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Page 1
Upper respiratory tract immunization with Pam2Cys-adjuvanted spike protein vaccine achieves sterilizing protection against SARS-CoV-2.
Stewart EL, Stockdale S, Johansen MD, Smith L, Alca S, Maxwell JWC, Nguyen DH, Miemczyk S, Zhao G, Turville S, Triccas JA, Steain M, Byrne SN, Hansbro PM, Payne RJ, Britton WJ, Ashhurst AS. Stewart EL, et al. Among authors: hansbro pm. Front Immunol. 2025 Sep 2;16:1654126. doi: 10.3389/fimmu.2025.1654126. eCollection 2025. Front Immunol. 2025. PMID: 40963609 Free PMC article.
Prevention of Adverse Cardiovascular Events Using the 23-Valent Pneumococcal Polysaccharide Vaccine: A Randomized Clinical Trial.
Hure A, Peel R, D'Este C, Abhayaratna WP, Tonkin A, Hopper I, Thrift AG, Levi C, Sturm J, Durrheim D, Hung J, Briffa T, Chew DP, Ren S, McEvoy M, Hansbro P, Newby D, Szwec S, Chiu S, Attia J. Hure A, et al. Among authors: hansbro p. JAMA Cardiol. 2025 Sep 17:e253043. doi: 10.1001/jamacardio.2025.3043. Online ahead of print. JAMA Cardiol. 2025. PMID: 40960793
Osteoprotegerin Is Elevated in Pulmonary Fibrosis and Associates with Idiopathic Pulmonary Fibrosis Progression: A Pilot Study.
Habibie H, Putri KSS, Boorsma CE, Brass DM, Heukels P, Wijsenbeek M, Kool M, van den Berge M, Borghuis T, Vaughan A, Corte T, Liu G, Brandsma CA, Gan CT, Olinga P, Timens W, Kahn N, Hansbro PM, Kreuter M, Burgess JK, Melgert BN. Habibie H, et al. Among authors: hansbro pm. Respiration. 2025 Aug 13:1-14. doi: 10.1159/000547439. Online ahead of print. Respiration. 2025. PMID: 40815109 Free PMC article.
A COVID-19 rapid antigen test employing upconversion nanoparticles.
Zhang L, Zhou J, Shimoni O, Wen S, Alghalayini A, Liu Y, Rezaeishahmirzadi M, Liao J, Maddahfar M, Hunt R, Black M, Johansen MD, Hansbro PM, Zhang L, Stenzel M, Warkiani M, Valenzuela SM, Jin D. Zhang L, et al. Among authors: hansbro pm. Smart Mol. 2025 Jan 5;3(1):e20240042. doi: 10.1002/smo.20240042. eCollection 2025 Mar. Smart Mol. 2025. PMID: 40625564 Free PMC article.
Microbial contribution to metabolic niche formation varies across the respiratory tract.
Wong KK, Wu BG, Chung M, Li Q, Darawshy F, Tsay JJ, Holub M, Barnett CR, Kwok B, Kugler MC, Chung C, Natalini JG, Singh S, Li Y, Schluger R, Ficaro L, Carpenito J, Collazo D, Perez L, Kyeremateng Y, Chang M, Czachor A, Singh R, Mccormick C, Campbell CD, Keane R, Askenazi M, Hansbro PM, Weiden MD, Huang YJ, Stringer KA, Clemente JC, Li H, Jones D, Ghedin E, Segal LN, Sulaiman I. Wong KK, et al. Among authors: hansbro pm. Cell Host Microbe. 2025 Jul 9;33(7):1073-1088.e6. doi: 10.1016/j.chom.2025.06.002. Epub 2025 Jun 26. Cell Host Microbe. 2025. PMID: 40578342
An adjuvanted chimeric spike antigen boosts lung-resident memory T-cells and induces pan-sarbecovirus protective immunity.
