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Page 1
Cell-drug conjugates.
Wang Y, Shi J, Xin M, Kahkoska AR, Wang J, Gu Z. Wang Y, et al. Nat Biomed Eng. 2024 Nov;8(11):1347-1365. doi: 10.1038/s41551-024-01230-6. Epub 2024 Jul 1. Nat Biomed Eng. 2024. PMID: 38951139 Review.
Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.
Jiang MZ, Gaynor SM, Li X, Van Buren E, Stilp A, Buth E, Wang FF, Manansala R, Gogarten SM, Li Z, Polfus LM, Salimi S, Bis JC, Pankratz N, Yanek LR, Durda P, Tracy RP, Rich SS, Rotter JI, Mitchell BD, Lewis JP, Psaty BM, Pratte KA, Silverman EK, Kaplan RC, Avery C, North KE, Mathias RA, Faraday N, Lin H, Wang B, Carson AP, Norwood AF, Gibbs RA, Kooperberg C, Lundin J, Peters U, Dupuis J, Hou L, Fornage M, Benjamin EJ, Reiner AP, Bowler RP, Lin X, Auer PL, Raffield LM; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Inflammation Working Group. Jiang MZ, et al. Hum Mol Genet. 2024 Aug 6;33(16):1429-1441. doi: 10.1093/hmg/ddae050. Hum Mol Genet. 2024. PMID: 38747556
The Surprising Effect of Priming on SNOT-22 Results.
Mohammad I, Stack T, Norris M, Kim S, Lamb M, Thorp BD, Klatt-Cromwell C, Ebert CS Jr, Kimple AJ, Senior BA. Mohammad I, et al. Am J Rhinol Allergy. 2024 May;38(3):153-158. doi: 10.1177/19458924241229160. Epub 2024 Feb 8. Am J Rhinol Allergy. 2024. PMID: 38332587 Free PMC article. Clinical Trial.
Machine Learning and Health Science Research: Tutorial.
Cho H, She J, De Marchi D, El-Zaatari H, Barnes EL, Kahkoska AR, Kosorok MR, Virkud AV. Cho H, et al. J Med Internet Res. 2024 Jan 30;26:e50890. doi: 10.2196/50890. J Med Internet Res. 2024. PMID: 38289657 Free PMC article.
Characterizing Adverse Events of Biologic Treatment of T2 Disease: A Disproportionality Analysis of the FDA Adverse Event Reporting System.
Stack TJ, Kim S, Lamb MM, Mohammad I, Zeatoun A, Lopez E, Klatt-Cromwell C, Thorp BD, Ebert CS Jr, Senior BA, Kimple AJ, Alicea D. Stack TJ, et al. ORL J Otorhinolaryngol Relat Spec. 2023;85(6):329-339. doi: 10.1159/000534545. Epub 2023 Nov 14. ORL J Otorhinolaryngol Relat Spec. 2023. PMID: 37963438 Free PMC article.
Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk.
Liu X, Sun X, Zhang Y, Jiang W, Lai M, Wiggins KL, Raffield LM, Bielak LF, Zhao W, Pitsillides A, Haessler J, Zheng Y, Blackwell TW, Yao J, Guo X, Qian Y, Thyagarajan B, Pankratz N, Rich SS, Taylor KD, Peyser PA, Heckbert SR, Seshadri S, Boerwinkle E, Grove ML, Larson NB, Smith JA, Vasan RS, Fitzpatrick AL, Fornage M, Ding J, Carson AP, Abecasis G, Dupuis J, Reiner A, Kooperberg C, Hou L, Psaty BM, Wilson JG, Levy D, Rotter JI, Bis JC; TOPMed mtDNA Working Group in NHLBI Trans‐Omics for Precision Medicine (TOPMed) Consortium; Satizabal CL, Arking DE, Liu C. Liu X, et al. J Am Heart Assoc. 2023 Oct 17;12(20):e029090. doi: 10.1161/JAHA.122.029090. Epub 2023 Oct 7. J Am Heart Assoc. 2023. PMID: 37804200 Free PMC article.
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine.
Tobias DK, Merino J, Ahmad A, Aiken C, Benham JL, Bodhini D, Clark AL, Colclough K, Corcoy R, Cromer SJ, Duan D, Felton JL, Francis EC, Gillard P, Gingras V, Gaillard R, Haider E, Hughes A, Ikle JM, Jacobsen LM, Kahkoska AR, Kettunen JLT, Kreienkamp RJ, Lim LL, Männistö JME, Massey R, Mclennan NM, Miller RG, Morieri ML, Most J, Naylor RN, Ozkan B, Patel KA, Pilla SJ, Prystupa K, Raghavan S, Rooney MR, Schön M, Semnani-Azad Z, Sevilla-Gonzalez M, Svalastoga P, Takele WW, Tam CH, Thuesen ACB, Tosur M, Wallace AS, Wang CC, Wong JJ, Yamamoto JM, Young K, Amouyal C, Andersen MK, Bonham MP, Chen M, Cheng F, Chikowore T, Chivers SC, Clemmensen C, Dabelea D, Dawed AY, Deutsch AJ, Dickens LT, DiMeglio LA, Dudenhöffer-Pfeifer M, Evans-Molina C, Fernández-Balsells MM, Fitipaldi H, Fitzpatrick SL, Gitelman SE, Goodarzi MO, Grieger JA, Guasch-Ferré M, Habibi N, Hansen T, Huang C, Harris-Kawano A, Ismail HM, Hoag B, Johnson RK, Jones AG, Koivula RW, Leong A, Leung GKW, Libman IM, Liu K, Long SA, Lowe WL Jr, Morton RW, Motala AA, Onengut-Gumuscu S, Pankow JS, Pathirana M, Pazmino S, Perez D, Petrie JR, Powe CE, Quinteros A, Jain R, Ray D, Ried-Larsen M, Saeed Z, Santhakumar V, Kanbour S, Sarkar … See abstract for full author list ➔ Tobias DK, et al. Nat Med. 2023 Oct;29(10):2438-2457. doi: 10.1038/s41591-023-02502-5. Epub 2023 Oct 5. Nat Med. 2023. PMID: 37794253 Free PMC article. Review.
Whole Genome Sequencing Based Analysis of Inflammation Biomarkers in the Trans-Omics for Precision Medicine (TOPMed) Consortium.
Jiang MZ, Gaynor SM, Li X, Van Buren E, Stilp A, Buth E, Wang FF, Manansala R, Gogarten SM, Li Z, Polfus LM, Salimi S, Bis JC, Pankratz N, Yanek LR, Durda P, Tracy RP, Rich SS, Rotter JI, Mitchell BD, Lewis JP, Psaty BM, Pratte KA, Silverman EK, Kaplan RC, Avery C, North K, Mathias RA, Faraday N, Lin H, Wang B, Carson AP, Norwood AF, Gibbs RA, Kooperberg C, Lundin J, Peters U, Dupuis J, Hou L, Fornage M, Benjamin EJ, Reiner AP, Bowler RP, Lin X, Auer PL, Raffield LM; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Inflammation Working Group. Jiang MZ, et al. bioRxiv [Preprint]. 2023 Sep 12:2023.09.10.555215. doi: 10.1101/2023.09.10.555215. bioRxiv. 2023. Update in: Hum Mol Genet. 2024 Aug 6;33(16):1429-1441. doi: 10.1093/hmg/ddae050 PMID: 37745480 Free PMC article. Updated. Preprint.
WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.
Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier K, Chittoor G, Josyula NS, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, Carlson CS, Chang KM, Chavan S, Chiu YF, Chuang LM, Conomos MP, DeMeo DL, Du M, Duggirala R, Eng C, Fohner AE, Freedman BI, Garrett ME, Guo X, Haiman C, Heavner BD, Hidalgo B, Hixson JE, Ho YL, Hobbs BD, Hu D, Hui Q, Hwu CM, Jackson RD, Jain D, Kalyani RR, Kardia SLR, Kelly TN, Lange EM, LeNoir M, Li C, Marchand LL, McDonald MN, McHugh CP, Morrison AC, Naseri T; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; O'Connell J, O'Donnell CJ, Palmer ND, Pankow JS, Perry JA, Peters U, Preuss MH, Rao DC, Regan EA, Reupena SM, Roden DM, Rodriguez-Santana J, Sitlani CM, Smith JA, Tiwari HK, Vasan RS, Wang Z, Weeks DE, Wessel J, Wiggins KL, Wilkens LR, Wilson PWF, Yanek LR, Yoneda ZT, Zhao W, Zöllner S, Arnett DK, Ashley-Koch AE, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Carson AP, Chasman DI, Chen YI, Curran JE, Fornage M, Gordeuk VR, He J, Heckbert SR, Hou L, Irvin MR, Kooperberg C, Minster RL, Mitchell BD, Nouraie M, Psaty BM, Raffield LM, Reiner AP, Rich SS, Rotter JI, Shoe… See abstract for full author list ➔ Zhang X, et al. medRxiv [Preprint]. 2023 Aug 22:2023.08.21.23293271. doi: 10.1101/2023.08.21.23293271. medRxiv. 2023. PMID: 37662265 Free PMC article. Preprint.
Ancestral diversity in lipoprotein(a) studies helps address evidence gaps.
Lee MP, Dimos SF, Raffield LM, Wang Z, Ballou AF, Downie CG, Arehart CH, Correa A, de Vries PS, Du Z, Gignoux CR, Gordon-Larsen P, Guo X, Haessler J, Howard AG, Hu Y, Kassahun H, Kent ST, Lopez JAG, Monda KL, North KE, Peters U, Preuss MH, Rich SS, Rhodes SL, Yao J, Yarosh R, Tsai MY, Rotter JI, Kooperberg CL, Loos RJF, Ballantyne C, Avery CL, Graff M. Lee MP, et al. Open Heart. 2023 Aug;10(2):e002382. doi: 10.1136/openhrt-2023-002382. Open Heart. 2023. PMID: 37648373 Free PMC article.
Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk.
Georgakis MK, Malik R, El Bounkari O, Hasbani NR, Li J, Huffman JE, Shakt G, Tack RWP, Kimball TN, Asare Y, Morrison AC, Tsao NL, Judy R, Mitchell BD, Xu H, Montasser ME, Do R, Kenny EE, Loos RJF, Terry JG, Carr JJ, Bis JC, Psaty BM, Longstreth WT, Young KA, Lutz SM, Cho MH, Broome J, Khan AT, Wang FF, Heard-Costa N, Seshadri S, Vasan RS, Palmer ND, Freedman BI, Bowden DW, Yanek LR, Kral BG, Becker LC, Peyser PA, Bielak LF, Ammous F, Carson AP, Hall ME, Raffield LM, Rich SS, Post WS, Tracy RP, Taylor KD, Guo X, Mahaney MC, Curran JE, Blangero J, Clarke SL, Haessler JW, Hu Y, Assimes TL, Kooperberg C, Bernhagen J, Anderson CD, Damrauer SM, Zand R, Rotter JI, de Vries PS, Dichgans M. Georgakis MK, et al. medRxiv [Preprint]. 2024 Jun 26:2023.08.14.23294063. doi: 10.1101/2023.08.14.23294063. medRxiv. 2024. PMID: 37645892 Free PMC article. Preprint.
Genetic examination of hematological parameters in SARS-CoV-2 infection and COVID-19.
Sun Q, Rowland B, Wang W, Miller-Fleming TW, Cox N, Graff M, Faucon A, Shuey MM, Blue EE, Auer P, Li Y, Sankaran VG, Reiner AP, Raffield LM. Sun Q, et al. Blood Cells Mol Dis. 2023 Nov;103:102782. doi: 10.1016/j.bcmd.2023.102782. Epub 2023 Jul 20. Blood Cells Mol Dis. 2023. PMID: 37558590 Free PMC article.
The Growing Role of Technology in the Care of Older Adults With Diabetes.
Huang ES, Sinclair A, Conlin PR, Cukierman-Yaffe T, Hirsch IB, Huisingh-Scheetz M, Kahkoska AR, Laffel L, Lee AK, Lee S, Lipska K, Meneilly G, Pandya N, Peek ME, Peters A, Pratley RE, Sherifali D, Toschi E, Umpierrez G, Weinstock RS, Munshi M. Huang ES, et al. Diabetes Care. 2023 Aug 1;46(8):1455-1463. doi: 10.2337/dci23-0021. Diabetes Care. 2023. PMID: 37471606 Free PMC article. Review.
An epidemiological introduction to human metabolomic investigations.
Joshi AD, Rahnavard A, Kachroo P, Mendez KM, Lawrence W, Julián-Serrano S, Hua X, Fuller H, Sinnott-Armstrong N, Tabung FK, Shutta KH, Raffield LM, Darst BF; COMETS Early Career Scientist Working Group. Joshi AD, et al. Trends Endocrinol Metab. 2023 Sep;34(9):505-525. doi: 10.1016/j.tem.2023.06.006. Epub 2023 Jul 17. Trends Endocrinol Metab. 2023. PMID: 37468430 Free PMC article. Review.
Feasibility of Conducting Comparative Effectiveness Research and Validation of a Clinical Disease Activity Score for Chronic Nonbacterial Osteomyelitis.
Wu EY, Oliver M, Scheck J, Lapidus S, Akca UK, Yasin S, Stern SM, Insalaco A, Pardeo M, Simonini G, Marrani E, Wang X, Huang B, Kovalick LK, Rosenwasser N, Casselman G, Liau A, Shao Y, Yang C, Mosa DM, Tucker L, Girschick H, Laxer RM, Akikusa JD, Hedrich CM, Onel K, Dedeoglu F, Twilt M, Ferguson PJ, Ozen S, Zhao Y. Wu EY, et al. J Rheumatol. 2023 Oct;50(10):1333-1340. doi: 10.3899/jrheum.2022-1323. Epub 2023 Jul 1. J Rheumatol. 2023. PMID: 37399459 Free PMC article.
Machine learning for ECG diagnosis and risk stratification of occlusion myocardial infarction.
