Hampton TH - Search Results

1

SARS-CoV-2 (COVID-19) and cystic fibrosis.

Stanton BA, Hampton TH, Ashare A. Stanton BA, et al. Among authors: hampton th. Am J Physiol Lung Cell Mol Physiol. 2020 Sep 1;319(3):L408-L415. doi: 10.1152/ajplung.00225.2020. Epub 2020 Jul 15. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32668165 Free PMC article.

2

A novel approach to analyze gene expression data demonstrates that the DeltaF508 mutation in CFTR downregulates the antigen presentation pathway.

Hampton TH, Stanton BA. Hampton TH, et al. Am J Physiol Lung Cell Mol Physiol. 2010 Apr;298(4):L473-82. doi: 10.1152/ajplung.00379.2009. Epub 2009 Dec 31. Am J Physiol Lung Cell Mol Physiol. 2010. PMID: 20044437 Free PMC article. Review.

3

Iron and CF-related anemia: expanding clinical and biochemical relationships.

Gifford AH, Miller SD, Jackson BP, Hampton TH, O'Toole GA, Stanton BA, Parker HW. Gifford AH, et al. Among authors: hampton th. Pediatr Pulmonol. 2011 Feb;46(2):160-5. doi: 10.1002/ppul.21335. Epub 2010 Oct 20. Pediatr Pulmonol. 2011. PMID: 20963784 Free PMC article.

4

Does the F508-CFTR mutation induce a proinflammatory response in human airway epithelial cells?

Hampton TH, Ballok AE, Bomberger JM, Rutkowski MR, Barnaby R, Coutermarsh B, Conejo-Garcia JR, O'Toole GA, Stanton BA. Hampton TH, et al. Am J Physiol Lung Cell Mol Physiol. 2012 Sep 15;303(6):L509-18. doi: 10.1152/ajplung.00226.2011. Epub 2012 Jul 20. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22821996 Free PMC article.

5

Serial analysis of the gut and respiratory microbiome in cystic fibrosis in infancy: interaction between intestinal and respiratory tracts and impact of nutritional exposures.

Madan JC, Koestler DC, Stanton BA, Davidson L, Moulton LA, Housman ML, Moore JH, Guill MF, Morrison HG, Sogin ML, Hampton TH, Karagas MR, Palumbo PE, Foster JA, Hibberd PL, O'Toole GA. Madan JC, et al. Among authors: hampton th. mBio. 2012 Aug 21;3(4):e00251-12. doi: 10.1128/mBio.00251-12. Print 2012. mBio. 2012. PMID: 22911969 Free PMC article.

6

Anr and its activation by PlcH activity in Pseudomonas aeruginosa host colonization and virulence.

Jackson AA, Gross MJ, Daniels EF, Hampton TH, Hammond JH, Vallet-Gely I, Dove SL, Stanton BA, Hogan DA. Jackson AA, et al. Among authors: hampton th. J Bacteriol. 2013 Jul;195(13):3093-104. doi: 10.1128/JB.02169-12. Epub 2013 May 10. J Bacteriol. 2013. PMID: 23667230 Free PMC article.

7

Iron supplementation does not worsen respiratory health or alter the sputum microbiome in cystic fibrosis.

Gifford AH, Alexandru DM, Li Z, Dorman DB, Moulton LA, Price KE, Hampton TH, Sogin ML, Zuckerman JB, Parker HW, Stanton BA, O'Toole GA. Gifford AH, et al. Among authors: hampton th. J Cyst Fibros. 2014 May;13(3):311-8. doi: 10.1016/j.jcf.2013.11.004. Epub 2013 Dec 13. J Cyst Fibros. 2014. PMID: 24332997 Free PMC article. Clinical Trial.

8

The microbiome in pediatric cystic fibrosis patients: the role of shared environment suggests a window of intervention.

Hampton TH, Green DM, Cutting GR, Morrison HG, Sogin ML, Gifford AH, Stanton BA, O'Toole GA. Hampton TH, et al. Microbiome. 2014 Apr 28;2:14. doi: 10.1186/2049-2618-2-14. eCollection 2014. Microbiome. 2014. PMID: 25071935 Free PMC article.

9

Natural selection canalizes expression variation of environmentally induced plasticity-enabling genes.

Shaw JR, Hampton TH, King BL, Whitehead A, Galvez F, Gross RH, Keith N, Notch E, Jung D, Glaholt SP, Chen CY, Colbourne JK, Stanton BA. Shaw JR, et al. Among authors: hampton th. Mol Biol Evol. 2014 Nov;31(11):3002-15. doi: 10.1093/molbev/msu241. Epub 2014 Aug 25. Mol Biol Evol. 2014. PMID: 25158801 Free PMC article.

10

Characterization and quantification of the fungal microbiome in serial samples from individuals with cystic fibrosis.

