Hirasawa A - Search Results

1

ATM: Functions of ATM Kinase and Its Relevance to Hereditary Tumors.

Ueno S, Sudo T, Hirasawa A. Ueno S, et al. Among authors: hirasawa a. Int J Mol Sci. 2022 Jan 4;23(1):523. doi: 10.3390/ijms23010523. Int J Mol Sci. 2022. PMID: 35008949 Free PMC article. Review.

2

Relationship between ABCF2 expression and response to chemotherapy or prognosis in clear cell adenocarcinoma of the ovary.

Tsuda H, Ito K, Yaegashi N, Hirasawa A, Sudo T, Kita T, Terai Y, Kigawa J, Sugiyama T, Aoki D. Tsuda H, et al. Among authors: hirasawa a. Int J Gynecol Cancer. 2010 Jul;20(5):794-7. doi: 10.1111/igc.0b013e3181a835fc. Int J Gynecol Cancer. 2010. PMID: 20973270

3

Molecular Features and Clinical Management of Hereditary Gynecological Cancers.

Ueki A, Hirasawa A. Ueki A, et al. Among authors: hirasawa a. Int J Mol Sci. 2020 Dec 14;21(24):9504. doi: 10.3390/ijms21249504. Int J Mol Sci. 2020. PMID: 33327492 Free PMC article. Review.

4

Germline Whole-Gene Deletion of FH Diagnosed from Tumor Profiling.

Ueki A, Sugano K, Misu K, Aimono E, Nakamura K, Tanishima S, Tanaka N, Mikami S, Hirasawa A, Ando M, Yoshida T, Oya M, Nishihara H, Kosaki K. Ueki A, et al. Among authors: hirasawa a. Int J Mol Sci. 2021 Jul 26;22(15):7962. doi: 10.3390/ijms22157962. Int J Mol Sci. 2021. PMID: 34360727 Free PMC article.

5

Hereditary pancreatic cancer.

Abe K, Kitago M, Kitagawa Y, Hirasawa A. Abe K, et al. Among authors: hirasawa a. Int J Clin Oncol. 2021 Oct;26(10):1784-1792. doi: 10.1007/s10147-021-02015-6. Epub 2021 Sep 2. Int J Clin Oncol. 2021. PMID: 34476650 Free PMC article. Review.

6

Homologous Recombination Deficiencies and Hereditary Tumors.

Yamamoto H, Hirasawa A. Yamamoto H, et al. Among authors: hirasawa a. Int J Mol Sci. 2021 Dec 29;23(1):348. doi: 10.3390/ijms23010348. Int J Mol Sci. 2021. PMID: 35008774 Free PMC article. Review.

7

Hereditary gynecologic tumors and precision cancer medicine.

Ogawa C, Hirasawa A, Ida N, Nakamura K, Masuyama H. Ogawa C, et al. Among authors: hirasawa a. J Obstet Gynaecol Res. 2022 May;48(5):1076-1090. doi: 10.1111/jog.15197. Epub 2022 Feb 28. J Obstet Gynaecol Res. 2022. PMID: 35229413 Review.

8

[The Cooperation with Medical Staff, Medical Staff and Patients, and Patients and Their Families in Cancer Precision Medicine].

Hirasawa A. Hirasawa A. Gan To Kagaku Ryoho. 2022 Sep;49(9):1000-1001. Gan To Kagaku Ryoho. 2022. PMID: 36156025 Japanese.

9

Monitoring ligand-mediated internalization of G protein-coupled receptor as a novel pharmacological approach.

Fukunaga S, Setoguchi S, Hirasawa A, Tsujimoto G. Fukunaga S, et al. Among authors: hirasawa a. Life Sci. 2006 Dec 3;80(1):17-23. doi: 10.1016/j.lfs.2006.08.022. Epub 2006 Aug 25. Life Sci. 2006. PMID: 16978657

10

Flow cytometry-based binding assay for GPR40 (FFAR1; free fatty acid receptor 1).

Hara T, Hirasawa A, Sun Q, Koshimizu TA, Itsubo C, Sadakane K, Awaji T, Tsujimoto G. Hara T, et al. Among authors: hirasawa a. Mol Pharmacol. 2009 Jan;75(1):85-91. doi: 10.1124/mol.108.052225. Epub 2008 Oct 16. Mol Pharmacol. 2009. PMID: 18927207

11

New frontiers in gut nutrient sensor research: free fatty acid sensing in the gastrointestinal tract.

Miyauchi S, Hirasawa A, Ichimura A, Hara T, Tsujimoto G. Miyauchi S, et al. Among authors: hirasawa a. J Pharmacol Sci. 2010;112(1):19-24. doi: 10.1254/jphs.09r09fm. J Pharmacol Sci. 2010. PMID: 20093784 Free article. Review.

12

Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders.

Hara T, Hirasawa A, Ichimura A, Kimura I, Tsujimoto G. Hara T, et al. Among authors: hirasawa a. J Pharm Sci. 2011 Sep;100(9):3594-601. doi: 10.1002/jps.22639. Epub 2011 May 25. J Pharm Sci. 2011. PMID: 21618241 Review.

13

Relationship between DNA Mismatch Repair Deficiency and Endometrial Cancer.

Masuda K, Banno K, Yanokura M, Kobayashi Y, Kisu I, Ueki A, Ono A, Asahara N, Nomura H, Hirasawa A, Susumu N, Aoki D. Masuda K, et al. Among authors: hirasawa a. Mol Biol Int. 2011;2011:256063. doi: 10.4061/2011/256063. Epub 2011 Dec 8. Mol Biol Int. 2011. PMID: 22175017 Free PMC article.

14

Japan Society of Clinical Oncology provisional clinical opinion for the diagnosis and use of immunotherapy in patients with deficient DNA mismatch repair tumors, cooperated by Japanese Society of Medical Oncology, First Edition.

Mishima S, Taniguchi H, Akagi K, Baba E, Fujiwara Y, Hirasawa A, Ikeda M, Maeda O, Muro K, Nishihara H, Nishiyama H, Takano T, Tsuchihara K, Yatabe Y, Kodera Y, Yoshino T. Mishima S, et al. Among authors: hirasawa a. Int J Clin Oncol. 2020 Feb;25(2):217-239. doi: 10.1007/s10147-019-01498-8. Epub 2019 Jul 8. Int J Clin Oncol. 2020. PMID: 31286289 Free PMC article.

15

Molecular Mechanism of Apoptosis by Amyloid β-Protein Fibrils Formed on Neuronal Cells.

Takada E, Okubo K, Yano Y, Iida K, Someda M, Hirasawa A, Yonehara S, Matsuzaki K. Takada E, et al. Among authors: hirasawa a. ACS Chem Neurosci. 2020 Mar 4;11(5):796-805. doi: 10.1021/acschemneuro.0c00011. Epub 2020 Feb 14. ACS Chem Neurosci. 2020. PMID: 32056421

16

Retrospective evaluation of risk-reducing salpingo-oophorectomy for BRCA1/2 pathogenic variant carriers among a cohort study in a single institution.