Counoupas C, Chan E, Pino P, Armitano J, Johansen MD, Smith LJ, Ashley CL, Estapé E, Troyon J, Alca S, Miemczyk S, Hansbro NG, Scandurra G, Britton WJ, Courant T, Dubois PM, Collin N, Mohan VK, Hansbro PM, Wurm MJ, Wurm FM, Steain M, Triccas JA. Counoupas C, et al. Among authors: hansbro pm. NPJ Vaccines. 2025 May 8;10(1):89. doi: 10.1038/s41541-025-01144-7. NPJ Vaccines. 2025. PMID: 40341541 Free PMC article.
Female sex hormones and the oral contraceptive pill modulate asthma severity through GLUT-1.
Brown AC, Carroll OR, Mayall JR, Zounemat-Kermani N, Vinzenz SLE, Gomez HM, Mills EF, Kim RY, Donovan C, Baines KJ, Williams EJ, Berthon BS, Wynne K, Scott HA, Pinkerton JW, Guo Y, Hansbro PM, Foster PS, Wark PAB, Dahlen SE, Adcock IM, Wood LG, Horvat JC. Brown AC, et al. Among authors: hansbro pm. Mucosal Immunol. 2025 Jun;18(3):656-667. doi: 10.1016/j.mucimm.2025.02.006. Epub 2025 Feb 26. Mucosal Immunol. 2025. PMID: 40021011 Free article.
Vitronectin regulates lung tissue remodeling and emphysema in chronic obstructive pulmonary disease.
Liu G, Hsu AC, Geirnaert S, Cong C, Nair PM, Shen S, Marshall JE, Haw TJ, Fricker M, Philp AM, Hansbro NG, Pavlidis S, Guo Y, Burgess JK, Castellano L, Ieni A, Caramori G, Oliver BGG, Chung KF, Adcock IM, Knight DA, Polverino F, Bracke K, Wark PA, Hansbro PM. Liu G, et al. Mol Ther. 2025 Mar 5;33(3):917-932. doi: 10.1016/j.ymthe.2025.01.032. Epub 2025 Jan 21. Mol Ther. 2025. PMID: 39838644
Cigarette smoke components modulate the MR1-MAIT axis.
Awad W, Mayall JR, Xu W, Johansen MD, Patton T, Lim XY, Galvao I, Howson LJ, Brown AC, Haw TJ, Donovan C, Das S, Albers GJ, Pai TY, Hortle E, Gillis CM, Hansbro NG, Horvat JC, Liu L, Mak JYW, McCluskey J, Fairlie DP, Corbett AJ, Hansbro PM, Rossjohn J. Awad W, et al. Among authors: hansbro pm, hansbro ng. J Exp Med. 2025 Feb 3;222(2):e20240896. doi: 10.1084/jem.20240896. Epub 2025 Jan 17. J Exp Med. 2025. PMID: 39820322 Free PMC article.
Influence of gut and lung dysbiosis on lung cancer progression and their modulation as promising therapeutic targets: a comprehensive review.
Thapa R, Magar AT, Shrestha J, Panth N, Idrees S, Sadaf T, Bashyal S, Elwakil BH, Sugandhi VV, Rojekar S, Nikhate R, Gupta G, Singh SK, Dua K, Hansbro PM, Paudel KR. Thapa R, et al. MedComm (2020). 2024 Nov 24;5(12):e70018. doi: 10.1002/mco2.70018. eCollection 2024 Dec. MedComm (2020). 2024. PMID: 39584048 Free PMC article. Review.
Therapeutic potential of 18-β-glycyrrhetinic acid-loaded poly (lactic-co-glycolic acid) nanoparticles on cigarette smoke-induced in-vitro model of COPD.
El Sherkawi T, Bani Saeid A, Yeung S, Chellappan DK, Mohamad S, Kokkinis S, Sudhakar S, Singh SK, Gupta G, Paudel KR, Hansbro PM, Oliver B, De Rubis G, Dua K. El Sherkawi T, et al. Pathol Res Pract. 2024 Nov;263:155629. doi: 10.1016/j.prp.2024.155629. Epub 2024 Sep 28. Pathol Res Pract. 2024. PMID: 39348749 Free article.
Identification of Genetic Factors Associated With DAMP Release in COPD Patients.
