Donnelley M - Search Results

1

Role for animal models in understanding essential fatty acid deficiency in cystic fibrosis.

Hryciw DH, Jackson CA, Shrestha N, Parsons D, Donnelley M, McAinch AJ. Hryciw DH, et al. Among authors: donnelley m. Cell Mol Life Sci. 2021 Dec;78(24):7991-7999. doi: 10.1007/s00018-021-04014-2. Epub 2021 Nov 5. Cell Mol Life Sci. 2021. PMID: 34741185 Free PMC article. Review.

2

In Vivo 4D X-Ray Dark-Field Lung Imaging in Mice.

How YY, Reyne N, Croughan MK, Cmielewski P, Batey D, Costello LF, Smith R, Ahlers JN, Cholewa M, Kolodziej M, Duerr J, Mall MA, Kitchen MJ, Asselin-Labat ML, Paganin DM, Donnelley M, Morgan KS. How YY, et al. Among authors: donnelley m. IEEE Trans Med Imaging. 2026 Jan;45(1):269-280. doi: 10.1109/TMI.2025.3595666. IEEE Trans Med Imaging. 2026. PMID: 40758499

3

High-resolution visualization of airspace structures in intact mice via synchrotron phase-contrast X-ray imaging (PCXI).

Parsons DW, Morgan K, Donnelley M, Fouras A, Crosbie J, Williams I, Boucher RC, Uesugi K, Yagi N, Siu KK. Parsons DW, et al. Among authors: donnelley m. J Anat. 2008 Aug;213(2):217-27. doi: 10.1111/j.1469-7580.2008.00950.x. J Anat. 2008. PMID: 19172736 Free PMC article.

4

Real-time non-invasive detection of inhalable particulates delivered into live mouse airways.

Donnelley M, Morgan KS, Fouras A, Skinner W, Uesugi K, Yagi N, Siu KK, Parsons DW. Donnelley M, et al. J Synchrotron Radiat. 2009 Jul;16(Pt 4):553-61. doi: 10.1107/S0909049509012618. Epub 2009 May 9. J Synchrotron Radiat. 2009. PMID: 19535871

5

A new technique to examine individual pollutant particle and fibre deposition and transit behaviour in live mouse trachea.

Donnelley M, Siu KK, Morgan KS, Skinner W, Suzuki Y, Takeuchi A, Uesugi K, Yagi N, Parsons DW. Donnelley M, et al. J Synchrotron Radiat. 2010 Nov;17(6):719-29. doi: 10.1107/S0909049510028451. Epub 2010 Sep 3. J Synchrotron Radiat. 2010. PMID: 20975216

6

Synchrotron phase-contrast X-ray imaging reveals fluid dosing dynamics for gene transfer into mouse airways.

Donnelley M, Siu KK, Jamison RA, Parsons DW. Donnelley M, et al. Gene Ther. 2012 Jan;19(1):8-14. doi: 10.1038/gt.2011.80. Epub 2011 Jun 9. Gene Ther. 2012. PMID: 21654825

7

Dry deposition of pollutant and marker particles onto live mouse airway surfaces enhances monitoring of individual particle mucociliary transit behaviour.

Donnelley M, Morgan KS, Siu KK, Parsons DW. Donnelley M, et al. J Synchrotron Radiat. 2012 Jul;19(Pt 4):551-8. doi: 10.1107/S0909049512018250. Epub 2012 May 9. J Synchrotron Radiat. 2012. PMID: 22713889

8

Variability of in vivo fluid dose distribution in mouse airways is visualized by high-speed synchrotron X-ray imaging.

Donnelley M, Morgan KS, Siu KK, Parsons DW. Donnelley M, et al. J Aerosol Med Pulm Drug Deliv. 2013 Oct;26(5):307-16. doi: 10.1089/jamp.2012.1007. Epub 2013 Jan 8. J Aerosol Med Pulm Drug Deliv. 2013. PMID: 23298238

9

Measuring airway surface liquid depth in ex vivo mouse airways by x-ray imaging for the assessment of cystic fibrosis airway therapies.

Morgan KS, Donnelley M, Paganin DM, Fouras A, Yagi N, Suzuki Y, Takeuchi A, Uesugi K, Boucher RC, Parsons DW, Siu KK. Morgan KS, et al. Among authors: donnelley m. PLoS One. 2013;8(1):e55822. doi: 10.1371/journal.pone.0055822. Epub 2013 Jan 30. PLoS One. 2013. PMID: 23383288 Free PMC article.

10

Airway gene transfer in a non-human primate: lentiviral gene expression in marmoset lungs.

Farrow N, Miller D, Cmielewski P, Donnelley M, Bright R, Parsons DW. Farrow N, et al. Among authors: donnelley m. Sci Rep. 2013;3:1287. doi: 10.1038/srep01287. Sci Rep. 2013. PMID: 23412644 Free PMC article.

11

Non-invasive airway health assessment: synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo.

Donnelley M, Morgan KS, Siu KK, Farrow NR, Stahr CS, Boucher RC, Fouras A, Parsons DW. Donnelley M, et al. Sci Rep. 2014 Jan 14;4:3689. doi: 10.1038/srep03689. Sci Rep. 2014. PMID: 24418935 Free PMC article.

12

Tracking extended mucociliary transport activity of individual deposited particles: longitudinal synchrotron X-ray imaging in live mice.

Donnelley M, Morgan KS, Siu KK, Fouras A, Farrow NR, Carnibella RP, Parsons DW. Donnelley M, et al. J Synchrotron Radiat. 2014 Jul;21(Pt 4):768-73. doi: 10.1107/S160057751400856X. Epub 2014 May 14. J Synchrotron Radiat. 2014. PMID: 24971973

13

In vivo X-ray imaging reveals improved airway surface hydration after a therapy designed for cystic fibrosis.

Morgan KS, Donnelley M, Farrow N, Fouras A, Yagi N, Suzuki Y, Takeuchi A, Uesugi K, Boucher RC, Siu KK, Parsons DW. Morgan KS, et al. Among authors: donnelley m. Am J Respir Crit Care Med. 2014 Aug 15;190(4):469-71. doi: 10.1164/rccm.201405-0855LE. Am J Respir Crit Care Med. 2014. PMID: 25127306 Free PMC article. No abstract available.

