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Page 1
Small Leucine-Rich Proteoglycans in Tendon Wound Healing.
Xu X, Ha P, Yen E, Li C, Zheng Z. Xu X, et al. Among authors: yen e. Adv Wound Care (New Rochelle). 2022 Apr;11(4):202-214. doi: 10.1089/wound.2021.0069. Epub 2021 Dec 31. Adv Wound Care (New Rochelle). 2022. PMID: 34978952 Review.
GFER Represents a Target for Dual Disruption of Redox Homeostasis and Reactivation of the Immune Response in Pancreatic Adenocarcinoma.
Chen Z, Ho IL, Liu J, Soeung M, Yen EY, Sainani S, Dyke CA, Shah R, Kwon HJ, Han G, Yan X, Zhang S, Srinivasan S, Rose JL, Citron F, Jiang S, Chang Q, Feng N, Genovese G, Gao S, Yao W, Wang L, Wang H, Ying H, Viale A, Draetta GF. Chen Z, et al. Among authors: yen ey. Cancer Res. 2025 Dec 2. doi: 10.1158/0008-5472.CAN-24-4211. Online ahead of print. Cancer Res. 2025. PMID: 41329747
KRAS Inhibition Activates an Actionable CD24 "Do Not Eat Me" Signal in Pancreatic Cancer.
Wei Y, Liu M, Yen EY, Yao J, Xun Z, Nguyen PT, Wang X, Yang Z, Yousef A, Pan D, Jin Y, Li CF, Theardy MS, Park J, Cai Y, Takeda M, Vasquez M, Park EM, Peng DH, Zhou Y, Zhao H, Heffernan TP, Viale A, Wang H, Watowich SS, Liang H, Zhao D, DePinho RA, Yao W, Ying H. Wei Y, et al. Among authors: yen ey. Cancer Res. 2025 Dec 1;85(23):4825-4838. doi: 10.1158/0008-5472.CAN-25-2024. Cancer Res. 2025. PMID: 40966362 Free PMC article.
The Clinical Utility of Precision-Guided Dosing for Adalimumab Therapy Optimization in Inflammatory Bowel Disease: A Clinical Experience Program.
Hanauer SB, Torres EA, Aragon-Han P, Chapman JC, Swaminath AC, Arai R, Butnariu M, Lee TC, Rabizadeh S, Check M, Barrett TA, Hashash JG, Meister T, Yen EF, Kinnucan J, Stein DJ, Ziring D, Shaposhnikov R, Sinh P, Qazi TM, Yarur AJ, Monzur F, Dervieux T, Abraham BP. Hanauer SB, et al. Among authors: yen ef. Pharmaceutics. 2025 Mar 27;17(4):428. doi: 10.3390/pharmaceutics17040428. Pharmaceutics. 2025. PMID: 40284422 Free PMC article.
WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer.
Citron F, Ho IL, Balestrieri C, Liu Z, Yen EN, Cecchetto L, Perelli L, Zhang L, Castillo Montanez LA, Blazanin N, Dyke CA, Shah R, Attanasio S, Srinivasan S, Chen KC, Chen Z, Scognamiglio I, Pham N, Khan H, Jiang S, Pan J, Vanderkruk B, Leung C, Mattohti M, Rai K, Chu Y, Wang L, Gao S, Deem AK, Carugo A, Wang H, Yao W, Tonon G, Xiong Y, Lorenzi PL, Bonini C, Zal A, Hoffman B, Giuliani V, Heffernan T, Jeter CR, Lissanu Y, Genovese G, Di Pilato M, Viale A, Draetta GF. Citron F, et al. bioRxiv [Preprint]. 2025 Jan 2:2024.10.21.619543. doi: 10.1101/2024.10.21.619543. bioRxiv. 2025. PMID: 39484624 Free PMC article. Preprint.
Safety and Tolerability of CP101, a Full-Spectrum, Oral Microbiome Therapeutic for the Prevention of Recurrent Clostridioides difficile Infection: A Phase 2 Randomized Controlled Trial.
