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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 3
2003 4
2004 2
2007 4
2008 5
2009 9
2010 9
2011 19
2012 31
2013 27
2014 31
2015 23
2016 15
2017 31
2018 25
2019 23
2020 17
2021 5
2022 1
2023 0
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248 results
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Page 1
Protein sequence design with a learned potential.
Anand N, Eguchi R, Mathews II, Perez CP, Derry A, Altman RB, Huang PS. Anand N, et al. Nat Commun. 2022 Feb 8;13(1):746. doi: 10.1038/s41467-022-28313-9. Nat Commun. 2022. PMID: 35136054 Free PMC article.
Verifying nomenclature of DNA variants in submitted manuscripts: Guidance for journals.
Higgins J, Dalgleish R, den Dunnen JT, Barsh G, Freeman PJ, Cooper DN, Cullinan S, Davies KE, Dorkins H, Gong L, Imoto I, Klein TE, Korf B, Misra A, Paalman MH, Ratzel S, Reichardt JKV, Rehm HL, Tokunaga K, Weck KE, Cutting GR. Higgins J, et al. Hum Mutat. 2021 Jan;42(1):3-7. doi: 10.1002/humu.24144. Epub 2020 Dec 10. Hum Mutat. 2021. PMID: 33252176 Free PMC article.
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA-B Genotypes and Phenytoin Dosing: 2020 Update.
Karnes JH, Rettie AE, Somogyi AA, Huddart R, Fohner AE, Formea CM, Ta Michael Lee M, Llerena A, Whirl-Carrillo M, Klein TE, Phillips EJ, Mintzer S, Gaedigk A, Caudle KE, Callaghan JT. Karnes JH, et al. Clin Pharmacol Ther. 2021 Feb;109(2):302-309. doi: 10.1002/cpt.2008. Epub 2020 Sep 6. Clin Pharmacol Ther. 2021. PMID: 32779747 Free PMC article. Review.
Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium.
Verma SS, Bergmeijer TO, Gong L, Reny JL, Lewis JP, Mitchell BD, Alexopoulos D, Aradi D, Altman RB, Bliden K, Bradford Y, Campo G, Chang K, Cleator JH, Déry JP, Dridi NP, Fernandez-Cadenas I, Fontana P, Gawaz M, Geisler T, Gensini GF, Giusti B, Gurbel PA, Hochholzer W, Holmvang L, Kim EY, Kim HS, Marcucci R, Montaner J, Backman JD, Pakyz RE, Roden DM, Schaeffeler E, Schwab M, Shin JG, Siller-Matula JM, Ten Berg JM, Trenk D, Valgimigli M, Wallace J, Wen MS, Kubo M, Lee MTM, Whaley R, Winter S, Klein TE, Shuldiner AR, Ritchie MD; ICPC Investigators. Verma SS, et al. Clin Pharmacol Ther. 2020 Nov;108(5):1067-1077. doi: 10.1002/cpt.1911. Epub 2020 Jul 9. Clin Pharmacol Ther. 2020. PMID: 32472697 Free PMC article.
PharmGKB summary: lamotrigine pathway, pharmacokinetics and pharmacodynamics.
Mitra-Ghosh T, Callisto SP, Lamba JK, Remmel RP, Birnbaum AK, Barbarino JM, Klein TE, Altman RB. Mitra-Ghosh T, et al. Pharmacogenet Genomics. 2020 Jun;30(4):81-90. doi: 10.1097/FPC.0000000000000397. Pharmacogenet Genomics. 2020. PMID: 32187155 Review. No abstract available.
PharmGKB summary: sertraline pathway, pharmacokinetics.
Huddart R, Hicks JK, Ramsey LB, Strawn JR, Smith DM, Bobonis Babilonia M, Altman RB, Klein TE. Huddart R, et al. Pharmacogenet Genomics. 2020 Feb;30(2):26-33. doi: 10.1097/FPC.0000000000000392. Pharmacogenet Genomics. 2020. PMID: 31851125 Free PMC article. No abstract available.