14

Long-term therapeutic and reporter gene expression in lentiviral vector treated cystic fibrosis mice.

Cmielewski P, Donnelley M, Parsons DW. Cmielewski P, et al. Among authors: donnelley m. J Gene Med. 2014 Sep-Oct;16(9-10):291-9. doi: 10.1002/jgm.2778. J Gene Med. 2014. PMID: 25130650

15

Transduction of ferret airway epithelia using a pre-treatment and lentiviral gene vector.

Cmielewski P, Farrow N, Donnelley M, McIntyre C, Penny-Dimri J, Kuchel T, Parsons D. Cmielewski P, et al. Among authors: donnelley m. BMC Pulm Med. 2014 Nov 21;14:183. doi: 10.1186/1471-2466-14-183. BMC Pulm Med. 2014. PMID: 25413892 Free PMC article.

16

Live small-animal X-ray lung velocimetry and lung micro-tomography at the Australian Synchrotron Imaging and Medical Beamline.

Murrie RP, Morgan KS, Maksimenko A, Fouras A, Paganin DM, Hall C, Siu KK, Parsons DW, Donnelley M. Murrie RP, et al. Among authors: donnelley m. J Synchrotron Radiat. 2015 Jul;22(4):1049-55. doi: 10.1107/S1600577515006001. Epub 2015 Jun 6. J Synchrotron Radiat. 2015. PMID: 26134810

17

Quantification of heterogeneity in lung disease with image-based pulmonary function testing.

Stahr CS, Samarage CR, Donnelley M, Farrow N, Morgan KS, Zosky G, Boucher RC, Siu KK, Mall MA, Parsons DW, Dubsky S, Fouras A. Stahr CS, et al. Among authors: donnelley m. Sci Rep. 2016 Jul 27;6:29438. doi: 10.1038/srep29438. Sci Rep. 2016. PMID: 27461961 Free PMC article.

18

Challenges of up-scaling lentivirus production and processing.

McCarron A, Donnelley M, McIntyre C, Parsons D. McCarron A, et al. Among authors: donnelley m. J Biotechnol. 2016 Dec 20;240:23-30. doi: 10.1016/j.jbiotec.2016.10.016. Epub 2016 Oct 18. J Biotechnol. 2016. PMID: 27769802 Review.

19

High-resolution mucociliary transport measurement in live excised large animal trachea using synchrotron X-ray imaging.

Donnelley M, Morgan KS, Awadalla M, Farrow NR, Hall C, Parsons DW. Donnelley M, et al. Respir Res. 2017 May 16;18(1):95. doi: 10.1186/s12931-017-0573-2. Respir Res. 2017. PMID: 28511651 Free PMC article.

20

Role of Basal Cells in Producing Persistent Lentivirus-Mediated Airway Gene Expression.

Farrow N, Donnelley M, Cmielewski P, Roscioli E, Rout-Pitt N, McIntyre C, Bertoncello I, Parsons DW. Farrow N, et al. Among authors: donnelley m. Hum Gene Ther. 2018 Jun;29(6):653-662. doi: 10.1089/hum.2017.059. Epub 2018 Jan 3. Hum Gene Ther. 2018. PMID: 29179571

21

Gene therapy for Cystic Fibrosis: Improved delivery techniques and conditioning with lysophosphatidylcholine enhance lentiviral gene transfer in mouse lung airways.

Cmielewski P, Farrow N, Devereux S, Parsons D, Donnelley M. Cmielewski P, et al. Among authors: donnelley m. Exp Lung Res. 2017 Nov-Dec;43(9-10):426-433. doi: 10.1080/01902148.2017.1395931. Epub 2017 Dec 13. Exp Lung Res. 2017. PMID: 29236544 Free article.

22

Airway disease phenotypes in animal models of cystic fibrosis.

McCarron A, Donnelley M, Parsons D. McCarron A, et al. Among authors: donnelley m. Respir Res. 2018 Apr 2;19(1):54. doi: 10.1186/s12931-018-0750-y. Respir Res. 2018. PMID: 29609604 Free PMC article. Review.

23

Epithelial disruption: a new paradigm enabling human airway stem cell transplantation.

Farrow N, Cmielewski P, Donnelley M, Rout-Pitt N, Moodley Y, Bertoncello I, Parsons D. Farrow N, et al. Among authors: donnelley m. Stem Cell Res Ther. 2018 Jun 13;9(1):153. doi: 10.1186/s13287-018-0911-4. Stem Cell Res Ther. 2018. PMID: 29895311 Free PMC article.

24

Lobe-Specific Gene Vector Delivery to Rat Lungs Using a Miniature Bronchoscope.

McIntyre C, Donnelley M, Rout-Pitt N, Parsons D. McIntyre C, et al. Among authors: donnelley m. Hum Gene Ther Methods. 2018 Oct;29(5):228-235. doi: 10.1089/hgtb.2018.050. Epub 2018 Aug 10. Hum Gene Ther Methods. 2018. PMID: 29993287

25

Epithelial mesenchymal transition (EMT): a universal process in lung diseases with implications for cystic fibrosis pathophysiology.

Rout-Pitt N, Farrow N, Parsons D, Donnelley M. Rout-Pitt N, et al. Among authors: donnelley m. Respir Res. 2018 Jul 18;19(1):136. doi: 10.1186/s12931-018-0834-8. Respir Res. 2018. PMID: 30021582 Free PMC article. Review.

26

Gene Therapy for Cystic Fibrosis Lung Disease: Overcoming the Barriers to Translation to the Clinic.

Donnelley M, Parsons DW. Donnelley M, et al. Front Pharmacol. 2018 Nov 27;9:1381. doi: 10.3389/fphar.2018.01381. eCollection 2018. Front Pharmacol. 2018. PMID: 30538635 Free PMC article.

27

Backprojection Wiener deconvolution for computed tomographic reconstruction.

Wang Z, Cai J, Guo W, Donnelley M, Parsons D, Lee I. Wang Z, et al. Among authors: donnelley m. PLoS One. 2018 Dec 18;13(12):e0207907. doi: 10.1371/journal.pone.0207907. eCollection 2018. PLoS One. 2018. PMID: 30562345 Free PMC article.

28

Live-pig-airway surface imaging and whole-pig CT at the Australian Synchrotron Imaging and Medical Beamline.

