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Page 1
Urinary sodium/creatinine ratio is a predictor for fractional sodium excretion and related to age in patients with cystic fibrosis.
Declercq D, Peremans L, Glorieus M, Weygaerde YV, Schaballie H, Van Braeckel E, Snauwaert E, Van Daele S, Van Biervliet S. Declercq D, et al. Among authors: van daele s, van biervliet s, van braeckel e. J Cyst Fibros. 2022 Mar;21(2):e136-e140. doi: 10.1016/j.jcf.2021.11.002. Epub 2021 Nov 19. J Cyst Fibros. 2022. PMID: 34802939 Free article.
Gastro-intestinal manifestations in cystic fibrosis patients.
Van Biervliet S, de Clercq C, Declercq D, Van Braeckel E, Van Daele S, De Baets F, De Looze D. Van Biervliet S, et al. Among authors: van daele s, van braeckel e. Acta Gastroenterol Belg. 2016 Sep-Dec;79(4):481-486. Acta Gastroenterol Belg. 2016. PMID: 28209107 Free article. Review.
Development and validation of an LC tandem MS assay for the quantification of β-lactam antibiotics in the sputum of cystic fibrosis patients.
Forier K, Van Heck V, Carlier M, Van Braeckel E, Van Daele S, De Baets F, Schelstraete P, Haerynck F, Stove V, Van Simaey L, Vaneechoutte M, Verstraete AG. Forier K, et al. Among authors: van daele s, van simaey l, van braeckel e, van heck v. J Antimicrob Chemother. 2018 Jan 1;73(1):95-101. doi: 10.1093/jac/dkx331. J Antimicrob Chemother. 2018. PMID: 29029070
Establishing the diagnosis of chronic colonization with Pseudomonas aeruginosa of cystic fibrosis patients: Comparison of the European consensus criteria with genotyping of P. aeruginosa isolates.
Jonckheere L, Schelstraete P, Van Simaey L, Van Braeckel E, Willekens J, Van Daele S, De Baets F, Vaneechoutte M. Jonckheere L, et al. Among authors: van simaey l, van daele s, van braeckel e. J Cyst Fibros. 2018 Nov;17(6):729-735. doi: 10.1016/j.jcf.2018.03.004. Epub 2018 Apr 11. J Cyst Fibros. 2018. PMID: 29655935 Free article.
The nutritional status in CF: Being certain about the uncertainties.
Declercq D, Van Meerhaeghe S, Marchand S, Van Braeckel E, van Daele S, De Baets F, Van Biervliet S. Declercq D, et al. Among authors: van daele s, van biervliet s, van meerhaeghe s, van braeckel e. Clin Nutr ESPEN. 2019 Feb;29:15-21. doi: 10.1016/j.clnesp.2018.10.009. Epub 2018 Nov 7. Clin Nutr ESPEN. 2019. PMID: 30661680 Review.
CFTR activity is enhanced by the novel corrector GLPG2222, given with and without ivacaftor in two randomized trials.
Bell SC, Barry PJ, De Boeck K, Drevinek P, Elborn JS, Plant BJ, Minić P, Van Braeckel E, Verhulst S, Muller K, Kanters D, Bellaire S, de Kock H, Geller DE, Conrath K, Van de Steen O, van der Ent K. Bell SC, et al. Among authors: van de steen o, van der ent k, van braeckel e. J Cyst Fibros. 2019 Sep;18(5):700-707. doi: 10.1016/j.jcf.2019.04.014. Epub 2019 May 3. J Cyst Fibros. 2019. PMID: 31056441 Free article. Clinical Trial.
Haemoptysis as the first presentation of COVID-19: a case report.
Peys E, Stevens D, Weygaerde YV, Malfait T, Hermie L, Rogiers P, Depuydt P, Van Braeckel E. Peys E, et al. Among authors: van braeckel e. BMC Pulm Med. 2020 Oct 22;20(1):275. doi: 10.1186/s12890-020-01312-6. BMC Pulm Med. 2020. PMID: 33092563 Free PMC article.
Altered intravenous drug disposition in people living with cystic fibrosis: A meta-analysis integrating top-down and bottom-up data.
De Sutter PJ, Van Haeverbeke M, Van Braeckel E, Van Biervliet S, Van Bocxlaer J, Vermeulen A, Gasthuys E. De Sutter PJ, et al. Among authors: van haeverbeke m, van biervliet s, van braeckel e, van bocxlaer j. CPT Pharmacometrics Syst Pharmacol. 2022 Aug;11(8):951-966. doi: 10.1002/psp4.12832. Epub 2022 Jun 29. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35748042 Free PMC article. Review.
Factors associated with clinical progression to severe COVID-19 in people with cystic fibrosis: A global observational study.
Carr SB, McClenaghan E, Elbert A, Faro A, Cosgriff R, Abdrakhmanov O, Brownlee K, Burgel PR, Byrnes CA, Cheng SY, Colombo C, Corvol H, Daneau G, Goss CH, Gulmans V, Gutierrez H, Harutyunyan S, Helmick M, Jung A, Kashirskaya N, McKone E, Melo J, Middleton PG, Mondejar-Lopez P, de Monestrol I, Nährlich L, Padoan R, Parker M, Pastor-Vivero MD, Rizvi S, Ruseckaite R, Salvatore M, da Silva-Filho LVRF, Versmessen N, Zampoli M, Marshall BC, Stephenson AL; CF Registry Global Collaboration. Carr SB, et al. J Cyst Fibros. 2022 Jul;21(4):e221-e231. doi: 10.1016/j.jcf.2022.06.006. Epub 2022 Jun 13. J Cyst Fibros. 2022. PMID: 35753987 Free PMC article.
