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Page 1
Towards clinical application of prediction models for transition to psychosis: A systematic review and external validation study in the PRONIA sample.
Rosen M, Betz LT, Schultze-Lutter F, Chisholm K, Haidl TK, Kambeitz-Ilankovic L, Bertolino A, Borgwardt S, Brambilla P, Lencer R, Meisenzahl E, Ruhrmann S, Salokangas RKR, Upthegrove R, Wood SJ, Koutsouleris N, Kambeitz J; PRONIA Consortium. Rosen M, et al. Neurosci Biobehav Rev. 2021 Jun;125:478-492. doi: 10.1016/j.neubiorev.2021.02.032. Epub 2021 Feb 23. Neurosci Biobehav Rev. 2021. PMID: 33636198
Neuroanatomical abnormalities that predate the onset of psychosis: a multicenter study.
Mechelli A, Riecher-Rössler A, Meisenzahl EM, Tognin S, Wood SJ, Borgwardt SJ, Koutsouleris N, Yung AR, Stone JM, Phillips LJ, McGorry PD, Valli I, Velakoulis D, Woolley J, Pantelis C, McGuire P. Mechelli A, et al. Arch Gen Psychiatry. 2011 May;68(5):489-95. doi: 10.1001/archgenpsychiatry.2011.42. Arch Gen Psychiatry. 2011. PMID: 21536978
Induction of psychosis by Δ9-tetrahydrocannabinol reflects modulation of prefrontal and striatal function during attentional salience processing.
Bhattacharyya S, Crippa JA, Allen P, Martin-Santos R, Borgwardt S, Fusar-Poli P, Rubia K, Kambeitz J, O'Carroll C, Seal ML, Giampietro V, Brammer M, Zuardi AW, Atakan Z, McGuire PK. Bhattacharyya S, et al. Arch Gen Psychiatry. 2012 Jan;69(1):27-36. doi: 10.1001/archgenpsychiatry.2011.161. Arch Gen Psychiatry. 2012. PMID: 22213786
Whither the attenuated psychosis syndrome?
Yung AR, Woods SW, Ruhrmann S, Addington J, Schultze-Lutter F, Cornblatt BA, Amminger GP, Bechdolf A, Birchwood M, Borgwardt S, Cannon TD, de Haan L, French P, Fusar-Poli P, Keshavan M, Klosterkötter J, Kwon JS, McGorry PD, McGuire P, Mizuno M, Morrison AP, Riecher-Rössler A, Salokangas RK, Seidman LJ, Suzuki M, Valmaggia L, van der Gaag M, Wood SJ, McGlashan TH. Yung AR, et al. Schizophr Bull. 2012 Nov;38(6):1130-4. doi: 10.1093/schbul/sbs108. Schizophr Bull. 2012. PMID: 23144056 Free PMC article. No abstract available.
The psychosis high-risk state: a comprehensive state-of-the-art review.
Fusar-Poli P, Borgwardt S, Bechdolf A, Addington J, Riecher-Rössler A, Schultze-Lutter F, Keshavan M, Wood S, Ruhrmann S, Seidman LJ, Valmaggia L, Cannon T, Velthorst E, De Haan L, Cornblatt B, Bonoldi I, Birchwood M, McGlashan T, Carpenter W, McGorry P, Klosterkötter J, McGuire P, Yung A. Fusar-Poli P, et al. JAMA Psychiatry. 2013 Jan;70(1):107-20. doi: 10.1001/jamapsychiatry.2013.269. JAMA Psychiatry. 2013. PMID: 23165428 Free PMC article. Review.
Reduced parahippocampal cortical thickness in subjects at ultra-high risk for psychosis.
Tognin S, Riecher-Rössler A, Meisenzahl EM, Wood SJ, Hutton C, Borgwardt SJ, Koutsouleris N, Yung AR, Allen P, Phillips LJ, McGorry PD, Valli I, Velakoulis D, Nelson B, Woolley J, Pantelis C, McGuire P, Mechelli A. Tognin S, et al. Psychol Med. 2014 Feb;44(3):489-98. doi: 10.1017/S0033291713000998. Epub 2013 May 10. Psychol Med. 2014. PMID: 23659473 Free PMC article.
[Prediction of psychosis by stepwise multilevel assessment--the Basel FePsy (Early Recognition of Psychosis)-Project].
Riecher-Rössler A, Aston J, Borgwardt S, Bugra H, Fuhr P, Gschwandtner U, Koutsouleris N, Pflueger M, Tamagni C, Radü EW, Rapp C, Smieskova R, Studerus E, Walter A, Zimmermann R. Riecher-Rössler A, et al. Fortschr Neurol Psychiatr. 2013 May;81(5):265-75. doi: 10.1055/s-0033-1335017. Epub 2013 May 21. Fortschr Neurol Psychiatr. 2013. PMID: 23695791 German.
Classifying individuals at high-risk for psychosis based on functional brain activity during working memory processing.
Bendfeldt K, Smieskova R, Koutsouleris N, Klöppel S, Schmidt A, Walter A, Harrisberger F, Wrege J, Simon A, Taschler B, Nichols T, Riecher-Rössler A, Lang UE, Radue EW, Borgwardt S. Bendfeldt K, et al. Neuroimage Clin. 2015 Sep 30;9:555-63. doi: 10.1016/j.nicl.2015.09.015. eCollection 2015. Neuroimage Clin. 2015. PMID: 26640767 Free PMC article.
Heterogeneity of Psychosis Risk Within Individuals at Clinical High Risk: A Meta-analytical Stratification.
Fusar-Poli P, Cappucciati M, Borgwardt S, Woods SW, Addington J, Nelson B, Nieman DH, Stahl DR, Rutigliano G, Riecher-Rössler A, Simon AE, Mizuno M, Lee TY, Kwon JS, Lam MM, Perez J, Keri S, Amminger P, Metzler S, Kawohl W, Rössler W, Lee J, Labad J, Ziermans T, An SK, Liu CC, Woodberry KA, Braham A, Corcoran C, McGorry P, Yung AR, McGuire PK. Fusar-Poli P, et al. JAMA Psychiatry. 2016 Feb;73(2):113-20. doi: 10.1001/jamapsychiatry.2015.2324. JAMA Psychiatry. 2016. PMID: 26719911
Neuroimaging in moderate MDMA use: A systematic review.
Mueller F, Lenz C, Steiner M, Dolder PC, Walter M, Lang UE, Liechti ME, Borgwardt S. Mueller F, et al. Neurosci Biobehav Rev. 2016 Mar;62:21-34. doi: 10.1016/j.neubiorev.2015.12.010. Epub 2015 Dec 30. Neurosci Biobehav Rev. 2016. PMID: 26746590 Free article.
Ventricular volumes across stages of schizophrenia and other psychoses.
Berger GE, Bartholomeusz CF, Wood SJ, Ang A, Phillips LJ, Proffitt T, Brewer WJ, Smith DJ, Nelson B, Lin A, Borgwardt S, Velakoulis D, Yung AR, McGorry PD, Pantelis C. Berger GE, et al. Aust N Z J Psychiatry. 2017 Oct;51(10):1041-1051. doi: 10.1177/0004867417715914. Epub 2017 Jul 1. Aust N Z J Psychiatry. 2017. PMID: 28670977
Prediction Models of Functional Outcomes for Individuals in the Clinical High-Risk State for Psychosis or With Recent-Onset Depression: A Multimodal, Multisite Machine Learning Analysis.
Koutsouleris N, Kambeitz-Ilankovic L, Ruhrmann S, Rosen M, Ruef A, Dwyer DB, Paolini M, Chisholm K, Kambeitz J, Haidl T, Schmidt A, Gillam J, Schultze-Lutter F, Falkai P, Reiser M, Riecher-Rössler A, Upthegrove R, Hietala J, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Beque D, Brambilla P, Borgwardt S; PRONIA Consortium. Koutsouleris N, et al. JAMA Psychiatry. 2018 Nov 1;75(11):1156-1172. doi: 10.1001/jamapsychiatry.2018.2165. JAMA Psychiatry. 2018. PMID: 30267047 Free PMC article.
Gender differences of patients at-risk for psychosis regarding symptomatology, drug use, comorbidity and functioning - Results from the EU-GEI study.