Kobayashi Y, Hirasawa A, Chiyoda T, Ueki A, Masuda K, Misu K, Kawaida M, Hayashi S, Kataoka F, Banno K, Kosaki K, Aoki D. Kobayashi Y, et al. Among authors: hirasawa a. Jpn J Clin Oncol. 2021 Feb 8;51(2):213-217. doi: 10.1093/jjco/hyaa173. Jpn J Clin Oncol. 2021. PMID: 33037428

17

Familial pancreatic cancer with PALB2 and NBN pathogenic variants: a case report.

Abe K, Ueki A, Urakawa Y, Kitago M, Yoshihama T, Nanki Y, Kitagawa Y, Aoki D, Kosaki K, Hirasawa A. Abe K, et al. Among authors: hirasawa a. Hered Cancer Clin Pract. 2021 Jan 7;19(1):5. doi: 10.1186/s13053-020-00160-z. Hered Cancer Clin Pract. 2021. PMID: 33413558 Free PMC article.

18

Germline multigene panel testing revealed a BRCA2 pathogenic variant in a patient with suspected Lynch syndrome.

Yoshihama T, Hirasawa A, Sugano K, Yoshida T, Ushiama M, Ueki A, Akahane T, Nanki Y, Sakai K, Makabe T, Yamagami W, Susumu N, Kameyama K, Kosaki K, Aoki D. Yoshihama T, et al. Among authors: hirasawa a. Int Cancer Conf J. 2020 Oct 9;10(1):6-10. doi: 10.1007/s13691-020-00449-9. eCollection 2021 Jan. Int Cancer Conf J. 2020. PMID: 33489693 Free PMC article.

19

Best practices for the extraction of genomic DNA from formalin-fixed paraffin-embedded tumor tissue for cancer genomic profiling tests.

Inoue H, Tomida S, Horiguchi S, Kato H, Matsuoka H, Sanehira E, Matsuoka M, Yanai H, Hirasawa A, Toyooka S. Inoue H, et al. Among authors: hirasawa a. Pathol Int. 2021 May;71(5):360-364. doi: 10.1111/pin.13086. Epub 2021 Mar 3. Pathol Int. 2021. PMID: 33657250 Free article.

20

SMAD4 Germline Pathogenic Variant-Related Gastric Juvenile Polyposis with Adenocarcinoma Treated with Laparoscopic Total Gastrectomy: A Case Report.

Sakurai Y, Kikuchi S, Shigeyasu K, Kakiuchi Y, Tanaka T, Umeda H, Sakamoto M, Takeda S, Yano S, Futagawa M, Kato F, Sogawa R, Yamamoto H, Kuroda S, Kondo Y, Teraishi F, Kishimoto H, Nishizaki M, Kagawa S, Hirasawa A, Fujiwara T. Sakurai Y, et al. Among authors: hirasawa a. Am J Case Rep. 2021 Jun 18;22:e932241. doi: 10.12659/AJCR.932241. Am J Case Rep. 2021. PMID: 34143765 Free PMC article.

21

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2020 for the Clinical Practice of Hereditary Colorectal Cancer.

Tomita N, Ishida H, Tanakaya K, Yamaguchi T, Kumamoto K, Tanaka T, Hinoi T, Miyakura Y, Hasegawa H, Takayama T, Ishikawa H, Nakajima T, Chino A, Shimodaira H, Hirasawa A, Nakayama Y, Sekine S, Tamura K, Akagi K, Kawasaki Y, Kobayashi H, Arai M, Itabashi M, Hashiguchi Y, Sugihara K; Japanese Society for Cancer of the Colon, Rectum. Tomita N, et al. Among authors: hirasawa a. Int J Clin Oncol. 2021 Aug;26(8):1353-1419. doi: 10.1007/s10147-021-01881-4. Epub 2021 Jun 29. Int J Clin Oncol. 2021. PMID: 34185173 Free PMC article.

22

Liquid Biopsy Revealed HBOC Pedigree and Led to Medical Management Among the Relatives.

Ogawa C, Hirasawa A, Sogawa R, Hasuoka K, Tomida S, Futagawa M, Urakawa Y, Kochi M, Yamamoto H, Nakamura K, Masuyama H. Ogawa C, et al. Among authors: hirasawa a. Acta Med Okayama. 2022 Aug;76(4):479-483. doi: 10.18926/AMO/63908. Acta Med Okayama. 2022. PMID: 36123164 Free article.

23

Association of HNPCC and endometrial cancers.

Banno K, Susumu N, Yanokura M, Hirao T, Iwata T, Hirasawa A, Aoki D, Sugano K, Nozawa S. Banno K, et al. Among authors: hirasawa a. Int J Clin Oncol. 2004 Aug;9(4):262-9. doi: 10.1007/s10147-004-0402-8. Int J Clin Oncol. 2004. PMID: 15375702 Review.

24

Structure-activity relationships of GPR120 agonists based on a docking simulation.

Sun Q, Hirasawa A, Hara T, Kimura I, Adachi T, Awaji T, Ishiguro M, Suzuki T, Miyata N, Tsujimoto G. Sun Q, et al. Among authors: hirasawa a. Mol Pharmacol. 2010 Nov;78(5):804-10. doi: 10.1124/mol.110.066324. Epub 2010 Aug 4. Mol Pharmacol. 2010. PMID: 20685848

25

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human.

Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, Takeuchi M, Ozawa K, Tauber M, Maffeis C, Morandi A, Buzzetti R, Elliott P, Pouta A, Jarvelin MR, Körner A, Kiess W, Pigeyre M, Caiazzo R, Van Hul W, Van Gaal L, Horber F, Balkau B, Lévy-Marchal C, Rouskas K, Kouvatsi A, Hebebrand J, Hinney A, Scherag A, Pattou F, Meyre D, Koshimizu TA, Wolowczuk I, Tsujimoto G, Froguel P. Ichimura A, et al. Among authors: hirasawa a. Nature. 2012 Feb 19;483(7389):350-4. doi: 10.1038/nature10798. Nature. 2012. PMID: 22343897 Free article.

26

Treatment of intermittent hypoxia increases phosphorylated tau in the hippocampus via biological processes common to aging.

Yagishita S, Suzuki S, Yoshikawa K, Iida K, Hirata A, Suzuki M, Takashima A, Maruyama K, Hirasawa A, Awaji T. Yagishita S, et al. Among authors: hirasawa a. Mol Brain. 2017 Jan 5;10(1):2. doi: 10.1186/s13041-016-0282-7. Mol Brain. 2017. PMID: 28057021 Free PMC article.

