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Projecting the impact of triple CFTR modulator therapy on intravenous antibiotic requirements in cystic fibrosis using patient registry data combined with treatment effects from randomised trials.
Keogh RH, Cosgriff R, Andrinopoulou ER, Brownlee KG, Carr SB, Diaz-Ordaz K, Granger E, Jewell NP, Lewin A, Leyrat C, Schlüter DK, van Smeden M, Szczesniak RD, Connett GJ. Keogh RH, et al. Among authors: carr sb. Thorax. 2022 Sep;77(9):873-881. doi: 10.1136/thoraxjnl-2020-216265. Epub 2021 Sep 23. Thorax. 2022. PMID: 34556554 Free PMC article.
Lung function is abnormal in 3-month-old infants with cystic fibrosis diagnosed by newborn screening.
Hoo AF, Thia LP, Nguyen TT, Bush A, Chudleigh J, Lum S, Ahmed D, Balfour Lynn I, Carr SB, Chavasse RJ, Costeloe KL, Price J, Shankar A, Wallis C, Wyatt HA, Wade A, Stocks J; London Cystic Fibrosis Collaboration. Hoo AF, et al. Among authors: carr sb. Thorax. 2012 Oct;67(10):874-81. doi: 10.1136/thoraxjnl-2012-201747. Epub 2012 Jun 29. Thorax. 2012. PMID: 22752198
Data Resource Profile: The UK Cystic Fibrosis Registry.
Taylor-Robinson D, Archangelidi O, Carr SB, Cosgriff R, Gunn E, Keogh RH, MacDougall A, Newsome S, Schlüter DK, Stanojevic S, Bilton D; CF-EpinNet collaboration. Taylor-Robinson D, et al. Among authors: carr sb. Int J Epidemiol. 2018 Feb 1;47(1):9-10e. doi: 10.1093/ije/dyx196. Int J Epidemiol. 2018. PMID: 29040601 Free PMC article. No abstract available.
Fair selection of participants in clinical trials: The challenge to push the envelope further.
Davies JC, Scott S, Dobra R, Brendell R, Brownlee K, Carr SB, Cosgriff R, Simmonds NJ; London Network of Clinical Trials Accelerator Platform sites; Jahan R, Jones A, Matthews J, Brown S, Galono K, Miles K, Pao C, Shafi N, Watson D, Orchard C, Davies G, Pike K, Shah S, Bossley CJ, Fong T, Macedo P, Ruiz G, Waller M, Baker L. Davies JC, et al. Among authors: carr sb. J Cyst Fibros. 2019 Sep;18(5):e48-e50. doi: 10.1016/j.jcf.2019.07.004. Epub 2019 Aug 9. J Cyst Fibros. 2019. PMID: 31405729 Free article. No abstract available.
Changing epidemiology of the respiratory bacteriology of patients with cystic fibrosis-data from the European cystic fibrosis society patient registry.
Hatziagorou E, Orenti A, Drevinek P, Kashirskaya N, Mei-Zahav M, De Boeck K; ECFSPR. Electronic address: ECFS-Patient.Registry@uz.kuleuven.ac.be; ECFSPR. Hatziagorou E, et al. J Cyst Fibros. 2020 May;19(3):376-383. doi: 10.1016/j.jcf.2019.08.006. Epub 2019 Sep 3. J Cyst Fibros. 2020. PMID: 31492646 Free article.
A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis.
Cosgriff R, Ahern S, Bell SC, Brownlee K, Burgel PR, Byrnes C, Corvol H, Cheng SY, Elbert A, Faro A, Goss CH, Gulmans V, Marshall BC, McKone E, Middleton PG, Ruseckaite R, Stephenson AL, Carr SB; Global Registry Harmonization Group. Cosgriff R, et al. Among authors: carr sb. J Cyst Fibros. 2020 May;19(3):355-358. doi: 10.1016/j.jcf.2020.04.012. Epub 2020 Apr 25. J Cyst Fibros. 2020. PMID: 32376098 Free PMC article.
The global impact of SARS-CoV-2 in 181 people with cystic fibrosis.
McClenaghan E, Cosgriff R, Brownlee K, Ahern S, Burgel PR, Byrnes CA, Colombo C, Corvol H, Cheng SY, Daneau G, Elbert A, Faro A, Goss CH, Gulmans V, Gutierrez H, de Monestrol I, Jung A, Justus LN, Kashirskaya N, Marshall BC, McKone E, Middleton PG, Mondejar-Lopez P, Pastor-Vivero MD, Padoan R, Rizvi S, Ruseckaite R, Salvatore M, Stephenson AL, Filho LVRDS, Melo J, Zampoli M, Carr SB; Global Registry Harmonization Group. McClenaghan E, et al. Among authors: carr sb. J Cyst Fibros. 2020 Nov;19(6):868-871. doi: 10.1016/j.jcf.2020.10.003. Epub 2020 Nov 4. J Cyst Fibros. 2020. PMID: 33183965 Free PMC article.
Clinical characteristics of SARS-CoV-2 infection in children with cystic fibrosis: An international observational study.
