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Page 1
Inflammation Associated With Obesity, Aging, and Amyloid Burden in Adults With Down Syndrome.
Fleming-Batayneh VL, Helsel BC, Ptomey LT, Handen BL, Mapstone M, Petersen M, Krinsky-McHale SJ, Hom CL, Minhas D, Luo W, Laymon C, Lee JH, Cohen A, Ances BM, Brickman AM, Pulsifer M, Rosas HD, Lai F, Zaman SH, Head E, Tudorascu D, Price J, Schmitt F, Christian BT, Okonkwo O, Hartley SL; Alzheimer Biomarkers Consortium‐Down Syndrome (ABC‐DS) Investigators. Fleming-Batayneh VL, et al. Obesity (Silver Spring). 2026 Jun 5. doi: 10.1002/oby.70229. Online ahead of print. Obesity (Silver Spring). 2026. PMID: 42244445
The impact of congenital heart disease on the timing of Alzheimer's disease in Down syndrome.
Clina JG, Helsel BC, Hartley SL, White DA, Fleming-Batayneh VL, Handen B, Christian B, Head E, Mapstone M, Hom CL, Ances B, Burns J, Rosas HD, Lai F, McHale SK, Lee JH, Schmitt FA, Harp J, Lott IT, Zaman S, Ptomey LT; Alzheimer Biomarker Consortium–Down Syndrome (ABC‐DS) Investigators. Clina JG, et al. Alzheimers Dement (Amst). 2026 Jan 18;18(1):e70257. doi: 10.1002/dad2.70257. eCollection 2026 Jan-Mar. Alzheimers Dement (Amst). 2026. PMID: 41561734 Free PMC article.
The joint association of obesity and physical activity on cognitive function in Down syndrome.
Clina JG, Helsel BC, Hartley SL, Fleming-Batayneh VL, Handen B, Christian B, Head E, Mapstone M, Hom CL, Burns J, Ances B, Ptomey LT; Alzheimer Biomarker Consortium–Down Syndrome (ABC-DS) Investigators. Clina JG, et al. J Alzheimers Dis. 2025 Dec;108(3):1328-1338. doi: 10.1177/13872877251386474. Epub 2025 Oct 16. J Alzheimers Dis. 2025. PMID: 41100837 Free PMC article.
Physical activity as a resistance or resilience mechanism in Down syndrome Alzheimer's disease.
Fleming VL, Peven J, Helsel BC, Ptomey LT, Clina J, Barry A, Ances BM, Handen BL, Christian BT, Laymon C, Zammit M, Head E, Mapstone M, Okonkwo O, Hartley SL; Alzheimer Biomarkers Consortium – Down Syndrome. Fleming VL, et al. Alzheimers Dement (N Y). 2025 Jun 27;11(3):e70127. doi: 10.1002/trc2.70127. eCollection 2025 Jul-Sep. Alzheimers Dement (N Y). 2025. PMID: 40584896 Free PMC article.
Longitudinal study of body mass index in relation to Alzheimer's disease pathology and symptomatology in Down syndrome.
Fleming VL, Helsel BC, Ptomey LT, Handen BL, Krinsky-McHale SJ, Hom CL, Zammit M, Minhas D, Luo W, Laymon C, Lee JH, Lott I, Cohen A, Ances BM, Brickman AM, Pulsifer M, Clare ICH, Rosa HD, Lai F, Harp J, Schmitt F, Price J, Zaman SH, Head E, Mapstone M, Christian BT, Okonkwo O, Hartley SL; Alzheimer's Biomarkers Consortium–Down Syndrome. Fleming VL, et al. Alzheimers Dement. 2025 Jun;21(6):e70387. doi: 10.1002/alz.70387. Alzheimers Dement. 2025. PMID: 40545561 Free PMC article.
The promotion of physical activity for use in Alzheimer's disease prevention trials in adults with Down syndrome: Results from a 12-month randomized trial.
Ptomey LT, Helsel BC, Washburn RA, Montgomery RN, Krebill R, Danon JC, Sherman JR, Forsha D, Bodde A, Szabo-Reed AN, Gorczyca AM, Donnelly JE. Ptomey LT, et al. Alzheimers Dement (N Y). 2025 Jun 12;11(2):e70115. doi: 10.1002/trc2.70115. eCollection 2025 Apr-Jun. Alzheimers Dement (N Y). 2025. PMID: 40520478 Free PMC article.