Glycemic indices at night measured by CGM are predictive for a lower pulmonary function in adults but not in children with cystic fibrosis.
Declercq D, Helleputte S, Marchand S, Van Aken S, Van Braeckel E, Van Daele S, T'Sjoen G, Van Biervliet S, Lapauw B. Declercq D, et al. Among authors: van daele s, van biervliet s, van braeckel e, van aken s. J Cyst Fibros. 2023 Jan;22(1):59-65. doi: 10.1016/j.jcf.2022.08.016. Epub 2022 Sep 6. J Cyst Fibros. 2023. PMID: 36068119
Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trial.
Sutharsan S, McKone EF, Downey DG, Duckers J, MacGregor G, Tullis E, Van Braeckel E, Wainwright CE, Watson D, Ahluwalia N, Bruinsma BG, Harris C, Lam AP, Lou Y, Moskowitz SM, Tian S, Yuan J, Waltz D, Mall MA; VX18-445-109 study group. Sutharsan S, et al. Among authors: van braeckel e. Lancet Respir Med. 2022 Mar;10(3):267-277. doi: 10.1016/S2213-2600(21)00454-9. Epub 2021 Dec 20. Lancet Respir Med. 2022. PMID: 34942085 Clinical Trial.
Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.
Middleton PG, Mall MA, Dřevínek P, Lands LC, McKone EF, Polineni D, Ramsey BW, Taylor-Cousar JL, Tullis E, Vermeulen F, Marigowda G, McKee CM, Moskowitz SM, Nair N, Savage J, Simard C, Tian S, Waltz D, Xuan F, Rowe SM, Jain R; VX17-445-102 Study Group. Middleton PG, et al. N Engl J Med. 2019 Nov 7;381(19):1809-1819. doi: 10.1056/NEJMoa1908639. Epub 2019 Oct 31. N Engl J Med. 2019. PMID: 31697873 Free PMC article. Clinical Trial.
Triple Therapy for Cystic Fibrosis Phe508del-Gating and -Residual Function Genotypes.
Barry PJ, Mall MA, Álvarez A, Colombo C, de Winter-de Groot KM, Fajac I, McBennett KA, McKone EF, Ramsey BW, Sutharsan S, Taylor-Cousar JL, Tullis E, Ahluwalia N, Jun LS, Moskowitz SM, Prieto-Centurion V, Tian S, Waltz D, Xuan F, Zhang Y, Rowe SM, Polineni D; VX18-445-104 Study Group. Barry PJ, et al. N Engl J Med. 2021 Aug 26;385(9):815-825. doi: 10.1056/NEJMoa2100665. N Engl J Med. 2021. PMID: 34437784 Free PMC article. Clinical Trial.
The short-term effects of ORKAMBI (lumacaftor/ivacaftor) on regional and distal lung structures using functional respiratory imaging.
Lauwers E, Belmans D, Mignot B, Ides K, Van Hoorenbeeck K, Snoeckx A, Van Holsbeke C, Nowé V, Van Braeckel E, De Backer W, De Backer J, Verhulst S. Lauwers E, et al. Among authors: van braeckel e, van hoorenbeeck k, van holsbeke c. Ther Adv Respir Dis. 2021 Jan-Dec;15:17534666211046774. doi: 10.1177/17534666211046774. Ther Adv Respir Dis. 2021. PMID: 34541955 Free PMC article.
Long-term safety and efficacy of tezacaftor-ivacaftor in individuals with cystic fibrosis aged 12 years or older who are homozygous or heterozygous for Phe508del CFTR (EXTEND): an open-label extension study.
Flume PA, Biner RF, Downey DG, Brown C, Jain M, Fischer R, De Boeck K, Sawicki GS, Chang P, Paz-Diaz H, Rubin JL, Yang Y, Hu X, Pasta DJ, Millar SJ, Campbell D, Wang X, Ahluwalia N, Owen CA, Wainwright CE; VX14-661-110 study group. Flume PA, et al. Lancet Respir Med. 2021 Jul;9(7):733-746. doi: 10.1016/S2213-2600(20)30510-5. Epub 2021 Feb 10. Lancet Respir Med. 2021. PMID: 33581080
Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.
Heijerman HGM, McKone EF, Downey DG, Van Braeckel E, Rowe SM, Tullis E, Mall MA, Welter JJ, Ramsey BW, McKee CM, Marigowda G, Moskowitz SM, Waltz D, Sosnay PR, Simard C, Ahluwalia N, Xuan F, Zhang Y, Taylor-Cousar JL, McCoy KS; VX17-445-103 Trial Group. Heijerman HGM, et al. Among authors: van braeckel e. Lancet. 2019 Nov 23;394(10212):1940-1948. doi: 10.1016/S0140-6736(19)32597-8. Epub 2019 Oct 31. Lancet. 2019. PMID: 31679946 Free PMC article. Clinical Trial.
Myotonic dystrophy type 1 as a major risk factor for severe COVID-19?
Dhont S, Callens R, Stevens D, Bauters F, De Bleecker JL, Derom E, Van Braeckel E. Dhont S, et al. Among authors: van braeckel e. Acta Neurol Belg. 2021 Dec;121(6):1761-1765. doi: 10.1007/s13760-020-01514-z. Epub 2020 Oct 14. Acta Neurol Belg. 2021. PMID: 33052531 Free PMC article.