Menghini-Müller S, Studerus E, Ittig S, Heitz U, Egloff L, Andreou C, Valmaggia LR, Kempton MJ, van der Gaag M, de Haan L, Nelson B, Barrantes-Vidal N, Nordentoft M, Ruhrmann S, Sachs G, Rutten BP, Os JV, Riecher-Rössler A; EU-GEI High Risk Study Group; McGuire P, Valmaggia LR, Kempton MJ, Calem M, Tognin S, Modinos G, de Haan L, van der Gaag M, Velthorst E, Kraan TC, van Dam DS, Burger N, Nelson B, McGorry P, Amminger GP, Pantelis C, Politis A, Goodall J, Riecher-Rössler A, Borgwardt S, Rapp C, Ittig S, Studerus E, Smieskova R, Bressan R, Gadelha A, Brietzke E, Asevedo G, Asevedo E, Zugman A, Barrantes-Vidal N, Domínguez-Martínez T, Racioppi A, Cristóbal-Narváez P, Kwapil TR, Monsonet M, Kazes M, Daban C, Bourgin J, Gay O, Mam-Lam-Fook C, Krebs MO, Nordholm D, Randers L, Krakauer K, Glenthøj L, Glenthøj B, Nordentoft M, Ruhrmann S, Gebhard D, Arnhold J, Klosterkötter J, Sachs G, Lasser I, Winklbaur B, Delespaul PA, Rutten BP, van Os J. Menghini-Müller S, et al. Eur Psychiatry. 2019 Jun;59:52-59. doi: 10.1016/j.eurpsy.2019.04.007. Epub 2019 May 7. Eur Psychiatry. 2019. PMID: 31075522
Common brain disorders are associated with heritable patterns of apparent aging of the brain.
Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Córdova-Palomera A, Dale AM, de Quervain DJF, Di Carlo P, Djurovic S, Dørum ES, Eisenacher S, Elvsåshagen T, Espeseth T, Fatouros-Bergman H, Flyckt L, Franke B, Frei O, Haatveit B, Håberg AK, Harbo HF, Hartman CA, Heslenfeld D, Hoekstra PJ, Høgestøl EA, Jernigan TL, Jonassen R, Jönsson EG; Karolinska Schizophrenia Project (KaSP); Kirsch P, Kłoszewska I, Kolskår KK, Landrø NI, Le Hellard S, Lesch KP, Lovestone S, Lundervold A, Lundervold AJ, Maglanoc LA, Malt UF, Mecocci P, Melle I, Meyer-Lindenberg A, Moberget T, Norbom LB, Nordvik JE, Nyberg L, Oosterlaan J, Papalino M, Papassotiropoulos A, Pauli P, Pergola G, Persson K, Richard G, Rokicki J, Sanders AM, Selbæk G, Shadrin AA, Smeland OB, Soininen H, Sowa P, Steen VM, Tsolaki M, Ulrichsen KM, Vellas B, Wang L, Westman E, Ziegler GC, Zink M, Andreassen OA, Westlye LT. Kaufmann T, et al. Nat Neurosci. 2019 Oct;22(10):1617-1623. doi: 10.1038/s41593-019-0471-7. Epub 2019 Sep 24. Nat Neurosci. 2019. PMID: 31551603 Free PMC article.
European college of neuropsychopharmacology network on the prevention of mental disorders and mental health promotion (ECNP PMD-MHP).
Fusar-Poli P, Bauer M, Borgwardt S, Bechdolf A, Correll CU, Do KQ, Domschke K, Galderisi S, Kessing LV, Koutsouleris N, Krebs MO, Lennox B, McGuire P, Meyer-Lindenberg A, Millan MJ, Nieman D, Pfennig A, Sand M, Whenert A, van Amelsvoort T, Arango C. Fusar-Poli P, et al. Eur Neuropsychopharmacol. 2019 Dec;29(12):1301-1311. doi: 10.1016/j.euroneuro.2019.09.006. Epub 2019 Oct 9. Eur Neuropsychopharmacol. 2019. PMID: 31606303 Free article. Review.
Association of Adverse Outcomes With Emotion Processing and Its Neural Substrate in Individuals at Clinical High Risk for Psychosis.
Modinos G, Kempton MJ, Tognin S, Calem M, Porffy L, Antoniades M, Mason A, Azis M, Allen P, Nelson B, McGorry P, Pantelis C, Riecher-Rössler A, Borgwardt S, Bressan R, Barrantes-Vidal N, Krebs MO, Nordentoft M, Glenthøj B, Ruhrmann S, Sachs G, Rutten B, van Os J, de Haan L, Velthorst E, van der Gaag M, Valmaggia LR, McGuire P; EU-GEI High Risk Study Group. Modinos G, et al. JAMA Psychiatry. 2020 Feb 1;77(2):190-200. doi: 10.1001/jamapsychiatry.2019.3501. JAMA Psychiatry. 2020. PMID: 31722018 Free PMC article.
Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention.
Fusar-Poli P, Salazar de Pablo G, Correll CU, Meyer-Lindenberg A, Millan MJ, Borgwardt S, Galderisi S, Bechdolf A, Pfennig A, Kessing LV, van Amelsvoort T, Nieman DH, Domschke K, Krebs MO, Koutsouleris N, McGuire P, Do KQ, Arango C. Fusar-Poli P, et al. JAMA Psychiatry. 2020 Jul 1;77(7):755-765. doi: 10.1001/jamapsychiatry.2019.4779. JAMA Psychiatry. 2020. PMID: 32159746
Effect of childhood physical abuse on social anxiety is mediated via reduced frontal lobe and amygdala-hippocampus complex volume in adult clinical high-risk subjects.
Salokangas RKR, Hietala J, Armio RL, Laurikainen H, From T, Borgwardt S, Riecher-Rössler A, Brambilla P, Bonivento C, Meisenzahl E, Schultze-Lutter F, Haidl T, Ruhrmann S, Upthegrove R, Wood SJ, Pantelis C, Kambeitz-Ilankovic L, Ruef A, Dwyer DB, Kambeitz J, Koutsouleris N. Salokangas RKR, et al. Schizophr Res. 2021 Jan;227:101-109. doi: 10.1016/j.schres.2020.05.041. Epub 2020 May 24. Schizophr Res. 2021. PMID: 32461085
Validation of the Bullying Scale for Adults - Results of the PRONIA-study.
Haidl TK, Schneider N, Dickmann K, Ruhrmann S, Kaiser N, Rosen M, Seves M, Lichtenstein T, Upthegrove R, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Rebekka L, Kambeitz J, Koutsouleris N, Schultze-Lutter F; PRONIA-consortium. Haidl TK, et al. J Psychiatr Res. 2020 Oct;129:88-97. doi: 10.1016/j.jpsychires.2020.04.004. Epub 2020 May 11. J Psychiatr Res. 2020. PMID: 32623026
The Psychopathology and Neuroanatomical Markers of Depression in Early Psychosis.
Upthegrove R, Lalousis P, Mallikarjun P, Chisholm K, Griffiths SL, Iqbal M, Pelton M, Reniers R, Stainton A, Rosen M, Ruef A, Dwyer DB, Surman M, Haidl T, Penzel N, Kambeitz-Llankovic L, Bertolino A, Brambilla P, Borgwardt S, Kambeitz J, Lencer R, Pantelis C, Ruhrmann S, Schultze-Lutter F, Salokangas RKR, Meisenzahl E, Wood SJ, Koutsouleris N; PRONIA Consortium. Upthegrove R, et al. Schizophr Bull. 2021 Jan 23;47(1):249-258. doi: 10.1093/schbul/sbaa094. Schizophr Bull. 2021. PMID: 32634220 Free PMC article. Clinical Trial.
Traces of Trauma: A Multivariate Pattern Analysis of Childhood Trauma, Brain Structure, and Clinical Phenotypes.
Popovic D, Ruef A, Dwyer DB, Antonucci LA, Eder J, Sanfelici R, Kambeitz-Ilankovic L, Oztuerk OF, Dong MS, Paul R, Paolini M, Hedderich D, Haidl T, Kambeitz J, Ruhrmann S, Chisholm K, Schultze-Lutter F, Falkai P, Pergola G, Blasi G, Bertolino A, Lencer R, Dannlowski U, Upthegrove R, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Koutsouleris N; PRONIA Consortium. Popovic D, et al. Biol Psychiatry. 2020 Dec 1;88(11):829-842. doi: 10.1016/j.biopsych.2020.05.020. Epub 2020 May 26. Biol Psychiatry. 2020. PMID: 32782139
Development of Proteomic Prediction Models for Transition to Psychotic Disorder in the Clinical High-Risk State and Psychotic Experiences in Adolescence.
Mongan D, Föcking M, Healy C, Susai SR, Heurich M, Wynne K, Nelson B, McGorry PD, Amminger GP, Nordentoft M, Krebs MO, Riecher-Rössler A, Bressan RA, Barrantes-Vidal N, Borgwardt S, Ruhrmann S, Sachs G, Pantelis C, van der Gaag M, de Haan L, Valmaggia L, Pollak TA, Kempton MJ, Rutten BPF, Whelan R, Cannon M, Zammit S, Cagney G, Cotter DR, McGuire P; European Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI) High Risk Study Group. Mongan D, et al. JAMA Psychiatry. 2021 Jan 1;78(1):77-90. doi: 10.1001/jamapsychiatry.2020.2459. JAMA Psychiatry. 2021. PMID: 32857162 Free PMC article.