Bain R, Cosgriff R, Zampoli M, Elbert A, Burgel PR, Carr SB, Castaños C, Colombo C, Corvol H, Faro A, Goss CH, Gutierrez H, Jung A, Kashirskaya N, Marshall BC, Melo J, Mondejar-Lopez P, de Monestrol I, Naehrlich L, Padoan R, Pastor-Vivero MD, Rizvi S, Salvatore M, Filho LVRFDS, Brownlee KG, Haq IJ, Brodlie M. Bain R, et al. Among authors: carr sb. J Cyst Fibros. 2021 Jan;20(1):25-30. doi: 10.1016/j.jcf.2020.11.021. Epub 2020 Dec 3. J Cyst Fibros. 2021. PMID: 33309057 Free PMC article.
Survival estimates in European cystic fibrosis patients and the impact of socioeconomic factors: a retrospective registry cohort study.
McKone EF, Ariti C, Jackson A, Zolin A, Carr SB, Orenti A, van Rens JG, Lemonnier L, Macek M Jr, Keogh RH, Naehrlich L; European Cystic Fibrosis Society Patient Registry; ECFSPR contributors list consists of the representatives of the countries whose data is used in this article, and the members of the Scientific Committee who reviewed the initial data application and the final manuscript. Collaborating authors:. McKone EF, et al. Among authors: carr sb. Eur Respir J. 2021 Oct 1;58(3):2002288. doi: 10.1183/13993003.02288-2020. Print 2021 Sep. Eur Respir J. 2021. PMID: 33678607 Free article.
Optimising equity of access: how should we allocate slots to the most competitive trials in Cystic Fibrosis (CF)?
Dobra R, Davies G, Pike K, Strassle C, Allen L, Brendell R, Brownlee K, Carr SB, Simmonds NJ, Davies JC; London Network of Clinical Trials Accelerator Platform sites and affiliates. Dobra R, et al. Among authors: carr sb. J Cyst Fibros. 2021 Nov;20(6):978-985. doi: 10.1016/j.jcf.2021.03.027. Epub 2021 Apr 17. J Cyst Fibros. 2021. PMID: 33875366 Free article.
COVID-19 vaccine prioritisation for people with cystic fibrosis.
Carr SB, Cosgriff R, Harutyunyan S, Middleton PG, Ruseckaite R, Ahern S, Daneau G, Filho LVRFDS, Stephenson AL, Cheng SY, Melo J, Corvol H, Burgel PR, Nährlich L, McKone E, Colombo C, Salvatore M, Padoan R, Abdrakhmanov O, Gulmans V, Byrnes CA, Amelina E, Kondratyeva E, Zhekayte E, Kashirskaya N, Zampoli M, Pastor-Vivero MD, Mondejar-Lopez P, de Monestrol I, Jung A, McClenaghan E, Brownlee K, Rizvi S, Goss CH, Elbert A, Faro A, Gutierrez H, Marshall BC. Carr SB, et al. J Cyst Fibros. 2021 Jul;20(4):715-716. doi: 10.1016/j.jcf.2021.03.028. Epub 2021 Apr 15. J Cyst Fibros. 2021. PMID: 33941502 Free PMC article. No abstract available.
Incidence of SARS-CoV-2 in people with cystic fibrosis in Europe between February and June 2020.
Naehrlich L, Orenti A, Dunlevy F, Kasmi I, Harutyunyan S, Pfleger A, Keegan S, Daneau G, Petrova G, Tješić-Drinković D, Yiallouros P, Bilkova A, Olesen HV, Burgel PR, Parulava T, Diamantea F, Párniczky A, McKone EF, Mei-Zahav M, Salvatore M, Colombo C, Aleksejeva E, Malakauskas K, Schlesser M, Fustik S, Turcu O, Zomer-van Ommen D, Wathne AS, Woźniacki Ł, Pereira L, Pop L, Kashirskaya N, Rodić M, Kayserova H, Krivecs U, Mondejar-Lopez P, de Monestrol I, Dogru D, Makukh H, Cosgriff R, van Koningsbruggen-Rietschel S, Jung A; European Cystic Fibrosis COVID project group. Naehrlich L, et al. J Cyst Fibros. 2021 Jul;20(4):566-577. doi: 10.1016/j.jcf.2021.03.017. Epub 2021 Apr 18. J Cyst Fibros. 2021. PMID: 34016559 Free PMC article.
Factors for severe outcomes following SARS-CoV-2 infection in people with cystic fibrosis in Europe.
Jung A, Orenti A, Dunlevy F, Aleksejeva E, Bakkeheim E, Bobrovnichy V, Carr SB, Colombo C, Corvol H, Cosgriff R, Daneau G, Dogru D, Drevinek P, Vukic AD, Fajac I, Fox A, Fustik S, Gulmans V, Harutyunyan S, Hatziagorou E, Kasmi I, Kayserová H, Kondratyeva E, Krivec U, Makukh H, Malakauskas K, McKone EF, Mei-Zahav M, de Monestrol I, Olesen HV, Padoan R, Parulava T, Pastor-Vivero MD, Pereira L, Petrova G, Pfleger A, Pop L, van Rens JG, Rodic M, Schlesser M, Storms V, Turcu O, Woz Niacki L, Yiallouros P, Zolin A, Downey DG, Naehrlich L. Jung A, et al. Among authors: carr sb. ERJ Open Res. 2021 Dec 27;7(4):00411-2021. doi: 10.1183/23120541.00411-2021. eCollection 2021 Oct. ERJ Open Res. 2021. PMID: 34984210 Free PMC article.
