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Page 1
Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis.
Berkers G, van Mourik P, Vonk AM, Kruisselbrink E, Dekkers JF, de Winter-de Groot KM, Arets HGM, Marck-van der Wilt REP, Dijkema JS, Vanderschuren MM, Houwen RHJ, Heijerman HGM, van de Graaf EA, Elias SG, Majoor CJ, Koppelman GH, Roukema J, Bakker M, Janssens HM, van der Meer R, Vries RGJ, Clevers HC, de Jonge HR, Beekman JM, van der Ent CK. Berkers G, et al. Among authors: majoor cj. Cell Rep. 2019 Feb 12;26(7):1701-1708.e3. doi: 10.1016/j.celrep.2019.01.068. Cell Rep. 2019. PMID: 30759382 Free article.
Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.
Dekkers JF, Berkers G, Kruisselbrink E, Vonk A, de Jonge HR, Janssens HM, Bronsveld I, van de Graaf EA, Nieuwenhuis EE, Houwen RH, Vleggaar FP, Escher JC, de Rijke YB, Majoor CJ, Heijerman HG, de Winter-de Groot KM, Clevers H, van der Ent CK, Beekman JM. Dekkers JF, et al. Among authors: majoor cj. Sci Transl Med. 2016 Jun 22;8(344):344ra84. doi: 10.1126/scitranslmed.aad8278. Sci Transl Med. 2016. PMID: 27334259
β2-Adrenergic receptor agonists activate CFTR in intestinal organoids and subjects with cystic fibrosis.
Vijftigschild LA, Berkers G, Dekkers JF, Zomer-van Ommen DD, Matthes E, Kruisselbrink E, Vonk A, Hensen CE, Heida-Michel S, Geerdink M, Janssens HM, van de Graaf EA, Bronsveld I, de Winter-de Groot KM, Majoor CJ, Heijerman HG, de Jonge HR, Hanrahan JW, van der Ent CK, Beekman JM. Vijftigschild LA, et al. Among authors: majoor cj. Eur Respir J. 2016 Sep;48(3):768-79. doi: 10.1183/13993003.01661-2015. Epub 2016 Jul 28. Eur Respir J. 2016. PMID: 27471203 Free article. Clinical Trial.
Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.
Heijerman HGM, McKone EF, Downey DG, Van Braeckel E, Rowe SM, Tullis E, Mall MA, Welter JJ, Ramsey BW, McKee CM, Marigowda G, Moskowitz SM, Waltz D, Sosnay PR, Simard C, Ahluwalia N, Xuan F, Zhang Y, Taylor-Cousar JL, McCoy KS; VX17-445-103 Trial Group. Heijerman HGM, et al. Lancet. 2019 Nov 23;394(10212):1940-1948. doi: 10.1016/S0140-6736(19)32597-8. Epub 2019 Oct 31. Lancet. 2019. PMID: 31679946 Free PMC article. Clinical Trial.
Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.
Middleton PG, Mall MA, Dřevínek P, Lands LC, McKone EF, Polineni D, Ramsey BW, Taylor-Cousar JL, Tullis E, Vermeulen F, Marigowda G, McKee CM, Moskowitz SM, Nair N, Savage J, Simard C, Tian S, Waltz D, Xuan F, Rowe SM, Jain R; VX17-445-102 Study Group. Middleton PG, et al. N Engl J Med. 2019 Nov 7;381(19):1809-1819. doi: 10.1056/NEJMoa1908639. Epub 2019 Oct 31. N Engl J Med. 2019. PMID: 31697873 Free PMC article. Clinical Trial.
Clinical effects of the three CFTR potentiator treatments curcumin, genistein and ivacaftor in patients with the CFTR-S1251N gating mutation.
Berkers G, van der Meer R, van Mourik P, Vonk AM, Kruisselbrink E, Suen SW, Heijerman HG, Majoor CJ, Koppelman GH, Roukema J, Janssens HM, de Rijke YB, Kemper EM, Beekman JM, van der Ent CK, de Jonge HR. Berkers G, et al. Among authors: majoor cj. J Cyst Fibros. 2020 Nov;19(6):955-961. doi: 10.1016/j.jcf.2020.04.014. Epub 2020 Jun 1. J Cyst Fibros. 2020. PMID: 32499204 Free article. Clinical Trial.
Targeted exhaled breath analysis for detection of Pseudomonas aeruginosa in cystic fibrosis patients.
Kos R, Brinkman P, Neerincx AH, Paff T, Gerritsen MG, Lammers A, Kraneveld AD, Heijerman HGM, Janssens HM, Davies JC, Majoor CJ, Weersink EJ, Sterk PJ, Haarman EG, Bos LD, Maitland-van der Zee AH; Amsterdam Mucociliary Clearance Disease (AMCD) Research Group and the Amsterdam UMC Breath Research Group. Kos R, et al. Among authors: majoor cj. J Cyst Fibros. 2022 Jan;21(1):e28-e34. doi: 10.1016/j.jcf.2021.04.015. Epub 2021 May 18. J Cyst Fibros. 2022. PMID: 34016557 Free article. Review.