Dysregulated Lipid Metabolism Precedes Onset of Psychosis.
Dickens AM, Sen P, Kempton MJ, Barrantes-Vidal N, Iyegbe C, Nordentoft M, Pollak T, Riecher-Rössler A, Ruhrmann S, Sachs G, Bressan R, Krebs MO, Amminger GP, de Haan L, van der Gaag M, Valmaggia L, Hyötyläinen T; EU-GEI High Risk Study Group; Orešič M, McGuire P. Dickens AM, et al. Biol Psychiatry. 2021 Feb 1;89(3):288-297. doi: 10.1016/j.biopsych.2020.07.012. Epub 2020 Jul 25. Biol Psychiatry. 2021. PMID: 32928501 Free article.
A multivariate neuromonitoring approach to neuroplasticity-based computerized cognitive training in recent onset psychosis.
Haas SS, Antonucci LA, Wenzel J, Ruef A, Biagianti B, Paolini M, Rauchmann BS, Weiske J, Kambeitz J, Borgwardt S, Brambilla P, Meisenzahl E, Salokangas RKR, Upthegrove R, Wood SJ, Koutsouleris N, Kambeitz-Ilankovic L. Haas SS, et al. Neuropsychopharmacology. 2021 Mar;46(4):828-835. doi: 10.1038/s41386-020-00877-4. Epub 2020 Oct 7. Neuropsychopharmacology. 2021. PMID: 33027802 Free PMC article.
Clinical, cognitive and neuroanatomical associations of serum NMDAR autoantibodies in people at clinical high risk for psychosis.
Pollak TA, Kempton MJ, Iyegbe C, Vincent A, Irani SR, Coutinho E, Menassa DA, Jacobson L, de Haan L, Ruhrmann S, Sachs G, Riecher-Rössler A, Krebs MO, Amminger P, Glenthøj B, Barrantes-Vidal N, van Os J, Rutten BPF, Bressan RA, van der Gaag M, Yolken R, Hotopf M, Valmaggia L, Stone J, David AS; EUGEI High-Risk Study; McGuire P. Pollak TA, et al. Mol Psychiatry. 2021 Jun;26(6):2590-2604. doi: 10.1038/s41380-020-00899-w. Epub 2020 Oct 19. Mol Psychiatry. 2021. PMID: 33077853 Free PMC article.
Pre-training inter-rater reliability of clinical instruments in an international psychosis research project.
Berendsen S, Kapitein P, Schirmbeck F, van Tricht MJ, McGuire P, Morgan C, Gayer-Anderson C, Kempton MJ, Valmaggia L, Quattrone D, di Forti M, van der Gaag M, Kirkbride JB, Jongsma HE, Jones PB, Parellada M, Arango C, Arrojo M, Bernardo M, Sanjuán J, Santos JL, Szöke A, Tortelli A, Llorca PM, Tarricone I, Tripoli G, Ferraro L, La Cascia C, Lasalvia A, Tosato S, Menezes PR, Del-Ben CM, Nelson B, Riecher-Rössler A, Bressan R, Barrantes-Vidal N, Krebs MO, Nordentoft M, Ruhrmann S, Sachs G, Rutten BPF, van Os J, Velthorst E, de Haan L; EU-GEI High Risk Study. Berendsen S, et al. Schizophr Res. 2021 Apr;230:104-107. doi: 10.1016/j.schres.2020.08.001. Epub 2020 Nov 24. Schizophr Res. 2021. PMID: 33243716 No abstract available.
Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression.
Koutsouleris N, Dwyer DB, Degenhardt F, Maj C, Urquijo-Castro MF, Sanfelici R, Popovic D, Oeztuerk O, Haas SS, Weiske J, Ruef A, Kambeitz-Ilankovic L, Antonucci LA, Neufang S, Schmidt-Kraepelin C, Ruhrmann S, Penzel N, Kambeitz J, Haidl TK, Rosen M, Chisholm K, Riecher-Rössler A, Egloff L, Schmidt A, Andreou C, Hietala J, Schirmer T, Romer G, Walger P, Franscini M, Traber-Walker N, Schimmelmann BG, Flückiger R, Michel C, Rössler W, Borisov O, Krawitz PM, Heekeren K, Buechler R, Pantelis C, Falkai P, Salokangas RKR, Lencer R, Bertolino A, Borgwardt S, Noethen M, Brambilla P, Wood SJ, Upthegrove R, Schultze-Lutter F, Theodoridou A, Meisenzahl E; PRONIA Consortium. Koutsouleris N, et al. JAMA Psychiatry. 2021 Feb 1;78(2):195-209. doi: 10.1001/jamapsychiatry.2020.3604. JAMA Psychiatry. 2021. PMID: 33263726 Free PMC article.
Basic Symptoms Are Associated With Age in Patients With a Clinical High-Risk State for Psychosis: Results From the PRONIA Study.
Walger H, Antonucci LA, Pigoni A, Upthegrove R, Salokangas RKR, Lencer R, Chisholm K, Riecher-Rössler A, Haidl T, Meisenzahl E, Rosen M, Ruhrmann S, Kambeitz J, Kambeitz-Ilankovic L, Falkai P, Ruef A, Hietala J, Pantelis C, Wood SJ, Brambilla P, Bertolino A, Borgwardt S, Koutsouleris N, Schultze-Lutter F. Walger H, et al. Front Psychiatry. 2020 Nov 17;11:552175. doi: 10.3389/fpsyt.2020.552175. eCollection 2020. Front Psychiatry. 2020. PMID: 33312133 Free PMC article.
General psychopathology links burden of recent life events and psychotic symptoms in a network approach.
Betz LT, Penzel N, Kambeitz-Ilankovic L, Rosen M, Chisholm K, Stainton A, Haidl TK, Wenzel J, Bertolino A, Borgwardt S, Brambilla P, Lencer R, Meisenzahl E, Ruhrmann S, Salokangas RKR, Schultze-Lutter F, Wood SJ, Upthegrove R, Koutsouleris N, Kambeitz J; PRONIA consortium. Betz LT, et al. NPJ Schizophr. 2020 Dec 15;6(1):40. doi: 10.1038/s41537-020-00129-w. NPJ Schizophr. 2020. PMID: 33319805 Free PMC article.
Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings.
Velthorst E, Mollon J, Murray RM, de Haan L, Germeys IM, Glahn DC, Arango C, van der Ven E, Di Forti M, Bernardo M, Guloksuz S, Delespaul P, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Santos JL, Jiménez-López E, Sanjuan J, Aguilar EJ, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Atbaşoğlu C, Saka MC, Üçok A, Alptekin K, Akdede B, Binbay T, Altınyazar V, Ulaş H, Yalınçetin B, Gümüş-Akay G, Beyaz BC, Soygür H, Cankurtaran EŞ, Kaymak SU, Maric NP, Mihaljevic MM, Petrovic SA, Mirjanic T, Del-Ben CM, Ferraro L, Gayer-Anderson C, Jones PB, Jongsma HE, Kirkbride JB, La Cascia C, Lasalvia A, Tosato S, Llorca PM, Menezes PR, Morgan C, Quattrone D, Menchetti M, Selten JP, Szöke A, Tarricone I, Tortelli A, McGuire P, Valmaggia L, Kempton MJ, van der Gaag M, Riecher-Rössler A, Bressan RA, Barrantes-Vidal N, Nelson B, McGorry P, Pantelis C, Krebs MO, Ruhrmann S, Sachs G, Rutten BPF, van Os J, Alizadeh BZ, van Amelsvoort T, Bartels-Velthuis AA, Bruggeman R, van Beveren NJ, Luykx JJ, Cahn W, Simons CJP, Kahn RS, Schirmbeck F, van Winkel R; EU-GEI High Risk Study; Reichenberg A. Velthorst E, et al. Mol Psychiatry. 2021 Aug;26(8):4529-4543. doi: 10.1038/s41380-020-00969-z. Epub 2021 Jan 7. Mol Psychiatry. 2021. PMID: 33414498
Heterogeneity and Classification of Recent Onset Psychosis and Depression: A Multimodal Machine Learning Approach.