Al-Zaiti SS, Martin-Gill C, Zègre-Hemsey JK, Bouzid Z, Faramand Z, Alrawashdeh MO, Gregg RE, Helman S, Riek NT, Kraevsky-Phillips K, Clermont G, Akcakaya M, Sereika SM, Van Dam P, Smith SW, Birnbaum Y, Saba S, Sejdic E, Callaway CW. Al-Zaiti SS, et al. Nat Med. 2023 Jul;29(7):1804-1813. doi: 10.1038/s41591-023-02396-3. Epub 2023 Jun 29. Nat Med. 2023. PMID: 37386246 Free PMC article.
Supporting the 'lived expertise' of older adults with type 1 diabetes: An applied focus group analysis to characterize barriers, facilitators, and strategies for self-management in a growing and understudied population.
Cristello Sarteau A, Muthukkumar R, Smith C, Busby-Whitehead J, Lich KH, Pratley RE, Thambuluru S, Weinstein J, Weinstock RS, Young LA, Kahkoska AR. Cristello Sarteau A, et al. Diabet Med. 2024 Jan;41(1):e15156. doi: 10.1111/dme.15156. Epub 2023 Jun 22. Diabet Med. 2024. PMID: 37278610
Canonical correlation analysis for multi-omics: Application to cross-cohort analysis.
Jiang MZ, Aguet F, Ardlie K, Chen J, Cornell E, Cruz D, Durda P, Gabriel SB, Gerszten RE, Guo X, Johnson CW, Kasela S, Lange LA, Lappalainen T, Liu Y, Reiner AP, Smith J, Sofer T, Taylor KD, Tracy RP, VanDenBerg DJ, Wilson JG, Rich SS, Rotter JI, Love MI, Raffield LM, Li Y; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Analysis Working Group. Jiang MZ, et al. PLoS Genet. 2023 May 22;19(5):e1010517. doi: 10.1371/journal.pgen.1010517. eCollection 2023 May. PLoS Genet. 2023. PMID: 37216410 Free PMC article.
Sinonasal quality of life in primary ciliary dyskinesia.
Stack T, Norris M, Kim S, Lamb M, Zeatoun A, Mohammad I, Worden C, Thorp BD, Klatt-Cromwell C, Ebert CS Jr, Senior BA, Kimple AJ. Stack T, et al. Int Forum Allergy Rhinol. 2023 Nov;13(11):2101-2104. doi: 10.1002/alr.23180. Epub 2023 May 25. Int Forum Allergy Rhinol. 2023. PMID: 37203268 Free PMC article.
Precision medicine in type 2 diabetes: A systematic review of treatment effect heterogeneity for GLP1-receptor agonists and SGLT2-inhibitors.
Young KG, McInnes EH, Massey RJ, Kahkohska AR, Pilla SJ, Raghaven S, Stanislawski MA, Tobias DK, McGovern AP, Dawed AY, Jones AG, Pearson ER, Dennis JM; ADA/EASD Precision Medicine in Diabetes Initiative Consortium. Young KG, et al. medRxiv [Preprint]. 2023 Apr 22:2023.04.21.23288868. doi: 10.1101/2023.04.21.23288868. medRxiv. 2023. Update in: Commun Med (Lond). 2023 Oct 5;3(1):131. doi: 10.1038/s43856-023-00359-w PMID: 37131814 Free PMC article. Updated. Preprint.
Investigating Gene-Diet Interactions Impacting the Association Between Macronutrient Intake and Glycemic Traits.
Westerman KE, Walker ME, Gaynor SM, Wessel J, DiCorpo D, Ma J, Alonso A, Aslibekyan S, Baldridge AS, Bertoni AG, Biggs ML, Brody JA, Chen YI, Dupuis J, Goodarzi MO, Guo X, Hasbani NR, Heath A, Hidalgo B, Irvin MR, Johnson WC, Kalyani RR, Lange L, Lemaitre RN, Liu CT, Liu S, Moon JY, Nassir R, Pankow JS, Pettinger M, Raffield LM, Rasmussen-Torvik LJ, Selvin E, Senn MK, Shadyab AH, Smith AV, Smith NL, Steffen L, Talegakwar S, Taylor KD, de Vries PS, Wilson JG, Wood AC, Yanek LR, Yao J, Zheng Y, Boerwinkle E, Morrison AC, Fornage M, Russell TP, Psaty BM, Levy D, Heard-Costa NL, Ramachandran VS, Mathias RA, Arnett DK, Kaplan R, North KE, Correa A, Carson A, Rotter JI, Rich SS, Manson JE, Reiner AP, Kooperberg C, Florez JC, Meigs JB, Merino J, Tobias DK, Chen H, Manning AK. Westerman KE, et al. Diabetes. 2023 May 1;72(5):653-665. doi: 10.2337/db22-0851. Diabetes. 2023. PMID: 36791419 Free PMC article.
Machine Learning for the ECG Diagnosis and Risk Stratification of Occlusion Myocardial Infarction at First Medical Contact.
Al-Zaiti S, Martin-Gill C, Zégre-Hemsey J, Bouzid Z, Faramand Z, Alrawashdeh M, Gregg R, Helman S, Riek N, Kraevsky-Phillips K, Clermont G, Akcakaya M, Sereika S, Van Dam P, Smith S, Birnbaum Y, Saba S, Sejdic E, Callaway C. Al-Zaiti S, et al. Res Sq [Preprint]. 2023 Jan 30:rs.3.rs-2510930. doi: 10.21203/rs.3.rs-2510930/v1. Res Sq. 2023. Update in: Nat Med. 2023 Jul;29(7):1804-1813. doi: 10.1038/s41591-023-02396-3 PMID: 36778371 Free PMC article. Updated. Preprint.
Social determinants of health and asthma.
Espaillat AE, Hernandez ML, Burbank AJ. Espaillat AE, et al. Curr Opin Allergy Clin Immunol. 2023 Apr 1;23(2):144-150. doi: 10.1097/ACI.0000000000000872. Epub 2022 Dec 27. Curr Opin Allergy Clin Immunol. 2023. PMID: 36728768 Free PMC article. Review.
Estimation of a Machine Learning-Based Decision Rule to Reduce Hypoglycemia Among Older Adults With Type 1 Diabetes: A Post Hoc Analysis of Continuous Glucose Monitoring in the WISDM Study.
Kahkoska AR, Shah KS, Kosorok MR, Miller KM, Rickels M, Weinstock RS, Young LA, Pratley RE. Kahkoska AR, et al. J Diabetes Sci Technol. 2024 Sep;18(5):1079-1086. doi: 10.1177/19322968221149040. Epub 2023 Jan 11. J Diabetes Sci Technol. 2024. PMID: 36629330 Free PMC article. Clinical Trial.
Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies.
Li X, Quick C, Zhou H, Gaynor SM, Liu Y, Chen H, Selvaraj MS, Sun R, Dey R, Arnett DK, Bielak LF, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Correa A, Cupples LA, Curran JE, de Vries PS, Duggirala R, Freedman BI, Göring HHH, Guo X, Haessler J, Kalyani RR, Kooperberg C, Kral BG, Lange LA, Manichaikul A, Martin LW, McGarvey ST, Mitchell BD, Montasser ME, Morrison AC, Naseri T, O'Connell JR, Palmer ND, Peyser PA, Psaty BM, Raffield LM, Redline S, Reiner AP, Reupena MS, Rice KM, Rich SS, Sitlani CM, Smith JA, Taylor KD, Vasan RS, Willer CJ, Wilson JG, Yanek LR, Zhao W; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Lipids Working Group; Rotter JI, Natarajan P, Peloso GM, Li Z, Lin X. Li X, et al. Nat Genet. 2023 Jan;55(1):154-164. doi: 10.1038/s41588-022-01225-6. Epub 2022 Dec 23. Nat Genet. 2023. PMID: 36564505 Free PMC article.
