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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 3
1947 4
1948 3
1949 3
1950 3
1951 11
1952 9
1953 6
1954 12
1955 7
1956 5
1957 14
1958 14
1959 17
1960 19
1961 19
1962 23
1963 46
1964 61
1965 70
1966 180
1967 215
1968 214
1969 200
1970 209
1971 186
1972 199
1973 231
1974 297
1975 369
1976 408
1977 603
1978 982
1979 1194
1980 15685
1981 33527
1982 34552
1983 35009
1984 36722
1985 37425
1986 38598
1987 39963
1988 41078
1989 42720
1990 44831
1991 46118
1992 46704
1993 47438
1994 48932
1995 49323
1996 49509
1997 49843
1998 50835
1999 52357
2000 54945
2001 56286
2002 59381
2003 63600
2004 71262
2005 77912
2006 86523
2007 93097
2008 103266
2009 110078
2010 119481
2011 128545
2012 133208
2013 138265
2014 139645
2015 140787
2016 136180
2017 131627
2018 134166
2019 136088
2020 148721
2021 156088
2022 143686
2023 144952
2024 140488
2025 134057
2026 46023
2027 2

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3,528,861 results

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Page 1
Nationwide Analysis of Sociodemographic Disparities in Health-Related Quality of Life of Colon Cancer Survivors.
Cummins KC, El Moheb M, Kim SJ, Shen C, Zaydfudim V, Ruff SM, Tsung A. Cummins KC, et al. Cancer Med. 2026 Jun;15(6):e72043. doi: 10.1002/cam4.72043. Cancer Med. 2026. PMID: 42310493
BACKGROUND: Health-related quality of life (HRQOL) measures patients' overall well-being and can help guide survivorship care. ...Advanced disease stage and baseline ADL limitations were the strongest predictors of HRQOL decline, both from pre- to post-diagnosis and from d …
BACKGROUND: Health-related quality of life (HRQOL) measures patients' overall well-being and can help guide survivorship care. ...Adv …
Aging disrupts spatiotemporal coordination in the cycling murine ovary.
Lan TCT, Kochersberger A, Raichur R, Szady S, Tran H, Simeonova R, Helmuth A, Minagar A, Orozco Fuentes MJ, Kumar V, Marrero G, Barrera I, Mangiameli S, Shalek AK, Sabeti PC, Chen F, Fischer DS, Garrison JL, Chung H. Lan TCT, et al. Nat Aging. 2026 Jun 17. doi: 10.1038/s43587-026-01140-z. Online ahead of print. Nat Aging. 2026. PMID: 42310395
Induced pluripotent stem cell-derived models of malignant nerve sheath tumor progression mimic glial to neuro-mesenchymal transition and uncover therapeutic opportunities.
Uriarte-Arrazola I, Magallón-Lorenz M, Fernández-Rodríguez J, Zhang J, Lee E, Ortega-Bertran S, Creus-Bachiller E, Farrés-Casas J, Wilson KM, McKnight C, Recabo K, Blanco I, Salvador H, Romagosa C, Lázaro C, Mazuelas H, Gel B, Ferrer M, Carrió M, Serra E. Uriarte-Arrazola I, et al. Nat Commun. 2026 Jun 17;17(1):5361. doi: 10.1038/s41467-026-73119-8. Nat Commun. 2026. PMID: 42310314
15-LOX-catalytic bias towards ether-(alkenyl)-ETE-PEs oxidation bestows selectivity of PRO-ferroptotic cell death signaling.
Tyurina YY, Mikulska-Ruminska K, Tyurin VA, Kleiboeker BA, Kapralov AA, Hashimoto A, Sparvero LJ, Dar HH, Akdogan M, Yamada K, Zhao J, Kelestemur T, Saritas E, Samovich SN, Holman TR, Bunimovich YL, Nefedova Y, Gabrilovich DI, Wenzel SE, Bahar I, Kagan VE, Bayır H. Tyurina YY, et al. Nat Commun. 2026 Jun 17;17(1):5360. doi: 10.1038/s41467-026-71869-z. Nat Commun. 2026. PMID: 42310294
Genetics of Cerebrotendinous Xanthomatosis.
Hanson J, Bonnen PE. Hanson J, et al. Mol Diagn Ther. 2026 Jun 17. doi: 10.1007/s40291-026-00855-4. Online ahead of print. Mol Diagn Ther. 2026. PMID: 42310195 Review.
BRIDGE: benchmarking large language models for understanding real-world clinical practice texts.
Wu J, Gu B, Zhou R, Xie K, Snyder D, Jiang Y, Carducci V, Wyss R, Desai RJ, Alsentzer E, Celi LA, Rodman A, Schneeweiss S, Chen JH, Romero-Brufau S, Lin KJ, Yang J. Wu J, et al. Nat Biomed Eng. 2026 Jun 17. doi: 10.1038/s41551-026-01719-2. Online ahead of print. Nat Biomed Eng. 2026. PMID: 42310130
Large language models (LLMs) are evolving rapidly and hold great promise for medical applications, yet benchmarking on real-world clinical data such as electronic health records remains limited. Most existing benchmarks rely on medical examination-style questions or PubMed …
Large language models (LLMs) are evolving rapidly and hold great promise for medical applications, yet benchmarking on real-world clinical d …
Perinatal mood and anxiety diagnoses and treatment increased among medicaid births, 2017-2021.
Zivin K, Pangori A, Tilea A, Courant A, Miller E, Hall SV, Dalton VK, Tabb KM. Zivin K, et al. Sci Rep. 2026 Jun 18. doi: 10.1038/s41598-026-57879-3. Online ahead of print. Sci Rep. 2026. PMID: 42310111
Despite funding the most births in the United States (US), we know little about basic patterns and trends of mental health conditions among Medicaid-insured women during pregnancy and after delivery. We sought to characterize the prevalence of diagnosis and treatment for p …
Despite funding the most births in the United States (US), we know little about basic patterns and trends of mental health conditions …
iSCORE-PD: an isogenic stem cell collection to research Parkinson's disease.
Busquets O, Li H, Syed KM, Jerez PA, Dunnack J, Lo Bu R, Verma Y, Pangilinan GR, Martin A, Straub J, Du Y, Simon VM, Poser S, Bush Z, Diaz J, Sahagun A, Gao J, Hong S, Hernandez DG, Levine KS, Pochet N, Booth EO, Blanchette M, Bateup HS, Rio DC, Blauwendraat C, Hockemeyer D, Soldner F. Busquets O, et al. Nat Commun. 2026 Jun 17. doi: 10.1038/s41467-026-74355-8. Online ahead of print. Nat Commun. 2026. PMID: 42310027
Contributions of the Alzheimer's Disease Neuroimaging Initiative to advancing AD research: a targeted review of recent publications.
Veitch DP, Miller MJ, Kanoria S, Aisen PS, Beckett LA, Green RC, Harvey DJ, Jack CR Jr, Jagust W, Lee EB, Nho K, Nosheny R, Okonkwo OC, Perrin RJ, Petersen RC, Mindt MR, Saykin AJ, Shaw LM, Toga AW, Tosun D, Landau SM, Weiner MW; Alzheimer's Disease Neuroimaging Initiative. Veitch DP, et al. Alzheimers Dement. 2026 Jun;22(6):e71566. doi: 10.1002/alz.71566. Alzheimers Dement. 2026. PMID: 42309987 Review.
Cognitive-behavioural therapy for insomnia in adults to decrease cannabis use: study protocol for a randomised controlled trial in a community sample of adults with frequent cannabis use.
