstra A, Lee NA, Lee JJ, Lodewijk ME, Postma DS, Hylkema MN, ten Hacken NH. Broekema M, et al. Respir Med. 2010 Sep;104(9):1254-62. doi: 10.1016/j.rmed.2010.03.030. Respir Med. 2010. PMID: 20434897 Free article.

12

Can AMP induce sputum eosinophils, even in subjects with complete asthma remission?

Volbeda F, ten Hacken NH, Lodewijk ME, Dijkstra A, Hylkema MN, Broekema M, Timens W, Postma DS. Volbeda F, et al. Respir Res. 2010 Aug 2;11(1):106. doi: 10.1186/1465-9921-11-106. Respir Res. 2010. PMID: 20678209 Free PMC article.

13

Persisting remodeling and less airway wall eosinophil activation in complete remission of asthma.

Broekema M, Timens W, Vonk JM, Volbeda F, Lodewijk ME, Hylkema MN, Ten Hacken NH, Postma DS. Broekema M, et al. Am J Respir Crit Care Med. 2011 Feb 1;183(3):310-6. doi: 10.1164/rccm.201003-0494OC. Epub 2010 Sep 2. Am J Respir Crit Care Med. 2011. PMID: 20813885

14

Consequences of physical inactivity in chronic obstructive pulmonary disease.

Hartman JE, Boezen HM, de Greef MH, Bossenbroek L, ten Hacken NH. Hartman JE, et al. Expert Rev Respir Med. 2010 Dec;4(6):735-45. doi: 10.1586/ers.10.76. Expert Rev Respir Med. 2010. PMID: 21128749 Review.

15

Smoking and nonsmoking asthma: differences in clinical outcome and pathogenesis.

Fattahi F, Hylkema MN, Melgert BN, Timens W, Postma DS, ten Hacken NH. Fattahi F, et al. Expert Rev Respir Med. 2011 Feb;5(1):93-105. doi: 10.1586/ers.10.85. Expert Rev Respir Med. 2011. PMID: 21348590 Review.

16

The minimal important difference for residual volume in patients with severe emphysema.

Hartman JE, Ten Hacken NH, Klooster K, Boezen HM, de Greef MH, Slebos DJ. Hartman JE, et al. Eur Respir J. 2012 Nov;40(5):1137-41. doi: 10.1183/09031936.00219111. Epub 2012 Mar 22. Eur Respir J. 2012. PMID: 22441742 Free article.

17

Clinical control of asthma associates with measures of airway inflammation.

Volbeda F, Broekema M, Lodewijk ME, Hylkema MN, Reddel HK, Timens W, Postma DS, ten Hacken NH. Volbeda F, et al. Thorax. 2013 Jan;68(1):19-24. doi: 10.1136/thoraxjnl-2012-201861. Epub 2012 Oct 6. Thorax. 2013. PMID: 23042704

18

Self-efficacy for physical activity and insight into its benefits are modifiable factors associated with physical activity in people with COPD: a mixed-methods study.

Hartman JE, ten Hacken NH, Boezen HM, de Greef MH. Hartman JE, et al. J Physiother. 2013 Jun;59(2):117-24. doi: 10.1016/S1836-9553(13)70164-4. J Physiother. 2013. PMID: 23663797 Free article.

19

Physical and psychosocial factors associated with physical activity in patients with chronic obstructive pulmonary disease.

Hartman JE, Boezen HM, de Greef MH, Ten Hacken NH. Hartman JE, et al. Arch Phys Med Rehabil. 2013 Dec;94(12):2396-2402.e7. doi: 10.1016/j.apmr.2013.06.029. Epub 2013 Jul 16. Arch Phys Med Rehabil. 2013. PMID: 23872081

20

Physical activity recommendations in patients with chronic obstructive pulmonary disease.

Hartman JE, Boezen HM, Zuidema MJ, de Greef MH, Ten Hacken NH. Hartman JE, et al. Respiration. 2014;88(2):92-100. doi: 10.1159/000360298. Epub 2014 May 14. Respiration. 2014. PMID: 24851826 Free article. Clinical Trial.

21

Effects of small airway dysfunction on the clinical expression of asthma: a focus on asthma symptoms and bronchial hyper-responsiveness.

van der Wiel E, Postma DS, van der Molen T, Schiphof-Godart L, Ten Hacken NH, van den Berge M. van der Wiel E, et al. Allergy. 2014 Dec;69(12):1681-8. doi: 10.1111/all.12510. Epub 2014 Oct 3. Allergy. 2014. PMID: 25123492

22

Long-term follow-up after bronchoscopic lung volume reduction treatment with coils in patients with severe emphysema.

Hartman JE, Klooster K, Gortzak K, ten Hacken NH, Slebos DJ. Hartman JE, et al. Respirology. 2015 Feb;20(2):319-26. doi: 10.1111/resp.12435. Epub 2014 Nov 23. Respirology. 2015. PMID: 25418910 Free PMC article. Clinical Trial.

23

Selecting the increment size for a maximal incremental cycle test in patients with COPD.

Hartman JE, Slebos DJ, Boezen HM, de Greef MH, Kerstjens HA, ten Hacken NH. Hartman JE, et al. Respirology. 2015 Feb;20(2):352-5. doi: 10.1111/resp.12451. Epub 2014 Dec 3. Respirology. 2015. PMID: 25470413

24

Frequent sputum production is associated with disturbed night's rest and impaired sleep quality in patients with COPD.

Hartman JE, Prinzen J, van Lummel RC, Ten Hacken NH. Hartman JE, et al. Sleep Breath. 2015 Dec;19(4):1125-33. doi: 10.1007/s11325-014-1111-9. Epub 2015 Mar 4. Sleep Breath. 2015. PMID: 25737300 Free PMC article.

25

[Bronchoscopic interventions in severe COPD: improvement of pulmonary function, exercise capacity and quality of life].

Klooster K, ten Hacken NH, Hartman JE, Kerstjens HA, Slebos DJ. Klooster K, et al. Ned Tijdschr Geneeskd. 2015;159:A8497. Ned Tijdschr Geneeskd. 2015. PMID: 25740189 Review. Dutch.

26

Treatment of emphysema using bronchoscopic lung volume reduction coil technology: an update on efficacy and safety.

Hartman JE, Klooster K, Ten Hacken NH, Slebos DJ. Hartman JE, et al. Ther Adv Respir Dis. 2015 Oct;9(5):251-9. doi: 10.1177/1753465815589904. Epub 2015 Jun 25. Ther Adv Respir Dis. 2015. PMID: 26113524 Free article. Review.

27

Determining the Role of Dynamic Hyperinflation in Patients with Severe Chronic Obstructive Pulmonary Disease.

Klooster K, ten Hacken NH, Hartman JE, Sciurba FC, Kerstjens HA, Slebos DJ. Klooster K, et al. Respiration. 2015;90(4):306-13. doi: 10.1159/000439056. Epub 2015 Sep 10. Respiration. 2015. PMID: 26352833 Free article. Clinical Trial.

28

The minimal important difference for the St George's Respiratory Questionnaire in patients with severe COPD.

Welling JB, Hartman JE, Ten Hacken NH, Klooster K, Slebos DJ. Welling JB, et al. Eur Respir J. 2015 Dec;46(6):1598-604. doi: 10.1183/13993003.00535-2015. Epub 2015 Oct 22. Eur Respir J. 2015. PMID: 26493797 Free article.

29

Endobronchial Valves for Emphysema without Interlobar Collateral Ventilation.

Klooster K, ten Hacken NH, Hartman JE, Kerstjens HA, van Rikxoort EM, Slebos DJ. Klooster K, et al. N Engl J Med. 2015 Dec 10;373(24):2325-35. doi: 10.1056/NEJMoa1507807. N Engl J Med. 2015. PMID: 26650153 Free article. Clinical Trial.

30

Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma.

Ierodiakonou D, Portelli MA, Postma DS, Koppelman GH, Gerritsen J, Ten Hacken NH, Timens W, Boezen HM, Vonk JM, Sayers I. Ierodiakonou D, et al. Eur Respir J. 2016 May;47(5):1568-71. doi: 10.1183/13993003.01571-2015. Epub 2016 Feb 11. Eur Respir J. 2016. PMID: 26869673 Free PMC article.

31

Improvement of physical activity after endobronchial valve treatment in emphysema patients.

Hartman JE, Klooster K, Slebos DJ, Ten Hacken NH. Hartman JE, et al. Respir Med. 2016 Aug;117:116-21. doi: 10.1016/j.rmed.2016.06.009. Epub 2016 Jun 9. Respir Med. 2016. PMID: 27492521 Free article. Clinical Trial.

32

One-Year Follow-Up after Endobronchial Valve Treatment in Patients with Emphysema without Collateral Ventilation Treated in the STELVIO Trial.

Klooster K, Hartman JE, Ten Hacken NH, Slebos DJ. Klooster K, et al. Respiration. 2017;93(2):112-121. doi: 10.1159/000453529. Epub 2016 Dec 15. Respiration. 2017. PMID: 27974713 Free PMC article.

33

Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids.

Kunz LI, Ten Hacken NH, Lapperre TS, Timens W, Kerstjens HA, van Schadewijk A, Vonk JM, Sont JK, Snoeck-Stroband JB, Postma DS, Sterk PJ, Hiemstra PS; GLUCOLD Study Group. Kunz LI, et al. Eur Respir J. 2017 Jan 3;49(1):1600839. doi: 10.1183/13993003.00839-2016. Print 2017 Jan. Eur Respir J. 2017. PMID: 28049170 Free article. Clinical Trial.

34

Improved Predictors of Survival after Endobronchial Valve Treatment in Patients with Severe Emphysema.

Klooster K, Hartman JE, Ten Hacken NHT, Slebos DJ. Klooster K, et al. Among authors: ten hacken nht. Am J Respir Crit Care Med. 2017 May 1;195(9):1272-1274. doi: 10.1164/rccm.201610-1993LE. Am J Respir Crit Care Med. 2017. PMID: 28459316 No abstract available.

35

The Safety and Feasibility of Re-treating Patients with Severe Emphysema with Endobronchial Coils: A Pilot Study.

Hartman JE, Klooster K, Ten Hacken NHT, Slebos DJ. Hartman JE, et al. Among authors: ten hacken nht. COPD. 2017 Jun;14(3):339-343. doi: 10.1080/15412555.2017.1318842. Epub 2017 May 12. COPD. 2017. PMID: 28498082

36

Pleural Adhesion Assessment as a Predictor for Pneumothorax after Endobronchial Valve Treatment.

van Geffen WH, Klooster K, Hartman JE, Ten Hacken NHT, Kerstjens HAM, Wolf RFE, Slebos DJ. van Geffen WH, et al. Among authors: ten hacken nht. Respiration. 2017;94(2):224-231. doi: 10.1159/000477258. Epub 2017 Jun 22. Respiration. 2017. PMID: 28637047 Free article.

37

Bronchial Provocation Testing Can Be Improved by Using Dry Powder Adenosine Instead of Nebulized Adenosine Monophosphate.