The next step: Replacing step 1 as a metric for residency application.
Berk GA, Ho TD, Stack-Pyle TJ, Zeatoun A, Kong KA, Chaskes MB, Thorp BD, Ebert CS Jr, DeMason CE, Kimple AJ, Senior BA. Berk GA, et al. Laryngoscope Investig Otolaryngol. 2022 Oct 20;7(6):1756-1761. doi: 10.1002/lio2.947. eCollection 2022 Dec. Laryngoscope Investig Otolaryngol. 2022. PMID: 36544915 Free PMC article.
Editorial: The complement system in autoimmunity.
Wu EY, Alexander JJ, Fukui S. Wu EY, et al. Front Immunol. 2022 Nov 16;13:1085525. doi: 10.3389/fimmu.2022.1085525. eCollection 2022. Front Immunol. 2022. PMID: 36466859 Free PMC article. No abstract available.
Whole-exome sequencing study identifies four novel gene loci associated with diabetic kidney disease.
Pan Y, Sun X, Mi X, Huang Z, Hsu Y, Hixson JE, Munzy D, Metcalf G, Franceschini N, Tin A, Köttgen A, Francis M; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium TOPMed Kidney Function Working Group; Brody JA, Kestenbaum B, Sitlani CM, Mychaleckyj JC, Kramer H, Lange LA, Guo X, Hwang SJ, Irvin MR, Smith JA, Yanek LR, Vaidya D, Chen YI, Fornage M, Lloyd-Jones DM, Hou L, Mathias RA, Mitchell BD, Peyser PA, Kardia SLR, Arnett DK, Correa A, Raffield LM, Vasan RS, Cupple LA, Levy D, Kaplan RC, North KE, Rotter JI, Kooperberg C, Reiner AP, Psaty BM, Tracy RP, Gibbs RA, Morrison AC, Feldman H, Boerwinkle E, He J, Kelly TN; CRIC Study Investigators. Pan Y, et al. Hum Mol Genet. 2023 Mar 6;32(6):1048-1060. doi: 10.1093/hmg/ddac290. Hum Mol Genet. 2023. PMID: 36444934 Free PMC article.
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.
Li Z, Li X, Zhou H, Gaynor SM, Selvaraj MS, Arapoglou T, Quick C, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Auer PL, Bielak LF, Bis JC, Blackwell TW, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Conomos MP, Correa A, Cupples LA, Curran JE, de Vries PS, Duggirala R, Franceschini N, Freedman BI, Göring HHH, Guo X, Kalyani RR, Kooperberg C, Kral BG, Lange LA, Lin BM, Manichaikul A, Manning AK, Martin LW, Mathias RA, Meigs JB, Mitchell BD, Montasser ME, Morrison AC, Naseri T, O'Connell JR, Palmer ND, Peyser PA, Psaty BM, Raffield LM, Redline S, Reiner AP, Reupena MS, Rice KM, Rich SS, Smith JA, Taylor KD, Taub MA, Vasan RS, Weeks DE, Wilson JG, Yanek LR, Zhao W; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Lipids Working Group; Rotter JI, Willer CJ, Natarajan P, Peloso GM, Lin X. Li Z, et al. Nat Methods. 2022 Dec;19(12):1599-1611. doi: 10.1038/s41592-022-01640-x. Epub 2022 Oct 27. Nat Methods. 2022. PMID: 36303018 Free PMC article.
MagicalRsq: Machine-learning-based genotype imputation quality calibration.
Sun Q, Yang Y, Rosen JD, Jiang MZ, Chen J, Liu W, Wen J, Raffield LM, Pace RG, Zhou YH, Wright FA, Blackman SM, Bamshad MJ, Gibson RL, Cutting GR, Knowles MR, Schrider DR, Fuchsberger C, Li Y. Sun Q, et al. Am J Hum Genet. 2022 Nov 3;109(11):1986-1997. doi: 10.1016/j.ajhg.2022.09.009. Epub 2022 Oct 4. Am J Hum Genet. 2022. PMID: 36198314 Free PMC article.
Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations.
Elgart M, Lyons G, Romero-Brufau S, Kurniansyah N, Brody JA, Guo X, Lin HJ, Raffield L, Gao Y, Chen H, de Vries P, Lloyd-Jones DM, Lange LA, Peloso GM, Fornage M, Rotter JI, Rich SS, Morrison AC, Psaty BM, Levy D, Redline S; NHLBI’s Trans-Omics in Precision Medicine (TOPMed) Consortium; Sofer T. Elgart M, et al. Commun Biol. 2022 Aug 22;5(1):856. doi: 10.1038/s42003-022-03812-z. Commun Biol. 2022. PMID: 35995843 Free PMC article.
A Data-Driven Approach in an Unbiased Sample Reveals Equivalent Sex Ratio of Autism Spectrum Disorder-Associated Impairment in Early Childhood.
Burrows CA, Grzadzinski RL, Donovan K, Stallworthy IC, Rutsohn J, St John T, Marrus N, Parish-Morris J, MacIntyre L, Hampton J, Pandey J, Shen MD, Botteron KN, Estes AM, Dager SR, Hazlett HC, Pruett JR Jr, Schultz RT, Zwaigenbaum L, Truong KN, Piven J, Elison JT; IBIS Network. Burrows CA, et al. Biol Psychiatry. 2022 Oct 15;92(8):654-662. doi: 10.1016/j.biopsych.2022.05.027. Epub 2022 Jun 7. Biol Psychiatry. 2022. PMID: 35965107 Free PMC article.
Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program.
DiCorpo D, Gaynor SM, Russell EM, Westerman KE, Raffield LM, Majarian TD, Wu P, Sarnowski C, Highland HM, Jackson A, Hasbani NR, de Vries PS, Brody JA, Hidalgo B, Guo X, Perry JA, O'Connell JR, Lent S, Montasser ME, Cade BE, Jain D, Wang H, D'Oliveira Albanus R, Varshney A, Yanek LR, Lange L, Palmer ND, Almeida M, Peralta JM, Aslibekyan S, Baldridge AS, Bertoni AG, Bielak LF, Chen CS, Chen YI, Choi WJ, Goodarzi MO, Floyd JS, Irvin MR, Kalyani RR, Kelly TN, Lee S, Liu CT, Loesch D, Manson JE, Minster RL, Naseri T, Pankow JS, Rasmussen-Torvik LJ, Reiner AP, Reupena MS, Selvin E, Smith JA, Weeks DE, Xu H, Yao J, Zhao W, Parker S, Alonso A, Arnett DK, Blangero J, Boerwinkle E, Correa A, Cupples LA, Curran JE, Duggirala R, He J, Heckbert SR, Kardia SLR, Kim RW, Kooperberg C, Liu S, Mathias RA, McGarvey ST, Mitchell BD, Morrison AC, Peyser PA, Psaty BM, Redline S, Shuldiner AR, Taylor KD, Vasan RS, Viaud-Martinez KA, Florez JC, Wilson JG, Sladek R, Rich SS, Rotter JI, Lin X, Dupuis J, Meigs JB, Wessel J, Manning AK. DiCorpo D, et al. Commun Biol. 2022 Jul 28;5(1):756. doi: 10.1038/s42003-022-03702-4. Commun Biol. 2022. PMID: 35902682 Free PMC article.
