Novelli EM - Search Results

1

Machine-learning algorithms for predicting hospital re-admissions in sickle cell disease.

Patel A, Gan K, Li AA, Weiss J, Nouraie M, Tayur S, Novelli EM. Patel A, et al. Among authors: novelli em. Br J Haematol. 2021 Jan;192(1):158-170. doi: 10.1111/bjh.17107. Epub 2020 Nov 10. Br J Haematol. 2021. PMID: 33169861 Free article.

2

Clinical predictors of severe malarial anaemia in a holoendemic Plasmodium falciparum transmission area.

Novelli EM, Hittner JB, Davenport GC, Ouma C, Were T, Obaro S, Kaplan S, Ong'echa JM, Perkins DJ. Novelli EM, et al. Br J Haematol. 2010 Jun;149(5):711-21. doi: 10.1111/j.1365-2141.2010.08147.x. Epub 2010 Apr 16. Br J Haematol. 2010. PMID: 20408849 Free PMC article.

3

Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom.

Sachdev V, Kato GJ, Gibbs JS, Barst RJ, Machado RF, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli EM, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Taylor JG 6th, Hannoush H, Goldsmith JC, Gladwin MT, Gordeuk VR; Walk-PHASST Investigators. Sachdev V, et al. Among authors: novelli em. Circulation. 2011 Sep 27;124(13):1452-60. doi: 10.1161/CIRCULATIONAHA.111.032920. Epub 2011 Sep 6. Circulation. 2011. PMID: 21900080 Free PMC article. Clinical Trial.

4

Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates.

Novelli EM, Kato GJ, Ragni MV, Zhang Y, Hildesheim ME, Nouraie M, Barge S, Meyer MP, Hassett AC, Gordeuk VR, Gladwin MT, Isenberg JS. Novelli EM, et al. Am J Hematol. 2012 Mar;87(3):326-30. doi: 10.1002/ajh.22274. Epub 2012 Feb 8. Am J Hematol. 2012. PMID: 22318901 Free PMC article.

5

Pulmonary embolism in sickle cell disease: a case-control study.

Novelli EM, Huynh C, Gladwin MT, Moore CG, Ragni MV. Novelli EM, et al. J Thromb Haemost. 2012 May;10(5):760-6. doi: 10.1111/j.1538-7836.2012.04697.x. J Thromb Haemost. 2012. PMID: 22417249 Free PMC article.

6

The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe.

Nouraie M, Lee JS, Zhang Y, Kanias T, Zhao X, Xiong Z, Oriss TB, Zeng Q, Kato GJ, Gibbs JS, Hildesheim ME, Sachdev V, Barst RJ, Machado RF, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Goldsmith JC, Gordeuk VR, Gladwin MT; Walk-PHASST Investigators and Patients. Nouraie M, et al. Haematologica. 2013 Mar;98(3):464-72. doi: 10.3324/haematol.2012.068965. Epub 2012 Sep 14. Haematologica. 2013. PMID: 22983573 Free PMC article.

7

Risk factors for death in 632 patients with sickle cell disease in the United States and United Kingdom.

Gladwin MT, Barst RJ, Gibbs JS, Hildesheim M, Sachdev V, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Berman Rosenzweig E, Badesch DB, Lanzkron S, Castro OL, Taylor JG 6th, Goldsmith JC, Kato GJ, Gordeuk VR, Machado RF; walk-PHaSST Investigators and Patients. Gladwin MT, et al. PLoS One. 2014 Jul 2;9(7):e99489. doi: 10.1371/journal.pone.0099489. eCollection 2014. PLoS One. 2014. PMID: 24988120 Free PMC article. Clinical Trial.

8

Elevated pulse pressure is associated with hemolysis, proteinuria and chronic kidney disease in sickle cell disease.

Novelli EM, Hildesheim M, Rosano C, Vanderpool R, Simon M, Kato GJ, Gladwin MT. Novelli EM, et al. PLoS One. 2014 Dec 5;9(12):e114309. doi: 10.1371/journal.pone.0114309. eCollection 2014. PLoS One. 2014. PMID: 25478953 Free PMC article. Clinical Trial.

9

Crises in Sickle Cell Disease.

Novelli EM, Gladwin MT. Novelli EM, et al. Chest. 2016 Apr;149(4):1082-93. doi: 10.1016/j.chest.2015.12.016. Epub 2015 Dec 28. Chest. 2016. PMID: 26836899 Free PMC article. Review.

10

Rates and risk factors of hypertension in adolescents and adults with sickle cell anaemia in Tanzania: 10 years' experience.

Makubi A, Mmbando BP, Novelli EM, Lwakatare J, Soka D, Marik H, Tibarazwa K, Ngaeje M, Newton CR, Gladwin MT, Makani J. Makubi A, et al. Among authors: novelli em. Br J Haematol. 2017 Jun;177(6):930-937. doi: 10.1111/bjh.14330. Epub 2016 Sep 21. Br J Haematol. 2017. PMID: 27650269 Free PMC article.