Lexmond AJ, Boudewijn IM, Hagedoorn P, Schokker S, Cox CA, Vonk JM, Ten Hacken NHT, Frijlink HW, Vroegop SJ, van den Berge M. Lexmond AJ, et al. Among authors: ten hacken nht. Am J Respir Crit Care Med. 2018 Feb 1;197(3):391-394. doi: 10.1164/rccm.201704-0715LE. Am J Respir Crit Care Med. 2018. PMID: 28650210 Clinical Trial. No abstract available.

38

Emerging understanding of the mechanism of action of Bronchial Thermoplasty in asthma.

d'Hooghe JNS, Ten Hacken NHT, Weersink EJM, Sterk PJ, Annema JT, Bonta PI. d'Hooghe JNS, et al. Among authors: ten hacken nht. Pharmacol Ther. 2018 Jan;181:101-107. doi: 10.1016/j.pharmthera.2017.07.015. Epub 2017 Jul 27. Pharmacol Ther. 2018. PMID: 28757156 Free article. Review.

39

A Multicenter Randomized Controlled Trial of Zephyr Endobronchial Valve Treatment in Heterogeneous Emphysema (TRANSFORM).

Kemp SV, Slebos DJ, Kirk A, Kornaszewska M, Carron K, Ek L, Broman G, Hillerdal G, Mal H, Pison C, Briault A, Downer N, Darwiche K, Rao J, Hübner RH, Ruwwe-Glosenkamp C, Trosini-Desert V, Eberhardt R, Herth FJ, Derom E, Malfait T, Shah PL, Garner JL, Ten Hacken NH, Fallouh H, Leroy S, Marquette CH; TRANSFORM Study Team *. Kemp SV, et al. Am J Respir Crit Care Med. 2017 Dec 15;196(12):1535-1543. doi: 10.1164/rccm.201707-1327OC. Am J Respir Crit Care Med. 2017. PMID: 28885054 Free article. Clinical Trial.

40

Minimal important difference of target lobar volume reduction after endobronchial valve treatment for emphysema.

Welling JBA, Hartman JE, van Rikxoort EM, Ten Hacken NHT, Kerstjens HAM, Klooster K, Slebos DJ. Welling JBA, et al. Among authors: ten hacken nht. Respirology. 2018 Mar;23(3):306-310. doi: 10.1111/resp.13178. Epub 2017 Sep 15. Respirology. 2018. PMID: 28913877 Clinical Trial.

41

Patient-specific goals significantly improve after endobronchial coil treatment in patients with severe emphysema.

Hartman JE, Klooster K, Ten Hacken NHT, Slebos DJ. Hartman JE, et al. Among authors: ten hacken nht. Clin Respir J. 2018 Jun;12(6):2157-2158. doi: 10.1111/crj.12781. Epub 2018 Mar 6. Clin Respir J. 2018. PMID: 29437296 Clinical Trial. No abstract available.

42

Cost-effectiveness of endobronchial valve treatment in patients with severe emphysema compared to standard medical care.

Hartman JE, Klooster K, Groen H, Ten Hacken NHT, Slebos DJ. Hartman JE, et al. Among authors: ten hacken nht. Respirology. 2018 Mar 25. doi: 10.1111/resp.13295. Online ahead of print. Respirology. 2018. PMID: 29575395 Free article.

43

Profiling of healthy and asthmatic airway smooth muscle cells following interleukin-1β treatment: a novel role for CCL20 in chronic mucus hypersecretion.

Faiz A, Weckmann M, Tasena H, Vermeulen CJ, Van den Berge M, Ten Hacken NHT, Halayko AJ, Ward JPT, Lee TH, Tjin G, Black JL, Haghi M, Xu CJ, King GG, Farah CS, Oliver BG, Heijink IH, Burgess JK. Faiz A, et al. Among authors: ten hacken nht. Eur Respir J. 2018 Aug 9;52(2):1800310. doi: 10.1183/13993003.00310-2018. Print 2018 Aug. Eur Respir J. 2018. PMID: 29946002 Free article.

44

Endobronchial Coils for Endoscopic Lung Volume Reduction: Best Practice Recommendations from an Expert Panel.

Slebos DJ, Ten Hacken NH, Hetzel M, Herth FJF, Shah PL. Slebos DJ, et al. Respiration. 2018;96(1):1-11. doi: 10.1159/000490193. Epub 2018 Jul 10. Respiration. 2018. PMID: 29991060 Free PMC article.

45

Cigarette Smoking Acutely Decreases Serum Levels of the Chronic Obstructive Pulmonary Disease Biomarker sRAGE.

Pouwels SD, Klont F, Kwiatkowski M, Wiersma VR, Faiz A, van den Berge M, Horvatovich P, Bischoff R, Ten Hacken NHT. Pouwels SD, et al. Among authors: ten hacken nht. Am J Respir Crit Care Med. 2018 Dec 1;198(11):1456-1458. doi: 10.1164/rccm.201807-1249LE. Am J Respir Crit Care Med. 2018. PMID: 30130135 No abstract available.

46

Airway smooth muscle reduction after bronchial thermoplasty in severe asthma correlates with FEV₁.

d'Hooghe JNS, Goorsenberg AWM, Ten Hacken NHT, Weersink EJM, Roelofs JJTH, Mauad T, Shah PL, Annema JT, Bonta PI; TASMA research group. d'Hooghe JNS, et al. Among authors: ten hacken nht. Clin Exp Allergy. 2019 Apr;49(4):541-544. doi: 10.1111/cea.13365. Epub 2019 Feb 20. Clin Exp Allergy. 2019. PMID: 30723963 No abstract available.

47

Confounding Factors Affecting sRAGE as a Biomarker for Chronic Obstructive Pulmonary Disease.

Pouwels SD, Klont F, Bischoff R, Ten Hacken NHT. Pouwels SD, et al. Among authors: ten hacken nht. Am J Respir Crit Care Med. 2019 Jul 1;200(1):114. doi: 10.1164/rccm.201902-0356LE. Am J Respir Crit Care Med. 2019. PMID: 30888832 Free PMC article. No abstract available.

48

Significant Differences in Body Plethysmography Measurements Between Hospitals in Patients Referred for Bronchoscopic Lung Volume Reduction.

Welling JBA, Hartman JE, Ten Hacken NHT, Augustijn SWS, Kerstjens HAM, Slebos DJ, Klooster K. Welling JBA, et al. Among authors: ten hacken nht. Lung. 2019 Oct;197(5):573-576. doi: 10.1007/s00408-019-00265-w. Epub 2019 Aug 31. Lung. 2019. PMID: 31473796

49

A New Oxygen Uptake Measurement Supporting Target Selection for Endobronchial Valve Treatment.

Welling JBA, Klooster K, Charbonnier JP, Van Rikxoort EM, Barends CRM, Kerstjens HAM, Ten Hacken NHT, Hartman JE, Slebos DJ. Welling JBA, et al. Among authors: ten hacken nht. Respiration. 2019;98(6):521-526. doi: 10.1159/000502310. Epub 2019 Sep 3. Respiration. 2019. PMID: 31480063 Free PMC article.

50

Laminin α4 contributes to airway remodeling and inflammation in asthma.

Prabhala P, Wright DB, Robbe P, Bitter C, Pera T, Ten Hacken NHT, van den Berge M, Timens W, Meurs H, Dekkers BGJ. Prabhala P, et al. Among authors: ten hacken nht. Am J Physiol Lung Cell Mol Physiol. 2019 Dec 1;317(6):L768-L777. doi: 10.1152/ajplung.00222.2019. Epub 2019 Sep 25. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 31553662 Free article.

51

Endobronchial Valve Treatment in Emphysema Patients with a Very Low DLCO.

van Dijk M, Hartman JE, Klooster K, Ten Hacken NHT, Kerstjens HAM, Slebos DJ. van Dijk M, et al. Among authors: ten hacken nht. Respiration. 2020;99(2):163-170. doi: 10.1159/000505428. Epub 2020 Jan 21. Respiration. 2020. PMID: 31962325 Free PMC article.

52

Effect of Zephyr Endobronchial Valves on Dyspnea, Activity Levels, and Quality of Life at One Year. Results from a Randomized Clinical Trial.

Dransfield MT, Garner JL, Bhatt SP, Slebos DJ, Klooster K, Sciurba FC, Shah PL, Marchetti NT, Sue RD, Wright S, Rivas-Perez H, Wiese TA, Wahidi MM, Goulart de Oliveira H, Armstrong B, Radhakrishnan S, Shargill NS, Criner GJ; LIBERATE Study Group:. Dransfield MT, et al. Ann Am Thorac Soc. 2020 Jul;17(7):829-838. doi: 10.1513/AnnalsATS.201909-666OC. Ann Am Thorac Soc. 2020. PMID: 32223724 Free PMC article. Clinical Trial.

53

Determining Static Hyperinflation in Patients with Severe Emphysema: Relation Between Lung Function Parameters and Patient-Related Outcomes.

de Weger WW, Klooster K, Ten Hacken NH, van Dijk M, Hartman JE, Slebos DJ. de Weger WW, et al. Lung. 2020 Aug;198(4):629-636. doi: 10.1007/s00408-020-00368-9. Epub 2020 Jun 28. Lung. 2020. PMID: 32596757 Free PMC article.

54

Change in Dynamic Hyperinflation After Bronchoscopic Lung Volume Reduction in Patients with Emphysema.

van Dijk M, Klooster K, Hartman JE, Ten Hacken NHT, Slebos DJ. van Dijk M, et al. Among authors: ten hacken nht. Lung. 2020 Oct;198(5):795-801. doi: 10.1007/s00408-020-00382-x. Epub 2020 Jul 24. Lung. 2020. PMID: 32710165 Free PMC article. Clinical Trial.

55

Patient Satisfaction and Attainment of Patient-Specific Goals after Endobronchial Valve Treatment.

Hartman JE, Klooster K, Ten Hacken NHT, van Dijk M, Slebos DJ. Hartman JE, et al. Among authors: ten hacken nht. Ann Am Thorac Soc. 2021 Jan;18(1):68-74. doi: 10.1513/AnnalsATS.202004-342OC. Ann Am Thorac Soc. 2021. PMID: 32881586

56

Metabolic differences between bronchial epithelium from healthy individuals and patients with asthma and the effect of bronchial thermoplasty.

Ravi A, Goorsenberg AWM, Dijkhuis A, Dierdorp BS, Dekker T, van Weeghel M, Sabogal Piñeros YS, Shah PL, Ten Hacken NHT, Annema JT, Sterk PJ, Vaz FM, Bonta PI, Lutter R. Ravi A, et al. Among authors: ten hacken nht. J Allergy Clin Immunol. 2021 Nov;148(5):1236-1248. doi: 10.1016/j.jaci.2020.12.653. Epub 2021 Feb 6. J Allergy Clin Immunol. 2021. PMID: 33556463 Free article. Clinical Trial.

57

Comparison of Multiple Diagnostic Tests to Measure Dynamic Hyperinflation in Patients with Severe Emphysema Treated with Endobronchial Coils.

van Dijk M, Hartman JE, Augustijn SWS, Ten Hacken NHT, Klooster K, Slebos DJ. van Dijk M, et al. Among authors: ten hacken nht. Lung. 2021 Apr;199(2):195-198. doi: 10.1007/s00408-021-00430-0. Epub 2021 Mar 9. Lung. 2021. PMID: 33687513 Free PMC article. Clinical Trial.