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies.
Gorski M, Rasheed H, Teumer A, Thomas LF, Graham SE, Sveinbjornsson G, Winkler TW, Günther F, Stark KJ, Chai JF, Tayo BO, Wuttke M, Li Y, Tin A, Ahluwalia TS, Ärnlöv J, Åsvold BO, Bakker SJL, Banas B, Bansal N, Biggs ML, Biino G, Böhnke M, Boerwinkle E, Bottinger EP, Brenner H, Brumpton B, Carroll RJ, Chaker L, Chalmers J, Chee ML, Chee ML, Cheng CY, Chu AY, Ciullo M, Cocca M, Cook JP, Coresh J, Cusi D, de Borst MH, Degenhardt F, Eckardt KU, Endlich K, Evans MK, Feitosa MF, Franke A, Freitag-Wolf S, Fuchsberger C, Gampawar P, Gansevoort RT, Ghanbari M, Ghasemi S, Giedraitis V, Gieger C, Gudbjartsson DF, Hallan S, Hamet P, Hishida A, Ho K, Hofer E, Holleczek B, Holm H, Hoppmann A, Horn K, Hutri-Kähönen N, Hveem K, Hwang SJ, Ikram MA, Josyula NS, Jung B, Kähönen M, Karabegović I, Khor CC, Koenig W, Kramer H, Krämer BK, Kühnel B, Kuusisto J, Laakso M, Lange LA, Lehtimäki T, Li M, Lieb W; Lifelines Cohort Study; Lind L, Lindgren CM, Loos RJF, Lukas MA, Lyytikäinen LP, Mahajan A, Matias-Garcia PR, Meisinger C, Meitinger T, Melander O, Milaneschi Y, Mishra PP, Mononen N, Morris AP, Mychaleckyj JC, Nadkarni GN, Naito M, Nakatochi M, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Nutile T,… See abstract for full author list ➔ Gorski M, et al. Kidney Int. 2022 Sep;102(3):624-639. doi: 10.1016/j.kint.2022.05.021. Epub 2022 Jun 16. Kidney Int. 2022. PMID: 35716955 Free PMC article.
Burn Pit Exposure Is Associated With Increased Sinonasal Disease.
Hill CJ, Meyer CD, McLean JE, Anderson DC, Hao Y, Lin FC, Kimple AJ, Capra GG. Hill CJ, et al. J Occup Environ Med. 2022 Aug 1;64(8):629-634. doi: 10.1097/JOM.0000000000002551. Epub 2022 Jun 9. J Occup Environ Med. 2022. PMID: 35673272 Free PMC article.
Immunological Interaction of HLA-DPB1 and Proteinase 3 in ANCA Vasculitis is Associated with Clinical Disease Activity.
Chen DP, McInnis EA, Wu EY, Stember KG, Hogan SL, Hu Y, Henderson CD, Blazek LN, Mallal S, Karosiene E, Peters B, Sidney J, James EA, Kwok WW, Jennette JC, Ciavatta DJ, Falk RJ, Free ME. Chen DP, et al. J Am Soc Nephrol. 2022 Aug;33(8):1517-1527. doi: 10.1681/ASN.2021081142. Epub 2022 Jun 7. J Am Soc Nephrol. 2022. PMID: 35672132 Free PMC article.
TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data.
Huang L, Rosen JD, Sun Q, Chen J, Wheeler MM, Zhou Y, Min YI, Kooperberg C, Conomos MP, Stilp AM, Rich SS, Rotter JI, Manichaikul A, Loos RJF, Kenny EE, Blackwell TW, Smith AV, Jun G, Sedlazeck FJ, Metcalf G, Boerwinkle E; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Raffield LM, Reiner AP, Auer PL, Li Y. Huang L, et al. Am J Hum Genet. 2022 Jun 2;109(6):1175-1181. doi: 10.1016/j.ajhg.2022.04.006. Epub 2022 May 2. Am J Hum Genet. 2022. PMID: 35504290 Free PMC article.
Interferon activated gene 204 protects against bone loss in experimental periodontitis.
Swanson KV, Girnary M, Alves T, Ting JP, Divaris K, Beck J, Pucinelli CM, da Silva RAB, Uyan D, Wilson JE, Seaman WT, Webster-Cyriaque J, Vias N, Jiao Y, Cantley L, Marlier A, Arnold RR, Marchesan JT. Swanson KV, et al. J Periodontol. 2022 Sep;93(9):1366-1377. doi: 10.1002/JPER.21-0668. Epub 2022 Jun 10. J Periodontol. 2022. PMID: 35404474 Free PMC article.
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.
Nakao T, Bick AG, Taub MA, Zekavat SM, Uddin MM, Niroula A, Carty CL, Lane J, Honigberg MC, Weinstock JS, Pampana A, Gibson CJ, Griffin GK, Clarke SL, Bhattacharya R, Assimes TL, Emery LS, Stilp AM, Wong Q, Broome J, Laurie CA, Khan AT, Smith AV, Blackwell TW, Codd V, Nelson CP, Yoneda ZT, Peralta JM, Bowden DW, Irvin MR, Boorgula M, Zhao W, Yanek LR, Wiggins KL, Hixson JE, Gu CC, Peloso GM, Roden DM, Reupena MS, Hwu CM, DeMeo DL, North KE, Kelly S, Musani SK, Bis JC, Lloyd-Jones DM, Johnsen JM, Preuss M, Tracy RP, Peyser PA, Qiao D, Desai P, Curran JE, Freedman BI, Tiwari HK, Chavan S, Smith JA, Smith NL, Kelly TN, Hidalgo B, Cupples LA, Weeks DE, Hawley NL, Minster RL; Samoan Obesity, Lifestyle and Genetic Adaptations Study (OLaGA) Group; Deka R, Naseri TT, de las Fuentes L, Raffield LM, Morrison AC, Vries PS, Ballantyne CM, Kenny EE, Rich SS, Whitsel EA, Cho MH, Shoemaker MB, Pace BS, Blangero J, Palmer ND, Mitchell BD, Shuldiner AR, Barnes KC, Redline S, Kardia SLR, Abecasis GR, Becker LC, Heckbert SR, He J, Post W, Arnett DK, Vasan RS, Darbar D, Weiss ST, McGarvey ST, de Andrade M, Chen YI, Kaplan RC, Meyers DA, Custer BS, Correa A, Psaty BM, Fornage M, Manson JE, Boerwinkle … See abstract for full author list ➔ Nakao T, et al. Sci Adv. 2022 Apr 8;8(14):eabl6579. doi: 10.1126/sciadv.abl6579. Epub 2022 Apr 6. Sci Adv. 2022. PMID: 35385311 Free PMC article.
