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Page 1
Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli.
Yamazaki H, Nakamura M, Komatsu T, Ohyama K, Hatanaka N, Asahi S, Shimada N, Guengerich FP, Shimada T, Nakajima M, Yokoi T. Yamazaki H, et al. Among authors: ohyama k. Protein Expr Purif. 2002 Apr;24(3):329-37. doi: 10.1006/prep.2001.1578. Protein Expr Purif. 2002. PMID: 11922748
Minocycline-induced black bone disease of the skull.
Ohyama K, Nakae S, Uehara Y. Ohyama K, et al. Infection. 2024 Jun 10. doi: 10.1007/s15010-024-02317-7. Online ahead of print. Infection. 2024. PMID: 38856810 No abstract available.
Modeled Hepatic/Plasma Exposures of Fluvastatin Prescribed Alone in Subjects with Impaired Cytochrome P450 2C9*3 as One of Possible Determinant Factors Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database.
Adachi K, Ohyama K, Tanaka Y, Saito Y, Shimizu M, Yamazaki H. Adachi K, et al. Among authors: ohyama k. Biol Pharm Bull. 2024;47(3):635-640. doi: 10.1248/bpb.b24-00012. Biol Pharm Bull. 2024. PMID: 38494736 Free article.
Effect of rifampicin administration on CYP induction in a dermatomyositis patient with vasospastic angina attributable to nilmatrelvir/ritonavir-induced blood tacrolimus elevation: A case report.
Akamatsu H, Kohno Y, Hashizume J, Nakagawa H, Kodama Y, Kawano H, Maemura K, Ohyama K. Akamatsu H, et al. Among authors: ohyama k. J Infect Chemother. 2024 Feb 13:S1341-321X(24)00035-7. doi: 10.1016/j.jiac.2024.02.006. Online ahead of print. J Infect Chemother. 2024. PMID: 38360184
The impact of carbapenem shortage and stewardship countermeasures on antimicrobial practice at a tertiary care center.
Kouyama Y, Uehara Y, Takamatsu A, Suzuki R, Nishida R, Inuzuka K, Muramatsu E, Ohyama K, Doi Y, Yamada S, Honda H. Kouyama Y, et al. Among authors: ohyama k. Antimicrob Steward Healthc Epidemiol. 2023 Oct 19;3(1):e173. doi: 10.1017/ash.2023.460. eCollection 2023. Antimicrob Steward Healthc Epidemiol. 2023. PMID: 38028913 Free PMC article.
Pharmacokinetic Models Scaled-up from Humanized-liver Mouse Data Can Account for Drug Monitoring Results of Atomoxetine and Its 4-Hydroxylated and N-Demethylated Metabolites i n Pediatric Patients Genotyped for Cytochrome P450 2D6.
Shimizu M, Uehara S, Ohyama K, Nishimura H, Tanaka Y, Saito Y, Suemizu H, Yoshida S, Yamazaki H. Shimizu M, et al. Among authors: ohyama k. Drug Metab Dispos. 2023 Oct 25:DMD-AR-2023-001481. doi: 10.1124/dmd.123.001481. Online ahead of print. Drug Metab Dispos. 2023. PMID: 37879849 Free article.
Plasma and Hepatic Exposures of Celecoxib and Diclofenac Prescribed Alone in Patients with Cytochrome P450 2C9*3 Modeled after Virtual Oral Administrations and Likely Associated with Adverse Drug Events Reported in a Japanese Database.
Adachi K, Ohyama K, Tanaka Y, Nakano H, Sato T, Murayama N, Shimizu M, Saito Y, Yamazaki H. Adachi K, et al. Among authors: ohyama k. Biol Pharm Bull. 2023 Jun 1;46(6):856-863. doi: 10.1248/bpb.b23-00189. Epub 2023 Apr 15. Biol Pharm Bull. 2023. PMID: 37062721 Free article.
