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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1993 1
1994 3
1995 4
1996 6
1997 5
1998 5
1999 10
2000 1
2001 6
2002 12
2003 8
2004 14
2005 21
2006 23
2007 27
2008 29
2009 26
2010 35
2011 36
2012 37
2013 34
2014 64
2015 68
2016 75
2017 68
2018 68
2019 82
2020 87
2021 78
2022 73
2023 16
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938 results
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Page 1
GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data.
Ajaib S, Lodha D, Pollock S, Hemmings G, Finetti MA, Gusnanto A, Chakrabarty A, Ismail A, Wilson E, Varn FS, Hunter B, Filby A, Brockman AA, McDonald D, Verhaak RGW, Ihrie RA, Stead LF. Ajaib S, et al. Among authors: ihrie ra. Neuro Oncol. 2023 Jan 23:noad021. doi: 10.1093/neuonc/noad021. Online ahead of print. Neuro Oncol. 2023. PMID: 36689332
Protrusion growth driven by myosin-generated force.
Fitz GN, Weck ML, Bodnya C, Perkins OL, Tyska MJ. Fitz GN, et al. Among authors: tyska mj. Dev Cell. 2023 Jan 9;58(1):18-33.e6. doi: 10.1016/j.devcel.2022.12.001. Dev Cell. 2023. PMID: 36626869
Feedback in the β-catenin destruction complex imparts bistability and cellular memory.
Cantoria MJ, Alizadeh E, Ravi J, Varghese RP, Bunnag N, Pond KW, Kettenbach AN, Ahmed Y, Paek AL, Tyson JJ, Doubrovinski K, Lee E, Thorne CA. Cantoria MJ, et al. Among authors: lee e. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2208787120. doi: 10.1073/pnas.2208787120. Epub 2023 Jan 4. Proc Natl Acad Sci U S A. 2023. PMID: 36598937
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models.
Teuscher KB, Chowdhury S, Meyers KM, Tian J, Sai J, Van Meveren M, South TM, Sensintaffar JL, Rietz TA, Goswami S, Wang J, Grieb BC, Lorey SL, Howard GC, Liu Q, Moore WJ, Stott GM, Tansey WP, Lee T, Fesik SW. Teuscher KB, et al. Among authors: tansey wp. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2211297120. doi: 10.1073/pnas.2211297120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574664 Free article.
Learning cell identity in immunology, neuroscience, and cancer.
Medina S, Ihrie RA, Irish JM. Medina S, et al. Among authors: ihrie ra, irish jm. Semin Immunopathol. 2022 Dec 19:1-14. doi: 10.1007/s00281-022-00976-y. Online ahead of print. Semin Immunopathol. 2022. PMID: 36534139 Free PMC article. Review.
Editorial: Women in Gastrointestinal Sciences: 2021.
Luhtala N, DelGiorno KE. Luhtala N, et al. Among authors: delgiorno ke. Front Physiol. 2022 Oct 19;13:1048724. doi: 10.3389/fphys.2022.1048724. eCollection 2022. Front Physiol. 2022. PMID: 36338474 Free PMC article. No abstract available.
Cross-scale Attention Guided Multi-instance Learning for Crohn's Disease Diagnosis with Pathological Images.
Deng R, Cui C, Remedios LW, Bao S, Womick RM, Chiron S, Li J, Roland JT, Lau KS, Liu Q, Wilson KT, Wang Y, Coburn LA, Landman BA, Huo Y. Deng R, et al. Among authors: lau ks. Multiscale Multimodal Med Imaging (2022). 2022 Sep;13594:24-33. doi: 10.1007/978-3-031-18814-5_3. Epub 2022 Oct 12. Multiscale Multimodal Med Imaging (2022). 2022. PMID: 36331283 Free PMC article.
Analysis of tripartite Synaptotagmin-1-SNARE-complexin-1 complexes in solution.
Jaczynska K, Esquivies L, Pfuetzner RA, Alten B, Brewer KD, Zhou Q, Kavalali ET, Brunger AT, Rizo J. Jaczynska K, et al. Among authors: zhou q. FEBS Open Bio. 2023 Jan;13(1):26-50. doi: 10.1002/2211-5463.13503. Epub 2022 Nov 16. FEBS Open Bio. 2023. PMID: 36305864 Free PMC article.