Genetic Examination of Hematological Parameters in SARS-CoV-2 Infection and COVID-19.
Rowland B, Sun Q, Wang W, Miller-Fleming T, Cox N, Graff M, Faucon A, Shuey MM, Blue EE, Auer P, Li Y, Sankaran VG, Reiner AP, Raffield LM. Rowland B, et al. medRxiv [Preprint]. 2022 Feb 28:2022.02.28.22271562. doi: 10.1101/2022.02.28.22271562. medRxiv. 2022. Update in: Blood Cells Mol Dis. 2023 Nov;103:102782. doi: 10.1016/j.bcmd.2023.102782 PMID: 35262092 Free PMC article. Updated. Preprint.
Rare coding variants in RCN3 are associated with blood pressure.
He KY, Kelly TN, Wang H, Liang J, Zhu L, Cade BE, Assimes TL, Becker LC, Beitelshees AL, Bielak LF, Bress AP, Brody JA, Chang YC, Chang YC, de Vries PS, Duggirala R, Fox ER, Franceschini N, Furniss AL, Gao Y, Guo X, Haessler J, Hung YJ, Hwang SJ, Irvin MR, Kalyani RR, Liu CT, Liu C, Martin LW, Montasser ME, Muntner PM, Mwasongwe S, Naseri T, Palmas W, Reupena MS, Rice KM, Sheu WH, Shimbo D, Smith JA, Snively BM, Yanek LR, Zhao W, Blangero J, Boerwinkle E, Chen YI, Correa A, Cupples LA, Curran JE, Fornage M, He J, Hou L, Kaplan RC, Kardia SLR, Kenny EE, Kooperberg C, Lloyd-Jones D, Loos RJF, Mathias RA, McGarvey ST, Mitchell BD, North KE, Peyser PA, Psaty BM, Raffield LM, Rao DC, Redline S, Reiner AP, Rich SS, Rotter JI, Taylor KD, Tracy R, Vasan RS; Samoan Obesity, Lifestyle and Genetic Adaptations Study (OLaGA) Group, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Morrison AC, Levy D, Chakravarti A, Arnett DK, Zhu X. He KY, et al. BMC Genomics. 2022 Feb 19;23(1):148. doi: 10.1186/s12864-022-08356-4. BMC Genomics. 2022. PMID: 35183128 Free PMC article.
Pharmacokinetic-based failure of a detergent virucidal for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) nasal infections: A preclinical study and randomized controlled trial.
Esther CR Jr, Kimura KS, Mikami Y, Edwards CE, Das SR, Freeman MH, Strickland BA, Brown HM, Wessinger BC, Gupta VC, Von Wahlde K, Sheng Q, Huang LC, Bacon DR, Kimple AJ, Ceppe AS, Kato T, Pickles RJ, Randell SH, Baric RS, Turner JH, Boucher RC. Esther CR Jr, et al. Int Forum Allergy Rhinol. 2022 Sep;12(9):1137-1147. doi: 10.1002/alr.22975. Epub 2022 Jan 31. Int Forum Allergy Rhinol. 2022. PMID: 35040594 Free PMC article. Clinical Trial.
Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.
Downie CG, Dimos SF, Bien SA, Hu Y, Darst BF, Polfus LM, Wang Y, Wojcik GL, Tao R, Raffield LM, Armstrong ND, Polikowsky HG, Below JE, Correa A, Irvin MR, Rasmussen-Torvik LJF, Carlson CS, Phillips LS, Liu S, Pankow JS, Rich SS, Rotter JI, Buyske S, Matise TC, North KE, Avery CL, Haiman CA, Loos RJF, Kooperberg C, Graff M, Highland HM. Downie CG, et al. Diabetologia. 2022 Mar;65(3):477-489. doi: 10.1007/s00125-021-05635-9. Epub 2021 Dec 24. Diabetologia. 2022. PMID: 34951656 Free PMC article.
Obesity Duration, Severity, and Distribution Trajectories and Cardiovascular Disease Risk in the Atherosclerosis Risk in Communities Study.
Raffield LM, Howard AG, Graff M, Lin DY, Cheng S, Demerath E, Ndumele C, Palta P, Rebholz CM, Seidelmann S, Yu B, Gordon-Larsen P, North KE, Avery CL. Raffield LM, et al. J Am Heart Assoc. 2021 Dec 21;10(24):e019946. doi: 10.1161/JAHA.121.019946. Epub 2021 Dec 10. J Am Heart Assoc. 2021. PMID: 34889111 Free PMC article.
Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol.
Wu P, Moon JY, Daghlas I, Franco G, Porneala BC, Ahmadizar F, Richardson TG, Isaksen JL, Hindy G, Yao J, Sitlani CM, Raffield LM, Yanek LR, Feitosa MF, Cuadrat RRC, Qi Q, Arfan Ikram M, Ellervik C, Ericson U, Goodarzi MO, Brody JA, Lange L, Mercader JM, Vaidya D, An P, Schulze MB, Masana L, Ghanbari M, Olesen MS, Cai J, Guo X, Floyd JS, Jäger S, Province MA, Kalyani RR, Psaty BM, Orho-Melander M, Ridker PM, Kanters JK, Uitterlinden A, Davey Smith G, Gill D, Kaplan RC, Kavousi M, Raghavan S, Chasman DI, Rotter JI, Meigs JB, Florez JC, Dupuis J, Liu CT, Merino J. Wu P, et al. Diabetes Care. 2022 Jan 1;45(1):232-240. doi: 10.2337/dc21-1284. Diabetes Care. 2022. PMID: 34789503 Free PMC article.
A large-scale transcriptome-wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine-mapping.
Tapia AL, Rowland BT, Rosen JD, Preuss M, Young K, Graff M, Choquet H, Couper DJ, Buyske S, Bien SA, Jorgenson E, Kooperberg C, Loos RJF, Morrison AC, North KE, Yu B, Reiner AP, Li Y, Raffield LM. Tapia AL, et al. Genet Epidemiol. 2022 Feb;46(1):3-16. doi: 10.1002/gepi.22436. Epub 2021 Nov 15. Genet Epidemiol. 2022. PMID: 34779012 Free PMC article.
Clonal Hematopoiesis Is Associated With Higher Risk of Stroke.
Bhattacharya R, Zekavat SM, Haessler J, Fornage M, Raffield L, Uddin MM, Bick AG, Niroula A, Yu B, Gibson C, Griffin G, Morrison AC, Psaty BM, Longstreth WT, Bis JC, Rich SS, Rotter JI, Tracy RP, Correa A, Seshadri S, Johnson A, Collins JM, Hayden KM, Madsen TE, Ballantyne CM, Jaiswal S, Ebert BL, Kooperberg C, Manson JE, Whitsel EA; NHLBI Trans-Omics for Precision Medicine Program; Natarajan P, Reiner AP. Bhattacharya R, et al. Stroke. 2022 Mar;53(3):788-797. doi: 10.1161/STROKEAHA.121.037388. Epub 2021 Nov 8. Stroke. 2022. PMID: 34743536 Free PMC article.
Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults.