58

Identifying Responders and Exploring Mechanisms of Action of the Endobronchial Coil Treatment for Emphysema.

Hartman JE, Klooster K, Augustijn SWS, van Geffen WH, Garner JL, Shah PL, Ten Hacken NHT, Slebos DJ. Hartman JE, et al. Among authors: ten hacken nht. Respiration. 2021;100(5):443-451. doi: 10.1159/000514319. Epub 2021 Mar 19. Respiration. 2021. PMID: 33744899 Free PMC article.

59

Bronchoscopic Targeted Lung Denervation in Patients with Severe Asthma: Preliminary Findings.

Hartman JE, Srikanthan K, Caneja C, Ten Hacken NHT, Kerstjens HAM, Shah PL, Slebos DJ. Hartman JE, et al. Among authors: ten hacken nht. Respiration. 2022;101(2):184-189. doi: 10.1159/000518515. Epub 2021 Sep 1. Respiration. 2022. PMID: 34515243 Free PMC article.

60

Long-term follow-up after bronchoscopic lung volume reduction valve treatment for emphysema.

Hartman JE, Klooster K, Koster TD, Ten Hacken NHT, van Dijk M, Slebos DJ. Hartman JE, et al. Among authors: ten hacken nht. ERJ Open Res. 2022 Nov 21;8(4):00235-2022. doi: 10.1183/23120541.00235-2022. eCollection 2022 Oct. ERJ Open Res. 2022. PMID: 36415650 Free PMC article.

61

Airway Inflammation Before and After Bronchial Thermoplasty in Severe Asthma.

Wijsman PC, Goorsenberg AWM, Ravi A, d'Hooghe JNS, Dierdorp BS, Dekker T, van Schaik CCLM, Ten Hacken NHT, Shah PL, Weersink EJM, Bel EH, Annema JT, Lutter R, Bonta PI. Wijsman PC, et al. Among authors: ten hacken nht. J Asthma Allergy. 2022 Dec 16;15:1783-1794. doi: 10.2147/JAA.S383418. eCollection 2022. J Asthma Allergy. 2022. PMID: 36560975 Free PMC article.

62

Airway wall extracellular matrix changes induced by bronchial thermoplasty in severe asthma.

Wijsman PC, Goorsenberg AWM, Keijzer N, d'Hooghe JNS, Ten Hacken NHT, Shah PL, Weersink EJM, de Brito JM, de Souza Xavier Costa N, Mauad T, Nawijn MC, Vonk JM, Annema JT, Burgess JK, Bonta PI. Wijsman PC, et al. Among authors: ten hacken nht. J Allergy Clin Immunol. 2024 Feb;153(2):435-446.e4. doi: 10.1016/j.jaci.2023.09.035. Epub 2023 Oct 5. J Allergy Clin Immunol. 2024. PMID: 37805024 Free article.

63

Submucosa 1.0 x 0.1 mm in size is sufficient to count inflammatory cell numbers in human airway biopsy specimens.

ten Hacken NH, Aleva RM, Oosterhoff Y, Smith M, Kraan J, Postma DS, Timens W. ten Hacken NH, et al. Mod Pathol. 1998 Mar;11(3):292-4. Mod Pathol. 1998. PMID: 9521478

64

Elevated serum interferon-gamma in atopic asthma correlates with increased airways responsiveness and circadian peak expiratory flow variation.

ten Hacken NH, Oosterhoff Y, Kauffman HF, Guevarra L, Satoh T, Tollerud DJ, Postma DS. ten Hacken NH, et al. Eur Respir J. 1998 Feb;11(2):312-6. doi: 10.1183/09031936.98.11020312. Eur Respir J. 1998. PMID: 9551730 Free article.

65

Vascular adhesion molecules in nocturnal asthma: a possible role for VCAM-1 in ongoing airway wall inflammation.

ten Hacken NH, Postma DS, Bosma F, Drok G, Rutgers B, Kraan J, Timens W. ten Hacken NH, et al. Clin Exp Allergy. 1998 Dec;28(12):1518-25. doi: 10.1046/j.1365-2222.1998.00426.x. Clin Exp Allergy. 1998. PMID: 10024223

66

Borg scores before and after challenge with adenosine 5'-monophosphate and methacholine in subjects with COPD and asthma.

Rutgers SR, ten Hacken NH, Koeter GH, Postma DS. Rutgers SR, et al. Eur Respir J. 2000 Sep;16(3):486-90. doi: 10.1034/j.1399-3003.2000.016003486.x. Eur Respir J. 2000. PMID: 11028665 Free article.

67

Airway remodeling and long-term decline in lung function in asthma.

Ten Hacken NH, Postma DS, Timens W. Ten Hacken NH, et al. Curr Opin Pulm Med. 2003 Jan;9(1):9-14. doi: 10.1097/00063198-200301000-00002. Curr Opin Pulm Med. 2003. PMID: 12476078 Review.

68

Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers.

Willemse BW, ten Hacken NH, Rutgers B, Lesman-Leegte IG, Postma DS, Timens W. Willemse BW, et al. Eur Respir J. 2005 Nov;26(5):835-45. doi: 10.1183/09031936.05.00108904. Eur Respir J. 2005. PMID: 16264044 Free article. Clinical Trial.

69

Association of mast cells with lung function in chronic obstructive pulmonary disease.

Gosman MM, Postma DS, Vonk JM, Rutgers B, Lodewijk M, Smith M, Luinge MA, Ten Hacken NH, Timens W. Gosman MM, et al. Respir Res. 2008 Sep 10;9(1):64. doi: 10.1186/1465-9921-9-64. Respir Res. 2008. PMID: 18783610 Free PMC article.

70

Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial.

Lapperre TS, Snoeck-Stroband JB, Gosman MM, Jansen DF, van Schadewijk A, Thiadens HA, Vonk JM, Boezen HM, Ten Hacken NH, Sont JK, Rabe KF, Kerstjens HA, Hiemstra PS, Timens W, Postma DS, Sterk PJ; Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease Study Group. Lapperre TS, et al. Ann Intern Med. 2009 Oct 20;151(8):517-27. doi: 10.7326/0003-4819-151-8-200910200-00004. Ann Intern Med. 2009. PMID: 19841453 Clinical Trial.

71

Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD.

Budulac SE, Postma DS, Hiemstra PS, Kunz LI, Siedlinski M, Smit HA, Vonk JM, Rutgers B, Timens W, Boezen HM; Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease (GLUCOLD) study group. Budulac SE, et al. Respir Res. 2010 May 20;11(1):60. doi: 10.1186/1465-9921-11-60. Respir Res. 2010. PMID: 20487524 Free PMC article.

72

Small airway disease in asthma and COPD: clinical implications.

van den Berge M, Ten Hacken NHT, Cohen J, Douma WR, Postma DS. van den Berge M, et al. Among authors: ten hacken nht. Chest. 2011 Feb;139(2):412-423. doi: 10.1378/chest.10-1210. Chest. 2011. PMID: 21285055 Review.

73

A better response in exercise capacity after pulmonary rehabilitation in more severe COPD patients.

Altenburg WA, de Greef MH, ten Hacken NH, Wempe JB. Altenburg WA, et al. Respir Med. 2012 May;106(5):694-700. doi: 10.1016/j.rmed.2011.11.008. Epub 2011 Dec 6. Respir Med. 2012. PMID: 22154126 Free article.

74

Clinical and inflammatory determinants of bronchial hyperresponsiveness in COPD.

van den Berge M, Vonk JM, Gosman M, Lapperre TS, Snoeck-Stroband JB, Sterk PJ, Kunz LI, Hiemstra PS, Timens W, Ten Hacken NH, Kerstjens HA, Postma DS. van den Berge M, et al. Eur Respir J. 2012 Nov;40(5):1098-105. doi: 10.1183/09031936.00169711. Epub 2012 Apr 20. Eur Respir J. 2012. PMID: 22523354 Free article.

75

Daily physical activity after bronchoscopic lung volume reduction: a pilot study.

Hartman JE, Boezen HM, Heintzbergen S, de Greef MH, Klooster K, ten Hacken NH, Slebos DJ. Hartman JE, et al. Eur Respir J. 2012 Dec;40(6):1566-7. doi: 10.1183/09031936.00072112. Eur Respir J. 2012. PMID: 23204021 Free article. No abstract available.

76

Inhaled steroids modulate extracellular matrix composition in bronchial biopsies of COPD patients: a randomized, controlled trial.

Kunz LI, Strebus J, Budulac SE, Lapperre TS, Sterk PJ, Postma DS, Mauad T, Timens W, Hiemstra PS; GLUCOLD (Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease) Study Group. Kunz LI, et al. PLoS One. 2013 May 7;8(5):e63430. doi: 10.1371/journal.pone.0063430. Print 2013. PLoS One. 2013. PMID: 23667615 Free PMC article. Clinical Trial.

77

Less small airway dysfunction in asymptomatic bronchial hyperresponsiveness than in asthma.

Boudewijn IM, Telenga ED, van der Wiel E, van der Molen T, Schiphof L, Ten Hacken NH, Postma DS, van den Berge M. Boudewijn IM, et al. Allergy. 2013 Nov;68(11):1419-26. doi: 10.1111/all.12242. Epub 2013 Oct 12. Allergy. 2013. PMID: 24128343

78

Eosinophilic inflammation in subjects with mild-to-moderate asthma with and without obesity: disparity between sputum and biopsies.

van der Wiel E, Ten Hacken NH, van den Berge M, Timens W, Reddel HK, Postma DS. van der Wiel E, et al. Am J Respir Crit Care Med. 2014 May 15;189(10):1281-4. doi: 10.1164/rccm.201310-1841LE. Am J Respir Crit Care Med. 2014. PMID: 24832748 No abstract available.

79

Lung volume reduction coil treatment in chronic obstructive pulmonary disease patients with homogeneous emphysema: a prospective feasibility trial.

Klooster K, Ten Hacken NH, Franz I, Kerstjens HA, van Rikxoort EM, Slebos DJ. Klooster K, et al. Respiration. 2014;88(2):116-25. doi: 10.1159/000362522. Epub 2014 May 28. Respiration. 2014. PMID: 24902999 Free article. Clinical Trial.

80

Advanced glycation end products in the skin are enhanced in COPD.

Hoonhorst SJ, Lo Tam Loi AT, Hartman JE, Telenga ED, van den Berge M, Koenderman L, Lammers JW, Boezen HM, Postma DS, Ten Hacken NH. Hoonhorst SJ, et al. Metabolism. 2014 Sep;63(9):1149-56. doi: 10.1016/j.metabol.2014.06.006. Epub 2014 Jun 13. Metabolism. 2014. PMID: 25034386 Clinical Trial.

81

Small airway dysfunction in asymptomatic bronchial hyperresponsiveness and asthma.

Guan WJ, Zheng XY, Zheng JP, Boudewijn IM, Telenga ED, van der Wiel E, van der Molen T, Schiphof L, Ten Hacken NH, S Postma D, van den Berge M. Guan WJ, et al. Allergy. 2014 Sep;69(9):1258-9. doi: 10.1111/all.12425. Allergy. 2014. PMID: 25104269 No abstract available.