PGxMine: Text mining for curation of PharmGKB.
Lever J, Barbarino JM, Gong L, Huddart R, Sangkuhl K, Whaley R, Whirl-Carrillo M, Woon M, Klein TE, Altman RB. Lever J, et al. Pac Symp Biocomput. 2020;25:611-622. Pac Symp Biocomput. 2020. PMID: 31797632 Free PMC article.
PharmVar and the Landscape of Pharmacogenetic Resources.
Gaedigk A, Whirl-Carrillo M, Pratt VM, Miller NA, Klein TE. Gaedigk A, et al. Clin Pharmacol Ther. 2020 Jan;107(1):43-46. doi: 10.1002/cpt.1654. Epub 2019 Nov 23. Clin Pharmacol Ther. 2020. PMID: 31758698 Free PMC article. No abstract available.
A Call for Clear and Consistent Communications Regarding the Role of Pharmacogenetics in Antidepressant Pharmacotherapy.
Hicks JK, Bishop JR, Gammal RS, Sangkuhl K, Bousman CA, Leeder JS, Llerena A, Mueller DJ, Ramsey LB, Scott SA, Skaar TC, Caudle KE, Klein TE, Gaedigk A. Hicks JK, et al. Clin Pharmacol Ther. 2020 Jan;107(1):50-52. doi: 10.1002/cpt.1661. Epub 2019 Oct 30. Clin Pharmacol Ther. 2020. PMID: 31664715 Free PMC article. No abstract available.
Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group.
Caudle KE, Sangkuhl K, Whirl-Carrillo M, Swen JJ, Haidar CE, Klein TE, Gammal RS, Relling MV, Scott SA, Hertz DL, Guchelaar HJ, Gaedigk A. Caudle KE, et al. Clin Transl Sci. 2020 Jan;13(1):116-124. doi: 10.1111/cts.12692. Epub 2019 Oct 24. Clin Transl Sci. 2020. PMID: 31647186 Free PMC article.
PharmVar GeneFocus: CYP2D6.
Nofziger C, Turner AJ, Sangkuhl K, Whirl-Carrillo M, Agúndez JAG, Black JL, Dunnenberger HM, Ruano G, Kennedy MA, Phillips MS, Hachad H, Klein TE, Gaedigk A. Nofziger C, et al. Clin Pharmacol Ther. 2020 Jan;107(1):154-170. doi: 10.1002/cpt.1643. Epub 2019 Dec 9. Clin Pharmacol Ther. 2020. PMID: 31544239 Free PMC article. Review.
Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients.
Lewis JP, Backman JD, Reny JL, Bergmeijer TO, Mitchell BD, Ritchie MD, Déry JP, Pakyz RE, Gong L, Ryan K, Kim EY, Aradi D, Fernandez-Cadenas I, Lee MTM, Whaley RM, Montaner J, Gensini GF, Cleator JH, Chang K, Holmvang L, Hochholzer W, Roden DM, Winter S, Altman RB, Alexopoulos D, Kim HS, Gawaz M, Bliden KP, Valgimigli M, Marcucci R, Campo G, Schaeffeler E, Dridi NP, Wen MS, Shin JG, Fontana P, Giusti B, Geisler T, Kubo M, Trenk D, Siller-Matula JM, Ten Berg JM, Gurbel PA, Schwab M, Klein TE, Shuldiner AR; ICPC Investigators. Lewis JP, et al. Eur Heart J Cardiovasc Pharmacother. 2020 Jul 1;6(4):203-210. doi: 10.1093/ehjcvp/pvz045. Eur Heart J Cardiovasc Pharmacother. 2020. PMID: 31504375 Free PMC article.
Pharmacogenomics Clinical Annotation Tool (PharmCAT).