Olson NC, Raffield LM, Moxley AH, Miller-Fleming TW, Auer PL, Franceschini N, Ngo D, Thornton TA, Lange EM, Li Y, Nickerson DA, Zakai NA, Gerszten RE, Cox NJ, Correa A, Mohlke KL, Reiner AP. Olson NC, et al. Circ Genom Precis Med. 2021 Dec;14(6):e003421. doi: 10.1161/CIRCGEN.121.003421. Epub 2021 Oct 28. Circ Genom Precis Med. 2021. PMID: 34706549 Free PMC article.
Recent Advances in Pediatric Vasculitis.
Cannon L, Wu EY. Cannon L, et al. Rheum Dis Clin North Am. 2021 Nov;47(4):781-796. doi: 10.1016/j.rdc.2021.07.007. Epub 2021 Aug 27. Rheum Dis Clin North Am. 2021. PMID: 34635304 Free PMC article. Review.
Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.
Mikhaylova AV, McHugh CP, Polfus LM, Raffield LM, Boorgula MP, Blackwell TW, Brody JA, Broome J, Chami N, Chen MH, Conomos MP, Cox C, Curran JE, Daya M, Ekunwe L, Glahn DC, Heard-Costa N, Highland HM, Hobbs BD, Ilboudo Y, Jain D, Lange LA, Miller-Fleming TW, Min N, Moon JY, Preuss MH, Rosen J, Ryan K, Smith AV, Sun Q, Surendran P, de Vries PS, Walter K, Wang Z, Wheeler M, Yanek LR, Zhong X, Abecasis GR, Almasy L, Barnes KC, Beaty TH, Becker LC, Blangero J, Boerwinkle E, Butterworth AS, Chavan S, Cho MH, Choquet H, Correa A, Cox N, DeMeo DL, Faraday N, Fornage M, Gerszten RE, Hou L, Johnson AD, Jorgenson E, Kaplan R, Kooperberg C, Kundu K, Laurie CA, Lettre G, Lewis JP, Li B, Li Y, Lloyd-Jones DM, Loos RJF, Manichaikul A, Meyers DA, Mitchell BD, Morrison AC, Ngo D, Nickerson DA, Nongmaithem S, North KE, O'Connell JR, Ortega VE, Pankratz N, Perry JA, Psaty BM, Rich SS, Soranzo N, Rotter JI, Silverman EK, Smith NL, Tang H, Tracy RP, Thornton TA, Vasan RS, Zein J, Mathias RA; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Reiner AP, Auer PL. Mikhaylova AV, et al. Am J Hum Genet. 2021 Oct 7;108(10):1836-1851. doi: 10.1016/j.ajhg.2021.08.007. Epub 2021 Sep 27. Am J Hum Genet. 2021. PMID: 34582791 Free PMC article.
Prehospital ECG with ST-depression and T-wave inversion are associated with new onset heart failure in individuals transported by ambulance for suspected acute coronary syndrome.
Zègre-Hemsey JK, Hogg M, Crandell J, Pelter MM, Gettes L, Chung EH, Pearson D, Tochiki P, Studnek JR, Rosamond W. Zègre-Hemsey JK, et al. J Electrocardiol. 2021 Nov-Dec;69S:23-28. doi: 10.1016/j.jelectrocard.2021.08.005. Epub 2021 Aug 13. J Electrocardiol. 2021. PMID: 34456036 Free PMC article.
Analyses of biomarker traits in diverse UK biobank participants identify associations missed by European-centric analysis strategies.
Sun Q, Graff M, Rowland B, Wen J, Huang L, Miller-Fleming TW, Haessler J, Preuss MH, Chai JF, Lee MP, Avery CL, Cheng CY, Franceschini N, Sim X, Cox NJ, Kooperberg C, North KE, Li Y, Raffield LM. Sun Q, et al. J Hum Genet. 2022 Feb;67(2):87-93. doi: 10.1038/s10038-021-00968-0. Epub 2021 Aug 11. J Hum Genet. 2022. PMID: 34376796 Free PMC article.
Strategies for Reimagining Complex Care.
Sandhu S, deJong NA, Ming DY. Sandhu S, et al. J Gen Intern Med. 2021 Sep;36(9):2856-2857. doi: 10.1007/s11606-021-06956-6. Epub 2021 Jun 25. J Gen Intern Med. 2021. PMID: 34173201 Free PMC article. No abstract available.
Multilevel growth curve analyses of behavioral activation for anhedonia (BATA) and mindfulness-based cognitive therapy effects on anhedonia and resting-state functional connectivity: Interim results of a randomized trial✰.
Cernasov P, Walsh EC, Kinard JL, Kelley L, Phillips R, Pisoni A, Eisenlohr-Moul TA, Arnold M, Lowery SC, Ammirato M, Truong K, Nagy GA, Oliver JA, Haworth K, Smoski M, Dichter GS. Cernasov P, et al. J Affect Disord. 2021 Sep 1;292:161-171. doi: 10.1016/j.jad.2021.05.054. Epub 2021 May 28. J Affect Disord. 2021. PMID: 34126308 Free PMC article. Clinical Trial.
DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function.
Matías-García PR, Ward-Caviness CK, Raffield LM, Gao X, Zhang Y, Wilson R, Gào X, Nano J, Bostom A, Colicino E, Correa A, Coull B, Eaton C, Hou L, Just AC, Kunze S, Lange L, Lange E, Lin X, Liu S, Nwanaji-Enwerem JC, Reiner A, Shen J, Schöttker B, Vokonas P, Zheng Y, Young B, Schwartz J, Horvath S, Lu A, Whitsel EA, Koenig W, Adamski J, Winkelmann J, Brenner H, Baccarelli AA, Gieger C, Peters A, Franceschini N, Waldenberger M. Matías-García PR, et al. Clin Epigenetics. 2021 Jun 2;13(1):121. doi: 10.1186/s13148-021-01082-w. Clin Epigenetics. 2021. PMID: 34078457 Free PMC article.
Pharmacokinetic-based failure of a detergent virucidal for SARS-COV-2 nasal infections.
Esther CR Jr, Kimura KS, Mikami Y, Edwards CE, Das SR, Freeman MH, Strickland BA, Brown HM, Wessinger BC, Gupta VC, Von Wahlde K, Sheng Q, Huang LC, Bacon DR, Kimple AJ, Ceppe AS, Kato T, Pickles RJ, Randell SH, Baric RS, Turner JH, Boucher RC. Esther CR Jr, et al. Res Sq [Preprint]. 2021 May 14:rs.3.rs-500168. doi: 10.21203/rs.3.rs-500168/v1. Res Sq. 2021. Update in: Int Forum Allergy Rhinol. 2022 Sep;12(9):1137-1147. doi: 10.1002/alr.22975 PMID: 34013253 Free PMC article. Updated. Preprint.
Soluble CD14 Levels in the Jackson Heart Study: Associations With Cardiovascular Disease Risk and Genetic Variants.
Stanislawski MA, Lange LA, Raffield LM, Zakai NA, Meyer M, Ferrier K, Szeto MD, Leavitt C, Shortt JA, Thornton TA, Tracy RP, Auer PL, Reiner AP, Lange EM, Olson NC. Stanislawski MA, et al. Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):e369-e378. doi: 10.1161/ATVBAHA.121.316035. Epub 2021 Apr 29. Arterioscler Thromb Vasc Biol. 2021. PMID: 33910371 Free PMC article.