Factors associated with clinical progression to severe COVID-19 in people with cystic fibrosis: A global observational study.
Carr SB, McClenaghan E, Elbert A, Faro A, Cosgriff R, Abdrakhmanov O, Brownlee K, Burgel PR, Byrnes CA, Cheng SY, Colombo C, Corvol H, Daneau G, Goss CH, Gulmans V, Gutierrez H, Harutyunyan S, Helmick M, Jung A, Kashirskaya N, McKone E, Melo J, Middleton PG, Mondejar-Lopez P, de Monestrol I, Nährlich L, Padoan R, Parker M, Pastor-Vivero MD, Rizvi S, Ruseckaite R, Salvatore M, da Silva-Filho LVRF, Versmessen N, Zampoli M, Marshall BC, Stephenson AL; CF Registry Global Collaboration. Carr SB, et al. J Cyst Fibros. 2022 Jul;21(4):e221-e231. doi: 10.1016/j.jcf.2022.06.006. Epub 2022 Jun 13. J Cyst Fibros. 2022. PMID: 35753987 Free PMC article.
Growth and lung function in Asian patients with cystic fibrosis.
Callaghan BD, Hoo AF, Dinwiddie R, Balfour-Lynn IM, Carr SB. Callaghan BD, et al. Among authors: carr sb. Arch Dis Child. 2005 Oct;90(10):1029-32. doi: 10.1136/adc.2004.067264. Arch Dis Child. 2005. PMID: 16177157 Free PMC article.
Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests.
Lum S, Gustafsson P, Ljungberg H, Hülskamp G, Bush A, Carr SB, Castle R, Hoo AF, Price J, Ranganathan S, Stroobant J, Wade A, Wallis C, Wyatt H, Stocks J; London Cystic Fibrosis Collaboration. Lum S, et al. Among authors: carr sb. Thorax. 2007 Apr;62(4):341-7. doi: 10.1136/thx.2006.068262. Epub 2006 Nov 22. Thorax. 2007. PMID: 17121870 Free PMC article.
Growth in children with cystic fibrosis-related diabetes.
Cheung MS, Bridges NA, Prasad SA, Francis J, Carr SB, Suri R, Balfour-Lynn IM. Cheung MS, et al. Among authors: carr sb. Pediatr Pulmonol. 2009 Dec;44(12):1223-5. doi: 10.1002/ppul.21127. Pediatr Pulmonol. 2009. PMID: 19894249
High prevalence of CCDC103 p.His154Pro mutation causing primary ciliary dyskinesia disrupts protein oligomerisation and is associated with normal diagnostic investigations.
Shoemark A, Moya E, Hirst RA, Patel MP, Robson EA, Hayward J, Scully J, Fassad MR, Lamb W, Schmidts M, Dixon M, Patel-King RS, Rogers AV, Rutman A, Jackson CL, Goggin P, Rubbo B, Ollosson S, Carr S, Walker W, Adler B, Loebinger MR, Wilson R, Bush A, Williams H, Boustred C, Jenkins L, Sheridan E, Chung EMK, Watson CM, Cullup T, Lucas JS, Kenia P, O'Callaghan C, King SM, Hogg C, Mitchison HM. Shoemark A, et al. Thorax. 2018 Feb;73(2):157-166. doi: 10.1136/thoraxjnl-2017-209999. Epub 2017 Aug 8. Thorax. 2018. PMID: 28790179 Free PMC article.
Pulmonary function deficits in newborn screened infants with cystic fibrosis managed with standard UK care are mild and transient.
Davies G, Stocks J, Thia LP, Hoo AF, Bush A, Aurora P, Brennan L, Lee S, Lum S, Cottam P, Miles J, Chudleigh J, Kirkby J, Balfour-Lynn IM, Carr SB, Wallis C, Wyatt H, Wade A; London Cystic Fibrosis Collaboration (LCFC). Davies G, et al. Among authors: carr sb. Eur Respir J. 2017 Nov 9;50(5):1700326. doi: 10.1183/13993003.00326-2017. Print 2017 Nov. Eur Respir J. 2017. PMID: 29122914 Free article.
Health economic modelling in Cystic Fibrosis: A systematic review.
Mohindru B, Turner D, Sach T, Bilton D, Carr S, Archangelidi O, Bhadhuri A, Whitty JA. Mohindru B, et al. J Cyst Fibros. 2019 Jul;18(4):452-460. doi: 10.1016/j.jcf.2019.01.007. Epub 2019 Feb 7. J Cyst Fibros. 2019. PMID: 30738801 Free article.
Minimal change in structural, functional and inflammatory markers of lung disease in newborn screened infants with cystic fibrosis at one year.
Davies G, Thia LP, Stocks J, Bush A, Hoo AF, Wade A, Nguyen TTD, Brody AS, Calder A, Klein NJ, Carr SB, Wallis C, Suri R, Pao CS, Ruiz G, Balfour-Lynn IM; London Cystic Fibrosis Collaboration (LCFC). Davies G, et al. Among authors: carr sb. J Cyst Fibros. 2020 Nov;19(6):896-901. doi: 10.1016/j.jcf.2020.01.006. Epub 2020 Feb 7. J Cyst Fibros. 2020. PMID: 32044244 Free article.