82

Short- and long-term effects of a physical activity counselling programme in COPD: a randomized controlled trial.

Altenburg WA, ten Hacken NH, Bossenbroek L, Kerstjens HA, de Greef MH, Wempe JB. Altenburg WA, et al. Respir Med. 2015 Jan;109(1):112-21. doi: 10.1016/j.rmed.2014.10.020. Epub 2014 Nov 22. Respir Med. 2015. PMID: 25499548 Free article. Clinical Trial.

83

Old dilemma: asthma with irreversible airway obstruction or COPD.

Fattahi F, Vonk JM, Bulkmans N, Fleischeuer R, Gouw A, Grünberg K, Mauad T, Popper H, Felipe-Silva A, Vrugt B, Wright JL, Yang HM, Kocks JW, Hylkema MN, Postma DS, Timens W, Ten Hacken NH. Fattahi F, et al. Virchows Arch. 2015 Nov;467(5):583-93. doi: 10.1007/s00428-015-1824-6. Epub 2015 Sep 14. Virchows Arch. 2015. PMID: 26369547 Free PMC article.

84

Prediction of Long-Term Benefits of Inhaled Steroids by Phenotypic Markers in Moderate-to-Severe COPD: A Randomized Controlled Trial.

Snoeck-Stroband JB, Lapperre TS, Sterk PJ, Hiemstra PS, Thiadens HA, Boezen HM, Ten Hacken NH, Kerstjens HA, Postma DS, Timens W, Sont JK; GLUCOLD Study Group. Snoeck-Stroband JB, et al. PLoS One. 2015 Dec 10;10(12):e0143793. doi: 10.1371/journal.pone.0143793. eCollection 2015. PLoS One. 2015. PMID: 26659582 Free PMC article. Clinical Trial.

85

Parametric response mapping on chest computed tomography associates with clinical and functional parameters in chronic obstructive pulmonary disease.

Pompe E, Galbán CJ, Ross BD, Koenderman L, Ten Hacken NH, Postma DS, van den Berge M, de Jong PA, Lammers JJ, Mohamed Hoesein FA. Pompe E, et al. Respir Med. 2017 Feb;123:48-55. doi: 10.1016/j.rmed.2016.11.021. Epub 2016 Nov 25. Respir Med. 2017. PMID: 28137496 Free PMC article.

86

Extrafine compared to non-extrafine particle inhaled corticosteroids in smokers and ex-smokers with asthma.

Cox CA, Boudewijn IM, Vroegop SJ, Schokker S, Lexmond AJ, Frijlink HW, Hagedoorn P, Vonk JM, Farenhorst MP, Ten Hacken NHT, Kerstjens HAM, Postma DS, van den Berge M. Cox CA, et al. Among authors: ten hacken nht. Respir Med. 2017 Sep;130:35-42. doi: 10.1016/j.rmed.2017.07.005. Epub 2017 Jul 8. Respir Med. 2017. PMID: 29206631 Free article. Clinical Trial.

87

Chartis Measurement of Collateral Ventilation: Conscious Sedation versus General Anesthesia - A Retrospective Comparison.

Welling JBA, Hartman JE, Ten Hacken NHT, Franz I, Charbonnier JP, van Rikxoort EM, Kerstjens HAM, Klooster K, Slebos DJ. Welling JBA, et al. Among authors: ten hacken nht. Respiration. 2018;96(5):480-487. doi: 10.1159/000490733. Epub 2018 Aug 16. Respiration. 2018. PMID: 30114707 Free PMC article.

88

Reply to Biswas: Acute and Chronic Effects of Cigarette Smoking on sRAGE.

Pouwels SD, Klont F, Kwiatkowski M, Wiersma VR, Faiz A, van den Berge M, Horvatovich P, Bischoff R, Ten Hacken NHT. Pouwels SD, et al. Among authors: ten hacken nht. Am J Respir Crit Care Med. 2019 Mar 15;199(6):806-807. doi: 10.1164/rccm.201812-2257LE. Am J Respir Crit Care Med. 2019. PMID: 30589564 Free PMC article. No abstract available.

89

Differential DNA methylation in bronchial biopsies between persistent asthma and asthma in remission.

Vermeulen CJ, Xu CJ, Vonk JM, Ten Hacken NHT, Timens W, Heijink IH, Nawijn MC, Boekhoudt J, van Oosterhout AJ, Affleck K, Weckmann M, Koppelman GH, van den Berge M. Vermeulen CJ, et al. Among authors: ten hacken nht. Eur Respir J. 2020 Feb 6;55(2):1901280. doi: 10.1183/13993003.01280-2019. Print 2020 Feb. Eur Respir J. 2020. PMID: 31699840 Free article.

90

Endobronchial valve therapy for severe emphysema: an overview of valve-related complications and its management.

Koster TD, Klooster K, Ten Hacken NHT, van Dijk M, Slebos DJ. Koster TD, et al. Among authors: ten hacken nht. Expert Rev Respir Med. 2020 Dec;14(12):1235-1247. doi: 10.1080/17476348.2020.1813571. Epub 2020 Aug 31. Expert Rev Respir Med. 2020. PMID: 32842819 Review.

91

Techniques in human airway inflammation: differences in plastic-embedded and snap-frozen sections for CD3, CD4, and CD8 immunostaining of bronchial biopsy specimens.

ten Hacken NH, Aleva RM, Rutgers B, Kraan J, van Goor H, Postma DS, Timens W. ten Hacken NH, et al. Mod Pathol. 1997 Oct;10(10):1043-6. Mod Pathol. 1997. PMID: 9346185

92

Are asthma and chronic obstructive pulmonary disease different diseases?--Con.

ten Hacken NH, Postma DS, Timens W. ten Hacken NH, et al. Monaldi Arch Chest Dis. 1999 Dec;54(6):551-8. Monaldi Arch Chest Dis. 1999. PMID: 10695329 Review. No abstract available.

93

The impact of smoking cessation on respiratory symptoms, lung function, airway hyperresponsiveness and inflammation.

Willemse BW, Postma DS, Timens W, ten Hacken NH. Willemse BW, et al. Eur Respir J. 2004 Mar;23(3):464-76. doi: 10.1183/09031936.04.00012704. Eur Respir J. 2004. PMID: 15065840 Free article. Review.

94

A disintegrin and metalloprotease 33 and chronic obstructive pulmonary disease pathophysiology.

Gosman MM, Boezen HM, van Diemen CC, Snoeck-Stroband JB, Lapperre TS, Hiemstra PS, Ten Hacken NH, Stolk J, Postma DS. Gosman MM, et al. Thorax. 2007 Mar;62(3):242-7. doi: 10.1136/thx.2006.060988. Epub 2006 Nov 7. Thorax. 2007. PMID: 17090574 Free PMC article.

95

Chronic bronchitis sub-phenotype within COPD: inflammation in sputum and biopsies.

Snoeck-Stroband JB, Lapperre TS, Gosman MM, Boezen HM, Timens W, ten Hacken NH, Sont JK, Sterk PJ, Hiemstra PS; Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease (GLUCOLD) Study Group. Snoeck-Stroband JB, et al. Eur Respir J. 2008 Jan;31(1):70-7. doi: 10.1183/09031936.00137006. Epub 2007 Sep 5. Eur Respir J. 2008. PMID: 17804442 Free article.

96

FVC to slow inspiratory vital capacity ratio: a potential marker for small airways obstruction.

Cohen J, Postma DS, Vink-Klooster K, van der Bij W, Verschuuren E, Ten Hacken NH, Koëter GH, Douma WR. Cohen J, et al. Chest. 2007 Oct;132(4):1198-203. doi: 10.1378/chest.06-2763. Epub 2007 Sep 21. Chest. 2007. PMID: 17890480

97

Localization and quantification of regional and segmental air trapping in asthma.

Cohen J, Douma WR, van Ooijen PM, Willems TP, Dicken V, Kuhnigk JM, ten Hacken NH, Postma DS, Oudkerk M. Cohen J, et al. J Comput Assist Tomogr. 2008 Jul-Aug;32(4):562-9. doi: 10.1097/RCT.0b013e31815f2bb0. J Comput Assist Tomogr. 2008. PMID: 18664844

98

Particle size matters: diagnostics and treatment of small airways involvement in asthma.

Cohen J, Postma DS, Douma WR, Vonk JM, De Boer AH, ten Hacken NH. Cohen J, et al. Eur Respir J. 2011 Mar;37(3):532-40. doi: 10.1183/09031936.00204109. Epub 2010 Jul 1. Eur Respir J. 2011. PMID: 20595155 Free article. Clinical Trial.

99

Atopy is a risk factor for respiratory symptoms in COPD patients: results from the EUROSCOP study.

Fattahi F, ten Hacken NH, Löfdahl CG, Hylkema MN, Timens W, Postma DS, Vonk JM. Fattahi F, et al. Respir Res. 2013 Jan 28;14(1):10. doi: 10.1186/1465-9921-14-10. Respir Res. 2013. PMID: 23356508 Free PMC article.

100

Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells.

Hoffmann RF, Zarrintan S, Brandenburg SM, Kol A, de Bruin HG, Jafari S, Dijk F, Kalicharan D, Kelders M, Gosker HR, Ten Hacken NH, van der Want JJ, van Oosterhout AJ, Heijink IH. Hoffmann RF, et al. Respir Res. 2013 Oct 2;14(1):97. doi: 10.1186/1465-9921-14-97. Respir Res. 2013. PMID: 24088173 Free PMC article.

101

Glucocorticoids induce the production of the chemoattractant CCL20 in airway epithelium.

Zijlstra GJ, Fattahi F, Rozeveld D, Jonker MR, Kliphuis NM, van den Berge M, Hylkema MN, ten Hacken NH, van Oosterhout AJ, Heijink IH. Zijlstra GJ, et al. Eur Respir J. 2014 Aug;44(2):361-70. doi: 10.1183/09031936.00209513. Epub 2014 Mar 13. Eur Respir J. 2014. PMID: 24627531 Free article.

102

Increased activation of blood neutrophils after cigarette smoking in young individuals susceptible to COPD.

Hoonhorst SJ, Timens W, Koenderman L, Lo Tam Loi AT, Lammers JW, Boezen HM, van Oosterhout AJ, Postma DS, Ten Hacken NH. Hoonhorst SJ, et al. Respir Res. 2014 Oct 10;15(1):121. doi: 10.1186/s12931-014-0121-2. Respir Res. 2014. PMID: 25301367 Free PMC article.

103

Budesonide and fluticasone propionate differentially affect the airway epithelial barrier.

Heijink IH, Jonker MR, de Vries M, van Oosterhout AJ, Telenga E, Ten Hacken NH, Postma DS, van den Berge M. Heijink IH, et al. Respir Res. 2016 Jan 6;17:2. doi: 10.1186/s12931-015-0318-z. Respir Res. 2016. PMID: 26739349 Free PMC article.

104

Advanced glycation endproducts and their receptor in different body compartments in COPD.

Hoonhorst SJ, Lo Tam Loi AT, Pouwels SD, Faiz A, Telenga ED, van den Berge M, Koenderman L, Lammers JW, Boezen HM, van Oosterhout AJ, Lodewijk ME, Timens W, Postma DS, Ten Hacken NH. Hoonhorst SJ, et al. Respir Res. 2016 Apr 26;17:46. doi: 10.1186/s12931-016-0363-2. Respir Res. 2016. PMID: 27117828 Free PMC article. Clinical Trial.