Allegretti JR, Kelly CR, Louie T, Fischer M, Hota S, Misra B, Van Hise NW, Yen E, Bullock JS, Silverman M, Davis I, McGill SK, Pardi DS, Orenstein R, Grinspan A, El-Nachef N, Feuerstadt P, Borody TJ, Khanna S, Budree S, Kassam Z. Allegretti JR, et al. Among authors: yen e. Gastroenterology. 2025 Feb;168(2):357-366.e3. doi: 10.1053/j.gastro.2024.09.030. Epub 2024 Oct 2. Gastroenterology. 2025. PMID: 39366468 Clinical Trial.
Correction to: Integrated Safety and Efficacy Analyses of Phase 3 Trials of a Microbiome Therapeutic for Recurrent CDI.
Kraft CS, Sims M, Silverman M, Louie TJ, Feuerstadt P, Huang ES, Khanna S, Berenson CS, Wang EEL, Cohen SH, Korman L, Lee C, Kelly CR, Odio A, Cook PP, Lashner B, Ramesh M, Kumar P, De A, Memisoglu A, Lombardi DA, Hasson BR, McGovern BH, von Moltke L, Pardi DS; ECOSPOR III and ECOSPOR IV investigators. Kraft CS, et al. Infect Dis Ther. 2024 Oct;13(10):2209-2210. doi: 10.1007/s40121-024-01036-8. Infect Dis Ther. 2024. PMID: 39212853 Free PMC article. No abstract available.
Integrated Safety and Efficacy Analyses of Phase 3 Trials of a Microbiome Therapeutic for Recurrent CDI.
Kraft CS, Sims M, Silverman M, Louie TJ, Feuerstadt P, Huang ES, Khanna S, Berenson CS, Wang EEL, Cohen SH, Korman L, Lee C, Kelly CR, Odio A, Cook PP, Lashner B, Ramesh M, Kumar P, De A, Memisoglu A, Lombardi DA, Hasson BR, McGovern BH, von Moltke L, Pardi DS; ECOSPOR III and ECOSPOR IV investigators. Kraft CS, et al. Infect Dis Ther. 2024 Oct;13(10):2105-2121. doi: 10.1007/s40121-024-01007-z. Epub 2024 Jun 28. Infect Dis Ther. 2024. PMID: 38941068 Free PMC article.
Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer.
Cortesi A, Gandolfi F, Arco F, Di Chiaro P, Valli E, Polletti S, Noberini R, Gualdrini F, Attanasio S, Citron F, Ho IL, Shah R, Yen EY, Spinella MC, Ronzoni S, Rodighiero S, Mitro N, Bonaldi T, Ghisletti S, Monticelli S, Viale A, Diaferia GR, Natoli G. Cortesi A, et al. Among authors: yen ey. Sci Adv. 2024 Mar 29;10(13):eadk5386. doi: 10.1126/sciadv.adk5386. Epub 2024 Mar 27. Sci Adv. 2024. PMID: 38536927 Free PMC article.
Clonal dominance defines metastatic dissemination in pancreatic cancer.
Ho IL, Li CY, Wang F, Zhao L, Liu J, Yen EY, Dyke CA, Shah R, Liu Z, Çetin AO, Chu Y, Citron F, Attanasio S, Corti D, Darbaniyan F, Del Poggetto E, Loponte S, Liu J, Soeung M, Chen Z, Jiang S, Jiang H, Inoue A, Gao S, Deem A, Feng N, Ying H, Kim M, Giuliani V, Genovese G, Zhang J, Futreal A, Maitra A, Heffernan T, Wang L, Do KA, Gargiulo G, Draetta G, Carugo A, Lin R, Viale A. Ho IL, et al. Among authors: yen ey. Sci Adv. 2024 Mar 15;10(11):eadd9342. doi: 10.1126/sciadv.add9342. Epub 2024 Mar 13. Sci Adv. 2024. PMID: 38478609 Free article.
Segmenting hypothalamic subunits in human newborn magnetic resonance imaging data.