Case Report: Convalescent Plasma, a Targeted Therapy for Patients with CVID and Severe COVID-19.
Van Damme KFA, Tavernier S, Van Roy N, De Leeuw E, Declercq J, Bosteels C, Maes B, De Bruyne M, Bogaert D, Bosteels V, Hoste L, Naesens L, Maes P, Grifoni A, Weiskopf D, Sette A, Depuydt P, Van Braeckel E, Haerynck F, Lambrecht BN. Van Damme KFA, et al. Among authors: van braeckel e, van roy n. Front Immunol. 2020 Nov 20;11:596761. doi: 10.3389/fimmu.2020.596761. eCollection 2020. Front Immunol. 2020. PMID: 33329586 Free PMC article.
Sensitivity and specificity of 14 SARS-CoV-2 serological assays and their diagnostic potential in RT-PCR negative COVID-19 infections.
Van Honacker E, Coorevits L, Boelens J, Verhasselt B, Van Braeckel E, Bauters F, De Bus L, Schelstraete P, Willems J, Vandendriessche S, Padalko E. Van Honacker E, et al. Among authors: van braeckel e. Acta Clin Belg. 2022 Apr;77(2):315-320. doi: 10.1080/17843286.2020.1861885. Epub 2020 Dec 22. Acta Clin Belg. 2022. PMID: 33350362 Free PMC article.
Diagnosing COVID-19; towards a feasible COVID-19 rule-out protocol.
De Clercq J, Malfait T, Malfait S, Boelens J, Coorevits L, Padalko E, Vandendriessche S, Verhasselt B, Morbée L, Bauters F, Hertegonne K, Stevens D, Vande Weygaerde Y, Vermaelen K, Van Biesen W, Vanommeslaeghe F, Verbeke F, Piers R, Van Den Noortgate N, Desmet T, Vermassen F, Vandekerckhove L, Van Braeckel E. De Clercq J, et al. Among authors: van biesen w, van braeckel e, van den noortgate n. Acta Clin Belg. 2022 Apr;77(2):368-376. doi: 10.1080/17843286.2021.1883362. Epub 2021 Feb 13. Acta Clin Belg. 2022. PMID: 33586631 Free PMC article.
Prospective longitudinal evaluation of hospitalised COVID-19 survivors 3 and 12 months after discharge.
Lorent N, Vande Weygaerde Y, Claeys E, Guler Caamano Fajardo I, De Vos N, De Wever W, Salhi B, Gyselinck I, Bosteels C, Lambrecht BN, Everaerts S, Verschraegen S, Schepers C, Demeyer H, Heyns A, Depuydt P, Oeyen S, Van Bleyenbergh P, Godinas L, Dupont L, Hermans G, Derom E, Gosselink R, Janssens W, Van Braeckel E. Lorent N, et al. Among authors: van braeckel e, van bleyenbergh p. ERJ Open Res. 2022 Apr 11;8(2):00004-2022. doi: 10.1183/23120541.00004-2022. eCollection 2022 Apr. ERJ Open Res. 2022. PMID: 35415186 Free PMC article.
Video-assisted thoracic surgery in critically ill COVID-19 patients on venovenous extracorporeal membrane oxygenation.
Zwaenepoel B, Vandewiele K, Peperstraete H, De Ryck F, Vanpeteghem C, Malfait T, Herck I, Vandenberghe W, Van Laethem L, Defreyne L, Van Braeckel E, Depuydt P, Schaubroeck H. Zwaenepoel B, et al. Among authors: van laethem l, van braeckel e. Perfusion. 2023 Nov;38(8):1577-1583. doi: 10.1177/02676591221119319. Epub 2022 Aug 15. Perfusion. 2023. PMID: 35969115 Free PMC article.
Case report: a student of Asian origin with Pott's disease.
Roggeman S, Buyck G, Petrovic M, Callens S, Van Braeckel E. Roggeman S, et al. Among authors: van braeckel e. Acta Clin Belg. 2016 Oct;71(5):340-342. doi: 10.1080/17843286.2016.1139318. Epub 2016 May 3. Acta Clin Belg. 2016. PMID: 27141824
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome.
Béziat V, Tavernier SJ, Chen YH, Ma CS, Materna M, Laurence A, Staal J, Aschenbrenner D, Roels L, Worley L, Claes K, Gartner L, Kohn LA, De Bruyne M, Schmitz-Abe K, Charbonnier LM, Keles S, Nammour J, Vladikine N, Maglorius Renkilaraj MRL, Seeleuthner Y, Migaud M, Rosain J, Jeljeli M, Boisson B, Van Braeckel E, Rosenfeld JA, Dai H, Burrage LC, Murdock DR, Lambrecht BN, Avettand-Fenoel V, Vogel TP; Undiagnosed Diseases Network; Esther CR, Haskologlu S, Dogu F, Ciznar P, Boutboul D, Ouachée-Chardin M, Amourette J, Lebras MN, Gauvain C, Tcherakian C, Ikinciogullari A, Beyaert R, Abel L, Milner JD, Grimbacher B, Couderc LJ, Butte MJ, Freeman AF, Catherinot É, Fieschi C, Chatila TA, Tangye SG, Uhlig HH, Haerynck F, Casanova JL, Puel A. Béziat V, et al. Among authors: van braeckel e. J Exp Med. 2020 Jun 1;217(6):e20191804. doi: 10.1084/jem.20191804. J Exp Med. 2020. PMID: 32207811 Free PMC article.