Fundamental roles for inter-organelle communication in aging.
Donahue EKF, Ruark EM, Burkewitz K. Donahue EKF, et al. Among authors: burkewitz k. Biochem Soc Trans. 2022 Oct 31;50(5):1389-1402. doi: 10.1042/BST20220519. Biochem Soc Trans. 2022. PMID: 36305642 Free PMC article. Review.
Resolution doubling in light-sheet microscopy via oblique plane structured illumination.
Chen B, Chang BJ, Roudot P, Zhou F, Sapoznik E, Marlar-Pavey M, Hayes JB, Brown PT, Zeng CW, Lambert T, Friedman JR, Zhang CL, Burnette DT, Shepherd DP, Dean KM, Fiolka RP. Chen B, et al. Among authors: burnette dt. Nat Methods. 2022 Nov;19(11):1419-1426. doi: 10.1038/s41592-022-01635-8. Epub 2022 Oct 24. Nat Methods. 2022. PMID: 36280718
Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer.
Cui Zhou D, Jayasinghe RG, Chen S, Herndon JM, Iglesia MD, Navale P, Wendl MC, Caravan W, Sato K, Storrs E, Mo CK, Liu J, Southard-Smith AN, Wu Y, Naser Al Deen N, Baer JM, Fulton RS, Wyczalkowski MA, Liu R, Fronick CC, Fulton LA, Shinkle A, Thammavong L, Zhu H, Sun H, Wang LB, Li Y, Zuo C, McMichael JF, Davies SR, Appelbaum EL, Robbins KJ, Chasnoff SE, Yang X, Reeb AN, Oh C, Serasanambati M, Lal P, Varghese R, Mashl JR, Ponce J, Terekhanova NV, Yao L, Wang F, Chen L, Schnaubelt M, Lu RJ, Schwarz JK, Puram SV, Kim AH, Song SK, Shoghi KI, Lau KS, Ju T, Chen K, Chatterjee D, Hawkins WG, Zhang H, Achilefu S, Chheda MG, Oh ST, Gillanders WE, Chen F, DeNardo DG, Fields RC, Ding L. Cui Zhou D, et al. Among authors: lau ks. Nat Genet. 2022 Sep;54(9):1390-1405. doi: 10.1038/s41588-022-01157-1. Epub 2022 Aug 22. Nat Genet. 2022. PMID: 35995947 Free PMC article.
Uropathogenic Escherichia coli subverts mitochondrial metabolism to enable intracellular bacterial pathogenesis in urinary tract infection.
Beebout CJ, Robertson GL, Reinfeld BI, Blee AM, Morales GH, Brannon JR, Chazin WJ, Rathmell WK, Rathmell JC, Gama V, Hadjifrangiskou M. Beebout CJ, et al. Among authors: gama v. Nat Microbiol. 2022 Sep;7(9):1348-1360. doi: 10.1038/s41564-022-01205-w. Epub 2022 Aug 22. Nat Microbiol. 2022. PMID: 35995841 Free PMC article.
Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer.
Groves SM, Ildefonso GV, McAtee CO, Ozawa PMM, Ireland AS, Stauffer PE, Wasdin PT, Huang X, Qiao Y, Lim JS, Bader J, Liu Q, Simmons AJ, Lau KS, Iams WT, Hardin DP, Saff EB, Holmes WR, Tyson DR, Lovly CM, Rathmell JC, Marth G, Sage J, Oliver TG, Weaver AM, Quaranta V. Groves SM, et al. Among authors: weaver am, lau ks. Cell Syst. 2022 Sep 21;13(9):690-710.e17. doi: 10.1016/j.cels.2022.07.006. Epub 2022 Aug 17. Cell Syst. 2022. PMID: 35981544
Ubiquitination drives COPI priming and Golgi SNARE localization.
Date SS, Xu P, Hepowit NL, Diab NS, Best J, Xie B, Du J, Strieter ER, Jackson LP, MacGurn JA, Graham TR. Date SS, et al. Among authors: macgurn ja. Elife. 2022 Jul 29;11:e80911. doi: 10.7554/eLife.80911. Elife. 2022. PMID: 35904239 Free PMC article.
Human iPSC-derived cerebral organoids model features of Leigh syndrome and reveal abnormal corticogenesis.