11

The association of smartphone-based activity space measures with cognitive functioning and pain sickle cell disease.

Jonassaint CR, Birenboim A, Jorgensen DR, Novelli EM, Rosso AL. Jonassaint CR, et al. Among authors: novelli em. Br J Haematol. 2018 May;181(3):395-397. doi: 10.1111/bjh.14598. Epub 2017 Jul 17. Br J Haematol. 2018. PMID: 28714077 Free PMC article. No abstract available.

12

Pathophysiology of Sickle Cell Disease.

Sundd P, Gladwin MT, Novelli EM. Sundd P, et al. Among authors: novelli em. Annu Rev Pathol. 2019 Jan 24;14:263-292. doi: 10.1146/annurev-pathmechdis-012418-012838. Epub 2018 Oct 17. Annu Rev Pathol. 2019. PMID: 30332562 Free PMC article. Review.

13

Measuring success: utility of biomarkers in sickle cell disease clinical trials and care.

Kalpatthi R, Novelli EM. Kalpatthi R, et al. Among authors: novelli em. Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):482-492. doi: 10.1182/asheducation-2018.1.482. Hematology Am Soc Hematol Educ Program. 2018. PMID: 30504349 Free PMC article. Review.

14

Acute kidney injury in paediatric patients with sickle cell disease is associated with increased morbidity and resource utilization.

McCormick M, Richardson T, Warady BA, Novelli EM, Kalpatthi R. McCormick M, et al. Among authors: novelli em. Br J Haematol. 2020 May;189(3):559-565. doi: 10.1111/bjh.16384. Epub 2020 Feb 6. Br J Haematol. 2020. PMID: 32030722 Free article.

15

Editorial commentary: Sickle cell disease: Diagnosing the heart of the matter.

Caughey MC, Novelli EM. Caughey MC, et al. Among authors: novelli em. Trends Cardiovasc Med. 2021 Apr;31(3):194-195. doi: 10.1016/j.tcm.2020.02.007. Epub 2020 Feb 28. Trends Cardiovasc Med. 2021. PMID: 32192822 No abstract available.

16

Extinguishing the fire in sickle cell anemia.

Novelli EM. Novelli EM. Blood. 2022 Apr 28;139(17):2578-2580. doi: 10.1182/blood.2022015910. Blood. 2022. PMID: 35482344 Free article. No abstract available.

17

Prevalence and outcomes of dehydration in adults with sickle cell trait: the Atherosclerosis Risk in Communities (ARIC) study.

Caughey MC, Derebail VK, Carden MA, Novelli EM, Lutsey PL, Key NS, Kshirsagar AV, Heiss G. Caughey MC, et al. Among authors: novelli em. Br J Haematol. 2022 Jul;198(2):397-400. doi: 10.1111/bjh.18221. Epub 2022 May 3. Br J Haematol. 2022. PMID: 35510344 No abstract available.

18

Molecular mechanisms of hepatic dysfunction in sickle cell disease: lessons from Townes mouse model.

Pradhan-Sundd T, Kato GJ, Novelli EM. Pradhan-Sundd T, et al. Among authors: novelli em. Am J Physiol Cell Physiol. 2022 Aug 1;323(2):C494-C504. doi: 10.1152/ajpcell.00175.2022. Epub 2022 Jun 27. Am J Physiol Cell Physiol. 2022. PMID: 35759437 Free PMC article. Review.

19

Platelet bioenergetic screen in sickle cell patients reveals mitochondrial complex V inhibition, which contributes to platelet activation.

Cardenes N, Corey C, Geary L, Jain S, Zharikov S, Barge S, Novelli EM, Shiva S. Cardenes N, et al. Among authors: novelli em. Blood. 2014 May 1;123(18):2864-72. doi: 10.1182/blood-2013-09-529420. Epub 2014 Mar 27. Blood. 2014. PMID: 24677541 Free PMC article.

20

Quantitative microfluidic fluorescence microscopy to study vaso-occlusion in sickle cell disease.

Jimenez MA, Tutuncuoglu E, Barge S, Novelli EM, Sundd P. Jimenez MA, et al. Among authors: novelli em. Haematologica. 2015 Oct;100(10):e390-3. doi: 10.3324/haematol.2015.126631. Epub 2015 May 14. Haematologica. 2015. PMID: 25975836 Free PMC article. No abstract available.

21

Brain venular pattern by 7T MRI correlates with memory and haemoglobin in sickle cell anaemia.

Novelli EM, Elizabeth Sarles C, Jay Aizenstein H, Ibrahim TS, Butters MA, Connelly Ritter A, Erickson KI, Rosano C. Novelli EM, et al. Psychiatry Res. 2015 Jul 30;233(1):18-22. doi: 10.1016/j.pscychresns.2015.04.005. Epub 2015 Apr 25. Psychiatry Res. 2015. PMID: 26002434 Free PMC article.