27

Japan society of clinical oncology/Japanese society of medical oncology-led clinical recommendations on the diagnosis and use of tropomyosin receptor kinase inhibitors in adult and pediatric patients with neurotrophic receptor tyrosine kinase fusion-positive advanced solid tumors, cooperated by the Japanese society of pediatric hematology/oncology.

Naito Y, Mishima S, Akagi K, Igarashi A, Ikeda M, Okano S, Kato S, Takano T, Tsuchihara K, Terashima K, Nishihara H, Nishiyama H, Hiyama E, Hirasawa A, Hosoi H, Maeda O, Yatabe Y, Okamoto W, Ono S, Kajiyama H, Nagashima F, Hatanaka Y, Miyachi M, Kodera Y, Yoshino T, Taniguchi H. Naito Y, et al. Among authors: hirasawa a. Int J Clin Oncol. 2020 Mar;25(3):403-417. doi: 10.1007/s10147-019-01610-y. Epub 2020 Jan 24. Int J Clin Oncol. 2020. PMID: 31974683 Free PMC article.

28

Patient-derived ovarian cancer organoids capture the genomic profiles of primary tumours applicable for drug sensitivity and resistance testing.

Nanki Y, Chiyoda T, Hirasawa A, Ookubo A, Itoh M, Ueno M, Akahane T, Kameyama K, Yamagami W, Kataoka F, Aoki D. Nanki Y, et al. Among authors: hirasawa a. Sci Rep. 2020 Jul 28;10(1):12581. doi: 10.1038/s41598-020-69488-9. Sci Rep. 2020. PMID: 32724113 Free PMC article.

29

Incidence of germline variants in Lynch syndrome-related genes among Japanese endometrial cancer patients aged 40 years or younger.

Makabe T, Yamagami W, Hirasawa A, Miyabe I, Wakatsuki T, Kikuchi M, Takahashi A, Noda J, Yamamoto G, Aoki D, Akagi K. Makabe T, et al. Among authors: hirasawa a. Int J Clin Oncol. 2021 Sep;26(9):1767-1774. doi: 10.1007/s10147-021-01953-5. Epub 2021 Jun 11. Int J Clin Oncol. 2021. PMID: 34115236

30

Current status and issues related to secondary findings in the first public insurance covered tumor genomic profiling in Japan: multi-site questionnaire survey.

Minamoto A, Yamada T, Shimada S, Kinoshita I, Aoki Y, Oda K, Ueki A, Higashigawa S, Morikawa M, Sato Y, Hirasawa A, Ogawa M, Kondo T, Yoshioka M, Kanai M, Muto M, Kosugi S. Minamoto A, et al. Among authors: hirasawa a. J Hum Genet. 2022 Oct;67(10):557-563. doi: 10.1038/s10038-022-01028-x. Epub 2022 Mar 23. J Hum Genet. 2022. PMID: 35322199

31

Epigenetic DNA hypermethylation: clinical applications in endometrial cancer (Review).

Muraki Y, Banno K, Yanokura M, Kobayashi Y, Kawaguchi M, Nomura H, Hirasawa A, Susumu N, Aoki D. Muraki Y, et al. Among authors: hirasawa a. Oncol Rep. 2009 Nov;22(5):967-72. doi: 10.3892/or_00000523. Oncol Rep. 2009. PMID: 19787208 Review.

32

FFA1-selective agonistic activity based on docking simulation using FFA1 and GPR120 homology models.

Takeuchi M, Hirasawa A, Hara T, Kimura I, Hirano T, Suzuki T, Miyata N, Awaji T, Ishiguro M, Tsujimoto G. Takeuchi M, et al. Among authors: hirasawa a. Br J Pharmacol. 2013 Apr;168(7):1570-83. doi: 10.1111/j.1476-5381.2012.02052.x. Br J Pharmacol. 2013. PMID: 22639973 Free PMC article.

33

Prevalence of disease-causing genes in Japanese patients with BRCA1/2-wildtype hereditary breast and ovarian cancer syndrome.

Kaneyasu T, Mori S, Yamauchi H, Ohsumi S, Ohno S, Aoki D, Baba S, Kawano J, Miki Y, Matsumoto N, Nagasaki M, Yoshida R, Akashi-Tanaka S, Iwase T, Kitagawa D, Masuda K, Hirasawa A, Arai M, Takei J, Ide Y, Gotoh O, Yaguchi N, Nishi M, Kaneko K, Matsuyama Y, Okawa M, Suzuki M, Nezu A, Yokoyama S, Amino S, Inuzuka M, Noda T, Nakamura S. Kaneyasu T, et al. Among authors: hirasawa a. NPJ Breast Cancer. 2020 Jun 12;6:25. doi: 10.1038/s41523-020-0163-1. eCollection 2020. NPJ Breast Cancer. 2020. PMID: 32566746 Free PMC article.

34

Retroperitoneal leiomyosarcoma in a female patient with a germline splicing variant RAD51D c.904-2A > T: a case report.

Futagawa M, Yamamoto H, Kochi M, Urakawa Y, Sogawa R, Kato F, Okazawa-Sakai M, Ennishi D, Shinozaki K, Inoue H, Yanai H, Hirasawa A. Futagawa M, et al. Among authors: hirasawa a. Hered Cancer Clin Pract. 2021 Nov 27;19(1):48. doi: 10.1186/s13053-021-00205-x. Hered Cancer Clin Pract. 2021. PMID: 34838098 Free PMC article.

35

Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis.

Ichimura A, Hirasawa A, Hara T, Tsujimoto G. Ichimura A, et al. Among authors: hirasawa a. Prostaglandins Other Lipid Mediat. 2009 Sep;89(3-4):82-8. doi: 10.1016/j.prostaglandins.2009.05.003. Epub 2009 May 19. Prostaglandins Other Lipid Mediat. 2009. PMID: 19460454 Review.

36

Role of free fatty acid receptors in the regulation of energy metabolism.

Hara T, Kashihara D, Ichimura A, Kimura I, Tsujimoto G, Hirasawa A. Hara T, et al. Among authors: hirasawa a. Biochim Biophys Acta. 2014 Sep;1841(9):1292-300. doi: 10.1016/j.bbalip.2014.06.002. Epub 2014 Jun 10. Biochim Biophys Acta. 2014. PMID: 24923869 Review.

37

Risk-reducing surgery in hereditary gynecological cancer: Clinical applications in Lynch syndrome and hereditary breast and ovarian cancer.

Adachi M, Banno K, Yanokura M, Iida M, Nakamura K, Nogami Y, Umene K, Masuda K, Kisu I, Ueki A, Hirasawa A, Tominaga E, Aoki D. Adachi M, et al. Among authors: hirasawa a. Mol Clin Oncol. 2015 Mar;3(2):267-273. doi: 10.3892/mco.2014.460. Epub 2014 Nov 20. Mol Clin Oncol. 2015. PMID: 25798252 Free PMC article.