Boedijono FS, Bood V, Eichhorn IA, Hansbro PM, Slebos DJ, van den Berge M, Faiz A, Pouwels SD. Boedijono FS, et al. Arch Bronconeumol. 2024 Nov;60(11):714-717. doi: 10.1016/j.arbres.2024.06.020. Epub 2024 Jul 8. Arch Bronconeumol. 2024. PMID: 39034199 Free article. English, Spanish. No abstract available.
Computational and biological approaches in repurposing ribavirin for lung cancer treatment: Unveiling antitumorigenic strategies.
Paudel KR, Singh M, De Rubis G, Kumbhar P, Mehndiratta S, Kokkinis S, El-Sherkawi T, Gupta G, Singh SK, Malik MZ, Mohammed Y, Oliver BG, Disouza J, Patravale V, Hansbro PM, Dua K. Paudel KR, et al. Among authors: hansbro pm. Life Sci. 2024 Sep 1;352:122859. doi: 10.1016/j.lfs.2024.122859. Epub 2024 Jun 25. Life Sci. 2024. PMID: 38925223 Free article.
Poxviridae Pneumonia.
Nucera F, Bonina L, Cipolla A, Pirina P, Hansbro PM, Adcock IM, Caramori G. Nucera F, et al. Among authors: hansbro pm. Adv Exp Med Biol. 2024;1451:183-204. doi: 10.1007/978-3-031-57165-7_12. Adv Exp Med Biol. 2024. PMID: 38801579 Review.
Targeting respiratory microbiomes in COPD and bronchiectasis.
Mac Aogáin M, Tiew PY, Jaggi TK, Narayana JK, Singh S, Hansbro PM, Segal LN, Chotirmall SH. Mac Aogáin M, et al. Expert Rev Respir Med. 2024 Mar-Apr;18(3-4):111-125. doi: 10.1080/17476348.2024.2355155. Epub 2024 Jun 12. Expert Rev Respir Med. 2024. PMID: 38743428 Review.
Lung Tissue Multilayer Network Analysis Uncovers the Molecular Heterogeneity of Chronic Obstructive Pulmonary Disease.
Olvera N, Sánchez-Valle J, Núñez-Carpintero I, Rojas-Quintero J, Noell G, Casas-Recasens S, Faiz A, Hansbro P, Guirao A, Lepore R, Cirillo D, Agustí A, Polverino F, Valencia A, Faner R. Olvera N, et al. Among authors: hansbro p. Am J Respir Crit Care Med. 2024 Nov 15;210(10):1219-1229. doi: 10.1164/rccm.202303-0500OC. Am J Respir Crit Care Med. 2024. PMID: 38626356 Free article.
Differential expression of mast cells in the small airways and alveolar septa of current smokers and patients with small airway disease and COPD.
Eapen MS, Lu W, Dey S, Chia C, Hardikar A, Hassan MI, Bhattarai P, Gaikwad AV, Das S, Hansbro PM, Singhera GK, Hackett TL, Sohal SS. Eapen MS, et al. Among authors: hansbro pm. ERJ Open Res. 2024 Mar 18;10(2):00579-2023. doi: 10.1183/23120541.00579-2023. eCollection 2024 Mar. ERJ Open Res. 2024. PMID: 38500797 Free PMC article.
Faecal microbial transfer and complex carbohydrates mediate protection against COPD.
Budden KF, Shukla SD, Bowerman KL, Vaughan A, Gellatly SL, Wood DLA, Lachner N, Idrees S, Rehman SF, Faiz A, Patel VK, Donovan C, Alemao CA, Shen S, Amorim N, Majumder R, Vanka KS, Mason J, Haw TJ, Tillet B, Fricker M, Keely S, Hansbro N, Belz GT, Horvat J, Ashhurst T, van Vreden C, McGuire H, Fazekas de St Groth B, King NJC, Crossett B, Cordwell SJ, Bonaguro L, Schultze JL, Hamilton-Williams EE, Mann E, Forster SC, Cooper MA, Segal LN, Chotirmall SH, Collins P, Bowman R, Fong KM, Yang IA, Wark PAB, Dennis PG, Hugenholtz P, Hansbro PM. Budden KF, et al. Among authors: hansbro pm, hansbro n. Gut. 2024 Apr 5;73(5):751-769. doi: 10.1136/gutjnl-2023-330521. Gut. 2024. PMID: 38331563 Clinical Trial.