Lalousis PA, Wood SJ, Schmaal L, Chisholm K, Griffiths SL, Reniers RLEP, Bertolino A, Borgwardt S, Brambilla P, Kambeitz J, Lencer R, Pantelis C, Ruhrmann S, Salokangas RKR, Schultze-Lutter F, Bonivento C, Dwyer D, Ferro A, Haidl T, Rosen M, Schmidt A, Meisenzahl E, Koutsouleris N, Upthegrove R; PRONIA Consortium. Lalousis PA, et al. Schizophr Bull. 2021 Jul 8;47(4):1130-1140. doi: 10.1093/schbul/sbaa185. Schizophr Bull. 2021. PMID: 33543752 Free PMC article.
Obsessive-Compulsive Symptoms and Other Symptoms of the At-risk Mental State for Psychosis: A Network Perspective.
Ong HL, Isvoranu AM, Schirmbeck F, McGuire P, Valmaggia L, Kempton MJ, van der Gaag M, Riecher-Rössler A, Bressan RA, Barrantes-Vidal N, Nelson B, Amminger GP, McGorry P, Pantelis C, Krebs MO, Nordentoft M, Glenthøj B, Ruhrmann S, Sachs G, Rutten BPF, van Os J, de Haan L, Borsboom D; EU-GEI High Risk Study. Ong HL, et al. Schizophr Bull. 2021 Jul 8;47(4):1018-1028. doi: 10.1093/schbul/sbaa187. Schizophr Bull. 2021. PMID: 33595089 Free PMC article.
Association between age of cannabis initiation and gray matter covariance networks in recent onset psychosis.
Penzel N, Antonucci LA, Betz LT, Sanfelici R, Weiske J, Pogarell O, Cumming P, Quednow BB, Howes O, Falkai P, Upthegrove R, Bertolino A, Borgwardt S, Brambilla P, Lencer R, Meisenzahl E, Rosen M, Haidl T, Kambeitz-Ilankovic L, Ruhrmann S, Salokangas RRK, Pantelis C, Wood SJ, Koutsouleris N, Kambeitz J; PRONIA Consortium. Penzel N, et al. Neuropsychopharmacology. 2021 Jul;46(8):1484-1493. doi: 10.1038/s41386-021-00977-9. Epub 2021 Mar 3. Neuropsychopharmacology. 2021. PMID: 33658653 Free PMC article.
Cognitive subtypes in recent onset psychosis: distinct neurobiological fingerprints?
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Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis.
ENIGMA Clinical High Risk for Psychosis Working Group; Jalbrzikowski M, Hayes RA, Wood SJ, Nordholm D, Zhou JH, Fusar-Poli P, Uhlhaas PJ, Takahashi T, Sugranyes G, Kwak YB, Mathalon DH, Katagiri N, Hooker CI, Smigielski L, Colibazzi T, Via E, Tang J, Koike S, Rasser PE, Michel C, Lebedeva I, Hegelstad WTV, de la Fuente-Sandoval C, Waltz JA, Mizrahi R, Corcoran CM, Resch F, Tamnes CK, Haas SS, Lemmers-Jansen ILJ, Agartz I, Allen P, Amminger GP, Andreassen OA, Atkinson K, Bachman P, Baeza I, Baldwin H, Bartholomeusz CF, Borgwardt S, Catalano S, Chee MWL, Chen X, Cho KIK, Cooper RE, Cropley VL, Dolz M, Ebdrup BH, Fortea A, Glenthøj LB, Glenthøj BY, de Haan L, Hamilton HK, Harris MA, Haut KM, He Y, Heekeren K, Heinz A, Hubl D, Hwang WJ, Kaess M, Kasai K, Kim M, Kindler J, Klaunig MJ, Koppel A, Kristensen TD, Kwon JS, Lawrie SM, Lee J, León-Ortiz P, Lin A, Loewy RL, Ma X, McGorry P, McGuire P, Mizuno M, Møller P, Moncada-Habib T, Muñoz-Samons D, Nelson B, Nemoto T, Nordentoft M, Omelchenko MA, Oppedal K, Ouyang L, Pantelis C, Pariente JC, Raghava JM, Reyes-Madrigal F, Roach BJ, Røssberg JI, Rössler W, Salisbury DF, Sasabayashi D, Schall U, Schiffman J, Schlagenhauf F, Schmidt A, Sørens… See abstract for full author list ➔ ENIGMA Clinical High Risk for Psychosis Working Group, et al. JAMA Psychiatry. 2021 Jul 1;78(7):753-766. doi: 10.1001/jamapsychiatry.2021.0638. JAMA Psychiatry. 2021. PMID: 33950164 Free PMC article.
Classification of first-episode psychosis using cortical thickness: A large multicenter MRI study.
Pigoni A, Dwyer D, Squarcina L, Borgwardt S, Crespo-Facorro B, Dazzan P, Smesny S, Spaniel F, Spalletta G, Sanfelici R, Antonucci LA, Reuf A, Oeztuerk OF, Schmidt A, Ciufolini S, Schönborn-Harrisberger F, Langbein K, Gussew A, Reichenbach JR, Zaytseva Y, Piras F, Delvecchio G, Bellani M, Ruggeri M, Lasalvia A, Tordesillas-Gutiérrez D, Ortiz V, Murray RM, Reis-Marques T, Di Forti M, Koutsouleris N, Brambilla P; ClassiFEP group. Pigoni A, et al. Eur Neuropsychopharmacol. 2021 Jun;47:34-47. doi: 10.1016/j.euroneuro.2021.04.002. Epub 2021 May 3. Eur Neuropsychopharmacol. 2021. PMID: 33957410
Multimodal prognosis of negative symptom severity in individuals at increased risk of developing psychosis.
Hauke DJ, Schmidt A, Studerus E, Andreou C, Riecher-Rössler A, Radua J, Kambeitz J, Ruef A, Dwyer DB, Kambeitz-Ilankovic L, Lichtenstein T, Sanfelici R, Penzel N, Haas SS, Antonucci LA, Lalousis PA, Chisholm K, Schultze-Lutter F, Ruhrmann S, Hietala J, Brambilla P, Koutsouleris N, Meisenzahl E, Pantelis C, Rosen M, Salokangas RKR, Upthegrove R, Wood SJ, Borgwardt S; PRONIA Group. Hauke DJ, et al. Transl Psychiatry. 2021 May 24;11(1):312. doi: 10.1038/s41398-021-01409-4. Transl Psychiatry. 2021. PMID: 34031362 Free PMC article.
Stress reactivity as a putative mechanism linking childhood trauma with clinical outcomes in individuals at ultra-high-risk for psychosis: Findings from the EU-GEI High Risk Study.
Paetzold I, Myin-Germeys I, Schick A, Nelson B, Velthorst E, Schirmbeck F; EU-GEI High Risk Study; van Os J, Morgan C, Hartmann J, van der Gaag M, de Haan L, Valmaggia L, McGuire P, Kempton M, Reininghaus U. Paetzold I, et al. Epidemiol Psychiatr Sci. 2021 May 28;30:e40. doi: 10.1017/S2045796021000251. Epidemiol Psychiatr Sci. 2021. PMID: 34044905 Free PMC article.
The non-specific nature of mental health and structural brain outcomes following childhood trauma.
Haidl TK, Hedderich DM, Rosen M, Kaiser N, Seves M, Lichtenstein T, Penzel N, Wenzel J, Kambeitz-Ilankovic L, Ruef A, Popovic D, Schultze-Lutter F, Chisholm K, Upthegrove R, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Ruhrmann S, Kambeitz J, Koutsouleris N. Haidl TK, et al. Psychol Med. 2023 Feb;53(3):1005-1014. doi: 10.1017/S0033291721002439. Epub 2021 Jul 6. Psychol Med. 2023. PMID: 34225834
Impact of Comorbid Affective Disorders on Longitudinal Clinical Outcomes in Individuals at Ultra-high Risk for Psychosis.
Schirmbeck F, van der Burg NC, Blankers M, Vermeulen JM, McGuire P, Valmaggia LR, Kempton MJ, van der Gaag M, Riecher-Rössler A, Bressan RA, Barrantes-Vidal N, Nelson B, Amminger GP, McGorry P, Pantelis C, Krebs MO, Ruhrmann S, Sachs G, Rutten BPF, van Os J, Nordentoft M, Glenthøj B; EU-GEI High Risk Study Group Authors; Fusar-Poli P, de Haan L. Schirmbeck F, et al. Schizophr Bull. 2022 Jan 21;48(1):100-110. doi: 10.1093/schbul/sbab088. Schizophr Bull. 2022. PMID: 34417795 Free PMC article.
Toward Generalizable and Transdiagnostic Tools for Psychosis Prediction: An Independent Validation and Improvement of the NAPLS-2 Risk Calculator in the Multisite PRONIA Cohort.
