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Outcomes following radiotherapy for atypical teratoid/rhabdoid tumor in combination with surgery and intensive chemotherapy: A report from Children's Oncology Group study ACNS0333.
Aridgides P, Mahajan A, Merchant TE, Krailo M, Buxton A, Deck J, Strother D, Huang A, Biegel JA, Ho B, Mazewski C, Lewis V, Pollack IF, Leary SES, Fouladi M, Reddy AT. Aridgides P, et al. Neurooncol Pediatr. 2026 Jan;2(1):wuaf015. doi: 10.1093/neuped/wuaf015. Epub 2025 Nov 25. Neurooncol Pediatr. 2026. PMID: 42181026 Free PMC article.
Atezolizumab plus FOLFOX for Stage III Mismatch Repair-Deficient Colon Cancer.
Sinicrope FA, Ou FS, Arnold D, Peters WR, Behrens RJ, Lieu CH, Matin K, Cohen DJ, Potter SL, Nixon AB, Kottschade LA, Kathol E, Frankel WL, Shergill A, Hsu D, Reinacher-Schick A, Mehan P, Gold PJ, Khalil MF, Zemla T, Gatten C, O'Reilly EM, Meyerhardt JA. Sinicrope FA, et al. N Engl J Med. 2026 Mar 26;394(12):1155-1166. doi: 10.1056/NEJMoa2507874. N Engl J Med. 2026. PMID: 41880612 Free PMC article. Clinical Trial.
Genome-wide association study meta-analysis identifies susceptibility loci informing Ewing sarcoma etiology and potential mechanisms of risk.
Hubbard AK, Neyret-Kahn H, Müller-Nurasiyd M, Löw D, Strauch K, Lee OW, Raduski AR, Yang T, Zhou W, Stratton EW, Jay O, Grossetête S, Song AJ, Dutta D, Hutchinson AA, Hicks BD, Manning M, Liu J, Boyce C, Hartmann W, Dirksen U, Kulozik AE, Metzler M, Krumbholz M, Teumer A, Völzke H, Völker U, Schiffman JD, Khan J, Hudson MM, Ness KK, Wang Z, Janeway KA, Lupo PJ, Spector LG, Huang WY, Moore SC, Chanock SJ, Grünewald TGP, Delattre O, Machiela MJ. Hubbard AK, et al. medRxiv [Preprint]. 2026 Feb 9:2026.02.06.26345779. doi: 10.64898/2026.02.06.26345779. medRxiv. 2026. PMID: 41728338 Free PMC article. Preprint.
Incorporating Intensity Modulated Total Body Irradiation (IMRT-TBI) Into Future Cooperative Group Clinical Trials: An NRG Hematologic Malignancies Working Group-Led Report From the National Clinical Trials Network.
Kovalchuk N, Simiele EA, LaRiviere M, Hiniker SM, Soike M, Han C, Wong J, Dandapani S, Kumar K, Parsons D, Teruel JR, Gerber NK, Guo B, Cherian S, Lim TY, Latifi K, Figura NB, Shrestha DK, Grecula J, Sim AJ, Parikh RR, Lo AC, Smith K, Plastaras JP, Xiao Y, Hoppe BS, Milgrom SA. Kovalchuk N, et al. Int J Radiat Oncol Biol Phys. 2026 Jul 1;125(3):714-736. doi: 10.1016/j.ijrobp.2026.02.201. Epub 2026 Feb 17. Int J Radiat Oncol Biol Phys. 2026. PMID: 41713515 Free PMC article.
Evaluating the use of hierarchical composite endpoints in pediatric cancer supportive care clinical trials: Illustrative examples from two multi-center phase-III randomized clinical trials.
Collier WH, Zobeck M, Esbenshade AJ, Dvorak CC, Sung L, Freyer D, Alexander S, Orgel E, Ullrich NJ, Prudowsky Z, Fisher B, Elgarten CW. Collier WH, et al. medRxiv [Preprint]. 2026 Jan 23:2026.01.20.26344064. doi: 10.64898/2026.01.20.26344064. medRxiv. 2026. PMID: 41659071 Free PMC article. Preprint.
Subsequent Neoplasm Risk After Modern Mediastinal Radiation Therapy for Pediatric Hodgkin Lymphoma: Insights From a Multi-Institutional Children's Oncology Group Trial.
