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759 results

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Page 1
Deep conservation of the enhancer regulatory code in animals.
Wong ES, Zheng D, Tan SZ, Bower NL, Garside V, Vanwalleghem G, Gaiti F, Scott E, Hogan BM, Kikuchi K, McGlinn E, Francois M, Degnan BM. Wong ES, et al. Among authors: francois m. Science. 2020 Nov 6;370(6517):eaax8137. doi: 10.1126/science.aax8137. Science. 2020. PMID: 33154111
Sox18 genetically interacts with VegfC to regulate lymphangiogenesis in zebrafish.
Cermenati S, Moleri S, Neyt C, Bresciani E, Carra S, Grassini DR, Omini A, Goi M, Cotelli F, François M, Hogan BM, Beltrame M. Cermenati S, et al. Among authors: francois m. Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1238-47. doi: 10.1161/ATVBAHA.112.300254. Epub 2013 Mar 21. Arterioscler Thromb Vasc Biol. 2013. PMID: 23520166
Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development.
Kartopawiro J, Bower NI, Karnezis T, Kazenwadel J, Betterman KL, Lesieur E, Koltowska K, Astin J, Crosier P, Vermeren S, Achen MG, Stacker SA, Smith KA, Harvey NL, François M, Hogan BM. Kartopawiro J, et al. Among authors: francois m. Hum Mol Genet. 2014 Mar 1;23(5):1286-97. doi: 10.1093/hmg/ddt518. Epub 2013 Oct 24. Hum Mol Genet. 2014. PMID: 24163130
VEGFD regulates blood vascular development by modulating SOX18 activity.
Duong T, Koltowska K, Pichol-Thievend C, Le Guen L, Fontaine F, Smith KA, Truong V, Skoczylas R, Stacker SA, Achen MG, Koopman P, Hogan BM, Francois M. Duong T, et al. Among authors: francois m. Blood. 2014 Feb 13;123(7):1102-12. doi: 10.1182/blood-2013-04-495432. Epub 2013 Nov 22. Blood. 2014. PMID: 24269955 Free article.
Pkd1 regulates lymphatic vascular morphogenesis during development.
Coxam B, Sabine A, Bower NI, Smith KA, Pichol-Thievend C, Skoczylas R, Astin JW, Frampton E, Jaquet M, Crosier PS, Parton RG, Harvey NL, Petrova TV, Schulte-Merker S, Francois M, Hogan BM. Coxam B, et al. Among authors: francois m. Cell Rep. 2014 May 8;7(3):623-33. doi: 10.1016/j.celrep.2014.03.063. Epub 2014 Apr 24. Cell Rep. 2014. PMID: 24767999 Free PMC article.
Tmem2 Regulates Embryonic Vegf Signaling by Controlling Hyaluronic Acid Turnover.
De Angelis JE, Lagendijk AK, Chen H, Tromp A, Bower NI, Tunny KA, Brooks AJ, Bakkers J, Francois M, Yap AS, Simons C, Wicking C, Hogan BM, Smith KA. De Angelis JE, et al. Among authors: francois m. Dev Cell. 2017 Jan 23;40(2):123-136. doi: 10.1016/j.devcel.2016.12.017. Dev Cell. 2017. PMID: 28118600 Free article.
Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.
Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AA, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, Alexandrov K, Black BL, Hogan BM, De Val S, Capon RJ, Carroll JS, Bailey TL, Koopman P, Jauch R, Smyth MJ, Cooper MA, Gambin Y, Francois M. Overman J, et al. Among authors: francois m. Elife. 2017 Jan 31;6:e21221. doi: 10.7554/eLife.21221. Elife. 2017. PMID: 28137359 Free PMC article.
Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish.
Bower NI, Koltowska K, Pichol-Thievend C, Virshup I, Paterson S, Lagendijk AK, Wang W, Lindsey BW, Bent SJ, Baek S, Rondon-Galeano M, Hurley DG, Mochizuki N, Simons C, Francois M, Wells CA, Kaslin J, Hogan BM. Bower NI, et al. Among authors: francois m. Nat Neurosci. 2017 Jun;20(6):774-783. doi: 10.1038/nn.4558. Epub 2017 May 1. Nat Neurosci. 2017. PMID: 28459441
SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M. Chiang IK, et al. Among authors: francois m. Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15. Development. 2017. PMID: 28619820 Free PMC article.
A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development.
