Colecraft HM - Search Results

1

Targeted deubiquitination rescues distinct trafficking-deficient ion channelopathies.

Kanner SA, Shuja Z, Choudhury P, Jain A, Colecraft HM. Kanner SA, et al. Among authors: colecraft hm. Nat Methods. 2020 Dec;17(12):1245-1253. doi: 10.1038/s41592-020-00992-6. Epub 2020 Nov 9. Nat Methods. 2020. PMID: 33169015 Free PMC article.

2

Sculpting ion channel functional expression with engineered ubiquitin ligases.

Kanner SA, Morgenstern T, Colecraft HM. Kanner SA, et al. Among authors: colecraft hm. Elife. 2017 Dec 19;6:e29744. doi: 10.7554/eLife.29744. Elife. 2017. PMID: 29256394 Free PMC article.

3

Development of a High-Throughput Flow Cytometry Assay to Monitor Defective Trafficking and Rescue of Long QT2 Mutant hERG Channels.

Kanner SA, Jain A, Colecraft HM. Kanner SA, et al. Among authors: colecraft hm. Front Physiol. 2018 Apr 19;9:397. doi: 10.3389/fphys.2018.00397. eCollection 2018. Front Physiol. 2018. PMID: 29725305 Free PMC article.

4

Regulation of microdomain voltage-gated L-type calcium channels in cardiac health and disease.

Shuja Z, Colecraft HM. Shuja Z, et al. Among authors: colecraft hm. Curr Opin Physiol. 2018 Apr;2:13-18. doi: 10.1016/j.cophys.2017.12.005. Epub 2017 Dec 23. Curr Opin Physiol. 2018. PMID: 29963649 Free PMC article.

5

Engineering selectivity into RGK GTPase inhibition of voltage-dependent calcium channels.

Puckerin AA, Chang DD, Shuja Z, Choudhury P, Scholz J, Colecraft HM. Puckerin AA, et al. Among authors: colecraft hm. Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):12051-12056. doi: 10.1073/pnas.1811024115. Epub 2018 Nov 5. Proc Natl Acad Sci U S A. 2018. PMID: 30397133 Free PMC article.

6

Cardiac CaV1.2 channels require β subunits for β-adrenergic-mediated modulation but not trafficking.

Yang L, Katchman A, Kushner J, Kushnir A, Zakharov SI, Chen BX, Shuja Z, Subramanyam P, Liu G, Papa A, Roybal D, Pitt GS, Colecraft HM, Marx SO. Yang L, et al. Among authors: colecraft hm. J Clin Invest. 2019 Feb 1;129(2):647-658. doi: 10.1172/JCI123878. Epub 2019 Jan 7. J Clin Invest. 2019. PMID: 30422117 Free PMC article.

7

Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy.

Khanna R, Yu J, Yang X, Moutal A, Chefdeville A, Gokhale V, Shuja Z, Chew LA, Bellampalli SS, Luo S, François-Moutal L, Serafini MJ, Ha T, Perez-Miller S, Park KD, Patwardhan AM, Streicher JM, Colecraft HM, Khanna M. Khanna R, et al. Among authors: colecraft hm. Pain. 2019 Jul;160(7):1644-1661. doi: 10.1097/j.pain.0000000000001524. Pain. 2019. PMID: 30933958 Free PMC article.

8

Mechanism of adrenergic Ca_V1.2 stimulation revealed by proximity proteomics.

Liu G, Papa A, Katchman AN, Zakharov SI, Roybal D, Hennessey JA, Kushner J, Yang L, Chen BX, Kushnir A, Dangas K, Gygi SP, Pitt GS, Colecraft HM, Ben-Johny M, Kalocsay M, Marx SO. Liu G, et al. Among authors: colecraft hm. Nature. 2020 Jan;577(7792):695-700. doi: 10.1038/s41586-020-1947-z. Epub 2020 Jan 22. Nature. 2020. PMID: 31969708 Free PMC article.

9

The mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency.

Jenewein T, Kanner SA, Bauer D, Hertel B, Colecraft HM, Moroni A, Thiel G, Kauferstein S. Jenewein T, et al. Among authors: colecraft hm. Channels (Austin). 2020 Dec;14(1):163-174. doi: 10.1080/19336950.2020.1751522. Channels (Austin). 2020. PMID: 32253972 Free PMC article.

10

Controlling ion channel trafficking by targeted ubiquitination and deubiquitination.

Morgenstern TJ, Colecraft HM. Morgenstern TJ, et al. Among authors: colecraft hm. Methods Enzymol. 2021;654:139-167. doi: 10.1016/bs.mie.2021.03.007. Epub 2021 Apr 7. Methods Enzymol. 2021. PMID: 34120711

11

Controlling ion channel function with renewable recombinant antibodies.

Colecraft HM, Trimmer JS. Colecraft HM, et al. J Physiol. 2022 May;600(9):2023-2036. doi: 10.1113/JP282403. Epub 2022 Mar 17. J Physiol. 2022. PMID: 35238051 Free PMC article. Review.