Milgrom SA, Paganetti H, Dama H, Renfro L, Wu Y, Meyer I, Jeeva M, Parsons SK, Punnett A, Charpentier AM, Lo AC, Vega RM, Keller FG, Kelly KM, Hoppe BS, Castellino SM, Hodgson D. Milgrom SA, et al. Int J Radiat Oncol Biol Phys. 2026 Jul 15;125(4):1121-1129. doi: 10.1016/j.ijrobp.2026.01.026. Epub 2026 Feb 6. Int J Radiat Oncol Biol Phys. 2026. PMID: 41655816 Free PMC article.
Pediatric acute myeloid leukemia tumor composition predicts patient outcomes at diagnosis and reveals mechanisms of resistance to chemotherapy.
NajafPanah MJ, Stevens AM, Krueger MJ, Rochette M, Sandhu S, Kim L, Addanki S, Cooper J, Chiu HS, Epps J, Somvanshi S, Zorman B, Martinez MR, Rapsomaniki M, Unger S, Becher B, Yi JS, Man TK, Redell ML, Sumazin P. NajafPanah MJ, et al. Res Sq [Preprint]. 2026 Jan 23:rs.3.rs-4669225. doi: 10.21203/rs.3.rs-4669225/v1. Res Sq. 2026. PMID: 41646346 Free PMC article. Preprint.
Uncovering the genomic complexity of PAX5 intragenic tandem multiplication via long-read and short-read sequencing.
Liu Y, Ju B, Dong L, Loyd M, Brady SW, Ries R, Feng Y, Mulder H, Plyler E, Deardorff C, McBride A, Jones T, Eckert A, Kolekar P, Fan L, Li H, Briviba M, Zhao H, Bennett D, Neale G, Chang TC, Chen W, Pounds S, Wu G, Mullighan C, Geeleher P, Ji L, Yang JJ, Meshinchi S, Brown PA, Carroll WL, Zhang J, Loh ML, Easton J, Ma X. Liu Y, et al. Blood. 2026 Mar 26;147(13):1498-1502. doi: 10.1182/blood.2025031289. Blood. 2026. PMID: 41587071 Free PMC article.
Diminished Quality of Life Despite Reduced Treatment in Children With B-Lymphoblastic Leukemia: Children's Oncology Group AALL0932.
Balsamo LM, Kairalla JA, Hibbitts E, Rodwin RL, Devidas M, Dreyzin A, Winick NJ, Carroll WL, Hunger SP, Raetz EA, Schore RJ, Loh ML, Ness KK, Angiolillo AL, Kadan-Lottick NS. Balsamo LM, et al. Pediatr Blood Cancer. 2026 Mar;73(3):e70029. doi: 10.1002/1545-5017.70029. Epub 2026 Jan 5. Pediatr Blood Cancer. 2026. PMID: 41486974 Free PMC article. Clinical Trial.
Enhancing Radiation Therapy Quality Assurance in Lymphoma: A Rigorous Real-Time Central Review Process in AHOD2131.
Lo AC, Milgrom SA, Vega RM, Hodgson D, Chapman H, Kessel S, Cho SY, Schoder H, Mhlanga J, Pandit-Taskar N, Lai H, Gowdy C, Qi J, Abu-Ata N, Hu B, Seelisch J, Keller F, Castellino SM, LaCasce A, Grover N, Evens A, DuVall A, Allen P, Renfro LA, Wu Y, Kelly KM, Hoppe BS. Lo AC, et al. Int J Radiat Oncol Biol Phys. 2026 Jul 1;125(3):737-742. doi: 10.1016/j.ijrobp.2025.12.011. Epub 2025 Dec 24. Int J Radiat Oncol Biol Phys. 2026. PMID: 41453454 Free PMC article.
Factors Associated With Rare Pediatric Cancer Trial Enrollment: A Report From the Children's Oncology Group Rare Tumors Committee.
Englum BR, Piao J, Younis L, Baertschiger RM, Chen KS, Christison-Lagay E, Dholaria H, Gartrell R, Hicks MJ, Kamihara J, Mitchell SG, Orjuela-Grimm M, Pashankar F, Potter SL, Aldrink JH, Rosenblum J, Sargen MR, Schultz KAP, Seynnaeve BKN, Wedekind M, Laetsch TW. Englum BR, et al. Pediatr Blood Cancer. 2026 Feb;73(2):e32164. doi: 10.1002/pbc.32164. Epub 2025 Dec 26. Pediatr Blood Cancer. 2026. PMID: 41451685 Free PMC article.