Donnelley M, Morgan KS, Gradl R, Klein M, Hausermann D, Hall C, Maksimenko A, Parsons DW. Donnelley M, et al. J Synchrotron Radiat. 2019 Jan 1;26(Pt 1):175-183. doi: 10.1107/S1600577518014133. Epub 2019 Jan 1. J Synchrotron Radiat. 2019. PMID: 30655483

29

Transient Lentiviral Vector Production Using a Packed-Bed Bioreactor System.

McCarron A, Donnelley M, McIntyre C, Parsons D. McCarron A, et al. Among authors: donnelley m. Hum Gene Ther Methods. 2019 Jun;30(3):93-101. doi: 10.1089/hgtb.2019.038. Epub 2019 Jun 5. Hum Gene Ther Methods. 2019. PMID: 31084376

30

In Vitro, in Vivo, and Spectroscopic Assessment of Lead Exposure Reduction via Ingestion and Inhalation Pathways Using Phosphate and Iron Amendments.

Kastury F, Smith E, Doelsch E, Lombi E, Donnelley M, Cmielewski PL, Parsons DW, Scheckel KG, Paterson D, de Jonge MD, Herde C, Juhasz AL. Kastury F, et al. Among authors: donnelley m. Environ Sci Technol. 2019 Sep 3;53(17):10329-10341. doi: 10.1021/acs.est.9b02448. Epub 2019 Aug 13. Environ Sci Technol. 2019. PMID: 31356748 Free PMC article.

31

Particle coating alters mucociliary transit in excised rat trachea: A synchrotron X-ray imaging study.

Gardner M, McCarron A, Morgan K, Parsons D, Donnelley M. Gardner M, et al. Among authors: donnelley m. Sci Rep. 2019 Jul 29;9(1):10983. doi: 10.1038/s41598-019-47465-1. Sci Rep. 2019. PMID: 31358851 Free PMC article.

32

Large-scale production of lentiviral vectors using multilayer cell factories.

Rout-Pitt N, McCarron A, McIntyre C, Parsons D, Donnelley M. Rout-Pitt N, et al. Among authors: donnelley m. J Biol Methods. 2018 Apr 10;5(2):e90. doi: 10.14440/jbm.2018.236. eCollection 2018. J Biol Methods. 2018. PMID: 31453241 Free PMC article.

33

Dynamics of Lead Bioavailability and Speciation in Indoor Dust and X-ray Spectroscopic Investigation of the Link between Ingestion and Inhalation Pathways.

Kastury F, Smith E, Lombi E, Donnelley MW, Cmielewski PL, Parsons DW, Noerpel M, Scheckel KG, Kingston AM, Myers GR, Paterson D, de Jonge MD, Juhasz AL. Kastury F, et al. Among authors: donnelley mw. Environ Sci Technol. 2019 Oct 1;53(19):11486-11495. doi: 10.1021/acs.est.9b03249. Epub 2019 Sep 11. Environ Sci Technol. 2019. PMID: 31460750 Free PMC article.

34

Methods for dynamic synchrotron X-ray respiratory imaging in live animals.

Morgan KS, Parsons D, Cmielewski P, McCarron A, Gradl R, Farrow N, Siu K, Takeuchi A, Suzuki Y, Uesugi K, Uesugi M, Yagi N, Hall C, Klein M, Maksimenko A, Stevenson A, Hausermann D, Dierolf M, Pfeiffer F, Donnelley M. Morgan KS, et al. Among authors: donnelley m. J Synchrotron Radiat. 2020 Jan 1;27(Pt 1):164-175. doi: 10.1107/S1600577519014863. Epub 2020 Jan 1. J Synchrotron Radiat. 2020. PMID: 31868749 Free PMC article.

35

Real-time in vivo imaging of regional lung function in a mouse model of cystic fibrosis on a laboratory X-ray source.

Murrie RP, Werdiger F, Donnelley M, Lin YW, Carnibella RP, Samarage CR, Pinar I, Preissner M, Wang J, Li J, Morgan KS, Parsons DW, Dubsky S, Fouras A. Murrie RP, et al. Among authors: donnelley m. Sci Rep. 2020 Jan 16;10(1):447. doi: 10.1038/s41598-019-57376-w. Sci Rep. 2020. PMID: 31949224 Free PMC article.

36

Towards automated in vivo tracheal mucociliary transport measurement: Detecting and tracking particle movement in synchrotron phase-contrast x-ray images.

Gardner M, Parsons D, Morgan K, McCarron A, Cmielewski P, Gradl R, Donnelley M. Gardner M, et al. Among authors: donnelley m. Phys Med Biol. 2020 Jul 23;65(14):145012. doi: 10.1088/1361-6560/ab7509. Phys Med Biol. 2020. PMID: 32045895

37

Phenotypic Characterization and Comparison of Cystic Fibrosis Rat Models Generated Using CRISPR/Cas9 Gene Editing.

McCarron A, Cmielewski P, Reyne N, McIntyre C, Finnie J, Craig F, Rout-Pitt N, Delhove J, Schjenken JE, Chan HY, Boog B, Knight E, Gilmore RC, O'Neal WK, Boucher RC, Parsons D, Donnelley M. McCarron A, et al. Among authors: donnelley m. Am J Pathol. 2020 May;190(5):977-993. doi: 10.1016/j.ajpath.2020.01.009. Epub 2020 Feb 18. Am J Pathol. 2020. PMID: 32084371 Free article.

38

Enhanced inflammasome activation and reduced sphingosine-1 phosphate S1P signalling in a respiratory mucoobstructive disease model.

Tran HB, Macowan MG, Abdo A, Donnelley M, Parsons D, Hodge S. Tran HB, et al. Among authors: donnelley m. J Inflamm (Lond). 2020 Apr 21;17:16. doi: 10.1186/s12950-020-00248-2. eCollection 2020. J Inflamm (Lond). 2020. PMID: 32336954 Free PMC article.

39

Quantification of muco-obstructive lung disease variability in mice via laboratory X-ray velocimetry.

Werdiger F, Donnelley M, Dubsky S, Murrie RP, Carnibella RP, Samarage CR, How YY, Zosky GR, Fouras A, Parsons DW, Morgan KS. Werdiger F, et al. Among authors: donnelley m. Sci Rep. 2020 Jul 2;10(1):10859. doi: 10.1038/s41598-020-67633-y. Sci Rep. 2020. PMID: 32616726 Free PMC article.