Sangkuhl K, Whirl-Carrillo M, Whaley RM, Woon M, Lavertu A, Altman RB, Carter L, Verma A, Ritchie MD, Klein TE. Sangkuhl K, et al. Clin Pharmacol Ther. 2020 Jan;107(1):203-210. doi: 10.1002/cpt.1568. Epub 2019 Sep 17. Clin Pharmacol Ther. 2020. PMID: 31306493 Free PMC article.
Predicting venous thromboembolism risk from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.
McInnes G, Daneshjou R, Katsonis P, Lichtarge O, Srinivasan R, Rana S, Radivojac P, Mooney SD, Pagel KA, Stamboulian M, Jiang Y, Capriotti E, Wang Y, Bromberg Y, Bovo S, Savojardo C, Martelli PL, Casadio R, Pal LR, Moult J, Brenner SE, Altman R. McInnes G, et al. Hum Mutat. 2019 Sep;40(9):1314-1320. doi: 10.1002/humu.23825. Epub 2019 Jun 24. Hum Mutat. 2019. PMID: 31140652 Free PMC article.
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz-Containing Antiretroviral Therapy.
Desta Z, Gammal RS, Gong L, Whirl-Carrillo M, Gaur AH, Sukasem C, Hockings J, Myers A, Swart M, Tyndale RF, Masimirembwa C, Iwuchukwu OF, Chirwa S, Lennox J, Gaedigk A, Klein TE, Haas DW. Desta Z, et al. Clin Pharmacol Ther. 2019 Oct;106(4):726-733. doi: 10.1002/cpt.1477. Epub 2019 Jul 5. Clin Pharmacol Ther. 2019. PMID: 31006110 Free PMC article.
Considerations for pharmacogenomic testing in a health system.
Gammal RS, Caudle KE, Klein TE, Relling MV. Gammal RS, et al. Genet Med. 2019 Aug;21(8):1886-1887. doi: 10.1038/s41436-018-0421-x. Epub 2019 Jan 9. Genet Med. 2019. PMID: 30631112 Free article. No abstract available.
The ACCOuNT Consortium: A Model for the Discovery, Translation, and Implementation of Precision Medicine in African Americans.
Friedman PN, Shaazuddin M, Gong L, Grossman RL, Harralson AF, Klein TE, Lee NH, Miller DC, Nutescu EA, O'Brien TJ, O'Donnell PH, O'Leary KJ, Tuck M, Meltzer DO, Perera MA. Friedman PN, et al. Clin Transl Sci. 2019 May;12(3):209-217. doi: 10.1111/cts.12608. Epub 2019 Feb 12. Clin Transl Sci. 2019. PMID: 30592548 Free PMC article. Review.
The Evolution of PharmVar.
Gaedigk A, Sangkuhl K, Whirl-Carrillo M, Twist GP, Klein TE, Miller NA; PharmVar Steering Committee. Gaedigk A, et al. Clin Pharmacol Ther. 2019 Jan;105(1):29-32. doi: 10.1002/cpt.1275. Epub 2018 Dec 7. Clin Pharmacol Ther. 2019. PMID: 30536702 Free PMC article. Review. No abstract available.
Pharmacogene Variation Consortium Gene Introduction: NUDT15.
Yang JJ, Whirl-Carrillo M, Scott SA, Turner AJ, Schwab M, Tanaka Y, Suarez-Kurtz G, Schaeffeler E, Klein TE, Miller NA, Gaedigk A. Yang JJ, et al. Clin Pharmacol Ther. 2019 May;105(5):1091-1094. doi: 10.1002/cpt.1268. Epub 2018 Dec 4. Clin Pharmacol Ther. 2019. PMID: 30515762 Free PMC article. No abstract available.
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for the Use of Potent Volatile Anesthetic Agents and Succinylcholine in the Context of RYR1 or CACNA1S Genotypes.