Philadelphia chromosome-positive acute lymphoblastic leukaemia in children and adolescents: A changing treatment landscape and a methodological challenge.
Balduzzi A, Valsecchi MG, Tran TH, Zuna J, Leoni V, Cario G, Fazio G, Gandemer V, Tasian SK, van der Sluis IM, Peccatori N, Parasole R, Monterisi S, Loh ML, Devidas M, Hunger SP, Kairalla JA, De Lorenzo P, Silverman LB, Biondi A. Balduzzi A, et al. Br J Haematol. 2026 Mar;208(3):1127-1132. doi: 10.1111/bjh.70288. Epub 2025 Dec 25. Br J Haematol. 2026. PMID: 41448829 Free PMC article. No abstract available.
Phase 3 randomized trial of postirradiation chemotherapy in patients with newly diagnosed ependymoma: A report from the Children's Oncology Group.
Smith AA, Onar-Thomas A, Lensing S, Dalton J, Bennett J, Tatevossian RG, Bertrand K, Lindsay H, Tabori U, Owens-Pickle E, Blackburn PR, Handler MH, Chambwe N, El Khoury L, Lau C, Kunin-Batson A, Sands S, Wu S, Zhou T, Chang A, Merchant TE, Leary S, Fouladi M, Gajjar A, Pollack IF, Foreman NK, Ellison DW. Smith AA, et al. Neuro Oncol. 2026 May 1;28(5):1286-1297. doi: 10.1093/neuonc/noaf285. Neuro Oncol. 2026. PMID: 41423745 Free article. Clinical Trial.
Multimodality Artificial Intelligence for Involved-Site Radiation Therapy: Clinical Target Volume Delineation in High-Risk Pediatric Hodgkin Lymphoma.
Tie X, Milgrom SA, Lo AC, Charpentier AM, LaRiviere MJ, Maqbool D, Cho SY, Kelly KM, Hodgson D, Castellino SM, Hoppe BS, Bradshaw TJ. Tie X, et al. Int J Radiat Oncol Biol Phys. 2026 Jul 1;125(3):919-930. doi: 10.1016/j.ijrobp.2025.12.005. Epub 2025 Dec 13. Int J Radiat Oncol Biol Phys. 2026. PMID: 41391612 Free PMC article.
Analysis of error profiles of indels and structural variants in deep-sequencing data.
Shao Y, Tran Q, Feng Y, Kolekar P, Liu Y, Liang Z, Fan L, McBride A, Jones T, Cameron A, Mulder H, Ji L, Huang BJ, Klco JM, Meshinchi S, Zhang J, Carroll WL, Loh ML, Easton J, Brown PA, Ma X. Shao Y, et al. Cell Genom. 2026 Feb 11;6(2):101082. doi: 10.1016/j.xgen.2025.101082. Epub 2025 Dec 2. Cell Genom. 2026. PMID: 41338220 Free PMC article.
Factors Associated With Primary Site Local Therapy in Patients With Nonmetastatic Ewing Sarcoma Treated With Interval-Compressed Chemotherapy: A Report From the Children's Oncology Group.
Ahmed SK, Binitie O, Krailo M, Indelicato DJ, Callan AK, DelRocco N, Buxton A, Chuba P, Christ A, Randall RL, Nadel H, Pawel B, Reed DR, Gorlick RG, DuBois SG, Janeway KA, Leavey PJ, Mascarenhas L, Laack NNI. Ahmed SK, et al. Int J Radiat Oncol Biol Phys. 2026 Jun 1;125(2):521-529. doi: 10.1016/j.ijrobp.2025.11.010. Epub 2025 Nov 22. Int J Radiat Oncol Biol Phys. 2026. PMID: 41285272 Free PMC article. Clinical Trial.
Hypothesis-generating analysis of mutational signatures in childhood B-cell acute lymphoblastic leukemia in relation to socio-demographic, genetic, and environmental factors: A report from the Children's Oncology Group.
Clark CJ, Lu Z, Anderson N, Li Y, Park JE, Love M, Marcotte E, de Smith AJ, Spector LG. Clark CJ, et al. medRxiv [Preprint]. 2025 Oct 9:2025.10.02.25336752. doi: 10.1101/2025.10.02.25336752. medRxiv. 2025. PMID: 41282801 Free PMC article. Preprint.