Pichol-Thievend C, Betterman KL, Liu X, Ma W, Skoczylas R, Lesieur E, Bos FL, Schulte D, Schulte-Merker S, Hogan BM, Oliver G, Harvey NL, Francois M. Pichol-Thievend C, et al. Among authors: francois m. Development. 2018 May 17;145(10):dev160184. doi: 10.1242/dev.160184. Development. 2018. PMID: 29773646 Free PMC article.
MAFB modulates the maturation of lymphatic vascular networks in mice.
Rondon-Galeano M, Skoczylas R, Bower NI, Simons C, Gordon E, Francois M, Koltowska K, Hogan BM. Rondon-Galeano M, et al. Among authors: francois m. Dev Dyn. 2020 Oct;249(10):1201-1216. doi: 10.1002/dvdy.209. Epub 2020 Jul 7. Dev Dyn. 2020. PMID: 32525258 Free article.
Pkd1 and Wnt5a genetically interact to control lymphatic vascular morphogenesis in mice.
Chau TCY, Baek S, Coxam B, Skoczylas R, Rondon-Galeano M, Bower NI, Wainwright EN, Stacker SA, Cooper HM, Koopman PA, Lagendijk AK, Harvey NL, François M, Hogan BM. Chau TCY, et al. Among authors: francois m. Dev Dyn. 2022 Feb;251(2):336-349. doi: 10.1002/dvdy.390. Epub 2021 Jul 16. Dev Dyn. 2022. PMID: 34174014 Free article.
Correction: SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development doi: 10.1242/dev.146241.
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Fossat N, Radziewic T, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Tam PPL, Carroll J, Dejana E, Schulte-Merker S, Hogan BM, Beltrame M, De Val S, Francois M. Chiang IK, et al. Among authors: francois m. Development. 2017 Oct 15;144(20):3847-3848. doi: 10.1242/dev.159715. Development. 2017. PMID: 29042478 Free PMC article. No abstract available.
Sox18 induces development of the lymphatic vasculature in mice.
François M, Caprini A, Hosking B, Orsenigo F, Wilhelm D, Browne C, Paavonen K, Karnezis T, Shayan R, Downes M, Davidson T, Tutt D, Cheah KS, Stacker SA, Muscat GE, Achen MG, Dejana E, Koopman P. François M, et al. Nature. 2008 Dec 4;456(7222):643-7. doi: 10.1038/nature07391. Epub 2008 Oct 19. Nature. 2008. PMID: 18931657
Sox factors transcriptionally regulate ROBO4 gene expression in developing vasculature in zebrafish.
Samant GV, Schupp MO, François M, Moleri S, Kothinti RK, Chun CZ, Sinha I, Sellars S, Leigh N, Pramanik K, Horswill MA, Remadevi I, Li K, Wilkinson GA, Tabatabai NM, Beltrame M, Koopman P, Ramchandran R. Samant GV, et al. Among authors: francois m. J Biol Chem. 2011 Sep 2;286(35):30740-30747. doi: 10.1074/jbc.M111.220665. Epub 2011 Jul 5. J Biol Chem. 2011. PMID: 21730073 Free PMC article.
Tmem2 Regulates Embryonic Vegf Signaling by Controlling Hyaluronic Acid Turnover.
De Angelis JE, Lagendijk AK, Chen H, Tromp A, Bower NI, Tunny KA, Brooks AJ, Bakkers J, Francois M, Yap AS, Simons C, Wicking C, Hogan BM, Smith KA. De Angelis JE, et al. Among authors: francois m. Dev Cell. 2017 Feb 27;40(4):421. doi: 10.1016/j.devcel.2017.02.005. Dev Cell. 2017. PMID: 28245926 Free article. No abstract available.
Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production.
Gramolelli S, Elbasani E, Tuohinto K, Nurminen V, Günther T, Kallinen RE, Kaijalainen SP, Diaz R, Grundhoff A, Haglund C, Ziegelbauer JM, Pellinen T, Bower M, Francois M, Ojala PM. Gramolelli S, et al. Among authors: francois m. Cancer Res. 2020 Aug 1;80(15):3116-3129. doi: 10.1158/0008-5472.CAN-19-3103. Epub 2020 Jun 9. Cancer Res. 2020. PMID: 32518203 Free PMC article.
A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.
