Hastings ML - Search Results

1

Direct Delivery of Antisense Oligonucleotides to the Middle and Inner Ear Improves Hearing and Balance in Usher Mice.

Lentz JJ, Pan B, Ponnath A, Tran CM, Nist-Lund C, Galvin A, Goldberg H, Robillard KN, Jodelka FM, Farris HE, Huang J, Chen T, Zhu H, Zhou W, Rigo F, Hastings ML, Géléoc GSG. Lentz JJ, et al. Among authors: hastings ml. Mol Ther. 2020 Dec 2;28(12):2662-2676. doi: 10.1016/j.ymthe.2020.08.002. Epub 2020 Aug 5. Mol Ther. 2020. PMID: 32818431 Free PMC article.

2

Tetracyclines that promote SMN2 exon 7 splicing as therapeutics for spinal muscular atrophy.

Hastings ML, Berniac J, Liu YH, Abato P, Jodelka FM, Barthel L, Kumar S, Dudley C, Nelson M, Larson K, Edmonds J, Bowser T, Draper M, Higgins P, Krainer AR. Hastings ML, et al. Sci Transl Med. 2009 Nov 4;1(5):5ra12. doi: 10.1126/scitranslmed.3000208. Sci Transl Med. 2009. PMID: 20161659 Free PMC article.

3

A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2.

Jodelka FM, Ebert AD, Duelli DM, Hastings ML. Jodelka FM, et al. Among authors: hastings ml. Hum Mol Genet. 2010 Dec 15;19(24):4906-17. doi: 10.1093/hmg/ddq425. Epub 2010 Sep 30. Hum Mol Genet. 2010. PMID: 20884664 Free PMC article.

4

Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness.

Lentz JJ, Jodelka FM, Hinrich AJ, McCaffrey KE, Farris HE, Spalitta MJ, Bazan NG, Duelli DM, Rigo F, Hastings ML. Lentz JJ, et al. Among authors: hastings ml. Nat Med. 2013 Mar;19(3):345-50. doi: 10.1038/nm.3106. Epub 2013 Feb 4. Nat Med. 2013. PMID: 23380860 Free PMC article.

5

SCRIB and PUF60 are primary drivers of the multisystemic phenotypes of the 8q24.3 copy-number variant.

Dauber A, Golzio C, Guenot C, Jodelka FM, Kibaek M, Kjaergaard S, Leheup B, Martinet D, Nowaczyk MJ, Rosenfeld JA, Zeesman S, Zunich J, Beckmann JS, Hirschhorn JN, Hastings ML, Jacquemont S, Katsanis N. Dauber A, et al. Among authors: hastings ml. Am J Hum Genet. 2013 Nov 7;93(5):798-811. doi: 10.1016/j.ajhg.2013.09.010. Epub 2013 Oct 17. Am J Hum Genet. 2013. PMID: 24140112 Free PMC article.

6

Targeting SR proteins improves SMN expression in spinal muscular atrophy cells.

Wee CD, Havens MA, Jodelka FM, Hastings ML. Wee CD, et al. Among authors: hastings ml. PLoS One. 2014 Dec 15;9(12):e115205. doi: 10.1371/journal.pone.0115205. eCollection 2014. PLoS One. 2014. PMID: 25506695 Free PMC article.

7

Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides.

Hinrich AJ, Jodelka FM, Chang JL, Brutman D, Bruno AM, Briggs CA, James BD, Stutzmann GE, Bennett DA, Miller SA, Rigo F, Marr RA, Hastings ML. Hinrich AJ, et al. Among authors: hastings ml. EMBO Mol Med. 2016 Apr 1;8(4):328-45. doi: 10.15252/emmm.201505846. EMBO Mol Med. 2016. PMID: 26902204 Free PMC article.

8

Antisense oligonucleotides delivered to the amniotic cavity in utero modulate gene expression in the postnatal mouse.

Depreux FF, Wang L, Jiang H, Jodelka FM, Rosencrans RF, Rigo F, Lentz JJ, Brigande JV, Hastings ML. Depreux FF, et al. Among authors: hastings ml. Nucleic Acids Res. 2016 Nov 16;44(20):9519-9529. doi: 10.1093/nar/gkw867. Epub 2016 Sep 28. Nucleic Acids Res. 2016. PMID: 27683224 Free PMC article.