Characterization of Chemoresistant Cell Populations Improves Risk Stratification and Therapy Prediction in Pediatric AML.
NajafPanah MJ, Stevens AM, Krueger MJ, Rochette M, Sandhu S, Kim L, Chiu HS, Epps J, Somvanshi S, Zorman B, Martinez MR, Rapsomaniki M, Unger S, Becher B, Yi JS, Man TK, Redell MS, Sumazin P. NajafPanah MJ, et al. bioRxiv [Preprint]. 2025 Oct 20:2025.09.25.678688. doi: 10.1101/2025.09.25.678688. bioRxiv. 2025. PMID: 41256415 Free PMC article. Preprint.
Impact of Pulmonary Tumor Burden in Favorable Histology Wilms Tumor Outcomes: A Report From the Children's Oncology Group Study AREN0533.
Dix DB, Khanna G, Renfro LA, Tfirn IC, Smith EA, Artunduaga M, Eklund MJ, Sandberg JK, Parsons LN, Kalapurakal JA, Ehrlich PF, Aldrink JH, Glick RD, Benedetti DJ, Fernandez CV, Dome JS, Mullen EA, Geller JI; COG Renal Tumor Committee. Dix DB, et al. J Clin Oncol. 2025 Dec 20;43(36):3822-3832. doi: 10.1200/JCO-25-00532. Epub 2025 Nov 12. J Clin Oncol. 2025. PMID: 41223336 Free PMC article.
Molecular Characterization Informs Prognosis in Patients With Localized Ewing Sarcoma: A Report From the Children's Oncology Group.
Gillani R, Shulman DS, DelRocco NJ, Klega K, Han R, Krailo MD, Slack JC, Tanhaemami M, Ward A, Bainer V, Ricker C, Sparks J, Bailey KM, Reed DR, DuBois SG, Leavey P, Mascarenhas L, Grohar PJ, Church AJ, Crompton BD, Janeway KA. Gillani R, et al. J Clin Oncol. 2025 Dec 10;43(35):3750-3759. doi: 10.1200/JCO-25-00157. Epub 2025 Nov 3. J Clin Oncol. 2025. PMID: 41183255 Free PMC article.
Germline Cancer Predisposition Results From the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial.
Scollon S, Plon SE, Joffe S, Biegel JA, Kulkarni S, Miles G, Patton DR, Coffey B, Winter CL, Tsongalis GJ, Routbort MJ, Ramirez NC, Saguilig L, Piao J, Alonzo TA, Berg SL, Fox E, Weigel B, Hawkins DS, Abrams JS, Mooney M, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DW; NCI-COG Pediatric MATCH Germline Reporting Committee. Scollon S, et al. JCO Precis Oncol. 2025 Oct;9:e2500742. doi: 10.1200/PO-25-00742. Epub 2025 Oct 30. JCO Precis Oncol. 2025. PMID: 41166674 Free PMC article.
A Phase 2 Trial of RANKL Antibody, Denosumab, in Two Cohorts of Patients with Recurrent/Refractory Osteosarcoma, a Report from the Children's Oncology Group.
Janeway KA, Chou AJ, Buxton A, Reid J, Isakoff MS, Kopp L, Hingorani P, Lee JL, Doski J, Daldrup-Link H, Hall L, Randall RL, Reed DR, Dubois SG, Krailo M, Grier H, Gorlick R. Janeway KA, et al. Clin Cancer Res. 2026 Jan 6;32(1):36-44. doi: 10.1158/1078-0432.CCR-24-2885. Clin Cancer Res. 2026. PMID: 41159913 Free PMC article. Clinical Trial.
Sequential Combination of Unfavorable Histology, Followed by Clinical Stage M, Defines High-Risk Neuroblastoma: A Report from the Children's Oncology Group.
Hazard FK, Toland AMS, Tan SY, Chiu B, Ikegaki N, Naranjo A, Cohn SL, London WB, Gastier-Foster JM, Ramirez NC, Reshmi SC, Wagner E, Nuchtern J, Asgharzadeh S, Marachelian A, Maris JM, Bagatell R, Park JR, Irwin MS, Hogarty MD, Shimada H. Hazard FK, et al. Clin Cancer Res. 2026 Jan 6;32(1):127-134. doi: 10.1158/1078-0432.CCR-24-4369. Clin Cancer Res. 2026. PMID: 41143597 Free PMC article.
Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci.
Im C, Raduski AR, Mills LJ, Bhattarai KR, Mobley RJ, Barnett KR, Lu Z, Liao K, Anderson N, Johnson RA, Langer E, Hooten AJ, Seif AE, Bernt KM, Tsang M, Mamou BA, Gil-de-Gómez L, Wolfson JA, Friedman DN, Shukla N, Klesse LJ, Marcotte EL, Ji L, Dang A, Luo M, Zhong Y, Langie J, Chiang CWK, de Smith A, Wiemels JL, DeWan A, Ma X, Metayer C, Wang Z, Nelson HH, Pankratz N, Yang T, Basu S, Turcotte LM, Yang JJ, Savic D, Scheurer ME, Spector LG. Im C, et al. Nat Commun. 2025 Oct 22;16(1):8974. doi: 10.1038/s41467-025-64337-7. Nat Commun. 2025. PMID: 41125582 Free PMC article.
Molecular risk markers define risk of relapse in myeloid leukemia of Down syndrome beyond measurable residual disease.
Berman JN, Verma A, Viola S, Alonzo TA, Wang YC, Brodersen LE, Loken M, Beckman A, Hirsch B, Raimondi S, Chisholm KM, Ma X, Ries R, Meshinchi S, Gamis A, Schore R, Taub JW, Kolb EA, Cooper T, Hitzler J. Berman JN, et al. Blood Adv. 2026 Mar 10;10(5):1576-1586. doi: 10.1182/bloodadvances.2025017837. Blood Adv. 2026. PMID: 41124669 Free PMC article.
A multicenter observational cohort study in survivors of Down Syndrome-associated acute leukemia (ALTE22C1): a report from the Children's Oncology Group.
Gramatges MM, Sanclemente LN, Hall L, Taylor OA, Nuño MM, Bhatia S, Chow EJ, Getz KD, Hitzler JK, Li AM, McCloskey K, Nathan PC, O'Brien MM, Patel S, Verma A, Yarbrough AR, Richard MA, Rosser TC, Jacola LM, Lupo PJ, Rabin KR. Gramatges MM, et al. BMC Cancer. 2025 Oct 20;25(1):1611. doi: 10.1186/s12885-025-14898-z. BMC Cancer. 2025. PMID: 41116168 Free PMC article.
Late effects after high-risk neuroblastoma (LEAHRN): a multicentre, cross-sectional cohort study from the Children's Oncology Group.
Henderson TO, Bardwell JK, Kao PC, Nathan PC, Landier W, Mostoufi-Moab S, Brinkman TM, Schulte F, Park JR, Armenian SH, Naranjo A, Subramaniam M, Marachellian A, Diskin SJ, London WB, Diller LR. Henderson TO, et al. Lancet Child Adolesc Health. 2025 Nov;9(11):776-786. doi: 10.1016/S2352-4642(25)00241-X. Epub 2025 Sep 25. Lancet Child Adolesc Health. 2025. PMID: 41016399 Free PMC article.
SMARCAL1 is a new osteosarcoma predisposition gene.
Rafati M, Guenther LM, Egolf LE, Gianferante M, Kim J, Wang K, Zhu B, Spector LG, Anderson N, Janeway KA, Barkauskas DA, Hawkins DS, Patiño-Garcia A, Lupo PJ, Scheurer ME, Morton L, Armstrong GT, Sapkota Y, Gramatges MM, Serra M, Hattinger C, Scotlandi K, Andrulis IL, Wunder JS, Ballinger ML, Thomas DM, Yeager M, Dean M, Stewart DR, Vogt A, Liu J, Hicks BD, Huang WY, Landi MT, Lori A, Diver WR, Savage SA, Chanock SJ, Mirabello L. Rafati M, et al. J Natl Cancer Inst. 2026 Jun 1;118(6):1120-1125. doi: 10.1093/jnci/djaf278. J Natl Cancer Inst. 2026. PMID: 40996338 Free PMC article.
Implementation of Comprehensive Surgical Guidelines for Hepatoblastoma: Analysis of the Children's Oncology Group AHEP0731 Phase III Trial.