105

Atopy and Inhaled Corticosteroid Use Associate with Fewer IL-17+ Cells in Asthmatic Airways.

Fattahi F, Brandsma CA, Lodewijk M, Reinders-Luinge M, Postma DS, Timens W, Hylkema MN, Ten Hacken NH. Fattahi F, et al. PLoS One. 2016 Aug 23;11(8):e0161433. doi: 10.1371/journal.pone.0161433. eCollection 2016. PLoS One. 2016. PMID: 27552197 Free PMC article.

106

Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids.

Kunz LIZ, Ten Hacken NH, Lapperre TS, Timens W, Kerstjens HAM, van Schadewijk A, Vonk JM, Sont JK, Snoeck-Stroband JB, Postma DS, Sterk PJ, Hiemstra PS; GLUCOLD Study Group. Kunz LIZ, et al. Eur Respir J. 2017 Jun 15;49(6):1700848. doi: 10.1183/13993003.00848-2017. Print 2017 Jun. Eur Respir J. 2017. PMID: 28619964 Free article. No abstract available.

107

Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression.

Boudewijn IM, Faiz A, Steiling K, van der Wiel E, Telenga ED, Hoonhorst SJM, Ten Hacken NHT, Brandsma CA, Kerstjens HAM, Timens W, Heijink IH, Jonker MR, de Bruin HG, Sebastiaan Vroegop J, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Spira A, Lenburg ME, Guryev V, Postma DS, van den Berge M. Boudewijn IM, et al. Among authors: ten hacken nht. Respir Res. 2017 Dec 21;18(1):213. doi: 10.1186/s12931-017-0696-5. Respir Res. 2017. PMID: 29268739 Free PMC article. Clinical Trial.

108

AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers.

Faiz A, van den Berge M, Vermeulen CJ, Ten Hacken NHT, Guryev V, Pouwels SD. Faiz A, et al. Among authors: ten hacken nht. Respir Res. 2019 Apr 10;20(1):70. doi: 10.1186/s12931-019-1038-6. Respir Res. 2019. PMID: 30971245 Free PMC article.

109

Techniques in human airway inflammation: quantity and morphology of bronchial biopsy specimens taken by forceps of three sizes.

Aleva RM, Kraan J, Smith M, ten Hacken NH, Postma DS, Timens W. Aleva RM, et al. Chest. 1998 Jan;113(1):182-5. doi: 10.1378/chest.113.1.182. Chest. 1998. PMID: 9440588

110

Ongoing airway inflammation in patients with COPD who do not currently smoke.

Rutgers SR, Postma DS, ten Hacken NH, Kauffman HF, van Der Mark TW, Koëter GH, Timens W. Rutgers SR, et al. Thorax. 2000 Jan;55(1):12-8. doi: 10.1136/thorax.55.1.12. Thorax. 2000. PMID: 10607796 Free PMC article.

111

Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers.

Willemse BW, ten Hacken NH, Rutgers B, Postma DS, Timens W. Willemse BW, et al. Respir Res. 2005 Apr 25;6(1):38. doi: 10.1186/1465-9921-6-38. Respir Res. 2005. PMID: 15850494 Free PMC article. Clinical Trial.

112

Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells.

Zijlstra GJ, Ten Hacken NH, Hoffmann RF, van Oosterhout AJ, Heijink IH. Zijlstra GJ, et al. Eur Respir J. 2012 Feb;39(2):439-45. doi: 10.1183/09031936.00017911. Epub 2011 Aug 4. Eur Respir J. 2012. PMID: 21828034 Free article.

113

Treatment of the bronchial tree from beginning to end: targeting small airway inflammation in asthma.

van den Berge M, ten Hacken NH, van der Wiel E, Postma DS. van den Berge M, et al. Allergy. 2013 Jan;68(1):16-26. doi: 10.1111/all.12062. Allergy. 2013. PMID: 23210509 Review.

114

Small-airways dysfunction associates with respiratory symptoms and clinical features of asthma: a systematic review.

van der Wiel E, ten Hacken NH, Postma DS, van den Berge M. van der Wiel E, et al. J Allergy Clin Immunol. 2013 Mar;131(3):646-57. doi: 10.1016/j.jaci.2012.12.1567. Epub 2013 Feb 4. J Allergy Clin Immunol. 2013. PMID: 23380222 Review.

115

Functional and psychological variables both affect daily physical activity in COPD: a structural equations model.

Altenburg WA, Bossenbroek L, de Greef MH, Kerstjens HA, ten Hacken NH, Wempe JB. Altenburg WA, et al. Respir Med. 2013 Nov;107(11):1740-7. doi: 10.1016/j.rmed.2013.06.002. Epub 2013 Jun 28. Respir Med. 2013. PMID: 23810269 Free article. Clinical Trial.

116

Lower corticosteroid skin blanching response is associated with severe COPD.

Hoonhorst SJ, ten Hacken NH, Lo Tam Loi AT, Koenderman L, Lammers JW, Telenga ED, Boezen HM, van den Berge M, Postma DS. Hoonhorst SJ, et al. PLoS One. 2014 Mar 12;9(3):e91788. doi: 10.1371/journal.pone.0091788. eCollection 2014. PLoS One. 2014. PMID: 24622644 Free PMC article. Clinical Trial.

117

Airway wall thickness on HRCT scans decreases with age and increases with smoking.

Telenga ED, Oudkerk M, van Ooijen PM, Vliegenthart R, Ten Hacken NH, Postma DS, van den Berge M. Telenga ED, et al. BMC Pulm Med. 2017 Feb 1;17(1):27. doi: 10.1186/s12890-017-0363-0. BMC Pulm Med. 2017. PMID: 28143620 Free PMC article.

118

Cognitive performance in patients with COPD.

Liesker JJ, Postma DS, Beukema RJ, ten Hacken NH, van der Molen T, Riemersma RA, van Zomeren EH, Kerstjens HA. Liesker JJ, et al. Respir Med. 2004 Apr;98(4):351-6. doi: 10.1016/j.rmed.2003.11.004. Respir Med. 2004. PMID: 15072176 Free article.

119

Expression of ADAMs ("a disintegrin and metalloprotease") in the human lung.

Dijkstra A, Postma DS, Noordhoek JA, Lodewijk ME, Kauffman HF, ten Hacken NH, Timens W. Dijkstra A, et al. Virchows Arch. 2009 Apr;454(4):441-9. doi: 10.1007/s00428-009-0748-4. Epub 2009 Mar 3. Virchows Arch. 2009. PMID: 19255780 Free article.

120

The lung volume reduction coil for the treatment of emphysema: a new therapy in development.

Klooster K, Ten Hacken NH, Slebos DJ. Klooster K, et al. Expert Rev Med Devices. 2014 Sep;11(5):481-9. doi: 10.1586/17434440.2014.929490. Epub 2014 Aug 4. Expert Rev Med Devices. 2014. PMID: 25087905 Review.

121

Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release.

Heijink IH, Pouwels SD, Leijendekker C, de Bruin HG, Zijlstra GJ, van der Vaart H, ten Hacken NH, van Oosterhout AJ, Nawijn MC, van der Toorn M. Heijink IH, et al. Am J Respir Cell Mol Biol. 2015 May;52(5):554-62. doi: 10.1165/rcmb.2013-0505OC. Am J Respir Cell Mol Biol. 2015. PMID: 25192219 Clinical Trial.

122

Targeting the small airways with dry powder adenosine: a challenging concept.

van der Wiel E, Lexmond AJ, van den Berge M, Postma DS, Hagedoorn P, Frijlink HW, Farenhorst MP, de Boer AH, Ten Hacken NHT. van der Wiel E, et al. Among authors: ten hacken nht. Eur Clin Respir J. 2017 Sep 6;4(1):1369328. doi: 10.1080/20018525.2017.1369328. eCollection 2017. Eur Clin Respir J. 2017. PMID: 29057065 Free PMC article.

123

Gene expression profiling of bronchial brushes is associated with the level of emphysema measured by computed tomography-based parametric response mapping.

Rathnayake SNH, Hoesein FAAM, Galban CJ, Ten Hacken NHT, Oliver BGG, van den Berge M, Faiz A. Rathnayake SNH, et al. Among authors: ten hacken nht. Am J Physiol Lung Cell Mol Physiol. 2020 Jun 1;318(6):L1222-L1228. doi: 10.1152/ajplung.00051.2020. Epub 2020 Apr 22. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32320267 Free PMC article.

124

Gene signatures from scRNA-seq accurately quantify mast cells in biopsies in asthma.

Jiang J, Faiz A, Berg M, Carpaij OA, Vermeulen CJ, Brouwer S, Hesse L, Teichmann SA, Ten Hacken NHT, Timens W, van den Berge M, Nawijn MC. Jiang J, et al. Among authors: ten hacken nht. Clin Exp Allergy. 2020 Dec;50(12):1428-1431. doi: 10.1111/cea.13732. Epub 2020 Sep 23. Clin Exp Allergy. 2020. PMID: 32935368 Free PMC article. No abstract available.

125

Relation between duration of smoking cessation and bronchial inflammation in COPD.

Lapperre TS, Postma DS, Gosman MM, Snoeck-Stroband JB, ten Hacken NH, Hiemstra PS, Timens W, Sterk PJ, Mauad T. Lapperre TS, et al. Thorax. 2006 Feb;61(2):115-21. doi: 10.1136/thx.2005.040519. Epub 2005 Jul 29. Thorax. 2006. PMID: 16055612 Free PMC article.

126

Small airways in asthma: their independent contribution to the severity of hyperresponsiveness.

Telenga ED, van den Berge M, Ten Hacken NH, Riemersma RA, van der Molen T, Postma DS. Telenga ED, et al. Eur Respir J. 2013 Mar;41(3):752-4. doi: 10.1183/09031936.00170912. Eur Respir J. 2013. PMID: 23456934 Free article. No abstract available.

127

Associations of AMP and adenosine induced dyspnea sensation to large and small airways dysfunction in asthma.

Cox CA, Boudewijn IM, Vroegop SJ, Schokker S, Lexmond AJ, Frijlink HW, Hagedoorn P, Vonk JM, Farenhorst MP, Ten Hacken NHT, Kerstjens HAM, van den Berge M. Cox CA, et al. Among authors: ten hacken nht. BMC Pulm Med. 2019 Jan 28;19(1):23. doi: 10.1186/s12890-019-0783-0. BMC Pulm Med. 2019. PMID: 30691429 Free PMC article.

128

The effects of lung volume reduction treatment on diffusing capacity and gas exchange.

van Dijk M, Klooster K, Ten Hacken NHT, Sciurba F, Kerstjens HAM, Slebos DJ. van Dijk M, et al. Among authors: ten hacken nht. Eur Respir Rev. 2020 Oct 28;29(158):190171. doi: 10.1183/16000617.0171-2019. Print 2020 Dec 31. Eur Respir Rev. 2020. PMID: 33115787 Free PMC article. Review.

