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361 results
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Page 1
DFV890: a new oral NLRP3 inhibitor-tested in an early phase 2a randomised clinical trial in patients with COVID-19 pneumonia and impaired respiratory function.
Madurka I, Vishnevsky A, Soriano JB, Gans SJ, Ore DJS, Rendon A, Ulrik CS, Bhatnagar S, Krishnamurthy S, Mc Harry K, Welte T, Fernandez AA, Mehes B, Meiser K, Gatlik E, Sommer U, Junge G, Rezende E; Study group. Madurka I, et al. Infection. 2022 Sep 14:1-14. doi: 10.1007/s15010-022-01904-w. Online ahead of print. Infection. 2022. PMID: 36104613 Free PMC article.
A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein.
Zeller J, Cheung Tung Shing KS, Nero TL, McFadyen JD, Krippner G, Bogner B, Kreuzaler S, Kiefer J, Horner VK, Braig D, Danish H, Baratchi S, Fricke M, Wang X, Kather MG, Kammerer B, Woollard KJ, Sharma P, Morton CJ, Pietersz G, Parker MW, Peter K, Eisenhardt SU. Zeller J, et al. EMBO Mol Med. 2023 Jan 11;15(1):e16236. doi: 10.15252/emmm.202216236. Epub 2022 Dec 5. EMBO Mol Med. 2023. PMID: 36468184 Free PMC article.
C-reactive protein, immunothrombosis and venous thromboembolism.
Dix C, Zeller J, Stevens H, Eisenhardt SU, Shing KSCT, Nero TL, Morton CJ, Parker MW, Peter K, McFadyen JD. Dix C, et al. Among authors: zeller j. Front Immunol. 2022 Sep 13;13:1002652. doi: 10.3389/fimmu.2022.1002652. eCollection 2022. Front Immunol. 2022. PMID: 36177015 Free PMC article. Review.
Genotyping of Circulating Free DNA Enables Monitoring of Tumor Dynamics in Synovial Sarcomas.
Eisenhardt AE, Brugger Z, Lausch U, Kiefer J, Zeller J, Runkel A, Schmid A, Bronsert P, Wehrle J, Leithner A, Liegl-Atzwanger B, Giunta RE, Eisenhardt SU, Braig D. Eisenhardt AE, et al. Among authors: zeller j. Cancers (Basel). 2022 Apr 21;14(9):2078. doi: 10.3390/cancers14092078. Cancers (Basel). 2022. PMID: 35565213 Free PMC article.
Complicated Carotid Artery Plaques and Risk of Recurrent Ischemic Stroke or TIA.
Kopczak A, Schindler A, Sepp D, Bayer-Karpinska A, Malik R, Koch ML, Zeller J, Strecker C, Janowitz D, Wollenweber FA, Hempel JM, Boeckh-Behrens T, Cyran CC, Helck A, Harloff A, Ziemann U, Poli S, Poppert H, Saam T, Dichgans M. Kopczak A, et al. Among authors: zeller j. J Am Coll Cardiol. 2022 Jun 7;79(22):2189-2199. doi: 10.1016/j.jacc.2022.03.376. Epub 2022 May 3. J Am Coll Cardiol. 2022. PMID: 35523659 Free article.
Characterization of AAV-mediated dorsal root ganglionopathy.
Buss N, Lanigan L, Zeller J, Cissell D, Metea M, Adams E, Higgins M, Kim KH, Budzynski E, Yang L, Liu Y, Butt M, Danos O, Fiscella M. Buss N, et al. Among authors: zeller j. Mol Ther Methods Clin Dev. 2022 Feb 1;24:342-354. doi: 10.1016/j.omtm.2022.01.013. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2022. PMID: 35229008 Free PMC article.
Targeted next-generation sequencing of circulating free DNA enables non-invasive tumor detection in myxoid liposarcomas.
Eisenhardt AE, Schmid A, Esser J, Brugger Z, Lausch U, Kiefer J, Braig M, Runkel A, Wehrle J, Claus R, Bronsert P, Leithner A, Liegl-Atzwanger B, Zeller J, Papini R, von Laffert M, Pfitzner BM, Koulaxouzidis G, Giunta RE, Eisenhardt SU, Braig D. Eisenhardt AE, et al. Among authors: zeller j. Mol Cancer. 2022 Feb 14;21(1):50. doi: 10.1186/s12943-022-01523-x. Mol Cancer. 2022. PMID: 35164780 Free PMC article. No abstract available.
The bouba/kiki effect is robust across cultures and writing systems.