Romero-Morales AI, Robertson GL, Rastogi A, Rasmussen ML, Temuri H, McElroy GS, Chakrabarty RP, Hsu L, Almonacid PM, Millis BA, Chandel NS, Cartailler JP, Gama V. Romero-Morales AI, et al. Among authors: gama v. Development. 2022 Oct 15;149(20):dev199914. doi: 10.1242/dev.199914. Epub 2022 Jul 6. Development. 2022. PMID: 35792828 Free PMC article.
CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction.
Yang D, Cho H, Tayyebi Z, Shukla A, Luo R, Dixon G, Ursu V, Stransky S, Tremmel DM, Sackett SD, Koche R, Kaplan SJ, Li QV, Park J, Zhu Z, Rosen BP, Pulecio J, Shi ZD, Bram Y, Schwartz RE, Odorico JS, Sidoli S, Wright CV, Leslie CS, Huangfu D. Yang D, et al. Among authors: wright cv. Nat Cell Biol. 2022 Jul;24(7):1064-1076. doi: 10.1038/s41556-022-00946-4. Epub 2022 Jul 4. Nat Cell Biol. 2022. PMID: 35787684 Free PMC article.
Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine.
Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker LM, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE Jr, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM. Kramer KJ, et al. Among authors: irish jm. Nat Commun. 2022 Jun 16;13(1):3466. doi: 10.1038/s41467-022-31142-5. Nat Commun. 2022. PMID: 35710908 Free PMC article.
Dysplastic Stem Cell Plasticity Functions as a Driving Force for Neoplastic Transformation of Precancerous Gastric Mucosa.
Min J, Zhang C, Bliton RJ, Caldwell B, Caplan L, Presentation KS, Park DJ, Kong SH, Lee HS, Washington MK, Kim WH, Lau KS, Magness ST, Lee HJ, Yang HK, Goldenring JR, Choi E. Min J, et al. Among authors: lau ks. Gastroenterology. 2022 Oct;163(4):875-890. doi: 10.1053/j.gastro.2022.06.021. Epub 2022 Jun 11. Gastroenterology. 2022. PMID: 35700772 Free PMC article.
Human Colon Cancer-Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice.
Drewes JL, Chen J, Markham NO, Knippel RJ, Domingue JC, Tam AJ, Chan JL, Kim L, McMann M, Stevens C, Dejea CM, Tomkovich S, Michel J, White JR, Mohammad F, Campodónico VL, Heiser CN, Wu X, Wu S, Ding H, Simner P, Carroll K, Shrubsole MJ, Anders RA, Walk ST, Jobin C, Wan F, Coffey RJ, Housseau F, Lau KS, Sears CL. Drewes JL, et al. Among authors: lau ks. Cancer Discov. 2022 Aug 5;12(8):1873-1885. doi: 10.1158/2159-8290.CD-21-1273. Cancer Discov. 2022. PMID: 35678528 Free PMC article.
Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer.
Vega PN, Nilsson A, Kumar MP, Niitsu H, Simmons AJ, Ro J, Wang J, Chen Z, Joughin BA, Li W, McKinley ET, Liu Q, Roland JT, Washington MK, Coffey RJ, Lauffenburger DA, Lau KS. Vega PN, et al. Among authors: lau ks. Front Oncol. 2022 May 4;12:878920. doi: 10.3389/fonc.2022.878920. eCollection 2022. Front Oncol. 2022. PMID: 35600339 Free PMC article.
Enteroendocrine Cell Formation Is an Early Event in Pancreatic Tumorigenesis.
Caplan LR, Vavinskaya V, Gelikman DG, Jyotsana N, Trinh VQ, Olive KP, Tan MCB, DelGiorno KE. Caplan LR, et al. Among authors: delgiorno ke. Front Physiol. 2022 Apr 27;13:865452. doi: 10.3389/fphys.2022.865452. eCollection 2022. Front Physiol. 2022. PMID: 35574446 Free PMC article.
MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors.