Gonsalves SG, Dirksen RT, Sangkuhl K, Pulk R, Alvarellos M, Vo T, Hikino K, Roden D, Klein TE, Poler SM, Patel S, Caudle KE, Gordon R, Brandom B, Biesecker LG. Gonsalves SG, et al. Clin Pharmacol Ther. 2019 Jun;105(6):1338-1344. doi: 10.1002/cpt.1319. Epub 2019 Jan 24. Clin Pharmacol Ther. 2019. PMID: 30499100 Free PMC article. Review.
The Case for Pharmacogenetics-Guided Prescribing of Codeine in Children.
Gammal RS, Caudle KE, Quinn CT, Wang WC, Gaedigk A, Prows CA, Haidar CE, Taylor AK, Klein TE, Sangkuhl K, Hankins JS, Crews KR. Gammal RS, et al. Clin Pharmacol Ther. 2019 Jun;105(6):1300-1302. doi: 10.1002/cpt.1260. Epub 2018 Nov 22. Clin Pharmacol Ther. 2019. PMID: 30467830 Free PMC article. Review. No abstract available.
Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update.
Relling MV, Schwab M, Whirl-Carrillo M, Suarez-Kurtz G, Pui CH, Stein CM, Moyer AM, Evans WE, Klein TE, Antillon-Klussmann FG, Caudle KE, Kato M, Yeoh AEJ, Schmiegelow K, Yang JJ. Relling MV, et al. Clin Pharmacol Ther. 2019 May;105(5):1095-1105. doi: 10.1002/cpt.1304. Epub 2019 Jan 20. Clin Pharmacol Ther. 2019. PMID: 30447069 Free PMC article.
Essential Characteristics of Pharmacogenomics Study Publications.
Thorn CF, Whirl-Carrillo M, Hachad H, Johnson JA, McDonagh EM, Ratain MJ, Relling MV, Scott SA, Altman RB, Klein TE. Thorn CF, et al. Clin Pharmacol Ther. 2019 Jan;105(1):86-91. doi: 10.1002/cpt.1279. Clin Pharmacol Ther. 2019. PMID: 30406943 Free PMC article. Review.
PharmGKB summary: oxycodone pathway, pharmacokinetics.
Huddart R, Clarke M, Altman RB, Klein TE. Huddart R, et al. Pharmacogenet Genomics. 2018 Oct;28(10):230-237. doi: 10.1097/FPC.0000000000000351. Pharmacogenet Genomics. 2018. PMID: 30222708 Free PMC article. No abstract available.
PharmGKB summary: clozapine pathway, pharmacokinetics.
Thorn CF, Müller DJ, Altman RB, Klein TE. Thorn CF, et al. Pharmacogenet Genomics. 2018 Sep;28(9):214-222. doi: 10.1097/FPC.0000000000000347. Pharmacogenet Genomics. 2018. PMID: 30134346 Free PMC article. No abstract available.
Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC).
Bergmeijer TO, Reny JL, Pakyz RE, Gong L, Lewis JP, Kim EY, Aradi D, Fernandez-Cadenas I, Horenstein RB, Lee MTM, Whaley RM, Montaner J, Gensini GF, Cleator JH, Chang K, Holmvang L, Hochholzer W, Roden DM, Winter S, Altman RB, Alexopoulos D, Kim HS, Déry JP, Gawaz M, Bliden K, Valgimigli M, Marcucci R, Campo G, Schaeffeler E, Dridi NP, Wen MS, Shin JG, Simon T, Fontana P, Giusti B, Geisler T, Kubo M, Trenk D, Siller-Matula JM, Ten Berg JM, Gurbel PA, Hulot JS, Mitchell BD, Schwab M, Ritchie MD, Klein TE, Shuldiner AR; ICPC Investigators. Bergmeijer TO, et al. Am Heart J. 2018 Apr;198:152-159. doi: 10.1016/j.ahj.2017.12.010. Epub 2017 Dec 17. Am Heart J. 2018. PMID: 29653637 Free PMC article. Review.
Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder.