40

Will Airway Gene Therapy for Cystic Fibrosis Improve Lung Function? New Imaging Technologies Can Help Us Find Out.

Parsons D, Donnelley M. Parsons D, et al. Among authors: donnelley m. Hum Gene Ther. 2020 Sep;31(17-18):973-984. doi: 10.1089/hum.2020.153. Epub 2020 Sep 8. Hum Gene Ther. 2020. PMID: 32718206 Review.

41

Animal and Cell Culture Models for Cystic Fibrosis: Which Model Is Right for Your Application?

McCarron A, Parsons D, Donnelley M. McCarron A, et al. Among authors: donnelley m. Am J Pathol. 2021 Feb;191(2):228-242. doi: 10.1016/j.ajpath.2020.10.017. Epub 2020 Nov 21. Am J Pathol. 2021. PMID: 33232694 Free article. Review.

42

Towards Human Translation of Lentiviral Airway Gene Delivery for Cystic Fibrosis: A One-Month CFTR and Reporter Gene Study in Marmosets.

Farrow N, Cmielewski P, Delhove J, Rout-Pitt N, Vaughan L, Kuchel T, Christou C, Finnie J, Smith M, Knight E, Donnelley M, Parsons D. Farrow N, et al. Among authors: donnelley m. Hum Gene Ther. 2021 Aug;32(15-16):806-816. doi: 10.1089/hum.2020.267. Epub 2021 May 11. Hum Gene Ther. 2021. PMID: 33446042

43

The Effects of Conditioning and Lentiviral Vector Pseudotype on Short- and Long-Term Airway Reporter Gene Expression in Mice.

Carpentieri C, Farrow N, Cmielewski P, Rout-Pitt N, McCarron A, Knight E, Parsons D, Donnelley M. Carpentieri C, et al. Among authors: donnelley m. Hum Gene Ther. 2021 Aug;32(15-16):817-827. doi: 10.1089/hum.2021.031. Epub 2021 Jun 24. Hum Gene Ther. 2021. PMID: 33947249

44

Breaching the Delivery Barrier: Chemical and Physical Airway Epithelium Disruption Strategies for Enhancing Lentiviral-Mediated Gene Therapy.

McCarron A, Farrow N, Cmielewski P, Knight E, Donnelley M, Parsons D. McCarron A, et al. Among authors: donnelley m. Front Pharmacol. 2021 Apr 26;12:669635. doi: 10.3389/fphar.2021.669635. eCollection 2021. Front Pharmacol. 2021. PMID: 33981244 Free PMC article.

45

Single-Dose Lentiviral Mediated Gene Therapy Recovers CFTR Function in Cystic Fibrosis Knockout Rats.

Reyne N, Cmielewski P, McCarron A, Delhove J, Parsons D, Donnelley M. Reyne N, et al. Among authors: donnelley m. Front Pharmacol. 2021 May 18;12:682299. doi: 10.3389/fphar.2021.682299. eCollection 2021. Front Pharmacol. 2021. PMID: 34084147 Free PMC article.

46

Assessment of Lentiviral Vector Mediated CFTR Correction in Mice Using an Improved Rapid in vivo Nasal Potential Difference Measurement Protocol.

Cmielewski P, Delhove J, Donnelley M, Parsons D. Cmielewski P, et al. Among authors: donnelley m. Front Pharmacol. 2021 Jul 27;12:714452. doi: 10.3389/fphar.2021.714452. eCollection 2021. Front Pharmacol. 2021. PMID: 34385926 Free PMC article.

47

In vitro optimization of miniature bronchoscope lentiviral vector delivery for the small animal lung.

Rout-Pitt N, Donnelley M, Parsons D. Rout-Pitt N, et al. Among authors: donnelley m. Exp Lung Res. 2021 Nov;47(9):417-425. doi: 10.1080/01902148.2021.1989523. Epub 2021 Oct 11. Exp Lung Res. 2021. PMID: 34632894 Free article.

48

Effective viral-mediated lung gene therapy: is airway surface preparation necessary?

McCarron A, Cmielewski P, Drysdale V, Parsons D, Donnelley M. McCarron A, et al. Among authors: donnelley m. Gene Ther. 2023 Jun;30(6):469-477. doi: 10.1038/s41434-022-00332-7. Epub 2022 Mar 29. Gene Ther. 2023. PMID: 35351979 Free PMC article. Review.

49

Improved in-vivo airway gene transfer via magnetic-guidance, with protocol development informed by synchrotron imaging.

Donnelley M, Cmielewski P, Morgan K, Delhove J, Reyne N, McCarron A, Rout-Pitt N, Drysdale V, Carpentieri C, Spiers K, Takeuchi A, Uesugi K, Yagi N, Parsons D. Donnelley M, et al. Sci Rep. 2022 May 30;12(1):9000. doi: 10.1038/s41598-022-12895-x. Sci Rep. 2022. PMID: 35637239 Free PMC article.

50

Comparison of Physical Perturbation Devices for Enhancing Lentiviral Vector-Mediated Gene Transfer to the Airway Epithelium.

Drysdale V, Cmielewski P, Donnelley M, Reyne N, Parsons D, McCarron A. Drysdale V, et al. Among authors: donnelley m. Hum Gene Ther. 2022 Oct;33(19-20):1062-1072. doi: 10.1089/hum.2022.086. Epub 2022 Sep 15. Hum Gene Ther. 2022. PMID: 35920214

51

Essential Fatty Acid Deficiency in Cystic Fibrosis Disease Progression: Role of Genotype and Sex.

Shrestha N, McCarron A, Rout-Pitt N, Donnelley M, Parsons DW, Hryciw DH. Shrestha N, et al. Among authors: donnelley m. Nutrients. 2022 Nov 4;14(21):4666. doi: 10.3390/nu14214666. Nutrients. 2022. PMID: 36364928 Free PMC article. Review.

52

Perceptions of airway gene therapy for cystic fibrosis.

Donnelley M, Parsons D, Prichard I. Donnelley M, et al. Expert Opin Biol Ther. 2023 Jan;23(1):103-113. doi: 10.1080/14712598.2022.2150544. Epub 2022 Dec 6. Expert Opin Biol Ther. 2023. PMID: 36408943

53

To bead or not to bead: A review of Pseudomonas aeruginosa lung infection models for cystic fibrosis.