12

Selective posttranslational inhibition of Ca_Vβ₁-associated voltage-dependent calcium channels with a functionalized nanobody.

Morgenstern TJ, Nirwan N, Hernández-Ochoa EO, Bibollet H, Choudhury P, Laloudakis YD, Ben Johny M, Bannister RA, Schneider MF, Minor DL Jr, Colecraft HM. Morgenstern TJ, et al. Among authors: colecraft hm. Nat Commun. 2022 Dec 9;13(1):7556. doi: 10.1038/s41467-022-35025-7. Nat Commun. 2022. PMID: 36494348 Free PMC article.

13

Perturbation of the host cell Ca²⁺ homeostasis and ER-mitochondria contact sites by the SARS-CoV-2 structural proteins E and M.

Poggio E, Vallese F, Hartel AJW, Morgenstern TJ, Kanner SA, Rauh O, Giamogante F, Barazzuol L, Shepard KL, Colecraft HM, Clarke OB, Brini M, Calì T. Poggio E, et al. Among authors: colecraft hm. Cell Death Dis. 2023 Apr 29;14(4):297. doi: 10.1038/s41419-023-05817-w. Cell Death Dis. 2023. PMID: 37120609 Free PMC article.

14

Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex.

Zou X, Shanmugam SK, Kanner SA, Sampson KJ, Kass RS, Colecraft HM. Zou X, et al. Among authors: colecraft hm. Elife. 2023 Aug 31;12:e83466. doi: 10.7554/eLife.83466. Elife. 2023. PMID: 37650513 Free PMC article.

15

Transfer RNA-mediated restoration of potassium current and electrical correction in premature termination long-QT syndrome hERG mutants.

Blomquist VG, Niu J, Choudhury P, Al Saneh A, Colecraft HM, Ahern CA. Blomquist VG, et al. Among authors: colecraft hm. Mol Ther Nucleic Acids. 2023 Sep 16;34:102032. doi: 10.1016/j.omtn.2023.102032. eCollection 2023 Dec 12. Mol Ther Nucleic Acids. 2023. PMID: 37842167 Free PMC article.

16

Bio-inspired voltage-dependent calcium channel blockers.

Yang T, He LL, Chen M, Fang K, Colecraft HM. Yang T, et al. Among authors: colecraft hm. Nat Commun. 2013;4:2540. doi: 10.1038/ncomms3540. Nat Commun. 2013. PMID: 24096474 Free PMC article.

17

Ion channel engineering: perspectives and strategies.

Subramanyam P, Colecraft HM. Subramanyam P, et al. Among authors: colecraft hm. J Mol Biol. 2015 Jan 16;427(1):190-204. doi: 10.1016/j.jmb.2014.09.001. Epub 2014 Sep 7. J Mol Biol. 2015. PMID: 25205552 Free PMC article. Review.

18

LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms.

Aromolaran AS, Subramanyam P, Chang DD, Kobertz WR, Colecraft HM. Aromolaran AS, et al. Among authors: colecraft hm. Cardiovasc Res. 2014 Dec 1;104(3):501-11. doi: 10.1093/cvr/cvu231. Epub 2014 Oct 24. Cardiovasc Res. 2014. PMID: 25344363 Free PMC article.

19

hERG 1a LQT2 C-terminus truncation mutants display hERG 1b-dependent dominant negative mechanisms.

Puckerin A, Aromolaran KA, Chang DD, Zukin RS, Colecraft HM, Boutjdir M, Aromolaran AS. Puckerin A, et al. Among authors: colecraft hm. Heart Rhythm. 2016 May;13(5):1121-1130. doi: 10.1016/j.hrthm.2016.01.012. Epub 2016 Jan 13. Heart Rhythm. 2016. PMID: 26775140

20

Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect.

Ortuño MJ, Robinson ST, Subramanyam P, Paone R, Huang YY, Guo XE, Colecraft HM, Mann JJ, Ducy P. Ortuño MJ, et al. Among authors: colecraft hm. Nat Med. 2016 Oct;22(10):1170-1179. doi: 10.1038/nm.4166. Epub 2016 Sep 5. Nat Med. 2016. PMID: 27595322 Free PMC article.

21

A light-gated potassium channel for sustained neuronal inhibition.

Alberio L, Locarno A, Saponaro A, Romano E, Bercier V, Albadri S, Simeoni F, Moleri S, Pelucchi S, Porro A, Marcello E, Barsotti N, Kukovetz K, Boender AJ, Contestabile A, Luo S, Moutal A, Ji Y, Romani G, Beltrame M, Del Bene F, Di Luca M, Khanna R, Colecraft HM, Pasqualetti M, Thiel G, Tonini R, Moroni A. Alberio L, et al. Among authors: colecraft hm. Nat Methods. 2018 Nov;15(11):969-976. doi: 10.1038/s41592-018-0186-9. Epub 2018 Oct 30. Nat Methods. 2018. PMID: 30377377 Free PMC article.

