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Design of protein-binding proteins from the target structure alone.
Cao L, Coventry B, Goreshnik I, Huang B, Sheffler W, Park JS, Jude KM, Marković I, Kadam RU, Verschueren KHG, Verstraete K, Walsh STR, Bennett N, Phal A, Yang A, Kozodoy L, DeWitt M, Picton L, Miller L, Strauch EM, DeBouver ND, Pires A, Bera AK, Halabiya S, Hammerson B, Yang W, Bernard S, Stewart L, Wilson IA, Ruohola-Baker H, Schlessinger J, Lee S, Savvides SN, Garcia KC, Baker D. Cao L, et al. Among authors: lee s. Nature. 2022 May;605(7910):551-560. doi: 10.1038/s41586-022-04654-9. Epub 2022 Mar 24. Nature. 2022. PMID: 35332283 Free PMC article.
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.
Edman NI, Redler RL, Phal A, Schlichthaerle T, Srivatsan SR, Etemadi A, An SJ, Favor A, Ehnes D, Li Z, Praetorius F, Gordon M, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D. Edman NI, et al. Among authors: lee s. bioRxiv [Preprint]. 2023 Mar 15:2023.03.14.532666. doi: 10.1101/2023.03.14.532666. bioRxiv. 2023. Update in: Cell. 2024 Jul 11;187(14):3726-3740.e43. doi: 10.1016/j.cell.2024.05.025. PMID: 36993355 Free PMC article. Updated. Preprint.
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.
Edman NI, Phal A, Redler RL, Schlichthaerle T, Srivatsan SR, Ehnes DD, Etemadi A, An SJ, Favor A, Li Z, Praetorius F, Gordon M, Vincent T, Marchiano S, Blakely L, Lin C, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Zheng Y, Murry CE, Schweppe DK, Freedman BS, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D. Edman NI, et al. Among authors: lee s. Cell. 2024 Jul 11;187(14):3726-3740.e43. doi: 10.1016/j.cell.2024.05.025. Epub 2024 Jun 10. Cell. 2024. PMID: 38861993 Free article.
CT-P17 Adalimumab Biosimilar in Patients with Moderate-to-Severe Chronic Plaque Psoriasis: An Open-Label Extension of a Phase 3 Interchangeability Study.
Pariser DM, Lebwohl MG, Jaworski J, Trefler J, Daniluk S, Dudek A, Baran W, Owczarek W, Brzewski P, Sikora M, Krogulec M, Kim S, Suh J, Choi E, Cha J, Lee H, Lee S, Koo JY. Pariser DM, et al. Among authors: lee h, lee s. Dermatol Ther (Heidelb). 2025 Mar 27. doi: 10.1007/s13555-025-01383-5. Online ahead of print. Dermatol Ther (Heidelb). 2025. PMID: 40148673
DYRK1A inhibition results in MYC and ERK activation rendering KMT2A-R acute lymphoblastic leukemia cells sensitive to BCL2 inhibition.
Ayyadevara VSSA, Wertheim G, Gaur S, Chukinas JA, Loftus JP, Lee SJ, Kumar A, Swaminathan S, Bhansali RS, Childers W, Geng H, Milne TA, Hua X, Bernt KM, Besson T, Shi J, Crispino JD, Carroll M, Tasian SK, Hurtz C. Ayyadevara VSSA, et al. Among authors: lee sj. Leukemia. 2025 Mar 27. doi: 10.1038/s41375-025-02575-w. Online ahead of print. Leukemia. 2025. PMID: 40148558
ICU Admission Prediction for Patients With Kawasaki Disease or MIS-C Using Machine Learning.
Woo J, Mosier R, Mukherjee R, Harahsheh AS, Jain SS, Raghuveer G, Sundaram B, Lee S, Portman MA, Dahdah N, Fabi M, Nowlen TT, Dionne A, El Ganzoury M, Harris TH, Barnes BT, Dallaire F, Dancey P, Norozi K, Alsalehi M, Selamet Tierney ES, Szmuszkovicz JR, Jone PN, Prasad D, Yetman AT, Misra N, Hicar MD, Thacker D, Choueiter NF, Cooke EF, Mauriello D, Mondal T, Elias MD, McHugh KE, Merves SA, Garrido-Garcia LM, Khoury M, Larios G, Chinni B, Pruthi K, Yang W, Greenstein J, Taylor C, Farid P, McCrindle BW, Manlhiot C; International Kawasaki Disease Registry. Woo J, et al. Among authors: lee s. JACC Adv. 2025 Feb 27;4(3):101621. doi: 10.1016/j.jacadv.2025.101621. Online ahead of print. JACC Adv. 2025. PMID: 40147056
Omni-Directional Assembly of 2D Single-Crystalline Metal Nanosheets.