9

Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c.

Pan B, Askew C, Galvin A, Heman-Ackah S, Asai Y, Indzhykulian AA, Jodelka FM, Hastings ML, Lentz JJ, Vandenberghe LH, Holt JR, Géléoc GS. Pan B, et al. Among authors: hastings ml. Nat Biotechnol. 2017 Mar;35(3):264-272. doi: 10.1038/nbt.3801. Epub 2017 Feb 6. Nat Biotechnol. 2017. PMID: 28165476 Free PMC article.

10

Rescue of peripheral vestibular function in Usher syndrome mice using a splice-switching antisense oligonucleotide.

Vijayakumar S, Depreux FF, Jodelka FM, Lentz JJ, Rigo F, Jones TA, Hastings ML. Vijayakumar S, et al. Among authors: hastings ml. Hum Mol Genet. 2017 Sep 15;26(18):3482-3494. doi: 10.1093/hmg/ddx234. Hum Mol Genet. 2017. PMID: 28633508 Free PMC article.

11

Rescue of Outer Hair Cells with Antisense Oligonucleotides in Usher Mice Is Dependent on Age of Treatment.

Ponnath A, Depreux FF, Jodelka FM, Rigo F, Farris HE, Hastings ML, Lentz JJ. Ponnath A, et al. Among authors: hastings ml. J Assoc Res Otolaryngol. 2018 Feb;19(1):1-16. doi: 10.1007/s10162-017-0640-x. Epub 2017 Oct 12. J Assoc Res Otolaryngol. 2018. PMID: 29027038 Free PMC article.

12

Antisense oligonucleotide therapy rescues disruptions in organization of exploratory movements associated with Usher syndrome type 1C in mice.

Donaldson TN, Jennings KT, Cherep LA, McNeela AM, Depreux FF, Jodelka FM, Hastings ML, Wallace DG. Donaldson TN, et al. Among authors: hastings ml. Behav Brain Res. 2018 Feb 15;338:76-87. doi: 10.1016/j.bbr.2017.10.012. Epub 2017 Oct 14. Behav Brain Res. 2018. PMID: 29037661 Free PMC article.

13

Targeting Amyloid-β Precursor Protein, APP, Splicing with Antisense Oligonucleotides Reduces Toxic Amyloid-β Production.

Chang JL, Hinrich AJ, Roman B, Norrbom M, Rigo F, Marr RA, Norstrom EM, Hastings ML. Chang JL, et al. Among authors: hastings ml. Mol Ther. 2018 Jun 6;26(6):1539-1551. doi: 10.1016/j.ymthe.2018.02.029. Epub 2018 Mar 6. Mol Ther. 2018. PMID: 29628304 Free PMC article.

14

Neurite Collapse and Altered ER Ca²⁺ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation.

Korecka JA, Talbot S, Osborn TM, de Leeuw SM, Levy SA, Ferrari EJ, Moskites A, Atkinson E, Jodelka FM, Hinrich AJ, Hastings ML, Woolf CJ, Hallett PJ, Isacson O. Korecka JA, et al. Among authors: hastings ml. Stem Cell Reports. 2019 Jan 8;12(1):29-41. doi: 10.1016/j.stemcr.2018.11.021. Epub 2018 Dec 27. Stem Cell Reports. 2019. PMID: 30595548 Free PMC article.

15

Antisense Oligonucleotides for the Treatment of Inner Ear Dysfunction.

Hastings ML, Jones TA. Hastings ML, et al. Neurotherapeutics. 2019 Apr;16(2):348-359. doi: 10.1007/s13311-019-00729-0. Neurotherapeutics. 2019. PMID: 30972560 Free PMC article. Review.

16

Fetal gene therapy and pharmacotherapy to treat congenital hearing loss and vestibular dysfunction.

Hastings ML, Brigande JV. Hastings ML, et al. Hear Res. 2020 Sep 1;394:107931. doi: 10.1016/j.heares.2020.107931. Epub 2020 Mar 5. Hear Res. 2020. PMID: 32173115 Free PMC article. Review.

17

Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction.

