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199 results
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A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons.
Meijer M, Rehbach K, Brunner JW, Classen JA, Lammertse HCA, van Linge LA, Schut D, Krutenko T, Hebisch M, Cornelisse LN, Sullivan PF, Peitz M, Toonen RF, Brüstle O, Verhage M. Meijer M, et al. Among authors: brustle o. Cell Rep. 2019 May 14;27(7):2199-2211.e6. doi: 10.1016/j.celrep.2019.04.058. Cell Rep. 2019. PMID: 31091456 Free article.
An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons.
Rhee HJ, Shaib AH, Rehbach K, Lee C, Seif P, Thomas C, Gideons E, Guenther A, Krutenko T, Hebisch M, Peitz M, Brose N, Brüstle O, Rhee JS. Rhee HJ, et al. Among authors: brustle o. Cell Rep. 2019 May 14;27(7):2212-2228.e7. doi: 10.1016/j.celrep.2019.04.059. Cell Rep. 2019. PMID: 31091457 Free article.
Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.
Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, Sawa A, Soldner F, Song H, Studer L, Temple S, Vaccarino FM, Wu J, Vanderhaeghen P, Gage FH, Jaenisch R. Brennand KJ, et al. Among authors: brustle o. Stem Cell Reports. 2015 Dec 8;5(6):933-945. doi: 10.1016/j.stemcr.2015.10.011. Epub 2015 Nov 21. Stem Cell Reports. 2015. PMID: 26610635 Free PMC article.
Adult germ line stem cells as a source of functional neurons and glia.
Glaser T, Opitz T, Kischlat T, Konang R, Sasse P, Fleischmann BK, Engel W, Nayernia K, Brüstle O. Glaser T, et al. Among authors: brustle o. Stem Cells. 2008 Sep;26(9):2434-43. doi: 10.1634/stemcells.2008-0163. Epub 2008 Jul 17. Stem Cells. 2008. PMID: 18635869 Free article.
Residual tumor cells are unique cellular targets in glioblastoma.
Glas M, Rath BH, Simon M, Reinartz R, Schramme A, Trageser D, Eisenreich R, Leinhaas A, Keller M, Schildhaus HU, Garbe S, Steinfarz B, Pietsch T, Steindler DA, Schramm J, Herrlinger U, Brüstle O, Scheffler B. Glas M, et al. Among authors: brustle o. Ann Neurol. 2010 Aug;68(2):264-9. doi: 10.1002/ana.22036. Ann Neurol. 2010. PMID: 20695020 Free PMC article.
Direct conversion of fibroblasts into stably expandable neural stem cells.
Thier M, Wörsdörfer P, Lakes YB, Gorris R, Herms S, Opitz T, Seiferling D, Quandel T, Hoffmann P, Nöthen MM, Brüstle O, Edenhofer F. Thier M, et al. Among authors: brustle o. Cell Stem Cell. 2012 Apr 6;10(4):473-9. doi: 10.1016/j.stem.2012.03.003. Epub 2012 Mar 22. Cell Stem Cell. 2012. PMID: 22445518 Free article.
Embryonic stem cell-based modeling of tau pathology in human neurons.
Mertens J, Stüber K, Poppe D, Doerr J, Ladewig J, Brüstle O, Koch P. Mertens J, et al. Among authors: brustle o. Am J Pathol. 2013 May;182(5):1769-79. doi: 10.1016/j.ajpath.2013.01.043. Epub 2013 Mar 13. Am J Pathol. 2013. PMID: 23499461 Free article.
Plastin 3 is upregulated in iPSC-derived motoneurons from asymptomatic SMN1-deleted individuals.
Heesen L, Peitz M, Torres-Benito L, Hölker I, Hupperich K, Dobrindt K, Jungverdorben J, Ritzenhofen S, Weykopf B, Eckert D, Hosseini-Barkooie SM, Storbeck M, Fusaki N, Lonigro R, Heller R, Kye MJ, Brüstle O, Wirth B. Heesen L, et al. Among authors: brustle o. Cell Mol Life Sci. 2016 May;73(10):2089-104. doi: 10.1007/s00018-015-2084-y. Epub 2015 Nov 16. Cell Mol Life Sci. 2016. PMID: 26573968
Modeling psychiatric disorders: from genomic findings to cellular phenotypes.
Falk A, Heine VM, Harwood AJ, Sullivan PF, Peitz M, Brüstle O, Shen S, Sun YM, Glover JC, Posthuma D, Djurovic S. Falk A, et al. Among authors: brustle o. Mol Psychiatry. 2016 Sep;21(9):1167-79. doi: 10.1038/mp.2016.89. Epub 2016 May 31. Mol Psychiatry. 2016. PMID: 27240529 Free PMC article. Review.
Reciprocal Regulation between Bifunctional miR-9/9(∗) and its Transcriptional Modulator Notch in Human Neural Stem Cell Self-Renewal and Differentiation.