Koutsouleris N, Worthington M, Dwyer DB, Kambeitz-Ilankovic L, Sanfelici R, Fusar-Poli P, Rosen M, Ruhrmann S, Anticevic A, Addington J, Perkins DO, Bearden CE, Cornblatt BA, Cadenhead KS, Mathalon DH, McGlashan T, Seidman L, Tsuang M, Walker EF, Woods SW, Falkai P, Lencer R, Bertolino A, Kambeitz J, Schultze-Lutter F, Meisenzahl E, Salokangas RKR, Hietala J, Brambilla P, Upthegrove R, Borgwardt S, Wood S, Gur RE, McGuire P, Cannon TD. Koutsouleris N, et al. Biol Psychiatry. 2021 Nov 1;90(9):632-642. doi: 10.1016/j.biopsych.2021.06.023. Epub 2021 Jul 6. Biol Psychiatry. 2021. PMID: 34482951 Free PMC article.
Novel Gyrification Networks Reveal Links with Psychiatric Risk Factors in Early Illness.
Sanfelici R, Ruef A, Antonucci LA, Penzel N, Sotiras A, Dong MS, Urquijo-Castro M, Wenzel J, Kambeitz-Ilankovic L, Hettwer MD, Ruhrmann S, Chisholm K, Riecher-Rössler A, Falkai P, Pantelis C, Salokangas RKR, Lencer R, Bertolino A, Kambeitz J, Meisenzahl E, Borgwardt S, Brambilla P, Wood SJ, Upthegrove R, Schultze-Lutter F, Koutsouleris N, Dwyer DB; PRONIA Consortium. Sanfelici R, et al. Cereb Cortex. 2022 Apr 5;32(8):1625-1636. doi: 10.1093/cercor/bhab288. Cereb Cortex. 2022. PMID: 34519351 Free PMC article.
The clinical relevance of formal thought disorder in the early stages of psychosis: results from the PRONIA study.
Oeztuerk OF, Pigoni A, Wenzel J, Haas SS, Popovic D, Ruef A, Dwyer DB, Kambeitz-Ilankovic L, Ruhrmann S, Chisholm K, Lalousis P, Griffiths SL, Lichtenstein T, Rosen M, Kambeitz J, Schultze-Lutter F, Liddle P, Upthegrove R, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Falkai P, Antonucci LA, Koutsouleris N; PRONIA Consortium. Oeztuerk OF, et al. Eur Arch Psychiatry Clin Neurosci. 2022 Apr;272(3):403-413. doi: 10.1007/s00406-021-01327-y. Epub 2021 Sep 17. Eur Arch Psychiatry Clin Neurosci. 2022. PMID: 34535813 Free PMC article.
Physical and mental health impact of COVID-19 on children, adolescents, and their families: The Collaborative Outcomes study on Health and Functioning during Infection Times - Children and Adolescents (COH-FIT-C&A).
Solmi M, Estradé A, Thompson T, Agorastos A, Radua J, Cortese S, Dragioti E, Leisch F, Vancampfort D, Thygesen LC, Aschauer H, Schloegelhofer M, Akimova E, Schneeberger A, Huber CG, Hasler G, Conus P, Cuénod KQD, von Känel R, Arrondo G, Fusar-Poli P, Gorwood P, Llorca PM, Krebs MO, Scanferla E, Kishimoto T, Rabbani G, Skonieczna-Żydecka K, Brambilla P, Favaro A, Takamiya A, Zoccante L, Colizzi M, Bourgin J, Kamiński K, Moghadasin M, Seedat S, Matthews E, Wells J, Vassilopoulou E, Gadelha A, Su KP, Kwon JS, Kim M, Lee TY, Papsuev O, Manková D, Boscutti A, Gerunda C, Saccon D, Righi E, Monaco F, Croatto G, Cereda G, Demurtas J, Brondino N, Veronese N, Enrico P, Politi P, Ciappolino V, Pfennig A, Bechdolf A, Meyer-Lindenberg A, Kahl KG, Domschke K, Bauer M, Koutsouleris N, Winter S, Borgwardt S, Bitter I, Balazs J, Czobor P, Unoka Z, Mavridis D, Tsamakis K, Bozikas VP, Tunvirachaisakul C, Maes M, Rungnirundorn T, Supasitthumrong T, Haque A, Brunoni AR, Costardi CG, Schuch FB, Polanczyk G, Luiz JM, Fonseca L, Aparicio LV, Valvassori SS, Nordentoft M, Vendsborg P, Hoffmann SH, Sehli J, Sartorius N, Heuss S, Guinart D, Hamilton J, Kane J, Rubio J, Sand M, Koyanagi A, Solanes A, Andreu-B… See abstract for full author list ➔ Solmi M, et al. J Affect Disord. 2022 Feb 15;299:367-376. doi: 10.1016/j.jad.2021.09.090. Epub 2021 Oct 2. J Affect Disord. 2022. PMID: 34606810 Free PMC article.
The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international online survey targeting physical and mental health effects of the COVID-19 pandemic.
Solmi M, Estradé A, Thompson T, Agorastos A, Radua J, Cortese S, Dragioti E, Leisch F, Vancampfort D, Thygesen LC, Aschauer H, Schloegelhofer M, Akimova E, Schneeberger A, Huber CG, Hasler G, Conus P, Cuénod KQD, von Känel R, Arrondo G, Fusar-Poli P, Gorwood P, Llorca PM, Krebs MO, Scanferla E, Kishimoto T, Rabbani G, Skonieczna-Żydecka K, Brambilla P, Favaro A, Takamiya A, Zoccante L, Colizzi M, Bourgin J, Kamiński K, Moghadasin M, Seedat S, Matthews E, Wells J, Vassilopoulou E, Gadelha A, Su KP, Kwon JS, Kim M, Lee TY, Papsuev O, Manková D, Boscutti A, Gerunda C, Saccon D, Righi E, Monaco F, Croatto G, Cereda G, Demurtas J, Brondino N, Veronese N, Enrico P, Politi P, Ciappolino V, Pfennig A, Bechdolf A, Meyer-Lindenberg A, Kahl KG, Domschke K, Bauer M, Koutsouleris N, Winter S, Borgwardt S, Bitter I, Balazs J, Czobor P, Unoka Z, Mavridis D, Tsamakis K, Bozikas VP, Tunvirachaisakul C, Maes M, Rungnirundorn T, Supasitthumrong T, Haque A, Brunoni AR, Costardi CG, Schuch FB, Polanczyk G, Luiz JM, Fonseca L, Aparicio LV, Valvassori SS, Nordentoft M, Vendsborg P, Hoffmann SH, Sehli J, Sartorius N, Heuss S, Guinart D, Hamilton J, Kane J, Rubio J, Sand M, Koyanagi A, Solanes A, Andreu-B… See abstract for full author list ➔ Solmi M, et al. J Affect Disord. 2022 Feb 15;299:393-407. doi: 10.1016/j.jad.2021.07.048. Epub 2021 Jul 19. J Affect Disord. 2022. PMID: 34949568 Free PMC article.
Relationships between global functioning and neuropsychological predictors in subjects at high risk of psychosis or with a recent onset of depression.
Squarcina L, Kambeitz-Ilankovic L, Bonivento C, Prunas C, Oldani L, Wenzel J, Ruef A, Dwyer D, Ferro A, Borgwardt S, Kambeitz J, Lichtenstein TK, Meisenzahl E, Pantelis C, Rosen M, Upthegrove R, Antonucci LA, Bertolino A, Lencer R, Ruhrmann S, Salokangas RRK, Schultze-Lutter F, Chisholm K, Stainton A, Wood SJ, Koutsouleris N, Brambilla P; PRONIA consortium. Squarcina L, et al. World J Biol Psychiatry. 2022 Oct;23(8):573-581. doi: 10.1080/15622975.2021.2014955. Epub 2022 Jan 20. World J Biol Psychiatry. 2022. PMID: 35048791
Detailed clinical phenotyping and generalisability in prognostic models of functioning in at-risk populations.
Rosen M, Betz LT, Kaiser N, Penzel N, Dwyer D, Lichtenstein TK, Schultze-Lutter F, Kambeitz-Ilankovic L, Bertolino A, Borgwardt S, Brambilla P, Lencer R, Meisenzahl E, Pantelis C, Salokangas RKR, Upthegrove R, Wood S, Ruhrmann S, Koutsouleris N, Kambeitz J; PRONIA consortium. Rosen M, et al. Br J Psychiatry. 2022 Jun;220(6):318-321. doi: 10.1192/bjp.2021.141. Epub 2021 Oct 6. Br J Psychiatry. 2022. PMID: 35049486
Using combined environmental-clinical classification models to predict role functioning outcome in clinical high-risk states for psychosis and recent-onset depression.
