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Page 1
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.
Tsai J, Lee JT, Wang W, Zhang J, Cho H, Mamo S, Bremer R, Gillette S, Kong J, Haass NK, Sproesser K, Li L, Smalley KS, Fong D, Zhu YL, Marimuthu A, Nguyen H, Lam B, Liu J, Cheung I, Rice J, Suzuki Y, Luu C, Settachatgul C, Shellooe R, Cantwell J, Kim SH, Schlessinger J, Zhang KY, West BL, Powell B, Habets G, Zhang C, Ibrahim PN, Hirth P, Artis DR, Herlyn M, Bollag G. Tsai J, et al. Among authors: suzuki y. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3041-6. doi: 10.1073/pnas.0711741105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287029 Free PMC article.
Structural basis for ligand reception by anaplastic lymphoma kinase.
Li T, Stayrook SE, Tsutsui Y, Zhang J, Wang Y, Li H, Proffitt A, Krimmer SG, Ahmed M, Belliveau O, Walker IX, Mudumbi KC, Suzuki Y, Lax I, Alvarado D, Lemmon MA, Schlessinger J, Klein DE. Li T, et al. Among authors: suzuki y. Nature. 2021 Dec;600(7887):148-152. doi: 10.1038/s41586-021-04141-7. Epub 2021 Nov 24. Nature. 2021. PMID: 34819665 Free PMC article.
Structural basis for the activity of drugs that inhibit phosphodiesterases.
Card GL, England BP, Suzuki Y, Fong D, Powell B, Lee B, Luu C, Tabrizizad M, Gillette S, Ibrahim PN, Artis DR, Bollag G, Milburn MV, Kim SH, Schlessinger J, Zhang KY. Card GL, et al. Among authors: suzuki y. Structure. 2004 Dec;12(12):2233-47. doi: 10.1016/j.str.2004.10.004. Structure. 2004. PMID: 15576036 Free article.
A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases.
Zhang KY, Card GL, Suzuki Y, Artis DR, Fong D, Gillette S, Hsieh D, Neiman J, West BL, Zhang C, Milburn MV, Kim SH, Schlessinger J, Bollag G. Zhang KY, et al. Among authors: suzuki y. Mol Cell. 2004 Jul 23;15(2):279-86. doi: 10.1016/j.molcel.2004.07.005. Mol Cell. 2004. PMID: 15260978 Free article.
B-type natriuretic peptide level reduction and its predictors following sodium-glucose cotransporter 2 inhibitor treatment in patients with diabetic kidney disease: a Japan Chronic Kidney Disease Database Extension analysis.
Nagahiro T, Konishi M, Kanaoka T, Wakui H, Yano Y, Nagasu H, Kishi S, Nangaku M, Hirakawa Y, Nakagawa N, Wada J, Tsuruya K, Nakano T, Maruyama S, Wada T, Yamagata K, Narita I, Yanagita M, Terada Y, Araki SI, Emoto M, Okada H, Isaka Y, Suzuki Y, Yokoo T, Kataoka H, Kanda E, Kashihara N, Tamura K; J-CKD-DB Collaborators. Nagahiro T, et al. Among authors: suzuki y. Diabetes Res Clin Pract. 2026 Jun 15:113377. doi: 10.1016/j.diabres.2026.113377. Online ahead of print. Diabetes Res Clin Pract. 2026. PMID: 42297213
Clinical Implications of Polyploid Giant Cancer Cells in Solid Tumors: Biology, Diagnosis, and Therapeutic Considerations.
Imaoka H, Ikeda M, Wakabayashi M, Umemoto K, Satake T, Sunakawa Y, Ueno H, Hara K, Nagashima F, Kataoka S, Hisano T, Suzuki Y, Asagi A, Shioji K, Oshima K, Tsuji K, Ohkawa K, Miki I, Kawamoto Y, Yamashita T, Ueno M, Kawakami Y, Nagano H, Okuyama H, Naganuma A, Suzuki R, Furuse J; Japan Oncology Network in Hepatobiliary and Pancreas. Imaoka H, et al. Among authors: suzuki y. Cancers (Basel). 2026 Jun 1;18(11):1818. doi: 10.3390/cancers18111818. Cancers (Basel). 2026. PMID: 42279400 Free PMC article. Review.
Humoral Response to COVID-19 Vaccines and Infection During Sibeprenlimab Treatment of IgA Nephropathy: Data from the ENVISION Trial.