Bolling C, Cardoni ME, Conroy DA, Price A, Goldstick JE, Bourgoise M, Bonar EE, Krystal A, Ilgen MA, Arnedt JT. Bolling C, et al. BMJ Open. 2026 Jun 17;16(6):e116524. doi: 10.1136/bmjopen-2026-116524. BMJ Open. 2026. PMID: 42309658
Primary outcomes will include the Insomnia Severity Index, 12-item Short-Form Health Survey Mental Composite Score and cannabis use frequency as assessed by the interview-administered Timeline Follow Back. ...The data from the investigation will be made available through t …
Primary outcomes will include the Insomnia Severity Index, 12-item Short-Form Health Survey Mental Composite Score and cannabis use f …
Benzylpenicillin versus flucloxacillin or cloxacillin for the treatment of penicillin-susceptible Staphylococcus aureus bacteraemia (SNAP): an international, multicentre, open-label, non-inferiority randomised controlled trial.
Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group. Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group. Lancet. 2026 Jun 17:S0140-6736(26)00761-0. doi: 10.1016/S0140-6736(26)00761-0. Online ahead of print. Lancet. 2026. PMID: 42309115
INTERPRETATION: Although the prespecified non-inferiority criterion for benzylpenicillin was not met, the probability of benzylpenicillin being non-inferior for mortality, along with a reduction in risk of AKI, indicates that benzylpenicillin should be preferred over flucloxacill …
INTERPRETATION: Although the prespecified non-inferiority criterion for benzylpenicillin was not met, the probability of benzylpenicillin be …
Caregiver COVID-19 vaccine status and its influence on pediatric vaccination decisions in a US cohort.
Ricke IJ, Ward C, Spaulding AB, Sherwood NE, Nguyen RHN. Ricke IJ, et al. Vaccine. 2026 Jun 17;88:128847. doi: 10.1016/j.vaccine.2026.128847. Online ahead of print. Vaccine. 2026. PMID: 42308977
METHODS: We analyzed data from 6395 families in the NIH ECHO Cohort with self-reported caregiver and child COVID-19 vaccination status between December 2021 and August 2023. ...
METHODS: We analyzed data from 6395 families in the NIH ECHO Cohort with self-reported caregiver and child COVID-19 vaccination statu …
A mosaic of whole-body representations on the human precentral gyrus.
Deo DR, Okorokova EV, Pritchard AL, Hahn NV, Card NS, Nason-Tomaszewski SR, Jude J, Hosman T, Choi EY, Qiu D, Meng Y, Wairagkar M, Nicolas C, Kamdar FB, Iacobacci C, Acosta A, Hochberg LR, Cash SS, Williams ZM, Rubin DB, Brandman DM, Stavisky SD, AuYong N, Pandarinath C, Downey JE, Bensmaia SJ, Henderson JM, Willett FR. Deo DR, et al. Nature. 2026 Jun 17. doi: 10.1038/s41586-026-10653-x. Online ahead of print. Nature. 2026. PMID: 42310450
The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 2026 Annual Pediatric Heart Transplantation Report, Trends and Post-transplant Outcomes by Recipient Sex.
Azeka E, Singh TP, Cherikh WS, Kim KH, Lewis A, Keller BC, Brugha R, Hsich E, Perch M, Hayes D, Dellgren G, Handarova D, Hopkinson A, Cogswell R; International Society for Heart and Lung Transplantation. Azeka E, et al. J Heart Lung Transplant. 2026 Jun 17:S1053-2498(26)01937-6. doi: 10.1016/j.healun.2026.05.029. Online ahead of print. J Heart Lung Transplant. 2026. PMID: 42309275 No abstract available.
Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia.
Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group; Lee TC, Barina LA, Walls G, Goodman AL, Yahav D, Cheng MP, Bonten M, Bowen AC, Boyles T, Daneman N, Ekkelenkamp MB, Ghanem-Zoubi N, Hensgens MPM, Jager NGL, Kaasch AJ, Kouijzer IJE, Lewis RJ, Lumley T, Lye DC, McDonald EG, McKew G, McLean ARD, McMullan BJ, McQuilten ZK, Morpeth SC, Paterson DL, Roberts JA, Robinson JO, Saito H, Scarborough M, Ten Oever J, Turner RM, Tverring J, van Hal SJ, Webb SA, Whiteway LM, Arias CA, Henderson A, Heriot GS, Snelling TL, Afra K, Ali SS, Amit S, Anagnostou NA, Archuleta S, Aston SJ, Athan E, Baharav N, Bai AD, Barber BE, Baskaran A, Berkeley MMA, Best EJ, Bhilave NR, Bloomfield MG, Bond KA, Bostock J, Botheras CL, Boyd MA, Bradshaw SME, Briggs EJ, Britton PN, Campbell AJ, Carr BZ, Chancellor JA, Chen K, Cheong EY, Chew KL, Chia PY, Chomba R, Chong BSW, Clews CJN, Cohen JM, Commons RJ, Cutfield T, Daley P, Daniel DS, Davies J, De P, Denholm JT, Di Virgilio M, Dishon-Benattar Y, Dotel R, Duan EH, Easom N, Eliakim-Raz N, England MM, Fahmy M, Findlater AR, Flanagan KL, Foo EZJ, Foo H, Forster DP, Fralick M, Frazer JL, Gador-Whyte AP, Garnham K, German GJ, Ghosh N, Gisolf EH, Giulier… See abstract for full author list ➔ Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group, et al. N Engl J Med. 2026 Jun 18;394(23):2329-2339. doi: 10.1056/NEJMoa2506905. N Engl J Med. 2026. PMID: 42308484 Clinical Trial.
CONCLUSIONS: In patients with methicillin-susceptible S. aureus bacteremia, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality and was associated with a lower incidence of acute kidney injury. (Funded by the National Health a …
CONCLUSIONS: In patients with methicillin-susceptible S. aureus bacteremia, cefazolin was noninferior to flucloxacillin or cloxacillin with …
Equity in Clinical Guidance on Application of Global Lung Function Initiative Guidelines for Pediatric Pulmonary Health Assessment.
Rastogi D, Gabbay JM, Beck AF, Ghazala ZB, Willen SM, Cohen RT, Rosas-Salazar C, Cabana MD, Teach SJ. Rastogi D, et al. Pediatrics. 2026 Jun 17. doi: 10.1542/peds.2026-076070d. Online ahead of print. Pediatrics. 2026. PMID: 42308271
Respiratory health is the result of genetics and socioenvironmental factors that influence optimal lung development and function. ...Since pulmonary symptomatology is non-specific, objective assessment of respiratory health is based on pulmonary function testing. Hi …
Respiratory health is the result of genetics and socioenvironmental factors that influence optimal lung development and function. ... …
Functional analysis of germline RUNX1 variants identified in individuals with suspected familial platelet disorder.
Menezes AC, Deuitch NT, Pintuff A, Zhen T, Wincovitch S, Ozturk K, Carter H, Ripperger T, Godley LA, Liu PP. Menezes AC, et al. Blood Adv. 2026 Jun 16:bloodadvances.2026019984. doi: 10.1182/bloodadvances.2026019984. Online ahead of print. Blood Adv. 2026. PMID: 42308221
We evaluated the functional impact of 26 RUNX1 VUSs identified in individuals referred to the NIH RUNX1 Natural History Study. Five established benign and six pathogenic variants were included as controls. ...
We evaluated the functional impact of 26 RUNX1 VUSs identified in individuals referred to the NIH RUNX1 Natural History Study. Five e …
Dynamic monitoring of antibody drug conjugates targeting TROP2 or HER2 in breast cancer using circulating tumor cells.
Mishra A, Abelman RO, Cunneely Q, Putaturo V, Deshpande AA, Bell R, Seider EM, Xu KH, Shan M, Kelly J, Huang SB, Rieur O, Knape J, Gopinathan KA, Kikkeri K, Edd JF, Walsh J, Dai CS, Ellisen LW, Ting DT, Nieman L, Toner M, Bardia A, Haber DA, Maheswaran S. Mishra A, et al. Proc Natl Acad Sci U S A. 2026 Jun 23;123(25):e2601563123. doi: 10.1073/pnas.2601563123. Epub 2026 Jun 17. Proc Natl Acad Sci U S A. 2026. PMID: 42308036
Reclassification and weighting of multiple causes of death: US death certificates 2003-2023.