Antonucci LA, Penzel N, Sanfelici R, Pigoni A, Kambeitz-Ilankovic L, Dwyer D, Ruef A, Sen Dong M, Öztürk ÖF, Chisholm K, Haidl T, Rosen M, Ferro A, Pergola G, Andriola I, Blasi G, Ruhrmann S, Schultze-Lutter F, Falkai P, Kambeitz J, Lencer R, Dannlowski U, Upthegrove R, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Bertolino A, Koutsouleris N; PRONIA Consortium. Antonucci LA, et al. Br J Psychiatry. 2022 Apr;220(4):229-245. doi: 10.1192/bjp.2022.16. Epub 2022 Feb 14. Br J Psychiatry. 2022. PMID: 35152923 Free article.
Pattern of predictive features of continued cannabis use in patients with recent-onset psychosis and clinical high-risk for psychosis.
Penzel N, Sanfelici R, Antonucci LA, Betz LT, Dwyer D, Ruef A, Cho KIK, Cumming P, Pogarell O, Howes O, Falkai P, Upthegrove R, Borgwardt S, Brambilla P, Lencer R, Meisenzahl E, Schultze-Lutter F, Rosen M, Lichtenstein T, Kambeitz-Ilankovic L, Ruhrmann S, Salokangas RKR, Pantelis C, Wood SJ, Quednow BB, Pergola G, Bertolino A, Koutsouleris N, Kambeitz J; PRONIA Consortium. Penzel N, et al. Schizophrenia (Heidelb). 2022 Mar 9;8(1):19. doi: 10.1038/s41537-022-00218-y. Schizophrenia (Heidelb). 2022. PMID: 35264631 Free PMC article.
Evidence of discontinuity between psychosis-risk and non-clinical samples in the neuroanatomical correlates of social function.
Haas SS, Doucet GE, Antoniades M, Modabbernia A, Corcoran CM, Kahn RS, Kambeitz J, Kambeitz-Ilankovic L, Borgwardt S, Brambilla P, Upthegrove R, Wood SJ, Salokangas RKR, Hietala J, Meisenzahl E, Koutsouleris N, Frangou S. Haas SS, et al. Schizophr Res Cogn. 2022 Apr 2;29:100252. doi: 10.1016/j.scog.2022.100252. eCollection 2022 Sep. Schizophr Res Cogn. 2022. PMID: 35391789 Free PMC article.
Clinical, Brain, and Multilevel Clustering in Early Psychosis and Affective Stages.
Dwyer DB, Buciuman MO, Ruef A, Kambeitz J, Sen Dong M, Stinson C, Kambeitz-Ilankovic L, Degenhardt F, Sanfelici R, Antonucci LA, Lalousis PA, Wenzel J, Urquijo-Castro MF, Popovic D, Oeztuerk OF, Haas SS, Weiske J, Hauke D, Neufang S, Schmidt-Kraepelin C, Ruhrmann S, Penzel N, Lichtenstein T, Rosen M, Chisholm K, Riecher-Rössler A, Egloff L, Schmidt A, Andreou C, Hietala J, Schirmer T, Romer G, Michel C, Rössler W, Maj C, Borisov O, Krawitz PM, Falkai P, Pantelis C, Lencer R, Bertolino A, Borgwardt S, Noethen M, Brambilla P, Schultze-Lutter F, Meisenzahl E, Wood SJ, Davatzikos C, Upthegrove R, Salokangas RKR, Koutsouleris N; PRONIA Consortium. Dwyer DB, et al. JAMA Psychiatry. 2022 Jul 1;79(7):677-689. doi: 10.1001/jamapsychiatry.2022.1163. JAMA Psychiatry. 2022. PMID: 35583903 Free PMC article.
Neurobiologically Based Stratification of Recent-Onset Depression and Psychosis: Identification of Two Distinct Transdiagnostic Phenotypes.
Lalousis PA, Schmaal L, Wood SJ, Reniers RLEP, Barnes NM, Chisholm K, Griffiths SL, Stainton A, Wen J, Hwang G, Davatzikos C, Wenzel J, Kambeitz-Ilankovic L, Andreou C, Bonivento C, Dannlowski U, Ferro A, Lichtenstein T, Riecher-Rössler A, Romer G, Rosen M, Bertolino A, Borgwardt S, Brambilla P, Kambeitz J, Lencer R, Pantelis C, Ruhrmann S, Salokangas RKR, Schultze-Lutter F, Schmidt A, Meisenzahl E, Koutsouleris N, Dwyer D, Upthegrove R; PRONIA Consortium. Lalousis PA, et al. Biol Psychiatry. 2022 Oct 1;92(7):552-562. doi: 10.1016/j.biopsych.2022.03.021. Epub 2022 Apr 12. Biol Psychiatry. 2022. PMID: 35717212 Free PMC article.
The Relationship Between Grey Matter Volume and Clinical and Functional Outcomes in People at Clinical High Risk for Psychosis.
Tognin S, Richter A, Kempton MJ, Modinos G, Antoniades M, Azis M, Allen P, Bossong MG, Perez J, Pantelis C, Nelson B, Amminger P, Riecher-Rössler A, Barrantes-Vidal N, Krebs MO, Glenthøj B, Ruhrmann S, Sachs G, Rutten BPF, de Haan L, van der Gaag M; EU-GEI High Risk Study Group; Valmaggia LR, McGuire P. Tognin S, et al. Schizophr Bull Open. 2022 Jun 20;3(1):sgac040. doi: 10.1093/schizbullopen/sgac040. eCollection 2022 Jan. Schizophr Bull Open. 2022. PMID: 35903803 Free PMC article.
Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited.
Koutsouleris N, Pantelis C, Velakoulis D, McGuire P, Dwyer DB, Urquijo-Castro MF, Paul R, Dong S, Popovic D, Oeztuerk O, Kambeitz J, Salokangas RKR, Hietala J, Bertolino A, Brambilla P, Upthegrove R, Wood SJ, Lencer R, Borgwardt S, Maj C, Nöthen M, Degenhardt F, Polyakova M, Mueller K, Villringer A, Danek A, Fassbender K, Fliessbach K, Jahn H, Kornhuber J, Landwehrmeyer B, Anderl-Straub S, Prudlo J, Synofzik M, Wiltfang J, Riedl L, Diehl-Schmid J, Otto M, Meisenzahl E, Falkai P, Schroeter ML; International FTD-Genetics Consortium (IFGC), the German Frontotemporal Lobar Degeneration (FTLD) Consortium, and the PRONIA Consortium. Koutsouleris N, et al. JAMA Psychiatry. 2022 Sep 1;79(9):907-919. doi: 10.1001/jamapsychiatry.2022.2075. JAMA Psychiatry. 2022. PMID: 35921104 Free PMC article.
The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis.
Schwarzer JM, Meyhoefer I, Antonucci LA, Kambeitz-Ilankovic L, Surmann M, Bienek O, Romer G, Dannlowski U, Hahn T, Korda A, Dwyer DB, Ruef A, Haas SS, Rosen M, Lichtenstein T, Ruhrmann S, Kambeitz J, Salokangas RKR, Pantelis C, Schultze-Lutter F, Meisenzahl E, Brambilla P, Bertolino A, Borgwardt S, Upthegrove R, Koutsouleris N, Lencer R; PRONIA Consortium. Schwarzer JM, et al. Neuropsychopharmacology. 2022 Nov;47(12):2051-2060. doi: 10.1038/s41386-022-01385-3. Epub 2022 Aug 18. Neuropsychopharmacology. 2022. PMID: 35982238 Free PMC article.
Validation of the Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) questionnaire for adults.
Solmi M, Thompson T, Estradé A, Agorastos A, Radua J, Cortese S, Dragioti E, Leisch F, Vancampfort D, Thygesen LC, Aschauer H, Schlögelhofer M, Aschauer E, Schneeberger A, Huber CG, Hasler G, Conus P, Do Cuénod KQ, von Känel R, Arrondo G, Fusar-Poli P, Gorwood P, Llorca PM, Krebs MO, Scanferla E, Kishimoto T, Rabbani G, Skonieczna-Żydecka K, Brambilla P, Favaro A, Takamiya A, Zoccante L, Colizzi M, Bourgin J, Kamiński K, Moghadasin M, Seedat S, Matthews E, Wells J, Vassilopoulou E, Gadelha A, Su KP, Kwon JS, Kim M, Lee TY, Papsuev O, Manková D, Boscutti A, Gerunda C, Saccon D, Righi E, Monaco F, Croatto G, Cereda G, Demurtas J, Brondino N, Veronese N, Enrico P, Politi P, Ciappolino V, Pfennig A, Bechdolf A, Meyer-Lindenberg A, Kahl KG, Domschke K, Bauer M, Koutsouleris N, Winter S, Borgwardt S, Bitter I, Balazs J, Czobor P, Unoka Z, Mavridis D, Tsamakis K, Bozikas VP, Tunvirachaisakul C, Maes M, Rungnirundorn T, Supasitthumrong T, Haque A, Brunoni AR, Costardi CG, Schuch FB, Polanczyk G, Luiz JM, Fonseca L, Aparicio LV, Valvassori SS, Nordentoft M, Vendsborg P, Hoffmann SH, Sehli J, Sartorius N, Heuss S, Guinart D, Hamilton J, Kane J, Rubio J, Sand M, Koyanagi A, Solanes A, Andreu… See abstract for full author list ➔ Solmi M, et al. J Affect Disord. 2023 Apr 1;326:249-261. doi: 10.1016/j.jad.2022.12.022. Epub 2022 Dec 28. J Affect Disord. 2023. PMID: 36586617 Free PMC article.
