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Page 1
Novel Treatment with Intraperitoneal MOC31PE Immunotoxin in Colorectal Peritoneal Metastasis: Results From the ImmunoPeCa Phase 1 Trial.
Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Olsen KH, Giercksky KE, Julsrud L, Fodstad Ø, Dueland S, Flatmark K. Frøysnes IS, et al. Among authors: flatmark k. Ann Surg Oncol. 2017 Jul;24(7):1916-1922. doi: 10.1245/s10434-017-5814-6. Epub 2017 Feb 21. Ann Surg Oncol. 2017. PMID: 28224367 Clinical Trial.
Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft.
Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM. Fusser M, et al. Among authors: flatmark k. J Control Release. 2019 Jan 10;293:183-192. doi: 10.1016/j.jconrel.2018.11.029. Epub 2018 Dec 4. J Control Release. 2019. PMID: 30529259 Free article.
Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response.
Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K. Lund-Andersen C, et al. Among authors: flatmark k. Cold Spring Harb Mol Case Stud. 2019 Apr 1;5(2):a003566. doi: 10.1101/mcs.a003566. Print 2019 Apr. Cold Spring Harb Mol Case Stud. 2019. PMID: 30862609 Free PMC article.
The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer.
Meltzer S, Torgunrud A, Abrahamsson H, Solbakken AM, Flatmark K, Dueland S, Bakke KM, Bousquet PA, Negård A, Johansen C, Lyckander LG, Larsen FO, Schou JV, Redalen KR, Ree AH. Meltzer S, et al. Among authors: flatmark k. Br J Cancer. 2021 Jul;125(2):240-246. doi: 10.1038/s41416-021-01377-y. Epub 2021 Apr 9. Br J Cancer. 2021. PMID: 33837301 Free PMC article.
Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients.
Larsen SG, Goscinski MA, Dueland S, Steigen SE, Hofsli E, Torgunrud A, Lund-Iversen M, Dagenborg VJ, Flatmark K, Sorbye H. Larsen SG, et al. Among authors: flatmark k. Br J Cancer. 2022 Mar;126(5):726-735. doi: 10.1038/s41416-021-01620-6. Epub 2021 Dec 9. Br J Cancer. 2022. PMID: 34887523 Free PMC article.
Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192].
Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM. Fusser M, et al. Among authors: flatmark k. J Control Release. 2022 Sep;349:1. doi: 10.1016/j.jconrel.2022.06.040. Epub 2022 Jul 2. J Control Release. 2022. PMID: 35792388 Free article. No abstract available.
External multicentre validation of pseudomyxoma peritonei PSOGI-Ki67 classification.
Arjona-Sanchez A, Martinez-López A, Moreno-Montilla MT, Mulsow J, Lozano-Lominchar P, Martínez-Torres B, Rau B, Canbay E, Sommariva A, Milione M, Deraco M, Sgarbura O, Torgunrud A, Kepenekian V, Carr NJ, Hoorens A, Delhorme JB, Wernert R, Goere D, Martin-Roman L, Cosyns S, Flatmark K, Davidson B, Khellaf L, Pereira-Perez F, Rodriguez-Ortiz L, Ibáñez-Costa A, Romero-Ruiz A; EuroPMP COST action and GECOP group. Arjona-Sanchez A, et al. Among authors: flatmark k. Eur J Surg Oncol. 2023 Aug;49(8):1481-1488. doi: 10.1016/j.ejso.2023.03.206. Epub 2023 Mar 15. Eur J Surg Oncol. 2023. PMID: 36935222
Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition.
Jonsson M, Ragnum HB, Julin CH, Yeramian A, Clancy T, Frikstad KM, Seierstad T, Stokke T, Matias-Guiu X, Ree AH, Flatmark K, Lyng H. Jonsson M, et al. Among authors: flatmark k. Br J Cancer. 2016 Oct 11;115(8):929-939. doi: 10.1038/bjc.2016.278. Epub 2016 Sep 6. Br J Cancer. 2016. PMID: 27599042 Free PMC article.
Neoadjuvant chemotherapy is associated with a transient increase of intratumoral T-cell density in microsatellite stable colorectal liver metastases.
Dagenborg VJ, Marshall SE, Yaqub S, Grzyb K, Boye K, Lund-Iversen M, Høye E, Berstad AE, Fretland ÅA, Edwin B, Ree AH, Flatmark K. Dagenborg VJ, et al. Among authors: flatmark k. Cancer Biol Ther. 2020 May 3;21(5):432-440. doi: 10.1080/15384047.2020.1721252. Epub 2020 Feb 26. Cancer Biol Ther. 2020. PMID: 32098573 Free PMC article. Clinical Trial.
A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases.
Nygaard V, Ree AH, Dagenborg VJ, Børresen-Dale AL, Edwin B, Fretland ÅA, Grzyb K, Haugen MH, Mælandsmo GM, Flatmark K. Nygaard V, et al. Among authors: flatmark k. Cancer Res Commun. 2023 Feb 9;3(2):235-244. doi: 10.1158/2767-9764.CRC-22-0295. eCollection 2023 Feb. Cancer Res Commun. 2023. PMID: 36968142 Free PMC article.