Kastenberg ZJ, Vasudevan SA, Dolmadjian L, Langham MR, Piao J, Tiao GM, Dunn SP, McGahren ED, Towbin AJ, McCarville MB, Malogolowkin MH, Furman WL, Thompson PA, Finegold MJ, Ranganathan S, Lopez-Terrada D, Krailo M, Rodriguez-Galindo C, O'Neill AF, Katzenstein HM, Weldon CB, Meyers RL. Kastenberg ZJ, et al. Ann Surg. 2025 Sep 25. doi: 10.1097/SLA.0000000000006951. Online ahead of print. Ann Surg. 2025. PMID: 40996219
Caregivers' Perspectives on Changes in Family Life During B-ALL Therapy: A Qualitative Study From the Children's Oncology Group.
Dreyzin A, Ware M, Stumbras K, Kairalla J, Hibbitts E, Mossman B, Balsamo L, Rodwin R, Ness KK, Conley CC, Raetz E, Devidas M, Sung L, Loh M, Hunger SP, Schore RJ, Angiolillo A, Kadan-Lottick N. Dreyzin A, et al. Pediatr Blood Cancer. 2025 Dec;72(12):e32057. doi: 10.1002/pbc.32057. Epub 2025 Sep 19. Pediatr Blood Cancer. 2025. PMID: 40974099 Free PMC article.
Outcome of Children With Intermediate-Risk Extracranial Malignant Germ Cell Tumors by Response Status at the End of Induction Chemotherapy: A Report From the Children's Oncology Group.
Fonseca A, Villaluna D, Krailo M, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Billmire DF, Rescorla FJ, Ross JH, Dicken BJ, Rodriguez-Galindo C, Frazier L, Shaikh F. Fonseca A, et al. Pediatr Blood Cancer. 2025 Dec;72(12):e32033. doi: 10.1002/pbc.32033. Epub 2025 Sep 14. Pediatr Blood Cancer. 2025. PMID: 40947516 Free PMC article.
Advancing Preclinical Biology for Ewing Sarcoma: An International Effort.
Dela Cruz FS, Stewart EA, Surdez D, Daley JD, Soragni A, Tomazou EM, Alvarez-Perez J, Feinberg TY, Amatruda JF, Ganapathi SS, Ohm JE, Heske CM, Cohen-Gogo S, Pesic D, Nash JO, Shlien A, Roundhill EA, Burchill SA, Crompton BD, Lawlor ER, Loeb DM, Delattre O, Mora J, Scotlandi K, Reed DR, Grohar PJ, Grünewald TGP, Kovar H, Bailey KM. Dela Cruz FS, et al. Mol Cancer Ther. 2026 Jan 2;25(1):48-70. doi: 10.1158/1535-7163.MCT-25-0428. Mol Cancer Ther. 2026. PMID: 40911901 Free PMC article. Review.
New Approaches to Investigate Novel Agents in Ewing Sarcoma: A Report From the Children's Oncology Group Bone Tumor Committee.
Daley JD, Whiteway SL, Heske CM, Dela Cruz FS, Whittle SB, Cohen-Gogo S, Collier AB, Gupta A, Ohm J, Clark A, Soragni A, Lawlor E, Setty B, Grohar PJ, Janeway K, Reed DR, Slotkin EK, Bailey KM. Daley JD, et al. Pediatr Blood Cancer. 2025 Oct;72(10):e31917. doi: 10.1002/pbc.31917. Epub 2025 Jul 24. Pediatr Blood Cancer. 2025. PMID: 40879325 Free PMC article. Review.
Germline Pathogenic/Likely Pathogenic Mutations and Subsequent Neoplasms Among Childhood Cancer Survivors: A Report From the Children's Oncology Group ALTE03N1 Study.
Zhou L, Singh P, Crossman D, Richman J, Trainor P, Cheng C, Wang X, Sharafeldin N, Hageman L, Sheikh M, Richard MA, Friedman DN, Neglia JP, Wang Z, Hudson MM, Armenian SH, Hawkins D, Bhatia R, Landier W, Bhatia S. Zhou L, et al. J Clin Oncol. 2025 Sep 20;43(27):3011-3020. doi: 10.1200/JCO-25-00542. Epub 2025 Aug 19. J Clin Oncol. 2025. PMID: 40829087 Free PMC article.
Role of race and ethnicity in survival among children/young adults with relapsed ALL: a Children's Oncology Group report.