Brown RE, Jacobse J, Anant SA, Blunt KM, Chen B, Vega PN, Jones CT, Pilat JM, Revetta F, Gorby AH, Stengel KR, Choksi YA, Palin K, Piazuelo MB, Washington MK, Lau KS, Goettel JA, Hiebert SW, Short SP, Williams CS. Brown RE, et al. Among authors: lau ks. JCI Insight. 2022 May 23;7(10):e153045. doi: 10.1172/jci.insight.153045. JCI Insight. 2022. PMID: 35503250 Free PMC article.
A taste of the early steps in BAX activation with FLAMBE.
Gil M, Hanna MR, Gama V. Gil M, et al. Among authors: gama v. Cell Rep Methods. 2022 Mar 15;2(3):100190. doi: 10.1016/j.crmeth.2022.100190. eCollection 2022 Mar 28. Cell Rep Methods. 2022. PMID: 35475223 Free PMC article.
Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion.
Georgiadou E, Muralidharan C, Martinez M, Chabosseau P, Akalestou E, Tomas A, Wern FYS, Stylianides T, Wretlind A, Legido-Quigley C, Jones B, Lopez-Noriega L, Xu Y, Gu G, Alsabeeh N, Cruciani-Guglielmacci C, Magnan C, Ibberson M, Leclerc I, Ali Y, Soleimanpour SA, Linnemann AK, Rodriguez TA, Rutter GA. Georgiadou E, et al. Among authors: gu g. Diabetes. 2022 Jul 1;71(7):1472-1489. doi: 10.2337/db21-0800. Diabetes. 2022. PMID: 35472764 Free PMC article.
Inhibition of calcium-triggered secretion by hydrocarbon-stapled peptides.
Lai Y, Fois G, Flores JR, Tuvim MJ, Zhou Q, Yang K, Leitz J, Peters J, Zhang Y, Pfuetzner RA, Esquivies L, Jones P, Frick M, Dickey BF, Brunger AT. Lai Y, et al. Among authors: zhou q. Nature. 2022 Mar;603(7903):949-956. doi: 10.1038/s41586-022-04543-1. Epub 2022 Mar 23. Nature. 2022. PMID: 35322233 Free PMC article.
The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation.
Borza CM, Bolas G, Zhang X, Browning Monroe MB, Zhang MZ, Meiler J, Skwark MJ, Harris RC, Lapierre LA, Goldenring JR, Hook M, Rivera J, Brown KL, Leitinger B, Tyska MJ, Moser M, Böttcher RT, Zent R, Pozzi A. Borza CM, et al. Among authors: tyska mj. Front Cell Dev Biol. 2022 Mar 3;10:836797. doi: 10.3389/fcell.2022.836797. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35309920 Free PMC article.
Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells.
Florian AC, Woodley CM, Wang J, Grieb BC, Slota MJ, Guerrazzi K, Hsu CY, Matlock BK, Flaherty DK, Lorey SL, Fesik SW, Howard GC, Liu Q, Weissmiller AM, Tansey WP. Florian AC, et al. Among authors: tansey wp. NAR Cancer. 2022 Mar 3;4(1):zcac007. doi: 10.1093/narcan/zcac007. eCollection 2022 Mar. NAR Cancer. 2022. PMID: 35252869 Free PMC article.
WIN site inhibition disrupts a subset of WDR5 function.
Siladi AJ, Wang J, Florian AC, Thomas LR, Creighton JH, Matlock BK, Flaherty DK, Lorey SL, Howard GC, Fesik SW, Weissmiller AM, Liu Q, Tansey WP. Siladi AJ, et al. Among authors: tansey wp. Sci Rep. 2022 Feb 3;12(1):1848. doi: 10.1038/s41598-022-05947-9. Sci Rep. 2022. PMID: 35115608 Free PMC article.
Modeling tuberous sclerosis with organoids.
Ihrie RA, Henske EP. Ihrie RA, et al. Science. 2022 Jan 28;375(6579):382-383. doi: 10.1126/science.abn6158. Epub 2022 Jan 27. Science. 2022. PMID: 35084978
Nonclassical Monocytes Are Prone to Migrate Into Tumor in Diffuse Large B-Cell Lymphoma.
Le Gallou S, Lhomme F, Irish JM, Mingam A, Pangault C, Monvoisin C, Ferrant J, Azzaoui I, Rossille D, Bouabdallah K, Damaj G, Cartron G, Godmer P, Le Gouill S, Casasnovas RO, Molina TJ, Houot R, Lamy T, Tarte K, Fest T, Roussel M. Le Gallou S, et al. Among authors: irish jm. Front Immunol. 2021 Dec 16;12:755623. doi: 10.3389/fimmu.2021.755623. eCollection 2021. Front Immunol. 2021. PMID: 34975843 Free PMC article.