McCafferty K, Barratt J, Suzuki Y, Liew A, Rizk DV, Chacko B, Kooienga L, Lafayette R, Wong MG, Pasetti MF, Shriver MC, Follman K, Moc Willeford C, Sahay M, Honig G, Andrews L, Olinski LE, Mathur M, Oldach D. McCafferty K, et al. Among authors: suzuki y. Clin J Am Soc Nephrol. 2026 Jun 11. doi: 10.2215/CJN.0000001089. Online ahead of print. Clin J Am Soc Nephrol. 2026. PMID: 42275148
Association of Weight Loss With Improvement in Metabolic Status Among People Eligible for the Specific Health Guidance Program.
Nishikawa M, Suzuki Y, Ko T, Kaneko H, Okada A, Takeda N, Morita H, Fujiu K, Azegami T, Hayashi K, Kitaoka K, Miura K, Furui Y, Node K, Yasunaga H, Nangaku M, Takeda N. Nishikawa M, et al. Among authors: suzuki y. Circ Rep. 2026 Apr 14;8(6):909-914. doi: 10.1253/circrep.CR-25-0266. eCollection 2026 Jun 10. Circ Rep. 2026. PMID: 42273303 Free PMC article.
Utilization of meat juice from market-purchased pork for serological surveillance of mosquito-borne arboviruses.
Kuwata R, Thu LNA, Phuong DTM, Takeishi M, Inoue Y, Ohta N, Flores Lino VI, Ogawa H, Watanabe S, Shimoda H, Suzuki Y, Hang PT, Amano M, Abe H, Higa Y, Isawa H, Maeda K, Phung LD, Hasebe F, Kasai S. Kuwata R, et al. Among authors: suzuki y. J Vet Med Sci. 2026 Jun 11. doi: 10.1292/jvms.26-0242. Online ahead of print. J Vet Med Sci. 2026. PMID: 42270413 Free article.
[EOSINOPHIL-ASSOCIATED DISEASES: A PATHOBIOLOGY-BASED, CROSS-ORGAN PERSPECTIVE].
Ueki S, Yamada Y, Miyata J, Kamide Y, Suzuki Y, Morita H, Otsuka K, Yoshikawa M, Oguma T, Takabayashi T, Matsuda A, Ebihara N, Oishi K, Nakagome K, Ishimura N, Asano K. Ueki S, et al. Among authors: suzuki y. Arerugi. 2026;75(3):214-221. doi: 10.15036/arerugi.75.214. Arerugi. 2026. PMID: 42270344 Japanese. No abstract available.
NKG2D-based CAR-T cells for synovial sarcoma: A preclinical proof-of-concept study.
Miyazaki T, Murayama Y, Oike N, Baba M, Kasahara Y, Shin C, Kubo N, Ariizumi T, Suzuki Y, Mihara K, Ling Y, Okuda S, Saitoh A, Imamura M, Ogose A, Kawashima H, Imai C. Miyazaki T, et al. Among authors: suzuki y. Biomed Pharmacother. 2026 Jun 8;200:119637. doi: 10.1016/j.biopha.2026.119637. Online ahead of print. Biomed Pharmacother. 2026. PMID: 42259140 Free article.
Finerenone in Patients With Chronic Kidney Disease Due to Glomerular Diseases: A Randomized Clinical Trial.
Neuen BL, Perkovic V, Agarwal R, Cherney DZI, Lam CSP, Wanner C, Tuttle KR, Sarafidis P, Barratt J, Burgner A, Chen X, Chew-Wong A, Dobronravov VA, Floege J, McCafferty K, Nangaku M, Packham D, Papachristou E, Pergola PE, Speeckaert MM, Subbiah A, Tang SCW, Tang S, Yeo SC, Jongs N, Smeijer JD, Berger M, Brinker M, Dayoub R, Elliott J, Li N, Mueller K, Rethemeier N, Finkelsztein MY, Heerspink HJL; FIND-CKD Investigators. Neuen BL, et al. JAMA. 2026 Jun 5:e269923. doi: 10.1001/jama.2026.9923. Online ahead of print. JAMA. 2026. PMID: 42246414
Atrasentan in patients with IgA nephropathy (ALIGN): final 2·5-year results from a randomised, double-blind, placebo-controlled, phase 3 trial.
Heerspink HJL, Jardine MJ, Kohan DE, Lafayette R, Levin A, Liew A, Zhang H, Noronha IL, Mastroianni-Kirsztajn G, Chow S, Choi DE, Lv J, Trimarchi H, Fu P, Guenther S, Yang S, Liu J, Rahalkar S, Lodha A, Dahlke M, Kollins D, Barratt J; ALIGN study group. Heerspink HJL, et al. Lancet. 2026 Jun 13;407(10546):2387-2401. doi: 10.1016/S0140-6736(26)00960-8. Epub 2026 Jun 4. Lancet. 2026. PMID: 42242268 Clinical Trial.