McCann AJ, Lou J, Moustaqil M, Graus MS, Blum A, Fontaine F, Liu H, Luu W, Rudolffi-Soto P, Koopman P, Sierecki E, Gambin Y, Meunier FA, Liu Z, Hinde E, Francois M. McCann AJ, et al. Among authors: francois m. Nucleic Acids Res. 2021 Nov 8;49(19):10931-10955. doi: 10.1093/nar/gkab820. Nucleic Acids Res. 2021. PMID: 34570228 Free PMC article.
The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner.
Chiang IKN, Graus MS, Kirschnick N, Davidson T, Luu W, Harwood R, Jiang K, Li B, Wong YY, Moustaqil M, Lesieur E, Skoczylas R, Kouskoff V, Kazenwadel J, Arriola-Martinez L, Sierecki E, Gambin Y, Alitalo K, Kiefer F, Harvey NL, Francois M. Chiang IKN, et al. Among authors: francois m. EMBO J. 2023 Mar 1;42(5):e109032. doi: 10.15252/embj.2021109032. Epub 2023 Jan 30. EMBO J. 2023. PMID: 36715213 Free PMC article.
Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.
Klaus M, Prokoph N, Girbig M, Wang X, Huang YH, Srivastava Y, Hou L, Narasimhan K, Kolatkar PR, Francois M, Jauch R. Klaus M, et al. Among authors: francois m. Nucleic Acids Res. 2016 May 5;44(8):3922-35. doi: 10.1093/nar/gkw130. Epub 2016 Mar 2. Nucleic Acids Res. 2016. PMID: 26939885 Free PMC article.
Small-Molecule Inhibitors of the SOX18 Transcription Factor.
Fontaine F, Overman J, Moustaqil M, Mamidyala S, Salim A, Narasimhan K, Prokoph N, Robertson AAB, Lua L, Alexandrov K, Koopman P, Capon RJ, Sierecki E, Gambin Y, Jauch R, Cooper MA, Zuegg J, Francois M. Fontaine F, et al. Among authors: francois m. Cell Chem Biol. 2017 Mar 16;24(3):346-359. doi: 10.1016/j.chembiol.2017.01.003. Epub 2017 Feb 2. Cell Chem Biol. 2017. PMID: 28163017 Free article.
Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors.
Zhao J, Patel J, Kaur S, Sim SL, Wong HY, Styke C, Hogan I, Kahler S, Hamilton H, Wadlow R, Dight J, Hashemi G, Sormani L, Roy E, Yoder MC, Francois M, Khosrotehrani K. Zhao J, et al. Among authors: francois m. Nat Commun. 2021 May 7;12(1):2564. doi: 10.1038/s41467-021-22717-9. Nat Commun. 2021. PMID: 33963183 Free PMC article.
Possible genetic predisposition to lymphedema after breast cancer.
Newman B, Lose F, Kedda MA, Francois M, Ferguson K, Janda M, Yates P, Spurdle AB, Hayes SC. Newman B, et al. Among authors: francois m. Lymphat Res Biol. 2012 Mar;10(1):2-13. doi: 10.1089/lrb.2011.0024. Epub 2012 Mar 9. Lymphat Res Biol. 2012. PMID: 22404826 Free PMC article.
R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma.
Overman J, Fontaine F, Wylie-Sears J, Moustaqil M, Huang L, Meurer M, Chiang IK, Lesieur E, Patel J, Zuegg J, Pasquier E, Sierecki E, Gambin Y, Hamdan M, Khosrotehrani K, Andelfinger G, Bischoff J, Francois M. Overman J, et al. Among authors: francois m. Elife. 2019 Jul 30;8:e43026. doi: 10.7554/eLife.43026. Elife. 2019. PMID: 31358114 Free PMC article.
The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel.
Aspelund A, Tammela T, Antila S, Nurmi H, Leppänen VM, Zarkada G, Stanczuk L, Francois M, Mäkinen T, Saharinen P, Immonen I, Alitalo K. Aspelund A, et al. Among authors: francois m. J Clin Invest. 2014 Sep;124(9):3975-86. doi: 10.1172/JCI75395. Epub 2014 Jul 25. J Clin Invest. 2014. PMID: 25061878 Free PMC article.
Cartilage breakdown in rheumatoid arthritis.
Rannou F, François M, Corvol MT, Berenbaum F. Rannou F, et al. Among authors: francois m. Joint Bone Spine. 2006 Jan;73(1):29-36. doi: 10.1016/j.jbspin.2004.12.013. Epub 2005 Jul 6. Joint Bone Spine. 2006. PMID: 16087381 Review.