Disseminated tumour cells as a prognostic biomarker in colorectal cancer.
Flatmark K, Borgen E, Nesland JM, Rasmussen H, Johannessen HO, Bukholm I, Rosales R, Hårklau L, Jacobsen HJ, Sandstad B, Boye K, Fodstad Ø. Flatmark K, et al. Br J Cancer. 2011 Apr 26;104(9):1434-9. doi: 10.1038/bjc.2011.97. Epub 2011 Mar 29. Br J Cancer. 2011. PMID: 21448171 Free PMC article.
Clinical significance of disseminated tumour cells in non-small cell lung cancer.
Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K. Rud AK, et al. Among authors: flatmark k. Br J Cancer. 2013 Sep 3;109(5):1264-70. doi: 10.1038/bjc.2013.450. Epub 2013 Aug 13. Br J Cancer. 2013. PMID: 23942067 Free PMC article.
Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer.
Kalanxhi E, Meltzer S, Schou JV, Larsen FO, Dueland S, Flatmark K, Jensen BV, Hole KH, Seierstad T, Redalen KR, Nielsen DL, Ree AH. Kalanxhi E, et al. Among authors: flatmark k. Br J Cancer. 2018 May;118(10):1322-1328. doi: 10.1038/s41416-018-0085-y. Epub 2018 Apr 26. Br J Cancer. 2018. PMID: 29695770 Free PMC article.
Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer.
Meltzer S, Negård A, Bakke KM, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Flatmark K, Ree AH. Meltzer S, et al. Among authors: flatmark k. Br J Cancer. 2022 Dec;127(12):2227-2233. doi: 10.1038/s41416-022-02004-0. Epub 2022 Oct 13. Br J Cancer. 2022. PMID: 36229579 Free PMC article. Clinical Trial.
First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer-the randomised METIMMOX trial.
Ree AH, Šaltytė Benth J, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Johansen C, Negård A, Bjørnetrø T, Nilsen HL, Berg JP, Flatmark K, Meltzer S. Ree AH, et al. Among authors: flatmark k. Br J Cancer. 2024 Jun;130(12):1921-1928. doi: 10.1038/s41416-024-02696-6. Epub 2024 Apr 25. Br J Cancer. 2024. PMID: 38664577 Free PMC article. Clinical Trial.
Nuclear S100A4 is a novel prognostic marker in colorectal cancer.
Boye K, Nesland JM, Sandstad B, Mælandsmo GM, Flatmark K. Boye K, et al. Among authors: flatmark k. Eur J Cancer. 2010 Nov;46(16):2919-25. doi: 10.1016/j.ejca.2010.07.013. Epub 2010 Aug 16. Eur J Cancer. 2010. PMID: 20719498
Expression and clinical significance of Wee1 in colorectal cancer.
Egeland EV, Flatmark K, Nesland JM, Flørenes VA, Mælandsmo GM, Boye K. Egeland EV, et al. Among authors: flatmark k. Tumour Biol. 2016 Sep;37(9):12133-12140. doi: 10.1007/s13277-016-5081-3. Epub 2016 May 24. Tumour Biol. 2016. PMID: 27220319
Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases.
Østrup O, Dagenborg VJ, Rødland EA, Skarpeteig V, Silwal-Pandit L, Grzyb K, Berstad AE, Fretland ÅA, Mælandsmo GM, Børresen-Dale AL, Ree AH, Edwin B, Nygaard V, Flatmark K. Østrup O, et al. Among authors: flatmark k. Oncotarget. 2017 Jul 18;8(44):76290-76304. doi: 10.18632/oncotarget.19350. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100312 Free PMC article.
Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study.
Ree AH, Nygaard V, Boye K, Heinrich D, Dueland S, Bergheim IR, Johansen C, Beiske K, Negård A, Lund-Iversen M, Nygaard V, Hovig E, Nakken S, Nasser S, Julsrud L, Reisse CH, Ruud EA, Kristensen VN, Flørenes VA, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Russnes HG, Mælandsmo GM, Flatmark K. Ree AH, et al. Among authors: flatmark k. Acta Oncol. 2020 Jul;59(7):733-740. doi: 10.1080/0284186X.2020.1742377. Epub 2020 Mar 25. Acta Oncol. 2020. PMID: 32208873
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium.
