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Page 1
Smaller Pancreas Volume in Insulin-Dependent Monogenic Diabetes.
Williams JM, Hilmes MA, Letourneau-Freiberg LR, Kandasamy B, Braun D, Greeley SAW, Philipson L, Powers AC, Virostko J, Moore DJ, Wright JJ. Williams JM, et al. Diabetes. 2025 May 22:db250318. doi: 10.2337/db25-0318. Online ahead of print. Diabetes. 2025. PMID: 40402101
HLA DQA1*05 and Risk of Antitumor Necrosis Factor Treatment Failure and Anti-Drug Antibody Development in Children With Crohn's Disease.
Adler J, Galanko JA, Ammoury R, Benkov KJ, Bousvaros A, Boyle B, Cabrera JM, Chun KY, Dorsey J, Ebach DR, Firestine AM, Gulati AS, Herfarth HH, Jester TW, Kaplan JL, Leibowitz I, Linville TM, Margolis PA, Minar P, Molle-Rios Z, Moses J, Olano K, Pashankar DS, Pitch L, Saeed SA, Samson CM, Sandberg K, Steiner SJ, Strople JA, Sullivan JS, Wali PD, Kappelman MD. Adler J, et al. Am J Gastroenterol. 2025 May 1;120(5):1076-1086. doi: 10.14309/ajg.0000000000003135. Epub 2024 Oct 18. Am J Gastroenterol. 2025. PMID: 40315028 Clinical Trial.
Statin Use Is Associated With Protection Against Acute Cholangitis in Patients With Primary Sclerosing Cholangitis: A Multicenter Retrospective Cohort Study.
Kulkarni C, Cholankeril G, Fardeen T, Rathkey J, Khan S, Murag S, Lerrigo R, Kamal A, Mannalithara A, Jalal P, Ahmed A, Vierling J, Goel A, Sinha SR. Kulkarni C, et al. Clin Transl Gastroenterol. 2025 Apr 1;16(4):e00816. doi: 10.14309/ctg.0000000000000816. Clin Transl Gastroenterol. 2025. PMID: 40272937 Free PMC article.
Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes.
Tutino M, Yu NY, Hatzikotoulas K, Park YC, Kreitmaier P, Katsoula G, Berner R, Casteels K, Elding Larsson H, Kordonouri O, Ołtarzewski M, Szypowska A, Ott R, Weiss A, Winkler C, Zapardiel-Gonzalo J, Petrera A, Hauck SM, Bonifacio E, Ziegler AG, Zeggini E. Tutino M, et al. Nat Commun. 2025 Apr 22;16(1):3750. doi: 10.1038/s41467-025-58972-3. Nat Commun. 2025. PMID: 40263317 Free PMC article.
GPR35 prevents osmotic stress induced cell damage.
Elias JE, Debela M, Sewell GW, Stopforth RJ, Partl H, Heissbauer S, Holland LM, Karlsen TH, Kaser A, Kaneider NC. Elias JE, et al. Commun Biol. 2025 Mar 22;8(1):478. doi: 10.1038/s42003-025-07848-9. Commun Biol. 2025. PMID: 40121360 Free PMC article.
The efficacy of islet autoantibody screening with or without genetic pre-screening strategies for the identification of presymptomatic type 1 diabetes.
Bonifacio E, Coelho R, Ewald DA, Gemulla G, Hubmann M, Jarosz-Chobot P, Kohls M, Kordonouri O, Lampasona V, Narendran P, Pociot F, Šumník Z, Szypowska A, Zapardiel-Gonzalo J, Ziegler AG. Bonifacio E, et al. Diabetologia. 2025 Jun;68(6):1101-1107. doi: 10.1007/s00125-025-06408-4. Epub 2025 Mar 19. Diabetologia. 2025. PMID: 40105972 Free PMC article. Review.
Enterovirus VP1 protein and HLA class I hyperexpression in pancreatic islet cells of organ donors with type 1 diabetes.
Rodriguez-Calvo T, Laiho JE, Oikarinen M, Akhbari P, Flaxman C, Worthington T, Apaolaza P, Kaddis JS, Kusmartseva I, Tauriainen S, Campbell-Thompson M, Atkinson MA, von Herrath M, Hyöty H, Morgan NG, Pugliese A, Richardson SJ; nPOD-Virus group. Rodriguez-Calvo T, et al. Diabetologia. 2025 Jun;68(6):1197-1210. doi: 10.1007/s00125-025-06384-9. Epub 2025 Mar 17. Diabetologia. 2025. PMID: 40090995 Free PMC article.
Joint analysis of the nPOD-Virus Group data: the association of enterovirus with type 1 diabetes is supported by multiple markers of infection in pancreas tissue.
Richardson SJ, Rodriguez-Calvo T, Laiho JE, Kaddis JS, Nyalwidhe JO, Kusmartseva I, Morfopoulou S, Petrosino JF, Plagnol V, Maedler K, Morris MA, Nadler JL, Atkinson MA, von Herrath M, Lloyd RE, Hyoty H, Morgan NG, Pugliese A; nPOD-Virus Group. Richardson SJ, et al. Diabetologia. 2025 Jun;68(6):1226-1241. doi: 10.1007/s00125-025-06401-x. Epub 2025 Mar 17. Diabetologia. 2025. PMID: 40090994 Free PMC article.
Marked improvement in HbA1c following introduction of biosimilar insulin to treatment regimen of children and youth with type 1 diabetes in Mali: A randomised controlled trial.