22

The 2019 FASEB Science Research Conference on Ion Channel Regulation: Molecules to Disease, July 7-12, 2019, Lisbon, Portugal.

Colecraft HM, Khanna R. Colecraft HM, et al. FASEB J. 2020 Apr;34(4):4828-4831. doi: 10.1096/fj.202000367. Epub 2020 Mar 11. FASEB J. 2020. PMID: 32157730 Free PMC article. No abstract available.

23

Targeted ubiquitination of sensory neuron calcium channels reduces the development of neuropathic pain.

Sun L, Tong CK, Morgenstern TJ, Zhou H, Yang G, Colecraft HM. Sun L, et al. Among authors: colecraft hm. Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2118129119. doi: 10.1073/pnas.2118129119. Epub 2022 May 13. Proc Natl Acad Sci U S A. 2022. PMID: 35561213 Free PMC article.

24

Rad regulation of Ca_V1.2 channels controls cardiac fight-or-flight response.

Papa A, Zakharov SI, Katchman AN, Kushner JS, Chen BX, Yang L, Liu G, Jimenez AS, Eisert RJ, Bradshaw GA, Dun W, Ali SR, Rodriques A, Zhou K, Topkara V, Yang M, Morrow JP, Tsai EJ, Karlin A, Wan E, Kalocsay M, Pitt GS, Colecraft HM, Ben-Johny M, Marx SO. Papa A, et al. Among authors: colecraft hm. Nat Cardiovasc Res. 2022 Nov;1(11):1022-1038. doi: 10.1038/s44161-022-00157-y. Epub 2022 Nov 14. Nat Cardiovasc Res. 2022. PMID: 36424916 Free PMC article.

25

Molecular mechanisms, and selective pharmacological rescue, of Rem-inhibited CaV1.2 channels in heart.

Xu X, Marx SO, Colecraft HM. Xu X, et al. Among authors: colecraft hm. Circ Res. 2010 Sep 3;107(5):620-30. doi: 10.1161/CIRCRESAHA.110.224717. Epub 2010 Jul 8. Circ Res. 2010. PMID: 20616312 Free PMC article.

26

Distinct RGK GTPases differentially use α1- and auxiliary β-binding-dependent mechanisms to inhibit CaV1.2/CaV2.2 channels.

Yang T, Puckerin A, Colecraft HM. Yang T, et al. Among authors: colecraft hm. PLoS One. 2012;7(5):e37079. doi: 10.1371/journal.pone.0037079. Epub 2012 May 10. PLoS One. 2012. PMID: 22590648 Free PMC article.

27

A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary Ca_Vβ subunits.

Morgenstern TJ, Park J, Fan QR, Colecraft HM. Morgenstern TJ, et al. Among authors: colecraft hm. Elife. 2019 Aug 12;8:e49253. doi: 10.7554/eLife.49253. Elife. 2019. PMID: 31403402 Free PMC article.

28

Designer genetically encoded voltage-dependent calcium channel inhibitors inspired by RGK GTPases.

Colecraft HM. Colecraft HM. J Physiol. 2020 May;598(9):1683-1693. doi: 10.1113/JP276544. Epub 2020 Apr 21. J Physiol. 2020. PMID: 32104913 Free PMC article. Review.

29

Adrenergic Ca_V1.2 Activation via Rad Phosphorylation Converges at α_1C I-II Loop.

Papa A, Kushner J, Hennessey JA, Katchman AN, Zakharov SI, Chen BX, Yang L, Lu R, Leong S, Diaz J, Liu G, Roybal D, Liao X, Del Rivero Morfin PJ, Colecraft HM, Pitt GS, Clarke O, Topkara V, Ben-Johny M, Marx SO. Papa A, et al. Among authors: colecraft hm. Circ Res. 2021 Jan 8;128(1):76-88. doi: 10.1161/CIRCRESAHA.120.317839. Epub 2020 Oct 22. Circ Res. 2021. PMID: 33086983 Free PMC article.

30

Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels.

Zou X, Wu X, Sampson KJ, Colecraft HM, Larsson HP, Kass RS. Zou X, et al. Among authors: colecraft hm. Front Physiol. 2022 Nov 23;13:902224. doi: 10.3389/fphys.2022.902224. eCollection 2022. Front Physiol. 2022. PMID: 36505078 Free PMC article.

31

Engineering proteins for custom inhibition of Ca(V) channels.

Xu X, Colecraft HM. Xu X, et al. Among authors: colecraft hm. Physiology (Bethesda). 2009 Aug;24:210-8. doi: 10.1152/physiol.00010.2009. Physiology (Bethesda). 2009. PMID: 19675352 Free PMC article. Review.

32

Similar molecular determinants on Rem mediate two distinct modes of inhibition of Ca_V1.2 channels.