Amare AT, Schubert KO, Tekola-Ayele F, Hsu YH, Sangkuhl K, Jenkins G, Whaley RM, Barman P, Batzler A, Altman RB, Arolt V, Brockmöller J, Chen CH, Domschke K, Hall-Flavin DK, Hong CJ, Illi A, Ji Y, Kampman O, Kinoshita T, Leinonen E, Liou YJ, Mushiroda T, Nonen S, Skime MK, Wang L, Kato M, Liu YL, Praphanphoj V, Stingl JC, Bobo WV, Tsai SJ, Kubo M, Klein TE, Weinshilboum RM, Biernacka JM, Baune BT. Amare AT, et al. Front Psychiatry. 2018 Mar 6;9:65. doi: 10.3389/fpsyt.2018.00065. eCollection 2018. Front Psychiatry. 2018. PMID: 29559929 Free PMC article.
PharmGKB summary: clobazam pathway, pharmacokinetics.
Huddart R, Leeder JS, Altman RB, Klein TE. Huddart R, et al. Pharmacogenet Genomics. 2018 Apr;28(4):110-115. doi: 10.1097/FPC.0000000000000327. Pharmacogenet Genomics. 2018. PMID: 29517622 Free PMC article. No abstract available.
PharmGKB: A worldwide resource for pharmacogenomic information.
Barbarino JM, Whirl-Carrillo M, Altman RB, Klein TE. Barbarino JM, et al. Wiley Interdiscip Rev Syst Biol Med. 2018 Jul;10(4):e1417. doi: 10.1002/wsbm.1417. Epub 2018 Feb 23. Wiley Interdiscip Rev Syst Biol Med. 2018. PMID: 29474005 Free PMC article. Review.
Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects.
Volpi S, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Jacob HJ, Kasapi M, McLeod HL, Roden DM, Williams MS, Green ED, Rodriguez LL, Aronson S, Cavallari LH, Denny JC, Dressler LG, Johnson JA, Klein TE, Leeder JS, Piquette-Miller M, Perera M, Rasmussen-Torvik LJ, Rehm HL, Ritchie MD, Skaar TC, Wagle N, Weinshilboum R, Weitzel KW, Wildin R, Wilson J, Manolio TA, Relling MV. Volpi S, et al. Clin Pharmacol Ther. 2018 May;103(5):778-786. doi: 10.1002/cpt.1048. Epub 2018 Mar 30. Clin Pharmacol Ther. 2018. PMID: 29460415 Free PMC article. Review.
Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update.
Phillips EJ, Sukasem C, Whirl-Carrillo M, Müller DJ, Dunnenberger HM, Chantratita W, Goldspiel B, Chen YT, Carleton BC, George AL Jr, Mushiroda T, Klein T, Gammal RS, Pirmohamed M. Phillips EJ, et al. Clin Pharmacol Ther. 2018 Apr;103(4):574-581. doi: 10.1002/cpt.1004. Epub 2018 Feb 2. Clin Pharmacol Ther. 2018. PMID: 29392710 Free PMC article.
PharmCAT: A Pharmacogenomics Clinical Annotation Tool.
Klein TE, Ritchie MD. Klein TE, et al. Clin Pharmacol Ther. 2018 Jul;104(1):19-22. doi: 10.1002/cpt.928. Epub 2017 Dec 1. Clin Pharmacol Ther. 2018. PMID: 29194583 Free PMC article.
PharmGKB summary: very important pharmacogene information for ABCG2.
Fohner AE, Brackman DJ, Giacomini KM, Altman RB, Klein TE. Fohner AE, et al. Pharmacogenet Genomics. 2017 Nov;27(11):420-427. doi: 10.1097/FPC.0000000000000305. Pharmacogenet Genomics. 2017. PMID: 28858993 Free PMC article. Review. No abstract available.
PharmGKB summary: pazopanib pathway, pharmacokinetics.