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.
Chen B, Scurrah CR, McKinley ET, Simmons AJ, Ramirez-Solano MA, Zhu X, Markham NO, Heiser CN, Vega PN, Rolong A, Kim H, Sheng Q, Drewes JL, Zhou Y, Southard-Smith AN, Xu Y, Ro J, Jones AL, Revetta F, Berry LD, Niitsu H, Islam M, Pelka K, Hofree M, Chen JH, Sarkizova S, Ng K, Giannakis M, Boland GM, Aguirre AJ, Anderson AC, Rozenblatt-Rosen O, Regev A, Hacohen N, Kawasaki K, Sato T, Goettel JA, Grady WM, Zheng W, Washington MK, Cai Q, Sears CL, Goldenring JR, Franklin JL, Su T, Huh WJ, Vandekar S, Roland JT, Liu Q, Coffey RJ, Shrubsole MJ, Lau KS. Chen B, et al. Among authors: lau ks. Cell. 2021 Dec 22;184(26):6262-6280.e26. doi: 10.1016/j.cell.2021.11.031. Epub 2021 Dec 14. Cell. 2021. PMID: 34910928 Free PMC article.
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.
Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. Zhang Q, et al. Among authors: burnette dt. Nat Cell Biol. 2021 Dec;23(12):1240-1254. doi: 10.1038/s41556-021-00805-8. Epub 2021 Dec 9. Nat Cell Biol. 2021. PMID: 34887515 Free PMC article.
Glypicans and cytonemes unite to distribute Wnt ligands.
Waghmare I, Page-McCaw A. Waghmare I, et al. Among authors: page mccaw a. J Cell Biol. 2021 Dec 6;220(12):e202110033. doi: 10.1083/jcb.202110033. Epub 2021 Nov 15. J Cell Biol. 2021. PMID: 34779856 Free PMC article.
Two New Neutrophil Subsets Define a Discriminating Sepsis Signature.
Meghraoui-Kheddar A, Chousterman BG, Guillou N, Barone SM, Granjeaud S, Vallet H, Corneau A, Guessous K, de Roquetaillade C, Boissonnas A, Irish JM, Combadière C. Meghraoui-Kheddar A, et al. Among authors: irish jm. Am J Respir Crit Care Med. 2022 Jan 1;205(1):46-59. doi: 10.1164/rccm.202104-1027OC. Am J Respir Crit Care Med. 2022. PMID: 34731593 Free article.
Single-Cell Transcriptomics Reveals a Conserved Metaplasia Program in Pancreatic Injury.
Ma Z, Lytle NK, Chen B, Jyotsana N, Novak SW, Cho CJ, Caplan L, Ben-Levy O, Neininger AC, Burnette DT, Trinh VQ, Tan MCB, Patterson EA, Arrojo E Drigo R, Giraddi RR, Ramos C, Means AL, Matsumoto I, Manor U, Mills JC, Goldenring JR, Lau KS, Wahl GM, DelGiorno KE. Ma Z, et al. Among authors: burnette dt, delgiorno ke, lau ks. Gastroenterology. 2022 Feb;162(2):604-620.e20. doi: 10.1053/j.gastro.2021.10.027. Epub 2021 Oct 23. Gastroenterology. 2022. PMID: 34695382
Imaging Dendritic Spines in Caenorhabditis elegans.
Cuentas-Condori A, Miller DM 3rd. Cuentas-Condori A, et al. Among authors: miller dm 3rd. J Vis Exp. 2021 Sep 27;(175). doi: 10.3791/62676. J Vis Exp. 2021. PMID: 34633371
Zones of cellular damage around pulsed-laser wounds.
O'Connor J, Akbar FB, Hutson MS, Page-McCaw A. O'Connor J, et al. Among authors: page mccaw a. PLoS One. 2021 Sep 27;16(9):e0253032. doi: 10.1371/journal.pone.0253032. eCollection 2021. PLoS One. 2021. PMID: 34570791 Free PMC article.
938 results