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Direct Delivery of Antisense Oligonucleotides to the Middle and Inner Ear Improves Hearing and Balance in Usher Mice.
Lentz JJ, Pan B, Ponnath A, Tran CM, Nist-Lund C, Galvin A, Goldberg H, Robillard KN, Jodelka FM, Farris HE, Huang J, Chen T, Zhu H, Zhou W, Rigo F, Hastings ML, Géléoc GSG. Lentz JJ, et al. Among authors: geleoc gsg. Mol Ther. 2020 Dec 2;28(12):2662-2676. doi: 10.1016/j.ymthe.2020.08.002. Epub 2020 Aug 5. Mol Ther. 2020. PMID: 32818431 Free PMC article.
Sound strategies for hearing restoration.
Géléoc GS, Holt JR. Géléoc GS, et al. Science. 2014 May 9;344(6184):1241062. doi: 10.1126/science.1241062. Science. 2014. PMID: 24812404 Free PMC article. Review.
Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss.
György B, Nist-Lund C, Pan B, Asai Y, Karavitaki KD, Kleinstiver BP, Garcia SP, Zaborowski MP, Solanes P, Spataro S, Schneider BL, Joung JK, Géléoc GSG, Holt JR, Corey DP. György B, et al. Among authors: geleoc gsg. Nat Med. 2019 Jul;25(7):1123-1130. doi: 10.1038/s41591-019-0500-9. Epub 2019 Jul 3. Nat Med. 2019. PMID: 31270503 Free PMC article.
A hop, skip, and a jump to evade USH2A deaf-blindness mutations.
Mauriac SA, Géléoc GSG. Mauriac SA, et al. Among authors: geleoc gsg. Mol Ther. 2021 Aug 4;29(8):2391-2393. doi: 10.1016/j.ymthe.2021.07.008. Epub 2021 Jul 23. Mol Ther. 2021. PMID: 34297918 Free PMC article. No abstract available.
TMC function, dysfunction, and restoration in mouse vestibular organs.
Ratzan EM, Lee J, Madison MA, Zhu H, Zhou W, Géléoc GSG, Holt JR. Ratzan EM, et al. Among authors: geleoc gsg. Front Neurol. 2024 Apr 4;15:1356614. doi: 10.3389/fneur.2024.1356614. eCollection 2024. Front Neurol. 2024. PMID: 38638308 Free PMC article.
Split otoferlins reunited.
Holt JR, Geleoc GS. Holt JR, et al. EMBO Mol Med. 2019 Jan;11(1):e9995. doi: 10.15252/emmm.201809995. EMBO Mol Med. 2019. PMID: 30573543 Free PMC article.
Grxcr2 is required for stereocilia morphogenesis in the cochlea.
Avenarius MR, Jung JY, Askew C, Jones SM, Hunker KL, Azaiez H, Rehman AU, Schraders M, Najmabadi H, Kremer H, Smith RJH, Géléoc GSG, Dolan DF, Raphael Y, Kohrman DC. Avenarius MR, et al. Among authors: geleoc gsg. PLoS One. 2018 Aug 29;13(8):e0201713. doi: 10.1371/journal.pone.0201713. eCollection 2018. PLoS One. 2018. PMID: 30157177 Free PMC article.
Cochlear function: hearing in the fast lane.
Ashmore J, Géléoc GS. Ashmore J, et al. Curr Biol. 1999 Jul 29-Aug 12;9(15):R572-4. doi: 10.1016/s0960-9822(99)80358-3. Curr Biol. 1999. PMID: 10469559 Free article. Review.
Light at the end of the tunnel of Corti.
Hanlon K, Büning H, Géléoc GSG. Hanlon K, et al. Among authors: geleoc gsg. Mol Ther Methods Clin Dev. 2023 May 23;29:437-438. doi: 10.1016/j.omtm.2023.05.006. eCollection 2023 Jun 8. Mol Ther Methods Clin Dev. 2023. PMID: 37273898 Free PMC article. No abstract available.