Airway "Resistotypes" and Clinical Outcomes in Bronchiectasis.
Mac Aogáin M, Ivan FX, Jaggi TK, Richardson H, Shoemark A, Narayana JK, Dicker AJ, Koh MS, Lee KCH, Thun How O, Poh ME, Chin KK, Hou ALY, Ser Hon P, Low TB, Abisheganaden JA, Dimakou K, Digalaki A, Kosti C, Gkousiou A, Hansbro PM, Blasi F, Aliberti S, Chalmers JD, Chotirmall SH. Mac Aogáin M, et al. Among authors: hansbro pm. Am J Respir Crit Care Med. 2024 Jul 1;210(1):47-62. doi: 10.1164/rccm.202306-1059OC. Am J Respir Crit Care Med. 2024. PMID: 38271608 Free PMC article.
Interferon-epsilon is a novel regulator of NK cell responses in the uterus.
Mayall JR, Horvat JC, Mangan NE, Chevalier A, McCarthy H, Hampsey D, Donovan C, Brown AC, Matthews AY, de Weerd NA, de Geus ED, Starkey MR, Kim RY, Daly K, Goggins BJ, Keely S, Maltby S, Baldwin R, Foster PS, Boyle MJ, Tanwar PS, Huntington ND, Hertzog PJ, Hansbro PM. Mayall JR, et al. EMBO Mol Med. 2024 Feb;16(2):267-293. doi: 10.1038/s44321-023-00018-6. Epub 2024 Jan 23. EMBO Mol Med. 2024. PMID: 38263527 Free PMC article.
Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction.
Hardy SA, Liesinger L, Patrick R, Poettler M, Rech L, Gindlhuber J, Mabotuwana NS, Ashour D, Stangl V, Bigland M, Murtha LA, Starkey MR, Scherr D, Hansbro PM, Hoefler G, Campos Ramos G, Cochain C, Harvey RP, Birner-Gruenberger R, Boyle AJ, Rainer PP. Hardy SA, et al. Among authors: hansbro pm. JACC Basic Transl Sci. 2023 Aug 16;8(12):1539-1554. doi: 10.1016/j.jacbts.2023.05.010. eCollection 2023 Dec. JACC Basic Transl Sci. 2023. PMID: 38205347 Free PMC article.
Characterization and inhibition of inflammasome responses in severe and non-severe asthma.
Horvat JC, Kim RY, Weaver N, Augood C, Brown AC, Donovan C, Dupre P, Gunawardhana L, Mayall JR, Hansbro NG, Robertson AAB, O'Neill LAJ, Cooper MA, Holliday EG, Hansbro PM, Gibson PG. Horvat JC, et al. Among authors: hansbro pm, hansbro ng. Respir Res. 2023 Dec 4;24(1):303. doi: 10.1186/s12931-023-02603-2. Respir Res. 2023. PMID: 38044426 Free PMC article.
Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease.
De Rubis G, Paudel KR, Corrie L, Mehndiratta S, Patel VK, Kumbhar PS, Manjappa AS, Disouza J, Patravale V, Gupta G, Manandhar B, Rajput R, Robinson AK, Reyes RJ, Chakraborty A, Chellappan DK, Singh SK, Oliver BGG, Hansbro PM, Dua K. De Rubis G, et al. Naunyn Schmiedebergs Arch Pharmacol. 2024 May;397(5):2793-2833. doi: 10.1007/s00210-023-02830-w. Epub 2023 Nov 22. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 37991539 Review.
TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase.
Liu G, Haw TJ, Starkey MR, Philp AM, Pavlidis S, Nalkurthi C, Nair PM, Gomez HM, Hanish I, Hsu AC, Hortle E, Pickles S, Rojas-Quintero J, Estepar RSJ, Marshall JE, Kim RY, Collison AM, Mattes J, Idrees S, Faiz A, Hansbro NG, Fukui R, Murakami Y, Cheng HS, Tan NS, Chotirmall SH, Horvat JC, Foster PS, Oliver BG, Polverino F, Ieni A, Monaco F, Caramori G, Sohal SS, Bracke KR, Wark PA, Adcock IM, Miyake K, Sin DD, Hansbro PM. Liu G, et al. Nat Commun. 2023 Nov 14;14(1):7349. doi: 10.1038/s41467-023-42913-z. Nat Commun. 2023. PMID: 37963864 Free PMC article.