Clinical features and management of children with primary ciliary dyskinesia in England.
Rubbo B, Best S, Hirst RA, Shoemark A, Goggin P, Carr SB, Chetcuti P, Hogg C, Kenia P, Lucas JS, Moya E, Narayanan M, O'Callaghan C, Williamson M, Walker WT; English National Children’s PCD Management Service. Rubbo B, et al. Among authors: carr sb. Arch Dis Child. 2020 Aug;105(8):724-729. doi: 10.1136/archdischild-2019-317687. Epub 2020 Mar 10. Arch Dis Child. 2020. PMID: 32156696
An observational study of the lung clearance index throughout childhood in cystic fibrosis: early years matter.
Davies G, Stanojevic S, Raywood E, Duncan JA, Stocks J, Lum S, Bush A, Viviani L, Wade A, Calder A, Owens CM, Goubau C, Carr SB, Bossley CJ, Pao C, Aurora P; London Cystic Fibrosis Collaboration. Davies G, et al. Among authors: carr sb. Eur Respir J. 2020 Oct 1;56(4):2000006. doi: 10.1183/13993003.00006-2020. Print 2020 Oct. Eur Respir J. 2020. PMID: 32444409 Free PMC article.
Future therapies for cystic fibrosis.
Allen L, Allen L, Carr SB, Davies G, Downey D, Egan M, Forton JT, Gray R, Haworth C, Horsley A, Smyth AR, Southern KW, Davies JC. Allen L, et al. Among authors: carr sb. Nat Commun. 2023 Feb 8;14(1):693. doi: 10.1038/s41467-023-36244-2. Nat Commun. 2023. PMID: 36755044 Free PMC article. Review.
An evaluation of two aerosol delivery systems for rhDNase.
Shah PL, Scott SF, Geddes DM, Conway S, Watson A, Nazir T, Carr SB, Wallis C, Marriott C, Hodson ME. Shah PL, et al. Among authors: carr sb. Eur Respir J. 1997 Jun;10(6):1261-6. doi: 10.1183/09031936.97.10061261. Eur Respir J. 1997. PMID: 9192926 Free article. Clinical Trial.
ECFS standards of care on CFTR-related disorders: Towards a comprehensive program for affected individuals.
De Wachter E, De Boeck K, Sermet-Gaudelus I, Simmonds NJ, Munck A, Naehrlich L, Barben J, Boyd C, Veen SJ, Carr SB, Fajac I, Farrell PM, Girodon E, Gonska T, Grody WW, Jain M, Jung A, Kerem E, Raraigh KS, van Koningsbruggen-Rietschel S, Waller MD, Southern KW, Castellani C; ECFS Diagnostic Network Working Group. De Wachter E, et al. Among authors: carr sb. J Cyst Fibros. 2024 Feb 21:S1569-1993(24)00011-0. doi: 10.1016/j.jcf.2024.01.012. Online ahead of print. J Cyst Fibros. 2024. PMID: 38388234
Health State Utility Data in Cystic Fibrosis: A Systematic Review.
Mohindru B, Turner D, Sach T, Bilton D, Carr S, Archangelidi O, Bhadhuri A, Whitty JA. Mohindru B, et al. Pharmacoecon Open. 2020 Mar;4(1):13-25. doi: 10.1007/s41669-019-0144-1. Pharmacoecon Open. 2020. PMID: 31054048 Free PMC article. Review.
Topological data analysis reveals genotype-phenotype relationships in primary ciliary dyskinesia.
Shoemark A, Rubbo B, Legendre M, Fassad MR, Haarman EG, Best S, Bon ICM, Brandsma J, Burgel PR, Carlsson G, Carr SB, Carroll M, Edwards M, Escudier E, Honoré I, Hunt D, Jouvion G, Loebinger MR, Maitre B, Morris-Rosendahl D, Papon JF, Parsons CM, Patel MP, Thomas NS, Thouvenin G, Walker WT, Wilson R, Hogg C, Mitchison HM, Lucas JS. Shoemark A, et al. Among authors: carr sb. Eur Respir J. 2021 Aug 5;58(2):2002359. doi: 10.1183/13993003.02359-2020. Print 2021 Aug. Eur Respir J. 2021. PMID: 33479112 Free article.
The disease-specific clinical trial network for primary ciliary dyskinesia: PCD-CTN.
Raidt J, Maitre B, Pennekamp P, Altenburg J, Anagnostopoulou P, Armengot M, Bloemsma LD, Boon M, Borrelli M, Brinkmann F, Carr SB, Carroll MP, Castillo-Corullón S, Coste A, Cutrera R, Dehlink E, Destouches DMS, Di Cicco ME, Dixon L, Emiralioglu N, Erdem Eralp E, Haarman EG, Hogg C, Karadag B, Kobbernagel HE, Lorent N, Mall MA, Marthin JK, Martinu V, Narayanan M, Ozcelik U, Peckham D, Pifferi M, Pohunek P, Polverino E, Range S, Ringshausen FC, Robson E, Roehmel J, Rovira-Amigo S, Santamaria F, Schlegtendal A, Szépfalusi Z, Tempels P, Thouvenin G, Ullmann N, Walker WT, Wetzke M, Yiallouros P, Omran H, Nielsen KG. Raidt J, et al. Among authors: carr sb. ERJ Open Res. 2022 Aug 15;8(3):00139-2022. doi: 10.1183/23120541.00139-2022. eCollection 2022 Jul. ERJ Open Res. 2022. PMID: 35983540 Free PMC article.