22

Rationale and design of mDOT-HuA study: a randomized trial to assess the effect of mobile-directly observed therapy on adherence to hydroxyurea in adults with sickle cell anemia in Tanzania.

Makubi A, Sasi P, Ngaeje M, Novelli EM, Mmbando BP, Gladwin MT, Makani J. Makubi A, et al. Among authors: novelli em. BMC Med Res Methodol. 2016 Oct 18;16(1):140. doi: 10.1186/s12874-016-0245-9. BMC Med Res Methodol. 2016. PMID: 27756209 Free PMC article.

23

Thrombospondin-1 gene polymorphism is associated with estimated pulmonary artery pressure in patients with sickle cell anemia.

Jacob SA, Novelli EM, Isenberg JS, Garrett ME, Chu Y, Soldano K, Ataga KI, Telen MJ, Ashley-Koch A, Gladwin MT, Zhang Y, Kato GJ. Jacob SA, et al. Among authors: novelli em. Am J Hematol. 2017 Mar;92(3):E31-E34. doi: 10.1002/ajh.24635. Epub 2017 Feb 3. Am J Hematol. 2017. PMID: 28033687 Free PMC article. Clinical Trial. No abstract available.

24

Glycoprotein Ibα inhibitor (CCP-224) prevents neutrophil-platelet aggregation in Sickle Cell Disease.

Jimenez MA, Novelli E, Shaw GD, Sundd P. Jimenez MA, et al. Blood Adv. 2017 Sep 12;1(20):1712-1716. doi: 10.1182/bloodadvances.2017006742. Blood Adv. 2017. PMID: 28966995 Free PMC article.

25

Disease severity and slower psychomotor speed in adults with sickle cell disease.

Jorgensen DR, Metti A, Butters MA, Mettenburg JM, Rosano C, Novelli EM. Jorgensen DR, et al. Among authors: novelli em. Blood Adv. 2017 Sep 14;1(21):1790-1795. doi: 10.1182/bloodadvances.2017008219. eCollection 2017 Sep 26. Blood Adv. 2017. PMID: 29296825 Free PMC article.

26

Decoding the role of SOD2 in sickle cell disease.

Dosunmu-Ogunbi AM, Wood KC, Novelli EM, Straub AC. Dosunmu-Ogunbi AM, et al. Among authors: novelli em. Blood Adv. 2019 Sep 10;3(17):2679-2687. doi: 10.1182/bloodadvances.2019000527. Blood Adv. 2019. PMID: 31506286 Free PMC article. Review.

27

P-selectin deficiency promotes liver senescence in sickle cell disease mice.

Vats R, Kaminski TW, Ju EM, Brozska T, Tutuncuoglu E, Tejero J, Novelli EM, Sundd P, Pradhan-Sundd T. Vats R, et al. Among authors: novelli em. Blood. 2021 May 13;137(19):2676-2680. doi: 10.1182/blood.2020009779. Blood. 2021. PMID: 33619560 Free PMC article.

28

Liver-to-lung microembolic NETs promote gasdermin D-dependent inflammatory lung injury in sickle cell disease.

Vats R, Kaminski TW, Brzoska T, Leech JA, Tutuncuoglu E, Katoch O, Jonassaint J, Tejero J, Novelli EM, Pradhan-Sundd T, Gladwin MT, Sundd P. Vats R, et al. Among authors: novelli em. Blood. 2022 Sep 1;140(9):1020-1037. doi: 10.1182/blood.2021014552. Blood. 2022. PMID: 35737916 Free PMC article.

29

Comprehensive assessment of cognitive function in adults with moderate and severe sickle cell disease.

Portela GT, Butters MA, Brooks MM, Candra L, Rosano C, Novelli EM. Portela GT, et al. Among authors: novelli em. Am J Hematol. 2022 Sep;97(9):E344-E346. doi: 10.1002/ajh.26643. Epub 2022 Jul 1. Am J Hematol. 2022. PMID: 35749262 Free PMC article. No abstract available.

30

Is CBD ready for prime time in sickle cell disease?

Curtis SA, Novelli EM. Curtis SA, et al. Among authors: novelli em. Blood. 2023 Jan 12;141(2):132-133. doi: 10.1182/blood.2022018393. Blood. 2023. PMID: 36633888 Free PMC article. No abstract available.

31

Cognitive functioning in children from Nigeria with sickle cell anemia.

Oluwole OB, Noll RB, Winger DG, Akinyanju O, Novelli EM. Oluwole OB, et al. Among authors: novelli em. Pediatr Blood Cancer. 2016 Nov;63(11):1990-7. doi: 10.1002/pbc.26126. Epub 2016 Jul 9. Pediatr Blood Cancer. 2016. PMID: 27393914 Free PMC article.

32

Integrin VLA-4 as a PET imaging biomarker of hyper-adhesion in transgenic sickle mice.