Levitt M, Marten B, Oren G, Ioannidis JPA. Levitt M, et al. Proc Natl Acad Sci U S A. 2026 Jun 23;123(25):e2604493123. doi: 10.1073/pnas.2604493123. Epub 2026 Jun 17. Proc Natl Acad Sci U S A. 2026. PMID: 42308034
Systematic differences between reported and reclassified causes of death, and the choice of weighting scheme, profoundly alter disease burden estimates for several causes, with major implications for resource allocation and public health priorities....
Systematic differences between reported and reclassified causes of death, and the choice of weighting scheme, profoundly alter disease burde …
Shared spatial and temporal principles govern connectome dynamics across timescales.
Alderson TH, Jun S, Wirsich J, Egan MK, ElSayed SW, Giakas SA, Mostame P, Harper J, Giraud AL, Malone SM, Iacono WG, Koyejo S, Sadaghiani S. Alderson TH, et al. Proc Natl Acad Sci U S A. 2026 Jun 23;123(25):e2535464123. doi: 10.1073/pnas.2535464123. Epub 2026 Jun 17. Proc Natl Acad Sci U S A. 2026. PMID: 42308033
NegotiAge-An AI-Based Caregiver Negotiation Training: Results From the Multiphase Optimization Strategy (MOST) Trial.
Ramirez-Zohfeld V, Murawski A, Jobin C, Olvera C, Mell J, Brett J, Gratch J, Tschoe M, Pfammatter AF, Lindquist LA. Ramirez-Zohfeld V, et al. J Am Geriatr Soc. 2026 Jun 17. doi: 10.1111/jgs.70546. Online ahead of print. J Am Geriatr Soc. 2026. PMID: 42308028
We sought to optimize the potency and test the early effect of NegotiAge on family caregivers following the multiphase optimization strategy (MOST). PARTICIPANTS, DESIGN, SETTING: National randomized factorial trial of NegotiAge with family caregivers of PWD (> 65 years …
We sought to optimize the potency and test the early effect of NegotiAge on family caregivers following the multiphase optimization strategy …
Weight and Health Behavior Conversations in Adolescent Primary Care: A Qualitative Examination.
Darling KE, Derrick A, Smrstik E, Panza E, Goldschmidt AB, Jelalian E. Darling KE, et al. J Dev Behav Pediatr. 2026 Jun 16. doi: 10.1097/DBP.0000000000001495. Online ahead of print. J Dev Behav Pediatr. 2026. PMID: 42307973
Despite pediatricians' intentions to provide high-quality care, weight stigma and bias impede health care delivery. A shift in training is needed to optimize the experiences of adolescents with high weight status (body mass index 85th percentile) during primary care visit …
Despite pediatricians' intentions to provide high-quality care, weight stigma and bias impede health care delivery. A shift in traini …
Traumatic brain injury among hispanic children in the United States: a comprehensive systematic review of the literature.
Fouda MA, Seltzer LA, Dev A, Khan S, Hoffman C. Fouda MA, et al. Neurosurg Rev. 2026 Jun 17;49(1):450. doi: 10.1007/s10143-026-04371-1. Neurosurg Rev. 2026. PMID: 42307808 Review.
Fifteen studies met the inclusion criteria and were evaluated using the NIH Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. Hispanic children sustained TBIs at younger ages and were disproportionately affected by severe mechanisms of injury, i …
Fifteen studies met the inclusion criteria and were evaluated using the NIH Quality Assessment Tool for Observational Cohort and Cros …
Identifying caregiver-reported modifiable barriers to pediatric oncology clinical trial enrollment and participation.
Whitmire R, Wikstrom D, Lockridge R, Holland E, Van Sprang A, Toledo-Tamula MA, Akshintala S, Kaplan RN, Wolters PL, Martin S. Whitmire R, et al. Support Care Cancer. 2026 Jun 17;34(7):666. doi: 10.1007/s00520-026-10843-3. Support Care Cancer. 2026. PMID: 42307694
METHODS: English- and/or Spanish-speaking caregivers of children diagnosed with cancer in the last 5 years completed the Research Participation Survey - Caregiver (RPS-C) assessing caregiver-reported barriers to ClTr participation, the validated Health Literacy Survey-12 ( …
METHODS: English- and/or Spanish-speaking caregivers of children diagnosed with cancer in the last 5 years completed the Research Participat …
Bintrafusp alfa for patients with recurrent or metastatic olfactory neuroblastoma.
London NR Jr, Bracken-Clarke D, Xue E, Brownell I, Mydlarz WK, Turkbey EB, Cordes LM, Marté JL, Rooper LM, Shah SB, Manu M, Sargi ZB, Gulley JL, Floudas CS. London NR Jr, et al. Cancer Immunol Immunother. 2026 Jun 17. doi: 10.1007/s00262-026-04462-4. Online ahead of print. Cancer Immunol Immunother. 2026. PMID: 42307670
Treatment of Cardiometabolic Risk Factors Among U.S. Adults With Cardiovascular-Kidney-Metabolic Syndrome.
Gong J, Chiu N, Clinch KA, Qian Y, Ho JE, Wadhera RK. Gong J, et al. J Am Coll Cardiol. 2026 Jun 17:S0735-1097(26)06350-3. doi: 10.1016/j.jacc.2026.04.031. Online ahead of print. J Am Coll Cardiol. 2026. PMID: 42307495
OBJECTIVES: The purpose of this study was to characterize national treatment rates of hypertension, diabetes, and hyperlipidemia among U.S. adults with CKM syndrome and to assess risk factor control among treated individuals from 2015 through 2023. ...Among r …
OBJECTIVES: The purpose of this study was to characterize national treatment rates of hypertension, diabetes, and hyperlipidemia amon …
Resistance Training, Aerobic Activity, Television Viewing, and Risk of Major Cardiovascular Events in U.S. Women.
Zhang T, Zhang Y, Lee DH, Rezende LFM, Wang X, Zheng C, Giovannucci E. Zhang T, et al. J Am Coll Cardiol. 2026 May 25:S0735-1097(26)06355-2. doi: 10.1016/j.jacc.2026.04.036. Online ahead of print. J Am Coll Cardiol. 2026. PMID: 42307492
METHODS: We conducted a prospective cohort study among 117,025 women from the Nurses' Health Study (N = 45,669; 2002-2020) and Nurses' Health Study II (N = 71,356; 2003-2017), with up to 5 repeated assessments of physical activity. ...CONCLUSIONS: In this large pros …
METHODS: We conducted a prospective cohort study among 117,025 women from the Nurses' Health Study (N = 45,669; 2002-2020) and Nurses …
Magnetic Resonance Markers of Supraspinatus Muscle Microvascular Function and Energetics Following a Rotator Cuff Tear.
Cooper KJ, Walter GA, Farmer KW, Hotchkiss ZA, Forbes SC, Pozzi F. Cooper KJ, et al. J Appl Physiol (1985). 2026 Jun 17. doi: 10.1152/japplphysiol.01210.2025. Online ahead of print. J Appl Physiol (1985). 2026. PMID: 42307471
Overall, these findings support that the post-contractile BOLD response and 31P-MRS may be valuable markers to assess shoulder muscle health status and evaluate therapeutic interventions aimed at improving clinical outcomes following a rotator cuff tear....
Overall, these findings support that the post-contractile BOLD response and 31P-MRS may be valuable markers to assess shoulder muscle hea
Child Opportunity Index and 30-Day Readmission Among Children Discharged With New Long-Term Mechanical Ventilation via Tracheostomy: A Pediatric Health Information System Database Study, 2014-2023.