Persistence of Detectable Anti-Pneumococcal Antibodies 4 Years After Pneumococcal Polysaccharide Vaccination in a Randomised Controlled Trial: The Australian Study for the Prevention through Immunisation of Cardiovascular Events (AUSPICE).
Attia J, Horvat JC, Hunter T, Hansbro PM, Hure A, Peel R, Ren S, Dizon J, Chiu S, Srikusalanukul W, Greenough R, Abhayaratna WP; AUSPICE Investigators. Attia J, et al. Among authors: hansbro pm. Heart Lung Circ. 2023 Nov;32(11):1378-1385. doi: 10.1016/j.hlc.2023.09.006. Epub 2023 Oct 31. Heart Lung Circ. 2023. PMID: 37919117 Free article. Clinical Trial.
Zerumbone liquid crystalline nanoparticles protect against oxidative stress, inflammation and senescence induced by cigarette smoke extract in vitro.
Paudel KR, Clarence DD, Panth N, Manandhar B, De Rubis G, Devkota HP, Gupta G, Zacconi FC, Williams KA, Pont LG, Singh SK, Warkiani ME, Adams J, MacLoughlin R, Oliver BG, Chellappan DK, Hansbro PM, Dua K. Paudel KR, et al. Naunyn Schmiedebergs Arch Pharmacol. 2024 Apr;397(4):2465-2483. doi: 10.1007/s00210-023-02760-7. Epub 2023 Oct 18. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 37851060 Free PMC article.
Pre-clinical lung squamous cell carcinoma mouse models to identify novel biomarkers and therapeutic interventions.
Sahu P, Donovan C, Paudel KR, Pickles S, Chimankar V, Kim RY, Horvart JC, Dua K, Ieni A, Nucera F, Bielefeldt-Ohmann H, Mazilli S, Caramori G, Lyons JG, Hansbro PM. Sahu P, et al. Among authors: hansbro pm. Front Oncol. 2023 Sep 25;13:1260411. doi: 10.3389/fonc.2023.1260411. eCollection 2023. Front Oncol. 2023. PMID: 37817767 Free PMC article. Review.
Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection.
Ullah TR, Johansen MD, Balka KR, Ambrose RL, Gearing LJ, Roest J, Vivian JP, Sapkota S, Jayasekara WSN, Wenholz DS, Aldilla VR, Zeng J, Miemczyk S, Nguyen DH, Hansbro NG, Venkatraman R, Kang JH, Pang ES, Thomas BJ, Alharbi AS, Rezwan R, O'Keeffe M, Donald WA, Ellyard JI, Wong W, Kumar N, Kile BT, Vinuesa CG, Kelly GE, Laczka OF, Hansbro PM, De Nardo D, Gantier MP. Ullah TR, et al. Among authors: hansbro pm, hansbro ng. Nat Commun. 2023 Sep 18;14(1):5666. doi: 10.1038/s41467-023-41381-9. Nat Commun. 2023. PMID: 37723181 Free PMC article.
IL-33 Expression Is Lower in Current Smokers at both Transcriptomic and Protein Levels.
Faiz A, Mahbub RM, Boedijono FS, Tomassen MI, Kooistra W, Timens W, Nawijn M, Hansbro PM, Johansen MD, Pouwels SD, Heijink IH, Massip F, de Biase MS, Schwarz RF, Adcock IM, Chung KF, van der Does A, Hiemstra PS, Goulaouic H, Xing H, Abdulai R, de Rinaldis E, Cunoosamy D, Harel S, Lederer D, Nivens MC, Wark PA, Kerstjens HAM, Hylkema MN, Brandsma CA, van den Berge M. Faiz A, et al. Am J Respir Crit Care Med. 2023 Nov 15;208(10):1075-1087. doi: 10.1164/rccm.202210-1881OC. Am J Respir Crit Care Med. 2023. PMID: 37708400 Free PMC article.