Willger SD, Grim SL, Dolben EL, Shipunova A, Hampton TH, Morrison HG, Filkins LM, O'Toole GA, Moulton LA, Ashare A, Sogin ML, Hogan DA. Willger SD, et al. Among authors: hampton th. Microbiome. 2014 Nov 3;2:40. doi: 10.1186/2049-2618-2-40. eCollection 2014. Microbiome. 2014. PMID: 25408892 Free PMC article.

11

Analysis of Lung Microbiota in Bronchoalveolar Lavage, Protected Brush and Sputum Samples from Subjects with Mild-To-Moderate Cystic Fibrosis Lung Disease.

Hogan DA, Willger SD, Dolben EL, Hampton TH, Stanton BA, Morrison HG, Sogin ML, Czum J, Ashare A. Hogan DA, et al. Among authors: hampton th. PLoS One. 2016 Mar 4;11(3):e0149998. doi: 10.1371/journal.pone.0149998. eCollection 2016. PLoS One. 2016. PMID: 26943329 Free PMC article.

12

A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles.

Koeppen K, Hampton TH, Jarek M, Scharfe M, Gerber SA, Mielcarz DW, Demers EG, Dolben EL, Hammond JH, Hogan DA, Stanton BA. Koeppen K, et al. Among authors: hampton th. PLoS Pathog. 2016 Jun 13;12(6):e1005672. doi: 10.1371/journal.ppat.1005672. eCollection 2016 Jun. PLoS Pathog. 2016. PMID: 27295279 Free PMC article.

13

Use of a Multiplex Transcript Method for Analysis of Pseudomonas aeruginosa Gene Expression Profiles in the Cystic Fibrosis Lung.

Gifford AH, Willger SD, Dolben EL, Moulton LA, Dorman DB, Bean H, Hill JE, Hampton TH, Ashare A, Hogan DA. Gifford AH, et al. Among authors: hampton th. Infect Immun. 2016 Sep 19;84(10):2995-3006. doi: 10.1128/IAI.00437-16. Print 2016 Oct. Infect Immun. 2016. PMID: 27481238 Free PMC article.

14

Effectiveness of table top water pitcher filters to remove arsenic from drinking water.

Barnaby R, Liefeld A, Jackson BP, Hampton TH, Stanton BA. Barnaby R, et al. Among authors: hampton th. Environ Res. 2017 Oct;158:610-615. doi: 10.1016/j.envres.2017.07.018. Epub 2017 Jul 15. Environ Res. 2017. PMID: 28719869 Free PMC article.

15

An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung.

Hvorecny KL, Dolben E, Moreau-Marquis S, Hampton TH, Shabaneh TB, Flitter BA, Bahl CD, Bomberger JM, Levy BD, Stanton BA, Hogan DA, Madden DR. Hvorecny KL, et al. Among authors: hampton th. Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L150-L156. doi: 10.1152/ajplung.00383.2017. Epub 2017 Oct 5. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 28982736 Free PMC article.

16

ScanGEO: parallel mining of high-throughput gene expression data.

Koeppen K, Stanton BA, Hampton TH. Koeppen K, et al. Among authors: hampton th. Bioinformatics. 2017 Nov 1;33(21):3500-3501. doi: 10.1093/bioinformatics/btx452. Bioinformatics. 2017. PMID: 29036513 Free PMC article.

17

Lumacaftor (VX-809) restores the ability of CF macrophages to phagocytose and kill Pseudomonas aeruginosa.

Barnaby R, Koeppen K, Nymon A, Hampton TH, Berwin B, Ashare A, Stanton BA. Barnaby R, et al. Among authors: hampton th. Am J Physiol Lung Cell Mol Physiol. 2018 Mar 1;314(3):L432-L438. doi: 10.1152/ajplung.00461.2017. Epub 2017 Nov 16. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29146575 Free PMC article.

18

Arsenic Reduces Gene Expression Response to Changing Salinity in Killifish.

Hampton TH, Jackson C, Jung D, Chen CY, Glaholt SP, Stanton BA, Colbourne JK, Shaw JR. Hampton TH, et al. Environ Sci Technol. 2018 Aug 7;52(15):8811-8821. doi: 10.1021/acs.est.8b01550. Epub 2018 Jul 20. Environ Sci Technol. 2018. PMID: 29979584 Free PMC article.

19

Profiling microRNA expression in Atlantic killifish (Fundulus heteroclitus) gill and responses to arsenic and hyperosmotic stress.

Goodale BC, Hampton TH, Ford EN, Jackson CE, Shaw JR, Stanton BA, King BL. Goodale BC, et al. Among authors: hampton th. Aquat Toxicol. 2019 Jan;206:142-153. doi: 10.1016/j.aquatox.2018.11.009. Epub 2018 Nov 12. Aquat Toxicol. 2019. PMID: 30476744 Free PMC article.

