Nist-Lund C - Search Results

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17 results

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Direct Delivery of Antisense Oligonucleotides to the Middle and Inner Ear Improves Hearing and Balance in Usher Mice.

Lentz JJ, Pan B, Ponnath A, Tran CM, Nist-Lund C, Galvin A, Goldberg H, Robillard KN, Jodelka FM, Farris HE, Huang J, Chen T, Zhu H, Zhou W, Rigo F, Hastings ML, Géléoc GSG. Lentz JJ, et al. Mol Ther. 2020 Dec 2;28(12):2662-2676. doi: 10.1016/j.ymthe.2020.08.002. Epub 2020 Aug 5. Mol Ther. 2020. PMID: 32818431 Free PMC article.

Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1.

Asai Y, Pan B, Nist-Lund C, Galvin A, Lukashkin AN, Lukashkina VA, Chen T, Zhou W, Zhu H, Russell IJ, Holt JR, Géléoc GSG. Asai Y, et al. Sci Rep. 2018 Aug 14;8(1):12124. doi: 10.1038/s41598-018-28958-x. Sci Rep. 2018. PMID: 30108254 Free PMC article.

TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells.

Pan B, Akyuz N, Liu XP, Asai Y, Nist-Lund C, Kurima K, Derfler BH, György B, Limapichat W, Walujkar S, Wimalasena LN, Sotomayor M, Corey DP, Holt JR. Pan B, et al. Neuron. 2018 Aug 22;99(4):736-753.e6. doi: 10.1016/j.neuron.2018.07.033. Neuron. 2018. PMID: 30138589 Free PMC article.

Improved TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders.

Nist-Lund CA, Pan B, Patterson A, Asai Y, Chen T, Zhou W, Zhu H, Romero S, Resnik J, Polley DB, Géléoc GS, Holt JR. Nist-Lund CA, et al. Nat Commun. 2019 Jan 22;10(1):236. doi: 10.1038/s41467-018-08264-w. Nat Commun. 2019. PMID: 30670701 Free PMC article.

Publisher Correction: Improved TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders.

Nist-Lund CA, Pan B, Patterson A, Asai Y, Chen T, Zhou W, Zhu H, Romero S, Resnik J, Polley DB, Géléoc GS, Holt JR. Nist-Lund CA, et al. Nat Commun. 2019 Feb 8;10(1):734. doi: 10.1038/s41467-019-08716-x. Nat Commun. 2019. PMID: 30737404 Free PMC article.

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss.

György B, Nist-Lund C, Pan B, Asai Y, Karavitaki KD, Kleinstiver BP, Garcia SP, Zaborowski MP, Solanes P, Spataro S, Schneider BL, Joung JK, Géléoc GSG, Holt JR, Corey DP. György B, et al. Nat Med. 2019 Jul;25(7):1123-1130. doi: 10.1038/s41591-019-0500-9. Epub 2019 Jul 3. Nat Med. 2019. PMID: 31270503 Free PMC article.

Efficient viral transduction in mouse inner ear hair cells with utricle injection and AAV9-PHP.B.

Lee J, Nist-Lund C, Solanes P, Goldberg H, Wu J, Pan B, Schneider BL, Holt JR. Lee J, et al. Hear Res. 2020 Sep 1;394:107882. doi: 10.1016/j.heares.2020.107882. Epub 2020 Jan 13. Hear Res. 2020. PMID: 31980281 Free article.

Single and Dual Vector Gene Therapy with AAV9-PHP.B Rescues Hearing in Tmc1 Mutant Mice.

Wu J, Solanes P, Nist-Lund C, Spataro S, Shubina-Oleinik O, Marcovich I, Goldberg H, Schneider BL, Holt JR. Wu J, et al. Among authors: nist lund c. Mol Ther. 2021 Mar 3;29(3):973-988. doi: 10.1016/j.ymthe.2020.11.016. Epub 2020 Nov 17. Mol Ther. 2021. PMID: 33212302 Free PMC article.

Advancements in inner ear development, regeneration, and repair through otic organoids.

Nist-Lund C, Kim J, Koehler KR. Nist-Lund C, et al. Curr Opin Genet Dev. 2022 Oct;76:101954. doi: 10.1016/j.gde.2022.101954. Epub 2022 Jul 16. Curr Opin Genet Dev. 2022. PMID: 35853286 Free PMC article. Review.