129

Neutrophilic Asthma Is Associated With Smoking, High Numbers of IRF5+, and Low Numbers of IL10+ Macrophages.

Turan N, van der Veen TA, Draijer C, Fattahi F, Ten Hacken NH, Timens W, van Oosterhout AJ, van den Berge M, Melgert BN. Turan N, et al. Front Allergy. 2021 Jun 21;2:676930. doi: 10.3389/falgy.2021.676930. eCollection 2021. Front Allergy. 2021. PMID: 35387061 Free PMC article.

130

Peripheral blood T lymphocytes from asthmatic patients are primed for enhanced expression of interleukin (IL)-4 and IL-5 mRNA: associations with lung function and serum IgE.

Borger P, Ten Hacken NH, Vellenga E, Kauffman HF, Postma DS. Borger P, et al. Clin Exp Allergy. 1999 Jun;29(6):772-9. doi: 10.1046/j.1365-2222.1999.00478.x. Clin Exp Allergy. 1999. PMID: 10336593

131

Home treatment of COPD exacerbations.

Postma DS, Ten Hacken NH, Kerstjens HA, Koëter GH. Postma DS, et al. Thorax. 1999 Aug;54 Suppl 2(Suppl 2):S8-13. doi: 10.1136/thx.54.2008.s8. Thorax. 1999. PMID: 10451685 Free PMC article. Review. No abstract available.

132

[Nitric oxide and asthma].

ten Hacken NH, Timens W, van der Mark TW, Nijkamp FP, Postma DS, Folkerts G. ten Hacken NH, et al. Ned Tijdschr Geneeskd. 1999 Jul 31;143(31):1606-11. Ned Tijdschr Geneeskd. 1999. PMID: 10488372 Review. Dutch.

133

A systematic review of the effects of bronchodilators on exercise capacity in patients with COPD.

Liesker JJ, Wijkstra PJ, Ten Hacken NH, Koëter GH, Postma DS, Kerstjens HA. Liesker JJ, et al. Chest. 2002 Feb;121(2):597-608. doi: 10.1378/chest.121.2.597. Chest. 2002. PMID: 11834677 Review.

134

Development, validity and responsiveness of the Clinical COPD Questionnaire.

van der Molen T, Willemse BW, Schokker S, ten Hacken NH, Postma DS, Juniper EF. van der Molen T, et al. Health Qual Life Outcomes. 2003 Apr 28;1:13. doi: 10.1186/1477-7525-1-13. Health Qual Life Outcomes. 2003. PMID: 12773199 Free PMC article.

135

Acute effects of cigarette smoke on inflammation and oxidative stress: a review.

van der Vaart H, Postma DS, Timens W, ten Hacken NH. van der Vaart H, et al. Thorax. 2004 Aug;59(8):713-21. doi: 10.1136/thx.2003.012468. Thorax. 2004. PMID: 15282395 Free PMC article. Review.

136

Smoking cessation improves both direct and indirect airway hyperresponsiveness in COPD.

Willemse BW, ten Hacken NH, Rutgers B, Lesman-Leegte IG, Timens W, Postma DS. Willemse BW, et al. Eur Respir J. 2004 Sep;24(3):391-6. doi: 10.1183/09031936.04.00117603. Eur Respir J. 2004. PMID: 15358697 Free article.

137

Acute effects of cigarette smoking on inflammation in healthy intermittent smokers.

van der Vaart H, Postma DS, Timens W, Hylkema MN, Willemse BW, Boezen HM, Vonk JM, de Reus DM, Kauffman HF, ten Hacken NH. van der Vaart H, et al. Respir Res. 2005 Mar 1;6(1):22. doi: 10.1186/1465-9921-6-22. Respir Res. 2005. PMID: 15740629 Free PMC article. Clinical Trial.

138

Lung function decline in asthma: association with inhaled corticosteroids, smoking and sex.

Dijkstra A, Vonk JM, Jongepier H, Koppelman GH, Schouten JP, ten Hacken NH, Timens W, Postma DS. Dijkstra A, et al. Thorax. 2006 Feb;61(2):105-10. doi: 10.1136/thx.2004.039271. Epub 2005 Nov 24. Thorax. 2006. PMID: 16308336 Free PMC article.

139

[Efficacy of combined treatment with corticosteroids and beta2 agonists in adults with asthma].

ten Hacken NH, Kerstjens HA, Postma DS. ten Hacken NH, et al. Ned Tijdschr Geneeskd. 2006 Apr 22;150(16):892-7. Ned Tijdschr Geneeskd. 2006. PMID: 16686088 Review. Dutch.

140

[Improved exercise tolerance can be achieved in chronic obstructive pulmonary disease (COPD) by means of non-pharmacological treatment].

Wijkstra PJ, Wempe JB, van der Bij W, Klinkenberg T, ten Hacken NH, Köeter GH. Wijkstra PJ, et al. Ned Tijdschr Geneeskd. 2006 Jun 3;150(22):1213-7. Ned Tijdschr Geneeskd. 2006. PMID: 16796170 Dutch.

141

[Pedometers for monitoring and improvement of the level of physical activity].

ten Hacken NH, de Greef MH. ten Hacken NH, et al. Ned Tijdschr Geneeskd. 2008 Jan 26;152(4):193-7. Ned Tijdschr Geneeskd. 2008. PMID: 18320943 Review. Dutch.

142

Inhaled corticosteroids and long-acting beta-agonists in adult asthma: a winning combination in all?

Postma DS, Kerstjens HA, ten Hacken NH. Postma DS, et al. Naunyn Schmiedebergs Arch Pharmacol. 2008 Aug;378(2):203-15. doi: 10.1007/s00210-008-0302-y. Epub 2008 May 24. Naunyn Schmiedebergs Arch Pharmacol. 2008. PMID: 18500509 Free PMC article. Retracted. Review.

143

Inhaled corticosteroids in chronic obstructive pulmonary disease: a review.

Telenga ED, Kerstjens HA, Postma DS, Ten Hacken NH, van den Berge M. Telenga ED, et al. Expert Opin Pharmacother. 2010 Feb;11(3):405-21. doi: 10.1517/14656560903510628. Expert Opin Pharmacother. 2010. PMID: 20102305 Review.

144

Determinants of overweight and obesity in lung transplant recipients.

Bossenbroek L, den Ouden ME, de Greef MH, Douma WR, Ten Hacken NH, van der Bij W. Bossenbroek L, et al. Respiration. 2011;82(1):28-35. doi: 10.1159/000322833. Epub 2011 Jan 5. Respiration. 2011. PMID: 21212650 Free article.

145

Validation of the DynaPort MiniMod during sleep: a pilot study.

Bossenbroek L, Kosse N, Ten Hacken N, Gordijn M, Van der Hoeven J, De Greef M. Bossenbroek L, et al. Percept Mot Skills. 2010 Dec;111(3):936-46. doi: 10.2466/03.15.PMS.111.6.936-946. Percept Mot Skills. 2010. PMID: 21319630

146

Characterization of protocadherin-1 expression in primary bronchial epithelial cells: association with epithelial cell differentiation.

Koning H, Sayers I, Stewart CE, de Jong D, Ten Hacken NH, Postma DS, van Oosterhout AJ, Nawijn MC, Koppelman GH. Koning H, et al. FASEB J. 2012 Jan;26(1):439-48. doi: 10.1096/fj.11-185207. Epub 2011 Oct 7. FASEB J. 2012. PMID: 21982948

147

Toll-like receptor (TLR2 and TLR4) polymorphisms and chronic obstructive pulmonary disease.

Budulac SE, Boezen HM, Hiemstra PS, Lapperre TS, Vonk JM, Timens W, Postma DS; GLUCOLD study group. Budulac SE, et al. PLoS One. 2012;7(8):e43124. doi: 10.1371/journal.pone.0043124. Epub 2012 Aug 28. PLoS One. 2012. PMID: 22952638 Free PMC article.

148

Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: from specific disease phenotyping towards novel therapy. Protocol of a cross-sectional study.

Lo Tam Loi AT, Hoonhorst SJ, Franciosi L, Bischoff R, Hoffmann RF, Heijink I, van Oosterhout AJ, Boezen HM, Timens W, Postma DS, Lammers JW, Koenderman L, Ten Hacken NH. Lo Tam Loi AT, et al. BMJ Open. 2013 Feb 1;3(2):e002178. doi: 10.1136/bmjopen-2012-002178. Print 2013. BMJ Open. 2013. PMID: 23377993 Free PMC article.

149

Expression of vascular remodelling markers in relation to bradykinin receptors in asthma and COPD.

Ricciardolo FL, Sabatini F, Sorbello V, Benedetto S, Defilippi I, Petecchia L, Usai C, Gnemmi I, Balbi B, De Rose V, Ten Hacken NH, Postma DS, Timens W, Di Stefano A. Ricciardolo FL, et al. Thorax. 2013 Sep;68(9):803-11. doi: 10.1136/thoraxjnl-2012-202741. Epub 2013 Jun 5. Thorax. 2013. PMID: 23739138

150

Inflammation and corticosteroid responsiveness in ex-, current- and never-smoking asthmatics.

Telenga ED, Kerstjens HA, Ten Hacken NH, Postma DS, van den Berge M. Telenga ED, et al. BMC Pulm Med. 2013 Sep 22;13:58. doi: 10.1186/1471-2466-13-58. BMC Pulm Med. 2013. PMID: 24053453 Free PMC article.

151

Steroid resistance in COPD? Overlap and differential anti-inflammatory effects in smokers and ex-smokers.

Hoonhorst SJ, ten Hacken NH, Vonk JM, Timens W, Hiemstra PS, Lapperre TS, Sterk PJ, Postma DS. Hoonhorst SJ, et al. PLoS One. 2014 Feb 5;9(2):e87443. doi: 10.1371/journal.pone.0087443. eCollection 2014. PLoS One. 2014. PMID: 24505290 Free PMC article. Clinical Trial.

152

Asthma and chronic obstructive pulmonary disease: similarities and differences.

Postma DS, Reddel HK, ten Hacken NH, van den Berge M. Postma DS, et al. Clin Chest Med. 2014 Mar;35(1):143-56. doi: 10.1016/j.ccm.2013.09.010. Epub 2013 Dec 12. Clin Chest Med. 2014. PMID: 24507842 Review.

153

Susceptibility to COPD: differential proteomic profiling after acute smoking.

Franciosi L, Postma DS, van den Berge M, Govorukhina N, Horvatovich PL, Fusetti F, Poolman B, Lodewijk ME, Timens W, Bischoff R, ten Hacken NH. Franciosi L, et al. PLoS One. 2014 Jul 18;9(7):e102037. doi: 10.1371/journal.pone.0102037. eCollection 2014. PLoS One. 2014. PMID: 25036363 Free PMC article.

154

Development of a tool to recognize small airways dysfunction in asthma (SADT).

Schiphof-Godart L, van der Wiel E, Ten Hacken NH, van den Berge M, Postma DS, van der Molen T. Schiphof-Godart L, et al. Health Qual Life Outcomes. 2014 Nov 22;12:155. doi: 10.1186/s12955-014-0155-7. Health Qual Life Outcomes. 2014. PMID: 25416552 Free PMC article.