Ligon JA, Ji L, Dang A, Xu X, Rheingold SR, Bhojwani D, Devidas M, Kairalla JA, Shago M, Heerema NA, Carroll AJ, Borowitz M, Wood BL, Winick NJ, Carroll WL, Hunger SP, Raetz EA, Loh ML, Gupta S, Winestone LE. Ligon JA, et al. Blood Adv. 2025 Nov 25;9(22):5738-5751. doi: 10.1182/bloodadvances.2025016670. Blood Adv. 2025. PMID: 40815811 Free PMC article.
Childhood cancer data initiative: expanded access to tumor molecular profiling for children, adolescents, and young adults.
Flores-Toro J, Jagu S, Smith M, Shern J, Hawkins DS, Mardis ER, Rudzinski E, Alonzo TA, Beeles T, Ramirez N, Thomas DL, Cottrell CE, Parbhoo K, Janeway KA, Leary S, Fouladi M, Oberoi S, Venkatramani R, Irwin M, Laetsch TW, Chen KS, Bailey K, Davis JL, Sullivan MB, Boja E, Lowy D, Guidry Auvil JM, Wideman B, Kibbe W, Doroshow J, Reaman GH. Flores-Toro J, et al. J Natl Cancer Inst. 2026 Feb 1;118(2):199-204. doi: 10.1093/jnci/djaf214. J Natl Cancer Inst. 2026. PMID: 40794906 Free PMC article.
NAPRT expression and epigenetic regulation in pediatric rhabdomyosarcoma as a potential biomarker for NAMPT inhibition.
Kim A, Bhardwaj P, Heer CD, Zhao SJ, Lucas KN, Noronha KJ, Friedman S, Morotti R, Sundaram RK, Rehman S, Bhatt D, Cruz FSD, Feinberg TY, Ramakrishnan S, Xue W, Barkauskas DA, Hall D, Shern JF, Sun W, Barr FG, Yi JS, Spurrier J, Yu A, Brenner C, Heske CM, Vasquez JC. Kim A, et al. bioRxiv [Preprint]. 2025 Jul 31:2025.07.28.667284. doi: 10.1101/2025.07.28.667284. bioRxiv. 2025. Update in: Mol Cancer Ther. 2026 Apr 21. doi: 10.1158/1535-7163.MCT-25-0619. PMID: 40766550 Free PMC article. Updated. Preprint.
Epigenomic diagnosis and prognosis of Acute Myeloid Leukemia.
Marchi F, Shastri VM, Marrero RJ, Nguyen NHK, Öttl A, Schade AK, Landwehr M, Krali O, Nordlund J, Ghavami M, Sckaff F, Mansinghka VK, Cao X, Slayton W, Starostik P, Cogle CR, Ribeiro RC, Rubnitz JE, Klco J, Elsayed A, Gamis AS, Triche TJ Jr, Ries R, Kolb EA, Aplenc R, Alonzo T, Pounds S, Meshinchi S, Lamba JK. Marchi F, et al. Nat Commun. 2025 Jul 29;16(1):6961. doi: 10.1038/s41467-025-62005-4. Nat Commun. 2025. PMID: 40730747 Free PMC article.
Prioritization of novel agents for further investigation in pediatric non-rhabdomyosarcoma soft tissue sarcomas: A report from the Children's Oncology Group.
Crane JN, Douglass DP, Oberoi S, Collins NB, Gupta A, Metts JL, Avutu V, Dela Cruz FS, Davis JL, Federman NC, Hiniker SM, Laetsch TW, Linardic CM, Navid F, Saab R, Shulman DS, Shern JF, Soragni A, Stewart EA, Terezakis S, Weigel BJ, Weiss AR. Crane JN, et al. Eur J Cancer. 2025 Aug 26;226:115600. doi: 10.1016/j.ejca.2025.115600. Epub 2025 Jul 6. Eur J Cancer. 2025. PMID: 40651390 Free PMC article. Review.
Inferring chromosome segregation error stage and crossover in trisomic disorders with application to Down syndrome.
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Cytarabine Pharmacogenomics and Outcomes Among Children and Young Adults With Acute Myeloid Leukemia.
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Preoperative Radiotherapy in Patients With Localized Ewing Sarcoma Enrolled on AEWS1031: A Report From the Children's Oncology Group.
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DNA Damage Response and Repair Genes and Anthracycline-Induced Cardiomyopathy in Childhood Cancer Survivors: A Report From the Children's Oncology Group and the Childhood Cancer Survivor Study.
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