Rasmussen JM, Wang Y, Graham AM, Fair DA, Posner J, O'Connor TG, Simhan HN, Yen E, Madan N, Entringer S, Wadhwa PD, Buss C; program collaborators for Environmental influences on Child Health Outcomes. Rasmussen JM, et al. Among authors: yen e. Hum Brain Mapp. 2024 Feb 1;45(2):e26582. doi: 10.1002/hbm.26582. Hum Brain Mapp. 2024. PMID: 38339904 Free PMC article.
KRAS Inhibition Activates an Actionable CD24 "Don't Eat Me" Signal in Pancreatic Cancer.
Wei Y, Liu M, Yen EY, Yao J, Xun Z, Nguyen PT, Wang X, Yang Z, Yousef A, Pan D, Jin Y, Li CF, Theardy MS, Park J, Cai Y, Takeda M, Vasquez M, Park EM, Peng DH, Zhou Y, Zhao H, Heffernan TP, Viale A, Wang H, Watowich SS, Liang H, Zhao D, DePinho RA, Yao W, Ying H. Wei Y, et al. bioRxiv [Preprint]. 2025 Sep 13:2023.09.21.558891. doi: 10.1101/2023.09.21.558891. bioRxiv. 2025. Update in: Cancer Res. 2025 Dec 1;85(23):4825-4838. doi: 10.1158/0008-5472.CAN-25-2024. PMID: 37790498 Free PMC article. Updated. Preprint.
Mirikizumab as Induction and Maintenance Therapy for Ulcerative Colitis.
D'Haens G, Dubinsky M, Kobayashi T, Irving PM, Howaldt S, Pokrotnieks J, Krueger K, Laskowski J, Li X, Lissoos T, Milata J, Morris N, Arora V, Milch C, Sandborn W, Sands BE; LUCENT Study Group. D'Haens G, et al. N Engl J Med. 2023 Jun 29;388(26):2444-2455. doi: 10.1056/NEJMoa2207940. N Engl J Med. 2023. PMID: 37379135 Clinical Trial.
Health Equity Implications of Missing Data Among Youths With Childhood-Onset Systemic Lupus Erythematosus: A Proof-of-Concept Study in the Childhood Arthritis and Rheumatology Research Alliance Registry.
Woo JMP, Simmonds F, Dennos A, Son MBF, Lewandowski LB, Rubinstein TB; CARRA Registry investigators. Woo JMP, et al. Arthritis Care Res (Hoboken). 2023 Nov;75(11):2285-2294. doi: 10.1002/acr.25136. Epub 2023 May 30. Arthritis Care Res (Hoboken). 2023. PMID: 37093036 Free PMC article.
Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis.
Chen Z, Ho IL, Soeung M, Yen EY, Liu J, Yan L, Rose JL, Srinivasan S, Jiang S, Edward Chang Q, Feng N, Gay JP, Wang Q, Wang J, Lorenzi PL, Veillon LJ, Wei B, Weinstein JN, Deem AK, Gao S, Genovese G, Viale A, Yao W, Lyssiotis CA, Marszalek JR, Draetta GF, Ying H. Chen Z, et al. Nat Commun. 2023 Apr 17;14(1):2194. doi: 10.1038/s41467-023-37924-9. Nat Commun. 2023. PMID: 37069167 Free PMC article.
Vedolizumab for the Treatment of Chronic Pouchitis.
Travis S, Silverberg MS, Danese S, Gionchetti P, Löwenberg M, Jairath V, Feagan BG, Bressler B, Ferrante M, Hart A, Lindner D, Escher A, Jones S, Shen B; EARNEST Study Group. Travis S, et al. N Engl J Med. 2023 Mar 30;388(13):1191-1200. doi: 10.1056/NEJMoa2208450. N Engl J Med. 2023. PMID: 36988594 Clinical Trial.
Childhood-Onset Lupus Nephritis in the Childhood Arthritis and Rheumatology Research Alliance Registry: Short-Term Kidney Status and Variation in Care.