Development and Validation of Machine Learning-Based Race-Specific Models to Predict 10-Year Risk of Heart Failure: A Multicohort Analysis.
Segar MW, Jaeger BC, Patel KV, Nambi V, Ndumele CE, Correa A, Butler J, Chandra A, Ayers C, Rao S, Lewis AA, Raffield LM, Rodriguez CJ, Michos ED, Ballantyne CM, Hall ME, Mentz RJ, de Lemos JA, Pandey A. Segar MW, et al. Circulation. 2021 Jun 15;143(24):2370-2383. doi: 10.1161/CIRCULATIONAHA.120.053134. Epub 2021 Apr 13. Circulation. 2021. PMID: 33845593 Free PMC article.
SARS-CoV-2 infection of the oral cavity and saliva.
Huang N, Pérez P, Kato T, Mikami Y, Okuda K, Gilmore RC, Conde CD, Gasmi B, Stein S, Beach M, Pelayo E, Maldonado JO, Lafont BA, Jang SI, Nasir N, Padilla RJ, Murrah VA, Maile R, Lovell W, Wallet SM, Bowman NM, Meinig SL, Wolfgang MC, Choudhury SN, Novotny M, Aevermann BD, Scheuermann RH, Cannon G, Anderson CW, Lee RE, Marchesan JT, Bush M, Freire M, Kimple AJ, Herr DL, Rabin J, Grazioli A, Das S, French BN, Pranzatelli T, Chiorini JA, Kleiner DE, Pittaluga S, Hewitt SM, Burbelo PD, Chertow D; NIH COVID-19 Autopsy Consortium; HCA Oral and Craniofacial Biological Network; Frank K, Lee J, Boucher RC, Teichmann SA, Warner BM, Byrd KM. Huang N, et al. Nat Med. 2021 May;27(5):892-903. doi: 10.1038/s41591-021-01296-8. Epub 2021 Mar 25. Nat Med. 2021. PMID: 33767405 Free PMC article.
Eculizumab exposure in children and young adults: indications, practice patterns, and outcomes-a Pediatric Nephrology Research Consortium study.
Muff-Luett M, Sanderson KR, Engen RM, Zahr RS, Wenderfer SE, Tran CL, Sharma S, Cai Y, Ingraham S, Winnicki E, Weaver DJ, Hunley TE, Kiessling SG, Seamon M, Woroniecki R, Miyashita Y, Xiao N, Omoloja AA, Kizilbash SJ, Mansuri A, Kallash M, Yu Y, Sherman AK, Srivastava T, Nester CM. Muff-Luett M, et al. Pediatr Nephrol. 2021 Aug;36(8):2349-2360. doi: 10.1007/s00467-021-04965-5. Epub 2021 Mar 10. Pediatr Nephrol. 2021. PMID: 33693990 Free PMC article.
The Joint Impact of COVID-19 Vaccination and Non-Pharmaceutical Interventions on Infections, Hospitalizations, and Mortality: An Agent-Based Simulation.
Patel MD, Rosenstrom E, Ivy JS, Mayorga ME, Keskinocak P, Boyce RM, Hassmiller Lich K, Smith RL, Johnson KT, Swann JL. Patel MD, et al. medRxiv [Preprint]. 2021 Jan 10:2020.12.30.20248888. doi: 10.1101/2020.12.30.20248888. medRxiv. 2021. Update in: JAMA Netw Open. 2021 Jun 1;4(6):e2110782. doi: 10.1001/jamanetworkopen.2021.10782 PMID: 33442712 Free PMC article. Updated. Preprint.
Effect of Sickle Cell Trait and APOL1 Genotype on the Association of Soluble uPAR with Kidney Function Measures in Black Americans.
Reiner AP, Raffield LM, Franceschini N, Auer PL, Lange EM, Nickerson DA, Zakai NA, Correa A, Olson N; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Consortium; Natinal Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Consortium. Reiner AP, et al. Clin J Am Soc Nephrol. 2021 Feb 8;16(2):287-289. doi: 10.2215/CJN.12100720. Epub 2020 Dec 2. Clin J Am Soc Nephrol. 2021. PMID: 33268503 Free PMC article. No abstract available.
Stimulator of interferon genes (STING) is an essential proviral host factor for human rhinovirus species A and C.
McKnight KL, Swanson KV, Austgen K, Richards C, Mitchell JK, McGivern DR, Fritch E, Johnson J, Remlinger K, Magid-Slav M, Kapustina M, You S, Lemon SM. McKnight KL, et al. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27598-27607. doi: 10.1073/pnas.2014940117. Epub 2020 Oct 15. Proc Natl Acad Sci U S A. 2020. PMID: 33060297 Free PMC article.
Diabetic vasculopathy: macro and microvascular injury.
Mota RI, Morgan SE, Bahnson EM. Mota RI, et al. Curr Pathobiol Rep. 2020 Mar;8(1):1-14. doi: 10.1007/s40139-020-00205-x. Epub 2020 Jan 27. Curr Pathobiol Rep. 2020. PMID: 32655983 Free PMC article.
Numerical evaluation of spray position for improved nasal drug delivery.
Basu S, Holbrook LT, Kudlaty K, Fasanmade O, Wu J, Burke A, Langworthy BW, Farzal Z, Mamdani M, Bennett WD, Fine JP, Senior BA, Zanation AM, Ebert CS Jr, Kimple AJ, Thorp BD, Frank-Ito DO, Garcia GJM, Kimbell JS. Basu S, et al. Sci Rep. 2020 Jun 29;10(1):10568. doi: 10.1038/s41598-020-66716-0. Sci Rep. 2020. PMID: 32601278 Free PMC article.
Sinus Development and Pneumatization in a Primary Ciliary Dyskinesia Cohort.
Pappa AK, Sullivan KM, Lopez EM, Adams KN, Zanation AM, Ebert CS Jr, Thorp BD, Senior BA, Leigh MW, Knowles MR, Kimple AJ. Pappa AK, et al. Am J Rhinol Allergy. 2021 Jan;35(1):72-76. doi: 10.1177/1945892420933175. Epub 2020 Jun 19. Am J Rhinol Allergy. 2021. PMID: 32551925 Free PMC article.
SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.
Hou YJ, Okuda K, Edwards CE, Martinez DR, Asakura T, Dinnon KH 3rd, Kato T, Lee RE, Yount BL, Mascenik TM, Chen G, Olivier KN, Ghio A, Tse LV, Leist SR, Gralinski LE, Schäfer A, Dang H, Gilmore R, Nakano S, Sun L, Fulcher ML, Livraghi-Butrico A, Nicely NI, Cameron M, Cameron C, Kelvin DJ, de Silva A, Margolis DM, Markmann A, Bartelt L, Zumwalt R, Martinez FJ, Salvatore SP, Borczuk A, Tata PR, Sontake V, Kimple A, Jaspers I, O'Neal WK, Randell SH, Boucher RC, Baric RS. Hou YJ, et al. Cell. 2020 Jul 23;182(2):429-446.e14. doi: 10.1016/j.cell.2020.05.042. Epub 2020 May 27. Cell. 2020. PMID: 32526206 Free PMC article.