Influence of cannabis use on incidence of psychosis in people at clinical high risk.
Chester LA, Valmaggia LR, Kempton MJ, Chesney E, Oliver D, Hedges EP, Klatsa E, Stahl D, van der Gaag M, de Haan L, Nelson B, McGorry P, Amminger GP, Riecher-Rössler A, Studerus E, Bressan R, Barrantes-Vidal N, Krebs MO, Glenthøj B, Nordentoft M, Ruhrmann S, Sachs G, McGuire P; EU-GEI High Risk Study Group. Chester LA, et al. Psychiatry Clin Neurosci. 2023 Sep;77(9):469-477. doi: 10.1111/pcn.13555. Epub 2023 May 13. Psychiatry Clin Neurosci. 2023. PMID: 37070555 Free PMC article.
Structural and Functional Brain Patterns Predict Formal Thought Disorder's Severity and Its Persistence in Recent-Onset Psychosis: Results From the PRONIA Study.
Buciuman MO, Oeztuerk OF, Popovic D, Enrico P, Ruef A, Bieler N, Sarisik E, Weiske J, Dong MS, Dwyer DB, Kambeitz-Ilankovic L, Haas SS, Stainton A, Ruhrmann S, Chisholm K, Kambeitz J, Riecher-Rössler A, Upthegrove R, Schultze-Lutter F, Salokangas RKR, Hietala J, Pantelis C, Lencer R, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Falkai P, Antonucci LA, Bertolino A, Liddle P, Koutsouleris N; PRONIA Consortium. Buciuman MO, et al. Biol Psychiatry Cogn Neurosci Neuroimaging. 2023 Dec;8(12):1207-1217. doi: 10.1016/j.bpsc.2023.06.001. Epub 2023 Jun 19. Biol Psychiatry Cogn Neurosci Neuroimaging. 2023. PMID: 37343661 Free article.
Prevalence of cognitive impairments and strengths in the early course of psychosis and depression.
Stainton A, Chisholm K, Griffiths SL, Kambeitz-Ilankovic L, Wenzel J, Bonivento C, Brambilla P, Iqbal M, Lichtenstein TK, Rosen M, Antonucci LA, Maggioni E, Kambeitz J, Borgwardt S, Riecher-Rössler A, Andreou C, Schmidt A, Schultze-Lutter F, Meisenzahl E, Ruhrmann S, Salokangas RKR, Pantelis C, Lencer R, Romer G, Bertolino A, Upthegrove R, Koutsouleris N, Allott K, Wood SJ; PRONIA Consortium; PRONIA Consortium. Stainton A, et al. Psychol Med. 2023 Oct;53(13):5945-5957. doi: 10.1017/S0033291723001770. Epub 2023 Jul 6. Psychol Med. 2023. PMID: 37409883 Free PMC article.
The heterogeneity of attenuated and brief limited psychotic symptoms: association of contents with age, sex, country, religion, comorbidities, and functioning.
Theisen C, Rosen M, Meisenzahl E, Koutsouleris N, Lichtenstein T, Ruhrmann S, Kambeitz J, Kambeitz-Ilankovic L, Riecher-Rössler A, Chisholm K, Upthegrove R, Antonucci LA, Bertolino A, Pigoni A, Salokangas RKR, Pantelis C, Wood SJ, Lencer R, Falkai P, Hietala J, Brambilla P, Schmidt A, Andreou C, Borgwardt S, Osman N, Schultze-Lutter F. Theisen C, et al. Front Psychiatry. 2023 Jul 7;14:1209485. doi: 10.3389/fpsyt.2023.1209485. eCollection 2023. Front Psychiatry. 2023. PMID: 37484669 Free PMC article.
Transdiagnostic subgroups of cognitive impairment in early affective and psychotic illness.
Wenzel J, Badde L, Haas SS, Bonivento C, Van Rheenen TE, Antonucci LA, Ruef A, Penzel N, Rosen M, Lichtenstein T, Lalousis PA, Paolini M, Stainton A, Dannlowski U, Romer G, Brambilla P, Wood SJ, Upthegrove R, Borgwardt S, Meisenzahl E, Salokangas RKR, Pantelis C, Lencer R, Bertolino A, Kambeitz J, Koutsouleris N, Dwyer DB, Kambeitz-Ilankovic L; PRONIA consortium. Wenzel J, et al. Neuropsychopharmacology. 2024 Feb;49(3):573-583. doi: 10.1038/s41386-023-01729-7. Epub 2023 Sep 22. Neuropsychopharmacology. 2024. PMID: 37737273 Free PMC article.
Algorithmic fairness in precision psychiatry: analysis of prediction models in individuals at clinical high risk for psychosis.
Şahin D, Kambeitz-Ilankovic L, Wood S, Dwyer D, Upthegrove R, Salokangas R, Borgwardt S, Brambilla P, Meisenzahl E, Ruhrmann S, Schultze-Lutter F, Lencer R, Bertolino A, Pantelis C, Koutsouleris N, Kambeitz J; PRONIA Study Group. Şahin D, et al. Br J Psychiatry. 2024 Feb;224(2):55-65. doi: 10.1192/bjp.2023.141. Br J Psychiatry. 2024. PMID: 37936347
Distinct multimodal biological and functional profiles of symptom-based subgroups in recent-onset psychosis.
Koutsouleris N, Buciuman MO, Vetter CS, Weyer CFC, Zhutovsky P, Perdomo ST, Khuntia A, Milaneschi Y, Popovic D, Ruef A, Dwyer D, Chisholm K, Kambeitz L, Antonucci L, Ruhrmann S, Kambeitz J, Riecher-Rössler A, Upthegrove R, Salokangas R, Hietala J, Pantelis C, Lencer R, Meisenzahl E, Wood S, Brambilla P, Borgwardt S, Bertolino A, Falkai P. Koutsouleris N, et al. Res Sq [Preprint]. 2024 Mar 13:rs.3.rs-3949072. doi: 10.21203/rs.3.rs-3949072/v1. Res Sq. 2024. PMID: 38559014 Free PMC article. Preprint.
Anhedonia as a Potential Transdiagnostic Phenotype With Immune-Related Changes in Recent-Onset Mental Health Disorders.
Lalousis PA, Malaviya A, Khatibi A, Saberi M, Kambeitz-Ilankovic L, Haas SS, Wood SJ, Barnes NM, Rogers J, Chisholm K, Bertolino A, Borgwardt S, Brambilla P, Kambeitz J, Lencer R, Pantelis C, Ruhrmann S, Salokangas RKR, Schultze-Lutter F, Schmidt A, Meisenzahl E, Dwyer D, Koutsouleris N, Upthegrove R, Griffiths SL; PRONIA Consortium. Lalousis PA, et al. Biol Psychiatry. 2024 Oct 1;96(7):615-622. doi: 10.1016/j.biopsych.2024.05.019. Epub 2024 May 30. Biol Psychiatry. 2024. PMID: 38823495 Free article.
Global and risk-group stratified well-being and mental health during the COVID-19 pandemic in adults: Results from the international COH-FIT Study.