The pathophysiology of 'happy' hypoxemia in COVID-19.
Dhont S, Derom E, Van Braeckel E, Depuydt P, Lambrecht BN. Dhont S, et al. Among authors: van braeckel e. Respir Res. 2020 Jul 28;21(1):198. doi: 10.1186/s12931-020-01462-5. Respir Res. 2020. PMID: 32723327 Free PMC article. Review.
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.
Zhang Q, Bastard P, Liu Z, Le Pen J, Moncada-Velez M, Chen J, Ogishi M, Sabli IKD, Hodeib S, Korol C, Rosain J, Bilguvar K, Ye J, Bolze A, Bigio B, Yang R, Arias AA, Zhou Q, Zhang Y, Onodi F, Korniotis S, Karpf L, Philippot Q, Chbihi M, Bonnet-Madin L, Dorgham K, Smith N, Schneider WM, Razooky BS, Hoffmann HH, Michailidis E, Moens L, Han JE, Lorenzo L, Bizien L, Meade P, Neehus AL, Ugurbil AC, Corneau A, Kerner G, Zhang P, Rapaport F, Seeleuthner Y, Manry J, Masson C, Schmitt Y, Schlüter A, Le Voyer T, Khan T, Li J, Fellay J, Roussel L, Shahrooei M, Alosaimi MF, Mansouri D, Al-Saud H, Al-Mulla F, Almourfi F, Al-Muhsen SZ, Alsohime F, Al Turki S, Hasanato R, van de Beek D, Biondi A, Bettini LR, D'Angio' M, Bonfanti P, Imberti L, Sottini A, Paghera S, Quiros-Roldan E, Rossi C, Oler AJ, Tompkins MF, Alba C, Vandernoot I, Goffard JC, Smits G, Migeotte I, Haerynck F, Soler-Palacin P, Martin-Nalda A, Colobran R, Morange PE, Keles S, Çölkesen F, Ozcelik T, Yasar KK, Senoglu S, Karabela ŞN, Rodríguez-Gallego C, Novelli G, Hraiech S, Tandjaoui-Lambiotte Y, Duval X, Laouénan C; COVID-STORM Clinicians; COVID Clinicians; Imagine COVID Group; French COVID Cohort Study Group; CoV-Contact Cohort… See abstract for full author list ➔ Zhang Q, et al. Science. 2020 Oct 23;370(6515):eabd4570. doi: 10.1126/science.abd4570. Epub 2020 Sep 24. Science. 2020. PMID: 32972995 Free PMC article.
Treatment outcome definitions in chronic pulmonary aspergillosis: a CPAnet consensus statement.
Van Braeckel E, Page I, Davidsen JR, Laursen CB, Agarwal R, Alastruey-Izquierdo A, Barac A, Cadranel J, Chakrabarti A, Cornely OA, Denning DW, Flick H, Gangneux JP, Godet C, Hayashi Y, Hennequin C, Hoenigl M, Irfan M, Izumikawa K, Koh WJ, Kosmidis C, Lange C, Lamprecht B, Laurent F, Munteanu O, Oladele R, Patterson TF, Watanabe A, Salzer HJF; CPAnet. Van Braeckel E, et al. Eur Respir J. 2022 Jun 9;59(6):2102950. doi: 10.1183/13993003.02950-2021. Print 2022 Jun. Eur Respir J. 2022. PMID: 35236726 Free article. No abstract available.
An unusual presentation of a case of human psittacosis.
Vande Weygaerde Y, Versteele C, Thijs E, De Spiegeleer A, Boelens J, Vanrompay D, Van Braeckel E, Vermaelen K. Vande Weygaerde Y, et al. Among authors: van braeckel e. Respir Med Case Rep. 2018 Feb 2;23:138-142. doi: 10.1016/j.rmcr.2018.01.010. eCollection 2018. Respir Med Case Rep. 2018. PMID: 29719801 Free PMC article.
Bacterial etiology of community-acquired pneumonia in immunocompetent hospitalized patients and appropriateness of empirical treatment recommendations: an international point-prevalence study.
Carugati M, Aliberti S, Sotgiu G, Blasi F, Gori A, Menendez R, Encheva M, Gallego M, Leuschner P, Ruiz-Buitrago S, Battaglia S, Fantini R, Pascual-Guardia S, Marin-Corral J, Restrepo MI; GLIMP Collaborators. Carugati M, et al. Eur J Clin Microbiol Infect Dis. 2020 Aug;39(8):1513-1525. doi: 10.1007/s10096-020-03870-3. Epub 2020 Apr 3. Eur J Clin Microbiol Infect Dis. 2020. PMID: 32242314 Free PMC article.
Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trial.
Declercq J, Bosteels C, Van Damme K, De Leeuw E, Maes B, Vandecauter A, Vermeersch S, Delporte A, Demeyere B, Vuylsteke M, Lalla M, Smart T, Detalle L, Bouw R, Streffer J, Degeeter T, Vergotte M, Guisez T, Van Braeckel E, Van Der Straeten C, Lambrecht BN. Declercq J, et al. Among authors: van damme k, van braeckel e, van der straeten c. Trials. 2020 Nov 19;21(1):934. doi: 10.1186/s13063-020-04884-0. Trials. 2020. PMID: 33213529 Free PMC article. Clinical Trial.
Letter to the Editor: Premorbid Frailty is a better Prognostic Indicator than Age in Oldest-Old Hospitalized with COVID-19.