Scheller LL, Alkon A, Hoffmann TJ, Staveski S, Foster CC, Russell CJ. Scheller LL, et al. Pediatr Crit Care Med. 2026 Jun 18. doi: 10.1097/PCC.0000000000003989. Online ahead of print. Pediatr Crit Care Med. 2026. PMID: 42307269
OBJECTIVES: To examine the association between neighborhood-level social determinants of health (SDOH), as measured by the Child Opportunity Index (COI), and 30-day all-cause same-hospital readmission among children newly discharged on long-term mechanical ventilation via …
OBJECTIVES: To examine the association between neighborhood-level social determinants of health (SDOH), as measured by the Child Oppo …
Is 5.5 cm Still the Optimal Size Threshold to Treat AAA in Men? A Contemporary Cost-Utility Analysis.
Columbo JA, Scali ST, Wanhainen A, Neal D, Ponukumati AS, Huber TS, Debus S, Scully RE, Cooper M, Goodney PP, Upchurch G, Stone DH. Columbo JA, et al. Ann Surg. 2026 Jun 18. doi: 10.1097/SLA.0000000000007134. Online ahead of print. Ann Surg. 2026. PMID: 42307253
Two willingness-to-pay(WTP) thresholds were evaluated:$100,000/QALY(U.S.) and $40,000/QALY(UK-NICE equivalent). Given uncertainty in size-specific rupture risk, a range of annual rupture probabilities was modeled. ...Given that contemporary data suggest lower ruptur …
Two willingness-to-pay(WTP) thresholds were evaluated:$100,000/QALY(U.S.) and $40,000/QALY(UK-NICE equivalent). Given uncertai …
Photo-Crosslinking Aided Hierarchical Assembly of Recombinant Collagen Hydrogels for 3D Bio-Printing.
Wang C, Zhang M, Xu F. Wang C, et al. Biotechnol J. 2026 Jun;21(6):e70259. doi: 10.1002/biot.70259. Biotechnol J. 2026. PMID: 42307070
Further, the RCMA hydrogel demonstrated robust printability in 3D bio-printing, showing potential for constructing intricate biological architectures. Moreover, NIH-3T3 cell culture demonstrated excellent biocompatibility and negligible cytotoxicity of the RCMA hydrogel, w …
Further, the RCMA hydrogel demonstrated robust printability in 3D bio-printing, showing potential for constructing intricate biological arch …
A high-throughput fluorescent DNA cleavage assay for discovering bacterial DNA gyrase poisons.
Dias M, Annamalai T, Otsuka Y, Leng S, Chapagain T, Ferdous S, Shumate J, Scampavia L, Spicer TP, Leng F. Dias M, et al. Nucleic Acids Res. 2026 Jun 8;54(11):gkag610. doi: 10.1093/nar/gkag610. Nucleic Acids Res. 2026. PMID: 42306948
Antimicrobial resistance is a major global public health threat, yet no new antibiotic class has been introduced in over 30 years. Fluoroquinolones (FQs), a type of bacterial DNA gyrase poison, are potent antibiotics which stabilizes gyrase-DNA cleavage complexes and there …
Antimicrobial resistance is a major global public health threat, yet no new antibiotic class has been introduced in over 30 years. Fl …
Rigor and Transparency in Two Neurotrauma-Publishing Journals: Editorial Policies Improve Transparent Reporting.
Bandrowski A, Namburi A, Ferguson A, Floyd CL, Martone ME; PRECISE-TBI Investigators. Bandrowski A, et al. J Neurotrauma. 2026 Jun 17:8977151261450399. doi: 10.1177/08977151261450399. Online ahead of print. J Neurotrauma. 2026. PMID: 42306830
This shows that the Journal of Neurotrauma's required rigor section is effective in improving reporting, but it would be far better if sex as a biological variable and transparent reporting of reagents (items present on major checklists, including NIH rigor criteria) would …
This shows that the Journal of Neurotrauma's required rigor section is effective in improving reporting, but it would be far better if sex a …
INTACT: a method for integration of longitudinal physical activity data from multiple sources.
Zhang J, Cui E, Li H, Shou H. Zhang J, et al. Biometrics. 2026 Jun 17:ujag112. doi: 10.1093/biomtc/ujag112. Online ahead of print. Biometrics. 2026. PMID: 42306821
We apply the proposed method to two real-world applications: (1) integration of accelerometer data from two waves of the National Health and Nutrition Examination Survey (NHANES), measured using different devices and reported in different units; and (2) integration …
We apply the proposed method to two real-world applications: (1) integration of accelerometer data from two waves of the National
Safety and efficacy of AST-001 in children with autism spectrum disorder: a 52-week multicenter long-term follow-up study.
Kim JI, Kim HW, Kim JH, Lee M, Hwang SK, Joung YS. Kim JI, et al. Front Psychiatry. 2026 Jun 1;17:1783915. doi: 10.3389/fpsyt.2026.1783915. eCollection 2026. Front Psychiatry. 2026. PMID: 42305848 Free PMC article. Clinical Trial.
CLINICAL TRIAL REGISTRATION: https://cris.nih.go.kr/cris/search/detailSearch.do?seq=26492&search_page=L&search_lang=&class_yn=, identifier KCT0007519....
CLINICAL TRIAL REGISTRATION: https://cris.nih.go.kr/cris/search/detailSearch.do?seq=26492&search_page=L&search_lang=&clas …
Public attitudes toward cascade genetic screening in the United States.
Smith HS, Zoltick ES, Hickingbotham MR, Bonkowski ES, Pereira S, Lavelle TA, Veenstra DL, McGuire AL, Bonini KE, Jamal L. Smith HS, et al. Health Aff Sch. 2026 Jun 4;4(6):qxag138. doi: 10.1093/haschl/qxag138. eCollection 2026 Jun. Health Aff Sch. 2026. PMID: 42305713 Free PMC article.
INTRODUCTION: After a patient receives genetic test results that indicate an actionable health condition, cascade genetic screening (CGS) is the process of evaluating the patient's relatives for a potentially elevated genetic risk of disease. ...
INTRODUCTION: After a patient receives genetic test results that indicate an actionable health condition, cascade genetic screening ( …
Cumulative genetic risk for asthma contributes to disease severity in children with asthma.
Dapas M, Wentworth-Sheilds W, Thompson EE, Kumar R, Lippner E, Wood RA, O'Connor GT, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Bacharier LB, Lovinsky-Desir S, Gill MA, Sheehan WJ, Patel SJ, Altman MC, Gern JE, Visness CM, Gergen PJ, Becker PM, Jackson DJ, Ober C. Dapas M, et al. J Allergy Clin Immunol Glob. 2026 May 14;5(4):100733. doi: 10.1016/j.jacig.2026.100733. eCollection 2026 Jul. J Allergy Clin Immunol Glob. 2026. PMID: 42305392 Free PMC article.
Investigation on the Cytotoxicity of Hydroxycinnamic and Hydroxybenzoic Acid-Based Natural Antioxidant Conjugated Terpyridine Analogues toward Triple-Negative Breast Cancer.
Roy A, Beniwal N, Shome A, Rengan AK, Chinta JP. Roy A, et al. ACS Med Chem Lett. 2026 May 19;17(6):1316-1325. doi: 10.1021/acsmedchemlett.6c00124. eCollection 2026 Jun 11. ACS Med Chem Lett. 2026. PMID: 42305218 Free PMC article.
Due to the presence of natural antioxidant residues, all these derivatives were found to be biocompatible, as studied over NIH/3T3 cell lines. These results illustrate the involvement of ROS-generated cytotoxic intermediates, responsible for the therapeutic applicability o …
Due to the presence of natural antioxidant residues, all these derivatives were found to be biocompatible, as studied over NIH/3T3 ce …
NIH Funding for Artificial Intelligence in Surgical Specialties: Allocation and Alignment with US Disease Burden.