20

Functional and metabolic impairment in cigarette smoke-exposed macrophages is tied to oxidative stress.

Aridgides DS, Mellinger DL, Armstrong DA, Hazlett HF, Dessaint JA, Hampton TH, Atkins GT, Carroll JL, Ashare A. Aridgides DS, et al. Among authors: hampton th. Sci Rep. 2019 Jul 3;9(1):9624. doi: 10.1038/s41598-019-46045-7. Sci Rep. 2019. PMID: 31270372 Free PMC article.

21

Lung function and microbiota diversity in cystic fibrosis.

Cuthbertson L, Walker AW, Oliver AE, Rogers GB, Rivett DW, Hampton TH, Ashare A, Elborn JS, De Soyza A, Carroll MP, Hoffman LR, Lanyon C, Moskowitz SM, O'Toole GA, Parkhill J, Planet PJ, Teneback CC, Tunney MM, Zuckerman JB, Bruce KD, van der Gast CJ. Cuthbertson L, et al. Among authors: hampton th. Microbiome. 2020 Apr 2;8(1):45. doi: 10.1186/s40168-020-00810-3. Microbiome. 2020. PMID: 32238195 Free PMC article.

22

Single-cell RNA-seq Analysis Reveals That Prenatal Arsenic Exposure Results in Long-term, Adverse Effects on Immune Gene Expression in Response to Influenza A Infection.

Hsu KS, Goodale BC, Ely KH, Hampton TH, Stanton BA, Enelow RI. Hsu KS, et al. Among authors: hampton th. Toxicol Sci. 2020 Aug 1;176(2):312-328. doi: 10.1093/toxsci/kfaa080. Toxicol Sci. 2020. PMID: 32514536 Free PMC article.

23

Selection of reference genes for quantitative PCR: identifying reference genes for airway epithelial cells exposed to Pseudomonas aeruginosa.

Hampton TH, Koeppen K, Bashor L, Stanton BA. Hampton TH, et al. Am J Physiol Lung Cell Mol Physiol. 2020 Aug 1;319(2):L256-L265. doi: 10.1152/ajplung.00158.2020. Epub 2020 Jun 10. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32521165 Free PMC article.

24

Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival.

Hazlett HF, Hampton TH, Aridgides DS, Armstrong DA, Dessaint JA, Mellinger DL, Nymon AB, Ashare A. Hazlett HF, et al. Among authors: hampton th. Sci Rep. 2020 Jul 2;10(1):10935. doi: 10.1038/s41598-020-67729-5. Sci Rep. 2020. PMID: 32616918 Free PMC article.

25

Differential effects of the cystic fibrosis lung inflammatory environment on mesenchymal stromal cells.

Abreu SC, Hampton TH, Hoffman E, Dearborn J, Ashare A, Singh Sidhu K, Matthews DE, McKenna DH, Amiel E, Barua J, Krasnodembskaya A, English K, Mahon B, Dos Santos C, Cruz FF, Chambers DC, Liu KD, Matthay MA, Cramer RA, Stanton BA, Rocco PRM, Wargo MJ, Weiss DJ, Rolandsson Enes S. Abreu SC, et al. Among authors: hampton th. Am J Physiol Lung Cell Mol Physiol. 2020 Dec 1;319(6):L908-L925. doi: 10.1152/ajplung.00218.2020. Epub 2020 Sep 9. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32901521 Free PMC article.

26

CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells.

Koeppen K, Nymon A, Barnaby R, Li Z, Hampton TH, Ashare A, Stanton BA. Koeppen K, et al. Among authors: hampton th. Am J Physiol Lung Cell Mol Physiol. 2021 Apr 1;320(4):L530-L544. doi: 10.1152/ajplung.00621.2020. Epub 2021 Jan 20. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33471607 Free PMC article.

27

One versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway.

Jean-Pierre F, Vyas A, Hampton TH, Henson MA, O'Toole GA. Jean-Pierre F, et al. Among authors: hampton th. mBio. 2021 Mar 16;12(2):e00006-21. doi: 10.1128/mBio.00006-21. mBio. 2021. PMID: 33727344 Free PMC article.

28

GAUGE-Annotated Microbial Transcriptomic Data Facilitate Parallel Mining and High-Throughput Reanalysis To Form Data-Driven Hypotheses.

Li Z, Koeppen K, Holden VI, Neff SL, Cengher L, Demers EG, Mould DL, Stanton BA, Hampton TH. Li Z, et al. Among authors: hampton th. mSystems. 2021 Mar 23;6(2):e01305-20. doi: 10.1128/mSystems.01305-20. mSystems. 2021. PMID: 33758032 Free PMC article.

29

Healthy versus inflamed lung environments differentially affect mesenchymal stromal cells.