A tale of two copies: Evolutionary trajectories of moth pheromone receptors.
Li Z, Capoduro R, Bastin-Héline L, Zhang S, Sun D, Lucas P, Dabir-Moghaddam D, François MC, Liu Y, Wang G, Jacquin-Joly E, Montagné N, Meslin C. Li Z, et al. Among authors: francois mc. Proc Natl Acad Sci U S A. 2023 May 16;120(20):e2221166120. doi: 10.1073/pnas.2221166120. Epub 2023 May 8. Proc Natl Acad Sci U S A. 2023. PMID: 37155838 Free PMC article.
Vascular cells improve functionality of human cardiac organoids.
Voges HK, Foster SR, Reynolds L, Parker BL, Devilée L, Quaife-Ryan GA, Fortuna PRJ, Mathieson E, Fitzsimmons R, Lor M, Batho C, Reid J, Pocock M, Friedman CE, Mizikovsky D, Francois M, Palpant NJ, Needham EJ, Peralta M, Monte-Nieto GD, Jones LK, Smyth IM, Mehdiabadi NR, Bolk F, Janbandhu V, Yao E, Harvey RP, Chong JJH, Elliott DA, Stanley EG, Wiszniak S, Schwarz Q, James DE, Mills RJ, Porrello ER, Hudson JE. Voges HK, et al. Among authors: francois m. Cell Rep. 2023 May 30;42(5):112322. doi: 10.1016/j.celrep.2023.112322. Epub 2023 Apr 26. Cell Rep. 2023. PMID: 37105170 Free article.
Flares in IIMs and the timeline following COVID-19 vaccination: a combined analysis of the COVAD-1 and 2 surveys.
Naveen R, Sen P, Griger Z, Day J, Joshi M, Nune A, Nikiphorou E, Saha S, Tan AL, Shinjo SK, Ziade N, Velikova T, Milchert M, Jagtap K, Parodis I, Edgar Gracia-Ramos A, Cavagna L, Kuwana M, Knitza J, Chen YM, Makol A, Agarwal V, Patel A, Pauling JD, Wincup C, Barman B, Zamora Tehozol EA, Serrano JR, García-De La Torre I, Colunga-Pedraza IJ, Merayo-Chalico J, Chibuzo OC, Katchamart W, Goo PA, Shumnalieva R, Hoff LS, Kibbi EL, Halabi H, Vaidya B, Shaharir SS, Hasan ATMT, Dey D, Gutiérrez CET, Caballero-Uribe CV, Lilleker JB, Salim B, Gheita T, Chatterjee T, Distler O, Saavedra MA; COVAD study group; Chinoy H, Agarwal V, Aggarwal R, Gupta L. Naveen R, et al. Rheumatology (Oxford). 2023 Apr 21:kead180. doi: 10.1093/rheumatology/kead180. Online ahead of print. Rheumatology (Oxford). 2023. PMID: 37084267
Reducing Sitting Time in Type 1 Diabetes: Considerations and Implications.
Alobaid AM, Dempsey PC, Francois M, Zulyniak MA, Hopkins M, Campbell MD. Alobaid AM, et al. Among authors: francois m. Can J Diabetes. 2023 Apr;47(3):300-304. doi: 10.1016/j.jcjd.2023.02.003. Epub 2023 Feb 11. Can J Diabetes. 2023. PMID: 36872136 Free article. Review.
Peripartum women's perspectives on research study participation in the OneFlorida Clinical Research Consortium during COVID-19 pandemic.
Xu K, Hsiao CJ, Ballard H, Chachad N, Reeder CF, Shenkman EA, Flood-Grady E, Louis-Jacques AF, Smith EL, Thompson LA, Krieger J, Francois M, Lemas DJ. Xu K, et al. Among authors: francois m. J Clin Transl Sci. 2022 Oct 10;7(1):e24. doi: 10.1017/cts.2022.476. eCollection 2023. J Clin Transl Sci. 2022. PMID: 36755549 Free PMC article.
Evolutionary Landscape of SOX Genes to Inform Genotype-to-Phenotype Relationships.