Perkins LA, Nyiranshuti L, Little-Ihrig L, Latoche JD, Day KE, Zhu Q, Tavakoli S, Sundd P, Novelli EM, Anderson CJ. Perkins LA, et al. Among authors: novelli em. Blood Adv. 2020 Sep 8;4(17):4102-4112. doi: 10.1182/bloodadvances.2020002642. Blood Adv. 2020. PMID: 32882004 Free PMC article.

33

Endothelial superoxide dismutase 2 is decreased in sickle cell disease and regulates fibronectin processing.

Dosunmu-Ogunbi A, Yuan S, Shiwarski DJ, Tashman JW, Reynolds M, Feinberg A, Novelli EM, Shiva S, Straub AC. Dosunmu-Ogunbi A, et al. Among authors: novelli em. Function (Oxf). 2022 Feb 17;3(2):zqac005. doi: 10.1093/function/zqac005. eCollection 2022. Function (Oxf). 2022. PMID: 35274104 Free PMC article.

34

Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension.

Rogers NM, Yao M, Sembrat J, George MP, Knupp H, Ross M, Sharifi-Sanjani M, Milosevic J, St Croix C, Rajkumar R, Frid MG, Hunter KS, Mazzaro L, Novelli EM, Stenmark KR, Gladwin MT, Ahmad F, Champion HC, Isenberg JS. Rogers NM, et al. Among authors: novelli em. Pulm Circ. 2013 Dec;3(4):936-51. doi: 10.1086/674754. Pulm Circ. 2013. PMID: 25006410 Free PMC article.

35

Can Neuroimaging Markers of Vascular Pathology Explain Cognitive Performance in Adults With Sickle Cell Anemia? A review of the Literature.

Jorgensen DR, Rosano C, Novelli EM. Jorgensen DR, et al. Among authors: novelli em. Hemoglobin. 2016 Nov;40(6):381-387. doi: 10.1080/03630269.2016.1242493. Hemoglobin. 2016. PMID: 27689914 Free PMC article. Review.

36

Vascular TSP1-CD47 signaling promotes sickle cell-associated arterial vasculopathy and pulmonary hypertension in mice.

Novelli EM, Little-Ihrig L, Knupp HE, Rogers NM, Yao M, Baust JJ, Meijles D, St Croix CM, Ross MA, Pagano PJ, DeVallance ER, Miles G, Potoka KP, Isenberg JS, Gladwin MT. Novelli EM, et al. Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1;316(6):L1150-L1164. doi: 10.1152/ajplung.00302.2018. Epub 2019 Mar 20. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30892078 Free PMC article.

37

Analysis of hippocampal subfields in sickle cell disease using ultrahigh field MRI.

Santini T, Koo M, Farhat N, Campos VP, Alkhateeb S, Vieira MAC, Butters MA, Rosano C, Aizenstein HJ, Mettenburg J, Novelli EM, Ibrahim TS. Santini T, et al. Among authors: novelli em. Neuroimage Clin. 2021;30:102655. doi: 10.1016/j.nicl.2021.102655. Epub 2021 Apr 3. Neuroimage Clin. 2021. PMID: 34215139 Free PMC article.

38

Genetics of bleeding disorders in women.

Novelli EM, Ragni MV. Novelli EM, et al. Semin Thromb Hemost. 2008 Sep;34(6):509-19. doi: 10.1055/s-0028-1103362. Epub 2008 Nov 28. Semin Thromb Hemost. 2008. PMID: 19085650 Review.

39

Chest pain, dyspnea, petechiae, and melena in a 58-year-old woman - what is it?

Mehta RS, Ragni MV, Novelli EM. Mehta RS, et al. Among authors: novelli em. Platelets. 2013;24(5):415-8. doi: 10.3109/09537104.2012.699642. Epub 2012 Jun 27. Platelets. 2013. PMID: 22738440 No abstract available.

40

Activated CD47 regulates multiple vascular and stress responses: implications for acute kidney injury and its management.

Rogers NM, Yao M, Novelli EM, Thomson AW, Roberts DD, Isenberg JS. Rogers NM, et al. Among authors: novelli em. Am J Physiol Renal Physiol. 2012 Oct 15;303(8):F1117-25. doi: 10.1152/ajprenal.00359.2012. Epub 2012 Aug 8. Am J Physiol Renal Physiol. 2012. PMID: 22874763 Free PMC article. Review.

41

Phase II prospective open-label trial of recombinant interleukin-11 in desmopressin-unresponsive von Willebrand disease and mild or moderate haemophilia A.

Ragni MV, Novelli EM, Murshed A, Merricks EP, Kloos MT, Nichols TC. Ragni MV, et al. Among authors: novelli em. Thromb Haemost. 2013 Feb;109(2):248-54. doi: 10.1160/TH12-06-0447. Epub 2012 Dec 13. Thromb Haemost. 2013. PMID: 23238591 Free PMC article. Clinical Trial.

42

Unraveling restrictive chronic lung disease in sickle cell disease.

Jain S, Gladwin MT, Novelli EM. Jain S, et al. Among authors: novelli em. Int J Tuberc Lung Dis. 2013 Sep;17(9):1123-4. doi: 10.5588/ijtld.13.0509. Int J Tuberc Lung Dis. 2013. PMID: 23928164 Free PMC article. No abstract available.