Wang L, Kempton JB, Jiang H, Jodelka FM, Brigande AM, Dumont RA, Rigo F, Lentz JJ, Hastings ML, Brigande JV. Wang L, et al. Among authors: hastings ml. Nucleic Acids Res. 2020 May 21;48(9):5065-5080. doi: 10.1093/nar/gkaa194. Nucleic Acids Res. 2020. PMID: 32249312 Free PMC article.

18

Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease.

Centa JL, Jodelka FM, Hinrich AJ, Johnson TB, Ochaba J, Jackson M, Duelli DM, Weimer JM, Rigo F, Hastings ML. Centa JL, et al. Among authors: hastings ml. Nat Med. 2020 Sep;26(9):1444-1451. doi: 10.1038/s41591-020-0986-1. Epub 2020 Jul 27. Nat Med. 2020. PMID: 32719489 Free PMC article.

19

Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice.

Korecka JA, Thomas R, Hinrich AJ, Moskites AM, Macbain ZK, Hallett PJ, Isacson O, Hastings ML. Korecka JA, et al. Among authors: hastings ml. Mol Ther Nucleic Acids. 2020 Sep 4;21:623-635. doi: 10.1016/j.omtn.2020.06.027. Epub 2020 Jun 27. Mol Ther Nucleic Acids. 2020. PMID: 32736291 Free PMC article.

20

Corticosteroid sensitization drives opioid addiction.

Carmack SA, Vendruscolo JCM, Adrienne McGinn M, Miranda-Barrientos J, Repunte-Canonigo V, Bosse GD, Mercatelli D, Giorgi FM, Fu Y, Hinrich AJ, Jodelka FM, Ling K, Messing RO, Peterson RT, Rigo F, Edwards S, Sanna PP, Morales M, Hastings ML, Koob GF, Vendruscolo LF. Carmack SA, et al. Among authors: hastings ml. Mol Psychiatry. 2022 May;27(5):2492-2501. doi: 10.1038/s41380-022-01501-1. Epub 2022 Mar 16. Mol Psychiatry. 2022. PMID: 35296810 Free PMC article.

21

Elevating microRNA levels by targeting biogenesis with steric-blocking antisense oligonucleotides.

Havens MA, Hinrich AJ, Rigo F, Hastings ML. Havens MA, et al. Among authors: hastings ml. RNA. 2024 Nov 18;30(12):1543-1553. doi: 10.1261/rna.080021.124. RNA. 2024. PMID: 39255995 Free PMC article.

22

Induction of antagonistic soluble decoy receptor tyrosine kinases by intronic polyA activation.

Vorlová S, Rocco G, Lefave CV, Jodelka FM, Hess K, Hastings ML, Henke E, Cartegni L. Vorlová S, et al. Among authors: hastings ml. Mol Cell. 2011 Sep 16;43(6):927-39. doi: 10.1016/j.molcel.2011.08.009. Mol Cell. 2011. PMID: 21925381 Free PMC article.

23

Splice-switching antisense oligonucleotides as therapeutic drugs.

Havens MA, Hastings ML. Havens MA, et al. Among authors: hastings ml. Nucleic Acids Res. 2016 Aug 19;44(14):6549-63. doi: 10.1093/nar/gkw533. Epub 2016 Jun 10. Nucleic Acids Res. 2016. PMID: 27288447 Free PMC article. Review.

24

Antisense oligonucleotide-mediated correction of CFTR splicing improves chloride secretion in cystic fibrosis patient-derived bronchial epithelial cells.

Michaels WE, Bridges RJ, Hastings ML. Michaels WE, et al. Among authors: hastings ml. Nucleic Acids Res. 2020 Jul 27;48(13):7454-7467. doi: 10.1093/nar/gkaa490. Nucleic Acids Res. 2020. PMID: 32520327 Free PMC article.

25

Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis.

Michaels WE, Pena-Rasgado C, Kotaria R, Bridges RJ, Hastings ML. Michaels WE, et al. Among authors: hastings ml. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2114886119. doi: 10.1073/pnas.2114886119. Proc Natl Acad Sci U S A. 2022. PMID: 35017302 Free PMC article.

26

Targeting Alternative Splicing for Therapeutic Interventions.

Centa JL, Hastings ML. Centa JL, et al. Among authors: hastings ml. Methods Mol Biol. 2022;2537:21-36. doi: 10.1007/978-1-0716-2521-7_2. Methods Mol Biol. 2022. PMID: 35895256

27

Systematic deletion of symmetrical CFTR exons reveals new therapeutic targets for exon skipping antisense oligonucleotides.