Piers R, Janssens W, Cobbaert K, Pattyn I, Westhovens I, Martens H, Van Puyvelde K, Maertens S, Guyssens V, Baeyens H, Buyck G, De Raes E, van Leeuwen ML, Mouton V, Dedecker D, Deschepper E, Van Braeckel E, Benoit D, Van Den Noortgate N. Piers R, et al. Among authors: van braeckel e, van puyvelde k, van den noortgate n, van leeuwen ml. J Am Med Dir Assoc. 2021 Mar;22(3):514-516. doi: 10.1016/j.jamda.2021.01.059. Epub 2021 Jan 18. J Am Med Dir Assoc. 2021. PMID: 33484639 Free PMC article. No abstract available.
Vaccine-associated enhanced disease: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data.
Munoz FM, Cramer JP, Dekker CL, Dudley MZ, Graham BS, Gurwith M, Law B, Perlman S, Polack FP, Spergel JM, Van Braeckel E, Ward BJ, Didierlaurent AM, Lambert PH; Brighton Collaboration Vaccine-associated Enhanced Disease Working Group. Munoz FM, et al. Among authors: van braeckel e. Vaccine. 2021 May 21;39(22):3053-3066. doi: 10.1016/j.vaccine.2021.01.055. Epub 2021 Feb 23. Vaccine. 2021. PMID: 33637387 Free PMC article. Review.
Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial.
Declercq J, Van Damme KFA, De Leeuw E, Maes B, Bosteels C, Tavernier SJ, De Buyser S, Colman R, Hites M, Verschelden G, Fivez T, Moerman F, Demedts IK, Dauby N, De Schryver N, Govaerts E, Vandecasteele SJ, Van Laethem J, Anguille S, van der Hilst J, Misset B, Slabbynck H, Wittebole X, Liénart F, Legrand C, Buyse M, Stevens D, Bauters F, Seys LJM, Aegerter H, Smole U, Bosteels V, Hoste L, Naesens L, Haerynck F, Vandekerckhove L, Depuydt P, van Braeckel E, Rottey S, Peene I, Van Der Straeten C, Hulstaert F, Lambrecht BN. Declercq J, et al. Among authors: van laethem j, van der hilst j, van braeckel e, van damme kfa, van der straeten c. Lancet Respir Med. 2021 Dec;9(12):1427-1438. doi: 10.1016/S2213-2600(21)00377-5. Epub 2021 Oct 29. Lancet Respir Med. 2021. PMID: 34756178 Free PMC article. Clinical Trial.
Safety and Outcomes of Amikacin Liposome Inhalation Suspension for Mycobacterium abscessus Pulmonary Disease: A NTM-NET study.
Henriette Zweijpfenning SM, Chiron R, Essink S, Schildkraut J, Akkerman OW, Aliberti S, Altenburg J, Arets B, van Braeckel E, Delaere B, Gohy S, Haarman E, Lorent N, McKew G, Morgan L, Wagner D, van Ingen J, Hoefsloot W. Henriette Zweijpfenning SM, et al. Among authors: van ingen j, van braeckel e. Chest. 2022 Jul;162(1):76-81. doi: 10.1016/j.chest.2022.01.015. Epub 2022 Jan 19. Chest. 2022. PMID: 35063454 Free PMC article. No abstract available.
Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19: an open-label randomized controlled trial.
De Leeuw E, Van Damme KFA, Declercq J, Bosteels C, Maes B, Tavernier SJ, Detalle L, Smart T, Glatt S, Debeuf N, Deckers J, Lameire S, Vandecasteele SJ, De Neve N, Demedts IK, Govaerts E, Knoop C, Vanhove K, Moutschen M, Terryn W, Depuydt P, Van Braeckel E, Haerynck F, Hendrickx TCJ, Parrein V, Lalla M, Brittain C, Lambrecht BN. De Leeuw E, et al. Among authors: van braeckel e, van damme kfa. Respir Res. 2022 Aug 9;23(1):202. doi: 10.1186/s12931-022-02126-2. Respir Res. 2022. PMID: 35945604 Free PMC article. Clinical Trial.
Validation of an enzyme-linked immunosorbent assay for the quantification of human IgG directed against the repeat region of the circumsporozoite protein of the parasite Plasmodium falciparum.
Clement F, Dewar V, Van Braeckel E, Desombere I, Dewerchin M, Swysen C, Demoitié MA, Jongert E, Cohen J, Leroux-Roels G, Cambron P. Clement F, et al. Among authors: van braeckel e. Malar J. 2012 Nov 22;11:384. doi: 10.1186/1475-2875-11-384. Malar J. 2012. PMID: 23173602 Free PMC article.
Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients.
Di Pasquale MF, Sotgiu G, Gramegna A, Radovanovic D, Terraneo S, Reyes LF, Rupp J, González Del Castillo J, Blasi F, Aliberti S, Restrepo MI; GLIMP Investigators. Di Pasquale MF, et al. Clin Infect Dis. 2019 Apr 24;68(9):1482-1493. doi: 10.1093/cid/ciy723. Clin Infect Dis. 2019. PMID: 31222287 Free PMC article.
Aspiration Risk Factors, Microbiology, and Empiric Antibiotics for Patients Hospitalized With Community-Acquired Pneumonia.
Marin-Corral J, Pascual-Guardia S, Amati F, Aliberti S, Masclans JR, Soni N, Rodriguez A, Sibila O, Sanz F, Sotgiu G, Anzueto A, Dimakou K, Petrino R, van de Garde E, Restrepo MI; GLIMP investigators. Marin-Corral J, et al. Chest. 2021 Jan;159(1):58-72. doi: 10.1016/j.chest.2020.06.079. Epub 2020 Jul 17. Chest. 2021. PMID: 32687909 Free article.
