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Forskolin induced swelling (FIS) assay in intestinal organoids to guide eligibility for compassionate use treatment in a CF patient with a rare genotype.
J Cyst Fibros. 2022 Mar;21(2):254-257. doi: 10.1016/j.jcf.2022.01.008. Epub 2022 Jan 31.
J Cyst Fibros. 2022.
PMID: 35110005
Free article.
Clinical effect of lumacaftor/ivacaftor in F508del homozygous CF patients with FEV1 ≥ 90% predicted at baseline.
Aalbers BL, de Winter-de Groot KM, Arets HGM, Hofland RW, de Kiviet AC, van Oirschot-van de Ven MMM, Kruijswijk MA, Schotman S, Michel S, van der Ent CK, Heijerman HGM.
Aalbers BL, et al.
J Cyst Fibros. 2020 Jul;19(4):654-658. doi: 10.1016/j.jcf.2019.12.015. Epub 2020 Jan 7.
J Cyst Fibros. 2020.
PMID: 31924546
Free article.
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Females with cystic fibrosis have a larger decrease in sweat chloride in response to lumacaftor/ivacaftor compared to males.
Aalbers BL, Hofland RW, Bronsveld I, de Winter-de Groot KM, Arets HGM, de Kiviet AC, van Oirschot-van de Ven MMM, Kruijswijk MA, Schotman S, Michel S, van der Ent CK, Heijerman HGM.
Aalbers BL, et al.
J Cyst Fibros. 2021 Jan;20(1):e7-e11. doi: 10.1016/j.jcf.2020.05.004. Epub 2020 May 21.
J Cyst Fibros. 2021.
PMID: 32448708
Free article.
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Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia.
Amatngalim GD, Rodenburg LW, Aalbers BL, Raeven HH, Aarts EM, Sarhane D, Spelier S, Lefferts JW, Silva IA, Nijenhuis W, Vrendenbarg S, Kruisselbrink E, Brunsveld JE, van Drunen CM, Michel S, de Winter-de Groot KM, Heijerman HG, Kapitein LC, Amaral MD, van der Ent CK, Beekman JM.
Amatngalim GD, et al. Among authors: aalbers bl.
Life Sci Alliance. 2022 Aug 3;5(12):e202101320. doi: 10.26508/lsa.202101320.
Life Sci Alliance. 2022.
PMID: 35922154
Free PMC article.
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CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank.
Geurts MH, de Poel E, Amatngalim GD, Oka R, Meijers FM, Kruisselbrink E, van Mourik P, Berkers G, de Winter-de Groot KM, Michel S, Muilwijk D, Aalbers BL, Mullenders J, Boj SF, Suen SWF, Brunsveld JE, Janssens HM, Mall MA, Graeber SY, van Boxtel R, van der Ent CK, Beekman JM, Clevers H.
Geurts MH, et al. Among authors: aalbers bl.
Cell Stem Cell. 2020 Apr 2;26(4):503-510.e7. doi: 10.1016/j.stem.2020.01.019. Epub 2020 Feb 20.
Cell Stem Cell. 2020.
PMID: 32084388
Free article.
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Management of Individual Patient Expectations When Starting with Highly Effective CFTR Modulators.
Aalbers BL, Bronsveld I, Hofland RW, Heijerman HGM.
Aalbers BL, et al.
J Pers Med. 2021 Aug 19;11(8):811. doi: 10.3390/jpm11080811.
J Pers Med. 2021.
PMID: 34442455
Free PMC article.
Review.
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Nasal potential difference in suspected cystic fibrosis patients with 5T polymorphism.
Aalbers BL, Yaakov Y, Derichs N, Simmonds NJ, De Wachter E, Melotti P, De Boeck K, Leal T, Tümmler B, Wilschanski M, Bronsveld I.
Aalbers BL, et al.
J Cyst Fibros. 2020 Jul;19(4):627-631. doi: 10.1016/j.jcf.2019.07.001. Epub 2019 Jul 19.
J Cyst Fibros. 2020.
PMID: 31331863
Free article.
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Radiological and long-term clinical response to elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis with advanced lung disease.
Aalbers BL, Mohamed Hoesein FAA, Hofland RW, Bronsveld I, Kruijswijk MA, Schotman S, Slingerland CW, Panhuis H, van der Ent CK, Heijerman HGM.
Aalbers BL, et al.
Pediatr Pulmonol. 2023 Aug;58(8):2317-2322. doi: 10.1002/ppul.26486. Epub 2023 May 24.
Pediatr Pulmonol. 2023.
PMID: 37222401
Clinical Trial.
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