A novel reagent for the screening of Immunoglobulin A-deficient blood donors.
Watanabe-Okochi N, Sato A, Okuyama A, Tomiyoshi G, Suzuki Y, Watanabe Y, Anazawa M, Shimoyamada T, Takahashi D, Onodera T, Uchikawa M, Miyata S. Watanabe-Okochi N, et al. Among authors: suzuki y. Vox Sang. 2026 Jun 2. doi: 10.1111/vox.70305. Online ahead of print. Vox Sang. 2026. PMID: 42227027
FGF21 suppresses hepatocellular carcinoma by driving competitive cell-cell interactions.
Ogawa M, Fujisawa T, Takenaka S, Yano M, Kuroda M, Taniguchi D, Wang Z, Hiratsuka T, Kanai A, Suzuki Y, Sato S, Miyagi Y, Takano A, Daigo Y, Nita A, Moroishi T, Naguro I, Ichijo H. Ogawa M, et al. Among authors: suzuki y. Cell Rep. 2026 May 29;45(6):117410. doi: 10.1016/j.celrep.2026.117410. Online ahead of print. Cell Rep. 2026. PMID: 42217188 Free article.
Author Correction: Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant.
Suzuki R, Yamasoba D, Kimura I, Wang L, Kishimoto M, Ito J, Morioka Y, Nao N, Nasser H, Uriu K, Kosugi Y, Tsuda M, Orba Y, Sasaki M, Shimizu R, Kawabata R, Yoshimatsu K, Asakura H, Nagashima M, Sadamasu K, Yoshimura K; Genotype to Phenotype Japan (G2P-Japan) Consortium; Sawa H, Ikeda T, Irie T, Matsuno K, Tanaka S, Fukuhara T, Sato K. Suzuki R, et al. Nature. 2026 May 29. doi: 10.1038/s41586-026-10665-7. Online ahead of print. Nature. 2026. PMID: 42215749 No abstract available.
Giants within: a new class of microbial mobile elements.
Kiguchi Y, Suzuki Y. Kiguchi Y, et al. Among authors: suzuki y. Trends Genet. 2026 May 30:S0168-9525(26)00113-7. doi: 10.1016/j.tig.2026.05.004. Online ahead of print. Trends Genet. 2026. PMID: 42215376 Review.
Gender-related differences in characteristics and treatment response between attention-deficit/hyperactivity disorder Japanese children with and without autism spectrum disorder: a single-center retrospective study.
Kawasaki Y, Suzuki Y, Miyazaki K, Suzuki N, Hoshina M, Ise Y, Suzuki Y, Morita H, Go H. Kawasaki Y, et al. Among authors: suzuki y, suzuki n. Brain Dev. 2026 May 29;48(4):104548. doi: 10.1016/j.braindev.2026.104548. Online ahead of print. Brain Dev. 2026. PMID: 42214913
Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection.
Hou J, Lim SG, Buti M, Yuen MF, Gane E, Lampertico P, Terrault N, Nguyen H, Yim HJ, Xie Q, Lin J, Qiu Y, Jeng WJ, Heo J, Peng CY, Chen CH, Chuang WL, Xie Y, Hlebowicz M, Idriz N, Mehta R, Agarwal K, Gomes da Silva MM, Franca A, Cernat R, Leerapun A, Coffin CS, Gadano A, Andreone P, Fujiyama S, Sevastianos V, Suzuki Y, Ratziu V, Riachi G, Stocker H, Lim TH, Asselah T, Tanaka Y, Holmes J, Liang X, Cremer J, Lukić T, Plein H, Quinn G, Tao Y, Paff M, Theodore D, Elston R; B-Well Study Group. Hou J, et al. Among authors: suzuki y. N Engl J Med. 2026 May 28. doi: 10.1056/NEJMoa2515131. Online ahead of print. N Engl J Med. 2026. PMID: 42206582
Feasibility of Peroral Pancreatoscopy Using the 9-Fr eyeMAX for Surgical Planning in Main-Duct and Mixed-Type Intraductal Papillary Mucinous Neoplasms.