Ćwiek A, Fuchs S, Draxler C, Asu EL, Dediu D, Hiovain K, Kawahara S, Koutalidis S, Krifka M, Lippus P, Lupyan G, Oh GE, Paul J, Petrone C, Ridouane R, Reiter S, Schümchen N, Szalontai Á, Ünal-Logacev Ö, Zeller J, Perlman M, Winter B. Ćwiek A, et al. Among authors: zeller j. Philos Trans R Soc Lond B Biol Sci. 2022 Jan 3;377(1841):20200390. doi: 10.1098/rstb.2020.0390. Epub 2021 Nov 15. Philos Trans R Soc Lond B Biol Sci. 2022. PMID: 34775818 Free PMC article.
An Unbiased Flow Cytometry-Based Approach to Assess Subset-Specific Circulating Monocyte Activation and Cytokine Profile in Whole Blood.
Kiefer J, Zeller J, Bogner B, Hörbrand IA, Lang F, Deiss E, Winninger O, Fricke M, Kreuzaler S, Smudde E, Huber-Lang M, Peter K, Woollard KJ, Eisenhardt SU. Kiefer J, et al. Among authors: zeller j. Front Immunol. 2021 Apr 26;12:641224. doi: 10.3389/fimmu.2021.641224. eCollection 2021. Front Immunol. 2021. PMID: 33981302 Free PMC article.
Novel vocalizations are understood across cultures.
Ćwiek A, Fuchs S, Draxler C, Asu EL, Dediu D, Hiovain K, Kawahara S, Koutalidis S, Krifka M, Lippus P, Lupyan G, Oh GE, Paul J, Petrone C, Ridouane R, Reiter S, Schümchen N, Szalontai Á, Ünal-Logacev Ö, Zeller J, Winter B, Perlman M. Ćwiek A, et al. Among authors: zeller j. Sci Rep. 2021 May 12;11(1):10108. doi: 10.1038/s41598-021-89445-4. Sci Rep. 2021. PMID: 33980933 Free PMC article.
Local and systemic therapy of recurrent ependymoma in children and adolescents: short- and long-term results of the E-HIT-REZ 2005 study.
Adolph JE, Fleischhack G, Mikasch R, Zeller J, Warmuth-Metz M, Bison B, Mynarek M, Rutkowski S, Schüller U, von Hoff K, Obrecht D, Pietsch T, Pfister SM, Pajtler KW, Witt O, Witt H, Kortmann RD, Timmermann B, Krauß J, Frühwald MC, Faldum A, Kwiecien R, Bode U, Tippelt S. Adolph JE, et al. Among authors: zeller j. Neuro Oncol. 2021 Jun 1;23(6):1012-1023. doi: 10.1093/neuonc/noaa276. Neuro Oncol. 2021. PMID: 33331885 Free PMC article.
Complicated Carotid Artery Plaques as a Cause of Cryptogenic Stroke.
Kopczak A, Schindler A, Bayer-Karpinska A, Koch ML, Sepp D, Zeller J, Strecker C, Hempel JM, Yuan C, Malik R, Wollenweber FA, Boeckh-Behrens T, Cyran CC, Helck A, Harloff A, Ziemann U, Poli S, Poppert H, Dichgans M, Saam T. Kopczak A, et al. Among authors: zeller j. J Am Coll Cardiol. 2020 Nov 10;76(19):2212-2222. doi: 10.1016/j.jacc.2020.09.532. J Am Coll Cardiol. 2020. PMID: 33153580 Free article. Clinical Trial.
BNST and amygdala activation to threat: Effects of temporal predictability and threat mode.
Siminski N, Böhme S, Zeller JBM, Becker MPI, Bruchmann M, Hofmann D, Breuer F, Mühlberger A, Schiele MA, Weber H, Schartner C, Deckert J, Pauli P, Reif A, Domschke K, Straube T, Herrmann MJ. Siminski N, et al. Among authors: zeller jbm. Behav Brain Res. 2021 Jan 1;396:112883. doi: 10.1016/j.bbr.2020.112883. Epub 2020 Aug 26. Behav Brain Res. 2021. PMID: 32860830
The Ethical Triage and Management Guidelines of the Entrapped and Mangled Extremity in Resource Scarce Environments: A Systematic Literature Review.
Weinstein E, Gosney JE, Ragazzoni L, Franc J, Herbert T, Weinstein B, Verde M, Zeller J, Wolfson N, Boyce W, Cramer J. Weinstein E, et al. Among authors: zeller j. Disaster Med Public Health Prep. 2021 Jun;15(3):389-397. doi: 10.1017/dmp.2020.49. Epub 2020 May 27. Disaster Med Public Health Prep. 2021. PMID: 32456743
Phase 1 Human Immunodeficiency Virus (HIV) Vaccine Trial to Evaluate the Safety and Immunogenicity of HIV Subtype C DNA and MF59-Adjuvanted Subtype C Envelope Protein.