An international perspective on hospitalized patients with viral community-acquired pneumonia.
Radovanovic D, Sotgiu G, Jankovic M, Mahesh PA, Marcos PJ, Abdalla MI, Di Pasquale MF, Gramegna A, Terraneo S, Blasi F, Santus P, Aliberti S, Reyes LF, Restrepo MI; GLIMP Study Group. Radovanovic D, et al. Eur J Intern Med. 2019 Feb;60:54-70. doi: 10.1016/j.ejim.2018.10.020. Epub 2018 Nov 4. Eur J Intern Med. 2019. PMID: 30401576 Free PMC article.
CPAnet Registry-An International Chronic Pulmonary Aspergillosis Registry.
Laursen CB, Davidsen JR, Van Acker L, Salzer HJF, Seidel D, Cornely OA, Hoenigl M, Alastruey-Izquierdo A, Hennequin C, Godet C, Barac A, Flick H, Munteanu O, Van Braeckel E. Laursen CB, et al. Among authors: van braeckel e, van acker l. J Fungi (Basel). 2020 Jun 29;6(3):96. doi: 10.3390/jof6030096. J Fungi (Basel). 2020. PMID: 32610566 Free PMC article.
Correction: Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome.
Béziat V, Tavernier SJ, Chen YH, Ma CS, Materna M, Laurence A, Staal J, Aschenbrenner D, Roels L, Worley L, Claes K, Gartner L, Kohn LA, De Bruyne M, Schmitz-Abe K, Charbonnier LM, Keles S, Nammour J, Vladikine N, Luxman Maglorius Renkilaraj MR, Seeleuthner Y, Migaud M, Rosain J, Jeljeli M, Boisson B, Van Braeckel E, Rosenfeld JA, Dai H, Burrage LC, Murdock DR, Lambrecht BN, Avettand-Fenoel V, Vogel TP, Network UD, Esther CR, Haskologlu S, Dogu F, Ciznar P, Boutboul D, Ouachée-Chardin M, Amourette J, Lebras MN, Gauvain C, Tcherakian C, Ikinciogullari A, Beyaert R, Abel L, Milner JD, Grimbacher B, Couderc LJ, Butte MJ, Freeman AF, Catherinot É, Fieschi C, Chatila TA, Tangye SG, Uhlig HH, Haerynck F, Casanova JL, Puel A. Béziat V, et al. Among authors: van braeckel e. J Exp Med. 2020 Jun 1;217(7):e2019180405272020c. doi: 10.1084/jem.2019180405272020c. J Exp Med. 2020. PMID: 32516385 Free PMC article. No abstract available.
Correction to: Bacterial etiology of community-acquired pneumonia in immunocompetent hospitalized patients and appropriateness of empirical treatment recommendations: an international point-prevalence study.
Carugati M, Aliberti S, Sotgiu G, Blasi F, Gori A, Menendez R, Encheva M, Gallego M, Leuschner P, Ruiz-Buitrago S, Battaglia S, Fantini R, Pascual-Guardia S, Marin-Corral J, Restrepo MI; GLIMP Collaborators. Carugati M, et al. Eur J Clin Microbiol Infect Dis. 2021 Sep;40(9):2051. doi: 10.1007/s10096-021-04295-2. Eur J Clin Microbiol Infect Dis. 2021. PMID: 34313897 Free PMC article. No abstract available.
Vaccine-induced HIV seropositivity: a problem on the rise.
Van Braeckel E, Koutsoukos M, Bourguignon P, Clement F, McNally L, Leroux-Roels G. Van Braeckel E, et al. J Clin Virol. 2011 Apr;50(4):334-7. doi: 10.1016/j.jcv.2011.01.003. J Clin Virol. 2011. PMID: 21300566 Clinical Trial.
HIV vaccines: can CD4+ T cells be of help?
Van Braeckel E, Leroux-Roels G. Van Braeckel E, et al. Hum Vaccin Immunother. 2012 Dec 1;8(12):1795-8. doi: 10.4161/hv.21760. Epub 2012 Aug 21. Hum Vaccin Immunother. 2012. PMID: 22906935 Free PMC article.
Aspergillus and the Lung.
Janssens I, Lambrecht BN, Van Braeckel E. Janssens I, et al. Among authors: van braeckel e. Semin Respir Crit Care Med. 2024 Feb;45(1):3-20. doi: 10.1055/s-0043-1777259. Epub 2024 Jan 29. Semin Respir Crit Care Med. 2024. PMID: 38286136 Free PMC article. Review.
Objective sputum colour assessment and clinical outcomes in bronchiectasis: data from the European Bronchiectasis Registry (EMBARC).
Aliberti S, Ringshausen FC, Dhar R, Haworth CS, Loebinger MR, Dimakou K, Crichton ML, De Soyza A, Vendrell M, Burgel PR, McDonnell M, Skrgat S, Maiz Carro L, de Roux A, Sibila O, Bossios A, van der Eerden M, Kauppi P, Wilson R, Milenkovic B, Menendez R, Murris M, Borekci S, Munteanu O, Obradovic D, Nowinski A, Amorim A, Torres A, Lorent N, Van Braeckel E, Altenburg J, Shoemark A, Shteinberg M, Boersma W, Goeminne PC, Elborn JS, Hill AT, Welte T, Blasi F, Polverino E, Chalmers JD; EMBARC Registry Investigators. Aliberti S, et al. Among authors: van braeckel e. Eur Respir J. 2024 Apr 18;63(4):2301554. doi: 10.1183/13993003.01554-2023. Print 2024 Apr. Eur Respir J. 2024. PMID: 38609095 Free PMC article.