Rolandsson Enes S, Hampton TH, Barua J, McKenna DH, Dos Santos CC, Amiel E, Ashare A, Liu KD, Krasnodembskaya AD, English K, Stanton BA, Rocco PRM, Matthay MA, Weiss DJ. Rolandsson Enes S, et al. Among authors: hampton th. Eur Respir J. 2021 Oct 14;58(4):2004149. doi: 10.1183/13993003.04149-2020. Print 2021 Oct. Eur Respir J. 2021. PMID: 33795318 Free PMC article.

30

Mild Cystic Fibrosis Lung Disease Is Associated with Bacterial Community Stability.

Hampton TH, Thomas D, van der Gast C, O'Toole GA, Stanton BA. Hampton TH, et al. Microbiol Spectr. 2021 Sep 3;9(1):e0002921. doi: 10.1128/Spectrum.00029-21. Epub 2021 Jul 7. Microbiol Spectr. 2021. PMID: 34232099 Free PMC article.

31

Let-7b-5p in vesicles secreted by human airway cells reduces biofilm formation and increases antibiotic sensitivity of P. aeruginosa.

Koeppen K, Nymon A, Barnaby R, Bashor L, Li Z, Hampton TH, Liefeld AE, Kolling FW, LaCroix IS, Gerber SA, Hogan DA, Kasetty S, Nadell CD, Stanton BA. Koeppen K, et al. Among authors: hampton th. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2105370118. doi: 10.1073/pnas.2105370118. Proc Natl Acad Sci U S A. 2021. PMID: 34260396 Free PMC article.

32

Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions.

O'Toole GA, Crabbé A, Kümmerli R, LiPuma JJ, Bomberger JM, Davies JC, Limoli D, Phelan VV, Bliska JB, DePas WH, Dietrich LE, Hampton TH, Hunter R, Khursigara CM, Price-Whelan A, Ashare A, Cramer RA, Goldberg JB, Harrison F, Hogan DA, Henson MA, Madden DR, Mayers JR, Nadell C, Newman D, Prince A, Rivett DW, Schwartzman JD, Schultz D, Sheppard DC, Smyth AR, Spero MA, Stanton BA, Turner PE, van der Gast C, Whelan FJ, Whitaker R, Whiteson K. O'Toole GA, et al. Among authors: hampton th. mBio. 2021 Oct 26;12(5):e0176321. doi: 10.1128/mBio.01763-21. Epub 2021 Sep 21. mBio. 2021. PMID: 34544277 Free PMC article.

33

CF-Seq, an accessible web application for rapid re-analysis of cystic fibrosis pathogen RNA sequencing studies.

Neff SL, Hampton TH, Puerner C, Cengher L, Doing G, Lee AJ, Koeppen K, Cheung AL, Hogan DA, Cramer RA, Stanton BA. Neff SL, et al. Among authors: hampton th. Sci Data. 2022 Jun 16;9(1):343. doi: 10.1038/s41597-022-01431-1. Sci Data. 2022. PMID: 35710652 Free PMC article.

34

ESKAPE Act Plus: Pathway Activation Analysis for Bacterial Pathogens.

Koeppen K, Hampton TH, Neff SL, Stanton BA. Koeppen K, et al. Among authors: hampton th. mSystems. 2022 Dec 20;7(6):e0046822. doi: 10.1128/msystems.00468-22. Epub 2022 Oct 19. mSystems. 2022. PMID: 36259735 Free PMC article.

35

Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system.

Jean-Pierre F, Hampton TH, Schultz D, Hogan DA, Groleau MC, Déziel E, O'Toole GA. Jean-Pierre F, et al. Among authors: hampton th. Elife. 2023 Jan 20;12:e81604. doi: 10.7554/eLife.81604. Elife. 2023. PMID: 36661299 Free PMC article.

36

An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa.

Koeppen K, Hampton TH, Barnaby R, Roche C, Gerber SA, Goo YA, Cho BK, Vermilyea DM, Hogan DA, Stanton BA. Koeppen K, et al. Among authors: hampton th. Am J Physiol Lung Cell Mol Physiol. 2023 Jul 1;325(1):L54-L65. doi: 10.1152/ajplung.00150.2022. Epub 2023 May 31. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37256658 Free PMC article.

37

Comparative effects of CFTR modulators on phagocytic, metabolic and inflammatory profiles of CF and nonCF macrophages.

Aridgides DS, Mellinger DL, Gwilt LL, Hampton TH, Mould DL, Hogan DA, Ashare A. Aridgides DS, et al. Among authors: hampton th. Sci Rep. 2023 Jul 25;13(1):11995. doi: 10.1038/s41598-023-38300-9. Sci Rep. 2023. PMID: 37491532 Free PMC article.

38

Rocket-miR, a translational launchpad for miRNA-based antimicrobial drug development.