43

Vasculopathy, inflammation, and blood flow in leg ulcers of patients with sickle cell anemia.

Minniti CP, Delaney KM, Gorbach AM, Xu D, Lee CC, Malik N, Koroulakis A, Antalek M, Maivelett J, Peters-Lawrence M, Novelli EM, Lanzkron SM, Axelrod KC, Kato GJ. Minniti CP, et al. Among authors: novelli em. Am J Hematol. 2014 Jan;89(1):1-6. doi: 10.1002/ajh.23571. Epub 2013 Sep 19. Am J Hematol. 2014. PMID: 23963836 Free PMC article.

44

Thrombospondin-1 inhibits ADAMTS13 activity in sickle cell disease.

Novelli EM, Kato GJ, Hildesheim ME, Barge S, Meyer MP, Lozier J, Hassett AC, Ragni MV, Isenberg JS, Gladwin MT. Novelli EM, et al. Haematologica. 2013 Nov;98(11):e132-4. doi: 10.3324/haematol.2013.092635. Haematologica. 2013. PMID: 24186313 Free PMC article. No abstract available.

45

Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury.

Yao M, Rogers NM, Csányi G, Rodriguez AI, Ross MA, St Croix C, Knupp H, Novelli EM, Thomson AW, Pagano PJ, Isenberg JS. Yao M, et al. Among authors: novelli em. J Am Soc Nephrol. 2014 Jun;25(6):1171-86. doi: 10.1681/ASN.2013040433. Epub 2014 Feb 7. J Am Soc Nephrol. 2014. PMID: 24511121 Free PMC article.

46

The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1.

Meijles DN, Sahoo S, Al Ghouleh I, Amaral JH, Bienes-Martinez R, Knupp HE, Attaran S, Sembrat JC, Nouraie SM, Rojas MM, Novelli EM, Gladwin MT, Isenberg JS, Cifuentes-Pagano E, Pagano PJ. Meijles DN, et al. Among authors: novelli em. Sci Signal. 2017 Oct 17;10(501):eaaj1784. doi: 10.1126/scisignal.aaj1784. Sci Signal. 2017. PMID: 29042481 Free PMC article.

47

Experimental intravascular hemolysis induces hemodynamic and pathological pulmonary hypertension: association with accelerated purine metabolism.

Bilan VP, Schneider F, Novelli EM, Kelley EE, Shiva S, Gladwin MT, Jackson EK, Tofovic SP. Bilan VP, et al. Among authors: novelli em. Pulm Circ. 2018 Jul-Sep;8(3):2045894018791557. doi: 10.1177/2045894018791557. Epub 2018 Jul 13. Pulm Circ. 2018. PMID: 30003836 Free PMC article.

48

Unfractionated heparin in acute chest syndrome: a pilot feasibility randomized controlled trial of unfractionated heparin vs. standard of care in acute chest syndrome.

Seaman CD, Novelli E, De Castro L, Ragni MV. Seaman CD, et al. Pilot Feasibility Stud. 2020 Nov 10;6(1):174. doi: 10.1186/s40814-020-00715-w. Pilot Feasibility Stud. 2020. PMID: 33292674 Free PMC article.

49

Defenestrated endothelium delays liver-directed gene transfer in hemophilia A mice.

Kaminski TW, Ju EM, Gudapati S, Vats R, Arshad S, Dubey RK, Katoch O, Tutuncuoglu E, Frank J, Brzoska T, Stolz DB, Watkins SC, Chan SY, Ragni MV, Novelli EM, Sundd P, Pradhan-Sundd T. Kaminski TW, et al. Among authors: novelli em. Blood Adv. 2022 Jun 28;6(12):3729-3734. doi: 10.1182/bloodadvances.2021006388. Blood Adv. 2022. PMID: 35427414 Free PMC article.

50

Point of care ultrasound detection of thrombus straddling a patent foramen ovale in a patient with acute chest syndrome.

Gorgone M, Novelli EM, Patel S, Lamberty PE, De Castro LM, Gladwin MT, Maximous SI. Gorgone M, et al. Among authors: novelli em. Respir Med Case Rep. 2022 Aug 8;39:101724. doi: 10.1016/j.rmcr.2022.101724. eCollection 2022. Respir Med Case Rep. 2022. PMID: 36017251 Free PMC article.

51

A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease.

Wun T, Soulieres D, Frelinger AL, Krishnamurti L, Novelli EM, Kutlar A, Ataga KI, Knupp CL, McMahon LE, Strouse JJ, Zhou C, Heath LE, Nwachuku CE, Jakubowski JA, Riesmeyer JS, Winters KJ. Wun T, et al. Among authors: novelli em. J Hematol Oncol. 2013 Feb 17;6:17. doi: 10.1186/1756-8722-6-17. J Hematol Oncol. 2013. PMID: 23414938 Free PMC article. Clinical Trial.