Baseline chest computed tomography for diagnosis of invasive aspergillosis in patients with acute myeloid leukaemia treated with intensive chemotherapy: A retrospective single-centre cohort study.
Janssens E, Huygens S, Moors I, Delie A, Kerre T, Vande Weygaerde Y, Van Braeckel E, Boelens J, Morbée L, Schauwvlieghe A. Janssens E, et al. Among authors: van braeckel e. Mycoses. 2024 Mar;67(3):e13715. doi: 10.1111/myc.13715. Mycoses. 2024. PMID: 38477367
A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19.
Van Damme KFA, Hoste L, Declercq J, De Leeuw E, Maes B, Martens L, Colman R, Browaeys R, Bosteels C, Verwaerde S, Vermeulen N, Lameire S, Debeuf N, Deckers J, Stordeur P, Depuydt P, Van Braeckel E, Vandekerckhove L, Guilliams M, Schetters STT, Haerynck F, Tavernier SJ, Lambrecht BN. Van Damme KFA, et al. Among authors: van braeckel e. Sci Transl Med. 2023 Aug 23;15(710):eadi0252. doi: 10.1126/scitranslmed.adi0252. Epub 2023 Aug 23. Sci Transl Med. 2023. PMID: 37611083
Bronchiectasis and asthma: Data from the European Bronchiectasis Registry (EMBARC).
Polverino E, Dimakou K, Traversi L, Bossios A, Haworth CS, Loebinger MR, De Soyza A, Vendrell M, Burgel PR, Mertsch P, McDonnell M, Škrgat S, Maiz Carro L, Sibila O, van der Eerden M, Kauppi P, Hill AT, Wilson R, Milenkovic B, Menendez R, Murris M, Digalaki T, Crichton ML, Borecki S, Obradovic D, Nowinski A, Amorim A, Torres A, Lorent N, Welte T, Blasi F, Van Braeckel E, Altenburg J, Shoemark A, Shteinberg M, Boersma W, Elborn JS, Aliberti S, Ringshausen FC, Chalmers JD, Goeminne PC; EMBARC registry investigators. Polverino E, et al. Among authors: van braeckel e. J Allergy Clin Immunol. 2024 Feb 23:S0091-6749(24)00189-1. doi: 10.1016/j.jaci.2024.01.027. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 38401857 Free article.
The Spectrum of Pulmonary Aspergillosis.
Van Braeckel E, Cornely OA. Van Braeckel E, et al. Semin Respir Crit Care Med. 2024 Feb;45(1):1-2. doi: 10.1055/s-0043-1778126. Epub 2024 Jan 29. Semin Respir Crit Care Med. 2024. PMID: 38286135 No abstract available.
Mycobacterium avium complex pulmonary disease patients with limited treatment options.
Aliberti S, Blasi F, Burgel PR, Calcagno A, Fløe A, Grogono D, Papavasileiou A, Polverino E, Prados C, Rohde G, Salzer HJF, Sánchez-Montalvá A, Shteinberg M, Van Braeckel E, van Ingen J, Veziris N, Wagner D, Loebinger MR. Aliberti S, et al. Among authors: van braeckel e. ERJ Open Res. 2024 Jan 15;10(1):00610-2023. doi: 10.1183/23120541.00610-2023. eCollection 2024 Jan. ERJ Open Res. 2024. PMID: 38226066 Free PMC article.
Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.
Matuozzo D, Talouarn E, Marchal A, Zhang P, Manry J, Seeleuthner Y, Zhang Y, Bolze A, Chaldebas M, Milisavljevic B, Gervais A, Bastard P, Asano T, Bizien L, Barzaghi F, Abolhassani H, Tayoun AA, Aiuti A, Darazam IA, Allende LM, Alonso-Arias R, Arias AA, Aytekin G, Bergman P, Bondesan S, Bryceson YT, Bustos IG, Cabrera-Marante O, Carcel S, Carrera P, Casari G, Chaïbi K, Colobran R, Condino-Neto A, Covill LE, Delmonte OM, Zein LE, Flores C, Gregersen PK, Gut M, Haerynck F, Halwani R, Hancerli S, Hammarström L, Hatipoğlu N, Karbuz A, Keles S, Kyheng C, Leon-Lopez R, Franco JL, Mansouri D, Martinez-Picado J, Akcan OM, Migeotte I, Morange PE, Morelle G, Martin-Nalda A, Novelli G, Novelli A, Ozcelik T, Palabiyik F, Pan-Hammarström Q, de Diego RP, Planas-Serra L, Pleguezuelo DE, Prando C, Pujol A, Reyes LF, Rivière JG, Rodriguez-Gallego C, Rojas J, Rovere-Querini P, Schlüter A, Shahrooei M, Sobh A, Soler-Palacin P, Tandjaoui-Lambiotte Y, Tipu I, Tresoldi C, Troya J, van de Beek D, Zatz M, Zawadzki P, Al-Muhsen SZ, Alosaimi MF, Alsohime FM, Baris-Feldman H, Butte MJ, Constantinescu SN, Cooper MA, Dalgard CL, Fellay J, Heath JR, Lau YL, Lifton RP, Maniatis T, Mogensen TH, von Bernuth H, Le… See abstract for full author list ➔ Matuozzo D, et al. Genome Med. 2024 Jan 6;16(1):6. doi: 10.1186/s13073-023-01278-0. Genome Med. 2024. PMID: 38184654 Free PMC article. No abstract available.