High hepatic and plasma exposures of atorvastatin in subjects harboring impaired cytochrome P450 3A4∗16 modeled after virtual administrations and possibly associated with statin intolerance found in the Japanese adverse drug event report database.
Adachi K, Ohyama K, Tanaka Y, Sato T, Murayama N, Shimizu M, Saito Y, Yamazaki H. Adachi K, et al. Among authors: ohyama k. Drug Metab Pharmacokinet. 2023 Apr;49:100486. doi: 10.1016/j.dmpk.2022.100486. Epub 2022 Dec 7. Drug Metab Pharmacokinet. 2023. PMID: 36746706
Immune complexome analysis of a rich variety of serum immune complexes identifies disease-characteristic immune complex antigens in systemic sclerosis.
Kutsuna YJ, Iwamoto N, Ichinose K, Aibara N, Nakashima K, Nakamura H, Koike Y, Murota H, Ueki Y, Miyamoto H, Hashizume J, Kodama Y, Nakashima M, Kawakami A, Ohyama K. Kutsuna YJ, et al. Among authors: ohyama k. J Autoimmun. 2023 Jan;134:102954. doi: 10.1016/j.jaut.2022.102954. Epub 2022 Nov 24. J Autoimmun. 2023. PMID: 36436353
Letrozole ameliorates liver fibrosis through the inhibition of the CTGF pathway and 17β-hydroxysteroid dehydrogenase 13 expression.
Sakai N, Kamimura K, Miyamoto H, Ko M, Nagoya T, Setsu T, Sakamaki A, Yokoo T, Kamimura H, Soki H, Tokunaga A, Inamine T, Nakashima M, Enomoto H, Kousaka K, Tachiki H, Ohyama K, Terai S. Sakai N, et al. Among authors: ohyama k. J Gastroenterol. 2023 Jan;58(1):53-68. doi: 10.1007/s00535-022-01929-w. Epub 2022 Oct 27. J Gastroenterol. 2023. PMID: 36301364
Immune complexome analysis of serum samples from non-small-cell lung cancer patients identifies predictive biomarkers for nivolumab therapy.
Aizawa R, Nakamura Y, Ikeda T, Aibara N, Kutsuna YJ, Kurosaki T, Aki K, Junya H, Nakagawa H, Sato K, Kodama Y, Nakashima MN, Nakashima M, Mukae H, Ohyama K. Aizawa R, et al. Among authors: ohyama k. Clin Chim Acta. 2022 Jul 1;532:84-88. doi: 10.1016/j.cca.2022.05.021. Epub 2022 Jun 3. Clin Chim Acta. 2022. PMID: 35667476
ANCA-Associated Vasculitic Neuropathies: A Review.
Koike H, Nishi R, Ohyama K, Morozumi S, Kawagashira Y, Furukawa S, Mouri N, Fukami Y, Iijima M, Sobue G, Katsuno M. Koike H, et al. Among authors: ohyama k. Neurol Ther. 2022 Mar;11(1):21-38. doi: 10.1007/s40120-021-00315-7. Epub 2022 Jan 19. Neurol Ther. 2022. PMID: 35044596 Free PMC article. Review.
Low-intensity pulsed ultrasound therapy suppresses coronary adventitial inflammatory changes and hyperconstricting responses after coronary stent implantation in pigs in vivo.
Watanabe T, Matsumoto Y, Nishimiya K, Shindo T, Amamizu H, Sugisawa J, Tsuchiya S, Sato K, Morosawa S, Ohyama K, Watanabe-Asaka T, Hayashi M, Kawai Y, Takahashi J, Yasuda S, Shimokawa H. Watanabe T, et al. Among authors: ohyama k. PLoS One. 2021 Sep 13;16(9):e0257175. doi: 10.1371/journal.pone.0257175. eCollection 2021. PLoS One. 2021. PMID: 34516572 Free PMC article.
Correction to: An analysis of the radiological factors associated with respiratory failure in COVID-19 pneumonia and the CT features among different age categories.