Underwood A, Rasicci DT, Hinds D, Mitchell JT, Zieba JK, Mills J, Arnold NE, Cook TW, Moustaqil M, Gambin Y, Sierecki E, Fontaine F, Vanderweele S, Das AS, Cvammen W, Sirpilla O, Soehnlen X, Bricker K, Alokaili M, Green M, Heeringa S, Wilstermann AM, Freeland TM, Qutob D, Milsted A, Jauch R, Triche TJ Jr, Krawczyk CM, Bupp CP, Rajasekaran S, Francois M, Prokop JW. Underwood A, et al. Among authors: francois m. Genes (Basel). 2023 Jan 14;14(1):222. doi: 10.3390/genes14010222. Genes (Basel). 2023. PMID: 36672963 Free PMC article.
Need and Interest in Nature Prescriptions to Protect Cardiovascular and Mental Health: A Nationally-Representative Study With Insights for Future Randomised Trials.
Astell-Burt T, Hipp JA, Gatersleben B, Adlakha D, Marselle M, Olcoń K, Pappas E, Kondo M, Booth G, Bacon S, Lem M, Francois M, Halcomb E, Moxham L, Davidson P, Feng X. Astell-Burt T, et al. Among authors: francois m. Heart Lung Circ. 2023 Jan;32(1):114-123. doi: 10.1016/j.hlc.2022.11.008. Epub 2023 Jan 2. Heart Lung Circ. 2023. PMID: 36588036
Intact Fish Skin Graft vs. Standard of Care in Patients with Neuroischaemic Diabetic Foot Ulcers (KereFish Study): An International, Multicentre, Double-Blind, Randomised, Controlled Trial Study Design and Rationale.
Dardari D, Potier L, Sultan A, Francois M, M'Bemba J, Bouillet B, Chaillous L, Kessler L, Carlier A, Jalek A, Sbaa A, Orlando L, Bobony E, Detournay B, Kjartansson H, Bjorg Arsaelsdottir R, Baldursson BT, Charpentier G. Dardari D, et al. Among authors: m bemba j, francois m. Medicina (Kaunas). 2022 Dec 1;58(12):1775. doi: 10.3390/medicina58121775. Medicina (Kaunas). 2022. PMID: 36556977 Free PMC article. Clinical Trial.
First chromosome scale genomes of ithomiine butterflies (Nymphalidae: Ithomiini): Comparative models for mimicry genetic studies.
Gauthier J, Meier J, Legeai F, McClure M, Whibley A, Bretaudeau A, Boulain H, Parrinello H, Mugford ST, Durbin R, Zhou C, McCarthy S, Wheat CW, Piron-Prunier F, Monsempes C, François MC, Jay P, Noûs C, Persyn E, Jacquin-Joly E, Meslin C, Montagné N, Lemaitre C, Elias M. Gauthier J, et al. Among authors: francois mc. Mol Ecol Resour. 2023 May;23(4):872-885. doi: 10.1111/1755-0998.13749. Epub 2023 Jan 27. Mol Ecol Resour. 2023. PMID: 36533297 Free article.
Efficacy and Safety of Osilodrostat in Paraneoplastic Cushing Syndrome: A Real-World Multicenter Study in France.
Dormoy A, Haissaguerre M, Vitellius G, Do Cao C, Geslot A, Drui D, Lasolle H, Vieira-Pinto O, Salenave S, François M, Puerto M, Boullay HD, Mayer A, Rod A, Laurent C, Chanson P, Reznik Y, Castinetti F, Chabre O, Baudin E, Raverot G, Tabarin A, Young J. Dormoy A, et al. Among authors: francois m. J Clin Endocrinol Metab. 2023 May 17;108(6):1475-1487. doi: 10.1210/clinem/dgac691. J Clin Endocrinol Metab. 2023. PMID: 36470583 Free PMC article.
Safety and tolerance of vaccines against SARS-CoV-2 infection in systemic lupus erythematosus: results from the COVAD study.
R N, Nikiphorou E, Joshi M, Sen P, Lindblom J, Agarwal V, Lilleker JB, Tan AL, Salim B, Ziade N, Velikova T, Edgar Gracia-Ramos A, Kuwana M, Day J, Makol A, Distler O, Chinoy H, Traboco LS, Kusumo Wibowo SA, Zamora Tehozol EA, Serrano JR, La Torre IG; COVAD Study Group; Aggarwal R, Gupta L, Agarwal V, Parodis I. R N, et al. Rheumatology (Oxford). 2022 Nov 22:keac661. doi: 10.1093/rheumatology/keac661. Online ahead of print. Rheumatology (Oxford). 2022. PMID: 36413073 Free article.
759 results