Thorn CF, Sharma MR, Altman RB, Klein TE. Thorn CF, et al. Pharmacogenet Genomics. 2017 Aug;27(8):307-312. doi: 10.1097/FPC.0000000000000292. Pharmacogenet Genomics. 2017. PMID: 28678138 Free PMC article. Review. No abstract available.
Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.
Daneshjou R, Wang Y, Bromberg Y, Bovo S, Martelli PL, Babbi G, Lena PD, Casadio R, Edwards M, Gifford D, Jones DT, Sundaram L, Bhat RR, Li X, Pal LR, Kundu K, Yin Y, Moult J, Jiang Y, Pejaver V, Pagel KA, Li B, Mooney SD, Radivojac P, Shah S, Carraro M, Gasparini A, Leonardi E, Giollo M, Ferrari C, Tosatto SCE, Bachar E, Azaria JR, Ofran Y, Unger R, Niroula A, Vihinen M, Chang B, Wang MH, Franke A, Petersen BS, Pirooznia M, Zandi P, McCombie R, Potash JB, Altman RB, Klein TE, Hoskins RA, Repo S, Brenner SE, Morgan AA. Daneshjou R, et al. Hum Mutat. 2017 Sep;38(9):1182-1192. doi: 10.1002/humu.23280. Epub 2017 Jul 7. Hum Mutat. 2017. PMID: 28634997 Free PMC article.
Pharmacogenomics-Based Point-of-Care Clinical Decision Support Significantly Alters Drug Prescribing.
O'Donnell PH, Wadhwa N, Danahey K, Borden BA, Lee SM, Hall JP, Klammer C, Hussain S, Siegler M, Sorrentino MJ, Davis AM, Sacro YA, Nanda R, Polonsky TS, Koyner JL, Burnet DL, Lipstreuer K, Rubin DT, Mulcahy C, Strek ME, Harper W, Cifu AS, Polite B, Patrick-Miller L, Yeo KT, Leung E, Volchenboum SL, Altman RB, Olopade OI, Stadler WM, Meltzer DO, Ratain MJ. O'Donnell PH, et al. Clin Pharmacol Ther. 2017 Nov;102(5):859-869. doi: 10.1002/cpt.709. Epub 2017 Jun 15. Clin Pharmacol Ther. 2017. PMID: 28398598 Free PMC article.
PharmGKB summary: sorafenib pathways.
Gong L, Giacomini MM, Giacomini C, Maitland ML, Altman RB, Klein TE. Gong L, et al. Pharmacogenet Genomics. 2017 Jun;27(6):240-246. doi: 10.1097/FPC.0000000000000279. Pharmacogenet Genomics. 2017. PMID: 28362716 Free PMC article. Review. No abstract available.
PharmGKB summary: voriconazole pathway, pharmacokinetics.
Barbarino JM, Owusu Obeng A, Klein TE, Altman RB. Barbarino JM, et al. Pharmacogenet Genomics. 2017 May;27(5):201-209. doi: 10.1097/FPC.0000000000000276. Pharmacogenet Genomics. 2017. PMID: 28277330 Free PMC article. No abstract available.
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update.
Johnson JA, Caudle KE, Gong L, Whirl-Carrillo M, Stein CM, Scott SA, Lee MT, Gage BF, Kimmel SE, Perera MA, Anderson JL, Pirmohamed M, Klein TE, Limdi NA, Cavallari LH, Wadelius M. Johnson JA, et al. Clin Pharmacol Ther. 2017 Sep;102(3):397-404. doi: 10.1002/cpt.668. Epub 2017 Apr 4. Clin Pharmacol Ther. 2017. PMID: 28198005 Free PMC article.
The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and Metrics of Pharmacogenetic Implementations Across Diverse Healthcare Systems.