38

The Effects of a Selective CK2 Inhibitor on Anti-glomerular Basement Membrane Glomerulonephritis in Rats.

Shi J, Liu N, Xiao Y, Takei Y, Yasue M, Suzuki Y, Hou Z, Ohno H, Yamada M, Fuchi N, Oshida K, Miyamoto Y, Tsujimoto G, Hirasawa A. Shi J, et al. Among authors: hirasawa a. Biol Pharm Bull. 2015;38(9):1345-51. doi: 10.1248/bpb.b15-00195. Biol Pharm Bull. 2015. PMID: 26328489 Free article.

39

Prospective feasibility study of neoadjuvant dose-dense paclitaxel plus carboplatin with bevacizumab therapy followed by interval debulking surgery for advanced ovarian, fallopian tube, and primary peritoneal cancer patients.

Iwasa-Inoue N, Nomura H, Kataoka F, Chiyoda T, Yoshihama T, Nanki Y, Sakai K, Kobayashi Y, Yamagami W, Morisada T, Hirasawa A, Aoki D. Iwasa-Inoue N, et al. Among authors: hirasawa a. Int J Clin Oncol. 2022 Feb;27(2):441-447. doi: 10.1007/s10147-021-02050-3. Epub 2021 Oct 14. Int J Clin Oncol. 2022. PMID: 34648082

40

TP53 variants in p53 signatures and the clonality of STICs in RRSO samples.

Akahane T, Masuda K, Hirasawa A, Kobayashi Y, Ueki A, Kawaida M, Misu K, Nakamura K, Nagai S, Chiyoda T, Yamagami W, Hayashi S, Kataoka F, Banno K, Sugano K, Okita H, Kosaki K, Nishihara H, Aoki D. Akahane T, et al. Among authors: hirasawa a. J Gynecol Oncol. 2022 Jul;33(4):e50. doi: 10.3802/jgo.2022.33.e50. Epub 2022 Mar 21. J Gynecol Oncol. 2022. PMID: 35557033 Free PMC article.

41

[Panel Discussion - Problems in the Cancer Genomic Medicine].

Ishioka C, Muto M, Yachida S, Shirota H, Hirasawa A, Miyagawa K, Ashizawa K, Kinoshita I, Nishihara H, Matsuura N, Sakurai A. Ishioka C, et al. Among authors: hirasawa a. Gan To Kagaku Ryoho. 2022 Sep;49(9):1014-1017. Gan To Kagaku Ryoho. 2022. PMID: 36156030 Japanese.

42

Association of 17q21-q24 gain in ovarian clear cell adenocarcinomas with poor prognosis and identification of PPM1D and APPBP2 as likely amplification targets.

Hirasawa A, Saito-Ohara F, Inoue J, Aoki D, Susumu N, Yokoyama T, Nozawa S, Inazawa J, Imoto I. Hirasawa A, et al. Clin Cancer Res. 2003 Jun;9(6):1995-2004. Clin Cancer Res. 2003. PMID: 12796361

43

Identification of germline MSH2 gene mutations in endometrial cancer not fulfilling the new clinical criteria for hereditary nonpolyposis colorectal cancer.

Banno K, Susumu N, Hirao T, Yanokura M, Hirasawa A, Aoki D, Udagawa Y, Sugano K, Nozawa S. Banno K, et al. Among authors: hirasawa a. Cancer Genet Cytogenet. 2003 Oct 1;146(1):58-65. doi: 10.1016/s0165-4608(03)00157-2. Cancer Genet Cytogenet. 2003. PMID: 14499697

44

Unfavorable prognostic factors associated with high frequency of microsatellite instability and comparative genomic hybridization analysis in endometrial cancer.

Hirasawa A, Aoki D, Inoue J, Imoto I, Susumu N, Sugano K, Nozawa S, Inazawa J. Hirasawa A, et al. Clin Cancer Res. 2003 Nov 15;9(15):5675-82. Clin Cancer Res. 2003. PMID: 14654551

45

Two Japanese kindreds occurring endometrial cancer meeting new clinical criteria for hereditary non-polyposis colorectal cancer (HNPCC), Amsterdam Criteria II.

Banno K, Susumu N, Hirao T, Yanokura M, Hirasawa A, Aoki D, Udagawa Y, Sugano K, Nozawa S. Banno K, et al. Among authors: hirasawa a. J Obstet Gynaecol Res. 2004 Aug;30(4):287-92. doi: 10.1111/j.1447-0756.2004.00195.x. J Obstet Gynaecol Res. 2004. PMID: 15238104

46

[Outline of treatment for endometrial cancer].

Aoki D, Hirasawa A, Susumu N, Nozawa S. Aoki D, et al. Among authors: hirasawa a. Nihon Rinsho. 2004 Oct;62 Suppl 10:324-8. Nihon Rinsho. 2004. PMID: 15535260 Review. Japanese. No abstract available.

47

[Diagnostic significance of tumor markers for gynecologic malignancies].

Aoki D, Hirasawa A, Susumu N. Aoki D, et al. Among authors: hirasawa a. Gan To Kagaku Ryoho. 2005 Mar;32(3):411-6. Gan To Kagaku Ryoho. 2005. PMID: 15791829 Review. Japanese.

48

Clinicopathologic manifestations of early-onset endometrial cancer in Japanese women with a familial predisposition to cancer.

Yamagami W, Susumu N, Banno K, Hirao T, Kataoka F, Hirasawa A, Suzuki N, Aoki D, Nozawa S. Yamagami W, et al. Among authors: hirasawa a. J Obstet Gynaecol Res. 2005 Oct;31(5):444-51. doi: 10.1111/j.1447-0756.2005.00318.x. J Obstet Gynaecol Res. 2005. PMID: 16176516

49

Relationship of the aberrant DNA hypermethylation of cancer-related genes with carcinogenesis of endometrial cancer.

Banno K, Yanokura M, Susumu N, Kawaguchi M, Hirao N, Hirasawa A, Tsukazaki K, Aoki D. Banno K, et al. Among authors: hirasawa a. Oncol Rep. 2006 Dec;16(6):1189-96. Oncol Rep. 2006. PMID: 17089036

50

Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer.

Yanokura M, Banno K, Kawaguchi M, Hirao N, Hirasawa A, Susumu N, Tsukazaki K, Aoki D. Yanokura M, et al. Among authors: hirasawa a. Oncol Rep. 2007 Jan;17(1):41-8. Oncol Rep. 2007. PMID: 17143476

51

Epigenetic inactivation of the CHFR gene in cervical cancer contributes to sensitivity to taxanes.