Roese-Koerner B, Stappert L, Berger T, Braun NC, Veltel M, Jungverdorben J, Evert BO, Peitz M, Borghese L, Brüstle O. Roese-Koerner B, et al. Among authors: brustle o. Stem Cell Reports. 2016 Aug 9;7(2):207-19. doi: 10.1016/j.stemcr.2016.06.008. Epub 2016 Jul 14. Stem Cell Reports. 2016. PMID: 27426040 Free PMC article.
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation.
Sheng C, Jungverdorben J, Wiethoff H, Lin Q, Flitsch LJ, Eckert D, Hebisch M, Fischer J, Kesavan J, Weykopf B, Schneider L, Holtkamp D, Beck H, Till A, Wüllner U, Ziller MJ, Wagner W, Peitz M, Brüstle O. Sheng C, et al. Among authors: brustle o. Nat Commun. 2018 Oct 2;9(1):4047. doi: 10.1038/s41467-018-06398-5. Nat Commun. 2018. PMID: 30279449 Free PMC article.
Nucleofection of human embryonic stem cells.
Siemen H, Nolden L, Terstegge S, Koch P, Brüstle O. Siemen H, et al. Among authors: brustle o. Methods Mol Biol. 2008;423:131-8. doi: 10.1007/978-1-59745-194-9_8. Methods Mol Biol. 2008. PMID: 18370194
Hypomorphic mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia.
Minnerop M, Kurzwelly D, Wagner H, Soehn AS, Reichbauer J, Tao F, Rattay TW, Peitz M, Rehbach K, Giorgetti A, Pyle A, Thiele H, Altmüller J, Timmann D, Karaca I, Lennarz M, Baets J, Hengel H, Synofzik M, Atasu B, Feely S, Kennerson M, Stendel C, Lindig T, Gonzalez MA, Stirnberg R, Sturm M, Roeske S, Jung J, Bauer P, Lohmann E, Herms S, Heilmann-Heimbach S, Nicholson G, Mahanjah M, Sharkia R, Carloni P, Brüstle O, Klopstock T, Mathews KD, Shy ME, de Jonghe P, Chinnery PF, Horvath R, Kohlhase J, Schmitt I, Wolf M, Greschus S, Amunts K, Maier W, Schöls L, Nürnberg P, Zuchner S, Klockgether T, Ramirez A, Schüle R. Minnerop M, et al. Among authors: brustle o. Brain. 2017 Jun 1;140(6):1561-1578. doi: 10.1093/brain/awx095. Brain. 2017. PMID: 28459997 Free PMC article.
Neuropathology and pathogenesis of HIV encephalopathies.
Wiestler OD, Leib SL, Brüstle O, Spiegel H, Kleihues P. Wiestler OD, et al. Among authors: brustle o. Acta Histochem Suppl. 1992;42:107-14. Acta Histochem Suppl. 1992. PMID: 1584955 Review.
Functional integration of embryonic stem cell-derived neurons in vivo.
Wernig M, Benninger F, Schmandt T, Rade M, Tucker KL, Büssow H, Beck H, Brüstle O. Wernig M, et al. Among authors: brustle o. J Neurosci. 2004 Jun 2;24(22):5258-68. doi: 10.1523/JNEUROSCI.0428-04.200. J Neurosci. 2004. PMID: 15175396 Free PMC article.
Nucleofection of human embryonic stem cells.
Siemen H, Nix M, Endl E, Koch P, Itskovitz-Eldor J, Brüstle O. Siemen H, et al. Among authors: brustle o. Stem Cells Dev. 2005 Aug;14(4):378-83. doi: 10.1089/scd.2005.14.378. Stem Cells Dev. 2005. PMID: 16137226
Automated maintenance of embryonic stem cell cultures.
Terstegge S, Laufenberg I, Pochert J, Schenk S, Itskovitz-Eldor J, Endl E, Brüstle O. Terstegge S, et al. Among authors: brustle o. Biotechnol Bioeng. 2007 Jan 1;96(1):195-201. doi: 10.1002/bit.21061. Biotechnol Bioeng. 2007. PMID: 16960892
Sirt1 contributes critically to the redox-dependent fate of neural progenitors.
Prozorovski T, Schulze-Topphoff U, Glumm R, Baumgart J, Schröter F, Ninnemann O, Siegert E, Bendix I, Brüstle O, Nitsch R, Zipp F, Aktas O. Prozorovski T, et al. Among authors: brustle o. Nat Cell Biol. 2008 Apr;10(4):385-94. doi: 10.1038/ncb1700. Epub 2008 Mar 16. Nat Cell Biol. 2008. PMID: 18344989
Induction of pluripotency in adult unipotent germline stem cells.