Solmi M, Thompson T, Estradé A, Agorastos A, Radua J, Cortese S, Dragioti E, Vancampfort D, Thygesen LC, Aschauer H, Schlögelhofer M, Aschauer E, Schneeberger A, Huber CG, Hasler G, Conus P, Cuénod KQD, von Känel R, Arrondo G, Fusar-Poli P, Gorwood P, Llorca PM, Krebs MO, Scanferla E, Kishimoto T, Rabbani G, Skonieczna-Żydecka K, Brambilla P, Favaro A, Takamiya A, Zoccante L, Colizzi M, Bourgin J, Kamiński K, Moghadasin M, Seedat S, Matthews E, Wells J, Vassilopoulou E, Gadelha A, Su KP, Kwon JS, Kim M, Lee TY, Papsuev O, Manková D, Boscutti A, Gerunda C, Saccon D, Righi E, Monaco F, Croatto G, Cereda G, Demurtas J, Brondino N, Veronese N, Enrico P, Politi P, Ciappolino V, Pfennig A, Bechdolf A, Meyer-Lindenberg A, Kahl KG, Domschke K, Bauer M, Koutsouleris N, Winter S, Borgwardt S, Bitter I, Balazs J, Czobor P, Unoka Z, Mavridis D, Tsamakis K, Bozikas VP, Tunvirachaisakul C, Maes M, Rungnirundorn T, Supasitthumrong T, Haque A, Brunoni AR, Costardi CG, Schuch FB, Polanczyk G, Luiz JM, Fonseca L, Aparicio LV, Valvassori SS, Nordentoft M, Vendsborg P, Hoffmann SH, Sehli J, Sartorius N, Heuss S, Guinart D, Hamilton J, Kane J, Rubio J, Sand M, Koyanagi A, Solanes A, Andreu-Bernabeu A,… See abstract for full author list ➔ Solmi M, et al. Psychiatry Res. 2024 Dec;342:115972. doi: 10.1016/j.psychres.2024.115972. Epub 2024 May 23. Psychiatry Res. 2024. PMID: 39305825 Free article.
Collaborative outcomes study on health and functioning during infection times (COH-FIT): Insights on modifiable and non-modifiable risk and protective factors for wellbeing and mental health during the COVID-19 pandemic from multivariable and network analyses.
Solmi M, Thompson T, Cortese S, Estradé A, Agorastos A, Radua J, Dragioti E, Vancampfort D, Thygesen LC, Aschauer H, Schlögelhofer M, Aschauer E, Schneeberger A, Huber CG, Hasler G, Conus P, Cuénod KQD, von Känel R, Arrondo G, Fusar-Poli P, Gorwood P, Llorca PM, Krebs MO, Scanferla E, Kishimoto T, Rabbani G, Skonieczna-Żydecka K, Brambilla P, Favaro A, Takamiya A, Zoccante L, Colizzi M, Bourgin J, Kamiński K, Moghadasin M, Seedat S, Matthews E, Wells J, Vassilopoulou E, Gadelha A, Su KP, Kwon JS, Kim M, Lee TY, Papsuev O, Manková D, Boscutti A, Gerunda C, Saccon D, Righi E, Monaco F, Croatto G, Cereda G, Demurtas J, Brondino N, Veronese N, Enrico P, Politi P, Ciappolino V, Pfennig A, Bechdolf A, Meyer-Lindenberg A, Kahl KG, Domschke K, Bauer M, Koutsouleris N, Winter S, Borgwardt S, Bitter I, Balazs J, Czobor P, Unoka Z, Mavridis D, Tsamakis K, Bozikas VP, Tunvirachaisakul C, Maes M, Rungnirundorn T, Supasitthumrong T, Haque A, Brunoni AR, Costardi CG, Schuch FB, Polanczyk G, Luiz JM, Fonseca L, Aparicio LV, Valvassori SS, Nordentoft M, Vendsborg P, Hoffmann SH, Sehli J, Sartorius N, Heuss S, Guinart D, Hamilton J, Kane J, Rubio J, Sand M, Koyanagi A, Solanes A, Andreu-Bernabeu A,… See abstract for full author list ➔ Solmi M, et al. Eur Neuropsychopharmacol. 2025 Jan;90:1-15. doi: 10.1016/j.euroneuro.2024.07.010. Epub 2024 Sep 27. Eur Neuropsychopharmacol. 2025. PMID: 39341043
BMIgap: a new tool to quantify transdiagnostic brain signatures of current and future weight.
Koutsouleris N, Khuntia AT, Popovic D, Sarisik E, Buciuman MO, Pedersen ML, Westlye LT, Andreassen O, Meyer-Lindenberg A, Kambeitz J, Salokangas R, Hietala J, Bertolino A, Borgwardt S, Brambilla P, Upthegrove R, Wood S, Lencer R, Meisenzahl E, Falkai P, Schwarz E, Wiegand A. Koutsouleris N, et al. Res Sq [Preprint]. 2024 Dec 11:rs.3.rs-5259910. doi: 10.21203/rs.3.rs-5259910/v1. Res Sq. 2024. Update in: Nat Ment Health. 2025;3(11):1395-1406. doi: 10.1038/s44220-025-00522-3. PMID: 39711565 Free PMC article. Updated. Preprint.
Disrupted Hierarchical Functional Brain Organization in Affective and Psychotic Disorders: Insights from Functional Brain Gradients.
Kambeitz J, Hacker H, Hoheisel L, Buciuman M, Böke A, Lichtenstein T, Rosen M, Haas S, Ruef A, Dwyer D, Brambilla P, Bonivento C, Upthegrove R, Wood S, Borgwardt S, Meisenzahl E, Ruhrmann S, Salokangas R, Dannlowski U, Koutsouleris N, Kambeitz-Ilankovic L, Lencer R. Kambeitz J, et al. Res Sq [Preprint]. 2025 Apr 17:rs.3.rs-6287335. doi: 10.21203/rs.3.rs-6287335/v1. Res Sq. 2025. Update in: Transl Psychiatry. 2026 Jul 29;16(1):384. doi: 10.1038/s41398-026-04206-z. PMID: 40321774 Free PMC article. Updated. Preprint.
Exploring the predictive value of structural covariance networks for the diagnosis of schizophrenia.
Vetter CS, Bender A, Dwyer DB, Montembeault M, Ruef A, Chisholm K, Kambeitz-Ilankovic L, Antonucci LA, Ruhrmann S, Kambeitz J, Rosen M, Lichtenstein T, Riecher-Rössler A, Upthegrove R, Salokangas RKR, Hietala J, Pantelis C, Lencer R, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Falkai P, Bertolino A, Koutsouleris N; PRONIA Consortium. Vetter CS, et al. Front Psychiatry. 2025 Jun 9;16:1570797. doi: 10.3389/fpsyt.2025.1570797. eCollection 2025. Front Psychiatry. 2025. PMID: 40551821 Free PMC article.
From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging-Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression.
Buciuman MO, Haas SS, Antonucci LA, Sarisik E, Khuntia A, Lichtenstein T, Rosen M, Kambeitz J, Pantelis C, Lencer R, Bertolino A, Brambilla P, Upthegrove R, Wood SJ, Falkai P, Riecher-Rössler A, Ruhrmann S, Schultze-Lutter F, Meisenzahl E, Hietala J, Salokangas RKR, Borgwardt S, Dwyer DB, Kambeitz-Ilankovic L, Koutsouleris N; PRONIA Consortium. Buciuman MO, et al. Biol Psychiatry. 2026 Apr 15;99(8):692-705. doi: 10.1016/j.biopsych.2025.07.003. Epub 2025 Jul 9. Biol Psychiatry. 2026. PMID: 40645362 Free article.
Decoding Psychosis Risk: Neuroanatomical Correlates of the NAPLS-2 Calculator in the PRONIA Cohort.
Neuner LM, Weyer C, Kambeitz-Ilankovic L, Korda A, Dwyer D, Antonucci LA, Kambeitz J, Upthegrove R, Salokangas RKR, Hietala J, Pantelis C, Lencer R, Wood SJ, Brambilla P, Borgwardt S, Bertolino A, Romer G, Meisenzahl E, Dannlowski U, Falkai P, Cannon TD, Koutsouleris N, Hahn L; PRONIA Consortium. Neuner LM, et al. Schizophr Bull. 2026 Jul 3;52(4):sbaf135. doi: 10.1093/schbul/sbaf135. Schizophr Bull. 2026. PMID: 40856416
Active treatment of affective disturbances may improve functional outcomes in patients in the early state of psychosis: Results of the PRONIA study.
Salokangas RKR, Wenzel J, From T, Ilonen T, Armio RL, Laurikainen H, Tuominen L, Walta M, Ruef A, Bonivento C, Dwyer D, Brambilla P, Wood S, Upthegrove R, Borgwardt S, Meisenzahl E, Rosen M, Lichtenstein T, Ruhrmann S, Pantelis C, Lencer R, Bertolino A, Schultze-Lutter F, Riecher A, Kambeitz J, Kambeitz-Ilankovic L, Koutsouleris N, Hietala J; PRONIA consortium. Salokangas RKR, et al. Eur Psychiatry. 2025 Oct 1;68(1):e151. doi: 10.1192/j.eurpsy.2025.10113. Eur Psychiatry. 2025. PMID: 41030061 Free PMC article.
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