Gorijavolu R, Cho A, Boparai S, Johal AS, Mathur V, Ciftci Y, Shoyombo I, King EA, Celi LA, Stey AM. Gorijavolu R, et al. J Am Coll Surg. 2026 Jun 17. doi: 10.1097/XCS.0000000000002065. Online ahead of print. J Am Coll Surg. 2026. PMID: 42305075
BACKGROUND: National Institutes of Health (NIH) investment in artificial intelligence (AI) within surgical specialties is rapidly expanding, yet whether funding aligns with disease burden or reflects structural disparities remains unclear. STUDY DESIGN …
BACKGROUND: National Institutes of Health (NIH) investment in artificial intelligence (AI) within surgical speci …
A randomized controlled trial on the impact of bovhyaluronidase azoximer on ejaculate biofilms in patients with chronic prostatitis.
Andrey M, Stanislav V, Elizaveta B, Margarita B, Ofelia M, Dmitry Z, Sergey A, Dmitry K, Mikhail E, Leonid R, Magomed G, Leonid S. Andrey M, et al. Urologia. 2026 Jun 16:3915603261453123. doi: 10.1177/03915603261453123. Online ahead of print. Urologia. 2026. PMID: 42304882
METHODS: Patients with chronic bacterial prostatitis and infertility completed the NIH-CPSI, IPSS, and QoL questionnaires, underwent microbiological culture of prostatic secretion, ejaculate, or the third portion of urine, light and electron microscopy of ejaculate before …
METHODS: Patients with chronic bacterial prostatitis and infertility completed the NIH-CPSI, IPSS, and QoL questionnaires, underwent …
Partial body mass regain attenuates lipid utilization and alters the hepatic lipidome linked to HDL dysfunction during metabolic syndrome in male rats.
Jardines EE, Cornejo MA, Newman JW, Fiehn O, Nishiyama A, Ortiz RM. Jardines EE, et al. Physiol Rep. 2026 Jun;14(12):e70865. doi: 10.14814/phy2.70865. Physiol Rep. 2026. PMID: 42304822
This study highlights the detriments of PR during MetS, suggesting that careful health monitoring is necessary for individuals with compromised metabolism when using dietary interventions to ameliorate MASLD....
This study highlights the detriments of PR during MetS, suggesting that careful health monitoring is necessary for individuals with c …
Simulating physiological blood maintenance: A dialysis-integrated in vitro flow loop for realistic hemocompatibility evaluation of devices.
Gölcez T, Kul D, Uğurel E, Günaydın İ, Yalçın Ö, Pekkan K, Yıldız Y. Gölcez T, et al. Int J Artif Organs. 2026 Jun 16:3913988261445012. doi: 10.1177/03913988261445012. Online ahead of print. Int J Artif Organs. 2026. PMID: 42304801
Blood was circulated for 12 and 48 h, and hemolysis (NIH, pfHb, bilirubin, haptoglobin), blood gases (pH, glucose, lactate), inflammation (IL-8, TNF-alpha, C3a), coagulation (fibrinogen, TAT), platelet/endothelial activation (beta-TG, vWF), and ferritin levels were measure …
Blood was circulated for 12 and 48 h, and hemolysis (NIH, pfHb, bilirubin, haptoglobin), blood gases (pH, glucose, lactate), inflamma …
The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics.
Cree IA, Arends MJ, Khoury JD, Denton ERE, Gill AJ, Lazar AJ, Frayling IM, Pfister SM, Rubin MA, Leite KRM, Dalgleish R, Bruford EA, Plon SE, Hamosh A, Walsh MF, Goldman-Lévy G, Wijesinghe H, Foulkes WD, Lokuhetty D. Cree IA, et al. Clin Genet. 2026 Jun 16. doi: 10.1111/cge.70195. Online ahead of print. Clin Genet. 2026. PMID: 42304730
MelOD: The Melanoma Omics Dashboard for Multimodal Data Exploration.
Sastourne-Haletou P, Walker A, Annuar D, Subudhi I, Karz A, Berico P, Salgado PA, Ibrahim M, Osman I, Schober M, Hernando E, Ruggles KV. Sastourne-Haletou P, et al. Pigment Cell Melanoma Res. 2026 Jul;39(4):e70101. doi: 10.1111/pcmr.70101. Pigment Cell Melanoma Res. 2026. PMID: 42304720
Analysis of in vitro profiling data of cosmetic ingredients within the Tox21 10K compound library for bioactivity and potential toxicity.
Kruger L, Ngan DK, Xu T, Xia M, Ferguson SS, Reif DM, Simeonov A, Huang R. Kruger L, et al. BMC Pharmacol Toxicol. 2026 Jun 16. doi: 10.1186/s40360-026-01165-5. Online ahead of print. BMC Pharmacol Toxicol. 2026. PMID: 42304516
BACKGROUND: Cosmetics are defined by the U.S. Food and Drug Administration (FDA) as "articles intended to be rubbed, poured, sprinkled, or sprayed on, introduced into, or otherwise applied to the human body for cleansing, beautifying, promoting attractiveness, or al …
BACKGROUND: Cosmetics are defined by the U.S. Food and Drug Administration (FDA) as "articles intended to be rubbed, poured, s …
Factors Associated With Alcohol Intake in Patients With Newly Diagnosed Breast Cancer.
Rajput S, Vierkant RA, Larson NL, Stan DL, Mussallem DM, D'Andre SD, Couch FJ, Olson JE, O'Sullivan CC, Ruddy KJ. Rajput S, et al. Cancer Med. 2026 Jun;15(6):e72031. doi: 10.1002/cam4.72031. Cancer Med. 2026. PMID: 42304465
Tumor stage, tumor receptors, and BRCA mutation status were not associated with alcohol intake. PROMIS-10 physical health scores correlated with alcohol intake in univariate but not multivariate models. ...
Tumor stage, tumor receptors, and BRCA mutation status were not associated with alcohol intake. PROMIS-10 physical health scores corr …
Final analysis of phase 2 clinical trial of ruxolitinib and azacitidine combination therapy in patients with myelodysplastic syndrome/myeloproliferative neoplasms.
Arora S, Senapati J, Deshmukh I, Bose P, Masarova L, Loghavi S, Wang X, Nogueras-Gonzalez G, Montalban-Bravo G, Borthakur G, DiNardo CD, Kadia T, Zhou L, Saenz D, Halim H, Alvarado Y, Ohanian M, Takahashi K, Short NJ, Jabbour E, Ravandi F, Garcia-Manero G, Pemmaraju N, Daver NG. Arora S, et al. J Hematol Oncol. 2026 Jun 16. doi: 10.1186/s13045-026-01813-7. Online ahead of print. J Hematol Oncol. 2026. PMID: 42304430
Entrepreneurship beyond the lab: commercializing your creative outputs.
Martínez-Montemayor MM, Raghu S, Torres-Reverón A. Martínez-Montemayor MM, et al. BMC Proc. 2026 Jun 16;18(Suppl 1):33. doi: 10.1186/s12919-026-00383-3. BMC Proc. 2026. PMID: 42304421
However, many of these researchers may not be familiar with determining whether their ideas can be turned into a viable product and made sellable. Educational programs such as the National Science Foundation I-Corps Program and I-RED from the National Institute of G …
However, many of these researchers may not be familiar with determining whether their ideas can be turned into a viable product and made sel …
The hidden hand in retail: a qualitative analysis of how ultra-processed food companies shape consumer purchasing.
Winkler MR, Sundermeir SM, Antonacci CC, Laska MN. Winkler MR, et al. BMC Med. 2026 Jun 16. doi: 10.1186/s12916-026-04968-9. Online ahead of print. BMC Med. 2026. PMID: 42304361
BACKGROUND: Ultra-processed foods (UPFs) are increasingly recognized for their health harms, yet consumer selection of UPFs is strongly shaped by retail marketing strategies. ...Enhanced regulation of the 4Ps and counter-marketing campaigns that reveal overlooked marketing …
BACKGROUND: Ultra-processed foods (UPFs) are increasingly recognized for their health harms, yet consumer selection of UPFs is strong …
Trajectory and predictors of cancer- and treatment-related fatigue (CRF) in adolescent and young adult cancer patients: a prospective, longitudinal study.