A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs.

van der Valk WH, van Beelen ESA, Steinhart MR, Nist-Lund C, Osorio D, de Groot JCMJ, Sun L, van Benthem PPG, Koehler KR, Locher H. van der Valk WH, et al. Among authors: nist lund c. Cell Rep. 2023 Jun 27;42(6):112623. doi: 10.1016/j.celrep.2023.112623. Epub 2023 Jun 7. Cell Rep. 2023. PMID: 37289589 Free PMC article.

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

Shubina-Oleinik O, Nist-Lund C, French C, Rockowitz S, Shearer AE, Holt JR. Shubina-Oleinik O, et al. Among authors: nist lund c. Sci Adv. 2021 Dec 17;7(51):eabi7629. doi: 10.1126/sciadv.abi7629. Epub 2021 Dec 15. Sci Adv. 2021. PMID: 34910522 Free PMC article.

Mapping oto-pharyngeal development in a human inner ear organoid model.

Steinhart MR, van der Valk WH, Osorio D, Serdy SA, Zhang J, Nist-Lund C, Kim J, Moncada-Reid C, Sun L, Lee J, Koehler KR. Steinhart MR, et al. Among authors: nist lund c. Development. 2023 Oct 1;150(19):dev201871. doi: 10.1242/dev.201871. Epub 2023 Oct 5. Development. 2023. PMID: 37796037 Free PMC article.

pH regulates potassium conductance and drives a constitutive proton current in human TMEM175.

Zheng W, Shen C, Wang L, Rawson S, Xie WJ, Nist-Lund C, Wu J, Shen Z, Xia S, Holt JR, Wu H, Fu TM. Zheng W, et al. Among authors: nist lund c. Sci Adv. 2022 Mar 25;8(12):eabm1568. doi: 10.1126/sciadv.abm1568. Epub 2022 Mar 25. Sci Adv. 2022. PMID: 35333573 Free PMC article.

Lateral plate mesoderm directs human amnion and ventral skin organoid formation.

Le AP, Kim J, Ma Q, Gim KY, Serdy SA, Lee EH, Shaila ST, Nakajima T, Nist-Lund C, Glass IA, Mai Y, Nuzzi LC, McNamara CT, Labow BI, Sun L, Lee J, Pourquie O, Koehler KR. Le AP, et al. Among authors: nist lund c. bioRxiv [Preprint]. 2025 Nov 6:2025.11.05.685987. doi: 10.1101/2025.11.05.685987. bioRxiv. 2025. PMID: 41278640 Free PMC article. Preprint.

AAV-mediated exon skipping therapy for Usher syndrome, type 2A.

Mauriac SA, Lee J, Zhang J, Jin J, Nist-Lund C, Martin CT, Von Muhlenbrock CR, O'Malley S, Chaves MG, Madison MA, Foster K, Long S, Jacobs C, Kumar SR, Ramirez S, Ichida J, Koehler KR, Holt JR, Géléoc GSG. Mauriac SA, et al. Among authors: nist lund c. Mol Ther. 2026 Jan 7;34(1):179-202. doi: 10.1016/j.ymthe.2025.09.038. Epub 2025 Sep 23. Mol Ther. 2026. PMID: 40994011

Generation and characterization of vestibular inner ear organoids from human pluripotent stem cells.

van der Valk WH, Nist-Lund C, Zhang J, Perea C, Jin J, Gim KY, Steinhart MR, Lee J, Koehler KR. van der Valk WH, et al. Among authors: nist lund c. Nat Protoc. 2025 Jun 2:10.1038/s41596-025-01191-3. doi: 10.1038/s41596-025-01191-3. Online ahead of print. Nat Protoc. 2025. PMID: 40457100 Free PMC article. Review.

A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs.

van der Valk WH, van Beelen ESA, Steinhart MR, Nist-Lund C, Osorio D, de Groot JCMJ, Sun L, van Benthem PPG, Koehler KR, Locher H. van der Valk WH, et al. Among authors: nist lund c. Cell Rep. 2023 Dec 26;42(12):113527. doi: 10.1016/j.celrep.2023.113527. Epub 2023 Nov 29. Cell Rep. 2023. PMID: 38032795 Free PMC article. No abstract available.

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