155

Changes in the endurance shuttle walk test in COPD patients with chronic respiratory failure after pulmonary rehabilitation: the minimal important difference obtained with anchor- and distribution-based method.

Altenburg WA, Duiverman ML, Ten Hacken NH, Kerstjens HA, de Greef MH, Wijkstra PJ, Wempe JB. Altenburg WA, et al. Respir Res. 2015 Feb 19;16(1):27. doi: 10.1186/s12931-015-0182-x. Respir Res. 2015. PMID: 25849109 Free PMC article. Clinical Trial.

156

Effects of ageing and smoking on pulmonary computed tomography scans using parametric response mapping.

Boudewijn IM, Postma DS, Telenga ED, Ten Hacken NH, Timens W, Oudkerk M, Ross BD, Galbán CJ, van den Berge M. Boudewijn IM, et al. Eur Respir J. 2015 Oct;46(4):1193-6. doi: 10.1183/09031936.00009415. Epub 2015 Jun 25. Eur Respir J. 2015. PMID: 26113678 Free PMC article. No abstract available.

157

Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD.

Ngkelo A, Hoffmann RF, Durham AL, Marwick JA, Brandenburg SM, de Bruin HG, Jonker MR, Rossios C, Tsitsiou E, Caramori G, Contoli M, Casolari P, Monaco F, Andò F, Speciale G, Kilty I, Chung KF, Papi A, Lindsay MA, Ten Hacken NH, van den Berge M, Timens W, Barnes PJ, van Oosterhout AJ, Adcock IM, Kirkham PA, Heijink IH. Ngkelo A, et al. Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1112-23. doi: 10.1152/ajplung.00077.2015. Epub 2015 Aug 28. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 26320152 Free PMC article.

158

Quantitative antibody-free LC-MS/MS analysis of sTRAIL in sputum and saliva at the sub-ng/mL level.

Wilffert D, Donzelli R, Asselman A, Hermans J, Govorukhina N, Ten Hacken NH, Quax WJ, van de Merbel NC, Bischoff R. Wilffert D, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 1;1032:205-210. doi: 10.1016/j.jchromb.2016.04.041. Epub 2016 Apr 26. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27250581

159

Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma.

Nieuwenhuis MA, Siedlinski M, van den Berge M, Granell R, Li X, Niens M, van der Vlies P, Altmüller J, Nürnberg P, Kerkhof M, van Schayck OC, Riemersma RA, van der Molen T, de Monchy JG, Bossé Y, Sandford A, Bruijnzeel-Koomen CA, Gerth van Wijk R, Ten Hacken NH, Timens W, Boezen HM, Henderson J, Kabesch M, Vonk JM, Postma DS, Koppelman GH. Nieuwenhuis MA, et al. Allergy. 2016 Dec;71(12):1712-1720. doi: 10.1111/all.12990. Epub 2016 Aug 22. Allergy. 2016. PMID: 27439200 Free PMC article.

160

Human asthma is characterized by more IRF5+ M1 and CD206+ M2 macrophages and less IL-10+ M2-like macrophages around airways compared with healthy airways.

Draijer C, Boorsma CE, Robbe P, Timens W, Hylkema MN, Ten Hacken NH, van den Berge M, Postma DS, Melgert BN. Draijer C, et al. J Allergy Clin Immunol. 2017 Jul;140(1):280-283.e3. doi: 10.1016/j.jaci.2016.11.020. Epub 2016 Dec 19. J Allergy Clin Immunol. 2017. PMID: 28007476 No abstract available.

161

Assuring Consistent Performance of an Insulin-Like Growth Factor 1 MALDImmunoassay by Monitoring Measurement Quality Indicators.

Klont F, Ten Hacken NHT, Horvatovich P, Bakker SJL, Bischoff R. Klont F, et al. Among authors: ten hacken nht. Anal Chem. 2017 Jun 6;89(11):6188-6195. doi: 10.1021/acs.analchem.7b01125. Epub 2017 May 10. Anal Chem. 2017. PMID: 28467045 Free PMC article.

162

CT-Based Local Distribution Metric Improves Characterization of COPD.

Hoff BA, Pompe E, Galbán S, Postma DS, Lammers JJ, Ten Hacken NHT, Koenderman L, Johnson TD, Verleden SE, de Jong PA, Mohamed Hoesein FAA, van den Berge M, Ross BD, Galbán CJ. Hoff BA, et al. Among authors: ten hacken nht. Sci Rep. 2017 Jun 7;7(1):2999. doi: 10.1038/s41598-017-02871-1. Sci Rep. 2017. PMID: 28592874 Free PMC article.

163

Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice.

Pouwels SD, Faiz A, den Boef LE, Gras R, van den Berge M, Boezen HM, Korstanje R, Ten Hacken NHT, van Oosterhout AJM, Heijink IH, Nawijn MC. Pouwels SD, et al. Among authors: ten hacken nht. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L559-L580. doi: 10.1152/ajplung.00466.2016. Epub 2017 Jun 8. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28596295 Free article.

164

Mesenchymal Stromal Cells to Regenerate Emphysema: On the Horizon?

Kruk DMLW, Heijink IH, Slebos DJ, Timens W, Ten Hacken NH. Kruk DMLW, et al. Respiration. 2018;96(2):148-158. doi: 10.1159/000488149. Epub 2018 May 2. Respiration. 2018. PMID: 29719298 Free PMC article. Review.

165

Affimers as an Alternative to Antibodies in an Affinity LC-MS Assay for Quantification of the Soluble Receptor of Advanced Glycation End-Products (sRAGE) in Human Serum.

Klont F, Hadderingh M, Horvatovich P, Ten Hacken NHT, Bischoff R. Klont F, et al. Among authors: ten hacken nht. J Proteome Res. 2018 Aug 3;17(8):2892-2899. doi: 10.1021/acs.jproteome.8b00414. Epub 2018 Jul 26. J Proteome Res. 2018. PMID: 30005571 Free PMC article.

166

MiR-31-5p: A shared regulator of chronic mucus hypersecretion in asthma and chronic obstructive pulmonary disease.

Tasena H, Boudewijn IM, Faiz A, Timens W, Hylkema MN, Berg M, Ten Hacken NHT, Brandsma CA, Heijink IH, van den Berge M. Tasena H, et al. Among authors: ten hacken nht. Allergy. 2020 Mar;75(3):703-706. doi: 10.1111/all.14060. Epub 2019 Oct 23. Allergy. 2020. PMID: 31545509 No abstract available.

167

Mitochondrial dysfunction increases pro-inflammatory cytokine production and impairs repair and corticosteroid responsiveness in lung epithelium.

Hoffmann RF, Jonker MR, Brandenburg SM, de Bruin HG, Ten Hacken NHT, van Oosterhout AJM, Heijink IH. Hoffmann RF, et al. Among authors: ten hacken nht. Sci Rep. 2019 Oct 21;9(1):15047. doi: 10.1038/s41598-019-51517-x. Sci Rep. 2019. PMID: 31636329 Free PMC article.

168

Predicted values for the forced expiratory flow adjusted for forced vital capacity, a descriptive study.

Cox CA, Vonk JM, Kerstjens HAM, van den Berge M, Ten Hacken NHT. Cox CA, et al. Among authors: ten hacken nht. ERJ Open Res. 2020 Dec 14;6(4):00426-2020. doi: 10.1183/23120541.00426-2020. eCollection 2020 Oct. ERJ Open Res. 2020. PMID: 33344626 Free PMC article.

169

Abnormalities in reparative function of lung-derived mesenchymal stromal cells in emphysema.

Kruk DMLW, Wisman M, Bruin HG, Lodewijk ME, Hof DJ, Borghuis T, Daamen WF, van Kuppevelt TH, Timens W, Burgess JK, Ten Hacken NHT, Heijink IH. Kruk DMLW, et al. Among authors: ten hacken nht. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L832-L844. doi: 10.1152/ajplung.00147.2020. Epub 2021 Mar 3. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33656381 Free article.

170

Plasma sRAGE levels strongly associate with centrilobular emphysema assessed by HRCT scans.

Klont F, Horvatovich P, Bowler RP, van Rikxoort E, Charbonnier JP, Kwiatkowski M, Lynch DA, Humphries S, Bischoff R, Ten Hacken NHT, Pouwels SD. Klont F, et al. Among authors: ten hacken nht. Respir Res. 2022 Jan 24;23(1):15. doi: 10.1186/s12931-022-01934-w. Respir Res. 2022. PMID: 35073932 Free PMC article.

171

L-Arginine is not the limiting factor for nitric oxide synthesis by human alveolar macrophages in vitro.

Muijsers RB, ten Hacken NH, Van Ark I, Folkerts G, Nijkamp FP, Postma DS. Muijsers RB, et al. Eur Respir J. 2001 Oct;18(4):667-71. doi: 10.1183/09031936.01.00101301. Eur Respir J. 2001. PMID: 11716172 Free article.

172

A different analysis applied to a mathematical model on output of exhaled nitric oxide.

Rottier BL, Cohen J, van der Mark TW, Douma WR, Duiverman EJ, ten Hacken NH. Rottier BL, et al. J Appl Physiol (1985). 2005 Jul;99(1):378-9; author reply 379-80. doi: 10.1152/japplphysiol.00163.2005. J Appl Physiol (1985). 2005. PMID: 16036910 Free article. No abstract available.

173

Third-line chemotherapy for small cell lung cancer.

de Jong WK, ten Hacken NH, Groen HJ. de Jong WK, et al. Lung Cancer. 2006 Jun;52(3):339-42. doi: 10.1016/j.lungcan.2006.02.005. Epub 2006 Mar 24. Lung Cancer. 2006. PMID: 16564112

174

Limiting factors of exercise performance 1 year after lung transplantation.

Reinsma GD, ten Hacken NH, Grevink RG, van der Bij W, Koëter GH, van Weert E. Reinsma GD, et al. J Heart Lung Transplant. 2006 Nov;25(11):1310-6. doi: 10.1016/j.healun.2006.08.008. J Heart Lung Transplant. 2006. PMID: 17097494 Free article.

175

Treatment of bronchiectasis in adults.

ten Hacken NH, Wijkstra PJ, Kerstjens HA. ten Hacken NH, et al. BMJ. 2007 Nov 24;335(7629):1089-93. doi: 10.1136/bmj.39384.657118.80. BMJ. 2007. PMID: 18033931 Free PMC article. Review. No abstract available.

176

Enhancement of daily physical activity increases physical fitness of outclinic COPD patients: results of an exercise counseling program.

Hospes G, Bossenbroek L, Ten Hacken NH, van Hengel P, de Greef MH. Hospes G, et al. Patient Educ Couns. 2009 May;75(2):274-8. doi: 10.1016/j.pec.2008.10.005. Epub 2008 Nov 25. Patient Educ Couns. 2009. PMID: 19036552 Clinical Trial.

177

Cross-sectional assessment of daily physical activity in chronic obstructive pulmonary disease lung transplant patients.

Bossenbroek L, ten Hacken NH, van der Bij W, Verschuuren EA, Koëter GH, de Greef MH. Bossenbroek L, et al. J Heart Lung Transplant. 2009 Feb;28(2):149-55. doi: 10.1016/j.healun.2008.11.905. J Heart Lung Transplant. 2009. PMID: 19201340

178

Physical inactivity and obesity: relation to asthma and chronic obstructive pulmonary disease?

ten Hacken NH. ten Hacken NH. Proc Am Thorac Soc. 2009 Dec;6(8):663-7. doi: 10.1513/pats.200907-070DP. Proc Am Thorac Soc. 2009. PMID: 20008872 Review.