Lung function from infancy to the preschool years after clinical diagnosis of cystic fibrosis.
Kozlowska WJ, Bush A, Wade A, Aurora P, Carr SB, Castle RA, Hoo AF, Lum S, Price J, Ranganathan S, Saunders C, Stanojevic S, Stroobant J, Wallis C, Stocks J; London Cystic Fibrosis Collaboration. Kozlowska WJ, et al. Among authors: carr sb. Am J Respir Crit Care Med. 2008 Jul 1;178(1):42-9. doi: 10.1164/rccm.200710-1599OC. Epub 2008 Apr 10. Am J Respir Crit Care Med. 2008. PMID: 18403721
Pulmonary exacerbations in patients with primary ciliary dyskinesia: an expert consensus definition for use in clinical trials.
Lucas JS, Gahleitner F, Amorim A, Boon M, Brown P, Constant C, Cook S, Crowley S, Destouches DMS, Eber E, Mussaffi H, Haarman E, Harris A, Koerner-Rettberg C, Kuehni CE, Latzin P, Loebinger MR, Lorent N, Maitre B, Moreno-Galdó A, Nielsen KG, Özçelik U, Philipsen LKD, Pohunek P, Polverino E, Rademacher J, Robinson P, Snijders D, Yiallouros P, Carr SB. Lucas JS, et al. Among authors: carr sb. ERJ Open Res. 2019 Feb 1;5(1):00147-2018. doi: 10.1183/23120541.00147-2018. eCollection 2019 Feb. ERJ Open Res. 2019. PMID: 30723730 Free PMC article.
Acute bronchiolitis-Should we be doing more?
Carr SB, Main E. Carr SB, et al. Pediatr Pulmonol. 2017 Mar;52(3):279-280. doi: 10.1002/ppul.23642. Pediatr Pulmonol. 2017. PMID: 28221735 No abstract available.
Annual review or continuous assessment?
Carr SB, Dinwiddie R. Carr SB, et al. J R Soc Med. 1996;89 Suppl 27(Suppl 27):3-7. J R Soc Med. 1996. PMID: 8778447 Free PMC article. No abstract available.
Clinical utility of NGS diagnosis and disease stratification in a multiethnic primary ciliary dyskinesia cohort.
Fassad MR, Patel MP, Shoemark A, Cullup T, Hayward J, Dixon M, Rogers AV, Ollosson S, Jackson C, Goggin P, Hirst RA, Rutman A, Thompson J, Jenkins L, Aurora P, Moya E, Chetcuti P, O'Callaghan C, Morris-Rosendahl DJ, Watson CM, Wilson R, Carr S, Walker W, Pitno A, Lopes S, Morsy H, Shoman W, Pereira L, Constant C, Loebinger MR, Chung EMK, Kenia P, Rumman N, Fasseeh N, Lucas JS, Hogg C, Mitchison HM. Fassad MR, et al. J Med Genet. 2020 May;57(5):322-330. doi: 10.1136/jmedgenet-2019-106501. Epub 2019 Dec 25. J Med Genet. 2020. PMID: 31879361
Childhood bronchiectasis, so little is known.
Carr SB, Unger SA. Carr SB, et al. Arch Dis Child. 2022 Jun;107(6):523-524. doi: 10.1136/archdischild-2021-323721. Epub 2022 Mar 22. Arch Dis Child. 2022. PMID: 35318195 No abstract available.
Combined approaches, including long-read sequencing, address the diagnostic challenge of HYDIN in primary ciliary dyskinesia.
Fleming A, Galey M, Briggs L, Edwards M, Hogg C, John S, Wilkinson S, Quinn E, Rai R, Burgoyne T, Rogers A, Patel MP, Griffin P, Muller S, Carr SB, Loebinger MR, Lucas JS, Shah A, Jose R, Mitchison HM, Shoemark A, Miller DE, Morris-Rosendahl DJ. Fleming A, et al. Among authors: carr sb. Eur J Hum Genet. 2024 Apr 11. doi: 10.1038/s41431-024-01599-7. Online ahead of print. Eur J Hum Genet. 2024. PMID: 38605126
Diagnosis and management of primary ciliary dyskinesia.
Lucas JS, Burgess A, Mitchison HM, Moya E, Williamson M, Hogg C; National PCD Service, UK. Lucas JS, et al. Arch Dis Child. 2014 Sep;99(9):850-6. doi: 10.1136/archdischild-2013-304831. Epub 2014 Apr 25. Arch Dis Child. 2014. PMID: 24771309 Free PMC article. Review.
Scoliosis convexity and organ anatomy are related.
Schlösser TPC, Semple T, Carr SB, Padley S, Loebinger MR, Hogg C, Castelein RM. Schlösser TPC, et al. Among authors: carr sb. Eur Spine J. 2017 Jun;26(6):1595-1599. doi: 10.1007/s00586-017-4970-5. Epub 2017 Feb 8. Eur Spine J. 2017. PMID: 28180983
Growth and nutritional status, and their association with lung function: a study from the international Primary Ciliary Dyskinesia Cohort.