Pena-Rasgado C, Rodriguez-Manriquez E, Dundr M, Bridges RJ, Hastings ML, Michaels WE. Pena-Rasgado C, et al. Among authors: hastings ml. NAR Mol Med. 2024 Nov 6;1(4):ugae017. doi: 10.1093/narmme/ugae017. eCollection 2024 Oct. NAR Mol Med. 2024. PMID: 39582793 Free PMC article.

28

Targeting RNA splicing for disease therapy.

Havens MA, Duelli DM, Hastings ML. Havens MA, et al. Among authors: hastings ml. Wiley Interdiscip Rev RNA. 2013 May-Jun;4(3):247-66. doi: 10.1002/wrna.1158. Epub 2013 Mar 19. Wiley Interdiscip Rev RNA. 2013. PMID: 23512601 Free PMC article. Review.

29

Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson's disease patient fibroblasts.

Korecka JA, Thomas R, Christensen DP, Hinrich AJ, Ferrari EJ, Levy SA, Hastings ML, Hallett PJ, Isacson O. Korecka JA, et al. Among authors: hastings ml. Hum Mol Genet. 2019 Oct 1;28(19):3232-3243. doi: 10.1093/hmg/ddz126. Hum Mol Genet. 2019. PMID: 31261377 Free PMC article.

30

Functions of SR proteins in the U12-dependent AT-AC pre-mRNA splicing pathway.

Hastings ML, Krainer AR. Hastings ML, et al. RNA. 2001 Mar;7(3):471-82. doi: 10.1017/s1355838201002552. RNA. 2001. PMID: 11333026 Free PMC article.

31

Pre-mRNA splicing in the new millennium.

Hastings ML, Krainer AR. Hastings ML, et al. Curr Opin Cell Biol. 2001 Jun;13(3):302-9. doi: 10.1016/s0955-0674(00)00212-x. Curr Opin Cell Biol. 2001. PMID: 11343900 Review.

32

Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2.

Cartegni L, Hastings ML, Calarco JA, de Stanchina E, Krainer AR. Cartegni L, et al. Among authors: hastings ml. Am J Hum Genet. 2006 Jan;78(1):63-77. doi: 10.1086/498853. Epub 2005 Nov 16. Am J Hum Genet. 2006. PMID: 16385450 Free PMC article.

33

Alternative splicing regulation by interaction of phosphatase PP2Cgamma with nucleic acid-binding protein YB-1.

Allemand E, Hastings ML, Murray MV, Myers MP, Krainer AR. Allemand E, et al. Among authors: hastings ml. Nat Struct Mol Biol. 2007 Jul;14(7):630-8. doi: 10.1038/nsmb1257. Epub 2007 Jun 17. Nat Struct Mol Biol. 2007. PMID: 17572683

34

Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65).

Hastings ML, Allemand E, Duelli DM, Myers MP, Krainer AR. Hastings ML, et al. PLoS One. 2007 Jun 20;2(6):e538. doi: 10.1371/journal.pone.0000538. PLoS One. 2007. PMID: 17579712 Free PMC article.

35

Dual-specificity splice sites function alternatively as 5' and 3' splice sites.

Zhang C, Hastings ML, Krainer AR, Zhang MQ. Zhang C, et al. Among authors: hastings ml. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15028-33. doi: 10.1073/pnas.0703773104. Epub 2007 Sep 11. Proc Natl Acad Sci U S A. 2007. PMID: 17848517 Free PMC article.

36

Differential 3' splice site recognition of SMN1 and SMN2 transcripts by U2AF and U2 snRNP.

Martins de Araújo M, Bonnal S, Hastings ML, Krainer AR, Valcárcel J. Martins de Araújo M, et al. Among authors: hastings ml. RNA. 2009 Apr;15(4):515-23. doi: 10.1261/rna.1273209. Epub 2009 Feb 25. RNA. 2009. PMID: 19244360 Free PMC article.

37

Selective release of microRNA species from normal and malignant mammary epithelial cells.

Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM. Pigati L, et al. Among authors: hastings ml. PLoS One. 2010 Oct 20;5(10):e13515. doi: 10.1371/journal.pone.0013515. PLoS One. 2010. PMID: 20976003 Free PMC article.