Banno K, Yanokura M, Kawaguchi M, Kuwabara Y, Akiyoshi J, Kobayashi Y, Iwata T, Hirasawa A, Fujii T, Susumu N, Tsukazaki K, Aoki D. Banno K, et al. Among authors: hirasawa a. Int J Oncol. 2007 Oct;31(4):713-20. Int J Oncol. 2007. PMID: 17786301

52

Can ABCF2 protein expression predict the prognosis of uterine cancer?

Nishimura S, Tsuda H, Miyagi Y, Hirasawa A, Suzuki A, Kataoka F, Nomura H, Chiyoda T, Banno K, Fujii T, Susumu N, Aoki D. Nishimura S, et al. Among authors: hirasawa a. Br J Cancer. 2008 Nov 18;99(10):1651-5. doi: 10.1038/sj.bjc.6604734. Br J Cancer. 2008. PMID: 19002184 Free PMC article.

53

Cross-sectional analysis of germline BRCA1 and BRCA2 mutations in Japanese patients suspected to have hereditary breast/ovarian cancer.

Sugano K, Nakamura S, Ando J, Takayama S, Kamata H, Sekiguchi I, Ubukata M, Kodama T, Arai M, Kasumi F, Hirai Y, Ikeda T, Jinno H, Kitajima M, Aoki D, Hirasawa A, Takeda Y, Yazaki K, Fukutomi T, Kinoshita T, Tsunematsu R, Yoshida T, Izumi M, Umezawa S, Yagata H, Komatsu H, Arimori N, Matoba N, Gondo N, Yokoyama S, Miki Y. Sugano K, et al. Among authors: hirasawa a. Cancer Sci. 2008 Oct;99(10):1967-76. doi: 10.1111/j.1349-7006.2008.00944.x. Cancer Sci. 2008. PMID: 19016756 Free PMC article.

54

Analysis of a correlation between the BRAF V600E mutation and abnormal DNA mismatch repair in patients with sporadic endometrial cancer.

Kawaguchi M, Yanokura M, Banno K, Kobayashi Y, Kuwabara Y, Kobayashi M, Nomura H, Hirasawa A, Susumu N, Aoki D. Kawaguchi M, et al. Among authors: hirasawa a. Int J Oncol. 2009 Jun;34(6):1541-7. doi: 10.3892/ijo_00000283. Int J Oncol. 2009. PMID: 19424571

55

Analysis of candidate target genes for mononucleotide repeat mutation in microsatellite instability-high (MSI-H) endometrial cancer.

Kawaguchi M, Banno K, Yanokura M, Kobayashi Y, Kishimi A, Ogawa S, Kisu I, Nomura H, Hirasawa A, Susumu N, Aoki D. Kawaguchi M, et al. Among authors: hirasawa a. Int J Oncol. 2009 Nov;35(5):977-82. doi: 10.3892/ijo_00000411. Int J Oncol. 2009. PMID: 19787250

56

Endometrial cancer as a familial tumor: pathology and molecular carcinogenesis (review).

Banno K, Yanokura M, Kobayashi Y, Kawaguchi M, Nomura H, Hirasawa A, Susumu N, Aoki D. Banno K, et al. Among authors: hirasawa a. Curr Genomics. 2009 Apr;10(2):127-32. doi: 10.2174/138920209787847069. Curr Genomics. 2009. PMID: 19794885 Free PMC article.

57

Amplification of GNAS may be an independent, qualitative, and reproducible biomarker to predict progression-free survival in epithelial ovarian cancer.

Tominaga E, Tsuda H, Arao T, Nishimura S, Takano M, Kataoka F, Nomura H, Hirasawa A, Aoki D, Nishio K. Tominaga E, et al. Among authors: hirasawa a. Gynecol Oncol. 2010 Aug 1;118(2):160-6. doi: 10.1016/j.ygyno.2010.03.010. Epub 2010 May 26. Gynecol Oncol. 2010. PMID: 20537689

58

A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.

Uno S, Zembutsu H, Hirasawa A, Takahashi A, Kubo M, Akahane T, Aoki D, Kamatani N, Hirata K, Nakamura Y. Uno S, et al. Among authors: hirasawa a. Nat Genet. 2010 Aug;42(8):707-10. doi: 10.1038/ng.612. Epub 2010 Jul 4. Nat Genet. 2010. PMID: 20601957

59

Flexible hysteroscopy with narrow band imaging (NBI) for endoscopic diagnosis of malignant endometrial lesions.

Kisu I, Banno K, Kobayashi Y, Ono A, Masuda K, Ueki A, Nomura H, Hirasawa A, Abe T, Kouyama K, Susumu N, Aoki D. Kisu I, et al. Among authors: hirasawa a. Int J Oncol. 2011 Mar;38(3):613-8. doi: 10.3892/ijo.2011.903. Epub 2011 Jan 14. Int J Oncol. 2011. PMID: 21240458 Clinical Trial.

60

Narrow band imaging hysteroscopy: a comparative study using randomized video images.

Kisu I, Banno K, Kobayashi Y, Ono A, Masuda K, Ueki A, Nomura H, Hirasawa A, Abe T, Kouyama K, Susumu N, Aoki D. Kisu I, et al. Among authors: hirasawa a. Int J Oncol. 2011 Nov;39(5):1057-62. doi: 10.3892/ijo.2011.1131. Epub 2011 Jul 18. Int J Oncol. 2011. PMID: 21769430

61

miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer.

Tsuruta T, Kozaki K, Uesugi A, Furuta M, Hirasawa A, Imoto I, Susumu N, Aoki D, Inazawa J. Tsuruta T, et al. Among authors: hirasawa a. Cancer Res. 2011 Oct 15;71(20):6450-62. doi: 10.1158/0008-5472.CAN-11-0364. Epub 2011 Aug 25. Cancer Res. 2011. PMID: 21868754

62

Carcinoma of the Lower Uterine Segment (LUS): Clinicopathological Characteristics and Association with Lynch Syndrome.

Masuda K, Banno K, Yanokura M, Kobayashi Y, Kisu I, Ueki A, Ono A, Nomura H, Hirasawa A, Susumu N, Aoki D. Masuda K, et al. Among authors: hirasawa a. Curr Genomics. 2011 Mar;12(1):25-9. doi: 10.2174/138920211794520169. Curr Genomics. 2011. PMID: 21886452 Free PMC article.

63

Immunofluorescence-detected infiltration of CD4+FOXP3+ regulatory T cells is relevant to the prognosis of patients with endometrial cancer.

Yamagami W, Susumu N, Tanaka H, Hirasawa A, Banno K, Suzuki N, Tsuda H, Tsukazaki K, Aoki D. Yamagami W, et al. Among authors: hirasawa a. Int J Gynecol Cancer. 2011 Dec;21(9):1628-34. doi: 10.1097/IGC.0b013e31822c271f. Int J Gynecol Cancer. 2011. PMID: 21897268 Free article.