Neff SL, Hampton TH, Koeppen K, Sarkar S, Latario CJ, Ross BD, Stanton BA. Neff SL, et al. Among authors: hampton th. mSystems. 2023 Dec 21;8(6):e0065323. doi: 10.1128/msystems.00653-23. Epub 2023 Nov 17. mSystems. 2023. PMID: 37975659 Free PMC article.

39

APPLICATION OF QUANTILE DISCRETIZATION AND BAYESIAN NETWORK ANALYSIS TO PUBLICLY AVAILABLE CYSTIC FIBROSIS DATA SETS.

Fukutani KF, Hampton TH, Bobak CA, MacKenzie TA, Stanton BA. Fukutani KF, et al. Among authors: hampton th. Pac Symp Biocomput. 2024;29:534-548. Pac Symp Biocomput. 2024. PMID: 38160305 Free PMC article.

40

P. aeruginosa tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in cystic fibrosis.

Li Z, Barnaby R, Nymon A, Roche C, Koeppen K, Ashare A, Hogan DA, Gerber SA, Taatjes DJ, Hampton TH, Stanton BA. Li Z, et al. Among authors: hampton th. Am J Physiol Lung Cell Mol Physiol. 2024 May 1;326(5):L574-L588. doi: 10.1152/ajplung.00018.2024. Epub 2024 Mar 5. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 38440830 Free article.

41

Prevalence of streptococci and increased polymicrobial diversity associated with cystic fibrosis patient stability.

Filkins LM, Hampton TH, Gifford AH, Gross MJ, Hogan DA, Sogin ML, Morrison HG, Paster BJ, O'Toole GA. Filkins LM, et al. Among authors: hampton th. J Bacteriol. 2012 Sep;194(17):4709-17. doi: 10.1128/JB.00566-12. Epub 2012 Jun 29. J Bacteriol. 2012. PMID: 22753064 Free PMC article.

42

Unique microbial communities persist in individual cystic fibrosis patients throughout a clinical exacerbation.

Price KE, Hampton TH, Gifford AH, Dolben EL, Hogan DA, Morrison HG, Sogin ML, O'Toole GA. Price KE, et al. Among authors: hampton th. Microbiome. 2013 Nov 1;1(1):27. doi: 10.1186/2049-2618-1-27. Microbiome. 2013. PMID: 24451123 Free PMC article.

43

Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators.

Flitter BA, Hvorecny KL, Ono E, Eddens T, Yang J, Kwak DH, Bahl CD, Hampton TH, Morisseau C, Hammock BD, Liu X, Lee JS, Kolls JK, Levy BD, Madden DR, Bomberger JM. Flitter BA, et al. Among authors: hampton th. Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):136-141. doi: 10.1073/pnas.1610242114. Epub 2016 Dec 15. Proc Natl Acad Sci U S A. 2017. PMID: 27980032 Free PMC article.

44

The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection.

Loeven NA, Perault AI, Cotter PA, Hodges CA, Schwartzman JD, Hampton TH, Bliska JB. Loeven NA, et al. Among authors: hampton th. mBio. 2021 Oct 26;12(5):e0209821. doi: 10.1128/mBio.02098-21. Epub 2021 Sep 28. mBio. 2021. PMID: 34579569 Free PMC article.

45

Development of the intestinal microbiome in cystic fibrosis in early life.

Price CE, Hampton TH, Valls RA, Barrack KE, O'Toole GA, Madan JC, Coker MO. Price CE, et al. Among authors: hampton th. mSphere. 2023 Aug 24;8(4):e0004623. doi: 10.1128/msphere.00046-23. Epub 2023 Jul 5. mSphere. 2023. PMID: 37404016 Free PMC article.

46

An In Vitro Medium for Modeling Gut Dysbiosis Associated with Cystic Fibrosis.

Barrack KE, Hampton TH, Valls RA, Surve SV, Gardner TB, Sanville JL, Madan JC, O'Toole GA. Barrack KE, et al. Among authors: hampton th. bioRxiv [Preprint]. 2023 Aug 2:2023.08.01.551570. doi: 10.1101/2023.08.01.551570. bioRxiv. 2023. PMID: 37577487 Free PMC article. Updated. Preprint.

47

Analysis of Pseudomonas aeruginosa transcription in an ex vivo cystic fibrosis sputum model identifies metal restriction as a gene expression stimulus.

Neff SL, Doing G, Reiter T, Hampton TH, Greene CS, Hogan DA. Neff SL, et al. Among authors: hampton th. bioRxiv [Preprint]. 2023 Aug 21:2023.08.21.554169. doi: 10.1101/2023.08.21.554169. bioRxiv. 2023. PMID: 37662412 Free PMC article. Preprint.

48

An in vitro medium for modeling gut dysbiosis associated with cystic fibrosis.