The long-term safety of chronic azithromycin use in adult patients with cystic fibrosis, evaluating biomarkers for renal function, hepatic function and electrical properties of the heart.
Akkerman-Nijland AM, Möhlmann JE, Akkerman OW, Vd Vaart H, Majoor CJ, Rottier BL, Burgerhof JGM, Hak E, Koppelman GH, Touw DJ. Akkerman-Nijland AM, et al. Among authors: majoor cj. Expert Opin Drug Saf. 2021 Aug;20(8):959-963. doi: 10.1080/14740338.2021.1932814. Epub 2021 Jun 7. Expert Opin Drug Saf. 2021. PMID: 34030570 Free article.
Real-life efficacy and safety of elexacaftor/tezacaftor/ivacaftor on severe cystic fibrosis lung disease patients.
Kos R, Neerincx AH, Fenn DW, Brinkman P, Lub R, Vonk SEM, Roukema J, Reijers MH, Terheggen-Lagro SWJ, Altenburg J, Majoor CJ, Bos LD, Haarman EG, Maitland-van der Zee AH; Amsterdam Mucociliary Clearance Disease (AMCD) Research Group. Kos R, et al. Among authors: majoor cj. Pharmacol Res Perspect. 2022 Dec;10(6):e01015. doi: 10.1002/prp2.1015. Pharmacol Res Perspect. 2022. PMID: 36440690 Free PMC article.
Safety and efficacy of vanzacaftor-tezacaftor-deutivacaftor in adults with cystic fibrosis: randomised, double-blind, controlled, phase 2 trials.
Uluer AZ, MacGregor G, Azevedo P, Indihar V, Keating C, Mall MA, McKone EF, Ramsey BW, Rowe SM, Rubenstein RC, Taylor-Cousar JL, Tullis E, Yonker LM, Chu C, Lam AP, Nair N, Sosnay PR, Tian S, Van Goor F, Viswanathan L, Waltz D, Wang LT, Xi Y, Billings J, Horsley A; VX18-121-101; VX18-561-101 Study Groups. Uluer AZ, et al. Lancet Respir Med. 2023 Jun;11(6):550-562. doi: 10.1016/S2213-2600(22)00504-5. Epub 2023 Feb 23. Lancet Respir Med. 2023. PMID: 36842446 Free PMC article. Clinical Trial.
Quantitative Method for the Analysis of Ivacaftor, Hydroxymethyl Ivacaftor, Ivacaftor Carboxylate, Lumacaftor, and Tezacaftor in Plasma and Sputum Using Liquid Chromatography With Tandem Mass Spectrometry and Its Clinical Applicability.
Vonk SEM, van der Meer-Vos M, Bos LDJ, Neerincx AH, Majoor CJ, Maitland-van der Zee AH, Mathôt RAA, Kemper EM; Amsterdam Mucociliary Clearance Disease (AMCD) research group. Vonk SEM, et al. Among authors: majoor cj. Ther Drug Monit. 2021 Aug 1;43(4):555-563. doi: 10.1097/FTD.0000000000000829. Ther Drug Monit. 2021. PMID: 33165217 Free PMC article.
Tobramycin and vestibulotoxicity: retrospective analysis of four cases.
Vonk SEM, Weersink EJM, Majoor CJ, Kemper EM; Amsterdam Mucociliary Clearance Disease (AMCD) Research Group. Vonk SEM, et al. Among authors: majoor cj. Eur J Hosp Pharm. 2022 Mar;29(e1):e88-e90. doi: 10.1136/ejhpharm-2020-002588. Epub 2021 Mar 22. Eur J Hosp Pharm. 2022. PMID: 33753422 Free PMC article.
Risk of deep vein thrombosis and pulmonary embolism in asthma.
Majoor CJ, Kamphuisen PW, Zwinderman AH, Ten Brinke A, Amelink M, Rijssenbeek-Nouwens L, Sterk PJ, Büller HR, Bel EH. Majoor CJ, et al. Eur Respir J. 2013 Sep;42(3):655-61. doi: 10.1183/09031936.00150312. Epub 2012 Dec 20. Eur Respir J. 2013. PMID: 23258790 Free article.
Activated protein C inhibits neutrophil migration in allergic asthma: a randomised trial.
de Boer JD, Berger M, Majoor CJ, Kager LM, Meijers JC, Terpstra S, Nieuwland R, Boing AN, Lutter R, Wouters D, van Mierlo GJ, Zeerleder SS, Bel EH, van't Veer C, de Vos AF, van der Zee JS, van der Poll T. de Boer JD, et al. Among authors: majoor cj. Eur Respir J. 2015 Dec;46(6):1636-44. doi: 10.1183/13993003.00459-2015. Epub 2015 Sep 17. Eur Respir J. 2015. PMID: 26381519 Free article. Clinical Trial.