52

First successful lung transplantation for sickle cell disease with severe pulmonary arterial hypertension and pulmonary veno-occlusive disease.

George MP, Novelli EM, Shigemura N, Simon MA, Feingold B, Krishnamurti L, Morrell MR, Gries CG, Haider S, Johnson BA, Crespo MM, Bhama JK, Bermudez C, Yousem SA, Toyoda Y, Champion HC, Pilewski JM, Gladwin MT. George MP, et al. Among authors: novelli em. Pulm Circ. 2013 Dec;3(4):952-8. doi: 10.1086/674749. Pulm Circ. 2013. PMID: 25006411 Free PMC article.

53

TSP1-CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction.

Rogers NM, Sharifi-Sanjani M, Yao M, Ghimire K, Bienes-Martinez R, Mutchler SM, Knupp HE, Baust J, Novelli EM, Ross M, St Croix C, Kutten JC, Czajka CA, Sembrat JC, Rojas M, Labrousse-Arias D, Bachman TN, Vanderpool RR, Zuckerbraun BS, Champion HC, Mora AL, Straub AC, Bilonick RA, Calzada MJ, Isenberg JS. Rogers NM, et al. Among authors: novelli em. Cardiovasc Res. 2017 Jan;113(1):15-29. doi: 10.1093/cvr/cvw218. Epub 2016 Oct 13. Cardiovasc Res. 2017. PMID: 27742621 Free PMC article.

54

COVID-19 and SCA: an old friend comes to the rescue.

Novelli EM. Novelli EM. Blood. 2020 May 28;135(22):1925-1926. doi: 10.1182/blood.2020006442. Blood. 2020. PMID: 32463890 Free PMC article. No abstract available.

55

First report of ⁶⁸Ga-PRGD2 PET/MRI molecular imaging of vaso-occlusion in a patient with sickle cell disease.

Novelli EM, Moon CH, Pham TA, Perkins LA, Little-Ihrig L, Tavakoli S, Mason NS, Lang L, Chen X, Laymon CM, Gladwin MT, Anderson CJ. Novelli EM, et al. BJR Case Rep. 2020 Jun 15;6(4):20200024. doi: 10.1259/bjrcr.20200024. eCollection 2020 Dec 1. BJR Case Rep. 2020. PMID: 33299586 Free PMC article.

56

Inducing Vascular Grammars for Anomaly Classification in Brain Angiograms.

Whiting ME, Mettenburg J, Novelli EM, Santini T, Martins T, Ibrahim TS, LeDuc PR, Cagan J. Whiting ME, et al. Among authors: novelli em. J Eng Sci Med Diagn Ther. 2022 May 1;5(2):021002. doi: 10.1115/1.4053424. Epub 2022 Feb 23. J Eng Sci Med Diagn Ther. 2022. PMID: 35833206 Free PMC article.

57

Validation of the NIH Toolbox-Cognition Battery against legacy neurocognitive measures in adults with cognitive impairments: An exploratory analysis.

Kringle EA, Novelli EM, Butters MA, Skidmore ER. Kringle EA, et al. Among authors: novelli em. J Int Neuropsychol Soc. 2023 Jun;29(5):472-479. doi: 10.1017/S1355617722000406. Epub 2022 Sep 5. J Int Neuropsychol Soc. 2023. PMID: 36062530 Free PMC article.

58

Knee pain: ACL, MCL, or CML?

Novelli EM, Redner RL. Novelli EM, et al. Blood. 2010 Jul 1;115(26):5287. doi: 10.1182/blood-2009-04-190819. Blood. 2010. PMID: 20614568 Free article. No abstract available.

59

Venous thromboembolism in cirrhosis.

Yang ZJ, Costa KA, Novelli EM, Smith RE. Yang ZJ, et al. Among authors: novelli em. Clin Appl Thromb Hemost. 2014 Mar;20(2):169-78. doi: 10.1177/1076029612461846. Epub 2012 Oct 17. Clin Appl Thromb Hemost. 2014. PMID: 23076776 Free PMC article. Review.

60

Targeting P-Selectin Adhesion Molecule in Molecular Imaging: P-Selectin Expression as a Valuable Imaging Biomarker of Inflammation in Cardiovascular Disease.

Perkins LA, Anderson CJ, Novelli EM. Perkins LA, et al. Among authors: novelli em. J Nucl Med. 2019 Dec;60(12):1691-1697. doi: 10.2967/jnumed.118.225169. Epub 2019 Oct 10. J Nucl Med. 2019. PMID: 31601694 Free PMC article. Review.

61

Chaudhary R, Bashline M, Novelli EM, Bliden KP, Tantry US, Olafiranye O, Rahman A, Gurbel PA, Pacella JJ. Chaudhary R, et al. Among authors: novelli em. Int J Cardiol. 2022 Dec 15;369:1-4. doi: 10.1016/j.ijcard.2022.07.050. Epub 2022 Aug 1. Int J Cardiol. 2022. PMID: 35926644

62

The Consortium on Newborn Screening in Africa for sickle cell disease: study rationale and methodology.

