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2016 1
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2019 10
2020 10
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2022 8
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Page 1
Experimental pharmacology in precision medicine.
Urbaniak A, Thummel KE, Alade AN, Rettie AE, Prasad B, De Nicolò A, Martin JH, Sheppard DN, Jarvis MF. Urbaniak A, et al. Pharmacol Res Perspect. 2023 Dec;11(6):e01147. doi: 10.1002/prp2.1147. Pharmacol Res Perspect. 2023. PMID: 37885364 Free PMC article. No abstract available.
Obesity-Associated Dyslipidemia Is Moderated by Habitual Intake of Marine-Derived n-3 Polyunsaturated Fatty Acids in Yup'ik Alaska Native People: A Cross-Sectional Mediation-Moderation Analysis.
Boyer BB, Wiener HW, Hopkins SE, Purnell JQ, O'Brien DM, Aliwarga T, Pomeroy JJ, Aslan JE, Thummel KE, Tiwari HK. Boyer BB, et al. J Nutr. 2023 Jan;153(1):279-292. doi: 10.1016/j.tjnut.2022.10.009. Epub 2022 Dec 21. J Nutr. 2023. PMID: 36913463 Free PMC article.
PharmVar GeneFocus: CYP2C9.
Sangkuhl K, Claudio-Campos K, Cavallari LH, Agundez JAG, Whirl-Carrillo M, Duconge J, Del Tredici AL, Wadelius M, Rodrigues Botton M, Woodahl EL, Scott SA, Klein TE, Pratt VM, Daly AK, Gaedigk A. Sangkuhl K, et al. Clin Pharmacol Ther. 2021 Sep;110(3):662-676. doi: 10.1002/cpt.2333. Epub 2021 Jul 12. Clin Pharmacol Ther. 2021. PMID: 34109627 Free PMC article. Review.
Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function.
Fohner AE, Dalton R, Skagen K, Jackson K, Claw KG, Hopkins SE, Robinson R, Khan BA, Prasad B, Schuetz EG, Nickerson DA, Thornton TA, Dillard DA, Boyer BB, Thummel KE, Woodahl EL. Fohner AE, et al. Clin Transl Sci. 2021 Jul;14(4):1292-1302. doi: 10.1111/cts.12970. Epub 2021 Jan 27. Clin Transl Sci. 2021. PMID: 33503331 Free PMC article.
Transfer learning enables prediction of CYP2D6 haplotype function.
McInnes G, Dalton R, Sangkuhl K, Whirl-Carrillo M, Lee SB, Tsao PS, Gaedigk A, Altman RB, Woodahl EL. McInnes G, et al. PLoS Comput Biol. 2020 Nov 2;16(11):e1008399. doi: 10.1371/journal.pcbi.1008399. eCollection 2020 Nov. PLoS Comput Biol. 2020. PMID: 33137098 Free PMC article.
PharmVar GeneFocus: CYP2C19.
Botton MR, Whirl-Carrillo M, Del Tredici AL, Sangkuhl K, Cavallari LH, Agúndez JAG, Duconge J, Lee MTM, Woodahl EL, Claudio-Campos K, Daly AK, Klein TE, Pratt VM, Scott SA, Gaedigk A. Botton MR, et al. Clin Pharmacol Ther. 2021 Feb;109(2):352-366. doi: 10.1002/cpt.1973. Epub 2020 Jul 22. Clin Pharmacol Ther. 2021. PMID: 32602114 Free PMC article. Review.
Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6-Mediated Metabolic Activity.
Dalton R, Lee SB, Claw KG, Prasad B, Phillips BR, Shen DD, Wong LH, Fade M, McDonald MG, Dunham MJ, Fowler DM, Rettie AE, Schuetz E, Thornton TA, Nickerson DA, Gaedigk A, Thummel KE, Woodahl EL. Dalton R, et al. Clin Transl Sci. 2020 Jan;13(1):147-156. doi: 10.1111/cts.12695. Epub 2019 Oct 25. Clin Transl Sci. 2020. PMID: 31536170 Free PMC article.
Democratizing Precision Medicine Through Community Engagement.
Fohner AE, Volk KG, Woodahl EL. Fohner AE, et al. Clin Pharmacol Ther. 2019 Sep;106(3):488-490. doi: 10.1002/cpt.1508. Epub 2019 Jun 17. Clin Pharmacol Ther. 2019. PMID: 31206610 Free PMC article. No abstract available.
Applying Multiplex Assays to Understand Variation in Pharmacogenes.
Chiasson M, Dunham MJ, Rettie AE, Fowler DM. Chiasson M, et al. Clin Pharmacol Ther. 2019 Aug;106(2):290-294. doi: 10.1002/cpt.1468. Epub 2019 May 30. Clin Pharmacol Ther. 2019. PMID: 31145826 Free PMC article. No abstract available.
Responsible Research With Urban American Indians and Alaska Natives.
James RD, West KM, Claw KG, EchoHawk A, Dodge L, Dominguez A, Taualii M, Forquera R, Thummel K, Burke W. James RD, et al. Am J Public Health. 2018 Dec;108(12):1613-1616. doi: 10.2105/AJPH.2018.304708. Epub 2018 Oct 25. Am J Public Health. 2018. PMID: 30359103 Free PMC article. Review.
Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex.
Bhatt DK, Basit A, Zhang H, Gaedigk A, Lee SB, Claw KG, Mehrotra A, Chaudhry AS, Pearce RE, Gaedigk R, Broeckel U, Thornton TA, Nickerson DA, Schuetz EG, Amory JK, Leeder JS, Prasad B. Bhatt DK, et al. Drug Metab Dispos. 2018 Jun;46(6):888-896. doi: 10.1124/dmd.118.080952. Epub 2018 Mar 30. Drug Metab Dispos. 2018. PMID: 29602798 Free PMC article.
Cytochrome P450 Genetic Variation Associated with Tamoxifen Biotransformation in American Indian and Alaska Native People.
Khan BA, Robinson R, Fohner AE, Muzquiz LI, Schilling BD, Beans JA, Olnes MJ, Trawicki L, Frydenlund H, Laukes C, Beatty P, Phillips B, Nickerson D, Howlett K, Dillard DA, Thornton TA, Thummel KE, Woodahl EL. Khan BA, et al. Clin Transl Sci. 2018 May;11(3):312-321. doi: 10.1111/cts.12542. Epub 2018 Feb 13. Clin Transl Sci. 2018. PMID: 29436156 Free PMC article.
Implementing Precision Medicine: The Ethical Challenges.
Korngiebel DM, Thummel KE, Burke W. Korngiebel DM, et al. Trends Pharmacol Sci. 2017 Jan;38(1):8-14. doi: 10.1016/j.tips.2016.11.007. Epub 2016 Dec 7. Trends Pharmacol Sci. 2017. PMID: 27939182 Free PMC article. Review.