Goutaki M, Halbeisen FS, Spycher BD, Maurer E, Belle F, Amirav I, Behan L, Boon M, Carr S, Casaulta C, Clement A, Crowley S, Dell S, Ferkol T, Haarman EG, Karadag B, Knowles M, Koerner-Rettberg C, Leigh MW, Loebinger MR, Mazurek H, Morgan L, Nielsen KG, Phillipsen M, Sagel SD, Santamaria F, Schwerk N, Yiallouros P, Lucas JS, Kuehni CE; PCD Israeli Consortium; Swiss PCD Group; French Reference Centre for Rare Lung Diseases. Goutaki M, et al. Eur Respir J. 2017 Dec 21;50(6):1701659. doi: 10.1183/13993003.01659-2017. Print 2017 Dec. Eur Respir J. 2017. PMID: 29269581 Free article.
Are inhaled corticosteroids prescribed rationally in primary ciliary dyskinesia?
Dehlink E, Richardson C, Marsh G, Lee K, Jamalzadeh A, Bush A, Hogg C, Carr SB. Dehlink E, et al. Among authors: carr sb. Eur Respir J. 2018 Mar 29;51(3):1702221. doi: 10.1183/13993003.02221-2017. Print 2018 Mar. Eur Respir J. 2018. PMID: 29439021 Free article. No abstract available.
Response.
Cameron RA, Rowley M, Simmonds NJ, Whitty JA, Carr SB. Cameron RA, et al. Among authors: carr sb. Chest. 2023 Apr;163(4):e194-e195. doi: 10.1016/j.chest.2023.01.006. Chest. 2023. PMID: 37031994 No abstract available.
Time trends in diagnostic testing for primary ciliary dyskinesia in Europe.
Halbeisen FS, Shoemark A, Barbato A, Boon M, Carr S, Crowley S, Hirst R, Karadag B, Koerner-Rettberg C, Loebinger MR, Lucas JS, Maitre B, Mazurek H, Özçelik U, Martinů V, Schwerk N, Thouvenin G, Tschanz SA, Yiallouros P, Goutaki M, Kuehni CE. Halbeisen FS, et al. Eur Respir J. 2019 Oct 24;54(4):1900528. doi: 10.1183/13993003.00528-2019. Print 2019 Oct. Eur Respir J. 2019. PMID: 31273043 Free article. No abstract available.
Proceedings of the 4th BEAT-PCD Conference and 5th PCD Training School.
Gardner LE, Horton KL, Shoemark A, Lucas JS, Nielsen KG, Kobbernagel H, Rubbo B, Hirst RA, Kouis P, Ullmann N, Reula A, Rumman N, Mitchison HM, Pinto A, Richardson C, Schmidt A, Thompson J, Gaupmann R, Dabrowski M, Mill P, Carr SB, Norris DP, Kuehni CE, Goutaki M, Hogg C. Gardner LE, et al. Among authors: carr sb. BMC Proc. 2020 Jun 19;14(Suppl 8):7. doi: 10.1186/s12919-020-00191-3. eCollection 2020. BMC Proc. 2020. PMID: 32577127 Free PMC article.
The Impact on Parents of Diagnosing PCD in Young Children.
Driessens C, Carr S, Clough E, Copeland F, Dell S, Dixon L, Harris A, Knibb R, Leigh M, Narayanan M, Redfern B, Robson E, Sawras M, Schofield L, Sullivan K, Tipping M, Tran N, Walker W, Lucas JS, Behan L. Driessens C, et al. J Clin Med. 2022 Aug 16;11(16):4774. doi: 10.3390/jcm11164774. J Clin Med. 2022. PMID: 36013013 Free PMC article.
Registries and collaborative studies for primary ciliary dyskinesia in Europe.
Ardura-Garcia C, Goutaki M, Carr SB, Crowley S, Halbeisen FS, Nielsen KG, Pennekamp P, Raidt J, Thouvenin G, Yiallouros PK, Omran H, Kuehni CE. Ardura-Garcia C, et al. Among authors: carr sb. ERJ Open Res. 2020 May 26;6(2):00005-2020. doi: 10.1183/23120541.00005-2020. eCollection 2020 Apr. ERJ Open Res. 2020. PMID: 32494577 Free PMC article. Review.
De Novo Mutations in FOXJ1 Result in a Motile Ciliopathy with Hydrocephalus and Randomization of Left/Right Body Asymmetry.
Wallmeier J, Frank D, Shoemark A, Nöthe-Menchen T, Cindric S, Olbrich H, Loges NT, Aprea I, Dougherty GW, Pennekamp P, Kaiser T, Mitchison HM, Hogg C, Carr SB, Zariwala MA, Ferkol T, Leigh MW, Davis SD, Atkinson J, Dutcher SK, Knowles MR, Thiele H, Altmüller J, Krenz H, Wöste M, Brentrup A, Ahrens F, Vogelberg C, Morris-Rosendahl DJ, Omran H. Wallmeier J, et al. Among authors: carr sb. Am J Hum Genet. 2019 Nov 7;105(5):1030-1039. doi: 10.1016/j.ajhg.2019.09.022. Epub 2019 Oct 17. Am J Hum Genet. 2019. PMID: 31630787 Free PMC article.