64

EGRI and FOSB gene expressions in cancer stroma are independent prognostic indicators for epithelial ovarian cancer receiving standard therapy.

Kataoka F, Tsuda H, Arao T, Nishimura S, Tanaka H, Nomura H, Chiyoda T, Hirasawa A, Akahane T, Nishio H, Nishio K, Aoki D. Kataoka F, et al. Among authors: hirasawa a. Genes Chromosomes Cancer. 2012 Mar;51(3):300-12. doi: 10.1002/gcc.21916. Epub 2011 Nov 17. Genes Chromosomes Cancer. 2012. PMID: 22095904

65

MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review).

Yanokura M, Banno K, Kobayashi Y, Kisu I, Ueki A, Ono A, Masuda K, Nomura H, Hirasawa A, Susumu N, Aoki D. Yanokura M, et al. Among authors: hirasawa a. Oncol Lett. 2010 Nov;1(6):935-940. doi: 10.3892/ol.2010.173. Epub 2010 Sep 22. Oncol Lett. 2010. PMID: 22870090 Free PMC article.

66

Relationship of lower uterine segment cancer with Lynch syndrome: a novel case with an hMLH1 germline mutation.

Masuda K, Banno K, Hirasawa A, Yanokura M, Tsuji K, Kobayashi Y, Kisu I, Ueki A, Nomura H, Tominaga E, Susumu N, Aoki D. Masuda K, et al. Among authors: hirasawa a. Oncol Rep. 2012 Nov;28(5):1537-43. doi: 10.3892/or.2012.2008. Epub 2012 Aug 31. Oncol Rep. 2012. PMID: 22940821 Free PMC article.

67

Lobular endocervical glandular hyperplasia and peritoneal pigmentation associated with Peutz-Jeghers syndrome due to a germline mutation of STK11.

Hirasawa A, Akahane T, Tsuruta T, Kobayashi Y, Masuda K, Banno K, Fujii T, Susumu N, Itsubo T, Kameyama K, Sugano K, Aoki D. Hirasawa A, et al. Ann Oncol. 2012 Nov;23(11):2990-2992. doi: 10.1093/annonc/mds492. Epub 2012 Oct 4. Ann Oncol. 2012. PMID: 23038761 Free article. No abstract available.

68

[Hereditary endometrial cancer and genetic testing].

Hirasawa A, Tsuruta T, Banno K, Susumu N, Aoki D. Hirasawa A, et al. Nihon Rinsho. 2012 Jun;70 Suppl 4:292-6. Nihon Rinsho. 2012. PMID: 23156259 Japanese. No abstract available.

69

The origin of stroma surrounding epithelial ovarian cancer cells.

Akahane T, Hirasawa A, Tsuda H, Kataoka F, Nishimura S, Tanaka H, Tominaga E, Nomura H, Chiyoda T, Iguchi Y, Yamagami W, Susumu N, Aoki D. Akahane T, et al. Among authors: hirasawa a. Int J Gynecol Pathol. 2013 Jan;32(1):26-30. doi: 10.1097/PGP.0b013e3182518533. Int J Gynecol Pathol. 2013. PMID: 23202778

70

Experience of risk-reducing salpingo-oophorectomy for a BRCA1 mutation carrier and establishment of a system performing a preventive surgery for hereditary breast and ovarian cancer syndrome in Japan: our challenges for the future.

Hirasawa A, Masuda K, Akahane T, Tsuruta T, Banno K, Makita K, Susumu N, Jinno H, Kitagawa Y, Sugano K, Kosaki K, Aoki D. Hirasawa A, et al. Jpn J Clin Oncol. 2013 May;43(5):515-9. doi: 10.1093/jjco/hyt036. Epub 2013 Mar 13. Jpn J Clin Oncol. 2013. PMID: 23487443

71

Distinguishing between lymphangioleiomyomatosis and carcinomatous peritonitis in a patient with ovarian cancer.

Hirasawa A, Sato T, Ueno M, Akahane T, Susumu N, Betsuyaku T, Aoki D. Hirasawa A, et al. J Clin Oncol. 2013 Oct 1;31(28):e427-9. doi: 10.1200/JCO.2012.45.3019. Epub 2013 Jun 10. J Clin Oncol. 2013. PMID: 23752115 No abstract available.

72

Hypertriglyceridemia is frequent in endometrial cancer survivors.

Hirasawa A, Makita K, Akahane T, Yokota M, Yamagami W, Banno K, Susumu N, Aoki D. Hirasawa A, et al. Jpn J Clin Oncol. 2013 Nov;43(11):1087-92. doi: 10.1093/jjco/hyt125. Epub 2013 Sep 1. Jpn J Clin Oncol. 2013. PMID: 23999769 Free PMC article.

73

Polymorphisms in the UGT1A1 gene predict adverse effects of irinotecan in the treatment of gynecologic cancer in Japanese patients.

Hirasawa A, Zama T, Akahane T, Nomura H, Kataoka F, Saito K, Okubo K, Tominaga E, Makita K, Susumu N, Kosaki K, Tanigawara Y, Aoki D. Hirasawa A, et al. J Hum Genet. 2013 Dec;58(12):794-8. doi: 10.1038/jhg.2013.105. Epub 2013 Oct 3. J Hum Genet. 2013. PMID: 24088669

74

Hereditary gynecological tumors associated with Peutz-Jeghers syndrome (Review).

Banno K, Kisu I, Yanokura M, Masuda K, Ueki A, Kobayashi Y, Hirasawa A, Aoki D. Banno K, et al. Among authors: hirasawa a. Oncol Lett. 2013 Nov;6(5):1184-1188. doi: 10.3892/ol.2013.1527. Epub 2013 Aug 16. Oncol Lett. 2013. PMID: 24179492 Free PMC article.

75

Family history and BRCA1/BRCA2 status among Japanese ovarian cancer patients and occult cancer in a BRCA1 mutant case.

Hirasawa A, Masuda K, Akahane T, Ueki A, Yokota M, Tsuruta T, Nomura H, Kataoka F, Tominaga E, Banno K, Makita K, Susumu N, Sugano K, Kosaki K, Kameyama K, Aoki D. Hirasawa A, et al. Jpn J Clin Oncol. 2014 Jan;44(1):49-56. doi: 10.1093/jjco/hyt171. Epub 2013 Nov 11. Jpn J Clin Oncol. 2014. PMID: 24218521

76

A tumor of the uterine cervix with a complex histology in a Peutz-Jeghers syndrome patient with genomic deletion of the STK11 exon 1 region.

Kobayashi Y, Masuda K, Kimura T, Nomura H, Hirasawa A, Banno K, Susumu N, Sugano K, Aoki D. Kobayashi Y, et al. Among authors: hirasawa a. Future Oncol. 2014 Feb;10(2):171-7. doi: 10.2217/fon.13.180. Future Oncol. 2014. PMID: 24490603

77

Clinicopathological study on para-aortic lymph node metastasis without pelvic lymph node metastasis in endometrial cancer.