Lower Airway Dysbiosis Augments Lung Inflammatory Injury in Mild-to-Moderate Chronic Obstructive Pulmonary Disease.
Sulaiman I, Wu BG, Chung M, Isaacs B, Tsay JJ, Holub M, Barnett CR, Kwok B, Kugler MC, Natalini JG, Singh S, Li Y, Schluger R, Carpenito J, Collazo D, Perez L, Kyeremateng Y, Chang M, Campbell CD, Hansbro PM, Oppenheimer BW, Berger KI, Goldring RM, Koralov SB, Weiden MD, Xiao R, D'Armiento J, Clemente JC, Ghedin E, Segal LN. Sulaiman I, et al. Am J Respir Crit Care Med. 2023 Nov 15;208(10):1101-1114. doi: 10.1164/rccm.202210-1865OC. Am J Respir Crit Care Med. 2023. PMID: 37677136 Free PMC article.
Gut microbiota from patients with COVID-19 cause alterations in mice that resemble post-COVID symptoms.
Mendes de Almeida V, Engel DF, Ricci MF, Cruz CS, Lopes ÍS, Alves DA, d' Auriol M, Magalhães J, Machado EC, Rocha VM, Carvalho TG, Lacerda LSB, Pimenta JC, Aganetti M, Zuccoli GS, Smith BJ, Carregari VC, da Silva Rosa E, Galvão I, Dantas Cassali G, Garcia CC, Teixeira MM, André LC, Ribeiro FM, Martins FS, Saia RS, Costa VV, Martins-de-Souza D, Hansbro PM, Marques JT, Aguiar ERGR, Vieira AT. Mendes de Almeida V, et al. Gut Microbes. 2023 Dec;15(2):2249146. doi: 10.1080/19490976.2023.2249146. Gut Microbes. 2023. PMID: 37668317 Free PMC article.
Genetic and Epigenetic Associations with Pre-Chronic Obstructive Pulmonary Disease Lung Function Trajectories.
Martino DJ, Bui DS, Li S, Idrose S, Perret J, Lowe AJ, Lodge CJ, Bowatte G, Moodley Y, Thomas PS, Zosky G, Hansbro PM, Holloway JW, Svanes C, Faner R, Walters EH, Dharmage SC. Martino DJ, et al. Am J Respir Crit Care Med. 2023 Nov 15;208(10):1135-1137. doi: 10.1164/rccm.202306-1025LE. Am J Respir Crit Care Med. 2023. PMID: 37610423 Free article. No abstract available.
Expression of targets of the RNA-binding protein AUF-1 in human airway epithelium indicates its role in cellular senescence and inflammation.
Salvato I, Ricciardi L, Dal Col J, Nigro A, Giurato G, Memoli D, Sellitto A, Lamparelli EP, Crescenzi MA, Vitale M, Vatrella A, Nucera F, Brun P, Caicci F, Dama P, Stiff T, Castellano L, Idrees S, Johansen MD, Faiz A, Wark PA, Hansbro PM, Adcock IM, Caramori G, Stellato C. Salvato I, et al. Among authors: hansbro pm. Front Immunol. 2023 Jul 7;14:1192028. doi: 10.3389/fimmu.2023.1192028. eCollection 2023. Front Immunol. 2023. PMID: 37483631 Free PMC article.
Publisher Correction: Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon.
Ryan TAJ, Hooftman A, Rehill AM, Johansen MD, O' Brien EC, Toller-Kawahisa JE, Wilk MM, Day EA, Weiss HJ, Sarvari P, Vozza EG, Schramm F, Peace CG, Zotta A, Miemczyk S, Nalkurthi C, Hansbro NG, McManus G, O'Doherty L, Gargan S, Long A, Dunne J, Cheallaigh CN, Conlon N, Carty M, Fallon PG, Mills KHG, Creagh EM, O' Donnell JS, Hertzog PJ, Hansbro PM, McLoughlin RM, Wygrecka M, Preston RJS, Zasłona Z, O'Neill LAJ. Ryan TAJ, et al. Among authors: hansbro pm, hansbro ng. Nat Commun. 2023 Jul 20;14(1):4374. doi: 10.1038/s41467-023-40034-1. Nat Commun. 2023. PMID: 37474527 Free PMC article. No abstract available.