Miwa H, Irie K, Fujiyoshi T, Sakai N, Soma R, Shibasaki K, Ishino Y, Tsunoda S, Matsuoka Y, Hamaguchi T, Endo K, Oishi R, Suzuki Y, Tsuchiya H, Funaoka A, Suzuki Y, Komiyama S, Goda Y, Morimoto M, Maeda S. Miwa H, et al. Among authors: suzuki y. Diagnostics (Basel). 2026 May 9;16(10):1443. doi: 10.3390/diagnostics16101443. Diagnostics (Basel). 2026. PMID: 42196809 Free PMC article.
Efficacy, Safety, and Cost-Effectiveness of Reduced versus Full Initial Doses of Androgen Receptor Signaling Inhibitors in Non-Metastatic Castration-Resistant Prostate Cancer: A Multicenter Retrospective Study.
Asanuma H, Fujita N, Kato S, Kawashima Y, Shinohara M, Tabata R, Yoneyama F, Tanaka R, Oishi T, Miura H, Togashi K, Okita K, Horiguchi H, Tanaka T, Noro D, Suzuki Y, Sato S, Ohyama C, Hatakeyama S. Asanuma H, et al. Among authors: suzuki y. Prostate. 2026 May 26. doi: 10.1002/pros.70203. Online ahead of print. Prostate. 2026. PMID: 42190045
Response to Third-Line Erlotinib in Peritoneal Carcinomatosis from Initially EGFR Mutation-Negative Lung Adenocarcinoma, Followed by the Retrospective Confirmation of EGFR Mutation-Positivity by Immunohistochemistry.
Fujimoto Y, Inao T, Ikeuchi M, Shimizu A, Ohbayashi C, Mitsui A, Imao M, Namba K, Kume S, Monden K, Otsuka K, Suzuki Y. Fujimoto Y, et al. Among authors: suzuki y. Intern Med. 2026 May 23. doi: 10.2169/internalmedicine.7216-26. Online ahead of print. Intern Med. 2026. PMID: 42178260 Free article.
Apoptosis Inhibitor of Macrophage and Acute Inflammation in IgA Nephropathy.
Kato R, Suzuki H, Aoki R, Koizumi A, Fukao Y, Nakayama M, Nihei Y, Kano T, Makita Y, Muto M, Yasuda K, Arai S, Miyazaki T, Suzuki Y. Kato R, et al. Among authors: suzuki h, suzuki y. Kidney360. 2026 May 22. doi: 10.34067/KID.0000001202. Online ahead of print. Kidney360. 2026. PMID: 42172081 Free article.
Association of Care Time with Physical Activity in Patients with Stroke.
Kobayashi S, Kimura Y, Kubo H, Yoshida K, Ishigaki T, Shimizu N, Kai T, Suzuki Y, Tanaka S, Takeuchi M, Yamamoto S, Moronaga K, Yoshimura T, Kanai M. Kobayashi S, et al. Among authors: suzuki y. Rehabil Nurs. 2026 May 22. doi: 10.1097/RNJ.0000000000000552. Online ahead of print. Rehabil Nurs. 2026. PMID: 42170806
Atezolizumab for relapsed/refractory extranodal NK/T-cell lymphoma: the phase II NCCH1903/ATTACK trial.
Makita S, Koya J, Suzuki Y, Nishikori M, Fukuhara N, Miyagi Maeshima A, Hirkawa A, Ito Y, Kogure Y, Chiba K, Okada A, Shiraishi Y, Kawashima S, Nagasaka Y, Fujimoto A, Nagai H, Takeuchi K, Kataoka K, Izutsu K. Makita S, et al. Among authors: suzuki y. Blood Adv. 2026 May 20:bloodadvances.2026019929. doi: 10.1182/bloodadvances.2026019929. Online ahead of print. Blood Adv. 2026. PMID: 42160759
Exhausted CD4+T cells are associated with CCL4-driven immunosuppressive macrophage accumulation in enzootic bovine leukosis.
Nakamura H, Okagawa T, Hamaïdia M, Tiyamanee W, Ikehata M, Hirose M, Inoue M, Willems L, Maezono K, Thammahakin P, Kobayashi S, Kato Y, Suzuki Y, Maekawa N, Murata S, Ohashi K, Konnai S. Nakamura H, et al. Among authors: suzuki y. Front Immunol. 2026 May 4;17:1808815. doi: 10.3389/fimmu.2026.1808815. eCollection 2026. Front Immunol. 2026. PMID: 42158858 Free PMC article.
Minimal change disease in a patient with type 1 diabetes and Crohn's disease managed with advanced hybrid closed-loop insulin therapy during corticosteroid treatment.