Tomisato S, Yamagami W, Susumu N, Kuwahata M, Takigawa A, Nomura H, Kataoka F, Hirasawa A, Banno K, Aoki D. Tomisato S, et al. Among authors: hirasawa a. J Obstet Gynaecol Res. 2014 Jun;40(6):1733-9. doi: 10.1111/jog.12399. J Obstet Gynaecol Res. 2014. PMID: 24888941

78

Features of ovarian cancer in Lynch syndrome (Review).

Nakamura K, Banno K, Yanokura M, Iida M, Adachi M, Masuda K, Ueki A, Kobayashi Y, Nomura H, Hirasawa A, Tominaga E, Aoki D. Nakamura K, et al. Among authors: hirasawa a. Mol Clin Oncol. 2014 Nov;2(6):909-916. doi: 10.3892/mco.2014.397. Epub 2014 Aug 20. Mol Clin Oncol. 2014. PMID: 25279173 Free PMC article.

79

Osteoporosis is less frequent in endometrial cancer survivors with hypertriglyceridemia.

Hirasawa A, Makita K, Akahane T, Yamagami W, Makabe T, Yokota M, Horiba Y, Ogawa M, Yanamoto S, Deshimaru R, Tominaga E, Banno K, Susumu N, Aoki D. Hirasawa A, et al. Jpn J Clin Oncol. 2015 Jan;45(1):127-31. doi: 10.1093/jjco/hyu164. Epub 2014 Oct 16. Jpn J Clin Oncol. 2015. PMID: 25324478

80

Clinicopathologic analysis with immunohistochemistry for DNA mismatch repair protein expression in synchronous primary endometrial and ovarian cancers.

Kobayashi Y, Nakamura K, Nomura H, Banno K, Irie H, Adachi M, Iida M, Umene K, Nogami Y, Masuda K, Kisu I, Ueki A, Yamagami W, Kataoka F, Hirasawa A, Tominaga E, Susumu N, Aoki D. Kobayashi Y, et al. Among authors: hirasawa a. Int J Gynecol Cancer. 2015 Mar;25(3):440-6. doi: 10.1097/IGC.0000000000000377. Int J Gynecol Cancer. 2015. PMID: 25695547 Free article.

81

High Expression of SQSTM1/p62 Protein Is Associated with Poor Prognosis in Epithelial Ovarian Cancer.

Iwadate R, Inoue J, Tsuda H, Takano M, Furuya K, Hirasawa A, Aoki D, Inazawa J. Iwadate R, et al. Among authors: hirasawa a. Acta Histochem Cytochem. 2014;47(6):295-301. doi: 10.1267/ahc.14048. Epub 2014 Dec 20. Acta Histochem Cytochem. 2014. PMID: 25859063 Free PMC article.

82

Intratumoral CD8+ Lymphocyte Infiltration as a Prognostic Factor and Its Relationship With Cyclooxygenase 2 Expression and Microsatellite Instability in Endometrial Cancer.

Suemori T, Susumu N, Iwata T, Banno K, Yamagami W, Hirasawa A, Sugano K, Matsumoto E, Aoki D. Suemori T, et al. Among authors: hirasawa a. Int J Gynecol Cancer. 2015 Sep;25(7):1165-72. doi: 10.1097/IGC.0000000000000482. Int J Gynecol Cancer. 2015. PMID: 26111272 Free article.

83

High Expression of p62 Protein Is Associated with Poor Prognosis and Aggressive Phenotypes in Endometrial Cancer.

Iwadate R, Inoue J, Tsuda H, Takano M, Furuya K, Hirasawa A, Aoki D, Inazawa J. Iwadate R, et al. Among authors: hirasawa a. Am J Pathol. 2015 Sep;185(9):2523-33. doi: 10.1016/j.ajpath.2015.05.008. Epub 2015 Jul 7. Am J Pathol. 2015. PMID: 26162509 Free article.

84

Polymorphisms of estrogen metabolism-related genes ESR1, UGT2B17, and UGT1A1 are not associated with osteoporosis in surgically menopausal Japanese women.

Yokota M, Hirasawa A, Makita K, Akahane T, Sakai K, Makabe T, Horiba Y, Yamagami W, Ogawa M, Iwata T, Yanamoto S, Deshimaru R, Banno K, Susumu N, Aoki D. Yokota M, et al. Among authors: hirasawa a. Prz Menopauzalny. 2015 Sep;14(3):161-7. doi: 10.5114/pm.2015.54339. Epub 2015 Sep 30. Prz Menopauzalny. 2015. PMID: 26528103 Free PMC article.

85

Factors affecting pregnancy outcomes in young women treated with fertility-preserving therapy for well-differentiated endometrial cancer or atypical endometrial hyperplasia.

Inoue O, Hamatani T, Susumu N, Yamagami W, Ogawa S, Takemoto T, Hirasawa A, Banno K, Kuji N, Tanaka M, Aoki D. Inoue O, et al. Among authors: hirasawa a. Reprod Biol Endocrinol. 2016 Jan 15;14:2. doi: 10.1186/s12958-015-0136-7. Reprod Biol Endocrinol. 2016. PMID: 26769300 Free PMC article.

86

Retrospective Analysis on the Feasibility and Efficacy of Docetaxel-Cisplatin Therapy for Recurrent Endometrial Cancer.

Ninomiya T, Yamagami W, Susumu N, Makabe T, Sakai K, Wada M, Takigawa A, Chiyoda T, Nomura H, Kataoka F, Hirasawa A, Banno K, Aoki D. Ninomiya T, et al. Among authors: hirasawa a. Anticancer Res. 2016 Apr;36(4):1751-8. Anticancer Res. 2016. PMID: 27069155

87

Characterization of the STK11 splicing variant as a normal splicing isomer in a patient with Peutz-Jeghers syndrome harboring genomic deletion of the STK11 gene.

Masuda K, Kobayashi Y, Kimura T, Umene K, Misu K, Nomura H, Hirasawa A, Banno K, Kosaki K, Aoki D, Sugano K. Masuda K, et al. Among authors: hirasawa a. Hum Genome Var. 2016 Mar 3;3:16002. doi: 10.1038/hgv.2016.2. eCollection 2016. Hum Genome Var. 2016. PMID: 27081568 Free PMC article.

88

Symptoms and effects of physical factors in Japanese middle-aged women.

Yokota M, Makita K, Hirasawa A, Iwata T, Aoki D. Yokota M, et al. Among authors: hirasawa a. Menopause. 2016 Sep;23(9):974-83. doi: 10.1097/GME.0000000000000660. Menopause. 2016. PMID: 27272227

89

Carcinoma of the lower uterine segment diagnosed with Lynch syndrome based on MSH6 germline mutation: A case report.