Pettersen EO, Ebbesen P, Gieling RG, Williams KJ, Dubois L, Lambin P, Ward C, Meehan J, Kunkler IH, Langdon SP, Ree AH, Flatmark K, Lyng H, Calzada MJ, Peso LD, Landazuri MO, Görlach A, Flamm H, Kieninger J, Urban G, Weltin A, Singleton DC, Haider S, Buffa FM, Harris AL, Scozzafava A, Supuran CT, Moser I, Jobst G, Busk M, Toustrup K, Overgaard J, Alsner J, Pouyssegur J, Chiche J, Mazure N, Marchiq I, Parks S, Ahmed A, Ashcroft M, Pastorekova S, Cao Y, Rouschop KM, Wouters BG, Koritzinsky M, Mujcic H, Cojocari D. Pettersen EO, et al. Among authors: flatmark k. J Enzyme Inhib Med Chem. 2015;30(5):689-721. doi: 10.3109/14756366.2014.966704. Epub 2014 Oct 27. J Enzyme Inhib Med Chem. 2015. PMID: 25347767 Review.
Complete response of metastatic microsatellite-stable BRAF V600E colorectal cancer to first-line oxaliplatin-based chemotherapy and immune checkpoint blockade.
Ree AH, Høye E, Esbensen Y, Beitnes AR, Negård A, Bernklev L, Tetlie LK, Fretland ÅA, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Nilsen HL, Flatmark K, Meltzer S. Ree AH, et al. Among authors: flatmark k. Oncoimmunology. 2024 Jun 28;13(1):2372886. doi: 10.1080/2162402X.2024.2372886. eCollection 2024. Oncoimmunology. 2024. PMID: 38952672 Free PMC article. Clinical Trial.
A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases.
Flørenes VA, Flem-Karlsen K, McFadden E, Bergheim IR, Nygaard V, Nygård V, Farstad IN, Øy GF, Emilsen E, Giller-Fleten K, Ree AH, Flatmark K, Gullestad HP, Hermann R, Ryder T, Wernhoff P, Mælandsmo GM. Flørenes VA, et al. Among authors: flatmark k. Transl Oncol. 2019 Jul;12(7):951-958. doi: 10.1016/j.tranon.2019.04.001. Epub 2019 May 13. Transl Oncol. 2019. PMID: 31096111 Free PMC article.
Matrix metalloproteinases participate in osteosarcoma invasion.
Bjørnland K, Flatmark K, Pettersen S, Aaasen AO, Fodstad O, Maelandsmo GM. Bjørnland K, et al. Among authors: flatmark k. J Surg Res. 2005 Aug;127(2):151-6. doi: 10.1016/j.jss.2004.12.016. Epub 2005 Apr 14. J Surg Res. 2005. PMID: 16083752
Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy.
Seierstad T, Røe K, Sitter B, Halgunset J, Flatmark K, Ree AH, Olsen DR, Gribbestad IS, Bathen TF. Seierstad T, et al. Among authors: flatmark k. Mol Cancer. 2008 Apr 25;7:33. doi: 10.1186/1476-4598-7-33. Mol Cancer. 2008. PMID: 18439252 Free PMC article.
HDAC2 deficiency and histone acetylation.
Ree AH, Folkvord S, Flatmark K. Ree AH, et al. Among authors: flatmark k. Nat Genet. 2008 Jul;40(7):812-3; author reply 813. doi: 10.1038/ng0708-812. Nat Genet. 2008. PMID: 18583969 No abstract available.
TD-11 workshop report: characterization of monoclonal antibodies to S100 proteins.
Paus E, Haugen MH, Olsen KH, Flatmark K, Maelandsmo GM, Nilsson O, Röijer E, Lundin M, Fermér C, Samsonova M, Lebedin Y, Stigbrand T. Paus E, et al. Among authors: flatmark k. Tumour Biol. 2011 Feb;32(1):1-12. doi: 10.1007/s13277-010-0073-1. Epub 2010 Jul 24. Tumour Biol. 2011. PMID: 20652782
Prediction of response to preoperative chemoradiotherapy in rectal cancer by multiplex kinase activity profiling.
Folkvord S, Flatmark K, Dueland S, de Wijn R, Grøholt KK, Hole KH, Nesland JM, Ruijtenbeek R, Boender PJ, Johansen M, Giercksky KE, Ree AH. Folkvord S, et al. Among authors: flatmark k. Int J Radiat Oncol Biol Phys. 2010 Oct 1;78(2):555-62. doi: 10.1016/j.ijrobp.2010.04.036. Epub 2010 Aug 2. Int J Radiat Oncol Biol Phys. 2010. PMID: 20675069
Nuclear legumain activity in colorectal cancer.
Haugen MH, Johansen HT, Pettersen SJ, Solberg R, Brix K, Flatmark K, Maelandsmo GM. Haugen MH, et al. Among authors: flatmark k. PLoS One. 2013;8(1):e52980. doi: 10.1371/journal.pone.0052980. Epub 2013 Jan 10. PLoS One. 2013. PMID: 23326369 Free PMC article.
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer.
Schee K, Lorenz S, Worren MM, Günther CC, Holden M, Hovig E, Fodstad O, Meza-Zepeda LA, Flatmark K. Schee K, et al. Among authors: flatmark k. PLoS One. 2013 Jun 18;8(6):e66165. doi: 10.1371/journal.pone.0066165. Print 2013. PLoS One. 2013. PMID: 23824282 Free PMC article.
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