Puckerin AA, Chang DD, Subramanyam P, Colecraft HM. Puckerin AA, et al. Among authors: colecraft hm. Channels (Austin). 2016 Sep 2;10(5):379-394. doi: 10.1080/19336950.2016.1180489. Epub 2016 Apr 26. Channels (Austin). 2016. PMID: 27115600 Free PMC article.

33

Rem, a member of the RGK GTPases, inhibits recombinant CaV1.2 channels using multiple mechanisms that require distinct conformations of the GTPase.

Yang T, Xu X, Kernan T, Wu V, Colecraft HM. Yang T, et al. Among authors: colecraft hm. J Physiol. 2010 May 15;588(Pt 10):1665-81. doi: 10.1113/jphysiol.2010.187203. Epub 2010 Mar 22. J Physiol. 2010. PMID: 20308247 Free PMC article.

34

Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing.

Subramanyam P, Chang DD, Fang K, Xie W, Marks AR, Colecraft HM. Subramanyam P, et al. Among authors: colecraft hm. Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15461-6. doi: 10.1073/pnas.1308161110. Epub 2013 Sep 3. Proc Natl Acad Sci U S A. 2013. PMID: 24003157 Free PMC article.

35

Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels.

Yang T, Hendrickson WA, Colecraft HM. Yang T, et al. Among authors: colecraft hm. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18213-8. doi: 10.1073/pnas.1420984111. Epub 2014 Dec 8. Proc Natl Acad Sci U S A. 2014. PMID: 25489088 Free PMC article.

36

Rad and Rem are non-canonical G-proteins with respect to the regulatory role of guanine nucleotide binding in Ca(V)1.2 channel regulation.

Chang DD, Colecraft HM. Chang DD, et al. Among authors: colecraft hm. J Physiol. 2015 Dec 1;593(23):5075-90. doi: 10.1113/JP270889. J Physiol. 2015. PMID: 26426338 Free PMC article.

37

Mitochondrial oxidative stress during cardiac lipid overload causes intracellular calcium leak and arrhythmia.

Joseph LC, Subramanyam P, Radlicz C, Trent CM, Iyer V, Colecraft HM, Morrow JP. Joseph LC, et al. Among authors: colecraft hm. Heart Rhythm. 2016 Aug;13(8):1699-706. doi: 10.1016/j.hrthm.2016.05.002. Epub 2016 May 3. Heart Rhythm. 2016. PMID: 27154230 Free PMC article.

38

Engineered calmodulins reveal the unexpected eminence of Ca2+ channel inactivation in controlling heart excitation.

Alseikhan BA, DeMaria CD, Colecraft HM, Yue DT. Alseikhan BA, et al. Among authors: colecraft hm. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):17185-90. doi: 10.1073/pnas.262372999. Epub 2002 Dec 16. Proc Natl Acad Sci U S A. 2002. PMID: 12486220 Free PMC article.

39

Membrane-associated guanylate kinase-like properties of beta-subunits required for modulation of voltage-dependent Ca2+ channels.

Takahashi SX, Miriyala J, Colecraft HM. Takahashi SX, et al. Among authors: colecraft hm. Proc Natl Acad Sci U S A. 2004 May 4;101(18):7193-8. doi: 10.1073/pnas.0306665101. Epub 2004 Apr 20. Proc Natl Acad Sci U S A. 2004. PMID: 15100405 Free PMC article.

40

Mechanism of auxiliary β-subunit-mediated membrane targeting of L-type (Ca(V)1.2) channels.

Fang K, Colecraft HM. Fang K, et al. Among authors: colecraft hm. J Physiol. 2011 Sep 15;589(Pt 18):4437-55. doi: 10.1113/jphysiol.2011.214247. Epub 2011 Jul 11. J Physiol. 2011. PMID: 21746784 Free PMC article.

41

Calmodulin regulation of TMEM16A and 16B Ca(2+)-activated chloride channels.

Yang T, Colecraft HM. Yang T, et al. Among authors: colecraft hm. Channels (Austin). 2016;10(1):38-44. doi: 10.1080/19336950.2015.1058455. Epub 2015 Jun 17. Channels (Austin). 2016. PMID: 26083059 Free PMC article. Review.

42

Aberrant Splicing Promotes Proteasomal Degradation of L-type Ca_V1.2 Calcium Channels by Competitive Binding for Ca_Vβ Subunits in Cardiac Hypertrophy.

Hu Z, Wang JW, Yu D, Soon JL, de Kleijn DP, Foo R, Liao P, Colecraft HM, Soong TW. Hu Z, et al. Among authors: colecraft hm. Sci Rep. 2016 Oct 12;6:35247. doi: 10.1038/srep35247. Sci Rep. 2016. PMID: 27731386 Free PMC article.

43

Proteolytic cleavage and PKA phosphorylation of α_1C subunit are not required for adrenergic regulation of Ca_V1.2 in the heart.