Adachi M, Banno K, Masuda K, Yanokura M, Iijima M, Takeda T, Kunitomi H, Kobayashi Y, Yamagami W, Hirasawa A, Kameyama K, Sugano K, Aoki D. Adachi M, et al. Among authors: hirasawa a. J Obstet Gynaecol Res. 2017 Feb;43(2):416-420. doi: 10.1111/jog.13202. Epub 2016 Dec 8. J Obstet Gynaecol Res. 2017. PMID: 27928858

90

UGT1A1 polymorphism as a prognostic indicator of stage I ovarian clear cell carcinoma patients treated with irinotecan.

Yoshihama T, Hirasawa A, Nomura H, Akahane T, Nanki Y, Yamagami W, Kataoka F, Tominaga E, Susumu N, Mushiroda T, Aoki D. Yoshihama T, et al. Among authors: hirasawa a. Jpn J Clin Oncol. 2017 Feb 4;47(2):170-174. doi: 10.1093/jjco/hyw163. Jpn J Clin Oncol. 2017. PMID: 28173214

91

Clinical utility of a self-administered questionnaire for assessment of hereditary gynecologic cancer.

Masuda K, Hirasawa A, Irie-Kunitomi H, Akahane T, Ueki A, Kobayashi Y, Yamagami W, Nomura H, Kataoka F, Tominaga E, Banno K, Susumu N, Aoki D. Masuda K, et al. Among authors: hirasawa a. Jpn J Clin Oncol. 2017 May 1;47(5):401-406. doi: 10.1093/jjco/hyx019. Jpn J Clin Oncol. 2017. PMID: 28334914 Free PMC article.

92

Clinical utility of a self-administered questionnaire for assessment of hereditary gynecologic cancer.

Masuda K, Hirasawa A, Irie-Kunitomi H, Akahane T, Ueki A, Kobayashi Y, Yamagami W, Nomura H, Kataoka F, Tominaga E, Banno K, Susumu N, Aoki D. Masuda K, et al. Among authors: hirasawa a. Jpn J Clin Oncol. 2017 May 1;47(5):473. doi: 10.1093/jjco/hyx037. Jpn J Clin Oncol. 2017. PMID: 28334959 Free PMC article. No abstract available.

93

A Comparison of Dye Versus Fluorescence Methods for Sentinel Lymph Node Mapping in Endometrial Cancer.

Yamagami W, Susumu N, Kataoka F, Makabe T, Sakai K, Ninomiya T, Wada M, Nomura H, Hirasawa A, Banno K, Nakahara T, Kameyama K, Aoki D. Yamagami W, et al. Among authors: hirasawa a. Int J Gynecol Cancer. 2017 Sep;27(7):1517-1524. doi: 10.1097/IGC.0000000000000997. Int J Gynecol Cancer. 2017. PMID: 28562470 Free article.

94

Efficacy and safety of dose-dense paclitaxel plus carboplatin as neoadjuvant chemotherapy for advanced ovarian, fallopian tube or peritoneal cancer.

Yoshihama T, Nomura H, Iwasa N, Kataoka F, Hashimoto S, Nanki Y, Hirano T, Makabe T, Sakai K, Yamagami W, Hirasawa A, Aoki D. Yoshihama T, et al. Among authors: hirasawa a. Jpn J Clin Oncol. 2017 Nov 1;47(11):1019-1023. doi: 10.1093/jjco/hyx118. Jpn J Clin Oncol. 2017. PMID: 28973541

95

ADAM9 is over-expressed in human ovarian clear cell carcinomas and suppresses cisplatin-induced cell death.

Ueno M, Shiomi T, Mochizuki S, Chijiiwa M, Shimoda M, Kanai Y, Kataoka F, Hirasawa A, Susumu N, Aoki D, Okada Y. Ueno M, et al. Among authors: hirasawa a. Cancer Sci. 2018 Feb;109(2):471-482. doi: 10.1111/cas.13469. Cancer Sci. 2018. PMID: 29247567 Free PMC article.

96

Prevalence of pathogenic germline variants detected by multigene sequencing in unselected Japanese patients with ovarian cancer.

Hirasawa A, Imoto I, Naruto T, Akahane T, Yamagami W, Nomura H, Masuda K, Susumu N, Tsuda H, Aoki D. Hirasawa A, et al. Oncotarget. 2017 Nov 28;8(68):112258-112267. doi: 10.18632/oncotarget.22733. eCollection 2017 Dec 22. Oncotarget. 2017. PMID: 29348823 Free PMC article.

97

Is repeated high-dose medroxyprogesterone acetate (MPA) therapy permissible for patients with early stage endometrial cancer or atypical endometrial hyperplasia who desire preserving fertility?

Yamagami W, Susumu N, Makabe T, Sakai K, Nomura H, Kataoka F, Hirasawa A, Banno K, Aoki D. Yamagami W, et al. Among authors: hirasawa a. J Gynecol Oncol. 2018 Mar;29(2):e21. doi: 10.3802/jgo.2018.29.e21. Epub 2018 Jan 2. J Gynecol Oncol. 2018. PMID: 29400014 Free PMC article.

98

Blood-direct InvaderPlus^® as a new method for genetic testing.

Hirasawa A, Akahane T, Tanigawara Y, Aoki D. Hirasawa A, et al. Per Med. 2012 Aug;9(6):657-663. doi: 10.2217/pme.12.71. Per Med. 2012. PMID: 29768795

99

GSTP1 rs1695 is associated with both hematological toxicity and prognosis of ovarian cancer treated with paclitaxel plus carboplatin combination chemotherapy: a comprehensive analysis using targeted resequencing of 100 pharmacogenes.

Yoshihama T, Fukunaga K, Hirasawa A, Nomura H, Akahane T, Kataoka F, Yamagami W, Aoki D, Mushiroda T. Yoshihama T, et al. Among authors: hirasawa a. Oncotarget. 2018 Jul 3;9(51):29789-29800. doi: 10.18632/oncotarget.25712. eCollection 2018 Jul 3. Oncotarget. 2018. PMID: 30038720 Free PMC article.

100

Synchronous endometrial and ovarian cancer in Lynch syndrome with a MSH2 germline mutation: A case report.

Takeda T, Banno K, Yanokura M, Anko M, Kobayashi A, Sera A, Takahashi T, Adachi M, Kobayashi Y, Hayashi S, Nomura H, Hirasawa A, Tominaga E, Aoki D. Takeda T, et al. Among authors: hirasawa a. Mol Clin Oncol. 2018 Nov;9(5):479-484. doi: 10.3892/mco.2018.1723. Epub 2018 Sep 17. Mol Clin Oncol. 2018. PMID: 30402230 Free PMC article.

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