Prots I - Search Results

1

Axon-Specific Mitochondrial Pathology in SPG11 Alpha Motor Neurons.

Güner F, Pozner T, Krach F, Prots I, Loskarn S, Schlötzer-Schrehardt U, Winkler J, Winner B, Regensburger M. Güner F, et al. Among authors: prots i. Front Neurosci. 2021 Jul 7;15:680572. doi: 10.3389/fnins.2021.680572. eCollection 2021. Front Neurosci. 2021. PMID: 34326717 Free PMC article.

2

Adult hippocampal neurogenesis in Parkinson's disease: impact on neuronal survival and plasticity.

Regensburger M, Prots I, Winner B. Regensburger M, et al. Among authors: prots i. Neural Plast. 2014;2014:454696. doi: 10.1155/2014/454696. Epub 2014 Jul 3. Neural Plast. 2014. PMID: 25110593 Free PMC article. Review.

3

α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies.

Prots I, Grosch J, Brazdis RM, Simmnacher K, Veber V, Havlicek S, Hannappel C, Krach F, Krumbiegel M, Schütz O, Reis A, Wrasidlo W, Galasko DR, Groemer TW, Masliah E, Schlötzer-Schrehardt U, Xiang W, Winkler J, Winner B. Prots I, et al. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7813-7818. doi: 10.1073/pnas.1713129115. Epub 2018 Jul 10. Proc Natl Acad Sci U S A. 2018. PMID: 29991596 Free PMC article.

4

The Quest for Anti-α-Synuclein Antibody Specificity-Lessons Learnt From Flow Cytometry Analysis.

Leupold L, Sigutova V, Gerasimova E, Regensburger M, Zundler S, Zunke F, Xiang W, Winner B, Prots I. Leupold L, et al. Among authors: prots i. Front Neurol. 2022 Jul 15;13:869103. doi: 10.3389/fneur.2022.869103. eCollection 2022. Front Neurol. 2022. PMID: 35911883 Free PMC article.

5

Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia.

Pérez-Brangulí F, Mishra HK, Prots I, Havlicek S, Kohl Z, Saul D, Rummel C, Dorca-Arevalo J, Regensburger M, Graef D, Sock E, Blasi J, Groemer TW, Schlötzer-Schrehardt U, Winkler J, Winner B. Pérez-Brangulí F, et al. Among authors: prots i. Hum Mol Genet. 2014 Sep 15;23(18):4859-74. doi: 10.1093/hmg/ddu200. Epub 2014 May 2. Hum Mol Genet. 2014. PMID: 24794856 Free PMC article.

6

GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient induced pluripotent stem cell model.

Mishra HK, Prots I, Havlicek S, Kohl Z, Perez-Branguli F, Boerstler T, Anneser L, Minakaki G, Wend H, Hampl M, Leone M, Brückner M, Klucken J, Reis A, Boyer L, Schuierer G, Behrens J, Lampert A, Engel FB, Gage FH, Winkler J, Winner B. Mishra HK, et al. Among authors: prots i. Ann Neurol. 2016 May;79(5):826-840. doi: 10.1002/ana.24633. Ann Neurol. 2016. PMID: 26971897 Free PMC article.

7

Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress.

Menges S, Minakaki G, Schaefer PM, Meixner H, Prots I, Schlötzer-Schrehardt U, Friedland K, Winner B, Outeiro TF, Winklhofer KF, von Arnim CA, Xiang W, Winkler J, Klucken J. Menges S, et al. Among authors: prots i. Sci Rep. 2017 Feb 22;7:42942. doi: 10.1038/srep42942. Sci Rep. 2017. PMID: 28224980 Free PMC article.

8

The Trojan horse - neuroinflammatory impact of T cells in neurodegenerative diseases.

Sommer A, Winner B, Prots I. Sommer A, et al. Among authors: prots i. Mol Neurodegener. 2017 Oct 27;12(1):78. doi: 10.1186/s13024-017-0222-8. Mol Neurodegener. 2017. PMID: 29078813 Free PMC article. Review.

9

Impact of Swiprosin-1/Efhd2 on Adult Hippocampal Neurogenesis.

Regensburger M, Prots I, Reimer D, Brachs S, Loskarn S, Lie DC, Mielenz D, Winner B. Regensburger M, et al. Among authors: prots i. Stem Cell Reports. 2018 Feb 13;10(2):347-355. doi: 10.1016/j.stemcr.2017.12.010. Epub 2018 Jan 11. Stem Cell Reports. 2018. PMID: 29337116 Free PMC article.

10

Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease.

Sommer A, Marxreiter F, Krach F, Fadler T, Grosch J, Maroni M, Graef D, Eberhardt E, Riemenschneider MJ, Yeo GW, Kohl Z, Xiang W, Gage FH, Winkler J, Prots I, Winner B. Sommer A, et al. Among authors: prots i. Cell Stem Cell. 2018 Jul 5;23(1):123-131.e6. doi: 10.1016/j.stem.2018.06.015. Cell Stem Cell. 2018. PMID: 29979986 Free article.