38

Plasma components affect accuracy of circulating cancer-related microRNA quantitation.

Kim DJ, Linnstaedt S, Palma J, Park JC, Ntrivalas E, Kwak-Kim JY, Gilman-Sachs A, Beaman K, Hastings ML, Martin JN, Duelli DM. Kim DJ, et al. Among authors: hastings ml. J Mol Diagn. 2012 Jan;14(1):71-80. doi: 10.1016/j.jmoldx.2011.09.002. Epub 2011 Nov 30. J Mol Diagn. 2012. PMID: 22154918 Free PMC article.

39

Biogenesis of mammalian microRNAs by a non-canonical processing pathway.

Havens MA, Reich AA, Duelli DM, Hastings ML. Havens MA, et al. Among authors: hastings ml. Nucleic Acids Res. 2012 May;40(10):4626-40. doi: 10.1093/nar/gks026. Epub 2012 Jan 23. Nucleic Acids Res. 2012. PMID: 22270084 Free PMC article.

40

MicroRNAs are exported from malignant cells in customized particles.

Palma J, Yaddanapudi SC, Pigati L, Havens MA, Jeong S, Weiner GA, Weimer KM, Stern B, Hastings ML, Duelli DM. Palma J, et al. Among authors: hastings ml. Nucleic Acids Res. 2012 Oct;40(18):9125-38. doi: 10.1093/nar/gks656. Epub 2012 Jul 5. Nucleic Acids Res. 2012. PMID: 22772984 Free PMC article.

41

Sensitive PCR-based quantitation of cell-free circulating microRNAs.

Hastings ML, Palma J, Duelli DM. Hastings ML, et al. Methods. 2012 Oct;58(2):144-50. doi: 10.1016/j.ymeth.2012.07.026. Epub 2012 Aug 3. Methods. 2012. PMID: 22884953 Free PMC article.

42

Authors' reply.

Duelli DM, Palma J, Beaman K, Hastings ML, Kwak-Kim J, Linnstaedt S, Park JC, Kim DJ. Duelli DM, et al. Among authors: hastings ml. J Mol Diagn. 2013 Jan;15(1):138-9. J Mol Diagn. 2013. PMID: 23390637 No abstract available.

43

Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis.

Geraets RD, Koh Sy, Hastings ML, Kielian T, Pearce DA, Weimer JM. Geraets RD, et al. Among authors: hastings ml. Orphanet J Rare Dis. 2016 Apr 16;11:40. doi: 10.1186/s13023-016-0414-2. Orphanet J Rare Dis. 2016. PMID: 27083890 Free PMC article. Review.

44

A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD.

Parnell SC, Magenheimer BS, Maser RL, Pavlov TS, Havens MA, Hastings ML, Jackson SF, Ward CJ, Peterson KR, Staruschenko A, Calvet JP. Parnell SC, et al. Among authors: hastings ml. Hum Mol Genet. 2018 Oct 1;27(19):3313-3324. doi: 10.1093/hmg/ddy223. Hum Mol Genet. 2018. PMID: 29931260 Free PMC article.

45

Searching for novel biomarkers using a mouse model of CLN3-Batten disease.

Timm D, Cain JT, Geraets RD, White KA, Koh SY, Kielian T, Pearce DA, Hastings ML, Weimer JM. Timm D, et al. Among authors: hastings ml. PLoS One. 2018 Aug 7;13(8):e0201470. doi: 10.1371/journal.pone.0201470. eCollection 2018. PLoS One. 2018. PMID: 30086172 Free PMC article.

46

Identification of SRSF10 as a regulator of SMN2 ISS-N1.

Frederiksen SB, Holm LL, Larsen MR, Doktor TK, Andersen HS, Hastings ML, Hua Y, Krainer AR, Andresen BS. Frederiksen SB, et al. Among authors: hastings ml. Hum Mutat. 2021 Mar;42(3):246-260. doi: 10.1002/humu.24149. Epub 2020 Dec 16. Hum Mutat. 2021. PMID: 33300159 Free PMC article.

47

Expression of the thyroid hormone receptor gene, erbAalpha, in B lymphocytes: alternative mRNA processing is independent of differentiation but correlates with antisense RNA levels.