Anti-IL-5 in Mild Asthma Alters Rhinovirus-induced Macrophage, B-Cell, and Neutrophil Responses (MATERIAL). A Placebo-controlled, Double-Blind Study.
Sabogal Piñeros YS, Bal SM, van de Pol MA, Dierdorp BS, Dekker T, Dijkhuis A, Brinkman P, van der Sluijs KF, Zwinderman AH, Majoor CJ, Bonta PI, Ravanetti L, Sterk PJ, Lutter R. Sabogal Piñeros YS, et al. Among authors: majoor cj. Am J Respir Crit Care Med. 2019 Feb 15;199(4):508-517. doi: 10.1164/rccm.201803-0461OC. Am J Respir Crit Care Med. 2019. PMID: 30192638 Clinical Trial.
Eosinophils capture viruses, a capacity that is defective in asthma.
Sabogal Piñeros YS, Bal SM, Dijkhuis A, Majoor CJ, Dierdorp BS, Dekker T, Hoefsmit EP, Bonta PI, Picavet D, van der Wel NN, Koenderman L, Sterk PJ, Ravanetti L, Lutter R. Sabogal Piñeros YS, et al. Among authors: majoor cj. Allergy. 2019 Oct;74(10):1898-1909. doi: 10.1111/all.13802. Epub 2019 May 15. Allergy. 2019. PMID: 30934128 Free PMC article.
Effect of C1-inhibitor in adults with mild asthma: A randomized controlled trial.
Yang J, van Engelen TSR, Haak BW, Bonta PI, Majoor CJ, van 't Veer C, de Vos AF, Kemper EM, Lutter R, van Mierlo G, Zeerleder SS, Bel EH, van der Poll T. Yang J, et al. Among authors: majoor cj. Allergy. 2020 Apr;75(4):953-955. doi: 10.1111/all.14053. Epub 2019 Oct 1. Allergy. 2020. PMID: 31535384 Free PMC article. Clinical Trial. No abstract available.
Added value of chest computed tomography in suspected COVID-19: an analysis of 239 patients.
Korevaar DA, Kootte RS, Smits LP, van den Aardweg JG, Bonta PI, Schinkel J, Vigeveno RM, van den Berk IAH, Scheerder MJ, Lemkes BA, Goorhuis A, Beenen LFM, Annema JT; Amsterdam UMC location AMC COVID-19 group. Korevaar DA, et al. Eur Respir J. 2020 Aug 20;56(2):2001377. doi: 10.1183/13993003.01377-2020. Print 2020 Aug. Eur Respir J. 2020. PMID: 32675202 Free PMC article.
The influence of corticosteroids on hemostasis in healthy subjects.
Majoor CJ, Sneeboer MM, de Kievit A, Meijers JC, van der Poll T, Lutter R, Bel EH, Kamphuisen PW. Majoor CJ, et al. J Thromb Haemost. 2016 Apr;14(4):716-23. doi: 10.1111/jth.13265. Epub 2016 Feb 18. J Thromb Haemost. 2016. PMID: 26791678 Free article. Clinical Trial.
Asthma and coagulation.
de Boer JD, Majoor CJ, van 't Veer C, Bel EH, van der Poll T. de Boer JD, et al. Among authors: majoor cj. Blood. 2012 Apr 5;119(14):3236-44. doi: 10.1182/blood-2011-11-391532. Epub 2012 Jan 18. Blood. 2012. PMID: 22262775 Free article. Review.
A rare cause of chylothorax and lymph edema.
Majoor CJ, Aliredjo RP, Dekhuijzen PN, Bulten J, van der Heijden HF. Majoor CJ, et al. J Thorac Oncol. 2007 Mar;2(3):247-8. doi: 10.1097/JTO.0b013e318031bc8a. J Thorac Oncol. 2007. PMID: 17410049 Free article.
Systemic tryptophan and kynurenine catabolite levels relate to severity of rhinovirus-induced asthma exacerbation: a prospective study with a parallel-group design.
van der Sluijs KF, van de Pol MA, Kulik W, Dijkhuis A, Smids BS, van Eijk HW, Karlas JA, Molenkamp R, Wolthers KC, Johnston SL, van der Zee JS, Sterk PJ, Lutter R; RESOLVE research team. van der Sluijs KF, et al. Thorax. 2013 Dec;68(12):1122-30. doi: 10.1136/thoraxjnl-2013-203728. Epub 2013 Jul 23. Thorax. 2013. PMID: 23882022