11

Interaction of Alpha Synuclein and Microtubule Organization Is Linked to Impaired Neuritic Integrity in Parkinson's Patient-Derived Neuronal Cells.

Seebauer L, Schneider Y, Drobny A, Plötz S, Koudelka T, Tholey A, Prots I, Winner B, Zunke F, Winkler J, Xiang W. Seebauer L, et al. Among authors: prots i. Int J Mol Sci. 2022 Feb 5;23(3):1812. doi: 10.3390/ijms23031812. Int J Mol Sci. 2022. PMID: 35163733 Free PMC article.

12

Th17 cells: a promising therapeutic target for Parkinson's disease?

Prots I, Winner B. Prots I, et al. Expert Opin Ther Targets. 2019 Apr;23(4):309-314. doi: 10.1080/14728222.2019.1590336. Epub 2019 Mar 14. Expert Opin Ther Targets. 2019. PMID: 30871383 Review.

13

Translocation of Distinct Alpha Synuclein Species from the Nucleus to Neuronal Processes during Neuronal Differentiation.

Pieger K, Schmitt V, Gauer C, Gießl N, Prots I, Winner B, Winkler J, Brandstätter JH, Xiang W. Pieger K, et al. Among authors: prots i. Biomolecules. 2022 Aug 12;12(8):1108. doi: 10.3390/biom12081108. Biomolecules. 2022. PMID: 36009004 Free PMC article.

14

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons.

Havlicek S, Kohl Z, Mishra HK, Prots I, Eberhardt E, Denguir N, Wend H, Plötz S, Boyer L, Marchetto MC, Aigner S, Sticht H, Groemer TW, Hehr U, Lampert A, Schlötzer-Schrehardt U, Winkler J, Gage FH, Winner B. Havlicek S, et al. Among authors: prots i. Hum Mol Genet. 2014 May 15;23(10):2527-41. doi: 10.1093/hmg/ddt644. Epub 2013 Dec 30. Hum Mol Genet. 2014. PMID: 24381312 Free PMC article.

15

Unique signatures of stress-induced senescent human astrocytes.

Simmnacher K, Krach F, Schneider Y, Alecu JE, Mautner L, Klein P, Roybon L, Prots I, Xiang W, Winner B. Simmnacher K, et al. Among authors: prots i. Exp Neurol. 2020 Dec;334:113466. doi: 10.1016/j.expneurol.2020.113466. Epub 2020 Sep 17. Exp Neurol. 2020. PMID: 32949572 Free article.

16

The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons.

Purohit P, Perez-Branguli F, Prots I, Borger E, Gunn-Moore F, Welzel O, Loy K, Wenzel EM, Grömer TW, Brachs S, Holzer M, Buslei R, Fritsch K, Regensburger M, Böhm KJ, Winner B, Mielenz D. Purohit P, et al. Among authors: prots i. PLoS One. 2014 Aug 18;9(8):e103976. doi: 10.1371/journal.pone.0103976. eCollection 2014. PLoS One. 2014. PMID: 25133820 Free PMC article.

17

A monocyte gene expression signature in the early clinical course of Parkinson's disease.

Schlachetzki JCM, Prots I, Tao J, Chun HB, Saijo K, Gosselin D, Winner B, Glass CK, Winkler J. Schlachetzki JCM, et al. Among authors: prots i. Sci Rep. 2018 Jul 17;8(1):10757. doi: 10.1038/s41598-018-28986-7. Sci Rep. 2018. PMID: 30018301 Free PMC article.

18

Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease.

Brazdis RM, Alecu JE, Marsch D, Dahms A, Simmnacher K, Lörentz S, Brendler A, Schneider Y, Marxreiter F, Roybon L, Winner B, Xiang W, Prots I. Brazdis RM, et al. Among authors: prots i. Hum Mol Genet. 2020 May 8;29(7):1180-1191. doi: 10.1093/hmg/ddaa039. Hum Mol Genet. 2020. PMID: 32160287 Free PMC article.

19

Author Correction: A monocyte gene expression signature in the early clinical course of Parkinson's disease.

Schlachetzki JCM, Prots I, Tao J, Chun HB, Saijo K, Gosselin D, Winner B, Glass CK, Winkler J. Schlachetzki JCM, et al. Among authors: prots i. Sci Rep. 2020 Apr 7;10(1):6261. doi: 10.1038/s41598-020-62928-6. Sci Rep. 2020. PMID: 32253373 Free PMC article.

20

Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus.

Winner B, Regensburger M, Schreglmann S, Boyer L, Prots I, Rockenstein E, Mante M, Zhao C, Winkler J, Masliah E, Gage FH. Winner B, et al. Among authors: prots i. J Neurosci. 2012 Nov 21;32(47):16906-16. doi: 10.1523/JNEUROSCI.2723-12.2012. J Neurosci. 2012. PMID: 23175842 Free PMC article.

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