Fukuda A, Yanagawa N, Sekiya N, Ohyama K, Yomota M, Inui T, Fujiwara S, Kawai S, Fukushima K, Tanaka M, Kobayashi T, Yajima K, Imamura A. Fukuda A, et al. Among authors: ohyama k. Jpn J Radiol. 2021 Oct;39(10):1022. doi: 10.1007/s11604-021-01182-w. Jpn J Radiol. 2021. PMID: 34387815 Free PMC article. No abstract available.
Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells.
Kinoshita A, Ohyama K, Tanimura S, Matsuda K, Kishino T, Negishi Y, Asahina N, Shiraishi H, Hosoki K, Tomiwa K, Ishihara N, Mishima H, Mori R, Nakashima M, Saitoh S, Yoshiura KI. Kinoshita A, et al. Among authors: ohyama k. Development. 2021 Aug 15;148(16):dev188755. doi: 10.1242/dev.188755. Epub 2021 Aug 26. Development. 2021. PMID: 34338282
Analysis of extracellular vesicles as a potential index for monitoring differentiation of neural lineage cells from induced pluripotent stem cells.
Saito H, Kato M, Hirai K, Kiyama M, Ohyama K, Hanzawa H, Nakane A, Sekiya S, Yoshida K, Kishino A, Tsuchida A, Kimura T, Takahashi J, Takeda S. Saito H, et al. Among authors: ohyama k. J Biosci Bioeng. 2021 Oct;132(4):381-389. doi: 10.1016/j.jbiosc.2021.06.004. Epub 2021 Jul 18. J Biosci Bioeng. 2021. PMID: 34284947
The Expression of Transcription Factors in Fetal Lamb Kidney.
Nishiya Y, Kawaguchi K, Kudo K, Kawaguchi T, Obayashi J, Tanaka K, Ohyama K, Nagae H, Furuta S, Seki Y, Koike J, Pringle KC, Kitagawa H. Nishiya Y, et al. Among authors: ohyama k. J Dev Biol. 2021 Jun 19;9(2):22. doi: 10.3390/jdb9020022. J Dev Biol. 2021. PMID: 34205452 Free PMC article.
An analysis of the radiological factors associated with respiratory failure in COVID-19 pneumonia and the CT features among different age categories.
Fukuda A, Yanagawa N, Sekiya N, Ohyama K, Yomota M, Inui T, Fujiwara S, Kawai S, Fukushima K, Tanaka M, Kobayashi T, Yajima K, Imamura A. Fukuda A, et al. Among authors: ohyama k. Jpn J Radiol. 2021 Aug;39(8):783-790. doi: 10.1007/s11604-021-01118-4. Epub 2021 Apr 12. Jpn J Radiol. 2021. PMID: 33844123 Free PMC article.
Evaluation of four commercial severe acute respiratory coronavirus 2 antibody tests.
Ashizawa N, Takazono T, Ohyama K, Nagasaki Y, Okamoto M, Hirayama T, Takahashi K, Yamanashi H, Tashiro M, Hosogaya N, Tanaka T, Yamamoto K, Fukuda Y, Imamura Y, Kawanami T, Miyazaki T, Sawai T, Fukushima K, Yatera K, Yanagihara K, Izumikawa K, Mukae H. Ashizawa N, et al. Among authors: ohyama k. J Infect Chemother. 2021 Jul;27(7):1033-1038. doi: 10.1016/j.jiac.2021.03.008. Epub 2021 Mar 15. J Infect Chemother. 2021. PMID: 33781691 Free PMC article.
Prognostic Links Between OCT-Delineated Coronary Morphologies and Coronary Functional Abnormalities in Patients With INOCA.
Nishimiya K, Suda A, Fukui K, Hao K, Takahashi J, Matsumoto Y, Mitsuishi K, Watanabe T, Ohyama K, Sugisawa J, Tsuchiya S, Satoh K, Shindo T, Godo S, Kikuchi Y, Shiroto T, Yasuda S, Shimokawa H. Nishimiya K, et al. Among authors: ohyama k. JACC Cardiovasc Interv. 2021 Mar 22;14(6):606-618. doi: 10.1016/j.jcin.2020.12.025. JACC Cardiovasc Interv. 2021. PMID: 33736768 Free article.