Hastings ML, Milcarek C, Martincic K, Peterson ML, Munroe SH. Hastings ML, et al. Nucleic Acids Res. 1997 Nov 1;25(21):4296-300. doi: 10.1093/nar/25.21.4296. Nucleic Acids Res. 1997. PMID: 9336460 Free PMC article.

48

An LKB1 AT-AC intron mutation causes Peutz-Jeghers syndrome via splicing at noncanonical cryptic splice sites.

Hastings ML, Resta N, Traum D, Stella A, Guanti G, Krainer AR. Hastings ML, et al. Nat Struct Mol Biol. 2005 Jan;12(1):54-9. doi: 10.1038/nsmb873. Epub 2004 Dec 19. Nat Struct Mol Biol. 2005. PMID: 15608654

49

Comprehensive splice-site analysis using comparative genomics.

Sheth N, Roca X, Hastings ML, Roeder T, Krainer AR, Sachidanandam R. Sheth N, et al. Among authors: hastings ml. Nucleic Acids Res. 2006;34(14):3955-67. doi: 10.1093/nar/gkl556. Epub 2006 Aug 12. Nucleic Acids Res. 2006. PMID: 16914448 Free PMC article.

50

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

Bruno AM, Huang JY, Bennett DA, Marr RA, Hastings ML, Stutzmann GE. Bruno AM, et al. Among authors: hastings ml. Neurobiol Aging. 2012 May;33(5):1001.e1-6. doi: 10.1016/j.neurobiolaging.2011.03.011. Epub 2011 Apr 30. Neurobiol Aging. 2012. PMID: 21531043 Free PMC article.

51

Drosha promotes splicing of a pre-microRNA-like alternative exon.

Havens MA, Reich AA, Hastings ML. Havens MA, et al. Among authors: hastings ml. PLoS Genet. 2014 May 1;10(5):e1004312. doi: 10.1371/journal.pgen.1004312. eCollection 2014 May. PLoS Genet. 2014. PMID: 24786770 Free PMC article.

52

A purine-rich intronic element enhances alternative splicing of thyroid hormone receptor mRNA.

Hastings ML, Wilson CM, Munroe SH. Hastings ML, et al. RNA. 2001 Jun;7(6):859-74. doi: 10.1017/s1355838201002084. RNA. 2001. PMID: 11421362 Free PMC article.

53

Ensemble analysis of primary microRNA structure reveals an extensive capacity to deform near the Drosha cleavage site.

Quarles KA, Sahu D, Havens MA, Forsyth ER, Wostenberg C, Hastings ML, Showalter SA. Quarles KA, et al. Among authors: hastings ml. Biochemistry. 2013 Feb 5;52(5):795-807. doi: 10.1021/bi301452a. Epub 2013 Jan 18. Biochemistry. 2013. PMID: 23305493 Free PMC article.

54

Expression and purification of splicing proteins from mammalian cells.

Allemand E, Hastings ML. Allemand E, et al. Among authors: hastings ml. Methods Mol Biol. 2014;1126:205-16. doi: 10.1007/978-1-62703-980-2_16. Methods Mol Biol. 2014. PMID: 24549667

55

A big score for RNA.

Hastings ML. Hastings ML. RNA. 2015 Apr;21(4):634-5. doi: 10.1261/rna.050757.115. RNA. 2015. PMID: 25780170 Free PMC article. No abstract available.

56

An exonic splicing enhancer within a bidirectional coding sequence regulates alternative splicing of an antisense mRNA.

Salato VK, Rediske NW, Zhang C, Hastings ML, Munroe SH. Salato VK, et al. Among authors: hastings ml. RNA Biol. 2010 Mar-Apr;7(2):179-90. doi: 10.4161/rna.7.2.11182. Epub 2010 Mar 8. RNA Biol. 2010. PMID: 20200494 Free PMC article.

57

RNA localization and co-translational interactions control RAB13 GTPase function and cell migration.

Moissoglu K, Stueland M, Gasparski AN, Wang T, Jenkins LM, Hastings ML, Mili S. Moissoglu K, et al. Among authors: hastings ml. EMBO J. 2020 Nov 2;39(21):e104958. doi: 10.15252/embj.2020104958. Epub 2020 Sep 18. EMBO J. 2020. PMID: 32946136 Free PMC article.

