U54 HD090258/HD/NICHD NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2018	2
2019	4
2020	5
2021	1
2022	1
2023	0

1

Gaedigk A. Gaedigk A. Clin Pharmacol Ther. 2019 Aug;106(2):265-270. doi: 10.1002/cpt.1511. Clin Pharmacol Ther. 2019. PMID: 31355458 Free PMC article. No abstract available.

2

The Impact of Age and Genetics on Naltrexone Biotransformation.

Stancil SL, Nolte W, Pearce RE, Staggs VS, Leeder JS. Stancil SL, et al. Drug Metab Dispos. 2022 Feb;50(2):168-173. doi: 10.1124/dmd.121.000646. Epub 2021 Nov 2. Drug Metab Dispos. 2022. PMID: 34728519

3

Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy.

Brown JT, Bishop JR, Sangkuhl K, Nurmi EL, Mueller DJ, Dinh JC, Gaedigk A, Klein TE, Caudle KE, McCracken JT, de Leon J, Leeder JS. Brown JT, et al. Clin Pharmacol Ther. 2019 Jul;106(1):94-102. doi: 10.1002/cpt.1409. Epub 2019 Apr 13. Clin Pharmacol Ther. 2019. PMID: 30801677 Free PMC article. Review.

4

Ten Years' Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics.

Gaedigk A, Dinh JC, Jeong H, Prasad B, Leeder JS. Gaedigk A, et al. J Pers Med. 2018 Apr 17;8(2):15. doi: 10.3390/jpm8020015. J Pers Med. 2018. PMID: 29673183 Free PMC article. Review.

5

Ontogeny Related Changes in the Pediatric Liver Metabolome.

Wilson CM, Li Q, Gaedigk R, Bi C, de Wildt SN, Leeder JS, Fridley BL. Wilson CM, et al. Front Pediatr. 2020 Sep 29;8:549. doi: 10.3389/fped.2020.00549. eCollection 2020. Front Pediatr. 2020. PMID: 33117761 Free PMC article.

6

A Call for Clear and Consistent Communications Regarding the Role of Pharmacogenetics in Antidepressant Pharmacotherapy.

Hicks JK, Bishop JR, Gammal RS, Sangkuhl K, Bousman CA, Leeder JS, Llerena A, Mueller DJ, Ramsey LB, Scott SA, Skaar TC, Caudle KE, Klein TE, Gaedigk A. Hicks JK, et al. Clin Pharmacol Ther. 2020 Jan;107(1):50-52. doi: 10.1002/cpt.1661. Epub 2019 Oct 30. Clin Pharmacol Ther. 2020. PMID: 31664715 Free PMC article. No abstract available.

7

Alternative Splicing of the SLCO1B1 Gene: An Exploratory Analysis of Isoform Diversity in Pediatric Liver.

van Groen BD, Bi C, Gaedigk R, Staggs VS, Tibboel D, de Wildt SN, Leeder JS. van Groen BD, et al. Clin Transl Sci. 2020 May;13(3):509-519. doi: 10.1111/cts.12733. Epub 2020 Jan 9. Clin Transl Sci. 2020. PMID: 31917523 Free PMC article.

8

GMSimpute: a generalized two-step Lasso approach to impute missing values in label-free mass spectrum analysis.

Li Q, Fisher K, Meng W, Fang B, Welsh E, Haura EB, Koomen JM, Eschrich SA, Fridley BL, Chen YA. Li Q, et al. Bioinformatics. 2020 Jan 1;36(1):257-263. doi: 10.1093/bioinformatics/btz488. Bioinformatics. 2020. PMID: 31199438 Free PMC article.

9

The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites.

Chapron BD, Dinh JC, Toren PC, Gaedigk A, Leeder JS. Chapron BD, et al. Drug Metab Dispos. 2020 Nov;48(11):1113-1120. doi: 10.1124/dmd.120.000188. Epub 2020 Aug 26. Drug Metab Dispos. 2020. PMID: 32847865 Free PMC article.

10

Intensive and prolonged urine collection in preterm infants reveals three distinct indomethacin metabolic patterns: potential implications for drug dosing.

Lewis T, Van Haandel L, Scott A, Leeder JS. Lewis T, et al. Pediatr Res. 2018 Sep;84(3):325-327. doi: 10.1038/s41390-018-0051-7. Epub 2018 Jul 2. Pediatr Res. 2018. PMID: 29967531 Free PMC article. No abstract available.

11

Who Believes They Are "Just Average": Informing the Treatment of Individual Patients Using Population Data.

Leeder JS. Leeder JS. Clin Pharmacol Ther. 2019 Nov;106(5):939-941. doi: 10.1002/cpt.1612. Epub 2019 Sep 11. Clin Pharmacol Ther. 2019. PMID: 31509232 Free PMC article. No abstract available.

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