Reyne N, McCarron A, Cmielewski P, Parsons D, Donnelley M. Reyne N, et al. Among authors: donnelley m. Front Physiol. 2023 Feb 7;14:1104856. doi: 10.3389/fphys.2023.1104856. eCollection 2023. Front Physiol. 2023. PMID: 36824474 Free PMC article. Review.

54

Changes in Essential Fatty Acids and Ileal Genes Associated with Metabolizing Enzymes and Fatty Acid Transporters in Rodent Models of Cystic Fibrosis.

Shrestha N, Rout-Pitt N, McCarron A, Jackson CA, Bulmer AC, McAinch AJ, Donnelley M, Parsons DW, Hryciw DH. Shrestha N, et al. Among authors: donnelley m. Int J Mol Sci. 2023 Apr 13;24(8):7194. doi: 10.3390/ijms24087194. Int J Mol Sci. 2023. PMID: 37108362 Free PMC article.

55

Repeat or single-dose lentiviral vector administration to mouse lungs? It's all about the timing.

Donnelley M, Cmielewski P, Knight E, Carpentieri C, McCarron A, Rout-Pitt N, Parsons D, Farrow N. Donnelley M, et al. Gene Ther. 2023 Sep;30(9):698-705. doi: 10.1038/s41434-023-00403-3. Epub 2023 May 10. Gene Ther. 2023. PMID: 37165031 Free PMC article.

56

Noncontact Respiratory Motion Detection in Anesthetized Rodents.

Donnelley M, Lagerquist L, Cmielewski P, Reyne N, Morgan K, Parsons D. Donnelley M, et al. J Am Assoc Lab Anim Sci. 2023 Nov 11;62(6):559-568. doi: 10.30802/AALAS-JAALAS-23-000018. Epub 2023 Oct 10. J Am Assoc Lab Anim Sci. 2023. PMID: 37816589 Free PMC article.

57

Fetal drug exposure after maternally administered CFTR modulators Elexacaftor/Tezacaftor/Ivacaftor in a rat model.

Li D, Zhu Y, Donnelley M, Parsons D, Habgood MD, Schneider-Futschik EK. Li D, et al. Among authors: donnelley m. Biomed Pharmacother. 2024 Feb;171:116155. doi: 10.1016/j.biopha.2024.116155. Epub 2024 Jan 16. Biomed Pharmacother. 2024. PMID: 38232663 Free article.

58

Pilot study of paediatric regional lung function assessment via X-ray velocimetry (XV) imaging in children with normal lungs and in children with cystic fibrosis.

Bruorton M, Donnelley M, Goddard T, O'Connor A, Parsons D, Phillips J, Carson-Chahhoud K, Tai A. Bruorton M, et al. Among authors: donnelley m. BMJ Open. 2024 Feb 5;14(2):e080034. doi: 10.1136/bmjopen-2023-080034. BMJ Open. 2024. PMID: 38316593 Free PMC article.

59

Effect of elexacaftor-tezacaftor-ivacaftor on nasal potential difference and lung function in Phe508del rats.

Reyne N, Cmielewski P, McCarron A, Smith R, Schneider-Futschik E, Eikelis N, Pirakalathanan P, Parsons D, Donnelley M. Reyne N, et al. Among authors: donnelley m. Front Pharmacol. 2024 Mar 13;15:1362325. doi: 10.3389/fphar.2024.1362325. eCollection 2024. Front Pharmacol. 2024. PMID: 38545546 Free PMC article.

60

Ultra-fastin vivodirectional dark-field x-ray imaging for visualising magnetic control of particles for airway gene delivery.

Smith R, Morgan K, McCarron A, Cmielewski P, Reyne N, Parsons D, Donnelley M. Smith R, et al. Among authors: donnelley m. Phys Med Biol. 2024 May 9;69(10). doi: 10.1088/1361-6560/ad40f5. Phys Med Biol. 2024. PMID: 38640914

61

Extent of foetal exposure to maternal elexacaftor/tezacaftor/ivacaftor during pregnancy.

Li D, Donnelley M, Parsons D, Habgood MD, Schneider-Futschik EK. Li D, et al. Among authors: donnelley m. Br J Pharmacol. 2024 Aug;181(15):2413-2428. doi: 10.1111/bph.16417. Epub 2024 May 21. Br J Pharmacol. 2024. PMID: 38770951 Free article.

62

Corrigendum: Effect of elexacaftor-tezacaftor-ivacaftor on nasal potential difference and lung function in Phe508del rats.

Reyne N, Cmielewski P, McCarron A, Smith R, Schneider-Futschik E, Eikelis N, Pirakalathanan P, Parsons D, Donnelley M. Reyne N, et al. Among authors: donnelley m. Front Pharmacol. 2024 May 28;15:1428213. doi: 10.3389/fphar.2024.1428213. eCollection 2024. Front Pharmacol. 2024. PMID: 38863980 Free PMC article.

63

Lentiviral vector gene therapy and CFTR modulators show comparable effectiveness in cystic fibrosis rat airway models.

McCarron A, Ling KM, Montgomery ST, Martinovich KM, Cmielewski P, Rout-Pitt N, Kicic A, Parsons D, Donnelley M. McCarron A, et al. Among authors: donnelley m. Gene Ther. 2024 Nov;31(11-12):553-559. doi: 10.1038/s41434-024-00480-y. Epub 2024 Aug 25. Gene Ther. 2024. PMID: 39183346 Free PMC article.

64

Insights into epithelial-mesenchymal transition from cystic fibrosis rat models.

Rout-Pitt N, Boog B, McCarron A, Reyne N, Parsons D, Donnelley M. Rout-Pitt N, et al. Among authors: donnelley m. J Cyst Fibros. 2025 Jan;24(1):149-156. doi: 10.1016/j.jcf.2024.09.003. Epub 2024 Sep 12. J Cyst Fibros. 2025. PMID: 39266334 Free article.

65

Assessment of respiratory mechanics and X-ray velocimetry functional imaging in two cystic fibrosis rat models.

Reyne N, Smith R, Cmielewski P, Eikelis N, Lawrence M, Louise J, Pirakalathanan P, Parsons D, Donnelley M. Reyne N, et al. Among authors: donnelley m. Sci Rep. 2024 Sep 17;14(1):21646. doi: 10.1038/s41598-024-71632-8. Sci Rep. 2024. PMID: 39284856 Free PMC article.