Zerumbone-incorporated liquid crystalline nanoparticles inhibit proliferation and migration of non-small-cell lung cancer in vitro.
Manandhar B, Paudel KR, Clarence DD, De Rubis G, Madheswaran T, Panneerselvam J, Zacconi FC, Williams KA, Pont LG, Warkiani ME, MacLoughlin R, Oliver BG, Gupta G, Singh SK, Chellappan DK, Hansbro PM, Dua K. Manandhar B, et al. Naunyn Schmiedebergs Arch Pharmacol. 2024 Jan;397(1):343-356. doi: 10.1007/s00210-023-02603-5. Epub 2023 Jul 13. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 37439806 Free PMC article.
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon.
Ryan TAJ, Hooftman A, Rehill AM, Johansen MD, Brien ECO, Toller-Kawahisa JE, Wilk MM, Day EA, Weiss HJ, Sarvari P, Vozza EG, Schramm F, Peace CG, Zotta A, Miemczyk S, Nalkurthi C, Hansbro NG, McManus G, O'Doherty L, Gargan S, Long A, Dunne J, Cheallaigh CN, Conlon N, Carty M, Fallon PG, Mills KHG, Creagh EM, Donnell JSO, Hertzog PJ, Hansbro PM, McLoughlin RM, Wygrecka M, Preston RJS, Zasłona Z, O'Neill LAJ. Ryan TAJ, et al. Among authors: hansbro pm, hansbro ng. Nat Commun. 2023 Jun 14;14(1):3513. doi: 10.1038/s41467-023-39174-1. Nat Commun. 2023. PMID: 37316487 Free PMC article.
The Complex Association between COPD and COVID-19.
Awatade NT, Wark PAB, Chan ASL, Mamun SMAA, Mohd Esa NY, Matsunaga K, Rhee CK, Hansbro PM, Sohal SS, On Behalf Of The Asian Pacific Society Of Respirology Apsr Copd Assembly. Awatade NT, et al. J Clin Med. 2023 May 31;12(11):3791. doi: 10.3390/jcm12113791. J Clin Med. 2023. PMID: 37297985 Free PMC article. Review.
Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease.
Kapellos TS, Baßler K, Fujii W, Nalkurthi C, Schaar AC, Bonaguro L, Pecht T, Galvao I, Agrawal S, Saglam A, Dudkin E, Frishberg A, de Domenico E, Horne A, Donovan C, Kim RY, Gallego-Ortega D, Gillett TE, Ansari M, Schulte-Schrepping J, Offermann N, Antignano I, Sivri B, Lu W, Eapen MS, van Uelft M, Osei-Sarpong C, van den Berge M, Donker HC, Groen HJM, Sohal SS, Klein J, Schreiber T, Feißt A, Yildirim AÖ, Schiller HB, Nawijn MC, Becker M, Händler K, Beyer M, Capasso M, Ulas T, Hasenauer J, Pizarro C, Theis FJ, Hansbro PM, Skowasch D, Schultze JL. Kapellos TS, et al. Cell Rep. 2023 Jun 27;42(6):112525. doi: 10.1016/j.celrep.2023.112525. Epub 2023 May 26. Cell Rep. 2023. PMID: 37243592 Free PMC article.
Advanced models for respiratory disease and drug studies.
Shrestha J, Paudel KR, Nazari H, Dharwal V, Bazaz SR, Johansen MD, Dua K, Hansbro PM, Warkiani ME. Shrestha J, et al. Med Res Rev. 2023 Sep;43(5):1470-1503. doi: 10.1002/med.21956. Epub 2023 Apr 29. Med Res Rev. 2023. PMID: 37119028 Free PMC article. Review.
Development of a novel angiotensin converting enzyme 2 stimulator with broad implications in SARS-CoV2 and type 1 diabetes.
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