Chan A, Chan D, Agrawal P, Beppu LL, Kober K, Ng DQ, Sayer M, Trudeau J. Chan A, et al. BMC Cancer. 2026 Jun 16. doi: 10.1186/s12885-026-16324-4. Online ahead of print. BMC Cancer. 2026. PMID: 42304319
METHODS: Newly diagnosed AYAC (15-39 years old) and non-cancer controls (NC) recruited from National Cancer Centre Singapore completed clinical assessments and provided blood draws for inflammatory cytokine measurements every 3 months up to 12 months. ...
METHODS: Newly diagnosed AYAC (15-39 years old) and non-cancer controls (NC) recruited from National Cancer Centre Singapore complete …
Layer-by-Layer Surface-Modified Supramolecular Fullerene Microrods for Cell Feeding.
Yang PS, Hsu SH, Uto K, Ma R, Ariga K, Shrestha LK. Yang PS, et al. ACS Appl Mater Interfaces. 2026 Jun 16. doi: 10.1021/acsami.6c10978. Online ahead of print. ACS Appl Mater Interfaces. 2026. PMID: 42304186
The impact of the surface-modified FMR-P/G_12 h sample on the biological behavior of NIH/3T3 fibroblasts was explored to assess its potential for biomedical applications. When FMR-P/G_12 h was used to treat NIH/3T3 fibroblasts, the cells exhibited markedly enhanced …
The impact of the surface-modified FMR-P/G_12 h sample on the biological behavior of NIH/3T3 fibroblasts was explored to assess its p …
Beyond Water, Rest, and Shade: Advancing Farmworker Heat Protection Through Partnership.
Elliott A, Anand S, Craig Heller H, Orellana E, Nieves MC, Ley C, Rath MM, Yu X, Bevill D, Flores L, Casa D, Chicas R, Hertzberg VS, Riden H, Fathallah FA, Glaser J, Morrissey-Basler MC, Parsonnet J. Elliott A, et al. Am J Ind Med. 2026 Jun 16. doi: 10.1002/ajim.70105. Online ahead of print. Am J Ind Med. 2026. PMID: 42304140
Heat affects farmworker health and productivity. As occupational heat exposure intensifies, cooling devices that extract body heat could protect farmworkers. ...In this commentary, we first describe how heat affects farmworker health and review current heat illness …
Heat affects farmworker health and productivity. As occupational heat exposure intensifies, cooling devices that extract body heat co …
Brain regional susceptibility to tauopathy in individuals at risk for chronic traumatic encephalopathy.
Wiegand TLT, Rubinski A, Jung LB, Franzmeier N, Arciniega H, Ravanfar P, Dewenter A, Alosco ML, Tripodis Y, Su Y, Protas H, Lin AP, Pasternak O, Chen K, Coleman MJ, Bouix S, Adler CH, Balcer LJ, Bernick C, Cummings JL, Stern RA, Reiman EM, Shenton ME, Ewers M, Koerte IK; DIAGNOSE CTE Research Project. Wiegand TLT, et al. Alzheimers Dement. 2026 Jun;22(6):e71503. doi: 10.1002/alz.71503. Alzheimers Dement. 2026. PMID: 42304137 Free PMC article.
Author Correction: Ontogeny and transcriptional regulation of Thetis cells.
Paucar Iza YA, Park T, Baker E, Shibu G, Hoelting T, Feather G, Yadav A, Parisotto YF, Zhao Z, Akagbosu B, Bayes ME, Fisher L, James LM, Ma J, Philpot BD, Afzali B, Leslie C, Brown CC. Paucar Iza YA, et al. Nature. 2026 Jun 16. doi: 10.1038/s41586-026-10770-7. Online ahead of print. Nature. 2026. PMID: 42304116 No abstract available.
Enteropathy produced in mice by intergenerational transmission of small intestinal microbiota from undernourished children.
Pruss KM, Kao C, Byrne AE, Chen RY, Di Luccia B, Karvelyte L, Coskun R, Lemieux M, Nepal K, Webber DM, Hibberd MC, Wang Y, Liu H, Rodionov DA, Osterman AL, Colonna M, Maueroder C, Ravichandran K, Barratt MJ, Ahmed T, Gordon JI. Pruss KM, et al. Nat Microbiol. 2026 Jun 16. doi: 10.1038/s41564-026-02394-4. Online ahead of print. Nat Microbiol. 2026. PMID: 42304079
Circulating lipids are related to longitudinal changes of ATN biomarkers for Alzheimer's disease.
Kim JP, Nho K, Wang T, Huynh K, Arnold M, Risacher SL, Bice PJ, Han X, Kristal BS, Blach C, Baillie R, Kastenmüller G, Meikle PJ, Saykin AJ, Kaddurah-Daouk R; Alzheimer’s Disease Neuroimaging Initiative; Alzheimer’s Disease Metabolomics Consortium (ADMC). Kim JP, et al. Mol Psychiatry. 2026 Jun 16. doi: 10.1038/s41380-026-03626-z. Online ahead of print. Mol Psychiatry. 2026. PMID: 42304066
Detection of MEN1 resistance mutations in cell-free DNA from acute leukemia patients treated with menin inhibitors.
Shukla N, Charalambous K, Li S, Ko KH, Casanova H, Buehler E, Cobbs C, Patel R, Brannon AR, Ewalt MD, Sulis ML, Carroll WL, Arcila ME, Mohibullah N, Berger M, Levine RL, Stein EM, Shah R, Cai SF. Shukla N, et al. Blood Cancer J. 2026 Jun 16;16(1):94. doi: 10.1038/s41408-026-01545-4. Blood Cancer J. 2026. PMID: 42303978 Free PMC article. No abstract available.
Intrinsic capacity and mortality in community-dwelling octogenarians: a network analysis from the ilSIRENTE study.
Cacciatore S, Bravo B, Zeidan RS, Calvani R, Yoon HA, Tosato M, Russo A, Leeuwenburgh C, Anton SD, Marzetti E, Landi F. Cacciatore S, et al. Geroscience. 2026 Jun 16. doi: 10.1007/s11357-026-02370-0. Online ahead of print. Geroscience. 2026. PMID: 42303956
However, the correlations among IC domains and their association with health outcomes in very old adults remain unclear. This study aimed to characterise the relationships among IC domains using network analysis and to examine their association with mortality in community- …
However, the correlations among IC domains and their association with health outcomes in very old adults remain unclear. This study a …
Intergenerational Associations of Childhood War Exposure, Adverse Childhood Experiences, and Mental Health in Offspring of Lebanese Immigrants.
A Ali D, Mikulich-Gilbertson S, Epperson CN. A Ali D, et al. J Immigr Minor Health. 2026 Jun 16. doi: 10.1007/s10903-026-01942-8. Online ahead of print. J Immigr Minor Health. 2026. PMID: 42303938
Lebanese Americans, the largest Arab ethnic group in the United States, remain underrepresented in mental health research despite collective exposure to conflict, displacement, and immigration. This study examined intergenerational associations of parental childhood war ex …
Lebanese Americans, the largest Arab ethnic group in the United States, remain underrepresented in mental health research despite col …
Sociodemographic disparities and reasons for delayed healthcare among U.S. cancer survivors: an All of Us study.
Ng DQ, Zheng Z, Jemal A, Chan A, Islami F. Ng DQ, et al. Support Care Cancer. 2026 Jun 16;34(7):663. doi: 10.1007/s00520-026-10880-y. Support Care Cancer. 2026. PMID: 42303910 Free PMC article.