Smitherman EA, Chahine RA, Beukelman T, Lewandowski LB, Rahman AKMF, Wenderfer SE, Curtis JR, Hersh AO; CARRA Registry Investigators. Smitherman EA, et al. Arthritis Care Res (Hoboken). 2023 Jul;75(7):1553-1562. doi: 10.1002/acr.25002. Epub 2023 Feb 12. Arthritis Care Res (Hoboken). 2023. PMID: 36775844 Free PMC article.
The Art, Science, and Secrets of Scanning Young Children.
Spann MN, Wisnowski JL; HBCD Phase I Scanning Young Populations Working Group; Smyser CD; Fetal, Infant, and Toddler Neuroimaging Group (FIT'NG); Howell B, Dean DC 3rd. Spann MN, et al. Biol Psychiatry. 2023 May 15;93(10):858-860. doi: 10.1016/j.biopsych.2022.09.025. Epub 2022 Sep 29. Biol Psychiatry. 2023. PMID: 36336497 Free PMC article. No abstract available.
Disease Recapture Rates After Medication Discontinuation and Flare in Juvenile Idiopathic Arthritis: An Observational Study Within the Childhood Arthritis and Rheumatology Research Alliance Registry.
Ringold S, Dennos AC, Kimura Y, Beukelman T, Shrader P, Phillips TA, Kohlheim M, Schanberg LE, Yeung RSM, Horton DB; Childhood Arthritis and Rheumatology Research Alliance Registry Investigators. Ringold S, et al. Arthritis Care Res (Hoboken). 2023 Apr;75(4):715-723. doi: 10.1002/acr.24994. Epub 2022 Dec 21. Arthritis Care Res (Hoboken). 2023. PMID: 35921198
Performance of the new biological small- and wide-angle X-ray scattering beamline 13A at the Taiwan Photon Source.
Shih O, Liao KF, Yeh YQ, Su CJ, Wang CA, Chang JW, Wu WR, Liang CC, Lin CY, Lee TH, Chang CH, Chiang LC, Chang CF, Liu DG, Lee MH, Liu CY, Hsu TW, Mansel B, Ho MC, Shu CY, Lee F, Yen E, Lin TC, Jeng U. Shih O, et al. Among authors: yen e. J Appl Crystallogr. 2022 Mar 18;55(Pt 2):340-352. doi: 10.1107/S1600576722001923. eCollection 2022 Apr 1. J Appl Crystallogr. 2022. PMID: 35497659 Free PMC article.
Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis.
Del Poggetto E, Ho IL, Balestrieri C, Yen EY, Zhang S, Citron F, Shah R, Corti D, Diaferia GR, Li CY, Loponte S, Carbone F, Hayakawa Y, Valenti G, Jiang S, Sapio L, Jiang H, Dey P, Gao S, Deem AK, Rose-John S, Yao W, Ying H, Rhim AD, Genovese G, Heffernan TP, Maitra A, Wang TC, Wang L, Draetta GF, Carugo A, Natoli G, Viale A. Del Poggetto E, et al. Among authors: yen ey. Science. 2021 Sep 17;373(6561):eabj0486. doi: 10.1126/science.abj0486. Epub 2021 Sep 17. Science. 2021. PMID: 34529467 Free PMC article.
Immune Phenotype and Response to Neoadjuvant Therapy in Triple-Negative Breast Cancer.
Yam C, Yen EY, Chang JT, Bassett RL, Alatrash G, Garber H, Huo L, Yang F, Philips AV, Ding QQ, Lim B, Ueno NT, Kannan K, Sun X, Sun B, Parra Cuentas ER, Symmans WF, White JB, Ravenberg E, Seth S, Guerriero JL, Rauch GM, Damodaran S, Litton JK, Wargo JA, Hortobagyi GN, Futreal A, Wistuba II, Sun R, Moulder SL, Mittendorf EA. Yam C, et al. Among authors: yen ey. Clin Cancer Res. 2021 Oct 1;27(19):5365-5375. doi: 10.1158/1078-0432.CCR-21-0144. Clin Cancer Res. 2021. PMID: 34253579 Free PMC article. Clinical Trial.