66

CFTR High Expresser BEST4+ cells are pH-sensing neuropod cells: new implications for intestinal physiology and Cystic Fibrosis disease.

Dos Reis DC, Jin J, Santos A, Muiler C, Zagoren E, Donnelley M, Parsons D, Cmielewski P, Reyne N, McCarron A, Smith Z, Sumigray K, Ameen NA. Dos Reis DC, et al. Among authors: donnelley m. bioRxiv [Preprint]. 2025 Jan 27:2025.01.24.634747. doi: 10.1101/2025.01.24.634747. bioRxiv. 2025. PMID: 39974899 Free PMC article. Preprint.

67

Functional Lung Imaging Identifies Peripheral Ventilation Changes in ꞵ-ENaC Mice.

Reyne N, Smith R, Cmielewski P, Eikelis N, Nilsen K, Louise J, Duerr J, Mall MA, Lawrence M, Parsons D, Donnelley M. Reyne N, et al. Among authors: donnelley m. Respirology. 2025 Apr;30(4):335-345. doi: 10.1111/resp.70009. Epub 2025 Feb 25. Respirology. 2025. PMID: 39998270 Free PMC article.

68

An immunocompetent rat model of Mycobacterium abscessus multinodular granulomatous lung infection.

Feizi S, Cooksley CM, Reyne N, Boog B, Finnie J, Shaghayegh G, Hon K, Ramezanpour M, Psaltis AJ, Wormald PJ, Cmielewski P, McCarron A, Donnelley M, Parsons D, Vreugde S. Feizi S, et al. Among authors: donnelley m. Tuberculosis (Edinb). 2025 May;152:102629. doi: 10.1016/j.tube.2025.102629. Epub 2025 Mar 4. Tuberculosis (Edinb). 2025. PMID: 40056658 Free article.

69

Pediatric functional lung imaging and pulmonary function testing: a scoping review protocol.

Bruorton M, Greenslade S, Perveen S, Donnelley M, O'Connor A, Phillips J, Parsons D, Goddard T, Carson-Chahhoud K, Tai A. Bruorton M, et al. Among authors: donnelley m. JBI Evid Synth. 2025 Jul 1;23(7):1472-1478. doi: 10.11124/JBIES-24-00377. Epub 2025 Mar 26. JBI Evid Synth. 2025. PMID: 40143647

70

Visualising ventilation changes following endobronchial valve placement with x-ray velocimetry functional lung imaging.

Smith R, Thomas C, Nguyen P, Badiei A, Eikelis N, Nilsen K, Pirakalathanan P, Parsons D, Donnelley M. Smith R, et al. Among authors: donnelley m. Phys Med Biol. 2025 Jun 27;70(13). doi: 10.1088/1361-6560/ade196. Phys Med Biol. 2025. PMID: 40472865

71

CFTR High Expresser BEST4⁺ cells are pH-sensing neuropod cells: new implications for intestinal physiology and cystic fibrosis disease.

Dos Reis DC, Jin J, Santos A, Dastoor P, Muiler C, Zagoren E, Donnelley M, Parsons D, Cmielewski P, Reyne N, McCarron A, Smith Z, Sumigray K, Ameen NA. Dos Reis DC, et al. Among authors: donnelley m. Am J Physiol Cell Physiol. 2025 Nov 1;329(5):C1411-C1428. doi: 10.1152/ajpcell.00082.2025. Epub 2025 Sep 26. Am J Physiol Cell Physiol. 2025. PMID: 41005986 Free article.

72

In situ propagation-based lung computed tomography for large animal models.

D'Amico L, Costello L, Nesterets Y, Donnelley M, Gureyev T, Maksimenko A, Beck C, Ahlers J, Smith R, How YY, Parsons D, Hall C, Hausermann D, Cameron M, Klein M, Kitchen M, Tromba G, Dullin C, Morgan K. D'Amico L, et al. Among authors: donnelley m. J Synchrotron Radiat. 2025 Nov 1;32(Pt 6):1511-1522. doi: 10.1107/S160057752500832X. Epub 2025 Oct 27. J Synchrotron Radiat. 2025. PMID: 41144280 Free PMC article.

73

A longitudinal evaluation of localised chronic Pseudomonas aeruginosa infection in cystic fibrosis rat models.

Reyne N, Boog B, Cmielewski P, McCarron A, Smith R, Rout-Pitt N, Eikelis N, Nilsen K, Finnie J, Louise J, Parsons D, Donnelley M. Reyne N, et al. Among authors: donnelley m. BMC Microbiol. 2026 Mar 10;26(1):368. doi: 10.1186/s12866-026-04893-0. BMC Microbiol. 2026. PMID: 41803705 Free PMC article.

74

Capturing and visualizing transient X-ray wavefront topological features by single-grid phase imaging.

Morgan KS, Petersen TC, Donnelley M, Farrow N, Parsons DW, Paganin DM. Morgan KS, et al. Among authors: donnelley m. Opt Express. 2016 Oct 17;24(21):24435-24450. doi: 10.1364/OE.24.024435. Opt Express. 2016. PMID: 27828172 Free article.

75

Multiple mucociliary transit marker tracking in synchrotron X-ray images using the global nearest neighbor method.

Hye-Won Jung, Lee I, Sang-Heon Lee, Parsons D, Donnelley M. Hye-Won Jung, et al. Among authors: donnelley m. Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul;2017:1824-1827. doi: 10.1109/EMBC.2017.8037200. Annu Int Conf IEEE Eng Med Biol Soc. 2017. PMID: 29060244

76

Treatment of Cystic Fibrosis: From Gene- to Cell-Based Therapies.

Allan KM, Farrow N, Donnelley M, Jaffe A, Waters SA. Allan KM, et al. Among authors: donnelley m. Front Pharmacol. 2021 Mar 16;12:639475. doi: 10.3389/fphar.2021.639475. eCollection 2021. Front Pharmacol. 2021. PMID: 33796025 Free PMC article. Review.

77

Using X-ray velocimetry to measure lung function and assess the efficacy of a pseudomonas aeruginosa bacteriophage therapy for cystic fibrosis.