179

Randomised controlled trial: Uplifting results of tiotropium in moderate COPD (GOLD stage 2).

Kerstjens HA, Ten Hacken NH. Kerstjens HA, et al. Evid Based Med. 2010 Apr;15(2):44-5. doi: 10.1136/ebm1037. Evid Based Med. 2010. PMID: 20436117 No abstract available.

180

Bronchiectasis.

ten Hacken NH, van der Molen T. ten Hacken NH, et al. BMJ. 2010 Jul 14;341:c2766. doi: 10.1136/bmj.c2766. BMJ. 2010. PMID: 20630967 No abstract available.

181

More alternative activation of macrophages in lungs of asthmatic patients.

Melgert BN, ten Hacken NH, Rutgers B, Timens W, Postma DS, Hylkema MN. Melgert BN, et al. J Allergy Clin Immunol. 2011 Mar;127(3):831-3. doi: 10.1016/j.jaci.2010.10.045. Epub 2010 Dec 17. J Allergy Clin Immunol. 2011. PMID: 21167569 No abstract available.

182

Daily physical activity in patients with chronic obstructive pulmonary disease: a systematic review.

Bossenbroek L, de Greef MH, Wempe JB, Krijnen WP, Ten Hacken NH. Bossenbroek L, et al. COPD. 2011 Aug;8(4):306-19. doi: 10.3109/15412555.2011.578601. Epub 2011 Jul 5. COPD. 2011. PMID: 21728804 Review.

183

Bronchiectasis.

Ten Hacken NH, Kerstjens HA. Ten Hacken NH, et al. BMJ Clin Evid. 2011 Aug 16;2011:1507. BMJ Clin Evid. 2011. PMID: 21846412 Free PMC article. Review.

184

Morphological measurements in computed tomography correlate with airflow obstruction in chronic obstructive pulmonary disease: systematic review and meta-analysis.

Xie X, de Jong PA, Oudkerk M, Wang Y, Ten Hacken NH, Miao J, Zhang G, de Bock GH, Vliegenthart R. Xie X, et al. Eur Radiol. 2012 Oct;22(10):2085-93. doi: 10.1007/s00330-012-2480-8. Epub 2012 Jun 15. Eur Radiol. 2012. PMID: 22699870 Free PMC article. Review.

185

TGF-β1 polymorphisms and asthma severity, airway inflammation, and remodeling.

Ierodiakonou D, Postma DS, Koppelman GH, Gerritsen J, ten Hacken NH, Timens W, Boezen HM, Vonk JM. Ierodiakonou D, et al. J Allergy Clin Immunol. 2013 Feb;131(2):582-5. doi: 10.1016/j.jaci.2012.08.013. Epub 2012 Oct 27. J Allergy Clin Immunol. 2013. PMID: 23111237 No abstract available.

186

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences.

Martinez FO, Helming L, Milde R, Varin A, Melgert BN, Draijer C, Thomas B, Fabbri M, Crawshaw A, Ho LP, Ten Hacken NH, Cobos Jiménez V, Kootstra NA, Hamann J, Greaves DR, Locati M, Mantovani A, Gordon S. Martinez FO, et al. Blood. 2013 Feb 28;121(9):e57-69. doi: 10.1182/blood-2012-06-436212. Epub 2013 Jan 4. Blood. 2013. PMID: 23293084 Free article.

187

Authors’ response to Persson C: primary lysis/necrosis of eosinophils and clinical control of asthma.

Fattahi F, Volbeda F, Broekema M, Lodewijk ME, Hylkema MN, Reddel HK, Timens W, Postma DS, ten Hacken NH. Fattahi F, et al. Thorax. 2013 Mar;68(3):295-6. doi: 10.1136/thoraxjnl-2012-203023. Thorax. 2013. PMID: 23527403 No abstract available.

188

Adenosine dry powder inhalation for bronchial challenge testing, part 1: inhaler and formulation development and in vitro performance testing.

Lexmond AJ, Hagedoorn P, van der Wiel E, Ten Hacken NH, Frijlink HW, de Boer AH. Lexmond AJ, et al. Eur J Pharm Biopharm. 2014 Jan;86(1):105-14. doi: 10.1016/j.ejpb.2013.06.027. Epub 2013 Oct 17. Eur J Pharm Biopharm. 2014. PMID: 24140941

189

DAMPs activating innate and adaptive immune responses in COPD.

Pouwels SD, Heijink IH, ten Hacken NH, Vandenabeele P, Krysko DV, Nawijn MC, van Oosterhout AJ. Pouwels SD, et al. Mucosal Immunol. 2014 Mar;7(2):215-26. doi: 10.1038/mi.2013.77. Epub 2013 Oct 23. Mucosal Immunol. 2014. PMID: 24150257 Free article. Review.

190

Profiling over 1500 lipids in induced lung sputum and the implications in studying lung diseases.

t'Kindt R, Telenga ED, Jorge L, Van Oosterhout AJ, Sandra P, Ten Hacken NH, Sandra K. t'Kindt R, et al. Anal Chem. 2015;87(9):4957-64. doi: 10.1021/acs.analchem.5b00732. Epub 2015 Apr 24. Anal Chem. 2015. PMID: 25884268

191

[Two sisters with lung emphysema].

Piscaer I, Franssen FM, Ten Hacken NH, Wouters EF, Janssen R. Piscaer I, et al. Ned Tijdschr Geneeskd. 2016;160:D497. Ned Tijdschr Geneeskd. 2016. PMID: 27879179 Dutch.

192

Proteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients.

Loi ALT, Hoonhorst S, van Aalst C, Langereis J, Kamp V, Sluis-Eising S, Ten Hacken N, Lammers JW, Koenderman L. Loi ALT, et al. Respir Res. 2017 May 22;18(1):100. doi: 10.1186/s12931-017-0586-x. Respir Res. 2017. PMID: 28532454 Free PMC article. Clinical Trial.

193

Small airway imaging phenotypes in biomass- and tobacco smoke-exposed patients with COPD.

Fernandes L, Gulati N, Fernandes Y, Mesquita AM, Sardessai M, Lammers JJ, Mohamed Hoesein FA, Ten Hacken NHT, van den Berge M, Galbán CJ, Siddiqui S. Fernandes L, et al. Among authors: ten hacken nht. ERJ Open Res. 2017 Apr 12;3(2):00124-2016. doi: 10.1183/23120541.00124-2016. eCollection 2017 Apr. ERJ Open Res. 2017. PMID: 28828380 Free PMC article.

194

Free Urinary Desmosine and Isodesmosine as COPD Biomarkers: The Relevance of Confounding Factors.

Ongay S, Sikma M, Horvatovich P, Hermans J, Miller BE, Ten Hacken NHT, Bischoff R. Ongay S, et al. Among authors: ten hacken nht. Chronic Obstr Pulm Dis. 2016 Mar 1;3(2):560-569. doi: 10.15326/jcopdf.3.2.2015.0159. Chronic Obstr Pulm Dis. 2016. PMID: 28848880 Free PMC article.

195

Impact of acute exposure to cigarette smoke on airway gene expression.

Billatos E, Faiz A, Gesthalter Y, LeClerc A, Alekseyev YO, Xiao X, Liu G, Ten Hacken NHT, Heijink IH, Timens W, Brandsma CA, Postma DS, van den Berge M, Spira A, Lenburg ME. Billatos E, et al. Among authors: ten hacken nht. Physiol Genomics. 2018 Sep 1;50(9):705-713. doi: 10.1152/physiolgenomics.00092.2017. Epub 2018 Jun 22. Physiol Genomics. 2018. PMID: 29932825 Free PMC article.

196

Quantification of the soluble Receptor of Advanced Glycation End-Products (sRAGE) by LC-MS after enrichment by strong cation exchange (SCX) solid-phase extraction (SPE) at the protein level.

Klont F, Joosten MR, Ten Hacken NHT, Horvatovich P, Bischoff R. Klont F, et al. Among authors: ten hacken nht. Anal Chim Acta. 2018 Dec 28;1043:45-51. doi: 10.1016/j.aca.2018.09.050. Epub 2018 Sep 29. Anal Chim Acta. 2018. PMID: 30392668 Free article.

197

Cigarette smoking prior to blood sampling acutely affects serum levels of the chronic obstructive pulmonary disease biomarker surfactant protein D.

Klont F, Horvatovich P, Ten Hacken NHT, Bischoff R. Klont F, et al. Among authors: ten hacken nht. Clin Chem Lab Med. 2020 Jul 28;58(8):e138-e141. doi: 10.1515/cclm-2019-1246. Clin Chem Lab Med. 2020. PMID: 32145054 Free article. No abstract available.

198

Cholinergic neuroplasticity in asthma driven by TrkB signaling.

Dragunas G, Woest ME, Nijboer S, Bos ST, van Asselt J, de Groot AP, Vohlídalová E, Vermeulen CJ, Ditz B, Vonk JM, Koppelman GH, van den Berge M, Ten Hacken NHT, Timens W, Munhoz CD, Prakash YS, Gosens R, Kistemaker LEM. Dragunas G, et al. Among authors: ten hacken nht. FASEB J. 2020 Jun;34(6):7703-7717. doi: 10.1096/fj.202000170R. Epub 2020 Apr 11. FASEB J. 2020. PMID: 32277855 Free PMC article.

199

Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways.

Aliee H, Massip F, Qi C, Stella de Biase M, van Nijnatten J, Kersten ETG, Kermani NZ, Khuder B, Vonk JM, Vermeulen RCH; U-BIOPRED study group; Cambridge Lung Cancer Early Detection Programme; INER-Ciencias Mexican Lung Program; Neighbors M, Tew GW, Grimbaldeston MA, Ten Hacken NHT, Hu S, Guo Y, Zhang X, Sun K, Hiemstra PS, Ponder BA, Mäkelä MJ, Malmström K, Rintoul RC, Reyfman PA, Theis FJ, Brandsma CA, Adcock IM, Timens W, Xu CJ, van den Berge M, Schwarz RF, Koppelman GH, Nawijn MC, Faiz A. Aliee H, et al. Among authors: ten hacken nht. Allergy. 2022 Feb;77(2):690-694. doi: 10.1111/all.15152. Epub 2021 Nov 3. Allergy. 2022. PMID: 34698405 Free PMC article. No abstract available.

200

Smoking induces shifts in cellular composition and transcriptome within the bronchial mucus barrier.

Rathnayake SNH, Ditz B, van Nijnatten J, Sadaf T, Hansbro PM, Brandsma CA, Timens W, van Schadewijk A, Hiemstra PS, Ten Hacken NHT, Oliver B, Kerstjens HAM, van den Berge M, Faiz A. Rathnayake SNH, et al. Among authors: ten hacken nht. Respirology. 2023 Feb;28(2):132-142. doi: 10.1111/resp.14401. Epub 2022 Nov 22. Respirology. 2023. PMID: 36414410 Free PMC article.

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