Hosseinipour MC, Innes C, Naidoo S, Mann P, Hutter J, Ramjee G, Sebe M, Maganga L, Herce ME, deCamp AC, Marshall K, Dintwe O, Andersen-Nissen E, Tomaras GD, Mkhize N, Morris L, Jensen R, Miner MD, Pantaleo G, Ding S, Van Der Meeren O, Barnett SW, McElrath MJ, Corey L, Kublin JG; HVTN 111 Protocol Team. Hosseinipour MC, et al. Clin Infect Dis. 2021 Jan 23;72(1):50-60. doi: 10.1093/cid/ciz1239. Clin Infect Dis. 2021. PMID: 31900486 Free PMC article. Clinical Trial.
Simulation-Based Training of the Rapid Evaluation and Management of Acute Stroke (STREAM)-A Prospective Single-Arm Multicenter Trial.
Bohmann FO, Kurka N, du Mesnil de Rochemont R, Gruber K, Guenther J, Rostek P, Rai H, Zickler P, Ertl M, Berlis A, Poli S, Mengel A, Ringleb P, Nagel S, Pfaff J, Wollenweber FA, Kellert L, Herzberg M, Koehler L, Haeusler KG, Alegiani A, Schubert C, Brekenfeld C, Doppler CEJ, Onur OA, Kabbasch C, Manser T, Pfeilschifter W; STREAM Trial Investigators. Bohmann FO, et al. Front Neurol. 2019 Sep 11;10:969. doi: 10.3389/fneur.2019.00969. eCollection 2019. Front Neurol. 2019. PMID: 31572288 Free PMC article.
Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion.
Brewer MK, Uittenbogaard A, Austin GL, Segvich DM, DePaoli-Roach A, Roach PJ, McCarthy JJ, Simmons ZR, Brandon JA, Zhou Z, Zeller J, Young LEA, Sun RC, Pauly JR, Aziz NM, Hodges BL, McKnight TR, Armstrong DD, Gentry MS. Brewer MK, et al. Among authors: zeller j. Cell Metab. 2019 Oct 1;30(4):689-705.e6. doi: 10.1016/j.cmet.2019.07.002. Epub 2019 Jul 25. Cell Metab. 2019. PMID: 31353261 Free PMC article.
Intracranial Hypertension and Cerebral Perfusion Pressure Insults in Adult Hypertensive Intraventricular Hemorrhage: Occurrence and Associations With Outcome.
Ziai WC, Thompson CB, Mayo S, McBee N, Freeman WD, Dlugash R, Ullman N, Hao Y, Lane K, Awad I, Hanley DF; Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III) Investigators. Ziai WC, et al. Crit Care Med. 2019 Aug;47(8):1125-1134. doi: 10.1097/CCM.0000000000003848. Crit Care Med. 2019. PMID: 31162192 Free PMC article. Clinical Trial.
Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level.
Lazarus SC, Krishnan JA, King TS, Lang JE, Blake KV, Covar R, Lugogo N, Wenzel S, Chinchilli VM, Mauger DT, Dyer AM, Boushey HA, Fahy JV, Woodruff PG, Bacharier LB, Cabana MD, Cardet JC, Castro M, Chmiel J, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Hastie A, Holguin F, Israel E, Jackson D, Kraft M, LaForce C, Lemanske RF Jr, Martinez FD, Moore W, Morgan WJ, Moy JN, Myers R, Peters SP, Phipatanakul W, Pongracic JA, Que L, Ross K, Smith L, Szefler SJ, Wechsler ME, Sorkness CA; National Heart, Lung, and Blood Institute AsthmaNet. Lazarus SC, et al. N Engl J Med. 2019 May 23;380(21):2009-2019. doi: 10.1056/NEJMoa1814917. Epub 2019 May 19. N Engl J Med. 2019. PMID: 31112384 Free PMC article. Clinical Trial.
A Conformational Change in C-Reactive Protein Enhances Leukocyte Recruitment and Reactive Oxygen Species Generation in Ischemia/Reperfusion Injury.
Thiele JR, Zeller J, Kiefer J, Braig D, Kreuzaler S, Lenz Y, Potempa LA, Grahammer F, Huber TB, Huber-Lang M, Bannasch H, Stark GB, Peter K, Eisenhardt SU. Thiele JR, et al. Among authors: zeller j. Front Immunol. 2018 Apr 16;9:675. doi: 10.3389/fimmu.2018.00675. eCollection 2018. Front Immunol. 2018. PMID: 29713320 Free PMC article.
Glutathione and arginine levels: Predictors for acetaminophen-associated asthma exacerbation?
Morris CR, Mauger DT, Suh JH, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Szefler SJ, Jackson DJ, Fitzpatrick AM; National Institutes of Health/National Heart, Lung, and Blood Institute AsthmaNet. Morris CR, et al. J Allergy Clin Immunol. 2018 Jul;142(1):308-311.e9. doi: 10.1016/j.jaci.2018.01.045. Epub 2018 Mar 5. J Allergy Clin Immunol. 2018. PMID: 29518418 Free PMC article. Clinical Trial. No abstract available.
Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.
Schofield HK, Zeller J, Espinoza C, Halbrook CJ, Del Vecchio A, Magnuson B, Fabo T, Cali Daylan AE, Kovalenko I, Lee HJ, Yan W, Feng Y, Karim SA, Kremer DM, Kumar-Sinha C, Lyssiotis CA, Ljungman M, Morton JP, Galbán S, Fearon ER, Pasca di Magliano M. Schofield HK, et al. Among authors: zeller j. JCI Insight. 2018 Jan 25;3(2):e97422. doi: 10.1172/jci.insight.97422. eCollection 2018 Jan 25. JCI Insight. 2018. PMID: 29367463 Free PMC article.
Near-infrared spectroscopy (NIRS) and vagus somatosensory evoked potentials (VSEP) in the early diagnosis of Alzheimer's disease: rationale, design, methods, and first baseline data of the Vogel study.
Polak T, Herrmann MJ, Müller LD, Zeller JBM, Katzorke A, Fischer M, Spielmann F, Weinmann E, Hommers L, Lauer M, Fallgatter AJ, Deckert J. Polak T, et al. Among authors: zeller jbm. J Neural Transm (Vienna). 2017 Nov;124(11):1473-1488. doi: 10.1007/s00702-017-1781-0. Epub 2017 Sep 1. J Neural Transm (Vienna). 2017. PMID: 28864837
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites.
Braig D, Nero TL, Koch HG, Kaiser B, Wang X, Thiele JR, Morton CJ, Zeller J, Kiefer J, Potempa LA, Mellett NA, Miles LA, Du XJ, Meikle PJ, Huber-Lang M, Stark GB, Parker MW, Peter K, Eisenhardt SU. Braig D, et al. Among authors: zeller j. Nat Commun. 2017 Jan 23;8:14188. doi: 10.1038/ncomms14188. Nat Commun. 2017. PMID: 28112148 Free PMC article.
Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma.
Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W; NIH/NHLBI AsthmaNet. Sheehan WJ, et al. N Engl J Med. 2016 Aug 18;375(7):619-30. doi: 10.1056/NEJMoa1515990. N Engl J Med. 2016. PMID: 27532828 Free PMC article. Clinical Trial.
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
Qureshi AI, Palesch YY, Barsan WG, Hanley DF, Hsu CY, Martin RL, Moy CS, Silbergleit R, Steiner T, Suarez JI, Toyoda K, Wang Y, Yamamoto H, Yoon BW; ATACH-2 Trial Investigators and the Neurological Emergency Treatment Trials Network. Qureshi AI, et al. N Engl J Med. 2016 Sep 15;375(11):1033-43. doi: 10.1056/NEJMoa1603460. Epub 2016 Jun 8. N Engl J Med. 2016. PMID: 27276234 Free PMC article. Clinical Trial.
JAMA patient page. Pulmonary hypertension.
Zeller JL, Goodman DM, Lynm C, Livingston EH. Zeller JL, et al. JAMA. 2012 Oct 3;308(13):1390. doi: 10.1001/2012.jama.11701. JAMA. 2012. PMID: 23032558 No abstract available.
Role of noncoding RNA ANRIL in genesis of plexiform neurofibromas in neurofibromatosis type 1.
Pasmant E, Sabbagh A, Masliah-Planchon J, Ortonne N, Laurendeau I, Melin L, Ferkal S, Hernandez L, Leroy K, Valeyrie-Allanore L, Parfait B, Vidaud D, Bièche I, Lantieri L, Wolkenstein P, Vidaud M; NF France Network. Pasmant E, et al. J Natl Cancer Inst. 2011 Nov 16;103(22):1713-22. doi: 10.1093/jnci/djr416. Epub 2011 Oct 27. J Natl Cancer Inst. 2011. PMID: 22034633
JAMA patient page. MRSA infections.
Zeller JL, Golub RM. Zeller JL, et al. JAMA. 2011 Oct 26;306(16):1818. doi: 10.1001/jama.306.16.1818. JAMA. 2011. PMID: 22028359 No abstract available.
At-risk phenotype of neurofibromatose-1 patients: a multicentre case-control study.
Sbidian E, Bastuji-Garin S, Valeyrie-Allanore L, Ferkal S, Lefaucheur JP, Drouet A, Brugière P, Vialette C, Combemale P, Barbarot S, Wolkenstein P; NF France Network. Sbidian E, et al. Orphanet J Rare Dis. 2011 Jul 13;6:51. doi: 10.1186/1750-1172-6-51. Orphanet J Rare Dis. 2011. PMID: 21752287 Free PMC article.
361 results