Differences in post-operative complications after reconstruction for congenital biliary dilatation in a single institution-Roux-en-Y hepaticojejunostomy versus hepaticoduodenostomy.
Ohyama K, Furuta S, Shima H, Tuji S, Nagae H, Tanaka K, Obayashi J, Kawaguchi K, Kawaguchi T, Nishiya Y, Kudou K, Kawase K, Wakisaka M, Kitagawa H. Ohyama K, et al. Pediatr Surg Int. 2021 Feb;37(2):241-245. doi: 10.1007/s00383-020-04790-1. Epub 2021 Jan 22. Pediatr Surg Int. 2021. PMID: 33483835
Immune complexome analysis reveals the presence of immune complexes and identifies disease-specific immune complex antigens in saliva samples from patients with Sjögren's syndrome.
Yamane K, Nakamura H, Hamasaki M, Minei Y, Aibara N, Shimizu T, Kawakami A, Nakashima M, Kuroda N, Ohyama K. Yamane K, et al. Among authors: ohyama k. Clin Exp Immunol. 2021 May;204(2):212-220. doi: 10.1111/cei.13574. Epub 2021 Feb 22. Clin Exp Immunol. 2021. PMID: 33432580 Free PMC article.
The feasibility and safety in using acetaminophen with fentanyl for pain control after liver resection with regards to liver function: A prospective single-center pilot study in Japan.
Hidaka M, Ohyama K, Hara T, Soyama A, Adachi T, Kamada N, Nakashima M, Ichinomiya T, Hara T, Eguchi S. Hidaka M, et al. Among authors: ohyama k. J Hepatobiliary Pancreat Sci. 2021 Mar;28(3):297-303. doi: 10.1002/jhbp.892. Epub 2021 Feb 2. J Hepatobiliary Pancreat Sci. 2021. PMID: 33421327
Beneficial effects of exercise training on physical performance in patients with vasospastic angina.
Sugisawa J, Matsumoto Y, Takeuchi M, Suda A, Tsuchiya S, Ohyama K, Nishimiya K, Akizuki M, Sato K, Ohura S, Ota H, Ikeda S, Shindo T, Kikuchi Y, Hao K, Shiroto T, Takahashi J, Miyata S, Sakata Y, Takase K, Kohzuki M, Shimokawa H. Sugisawa J, et al. Among authors: ohyama k. Int J Cardiol. 2021 Apr 1;328:14-21. doi: 10.1016/j.ijcard.2020.12.003. Epub 2020 Dec 9. Int J Cardiol. 2021. PMID: 33309635 Clinical Trial.
Two cases of NMOSD with MRI findings mimicking CADASIL.
Maeda K, Dougu N, Ohyama K, Takahashi T, Mizuta I, Mizuno T, Kobayashi Y. Maeda K, et al. Among authors: ohyama k. Mult Scler Relat Disord. 2020 Nov;46:102532. doi: 10.1016/j.msard.2020.102532. Epub 2020 Sep 28. Mult Scler Relat Disord. 2020. PMID: 33032057
Prevalence and clinical features of hearing loss caused by EYA4 variants.
Shinagawa J, Moteki H, Nishio SY, Ohyama K, Otsuki K, Iwasaki S, Masuda S, Oshikawa C, Ohta Y, Arai Y, Takahashi M, Sakuma N, Abe S, Sakurai Y, Sakaguchi H, Ishino T, Uehara N, Usami SI. Shinagawa J, et al. Among authors: ohyama k. Sci Rep. 2020 Feb 27;10(1):3662. doi: 10.1038/s41598-020-60259-0. Sci Rep. 2020. PMID: 32107406 Free PMC article. Clinical Trial.
764 results