Ko K, Tapia N, Wu G, Kim JB, Bravo MJ, Sasse P, Glaser T, Ruau D, Han DW, Greber B, Hausdörfer K, Sebastiano V, Stehling M, Fleischmann BK, Brüstle O, Zenke M, Schöler HR. Ko K, et al. Among authors: brustle o. Cell Stem Cell. 2009 Jul 2;5(1):87-96. doi: 10.1016/j.stem.2009.05.025. Cell Stem Cell. 2009. PMID: 19570517 Free article.
The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair.
Corsini NS, Sancho-Martinez I, Laudenklos S, Glagow D, Kumar S, Letellier E, Koch P, Teodorczyk M, Kleber S, Klussmann S, Wiestler B, Brüstle O, Mueller W, Gieffers C, Hill O, Thiemann M, Seedorf M, Gretz N, Sprengel R, Celikel T, Martin-Villalba A. Corsini NS, et al. Among authors: brustle o. Cell Stem Cell. 2009 Aug 7;5(2):178-90. doi: 10.1016/j.stem.2009.05.004. Cell Stem Cell. 2009. PMID: 19664992 Free article.
The nomenclature system should be sustainable, but also practical.
Higashi H, Brüstle O, Daley GQ, Yamanaka S. Higashi H, et al. Among authors: brustle o. Cell Stem Cell. 2011 Jun 3;8(6):606-7. doi: 10.1016/j.stem.2011.05.010. Cell Stem Cell. 2011. PMID: 21624802 Free article. No abstract available.
Automated selection and harvesting of pluripotent stem cell colonies.
Haupt S, Grützner J, Thier MC, Kallweit T, Rath BH, Laufenberg I, Forgber M, Eberhardt J, Edenhofer F, Brüstle O. Haupt S, et al. Among authors: brustle o. Biotechnol Appl Biochem. 2012 Mar-Apr;59(2):77-87. doi: 10.1002/bab.1014. Biotechnol Appl Biochem. 2012. PMID: 23586788
Axonal regeneration. Systemic administration of epothilone B promotes axon regeneration after spinal cord injury.
Ruschel J, Hellal F, Flynn KC, Dupraz S, Elliott DA, Tedeschi A, Bates M, Sliwinski C, Brook G, Dobrindt K, Peitz M, Brüstle O, Norenberg MD, Blesch A, Weidner N, Bunge MB, Bixby JL, Bradke F. Ruschel J, et al. Among authors: brustle o. Science. 2015 Apr 17;348(6232):347-52. doi: 10.1126/science.aaa2958. Epub 2015 Mar 12. Science. 2015. PMID: 25765066 Free PMC article.
Whole-brain 3D mapping of human neural transplant innervation.
Doerr J, Schwarz MK, Wiedermann D, Leinhaas A, Jakobs A, Schloen F, Schwarz I, Diedenhofen M, Braun NC, Koch P, Peterson DA, Kubitscheck U, Hoehn M, Brüstle O. Doerr J, et al. Among authors: brustle o. Nat Commun. 2017 Jan 19;8:14162. doi: 10.1038/ncomms14162. Nat Commun. 2017. PMID: 28102196 Free PMC article.
Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience.
De Sousa PA, Steeg R, Wachter E, Bruce K, King J, Hoeve M, Khadun S, McConnachie G, Holder J, Kurtz A, Seltmann S, Dewender J, Reimann S, Stacey G, O'Shea O, Chapman C, Healy L, Zimmermann H, Bolton B, Rawat T, Atkin I, Veiga A, Kuebler B, Serano BM, Saric T, Hescheler J, Brüstle O, Peitz M, Thiele C, Geijsen N, Holst B, Clausen C, Lako M, Armstrong L, Gupta SK, Kvist AJ, Hicks R, Jonebring A, Brolén G, Ebneth A, Cabrera-Socorro A, Foerch P, Geraerts M, Stummann TC, Harmon S, George C, Streeter I, Clarke L, Parkinson H, Harrison PW, Faulconbridge A, Cherubin L, Burdett T, Trigueros C, Patel MJ, Lucas C, Hardy B, Predan R, Dokler J, Brajnik M, Keminer O, Pless O, Gribbon P, Claussen C, Ringwald A, Kreisel B, Courtney A, Allsopp TE. De Sousa PA, et al. Among authors: o shea o, brustle o. Stem Cell Res. 2017 Apr;20:105-114. doi: 10.1016/j.scr.2017.03.002. Epub 2017 Mar 7. Stem Cell Res. 2017. PMID: 28334554 Free article.
Correction: MicroRNA-Based Promotion of Human Neuronal Differentiation and Subtype Specification.
Stappert L, Borghese L, Roese-Koerner B, Weinhold S, Koch P, Terstegge S, Uhrberg M, Wernet P, Brüstle O. Stappert L, et al. Among authors: brustle o. PLoS One. 2013 Sep 12;8(9):10.1371/annotation/b03fbc42-8f70-4873-9cce-854e48249a13. doi: 10.1371/annotation/b03fbc42-8f70-4873-9cce-854e48249a13. eCollection 2013. PLoS One. 2013. PMID: 29294475 Free PMC article.
199 results