OBJECTIVE: To examine how sociodemographic factors influence healthcare access among cancer survivors. METHODS: From the National Institutes of Health's All of Us dataset (2018-2022, n = 27,589), we analyzed the relationship between characteristics like age, …
OBJECTIVE: To examine how sociodemographic factors influence healthcare access among cancer survivors. METHODS: From the National
Relationships between Toenail, Urinary, and Drinking-water Fluoride Concentrations in a Pregnancy Cohort using Private Water Systems in the United States.
Tamayo-Cabeza G, Martínez-Mier EA, Castiblanco-Rubio GA, Lippert F, Peacock JL, Till C, Goodman CV, Flora DB, Lanphear BP, Korrick SA, Karagas MR. Tamayo-Cabeza G, et al. Biol Trace Elem Res. 2026 Jun 17. doi: 10.1007/s12011-026-05182-7. Online ahead of print. Biol Trace Elem Res. 2026. PMID: 42303861
To assess the strength of the relationships between fluoride concentrations in tap water, toenails, and urine in a U.S. cohort of pregnant participants using private, unregulated water systems. We analyzed fluoride concentrations in residential tap water directly wi …
To assess the strength of the relationships between fluoride concentrations in tap water, toenails, and urine in a U.S. cohort …
Long-term exposure to outdoor air pollutants and risk of pancreatic cancer in a large prospective U.S.-based cohort.
Chtourou A, Marcus Post L, Fisher JA, Stolzenberg-Solomon R, Kaufman JD, Silverman DT, Jones RR. Chtourou A, et al. J Expo Sci Environ Epidemiol. 2026 Jun 16. doi: 10.1038/s41370-026-00929-9. Online ahead of print. J Expo Sci Environ Epidemiol. 2026. PMID: 42303835
METHODS: We estimated historical pollutant concentrations at enrollment (1995-1996) residences in the NIH-AARP Diet and Health Study (N = 486,431). We estimated hazard ratios and 95% confidence intervals (HR [CI]) for associations (continuous and categorical) with i …
METHODS: We estimated historical pollutant concentrations at enrollment (1995-1996) residences in the NIH-AARP Diet and Health
The association between slow wave activity and memory improvement following cognitive-behavioral therapy for insomnia in older adults: A secondary analysis of a randomized clinical trial​.
Ahmadi M, Krause AJ, O'Hora KP, Blozyte-Sakenis E, Hernandez B, Lazzeroni LC, Zeitzer JM, Friedman L, Posner D, Kushida C, Manber R, Yesavage J, Saletin JM, Goldstein-Piekarski AN. Ahmadi M, et al. J Clin Sleep Med. 2026 Jun 16;22(1):93. doi: 10.1007/s44470-026-00087-7. J Clin Sleep Med. 2026. PMID: 42303834 Clinical Trial.
GWAS meta-analysis provides new insights into uveal melanoma risk.
D'Mellow M, Wang H, Palmer JM, Hemminki K, Cebulla CM, Beasley AB, Bechrakis NE, Pritchard AL, Wadt KW, Johansson PA, Mobuchon L, Barlow S, Brooks K, Beckman T, Olsen CM, Warrier SK, Byrne L, Kalirai H, Mustard C, Ingold N, Försti A, Isaacs T, Jayasinghe GJMSR, Glasson WJ, Williamson G, McGrath LA, Le NQ, Chadha V, Gray ES, Brown KM, Cauchi P, Thomsen H, Connolly J, MacGregor S, Whiteman DC, Kiilgaard JF, Stern MH, Coupland SE, Abdel-Rahman MH, Zeschnigk M, Hayward N, Law MH. D'Mellow M, et al. Br J Cancer. 2026 Jun 16. doi: 10.1038/s41416-026-03499-7. Online ahead of print. Br J Cancer. 2026. PMID: 42303830
Mind Melodies: An NLP platform to examine music cognition.
García AM, Welford AS, Ponferrada J, Ferrante FJ, Avendaño C, Pérez G, Birba A, Caro I, Saavedra JF, Grisales DE, Mesz B. García AM, et al. Behav Res Methods. 2026 Jun 16;58(7):198. doi: 10.3758/s13428-026-03059-0. Behav Res Methods. 2026. PMID: 42303808
Whole blood epigenomic and transcriptomic characterization identifies vulnerable molecular subtypes of chronic coronary disease.
Muller M, Cornwell MG, Rajkumar S, Chen Z, Coit D, Drouard G, Sastourne-Haletou P, Yang H, Raitakari O, Lehtimäki T, Hochman J, Maron DJ, Berger JS, Newman JD, Ruggles KV; ISCHEMIA Biorepository Research Group. Muller M, et al. Nat Commun. 2026 Jun 16. doi: 10.1038/s41467-026-73815-5. Online ahead of print. Nat Commun. 2026. PMID: 42303606 Free article.
To address this gap, our study leverages high-dimensional molecular data from the ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) Trials biorepository to molecularly characterize patients with CCD. ...
To address this gap, our study leverages high-dimensional molecular data from the ISCHEMIA (International Study of Comparative Health
Patterns of Chronic Stress in Diurnal Salivary Cortisol Already Predict Epigenetic Age Acceleration in Young Adults in the Cebu Longitudinal Health and Nutrition Survey.
Post SR, Ryan CP, Lee NR, Carba DB, Bechayda SA, MacIsaac JL, Dever K, Lin DTS, Atashzay P, Kobor MS, Kuzawa CW. Post SR, et al. Am J Hum Biol. 2026 Jun;38(6):e70290. doi: 10.1002/ajhb.70290. Am J Hum Biol. 2026. PMID: 42303423
To address this gap, we use data from the Cebu Longitudinal Health and Nutrition Survey (CLHNS) to explore linear relationships between diurnal salivary cortisol and a suite of epigenetic clocks. ...Additionally, DNA methylation was measured in whole blood to calculate EAA …
To address this gap, we use data from the Cebu Longitudinal Health and Nutrition Survey (CLHNS) to explore linear relationships betwe …
Early outpatient follow-up, hospital-free survival, and health-related quality of life in older adults after hospitalization for acute myocardial infarction.
Hajduk A, Kern LM, Falvey JR, Shang J, Herrin J, Tsang S, Aviles A, Chaudhry SI. Hajduk A, et al. J Hosp Med. 2026 Jun 16. doi: 10.1002/jhm.70361. Online ahead of print. J Hosp Med. 2026. PMID: 42303270
We used inverse-probability of treatment-weighted analyses to evaluate associations of early outpatient follow-up with hospital-free survival and physical and health-related quality of life 180 days post-discharge. More than two-fifths of the 1539 participants had a follow …
We used inverse-probability of treatment-weighted analyses to evaluate associations of early outpatient follow-up with hospital-free surviva …
Mechanistic insights into Bluetongue virus immunodynamics: a Bayesian within-host modelling approach.
Majumder A, Westrich JA, McNulty E, Sherman T, Carpenter M, Mayo C, Mathiason C, Perkins A. Majumder A, et al. J R Soc Interface. 2026 Jun 17;23(239):20251309. doi: 10.1098/rsif.2025.1309. J R Soc Interface. 2026. PMID: 42303268
Bluetongue virus (BTV) is a vector-transmitted orbivirus that infects ruminant livestock and wildlife, causing substantial economic losses owing to its impact on animal health and trade. Despite extensive study, the mechanisms underlying infection and immune dynamics remai …
Bluetongue virus (BTV) is a vector-transmitted orbivirus that infects ruminant livestock and wildlife, causing substantial economic losses o …
Immune System Evaluation of Echinacea Purpurea Root Extract in Female Harlan Sprague Dawley (Hsd:Sprague Dawley SD) Rats.