Harker SA, Preissner M, Chang RY, Trevascus D, Liu C, Wang Y, Chow MYT, Cmielewski P, Reyne N, How YY, Pollock JA, Klein M, Wright CA, Dubsky S, Donnelley M, Chan HK, Morgan KS. Harker SA, et al. Among authors: donnelley m. Sci Rep. 2024 Nov 29;14(1):29727. doi: 10.1038/s41598-024-80326-0. Sci Rep. 2024. PMID: 39614107 Free PMC article.

78

Gene-Corrected Basal Cells Restore CFTR In Vitro; Transplants Regenerate Epithelium in a Preclinical Sinus Model.

Allan KM, Zhang S, Wong SL, Capraro A, McCarron A, Skinner D, Kardia E, Zheng Y, Zhong L, Ng CA, Bell JL, Farrow N, Umashankar B, Banks C, Herbert C, Kilian KA, Pandzic E, Vittorio O, Vandenberg JI, Lock JG, Jaffe A, Donnelley M, Parsons D, Woodworth BA, Cho DY, Waters SA. Allan KM, et al. Among authors: donnelley m. bioRxiv [Preprint]. 2025 Jul 21:2025.07.21.666023. doi: 10.1101/2025.07.21.666023. bioRxiv. 2025. PMID: 40777307 Free PMC article. Preprint.

79

Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine.

Ousingsawat J, Centeio R, Reyne N, McCarron A, Cmielewski P, Schreiber R, diStefano G, Römermann D, Seidler U, Donnelley M, Kunzelmann K. Ousingsawat J, et al. Among authors: donnelley m. Sci Rep. 2024 Jan 17;14(1):1464. doi: 10.1038/s41598-024-51397-w. Sci Rep. 2024. PMID: 38233410 Free PMC article.

80

Real-world outcomes after initiation of Elexacaftor/tezacaftor/ivacaftor in an adolescent cohort with cystic fibrosis.

Johnston JR, Donnelley M, Smith R, Louise J, Grunert J, La Vanda C, Tai A. Johnston JR, et al. Among authors: donnelley m. Respir Med. 2025 Nov-Dec;249:108410. doi: 10.1016/j.rmed.2025.108410. Epub 2025 Oct 10. Respir Med. 2025. PMID: 41077233

81

It takes a community to conceive: an analysis of the scope, nature and accuracy of online sources of health information for couples trying to conceive.

Kedzior SGE, Bianco-Miotto T, Breen J, Diener KR, Donnelley M, Dunning KR, Penno MAS, Schjenken JE, Sharkey DJ, Hodyl NA, Fullston T, Gardiner M, Brown HM, Rumbold AR. Kedzior SGE, et al. Among authors: donnelley m. Reprod Biomed Soc Online. 2019 Oct 5;9:48-63. doi: 10.1016/j.rbms.2019.08.004. eCollection 2019 Dec. Reprod Biomed Soc Online. 2019. PMID: 32021914 Free PMC article.

82

In vivo Dynamic Phase-Contrast X-ray Imaging using a Compact Light Source.

Gradl R, Dierolf M, Günther B, Hehn L, Möller W, Kutschke D, Yang L, Donnelley M, Murrie R, Erl A, Stoeger T, Gleich B, Achterhold K, Schmid O, Pfeiffer F, Morgan KS. Gradl R, et al. Among authors: donnelley m. Sci Rep. 2018 May 1;8(1):6788. doi: 10.1038/s41598-018-24763-8. Sci Rep. 2018. PMID: 29717143 Free PMC article.

83

Visualizing treatment delivery and deposition in mouse lungs using in vivo x-ray imaging.

Gradl R, Dierolf M, Yang L, Hehn L, Günther B, Möller W, Kutschke D, Stoeger T, Gleich B, Achterhold K, Donnelley M, Pfeiffer F, Schmid O, Morgan KS. Gradl R, et al. Among authors: donnelley m. J Control Release. 2019 Aug 10;307:282-291. doi: 10.1016/j.jconrel.2019.06.035. Epub 2019 Jun 27. J Control Release. 2019. PMID: 31254554

84

Multimodal Precision Imaging of Pulmonary Nanoparticle Delivery in Mice: Dynamics of Application, Spatial Distribution, and Dosimetry.

Yang L, Gradl R, Dierolf M, Möller W, Kutschke D, Feuchtinger A, Hehn L, Donnelley M, Günther B, Achterhold K, Walch A, Stoeger T, Razansky D, Pfeiffer F, Morgan KS, Schmid O. Yang L, et al. Among authors: donnelley m. Small. 2019 Dec;15(49):e1904112. doi: 10.1002/smll.201904112. Epub 2019 Oct 22. Small. 2019. PMID: 31639283 Free article.

85

Public Acceptability of Gene Therapy and Gene Editing for Human Use: A Systematic Review.

Delhove J, Osenk I, Prichard I, Donnelley M. Delhove J, et al. Among authors: donnelley m. Hum Gene Ther. 2020 Jan;31(1-2):20-46. doi: 10.1089/hum.2019.197. Hum Gene Ther. 2020. PMID: 31802714

86

Laser fluorescence bronchoscopy for detection of fluorescent reporter genes in airway epithelia.

Rooney CP, Suter M, McLennan G, Donnelley M, Reinhardt J, Delsing A, Hoffman EA, Zabner J. Rooney CP, et al. Among authors: donnelley m. Gene Ther. 2002 Dec;9(23):1639-44. doi: 10.1038/sj.gt.3301825. Gene Ther. 2002. PMID: 12424617

87

Mapping lung cancer ventilation dynamics using functional imaging and lung mechanics.

Smith R, Reyne N, Batey D, Eikelis N, Asselin-Labat ML, Donnelley M. Smith R, et al. Among authors: donnelley m. Dis Model Mech. 2025 Dec 1;18(12):dmm052559. doi: 10.1242/dmm.052559. Epub 2025 Dec 29. Dis Model Mech. 2025. PMID: 41146618 Free PMC article.

88

Correction: High-energy X-ray phase-contrast CT of an adult human chest phantom.

Ahlers JN, D'Amico L, Bast H, Costello LF, Donnelley M, Alloo SJ, Harker SA, How YY, Croughan MK, Pollock JA, Häusermann D, Maksimenko A, Hall C, Gureyev TE, Nesterets YI, Kitchen MJ, Pavlov KM, Morgan KS. Ahlers JN, et al. Among authors: donnelley m. Sci Rep. 2025 Oct 28;15(1):37538. doi: 10.1038/s41598-025-24931-7. Sci Rep. 2025. PMID: 41152372 Free PMC article. No abstract available.