Luzum JA, Pakyz RE, Elsey AR, Haidar CE, Peterson JF, Whirl-Carrillo M, Handelman SK, Palmer K, Pulley JM, Beller M, Schildcrout JS, Field JR, Weitzel KW, Cooper-DeHoff RM, Cavallari LH, O'Donnell PH, Altman RB, Pereira N, Ratain MJ, Roden DM, Embi PJ, Sadee W, Klein TE, Johnson JA, Relling MV, Wang L, Weinshilboum RM, Shuldiner AR, Freimuth RR; Pharmacogenomics Research Network Translational Pharmacogenetics Program. Luzum JA, et al. Clin Pharmacol Ther. 2017 Sep;102(3):502-510. doi: 10.1002/cpt.630. Epub 2017 Jun 9. Clin Pharmacol Ther. 2017. PMID: 28090649 Free PMC article.
Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update.
Hicks JK, Sangkuhl K, Swen JJ, Ellingrod VL, Müller DJ, Shimoda K, Bishop JR, Kharasch ED, Skaar TC, Gaedigk A, Dunnenberger HM, Klein TE, Caudle KE, Stingl JC. Hicks JK, et al. Clin Pharmacol Ther. 2017 Jul;102(1):37-44. doi: 10.1002/cpt.597. Epub 2017 Feb 13. Clin Pharmacol Ther. 2017. PMID: 27997040 Free PMC article.
Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics.
Kalia SS, Adelman K, Bale SJ, Chung WK, Eng C, Evans JP, Herman GE, Hufnagel SB, Klein TE, Korf BR, McKelvey KD, Ormond KE, Richards CS, Vlangos CN, Watson M, Martin CL, Miller DT. Kalia SS, et al. Genet Med. 2017 Feb;19(2):249-255. doi: 10.1038/gim.2016.190. Epub 2016 Nov 17. Genet Med. 2017. PMID: 27854360 Free article.
PharmGKB summary: very important pharmacogene information for MT-RNR1.
Barbarino JM, McGregor TL, Altman RB, Klein TE. Barbarino JM, et al. Pharmacogenet Genomics. 2016 Dec;26(12):558-567. doi: 10.1097/FPC.0000000000000247. Pharmacogenet Genomics. 2016. PMID: 27654872 Free PMC article. Review. No abstract available.
Population-specific single-nucleotide polymorphism confers increased risk of venous thromboembolism in African Americans.
Daneshjou R, Cavallari LH, Weeke PE, Karczewski KJ, Drozda K, Perera MA, Johnson JA, Klein TE, Bustamante CD, Roden DM, Shaffer C, Denny JC, Zehnder JL, Altman RB. Daneshjou R, et al. Mol Genet Genomic Med. 2016 Jun 21;4(5):513-20. doi: 10.1002/mgg3.226. eCollection 2016 Sep. Mol Genet Genomic Med. 2016. PMID: 27652279 Free PMC article.
PharmGKB summary: ivacaftor pathway, pharmacokinetics/pharmacodynamics.
Fohner AE, McDonagh EM, Clancy JP, Whirl Carrillo M, Altman RB, Klein TE. Fohner AE, et al. Pharmacogenet Genomics. 2017 Jan;27(1):39-42. doi: 10.1097/FPC.0000000000000246. Pharmacogenet Genomics. 2017. PMID: 27636560 Free PMC article. No abstract available.
PharmGKB summary: isoniazid pathway, pharmacokinetics.
Klein DJ, Boukouvala S, McDonagh EM, Shuldiner SR, Laurieri N, Thorn CF, Altman RB, Klein TE. Klein DJ, et al. Pharmacogenet Genomics. 2016 Sep;26(9):436-44. doi: 10.1097/FPC.0000000000000232. Pharmacogenet Genomics. 2016. PMID: 27232112 Free PMC article. No abstract available.
Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity.
Burridge PW, Li YF, Matsa E, Wu H, Ong SG, Sharma A, Holmström A, Chang AC, Coronado MJ, Ebert AD, Knowles JW, Telli ML, Witteles RM, Blau HM, Bernstein D, Altman RB, Wu JC. Burridge PW, et al. Nat Med. 2016 May;22(5):547-56. doi: 10.1038/nm.4087. Epub 2016 Apr 18. Nat Med. 2016. PMID: 27089514 Free PMC article.