Pooling isolates to address the diversity in antimicrobial susceptibility of Pseudomonas aeruginosa in cystic fibrosis.
Van den Bossche S, Abatih E, Grassi L, De Broe E, Rigole P, Boelens J, Van Caenegem J, Verhasselt B, Janssens I, Van Braeckel E, Versmessen N, Cools P, Coenye T, Crabbé A. Van den Bossche S, et al. Among authors: van braeckel e. Microbiol Spectr. 2023 Dec 12;11(6):e0044923. doi: 10.1128/spectrum.00449-23. Epub 2023 Nov 20. Microbiol Spectr. 2023. PMID: 37982625 Free PMC article.
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.
Matuozzo D, Talouarn E, Marchal A, Zhang P, Manry J, Seeleuthner Y, Zhang Y, Bolze A, Chaldebas M, Milisavljevic B, Gervais A, Bastard P, Asano T, Bizien L, Barzaghi F, Abolhassani H, Abou Tayoun A, Aiuti A, Alavi Darazam I, Allende LM, Alonso-Arias R, Arias AA, Aytekin G, Bergman P, Bondesan S, Bryceson YT, Bustos IG, Cabrera-Marante O, Carcel S, Carrera P, Casari G, Chaïbi K, Colobran R, Condino-Neto A, Covill LE, Delmonte OM, El Zein L, Flores C, Gregersen PK, Gut M, Haerynck F, Halwani R, Hancerli S, Hammarström L, Hatipoğlu N, Karbuz A, Keles S, Kyheng C, Leon-Lopez R, Franco JL, Mansouri D, Martinez-Picado J, Metin Akcan O, Migeotte I, Morange PE, Morelle G, Martin-Nalda A, Novelli G, Novelli A, Ozcelik T, Palabiyik F, Pan-Hammarström Q, de Diego RP, Planas-Serra L, Pleguezuelo DE, Prando C, Pujol A, Reyes LF, Rivière JG, Rodriguez-Gallego C, Rojas J, Rovere-Querini P, Schlüter A, Shahrooei M, Sobh A, Soler-Palacin P, Tandjaoui-Lambiotte Y, Tipu I, Tresoldi C, Troya J, van de Beek D, Zatz M, Zawadzki P, Al-Muhsen SZ, Alosaimi MF, Alsohime FM, Baris-Feldman H, Butte MJ, Constantinescu SN, Cooper MA, Dalgard CL, Fellay J, Heath JR, Lau YL, Lifton RP, Maniatis T, Mogensen TH, v… See abstract for full author list ➔ Matuozzo D, et al. Genome Med. 2023 Apr 5;15(1):22. doi: 10.1186/s13073-023-01173-8. Genome Med. 2023. PMID: 37020259 Free PMC article.
Safety and efficacy of vanzacaftor-tezacaftor-deutivacaftor in adults with cystic fibrosis: randomised, double-blind, controlled, phase 2 trials.
Uluer AZ, MacGregor G, Azevedo P, Indihar V, Keating C, Mall MA, McKone EF, Ramsey BW, Rowe SM, Rubenstein RC, Taylor-Cousar JL, Tullis E, Yonker LM, Chu C, Lam AP, Nair N, Sosnay PR, Tian S, Van Goor F, Viswanathan L, Waltz D, Wang LT, Xi Y, Billings J, Horsley A; VX18-121-101; VX18-561-101 Study Groups. Uluer AZ, et al. Lancet Respir Med. 2023 Jun;11(6):550-562. doi: 10.1016/S2213-2600(22)00504-5. Epub 2023 Feb 23. Lancet Respir Med. 2023. PMID: 36842446 Free article. Clinical Trial.
Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment.
Bosteels C, Van Damme KFA, De Leeuw E, Declercq J, Maes B, Bosteels V, Hoste L, Naesens L, Debeuf N, Deckers J, Cole B, Pardons M, Weiskopf D, Sette A, Weygaerde YV, Malfait T, Vandecasteele SJ, Demedts IK, Slabbynck H, Allard S, Depuydt P, Van Braeckel E, De Clercq J, Martens L, Dupont S, Seurinck R, Vandamme N, Haerynck F, Roychowdhury DF, Vandekerckhove L, Guilliams M, Tavernier SJ, Lambrecht BN. Bosteels C, et al. Among authors: van braeckel e, van damme kfa. Cell Rep Med. 2022 Dec 20;3(12):100833. doi: 10.1016/j.xcrm.2022.100833. Epub 2022 Nov 15. Cell Rep Med. 2022. PMID: 36459994 Free PMC article.
VX-445-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles.
Keating D, Marigowda G, Burr L, Daines C, Mall MA, McKone EF, Ramsey BW, Rowe SM, Sass LA, Tullis E, McKee CM, Moskowitz SM, Robertson S, Savage J, Simard C, Van Goor F, Waltz D, Xuan F, Young T, Taylor-Cousar JL; VX16-445-001 Study Group. Keating D, et al. N Engl J Med. 2018 Oct 25;379(17):1612-1620. doi: 10.1056/NEJMoa1807120. Epub 2018 Oct 18. N Engl J Med. 2018. PMID: 30334692 Free PMC article. Clinical Trial.