Green NS, Zapfel A, Nnodu OE, Franklin P, Tubman VN, Chirande L, Kiyaga C, Chunda-Liyoka C, Awuonda B, Ohene-Frempong K, Inusa BPD, Ware RE, Odame I, Ambrose EE, Dogara LG, Oron AP, Willett C, Thompson AA, Berliner N, Coetzer TL, Novelli EM. Green NS, et al. Among authors: novelli em. Blood Adv. 2022 Dec 27;6(24):6187-6197. doi: 10.1182/bloodadvances.2022007698. Blood Adv. 2022. PMID: 36264096 Free PMC article.

63

Gene therapy for the lysosomal storage disorders.

Cabrera-Salazar MA, Novelli E, Barranger JA. Cabrera-Salazar MA, et al. Curr Opin Mol Ther. 2002 Aug;4(4):349-58. Curr Opin Mol Ther. 2002. PMID: 12222873 Review.

64

Retrovirus-mediated gene transfer to human hematopoietic stem cells.

Swaney WP, Novelli EM, Bahnson AB, Barranger JA. Swaney WP, et al. Among authors: novelli em. Methods Mol Med. 2002;69:187-202. doi: 10.1385/1-59259-141-8:187. Methods Mol Med. 2002. PMID: 11987778 No abstract available.

65

Reply to: Among patients with MINOCA women versus men have the increased risks of MACE and stroke?

Chaudhary R, Bashline M, Novelli EM, Bliden KP, Tantry US, Olafiranye O, Nouraie SM, Gurbel PA, Pacella JJ. Chaudhary R, et al. Among authors: novelli em. Int J Cardiol. 2023 Jan 15;371:80-81. doi: 10.1016/j.ijcard.2022.10.005. Epub 2022 Oct 7. Int J Cardiol. 2023. PMID: 36209769 No abstract available.

66

It's high time to turn the spotlight on HbSC disease.

Oluwole O, Novelli EM. Oluwole O, et al. Among authors: novelli em. Blood Adv. 2023 Jul 11;7(13):3320-3322. doi: 10.1182/bloodadvances.2023009993. Blood Adv. 2023. PMID: 37432698 Free PMC article. No abstract available.

67

Comparison of culture-dependent and -independent methods for bacterial community monitoring during Montasio cheese manufacturing.

Carraro L, Maifreni M, Bartolomeoli I, Martino ME, Novelli E, Frigo F, Marino M, Cardazzo B. Carraro L, et al. Res Microbiol. 2011 Apr;162(3):231-9. doi: 10.1016/j.resmic.2011.01.002. Epub 2011 Jan 22. Res Microbiol. 2011. PMID: 21262359 Free article.

68

Investigating the troublesome relationship between the cow milk and human health.

Gabai G, Novelli E. Gabai G, et al. Res Vet Sci. 2018 Oct;120:1-3. doi: 10.1016/j.rvsc.2018.08.003. Epub 2018 Aug 22. Res Vet Sci. 2018. PMID: 30144621 No abstract available.

69

Riociguat in patients with sickle cell disease and hypertension or proteinuria (STERIO-SCD): a randomised, double-blind, placebo controlled, phase 1-2 trial.

Gladwin MT, Gordeuk VR, Desai PC, Minniti C, Novelli EM, Morris CR, Ataga KI, De Castro L, Curtis SA, El Rassi F, Ford HJ, Harrington T, Klings ES, Lanzkron S, Liles D, Little J, Nero A, Smith W, Taylor JG 6th, Baptiste A, Hagar W, Kanter J, Kinzie A, Martin T, Rafique A, Telen MJ, Lalama CM, Kato GJ, Abebe KZ. Gladwin MT, et al. Among authors: novelli em. Lancet Haematol. 2024 Mar 27:S2352-3026(24)00045-0. doi: 10.1016/S2352-3026(24)00045-0. Online ahead of print. Lancet Haematol. 2024. PMID: 38554715

70

Warm autoimmune hemolytic anemia and hemophagocytic lymphohistiocytosis/macrophage activation syndrome occurring after COVID19 infection and administration of Casirivimab + Imdevimab (COVID19 monoclonal antibody).

Swartz AW, Novelli EM. Swartz AW, et al. Among authors: novelli em. Clin Case Rep. 2024 Feb 12;12(2):e8426. doi: 10.1002/ccr3.8426. eCollection 2024 Feb. Clin Case Rep. 2024. PMID: 38348150 Free PMC article.

71

Use of Disease-Modifying Treatments in Patients With Sickle Cell Disease.

Newman TV, Yang J, Suh K, Jonassaint CR, Kane-Gill SL, Novelli EM. Newman TV, et al. Among authors: novelli em. JAMA Netw Open. 2023 Nov 1;6(11):e2344546. doi: 10.1001/jamanetworkopen.2023.44546. JAMA Netw Open. 2023. PMID: 37991760 Free PMC article.