Barrack KE, Hampton TH, Valls RA, Surve SV, Gardner TB, Sanville JL, Madan JL, O'Toole GA. Barrack KE, et al. Among authors: hampton th. J Bacteriol. 2024 Jan 25;206(1):e0028623. doi: 10.1128/jb.00286-23. Epub 2024 Jan 3. J Bacteriol. 2024. PMID: 38169295 Free PMC article.

49

Pseudomonas aeruginosa transcriptome analysis of metal restriction in ex vivo cystic fibrosis sputum.

Neff SL, Doing G, Reiter T, Hampton TH, Greene CS, Hogan DA. Neff SL, et al. Among authors: hampton th. Microbiol Spectr. 2024 Apr 2;12(4):e0315723. doi: 10.1128/spectrum.03157-23. Epub 2024 Feb 22. Microbiol Spectr. 2024. PMID: 38385740 Free article.

50

Availability of Zinc Impacts Interactions between Streptococcus sanguinis and Pseudomonas aeruginosa in Coculture.

Li K, Gifford AH, Hampton TH, O'Toole GA. Li K, et al. Among authors: hampton th. J Bacteriol. 2020 Jan 2;202(2):e00618-19. doi: 10.1128/JB.00618-19. Print 2020 Jan 2. J Bacteriol. 2020. PMID: 31685535 Free PMC article.

51

Gene response profiles for Daphnia pulex exposed to the environmental stressor cadmium reveals novel crustacean metallothioneins.

Shaw JR, Colbourne JK, Davey JC, Glaholt SP, Hampton TH, Chen CY, Folt CL, Hamilton JW. Shaw JR, et al. Among authors: hampton th. BMC Genomics. 2007 Dec 21;8:477. doi: 10.1186/1471-2164-8-477. BMC Genomics. 2007. PMID: 18154678 Free PMC article.

52

Laboratory diet profoundly alters gene expression and confounds genomic analysis in mouse liver and lung.

Kozul CD, Nomikos AP, Hampton TH, Warnke LA, Gosse JA, Davey JC, Thorpe JE, Jackson BP, Ihnat MA, Hamilton JW. Kozul CD, et al. Among authors: hampton th. Chem Biol Interact. 2008 May 28;173(2):129-40. doi: 10.1016/j.cbi.2008.02.008. Epub 2008 Mar 4. Chem Biol Interact. 2008. PMID: 18396267

53

2-Heptyl-4-quinolone, a precursor of the Pseudomonas quinolone signal molecule, modulates swarming motility in Pseudomonas aeruginosa.

Ha DG, Merritt JH, Hampton TH, Hodgkinson JT, Janecek M, Spring DR, Welch M, O'Toole GA. Ha DG, et al. Among authors: hampton th. J Bacteriol. 2011 Dec;193(23):6770-80. doi: 10.1128/JB.05929-11. Epub 2011 Sep 30. J Bacteriol. 2011. PMID: 21965567 Free PMC article.

54

The microbiota regulates susceptibility to Fas-mediated acute hepatic injury.

Celaj S, Gleeson MW, Deng J, O'Toole GA, Hampton TH, Toft MF, Morrison HG, Sogin ML, Putra J, Suriawinata AA, Gorham JD. Celaj S, et al. Among authors: hampton th. Lab Invest. 2014 Sep;94(9):938-49. doi: 10.1038/labinvest.2014.93. Epub 2014 Jul 28. Lab Invest. 2014. PMID: 25068658 Free PMC article.

55

The mitogen-activated protein kinase pathway plays a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells.

Whipple CA, Boni A, Fisher JL, Hampton TH, Tsongalis GJ, Mellinger DL, Yan S, Tafe LJ, Brinckerhoff CE, Turk MJ, Mullins DW, Fadul CE, Ernstoff MS. Whipple CA, et al. Among authors: hampton th. Melanoma Res. 2016 Jun;26(3):223-35. doi: 10.1097/CMR.0000000000000244. Melanoma Res. 2016. PMID: 26974965

56

The landscape of extreme genomic variation in the highly adaptable Atlantic killifish.

Reid NM, Jackson CE, Gilbert D, Minx P, Montague MJ, Hampton TH, Helfrich LW, King BL, Nacci DE, Aluru N, Karchner SI, Colbourne JK, Hahn ME, Shaw JR, Oleksiak MF, Crawford DL, Warren WC, Whitehead A. Reid NM, et al. Among authors: hampton th. Genome Biol Evol. 2017 Mar;9(3):659-676. doi: 10.1093/gbe/evx023. Epub 2017 Feb 13. Genome Biol Evol. 2017. PMID: 28201664 Free PMC article.

57

Perturbation of defense pathways by low-dose arsenic exposure in zebrafish embryos.