Kim S, Choi HK, Song YS, Seo MY, Lee H, Bae S, Moon BJ, Lee SK, Lee SH, Kim TW. Kim S, et al. Among authors: lee sh, lee h, lee sk. Adv Mater. 2025 Mar 27:e2501632. doi: 10.1002/adma.202501632. Online ahead of print. Adv Mater. 2025. PMID: 40145860
Primary polydipsia in a cat.
Kim J, Yoon S, Kim M, Lee S, Song W, Yun Y. Kim J, et al. Among authors: lee s. JFMS Open Rep. 2025 Mar 23;11(1):20551169241311680. doi: 10.1177/20551169241311680. eCollection 2025 Jan-Jun. JFMS Open Rep. 2025. PMID: 40143954 Free PMC article.
Artificial Intelligence-Enhanced Analysis of Echocardiography-Based Radiomic Features for Myocardial Hypertrophy Detection and Etiology Differentiation.
Moon I, Lee J, Lee SA, Jeong D, Jeon J, Jang Y, Jeong S, Kim J, Choi HM, Hwang IC, Hong Y, Cho GY, Yoon YE, Chang HJ. Moon I, et al. Among authors: lee j, lee sa. Circ Cardiovasc Imaging. 2025 Mar 27:e017436. doi: 10.1161/CIRCIMAGING.124.017436. Online ahead of print. Circ Cardiovasc Imaging. 2025. PMID: 40143828
White Matter Microstructural Alterations in Type 2 Diabetes: A Combined UK Biobank Study of Diffusion Tensor Imaging and Neurite Orientation Dispersion and Density Imaging.
Alotaibi A, Alqarras M, Podlasek A, Almanaa A, AlTokhis A, Aldhebaib A, Aldebasi B, Almutairi M, Tench CR, Almanaa M, Mohammadi-Nejad AR, Constantinescu CS, Dineen RA, Lee S. Alotaibi A, et al. Among authors: lee s. Medicina (Kaunas). 2025 Mar 6;61(3):455. doi: 10.3390/medicina61030455. Medicina (Kaunas). 2025. PMID: 40142266
The contribution of de novo coding mutations to meningomyelocele.
Ha YJ, Nisal A, Tang I, Lee C, Jhamb I, Wallace C, Howarth R, Schroeder S, Vong KL, Meave N, Jiwani F, Barrows C, Lee S, Jiang N, Patel A, Bagga K, Banka N, Friedman L, Blanco FA, Yu S, Rhee S, Jeong HS, Plutzer I, Major MB, Benoit B, Poüs C, Heffner C, Kibar Z, Bot GM, Northrup H, Au KS, Strain M, Ashley-Koch AE, Finnell RH, Le JT, Meltzer HS, Araujo C, Machado HR, Stevenson RE, Yurrita A, Mumtaz S, Ahmed A, Khara MH, Mutchinick OM, Medina-Bereciartu JR, Hildebrandt F, Melikishvili G, Marwan AI, Capra V, Noureldeen MM, Salem AMS, Issa MY, Zaki MS, Xu L, Lee JE, Shin D, Alkelai A, Shuldiner AR, Kingsmore SF, Murray SA, Gee HY, Miller WT, Tolias KF, Wallingford JB; Spina Bifida Sequencing Consortium; Kim S, Gleeson JG. Ha YJ, et al. Among authors: lee je, lee c, lee s. Nature. 2025 Mar 26. doi: 10.1038/s41586-025-08676-x. Online ahead of print. Nature. 2025. PMID: 40140573
Design, synthesis and evaluation of acetylcholine-antitumor lipid hybrids led to identification of a potential anticancer agent disrupting the CDK4/6-Rb pathway in lung cancer.
Hassan AHE, Bae ES, Jeong Y, Ock CW, El-Sayed SM, Kim M, Radwan MF, Ibrahim TS, Cho JY, Park BY, Sim J, Lee SK, Lee YS. Hassan AHE, et al. Among authors: lee sk, lee ys. RSC Med Chem. 2025 Mar 7. doi: 10.1039/d4md01007h. Online ahead of print. RSC Med Chem. 2025. PMID: 40135145 Free PMC article.
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