Improved Disease Course Associated With Early Initiation of Biologics in Polyarticular Juvenile Idiopathic Arthritis: Trajectory Analysis of a Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans Study.
Ong MS, Ringold S, Kimura Y, Schanberg LE, Tomlinson GA, Natter MD; CARRA Registry Investigators. Ong MS, et al. Arthritis Rheumatol. 2021 Oct;73(10):1910-1920. doi: 10.1002/art.41892. Epub 2021 Aug 27. Arthritis Rheumatol. 2021. PMID: 34105303
Consensus Treatment Plans for Severe Pediatric Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.
Morishita KA, Wagner-Weiner L, Yen EY, Sivaraman V, James KE, Gerstbacher D, Szymanski AM, O'Neil KM, Cabral DA; Childhood Arthritis and Rheumatology Research Alliance (CARRA) Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Workgroup. Morishita KA, et al. Among authors: yen ey. Arthritis Care Res (Hoboken). 2022 Sep;74(9):1550-1558. doi: 10.1002/acr.24590. Epub 2022 Jun 1. Arthritis Care Res (Hoboken). 2022. PMID: 33675161 Review.
Bile Acid Sequestrant Therapy in Microscopic Colitis.
Northcutt MJ, Gentile NM, Goldstein JL, Yen EF. Northcutt MJ, et al. J Clin Gastroenterol. 2022 Feb 1;56(2):161-165. doi: 10.1097/MCG.0000000000001496. J Clin Gastroenterol. 2022. PMID: 33443968
Fecal Microbiota Transplantation Is Highly Effective in Real-World Practice: Initial Results From the FMT National Registry.
Kelly CR, Yen EF, Grinspan AM, Kahn SA, Atreja A, Lewis JD, Moore TA, Rubin DT, Kim AM, Serra S, Nersesova Y, Fredell L, Hunsicker D, McDonald D, Knight R, Allegretti JR, Pekow J, Absah I, Hsu R, Vincent J, Khanna S, Tangen L, Crawford CV, Mattar MC, Chen LA, Fischer M, Arsenescu RI, Feuerstadt P, Goldstein J, Kerman D, Ehrlich AC, Wu GD, Laine L. Kelly CR, et al. Gastroenterology. 2021 Jan;160(1):183-192.e3. doi: 10.1053/j.gastro.2020.09.038. Epub 2020 Oct 1. Gastroenterology. 2021. PMID: 33011173 Free PMC article.
Consensus treatment plans for periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (PFAPA): a framework to evaluate treatment responses from the childhood arthritis and rheumatology research alliance (CARRA) PFAPA work group.
Amarilyo G, Rothman D, Manthiram K, Edwards KM, Li SC, Marshall GS, Yildirim-Toruner C, Haines K, Ferguson PJ, Lionetti G, Cherian J, Zhao Y, DeLaMora P, Syverson G, Nativ S, Twilt M, Michelow IC, Stepanovskiy Y, Thatayatikom A, Harel L, Akoghlanian S, Tucker L, Marques MC, Srinivasalu H, Propst EJ, Licameli GR, Dedeoglu F, Lapidus S; CARRA PFAPA Consensus Treatment Plan Workgroup. Amarilyo G, et al. Pediatr Rheumatol Online J. 2020 Apr 15;18(1):31. doi: 10.1186/s12969-020-00424-x. Pediatr Rheumatol Online J. 2020. PMID: 32293478 Free PMC article.
Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment.
Dey P, Li J, Zhang J, Chaurasiya S, Strom A, Wang H, Liao WT, Cavallaro F, Denz P, Bernard V, Yen EY, Genovese G, Gulhati P, Liu J, Chakravarti D, Deng P, Zhang T, Carbone F, Chang Q, Ying H, Shang X, Spring DJ, Ghosh B, Putluri N, Maitra A, Wang YA, DePinho RA. Dey P, et al. Cancer Discov. 2020 Apr;10(4):608-625. doi: 10.1158/2159-8290.CD-19-0297. Epub 2020 Feb 11. Cancer Discov. 2020. PMID: 32046984 Free PMC article.
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