The adaptability of the ion-binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF.
Lithgo RM, Hanževački M, Harris G, Kamps JJAG, Holden E, Gianga TM, Benesch JLP, Jäger CM, Croft AK, Hussain R, Hobman JL, Orville AM, Quigley A, Carr SB, Scott DJ. Lithgo RM, et al. Among authors: carr sb. J Biol Chem. 2023 Nov;299(11):105331. doi: 10.1016/j.jbc.2023.105331. Epub 2023 Oct 14. J Biol Chem. 2023. PMID: 37820867 Free PMC article.
Comprehensive structural, infrared spectroscopic and kinetic investigations of the roles of the active-site arginine in bidirectional hydrogen activation by the [NiFe]-hydrogenase 'Hyd-2' from Escherichia coli.
Evans RM, Beaton SE, Rodriguez Macia P, Pang Y, Wong KL, Kertess L, Myers WK, Bjornsson R, Ash PA, Vincent KA, Carr SB, Armstrong FA. Evans RM, et al. Among authors: carr sb. Chem Sci. 2023 Jul 25;14(32):8531-8551. doi: 10.1039/d2sc05641k. eCollection 2023 Aug 16. Chem Sci. 2023. PMID: 37592998 Free PMC article.
Pineal cysts: Does anyone need long-term follow up?
Tanaka T, Arnold L, Gabriela Mazuru D, Golzy M, Carr SB, Litofsky NS. Tanaka T, et al. Among authors: carr sb. J Clin Neurosci. 2021 Jan;83:146-151. doi: 10.1016/j.jocn.2020.10.051. Epub 2020 Nov 30. J Clin Neurosci. 2021. PMID: 33272885
Anaerobic fixed-target serial crystallography.
Rabe P, Beale JH, Butryn A, Aller P, Dirr A, Lang PA, Axford DN, Carr SB, Leissing TM, McDonough MA, Davy B, Ebrahim A, Orlans J, Storm SLS, Orville AM, Schofield CJ, Owen RL. Rabe P, et al. Among authors: carr sb. IUCrJ. 2020 Aug 21;7(Pt 5):901-912. doi: 10.1107/S2052252520010374. eCollection 2020 Sep 1. IUCrJ. 2020. PMID: 32939282 Free PMC article.
Successful sample preparation for serial crystallography experiments.
Beale JH, Bolton R, Marshall SA, Beale EV, Carr SB, Ebrahim A, Moreno-Chicano T, Hough MA, Worrall JAR, Tews I, Owen RL. Beale JH, et al. Among authors: carr sb. J Appl Crystallogr. 2019 Nov 14;52(Pt 6):1385-1396. doi: 10.1107/S1600576719013517. eCollection 2019 Dec 1. J Appl Crystallogr. 2019. PMID: 31798361 Free PMC article.
Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Cruz-Migoni A, Canning P, Quevedo CE, Bataille CJR, Bery N, Miller A, Russell AJ, Phillips SEV, Carr SB, Rabbitts TH. Cruz-Migoni A, et al. Among authors: carr sb. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2545-2550. doi: 10.1073/pnas.1811360116. Epub 2019 Jan 25. Proc Natl Acad Sci U S A. 2019. PMID: 30683716 Free PMC article.
Mutations in Outer Dynein Arm Heavy Chain DNAH9 Cause Motile Cilia Defects and Situs Inversus.
Fassad MR, Shoemark A, Legendre M, Hirst RA, Koll F, le Borgne P, Louis B, Daudvohra F, Patel MP, Thomas L, Dixon M, Burgoyne T, Hayes J, Nicholson AG, Cullup T, Jenkins L, Carr SB, Aurora P, Lemullois M, Aubusson-Fleury A, Papon JF, O'Callaghan C, Amselem S, Hogg C, Escudier E, Tassin AM, Mitchison HM. Fassad MR, et al. Among authors: carr sb. Am J Hum Genet. 2018 Dec 6;103(6):984-994. doi: 10.1016/j.ajhg.2018.10.016. Epub 2018 Nov 21. Am J Hum Genet. 2018. PMID: 30471717 Free PMC article.
Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment.
Quevedo CE, Cruz-Migoni A, Bery N, Miller A, Tanaka T, Petch D, Bataille CJR, Lee LYW, Fallon PS, Tulmin H, Ehebauer MT, Fernandez-Fuentes N, Russell AJ, Carr SB, Phillips SEV, Rabbitts TH. Quevedo CE, et al. Among authors: carr sb. Nat Commun. 2018 Aug 9;9(1):3169. doi: 10.1038/s41467-018-05707-2. Nat Commun. 2018. PMID: 30093669 Free PMC article.
Cloning, purification and structure determination of the HIV integrase-binding domain of lens epithelium-derived growth factor.
Hannon C, Cruz-Migoni A, Platonova O, Owen RL, Nettleship JE, Miller A, Carr SB, Harris G, Rabbitts TH, Phillips SEV. Hannon C, et al. Among authors: carr sb. Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74(Pt 3):143-149. doi: 10.1107/S2053230X18001553. Epub 2018 Feb 26. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29497017 Free PMC article.