Mattingly CJ, Hampton TH, Brothers KM, Griffin NE, Planchart A. Mattingly CJ, et al. Among authors: hampton th. Environ Health Perspect. 2009 Jun;117(6):981-7. doi: 10.1289/ehp.0900555. Epub 2009 Feb 22. Environ Health Perspect. 2009. PMID: 19590694 Free PMC article.

58

Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung.

Kozul CD, Hampton TH, Davey JC, Gosse JA, Nomikos AP, Eisenhauer PL, Weiss DJ, Thorpe JE, Ihnat MA, Hamilton JW. Kozul CD, et al. Among authors: hampton th. Environ Health Perspect. 2009 Jul;117(7):1108-15. doi: 10.1289/ehp.0800199. Epub 2009 Mar 4. Environ Health Perspect. 2009. PMID: 19654921 Free PMC article.

59

Regulatory T-cells and associated pathways in metastatic renal cell carcinoma (mRCC) patients undergoing DC-vaccination and cytokine-therapy.

Schwarzer A, Wolf B, Fisher JL, Schwaab T, Olek S, Baron U, Tomlinson CR, Seigne JD, Crosby NA, Gui J, Hampton TH, Fadul CE, Heaney JA, Ernstoff MS. Schwarzer A, et al. Among authors: hampton th. PLoS One. 2012;7(10):e46600. doi: 10.1371/journal.pone.0046600. Epub 2012 Oct 31. PLoS One. 2012. PMID: 23118856 Free PMC article.

60

Gene expression profile of peripheral blood lymphocytes from renal cell carcinoma patients treated with IL-2, interferon-α and dendritic cell vaccine.

Wolf B, Schwarzer A, Côté AL, Hampton TH, Schwaab T, Huarte E, Tomlinson CR, Gui J, Fisher JL, Fadul CE, Hamilton JW, Ernstoff MS. Wolf B, et al. Among authors: hampton th. PLoS One. 2012;7(12):e50221. doi: 10.1371/journal.pone.0050221. Epub 2012 Dec 3. PLoS One. 2012. PMID: 23226513 Free PMC article.

61

Pseudomonas aeruginosa lasR mutant fitness in microoxia is supported by an Anr-regulated oxygen-binding hemerythrin.

Clay ME, Hammond JH, Zhong F, Chen X, Kowalski CH, Lee AJ, Porter MS, Hampton TH, Greene CS, Pletneva EV, Hogan DA. Clay ME, et al. Among authors: hampton th. Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):3167-3173. doi: 10.1073/pnas.1917576117. Epub 2020 Jan 24. Proc Natl Acad Sci U S A. 2020. PMID: 31980538 Free PMC article.

62

Specificity in PDZ-peptide interaction networks: Computational analysis and review.

Amacher JF, Brooks L, Hampton TH, Madden DR. Amacher JF, et al. Among authors: hampton th. J Struct Biol X. 2020;4:100022. doi: 10.1016/j.yjsbx.2020.100022. Epub 2020 Mar 7. J Struct Biol X. 2020. PMID: 32289118 Free PMC article. Review.

63

Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10.

Sheehan CT, Hampton TH, Madden DR. Sheehan CT, et al. Among authors: hampton th. J Biol Chem. 2022 Dec;298(12):102552. doi: 10.1016/j.jbc.2022.102552. Epub 2022 Sep 29. J Biol Chem. 2022. PMID: 36183834 Free PMC article.

64

GeneComps and ChemComps: a new CTD metric to identify genes and chemicals with shared toxicogenomic profiles.

Davis AP, Murphy CG, Saraceni-Richards CA, Rosenstein MC, Wiegers TC, Hampton TH, Mattingly CJ. Davis AP, et al. Among authors: hampton th. Bioinformation. 2009 Oct 15;4(4):173-4. doi: 10.6026/97320630004173. Bioinformation. 2009. PMID: 20198196 Free PMC article.

65

Regulatory T cells are not a strong predictor of survival for patients with glioblastoma.

Thomas AA, Fisher JL, Rahme GJ, Hampton TH, Baron U, Olek S, Schwachula T, Rhodes CH, Gui J, Tafe LJ, Tsongalis GJ, Lefferts JA, Wishart H, Kleen J, Miller M, Whipple CA, de Abreu FB, Ernstoff MS, Fadul CE. Thomas AA, et al. Among authors: hampton th. Neuro Oncol. 2015 Jun;17(6):801-9. doi: 10.1093/neuonc/nou363. Epub 2015 Jan 24. Neuro Oncol. 2015. PMID: 25618892 Free PMC article.

66

Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme.

Fadul CE, Fisher JL, Gui J, Hampton TH, Côté AL, Ernstoff MS. Fadul CE, et al. Among authors: hampton th. Neuro Oncol. 2011 Apr;13(4):393-400. doi: 10.1093/neuonc/noq204. Epub 2011 Feb 20. Neuro Oncol. 2011. PMID: 21339188 Free PMC article.