Katchman A, Yang L, Zakharov SI, Kushner J, Abrams J, Chen BX, Liu G, Pitt GS, Colecraft HM, Marx SO. Katchman A, et al. Among authors: colecraft hm. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9194-9199. doi: 10.1073/pnas.1706054114. Epub 2017 Aug 7. Proc Natl Acad Sci U S A. 2017. PMID: 28784807 Free PMC article.

44

Research Highlights: Biophysics of Calcium.

Colecraft HM. Colecraft HM. Biophys J. 2020 Oct 20;119(8):1472-1473. doi: 10.1016/j.bpj.2020.09.032. Epub 2020 Oct 7. Biophys J. 2020. PMID: 33031740 Free PMC article. No abstract available.

45

Genetically encoded molecules for inducibly inactivating CaV channels.

Yang T, Suhail Y, Dalton S, Kernan T, Colecraft HM. Yang T, et al. Among authors: colecraft hm. Nat Chem Biol. 2007 Dec;3(12):795-804. doi: 10.1038/nchembio.2007.42. Epub 2007 Oct 21. Nat Chem Biol. 2007. PMID: 17952065

46

BIN1 localizes the L-type calcium channel to cardiac T-tubules.

Hong TT, Smyth JW, Gao D, Chu KY, Vogan JM, Fong TS, Jensen BC, Colecraft HM, Shaw RM. Hong TT, et al. Among authors: colecraft hm. PLoS Biol. 2010 Feb 16;8(2):e1000312. doi: 10.1371/journal.pbio.1000312. PLoS Biol. 2010. PMID: 20169111 Free PMC article.

47

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes.

Hong TT, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM. Hong TT, et al. Heart Rhythm. 2012 May;9(5):812-20. doi: 10.1016/j.hrthm.2011.11.055. Epub 2011 Dec 2. Heart Rhythm. 2012. PMID: 22138472 Free PMC article.

48

Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes.

Joseph LC, Barca E, Subramanyam P, Komrowski M, Pajvani U, Colecraft HM, Hirano M, Morrow JP. Joseph LC, et al. Among authors: colecraft hm. PLoS One. 2016 Jan 12;11(1):e0145750. doi: 10.1371/journal.pone.0145750. eCollection 2016. PLoS One. 2016. PMID: 26756466 Free PMC article.

49

High-fat diet-dependent modulation of the delayed rectifier K(+) current in adult guinea pig atrial myocytes.

Aromolaran AS, Colecraft HM, Boutjdir M. Aromolaran AS, et al. Among authors: colecraft hm. Biochem Biophys Res Commun. 2016 Jun 3;474(3):554-559. doi: 10.1016/j.bbrc.2016.04.113. Epub 2016 Apr 26. Biochem Biophys Res Commun. 2016. PMID: 27130822

50

Structural mechanism of ligand activation in human calcium-sensing receptor.

Geng Y, Mosyak L, Kurinov I, Zuo H, Sturchler E, Cheng TC, Subramanyam P, Brown AP, Brennan SC, Mun HC, Bush M, Chen Y, Nguyen TX, Cao B, Chang DD, Quick M, Conigrave AD, Colecraft HM, McDonald P, Fan QR. Geng Y, et al. Among authors: colecraft hm. Elife. 2016 Jul 19;5:e13662. doi: 10.7554/eLife.13662. Elife. 2016. PMID: 27434672 Free PMC article.

51

Potassium channels in the heart: structure, function and regulation.

Grandi E, Sanguinetti MC, Bartos DC, Bers DM, Chen-Izu Y, Chiamvimonvat N, Colecraft HM, Delisle BP, Heijman J, Navedo MF, Noskov S, Proenza C, Vandenberg JI, Yarov-Yarovoy V. Grandi E, et al. Among authors: colecraft hm. J Physiol. 2017 Apr 1;595(7):2209-2228. doi: 10.1113/JP272864. Epub 2016 Nov 13. J Physiol. 2017. PMID: 27861921 Free PMC article. Review.

52

Cooperative and acute inhibition by multiple C-terminal motifs of L-type Ca²⁺ channels.

Liu N, Yang Y, Ge L, Liu M, Colecraft HM, Liu X. Liu N, et al. Among authors: colecraft hm. Elife. 2017 Jan 6;6:e21989. doi: 10.7554/eLife.21989. Elife. 2017. PMID: 28059704 Free PMC article.

53

Correction: Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes.

Joseph LC, Barca E, Subramanyam P, Komrowski M, Pajvani U, Colecraft HM, Hirano M, Morrow JP. Joseph LC, et al. Among authors: colecraft hm. PLoS One. 2017 Mar 20;12(3):e0174525. doi: 10.1371/journal.pone.0174525. eCollection 2017. PLoS One. 2017. PMID: 28319186 Free PMC article.

54

Inhibition of NADPH oxidase 2 (NOX2) prevents sepsis-induced cardiomyopathy by improving calcium handling and mitochondrial function.