PharmGKB summary: very important pharmacogene information for RYR1.
Alvarellos ML, Krauss RM, Wilke RA, Altman RB, Klein TE. Alvarellos ML, et al. Pharmacogenet Genomics. 2016 Mar;26(3):138-44. doi: 10.1097/FPC.0000000000000198. Pharmacogenet Genomics. 2016. PMID: 26709912 Free PMC article. Review. No abstract available.
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.
Kalman LV, Agúndez J, Appell ML, Black JL, Bell GC, Boukouvala S, Bruckner C, Bruford E, Caudle K, Coulthard SA, Daly AK, Del Tredici A, den Dunnen JT, Drozda K, Everts RE, Flockhart D, Freimuth RR, Gaedigk A, Hachad H, Hartshorne T, Ingelman-Sundberg M, Klein TE, Lauschke VM, Maglott DR, McLeod HL, McMillin GA, Meyer UA, Müller DJ, Nickerson DA, Oetting WS, Pacanowski M, Pratt VM, Relling MV, Roberts A, Rubinstein WS, Sangkuhl K, Schwab M, Scott SA, Sim SC, Thirumaran RK, Toji LH, Tyndale RF, van Schaik R, Whirl-Carrillo M, Yeo K, Zanger UM. Kalman LV, et al. Clin Pharmacol Ther. 2016 Feb;99(2):172-85. doi: 10.1002/cpt.280. Epub 2015 Nov 20. Clin Pharmacol Ther. 2016. PMID: 26479518 Free PMC article. Review.
Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data.
Dewey FE, Grove ME, Priest JR, Waggott D, Batra P, Miller CL, Wheeler M, Zia A, Pan C, Karzcewski KJ, Miyake C, Whirl-Carrillo M, Klein TE, Datta S, Altman RB, Snyder M, Quertermous T, Ashley EA. Dewey FE, et al. PLoS Genet. 2015 Oct 8;11(10):e1005496. doi: 10.1371/journal.pgen.1005496. eCollection 2015 Oct. PLoS Genet. 2015. PMID: 26448358 Free PMC article.
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing.
Gammal RS, Court MH, Haidar CE, Iwuchukwu OF, Gaur AH, Alvarellos M, Guillemette C, Lennox JL, Whirl-Carrillo M, Brummel SS, Ratain MJ, Klein TE, Schackman BR, Caudle KE, Haas DW; Clinical Pharmacogenetics Implementation Consortium. Gammal RS, et al. Clin Pharmacol Ther. 2016 Apr;99(4):363-9. doi: 10.1002/cpt.269. Epub 2015 Nov 9. Clin Pharmacol Ther. 2016. PMID: 26417955 Free PMC article. Review.
Genome-wide association study of warfarin maintenance dose in a Brazilian sample.
Parra EJ, Botton MR, Perini JA, Krithika S, Bourgeois S, Johnson TA, Tsunoda T, Pirmohamed M, Wadelius M, Limdi NA, Cavallari LH, Burmester JK, Rettie AE, Klein TE, Johnson JA, Hutz MH, Suarez-Kurtz G. Parra EJ, et al. Pharmacogenomics. 2015;16(11):1253-63. doi: 10.2217/PGS.15.73. Epub 2015 Aug 12. Pharmacogenomics. 2015. PMID: 26265036 Free PMC article.
PharmGKB summary: peginterferon-α pathway.
Shuldiner SR, Gong L, Muir AJ, Altman RB, Klein TE. Shuldiner SR, et al. Pharmacogenet Genomics. 2015 Sep;25(9):465-74. doi: 10.1097/FPC.0000000000000158. Pharmacogenet Genomics. 2015. PMID: 26111151 Free PMC article. No abstract available.
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