58

Post-transcriptional regulation of thyroid hormone receptor expression by cis-acting sequences and a naturally occurring antisense RNA.

Hastings ML, Ingle HA, Lazar MA, Munroe SH. Hastings ML, et al. J Biol Chem. 2000 Apr 14;275(15):11507-13. doi: 10.1074/jbc.275.15.11507. J Biol Chem. 2000. PMID: 10753970 Free article.

59

The effects of human milk fortification on nutrients and milk properties.

Donovan R, Kelly SG, Prazad P, Talaty PN, Lefaiver C, Hastings ML, Everly DN. Donovan R, et al. Among authors: hastings ml. J Perinatol. 2017 Jan;37(1):42-48. doi: 10.1038/jp.2016.166. Epub 2016 Oct 6. J Perinatol. 2017. PMID: 27711042

60

Modulating NLRP3 splicing with antisense oligonucleotides to control pathological inflammation.

Klein R, Onyuru J, Viera EM, Putnam CD, Hoffman HM, Hastings ML. Klein R, et al. Among authors: hastings ml. bioRxiv [Preprint]. 2024 Sep 6:2024.09.06.611206. doi: 10.1101/2024.09.06.611206. bioRxiv. 2024. PMID: 39282364 Free PMC article. Preprint.

61

RNA therapeutics.

Hastings ML, Krainer AR. Hastings ML, et al. RNA. 2023 Apr;29(4):393-395. doi: 10.1261/rna.079626.123. RNA. 2023. PMID: 36928165 Free PMC article.

62

Viral-like TLR3 induction of cytokine networks and α-synuclein are reduced by complement C3 blockade in mouse brain.

Thomas R, Connolly KJ, Brekk OR, Hinrich AJ, Hastings ML, Isacson O, Hallett PJ. Thomas R, et al. Among authors: hastings ml. Sci Rep. 2023 Sep 13;13(1):15164. doi: 10.1038/s41598-023-41240-z. Sci Rep. 2023. PMID: 37704739 Free PMC article.

63

Protracted CLN3 Batten disease in mice that genetically model an exon-skipping therapeutic approach.

Centa JL, Stratton MP, Pratt MA, Osterlund Oltmanns JR, Wallace DG, Miller SA, Weimer JM, Hastings ML. Centa JL, et al. Among authors: hastings ml. Mol Ther Nucleic Acids. 2023 Jun 3;33:15-27. doi: 10.1016/j.omtn.2023.05.025. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37359347 Free PMC article.

64

Spatial Disorientation Under Dark Conditions Across Development in an Alzheimer's Disease Mouse Model.

Blackwell AA, Jodelka FM, Lake RI, Hastings ML, Wallace DG. Blackwell AA, et al. Among authors: hastings ml. Neuroscience. 2023 Feb 10;511:53-69. doi: 10.1016/j.neuroscience.2022.12.012. Epub 2022 Dec 29. Neuroscience. 2023. PMID: 36587866

65

A Case of a Methicillin-Resistant Staphylococcus Aureus Retropharyngeal Abscess With Mediastinal Extension in an 11-Month-Old Girl.

Shanti RM, Hastings ML, Patel S, Yeoh MS. Shanti RM, et al. Among authors: hastings ml. J Oral Maxillofac Surg. 2016 Apr;74(4):747-53. doi: 10.1016/j.joms.2015.10.005. Epub 2015 Oct 23. J Oral Maxillofac Surg. 2016. PMID: 26541226

66

Effects of sex, age, reading ability, socioeconomic level, and display position on a measure of spatial relations in children.

Davol SH, Hastings ML. Davol SH, et al. Among authors: hastings ml. Percept Mot Skills. 1967 Apr;24(2):375-87. doi: 10.2466/pms.1967.24.2.375. Percept Mot Skills. 1967. PMID: 6040210 No abstract available.

67

Effect of age, sex, and speed of rotation on rotary pursuit performance by young children.

Davol SH, Hastings ML, Klein DA. Davol SH, et al. Among authors: hastings ml. Percept Mot Skills. 1965 Oct;21(2):351-7. doi: 10.2466/pms.1965.21.2.351. Percept Mot Skills. 1965. PMID: 5848898 No abstract available.

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