72

Impaired hemoglobin clearance by sinusoidal endothelium promotes vaso-occlusion and liver injury in sickle cell disease.

Kaminski TW, Katoch O, Li Z, Hanway CB, Dubey RK, Alagbe A, Brzoska T, Zhang H, Sundd P, Kato GJ, Novelli EM, Pradhan-Sundd T. Kaminski TW, et al. Among authors: novelli em. Haematologica. 2023 Nov 9. doi: 10.3324/haematol.2023.283792. Online ahead of print. Haematologica. 2023. PMID: 37941440 Free article.

73

Targeted imaging of very late antigen-4 for noninvasive assessment of lung inflammation-fibrosis axis.

Zhu Q, Barnes CE, Mannes PZ, Latoche JD, Day KE, Nedrow JR, Novelli EM, Anderson CJ, Tavakoli S. Zhu Q, et al. Among authors: novelli em. EJNMMI Res. 2023 Jun 5;13(1):55. doi: 10.1186/s13550-023-01006-0. EJNMMI Res. 2023. PMID: 37273103 Free PMC article.

74

White-matter abnormalities and cognitive dysfunction are linked to astrocyte activation in sickle mice.

Hazra R, Pu H, Foley LM, Little-Ihrig L, Hitchens TK, Ghosh S, Ofori-Acquah SF, Hu X, Novelli EM. Hazra R, et al. Among authors: novelli em. PNAS Nexus. 2023 May 2;2(5):pgad149. doi: 10.1093/pnasnexus/pgad149. eCollection 2023 May. PNAS Nexus. 2023. PMID: 37215630 Free PMC article.

75

Insulin-like Growth Factor-1 Prevents Hypoxia/Reoxygenation-Induced White Matter Injury in Sickle Cell Mice.

Hazra R, Hubert H, Little-Ihrig L, Ghosh S, Ofori-Acquah S, Hu X, Novelli EM. Hazra R, et al. Among authors: novelli em. Biomedicines. 2023 Feb 24;11(3):692. doi: 10.3390/biomedicines11030692. Biomedicines. 2023. PMID: 36979670 Free PMC article.

76

Astrocytic mitochondrial frataxin-A promising target for ischemic brain injury.

Hazra R, Novelli EM, Hu X. Hazra R, et al. Among authors: novelli em. CNS Neurosci Ther. 2023 Mar;29(3):783-788. doi: 10.1111/cns.14068. Epub 2022 Dec 22. CNS Neurosci Ther. 2023. PMID: 36550598 Free PMC article. Review.

77

Diagnostic Test Accuracy of Lung Ultrasound for Acute Chest Syndrome in Sickle Cell Disease: A Systematic Review and Meta-analysis.

Omar M, Jabir AR, Khan I, Novelli EM, Xu JZ. Omar M, et al. Among authors: novelli em. Chest. 2023 Jun;163(6):1506-1518. doi: 10.1016/j.chest.2022.11.042. Epub 2022 Dec 9. Chest. 2023. PMID: 36509124

78

Dimethyl Sulfoxide Induces Hemolysis and Pulmonary Hypertension.

Tofovic SP, Bilan VP, Rafikova O, Schneider F, Novelli EM, Jackson EK. Tofovic SP, et al. Among authors: novelli em. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2022 Dec 4;43(3):5-20. doi: 10.2478/prilozi-2022-0032. Print 2022 Nov 1. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2022. PMID: 36473034 Free article.

79

Ex vivo culture of cord blood CD34+ cells expands progenitor cell numbers, preserves engraftment capacity in nonobese diabetic/severe combined immunodeficient mice, and enhances retroviral transduction efficiency.

Novelli EM, Cheng L, Yang Y, Leung W, Ramírez M, Tanavde V, Enger C, Civin CI. Novelli EM, et al. Hum Gene Ther. 1999 Dec 10;10(18):2927-40. doi: 10.1089/10430349950016348. Hum Gene Ther. 1999. PMID: 10609654

80

Human hematopoietic stem/progenitor cells generate CD5+ B lymphoid cells in NOD/SCID mice.

Novelli EM, Ramírez M, Leung W, Civin CI. Novelli EM, et al. Stem Cells. 1999;17(5):242-52. doi: 10.1002/stem.170242. Stem Cells. 1999. PMID: 10527459

81

Biology of CD34+CD38- cells in lymphohematopoiesis.

Novelli EM, Ramirez M, Civin CI. Novelli EM, et al. Leuk Lymphoma. 1998 Oct;31(3-4):285-93. doi: 10.3109/10428199809059221. Leuk Lymphoma. 1998. PMID: 9869192 Review.

82

In vivo engraftment potential of clinical hematopoietic grafts.

Leung W, Ramírez M, Novelli EM, Civin CI. Leung W, et al. Among authors: novelli em. J Investig Med. 1998 Aug;46(6):303-11. J Investig Med. 1998. PMID: 9737093

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