89

High-energy X-ray phase-contrast CT of an adult human chest phantom.

Ahlers JN, D Amico L, Bast H, Costello LF, Donnelley M, Alloo SJ, Harker SA, How YY, Croughan MK, Pollock JA, Häusermann D, Maksimenko A, Hall C, Gureyev TE, Nesterets YI, Kitchen MJ, Pavlov KM, Morgan KS. Ahlers JN, et al. Among authors: donnelley m. Sci Rep. 2025 Aug 11;15(1):29314. doi: 10.1038/s41598-025-14956-3. Sci Rep. 2025. PMID: 40790090 Free PMC article.

90

Evaluating the feasibility of region-of-interest X-ray phase contrast imaging for lung cancer diagnostics.

Costello L, Donnelley M, Nesterets Y, Ahlers J, Alloo S, Hall C, Hausermann D, Kitchen M, D'Amico L, Morgan K. Costello L, et al. Among authors: donnelley m. Sci Rep. 2025 Jun 6;15(1):19881. doi: 10.1038/s41598-025-04509-z. Sci Rep. 2025. PMID: 40481115 Free PMC article.

91

Increasing heterogeneity is associated with IL-6 expression in the lungs following mechanical ventilation.

Smalley E, Trevascus D, Song Y, Preissner M, Dargaville PA, Donnelley M, Morgan K, Dubsky S, Zosky GR. Smalley E, et al. Among authors: donnelley m. Am J Physiol Lung Cell Mol Physiol. 2025 May 1;328(5):L738-L747. doi: 10.1152/ajplung.00271.2024. Epub 2025 Apr 16. Am J Physiol Lung Cell Mol Physiol. 2025. PMID: 40241231 Free article.

92

Risk factors for the development of Clostridioides difficile infection in patients colonized with toxigenic Clostridioides difficile.

Clement J, Barlingay G, Addepalli S, Bang H, Donnelley MA, Cohen SH, Crabtree S. Clement J, et al. Infect Control Hosp Epidemiol. 2025 Jun;46(6):597-603. doi: 10.1017/ice.2025.4. Epub 2025 Feb 24. Infect Control Hosp Epidemiol. 2025. PMID: 39989316 Free PMC article.

93

Prevalence of antifungal allergies in the general population.

Shiferaw MW, Donnelley MA, Thompson GR 3rd. Shiferaw MW, et al. J Antimicrob Chemother. 2025 Apr 2;80(4):1080-1083. doi: 10.1093/jac/dkaf037. J Antimicrob Chemother. 2025. PMID: 39960075 Free article.

94

Vancomycin Area Under the Curve to Minimum Inhibitory Concentration Ratio for Treatment Effectiveness in Pediatric and Neonatal Staphylococcal Infections: A Systematic Review.

Chenhsu RY, Hall BA, Tran H, Donnelley MA, Cheema R, Nakra NA. Chenhsu RY, et al. J Pediatr Pharmacol Ther. 2025 Feb;30(1):52-64. doi: 10.5863/1551-6776-30.1.52. Epub 2025 Feb 10. J Pediatr Pharmacol Ther. 2025. PMID: 39935555 Free PMC article.

95

Liposomal amphotericin B and complement activation-related pseudoallergy (CARPA).

Thompson GR 3rd, Sani GM, Donnelley MA, Figueroa JK, Ciuffetelli R, Trigg K, Arredondo J, Koff A, Nearing M, Loque IC, Bays DJ, Dandekar S. Thompson GR 3rd, et al. Among authors: donnelley ma. Antimicrob Agents Chemother. 2025 Mar 5;69(3):e0169224. doi: 10.1128/aac.01692-24. Epub 2025 Jan 30. Antimicrob Agents Chemother. 2025. PMID: 39882912 Free PMC article.

96

SUBA-itraconazole in the treatment of systemic fungal infections.

Liu J, Vanderwyk KA, Donnelley MA, Thompson Iii GR. Liu J, et al. Future Microbiol. 2024 Sep;19(13):1171-1175. doi: 10.1080/17460913.2024.2362128. Epub 2024 Jul 16. Future Microbiol. 2024. PMID: 39011995 Free PMC article. Review.

97

Utility of microbial cell free DNA next-generation sequencing for diagnosis and management of infectious diseases.

Thompson RA, Donnelley MA, Trigg K, Fan S, Wilson MD, Cohen SH, Thompson GR 3rd, Desai AN. Thompson RA, et al. Diagn Microbiol Infect Dis. 2024 Sep;110(1):116334. doi: 10.1016/j.diagmicrobio.2024.116334. Epub 2024 Apr 26. Diagn Microbiol Infect Dis. 2024. PMID: 38843606 Free article.

98

Blood culture identification (BCID) performance in polymicrobial bacteremia.

Bradford WS, Donnelley MA, Fine JR, Crabtree SJ. Bradford WS, et al. Diagn Microbiol Infect Dis. 2023 Dec;107(4):116086. doi: 10.1016/j.diagmicrobio.2023.116086. Epub 2023 Sep 13. Diagn Microbiol Infect Dis. 2023. PMID: 37797380 Free PMC article.

99

Isavuconazole in the Treatment of Chronic Forms of Coccidioidomycosis.

Heidari A, Sharma R, Shakir Q, Shah M, Clement J, Donnelley MA, Reynolds T, Trigg K, Jolliff J, Kuran R, Johnson R, Thompson GR. Heidari A, et al. Among authors: donnelley ma. Clin Infect Dis. 2023 Jun 16;76(12):2196-2199. doi: 10.1093/cid/ciad146. Clin Infect Dis. 2023. PMID: 36905151 Free PMC article.

100

Impact of Vaccination on Cost and Course of Hospitalization Associated with COVID-19 Infection.

Somani ST, Firestone RL, Donnelley MA, Sanchez L, Hatfield C, Fine J, Wilson MD, Duby JJ. Somani ST, et al. Antimicrob Steward Healthc Epidemiol. 2023 Jan 25;3(1):e19. doi: 10.1017/ash.2022.364. eCollection 2023. Antimicrob Steward Healthc Epidemiol. 2023. PMID: 36714292 Free PMC article.

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