67

Immune response in patients with newly diagnosed glioblastoma multiforme treated with intranodal autologous tumor lysate-dendritic cell vaccination after radiation chemotherapy.

Fadul CE, Fisher JL, Hampton TH, Lallana EC, Li Z, Gui J, Szczepiorkowski ZM, Tosteson TD, Rhodes CH, Wishart HA, Lewis LD, Ernstoff MS. Fadul CE, et al. Among authors: hampton th. J Immunother. 2011 May;34(4):382-9. doi: 10.1097/CJI.0b013e318215e300. J Immunother. 2011. PMID: 21499132 Free PMC article. Clinical Trial.

68

Letter to the editor.

Fadul CE, Fisher JL, Hampton TH, Ernstoff MS. Fadul CE, et al. Among authors: hampton th. J Immunother Cancer. 2014 Jul 15;2:22. doi: 10.1186/2051-1426-2-22. eCollection 2014. J Immunother Cancer. 2014. PMID: 25097758 Free PMC article. No abstract available.

69

Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma.

Thomas AA, Fisher JL, Hampton TH, Christensen BC, Tsongalis GJ, Rahme GJ, Whipple CA, Steel SE, Davis MC, Gaur AB, Lewis LD, Ernstoff MS, Fadul CE. Thomas AA, et al. Among authors: hampton th. Cancer Immunol Immunother. 2017 Mar;66(3):379-389. doi: 10.1007/s00262-016-1941-3. Epub 2016 Dec 9. Cancer Immunol Immunother. 2017. PMID: 27942839

70

CAS12e (CASX2) CLEAVAGE OF CCR5: IMPACT OF GUIDE RNA LENGTH AND PAM SEQUENCE ON CLEAVAGE ACTIVITY.

Armstrong DA, Hudson TR, Hodge CA, Hampton TH, Howell AL, Hayden MS. Armstrong DA, et al. Among authors: hampton th. bioRxiv [Preprint]. 2023 Jan 2:2023.01.02.522476. doi: 10.1101/2023.01.02.522476. bioRxiv. 2023. PMID: 36711562 Free PMC article. Updated. Preprint.

71

PlmCas12e (CasX2) cleavage of CCR5: impact of guide RNA spacer length and PAM sequence on cleavage activity.

Armstrong DA, Hudson TR, Hodge CA, Hampton TH, Howell AL, Hayden MS. Armstrong DA, et al. Among authors: hampton th. RNA Biol. 2023 Jan;20(1):296-305. doi: 10.1080/15476286.2023.2221510. RNA Biol. 2023. PMID: 37287312 Free PMC article.

72

The carcinogen chromate induces DNA cross-links in rat liver and kidney.

Tsapakos MJ, Hampton TH, Jennette KW. Tsapakos MJ, et al. Among authors: hampton th. J Biol Chem. 1981 Apr 25;256(8):3623-6. J Biol Chem. 1981. PMID: 7217049 Free article.

73

Chromium(VI)-induced DNA lesions and chromium distribution in rat kidney, liver, and lung.

Tsapakos MJ, Hampton TH, Wetterhahn KE. Tsapakos MJ, et al. Among authors: hampton th. Cancer Res. 1983 Dec;43(12 Pt 1):5662-7. Cancer Res. 1983. PMID: 6640521

74

The carcinogen chromate causes DNA damage and inhibits drug-mediated induction of porphyrin accumulation and glucuronidation in chick embryo hepatocytes.

Tsapakos MJ, Hampton TH, Sinclair PR, Sinclair JF, Bement WJ, Wetterhahn KE. Tsapakos MJ, et al. Among authors: hampton th. Carcinogenesis. 1983 Aug;4(8):959-66. doi: 10.1093/carcin/4.8.959. Carcinogenesis. 1983. PMID: 6872154

75

Nickel carbonate induces DNA-protein crosslinks and DNA strand breaks in rat kidney.

Ciccarelli RB, Hampton TH, Jennette KW. Ciccarelli RB, et al. Among authors: hampton th. Cancer Lett. 1981 May;12(4):349-54. doi: 10.1016/0304-3835(81)90178-6. Cancer Lett. 1981. PMID: 7306939

76

P. aeruginosa tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in Cystic Fibrosis.

Li Z, Barnaby R, Nymon A, Roche C, Koeppen K, Ashare A, Hogan DA, Gerber SA, Taatjes DJ, Hampton TH, Stanton BA. Li Z, et al. Among authors: hampton th. bioRxiv [Preprint]. 2024 Feb 3:2024.02.03.578737. doi: 10.1101/2024.02.03.578737. bioRxiv. 2024. PMID: 38352468 Free PMC article. Updated. Preprint.

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