Joseph LC, Kokkinaki D, Valenti MC, Kim GJ, Barca E, Tomar D, Hoffman NE, Subramanyam P, Colecraft HM, Hirano M, Ratner AJ, Madesh M, Drosatos K, Morrow JP. Joseph LC, et al. Among authors: colecraft hm. JCI Insight. 2017 Sep 7;2(17):e94248. doi: 10.1172/jci.insight.94248. eCollection 2017 Sep 7. JCI Insight. 2017. PMID: 28878116 Free PMC article.

55

Dietary Saturated Fat Promotes Arrhythmia by Activating NOX2 (NADPH Oxidase 2).

Joseph LC, Avula UMR, Wan EY, Reyes MV, Lakkadi KR, Subramanyam P, Nakanishi K, Homma S, Muchir A, Pajvani UB, Thorp EB, Reiken SR, Marks AR, Colecraft HM, Morrow JP. Joseph LC, et al. Among authors: colecraft hm. Circ Arrhythm Electrophysiol. 2019 Nov;12(11):e007573. doi: 10.1161/CIRCEP.119.007573. Epub 2019 Oct 31. Circ Arrhythm Electrophysiol. 2019. PMID: 31665913 Free PMC article.

56

Gating movements and ion permeation in HCN4 pacemaker channels.

Saponaro A, Bauer D, Giese MH, Swuec P, Porro A, Gasparri F, Sharifzadeh AS, Chaves-Sanjuan A, Alberio L, Parisi G, Cerutti G, Clarke OB, Hamacher K, Colecraft HM, Mancia F, Hendrickson WA, Siegelbaum SA, DiFrancesco D, Bolognesi M, Thiel G, Santoro B, Moroni A. Saponaro A, et al. Among authors: colecraft hm. Mol Cell. 2021 Jul 15;81(14):2929-2943.e6. doi: 10.1016/j.molcel.2021.05.033. Epub 2021 Jun 23. Mol Cell. 2021. PMID: 34166608 Free PMC article.

57

G-protein inhibition of N- and P/Q-type calcium channels: distinctive elementary mechanisms and their functional impact.

Colecraft HM, Brody DL, Yue DT. Colecraft HM, et al. J Neurosci. 2001 Feb 15;21(4):1137-47. doi: 10.1523/JNEUROSCI.21-04-01137.2001. J Neurosci. 2001. PMID: 11160384 Free PMC article.

58

Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells.

Colecraft HM, Alseikhan B, Takahashi SX, Chaudhuri D, Mittman S, Yegnasubramanian V, Alvania RS, Johns DC, Marbán E, Yue DT. Colecraft HM, et al. J Physiol. 2002 Jun 1;541(Pt 2):435-52. doi: 10.1113/jphysiol.2002.018515. J Physiol. 2002. PMID: 12042350 Free PMC article.

59

A single CaVbeta can reconstitute both trafficking and macroscopic conductance of voltage-dependent calcium channels.

Dalton S, Takahashi SX, Miriyala J, Colecraft HM. Dalton S, et al. Among authors: colecraft hm. J Physiol. 2005 Sep 15;567(Pt 3):757-69. doi: 10.1113/jphysiol.2005.093195. Epub 2005 Jul 14. J Physiol. 2005. PMID: 16020456 Free PMC article.

60

Rem inhibits skeletal muscle EC coupling by reducing the number of functional L-type Ca2+ channels.

Bannister RA, Colecraft HM, Beam KG. Bannister RA, et al. Among authors: colecraft hm. Biophys J. 2008 Apr 1;94(7):2631-8. doi: 10.1529/biophysj.107.116467. Epub 2008 Jan 11. Biophys J. 2008. PMID: 18192376 Free PMC article.

61

Role of CaVbeta subunits, and lack of functional reserve, in protein kinase A modulation of cardiac CaV1.2 channels.

Miriyala J, Nguyen T, Yue DT, Colecraft HM. Miriyala J, et al. Among authors: colecraft hm. Circ Res. 2008 Apr 11;102(7):e54-64. doi: 10.1161/CIRCRESAHA.108.171736. Epub 2008 Mar 20. Circ Res. 2008. PMID: 18356540

62

Regulation of voltage-dependent calcium channels by RGK proteins.

Yang T, Colecraft HM. Yang T, et al. Among authors: colecraft hm. Biochim Biophys Acta. 2013 Jul;1828(7):1644-54. doi: 10.1016/j.bbamem.2012.10.005. Epub 2012 Oct 10. Biochim Biophys Acta. 2013. PMID: 23063948 Free PMC article. Review.

63

Structure and selectivity in bestrophin ion channels.

Yang T, Liu Q, Kloss B, Bruni R, Kalathur RC, Guo Y, Kloppmann E, Rost B, Colecraft HM, Hendrickson WA. Yang T, et al. Among authors: colecraft hm. Science. 2014 Oct 17;346(6207):355-9. doi: 10.1126/science.1259723. Epub 2014 Sep 25. Science. 2014. PMID: 25324390 Free PMC article.