Sato A, Harai N, Fumoto R, Suzuki Y, Uchida T, Matsumura K, Yokoyama Y, Sekine A, Matsui A, Kono K, Takazawa Y, Ohashi K, Nagasawa K, Mori Y. Sato A, et al. Among authors: suzuki y. Diabetol Int. 2026 May 15;17(3):52. doi: 10.1007/s13340-026-00909-2. eCollection 2026 Jul. Diabetol Int. 2026. PMID: 42147068
Comparative Efficacy of Transfusion Strategies in Women and Men With Myocardial Infarction and Anemia: Prespecified Secondary Findings From the MINT Trial.
Abbott JD, Benatar JR, Ballantyne CM, Jacobs AK, Goldsweig AM, Fergusson DA, Hebert BM, Bertolet M, Simon T, Steg PG, Goodman SG, White HD, Carson JL, Brooks MM; MINT Investigators. Abbott JD, et al. Circulation. 2026 May 18. doi: 10.1161/CIRCULATIONAHA.125.078320. Online ahead of print. Circulation. 2026. PMID: 42145087
Comparison of anthracycline plus platinum versus other platinum-based regimens as first-line chemotherapy for untreated thymoma: A retrospective cohort study (NEJ023B).
Saito G, Ko R, Shiko Y, Takahashi K, Nagai Y, Ebina-Shibuya R, Isobe K, Nishiyama K, Wakui H, Takashima Y, Sonehara K, Shimamura S, Kaira K, Nakahara Y, Ashinuma H, Nagashima H, Suzuki Y, Chubachi K, Sugisaka J, Watanabe K, Tozuka T, Ro S, Hisakane K, Sasaki T, Sakashita H, Hanada S, Maemondo M, Kobayashi K, Shukuya T. Saito G, et al. Among authors: suzuki y. Lung Cancer. 2026 Jul;217:109456. doi: 10.1016/j.lungcan.2026.109456. Epub 2026 May 12. Lung Cancer. 2026. PMID: 42143520
In Response to "Is low lean body mass a risk factor for hypertension?".
Azegami T, Kaneko H, Okada A, Suzuki Y, Aoyama K, Fujiu K, Takeda N, Morita H, Yokoo T, Nangaku M, Node K, Takeda N, Yasunaga H, Hayashi K. Azegami T, et al. Among authors: suzuki y. Hypertens Res. 2026 May 13. doi: 10.1038/s41440-026-02670-0. Online ahead of print. Hypertens Res. 2026. PMID: 42129574 No abstract available.
Evaluating postoperative pneumatic lymphatic drainage following lymphaticovenous anastomosis for secondary lower extremity lymphoedema in Japan (LVA-PLD trial): protocol for a multicentre randomised controlled trial.
Akita S, Nishioka R, Tokunaga H, Ando N, Yamada K, Yamaji Y, Saito G, Takahashi K, Hattori Y, Hayashi A, Ando Y, Nuri T, Onishi F, Kadota H, Shinaoka A, Takanari K, Suzuki Y, Yasunaga Y, Hanaoka H, Mitsukawa N. Akita S, et al. Among authors: suzuki y. BMJ Open. 2026 May 13;16(5):e118108. doi: 10.1136/bmjopen-2026-118108. BMJ Open. 2026. PMID: 42128517 Free PMC article.
Nationwide surveillance of antibacterial susceptibility patterns of bacterial pathogens isolated from otorhinolaryngological infectious diseases in Japan.
Yano H, Suzuki K, Kamide Y, Hotomi M, Hayashi T, Sato J, Takahashi S, Matsumoto T, Yanagisawa H, Nakamura S, Takata M, Yamamoto K, Furuta Y, Nagano E, Katori Y, Kakuta R, Watanabe K, Kakehata S, Suzuki Y, Chikamatsu K, Kuwabara M, Fujimaki Y, Sugita R, Okada H, Ikeda K, Matsumoto F, Furuki S, Sugano S, Baba H, Maruyama Y, Matsubara S, Yokota A, Fujisawa T, Kishimoto A, Miyamoto N, Iwasaki S, Kabaya K, Sakai M, Hidaka H, Iwai H, Maeda T, Hayashi Y, Sakamoto T, Horibe Y, Kunimoto M, Sugahara K, Hiyoshi M, Shimizu T, Sawada S, Hirano T, Watanabe T, Kumai Y, Kitaoka K, Uchizomo A. Yano H, et al. Among authors: suzuki k, suzuki y. J Infect Chemother. 2026 May 12;32(8):102995. doi: 10.1016/j.jiac.2026.102995. Online ahead of print. J Infect Chemother. 2026. PMID: 42128293
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