Johnson VJ, Waidyanatha S, Germolec DR, Cora MC, Cesta MF, Shockley KR, Jeffers A, Cimon K, Mutlu E, Cristy T, Pierfellice J, Luster MI, Burleson GR, Ryan K. Johnson VJ, et al. Food Chem Toxicol. 2026 Jun 16:116226. doi: 10.1016/j.fct.2026.116226. Online ahead of print. Food Chem Toxicol. 2026. PMID: 42303080
Unfortunately, determining risk posed to human health is challenging. A novel combination of chemical and biological characterization was employed for selection of a representative extract sample used for in vivo investigation of the immunomodulatory properties of Echinace …
Unfortunately, determining risk posed to human health is challenging. A novel combination of chemical and biological characterization …
Sustained mucosal delivery of SAMT-247 via an intravaginal ring reduces the risk of SIVmac251 acquisition in vaccinated macaques.
Rahman MA, Woode EK, Moss JA, Bissa M, Gunawardana M, Gutowska A, Schifanella L, Silva de Castro I, Brown S, Stamos JD, Sarkis S, Robello M, Castonguay AE, Butkyavichene I, Pise-Masison CA, Choo-Wosoba H, Doster M, Alilin AN, Killoran KE, Kramer J, Breed MW, Cardozo T, Appella DH, Baum MM, Franchini G. Rahman MA, et al. Cell Rep Med. 2026 Jun 16:102877. doi: 10.1016/j.xcrm.2026.102877. Online ahead of print. Cell Rep Med. 2026. PMID: 42302793 Free article.
IAN, an intelligent system for omics data analysis and discovery.
Nagarajan V, Horai R, Shi G, Yu CR, Gopalakrishnan J, Yadav MK, Liew MH, Gentilucci C, Caspi RR. Nagarajan V, et al. Cell Rep Methods. 2026 Jun 16:101503. doi: 10.1016/j.crmeth.2026.101503. Online ahead of print. Cell Rep Methods. 2026. PMID: 42302787 Free article.
The IAN package is available at https://github.com/NIH-NEI/IAN....
The IAN package is available at https://github.com/NIH-NEI/IAN....
Concordance Between Bedside and Electronic Detection of Intracranial Pressure Crises: Insights From the Brain Tissue Oxygen Monitoring and Management in Severe Traumatic Brain Injury II Trial.
Chesnut RM, Temkin N, Barber J, Park C, Bonow RH; Brain Tissue Oxygen Monitoring and Management in Severe Traumatic Brain Injury II (BOOST II) Investigators. Chesnut RM, et al. Crit Care Med. 2026 Jun 18. doi: 10.1097/CCM.0000000000007223. Online ahead of print. Crit Care Med. 2026. PMID: 42302399
DESIGN: Post hoc comparison of background-collected continuous E-ICP data to routine B-ICP information during severe TBI management in the Brain Tissue Oxygen Monitoring and Management in Severe TBI (BOOST II) randomized trial. SETTING: Ten U.S. ICUs. PATIENTS: Seve …
DESIGN: Post hoc comparison of background-collected continuous E-ICP data to routine B-ICP information during severe TBI management in the B …
A pooled analysis of phase 2 clinical trials in advanced chordoma.
Cote GM, Elliott CF, Lipplaa A, Gelderblom H, Blay JY, Le Cesne A, Duffaud F, Kesari S, George S, Somaiah N, Conley AP, Teleanu MV, Fröhling S, Schlenk RF, Bompas E, Schuetze SM, Chugh R, Choy E, Chemudupati T, Lozinsky S, Freed DM, Sommer J, Wendelberger B, Stacchiotti S. Cote GM, et al. Eur J Cancer. 2026 Jun 10;244:116875. doi: 10.1016/j.ejca.2026.116875. Online ahead of print. Eur J Cancer. 2026. PMID: 42302352
Development of a Video-Based Decision Aid for Breast Cancer Screening Among Older Women.
Lindsay ME, Odole I, Mohamed S, King C, Schoenborn NL, Schonberg MA, Richman IB. Lindsay ME, et al. J Am Geriatr Soc. 2026 Jun 16. doi: 10.1111/jgs.70526. Online ahead of print. J Am Geriatr Soc. 2026. PMID: 42302231
Decision aids may improve understanding of health information and support informed screening decisions. The goal of this study was to develop a video-based decision aid for breast cancer screening among older women using patient-centered design. ...
Decision aids may improve understanding of health information and support informed screening decisions. The goal of this study was to …
Sleep disturbances during perimenopause and later-life cognitive function.
Hu B, Lin JJ, Qiu X, McAlaine K, Mahalingaiah S, Weisskopf M. Hu B, et al. Menopause. 2026 Jun 16. doi: 10.1097/GME.0000000000002790. Online ahead of print. Menopause. 2026. PMID: 42302113
METHODS: We analyzed 2,097 postmenopausal women without known dementia in the St Louis Baby Tooth-Later Life Health Study (2019-2023). At one postmenopausal visit, participants retrospectively reported perimenopausal sleep, rated current sleep, and completed a cognitive ba …
METHODS: We analyzed 2,097 postmenopausal women without known dementia in the St Louis Baby Tooth-Later Life Health Study (2019-2023) …
DMD-Null mice exhibit severe muscle weakness, impaired regeneration, and deficient satellite cell function.
Wilton-Clark H, Shah MNA, Leckie J, Hernandez Rodriguez S, Al-Aghbari A, Zhabyeyev P, Maruyama R, Aoki Y, Oudit GY, Yokota T. Wilton-Clark H, et al. Proc Natl Acad Sci U S A. 2026 Jun 23;123(25):e2606703123. doi: 10.1073/pnas.2606703123. Epub 2026 Jun 16. Proc Natl Acad Sci U S A. 2026. PMID: 42301789
These findings suggest potential contributions of short dystrophin isoforms to muscle stem cell function, and establish DMD-Null mice as a unique model for investigating the pathogenesis of DMD and testing therapeutic interventions targeting satellite cell health and regen …
These findings suggest potential contributions of short dystrophin isoforms to muscle stem cell function, and establish DMD-Null mice as a u …
Pedagogy and Enriched Environment for Rehabilitation in the HOME After Stroke (PEER-HOMEcare): Study Protocol for a Single-Group Feasibility Study.
Opheim A, Oppici L, Hestetun-Mandrup AM, Sunnerhagen KS, Rafsten L, Bērziņa G, Kārkliņa A, Løvstad M, Øra HP, Marcos L, Pacheco M, Fernandes A, Sørensen L, Rudd JR. Opheim A, et al. Transl Stroke Res. 2026 Jun 16;17(4):68. doi: 10.1007/s12975-026-01459-0. Transl Stroke Res. 2026. PMID: 42301578 Free PMC article.
Neuropathological study of the effects of aducanumab anti-Aβ immunotherapy on patients with Alzheimer's disease.
Welikovitch LA, Oakley DH, Bennett RE, Serrano-Pozo A, Zhu H, Ruiz-Uribe NE, Zwang TJ, Chibnik LB, Gomez-Isla T, Frosch MP, Marks DS, Salloway S, Bernick C, Greeley D, Latimer CS, Nolan A, Hutchison RM, Rubel CE, Bussiere T, Plowey ED, Keene CD, Hyman BT. Welikovitch LA, et al. Acta Neuropathol. 2026 Jun 16;151(1):68. doi: 10.1007/s00401-026-03037-y. Acta Neuropathol. 2026. PMID: 42301522 Free PMC article.
Correction to: Breast cancer survivors' perspectives on a clinical decision tool to support individualized exercise prescriptions and discussions.
Wilson OWA, Wojcik KM, Kerr EM, Rivera I, Tian E, Schneider JD, Brick R, Berrigan D, Tamura K, Rogers LQ, Demark-Wahnefried W, Street RL Jr, Jayasekera J. Wilson OWA, et al. Support Care Cancer. 2026 Jun 16;34(7):662. doi: 10.1007/s00520-026-10899-1. Support Care Cancer. 2026. PMID: 42301493 Free PMC article. No abstract available.
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