64

Regulation of Blood Pressure by Targeting Ca_V1.2-Galectin-1 Protein Interaction.

Hu Z, Li G, Wang JW, Chong SY, Yu D, Wang X, Soon JL, Liang MC, Wong YP, Huang N, Colecraft HM, Liao P, Soong TW. Hu Z, et al. Among authors: colecraft hm. Circulation. 2018 Oct 2;138(14):1431-1445. doi: 10.1161/CIRCULATIONAHA.117.031231. Circulation. 2018. PMID: 29650545 Free PMC article.

65

Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency.

González BJ, Zhao H, Niu J, Williams DJ, Lee J, Goulbourne CN, Xing Y, Wang Y, Oberholzer J, Blumenkrantz MH, Chen X, LeDuc CA, Chung WK, Colecraft HM, Gromada J, Shen Y, Goland RS, Leibel RL, Egli D. González BJ, et al. Among authors: colecraft hm. Commun Biol. 2022 Aug 2;5(1):779. doi: 10.1038/s42003-022-03696-z. Commun Biol. 2022. PMID: 35918471 Free PMC article.

66

Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors.

Gavin AC, Colecraft HM. Gavin AC, et al. Among authors: colecraft hm. Handb Exp Pharmacol. 2023;279:139-155. doi: 10.1007/164_2023_656. Handb Exp Pharmacol. 2023. PMID: 37306815 Review.

67

Molecular and functional identification of m1 muscarinic acetylcholine receptors in rat ventricular myocytes.

Sharma VK, Colecraft HM, Wang DX, Levey AI, Grigorenko EV, Yeh HH, Sheu SS. Sharma VK, et al. Among authors: colecraft hm. Circ Res. 1996 Jul;79(1):86-93. doi: 10.1161/01.res.79.1.86. Circ Res. 1996. PMID: 8925573

68

Differential occurrence of reluctant openings in G-protein-inhibited N- and P/Q-type calcium channels.

Colecraft HM, Patil PG, Yue DT. Colecraft HM, et al. J Gen Physiol. 2000 Feb;115(2):175-92. doi: 10.1085/jgp.115.2.175. J Gen Physiol. 2000. PMID: 10653895 Free PMC article.

69

Ca(2+) channel modulation by recombinant auxiliary beta subunits expressed in young adult heart cells.

Wei SK, Colecraft HM, DeMaria CD, Peterson BZ, Zhang R, Kohout TA, Rogers TB, Yue DT. Wei SK, et al. Among authors: colecraft hm. Circ Res. 2000 Feb 4;86(2):175-84. doi: 10.1161/01.res.86.2.175. Circ Res. 2000. PMID: 10666413

70

Reverse engineering the L-type Ca2+ channel alpha1c subunit in adult cardiac myocytes using novel adenoviral vectors.

Ganesan AN, O'Rourke B, Maack C, Colecraft H, Sidor A, Johns DC. Ganesan AN, et al. Biochem Biophys Res Commun. 2005 Apr 8;329(2):749-54. doi: 10.1016/j.bbrc.2005.02.015. Biochem Biophys Res Commun. 2005. PMID: 15737650 Free PMC article.

71

L-type calcium channel targeting and local signalling in cardiac myocytes.

Shaw RM, Colecraft HM. Shaw RM, et al. Among authors: colecraft hm. Cardiovasc Res. 2013 May 1;98(2):177-86. doi: 10.1093/cvr/cvt021. Epub 2013 Feb 14. Cardiovasc Res. 2013. PMID: 23417040 Free PMC article. Review.

72

Preface.

Minor DL, Colecraft HM. Minor DL, et al. Among authors: colecraft hm. Methods Enzymol. 2021;652:xv-xvi. doi: 10.1016/S0076-6879(21)00205-6. Methods Enzymol. 2021. PMID: 34059292 No abstract available.

73

Preface.

Minor DL Jr, Colecraft HM. Minor DL Jr, et al. Among authors: colecraft hm. Methods Enzymol. 2021;653:xv-xvi. doi: 10.1016/S0076-6879(21)00234-2. Methods Enzymol. 2021. PMID: 34099184 No abstract available.

74

Preface.

Minor DL Jr, Colecraft HM. Minor DL Jr, et al. Among authors: colecraft hm. Methods Enzymol. 2021;654:xvii-xviii. doi: 10.1016/S0076-6879(21)00249-4. Methods Enzymol. 2021. PMID: 34120727 No abstract available.

75

Primary culture of adult rat heart myocytes.

Xu X, Colecraft HM. Xu X, et al. Among authors: colecraft hm. J Vis Exp. 2009 Jun 16;(28):1308. doi: 10.3791/1308. J Vis Exp. 2009. PMID: 19532115 Free PMC article.