Generating single metalloprotein crystals in well-defined redox states: electrochemical control combined with infrared imaging of a NiFe hydrogenase crystal.
Ash PA, Carr SB, Reeve HA, Skorupskaitė A, Rowbotham JS, Shutt R, Frogley MD, Evans RM, Cinque G, Armstrong FA, Vincent KA. Ash PA, et al. Among authors: carr sb. Chem Commun (Camb). 2017 May 30;53(43):5858-5861. doi: 10.1039/c7cc02591b. Chem Commun (Camb). 2017. PMID: 28504793 Free PMC article.
Reducing DNA context dependence in bacterial promoters.
Carr SB, Beal J, Densmore DM. Carr SB, et al. PLoS One. 2017 Apr 19;12(4):e0176013. doi: 10.1371/journal.pone.0176013. eCollection 2017. PLoS One. 2017. PMID: 28422998 Free PMC article.
Structural basis for DNA recognition by the transcription regulator MetR.
Punekar AS, Porter J, Carr SB, Phillips SE. Punekar AS, et al. Among authors: carr sb. Acta Crystallogr F Struct Biol Commun. 2016 Jun;72(Pt 6):417-26. doi: 10.1107/S2053230X16006828. Epub 2016 May 23. Acta Crystallogr F Struct Biol Commun. 2016. PMID: 27303893 Free PMC article.
Hydrogen activation by [NiFe]-hydrogenases.
Carr SB, Evans RM, Brooke EJ, Wehlin SA, Nomerotskaia E, Sargent F, Armstrong FA, Phillips SE. Carr SB, et al. Biochem Soc Trans. 2016 Jun 15;44(3):863-8. doi: 10.1042/BST20160031. Biochem Soc Trans. 2016. PMID: 27284053 Review.
Mechanism of hydrogen activation by [NiFe] hydrogenases.
Evans RM, Brooke EJ, Wehlin SA, Nomerotskaia E, Sargent F, Carr SB, Phillips SE, Armstrong FA. Evans RM, et al. Among authors: carr sb. Nat Chem Biol. 2016 Jan;12(1):46-50. doi: 10.1038/nchembio.1976. Epub 2015 Nov 30. Nat Chem Biol. 2016. PMID: 26619250
Intraneural Ganglions of the Hand and Wrist.
Naam NH, Carr SB, Massoud AH. Naam NH, et al. Among authors: carr sb. J Hand Surg Am. 2015 Aug;40(8):1625-30. doi: 10.1016/j.jhsa.2015.05.025. J Hand Surg Am. 2015. PMID: 26213199
Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP.
van Geersdaele LK, Stead MA, Harrison CM, Carr SB, Close HJ, Rosbrook GO, Connell SD, Wright SC. van Geersdaele LK, et al. Among authors: carr sb. Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1677-84. doi: 10.1107/S0907444913012687. Epub 2013 Aug 15. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23999291 Free article.
Structure of New Delhi metallo-β-lactamase 1 (NDM-1).
Green VL, Verma A, Owens RJ, Phillips SE, Carr SB. Green VL, et al. Among authors: carr sb. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt 10):1160-4. doi: 10.1107/S1744309111029654. Epub 2011 Sep 6. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 22102018 Free PMC article.
Structure of an Escherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 angstrom resolution.
Campeotto I, Carr SB, Trinh CH, Nelson AS, Berry A, Phillips SE, Pearson AR. Campeotto I, et al. Among authors: carr sb. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Nov 1;65(Pt 11):1088-90. doi: 10.1107/S1744309109037403. Epub 2009 Oct 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19923724 Free PMC article.
Structure of the human Nac1 POZ domain.
Stead MA, Carr SB, Wright SC. Stead MA, et al. Among authors: carr sb. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 May 1;65(Pt 5):445-9. doi: 10.1107/S1744309109012214. Epub 2009 Apr 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19407373 Free PMC article.
Structure of the wild-type human BCL6 POZ domain.
Stead MA, Rosbrook GO, Hadden JM, Trinh CH, Carr SB, Wright SC. Stead MA, et al. Among authors: carr sb. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Dec 1;64(Pt 12):1101-4. doi: 10.1107/S1744309108036063. Epub 2008 Nov 28. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 19052359 Free PMC article.
Airway function in infants newly diagnosed with cystic fibrosis.
Ranganathan SC, Dezateux C, Bush A, Carr SB, Castle RA, Madge S, Price J, Stroobant J, Wade A, Wallis C, Stocks J; London Collaborative Cystic Fibrosis Group. Ranganathan SC, et al. Among authors: carr sb. Lancet. 2001 Dec 8;358(9297):1964-5. doi: 10.1016/s0140-6736(01)06970-7. Lancet. 2001. PMID: 11747924
The role of vitamins in cystic fibrosis.
Carr SB, McBratney J. Carr SB, et al. J R Soc Med. 2000;93 Suppl 38(Suppl 38):14-9. J R Soc Med. 2000. PMID: 10911814 Free PMC article. Review. No abstract available.
Recurrent abdominal pain in childhood.
Riddell A, Carr SB. Riddell A, et al. Among authors: carr sb. Practitioner. 2000 Apr;244(1609):346-50. Practitioner. 2000. PMID: 10892055 Review. No abstract available.