76

Distinctive modulatory effects of five human auxiliary beta2 subunit splice variants on L-type calcium channel gating.

Takahashi SX, Mittman S, Colecraft HM. Takahashi SX, et al. Among authors: colecraft hm. Biophys J. 2003 May;84(5):3007-21. doi: 10.1016/S0006-3495(03)70027-7. Biophys J. 2003. PMID: 12719232 Free PMC article.

77

Custom distinctions in the interaction of G-protein beta subunits with N-type (CaV2.2) versus P/Q-type (CaV2.1) calcium channels.

Agler HL, Evans J, Colecraft HM, Yue DT. Agler HL, et al. Among authors: colecraft hm. J Gen Physiol. 2003 Jun;121(6):495-510. doi: 10.1085/jgp.200208770. J Gen Physiol. 2003. PMID: 12771191 Free PMC article.

78

A CaVbeta SH3/guanylate kinase domain interaction regulates multiple properties of voltage-gated Ca2+ channels.

Takahashi SX, Miriyala J, Tay LH, Yue DT, Colecraft HM. Takahashi SX, et al. Among authors: colecraft hm. J Gen Physiol. 2005 Oct;126(4):365-77. doi: 10.1085/jgp.200509354. J Gen Physiol. 2005. PMID: 16186563 Free PMC article.

79

Signaling mechanisms underlying muscarinic receptor-mediated increase in contraction rate in cultured heart cells.

Colecraft HM, Egamino JP, Sharma VK, Sheu SS. Colecraft HM, et al. J Biol Chem. 1998 Nov 27;273(48):32158-66. doi: 10.1074/jbc.273.48.32158. J Biol Chem. 1998. PMID: 9822693 Free article.

80

G protein-gated inhibitory module of N-type (ca(v)2.2) ca2+ channels.

Agler HL, Evans J, Tay LH, Anderson MJ, Colecraft HM, Yue DT. Agler HL, et al. Among authors: colecraft hm. Neuron. 2005 Jun 16;46(6):891-904. doi: 10.1016/j.neuron.2005.05.011. Neuron. 2005. PMID: 15953418 Free article.

81

Does mammalian heart contain only the M2 muscarinic receptor subtype?

Sharma VK, Colecraft HM, Rubin LE, Sheu SS. Sharma VK, et al. Among authors: colecraft hm. Life Sci. 1997;60(13-14):1023-9. doi: 10.1016/s0024-3205(97)00043-x. Life Sci. 1997. PMID: 9121343 Free article.

82

David T. Yue: in memoriam.

Dick IE, Colecraft HM. Dick IE, et al. Among authors: colecraft hm. Neuron. 2015 Mar 18;85(6):1158-61. doi: 10.1016/j.neuron.2015.02.040. Neuron. 2015. PMID: 25961084 Free article. No abstract available.

83

Multiplex epigenome editing of MECP2 to rescue Rett syndrome neurons.

Qian J, Guan X, Xie B, Xu C, Niu J, Tang X, Li CH, Colecraft HM, Jaenisch R, Liu XS. Qian J, et al. Among authors: colecraft hm. Sci Transl Med. 2023 Jan 18;15(679):eadd4666. doi: 10.1126/scitranslmed.add4666. Epub 2023 Jan 18. Sci Transl Med. 2023. PMID: 36652535

84

Spatial patterning of gene expression using surface-immobilized recombinant adenovirus.

Pirone DM, Qi L, Colecraft H, Chen CS. Pirone DM, et al. Biomed Microdevices. 2008 Aug;10(4):561-6. doi: 10.1007/s10544-008-9166-7. Biomed Microdevices. 2008. PMID: 18246428

85

A membrane-associated phosphoswitch in Rad controls adrenergic regulation of cardiac calcium channels.

Papa A, Del Rivero Morfin PJ, Chen BX, Yang L, Katchman AN, Zakharov SI, Liu G, Bohnen MS, Zheng V, Katz M, Subramaniam S, Hirsch JA, Weiss S, Dascal N, Karlin A, Pitt GS, Colecraft HM, Ben-Johny M, Marx SO. Papa A, et al. Among authors: colecraft hm. J Clin Invest. 2024 Jan 16;134(5):e176943. doi: 10.1172/JCI176943. J Clin Invest. 2024. PMID: 38227371 Free PMC article.

86

A Genetically Encoded Actuator Selectively Boosts L-type Calcium Channels in Diverse Physiological Settings.

Del Rivero Morfin PJ, Chavez DS, Jayaraman S, Yang L, Kochiss AL, Colecraft HM, Liu XS, Marx SO, Rajadhyaksha AM, Ben-Johny M. Del Rivero Morfin PJ, et al. Among authors: colecraft hm. bioRxiv [Preprint]. 2023 Sep 23:2023.09.22.558856. doi: 10.1101/2023.09.22.558856. bioRxiv. 2023. PMID: 37790372 Free PMC article. Preprint.

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