Besançon S, Haynes A, Togo AD, Sandy JL, Maniam J, Sidibe AT, Djéneba S, de Beaufort C, Perolini MC, Gastaldi G, Beran D, Eigenmann C, Ogle GD. Besançon S, et al. Diabet Med. 2025 May;42(5):e70007. doi: 10.1111/dme.70007. Epub 2025 Mar 3. Diabet Med. 2025. PMID: 40033680 Clinical Trial.
Circulating and Magnetic Resonance Imaging Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease.
Dillman JR, Tkach JA, Fletcher JG, Bruining DH, Lu A, Kugathasan S, Alazraki AL, Knight-Scott J, Stidham RW, Adler J, Minar P, Trapnell BC, Bonkowski EL, Jurrell H, Lopez-Nunez O, Collins MH, Swanson SD, Fei L, Qian L, Towbin AJ, Kocaoglu M, Anton CG, Imbus RA, Dudley JA, Denson LA. Dillman JR, et al. Inflamm Bowel Dis. 2025 May 12;31(5):1380-1391. doi: 10.1093/ibd/izae319. Inflamm Bowel Dis. 2025. PMID: 39853252
Interferon-α promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic β-cells.
Carré A, Samassa F, Zhou Z, Perez-Hernandez J, Lekka C, Manganaro A, Oshima M, Liao H, Parker R, Nicastri A, Brandao B, Colli ML, Eizirik DL, Aluri J, Patel D, Göransson M, Burgos Morales O, Anderson A, Landry L, Kobaisi F, Scharfmann R, Marselli L, Marchetti P, You S, Nakayama M, Hadrup SR, Kent SC, Richardson SJ, Ternette N, Mallone R. Carré A, et al. Nat Commun. 2025 Jan 17;16(1):765. doi: 10.1038/s41467-025-55908-9. Nat Commun. 2025. PMID: 39824805 Free PMC article.
Project ECHO Diabetes Trial Improves Outcomes for Medically Underserved People.
Walker AF, Haller MJ, Addala A, Filipp SL, Lal RA, Gurka MJ, Figg LE, Hechavarria M, Zaharieva DP, Malden KG, Hood KK, Westen SC, Wong JJ, Donahoo WT, Basina M, Bernier AV, Maahs DM; ECHO Diabetes Study Team. Walker AF, et al. Diabetes Care. 2025 Feb 1;48(2):243-250. doi: 10.2337/dc24-2100. Diabetes Care. 2025. PMID: 39688288 Free PMC article. Clinical Trial.
Protocol for a feasibility and acceptability study for UK general population paediatric type 1 diabetes screening-the EarLy Surveillance for Autoimmune diabetes (ELSA) study.
Quinn LM, Dias RP, Greenfield SM, Richter AG, Garstang J, Shukla D, Acharjee A, Gkoutos G, Oram R, Faustini S, Boiko O, Litchfield I, Boardman F, Zakia F, Burt C, Connop C, Lepley A, Gardner C, Dayan C, Barrett T, Narendran P. Quinn LM, et al. Diabet Med. 2025 May;42(5):e15490. doi: 10.1111/dme.15490. Epub 2024 Dec 2. Diabet Med. 2025. PMID: 39623620 Free PMC article.
Human ITGAV variants are associated with immune dysregulation, brain abnormalities, and colitis.
Ghasempour S, Warner N, Guan R, Rodari MM, Ivanochko D, Whittaker Hawkins R, Marwaha A, Nowak JK, Liang Y, Mulder DJ, Stallard L, Li M, Yu DD, Pluthero FG, Batura V, Zhao M, Siddiqui I, Upton JEM, Hulst JM, Kahr WHA, Mendoza-Londono R, Charbit-Henrion F, Hoefsloot LH, Khiat A, Moreira D, Trindade E, Espinheira MDC, Pinto Pais I, Weerts MJA, Douben H, Kotlarz D, Snapper SB, Klein C, Dowling JJ, Julien JP, Joosten M, Cerf-Bensussan N, Freeman SA, Parlato M, van Ham TJ, Muise AM. Ghasempour S, et al. J Exp Med. 2024 Dec 2;221(12):e20240546. doi: 10.1084/jem.20240546. Epub 2024 Nov 11. J Exp Med. 2024. PMID: 39526957 Free PMC article.
The Type 1 Diabetes T Cell Receptor and B Cell Receptor Repository in the AIRR Data Commons: a practical guide for access, use and contributions through the Type 1 Diabetes AIRR Consortium.
Hanna SJ, Bonami RH, Corrie B, Westley M, Posgai AL, Luning Prak ET, Breden F, Michels AW, Brusko TM; Type 1 Diabetes AIRR Consortium. Hanna SJ, et al. Diabetologia. 2025 Jan;68(1):186-202. doi: 10.1007/s00125-024-06298-y. Epub 2024 Oct 29. Diabetologia. 2025. PMID: 39467874 Free PMC article.
A Proteomics Pipeline for Generating Clinical Grade Biomarker Candidates from Data-Independent Acquisition Mass Spectrometry (DIA-MS) Discovery.
Fu Q, Vegesna M, Sundararaman N, Damoc E, Arrey TN, Pashkova A, Mengesha E, Debbas P, Joung S, Li D, Cheng S, Braun J, McGovern DPB, Murray CI, Xuan Y, Van Eyk JE. Fu Q, et al. Angew Chem Int Ed Engl. 2024 Dec 20;63(52):e202409446. doi: 10.1002/anie.202409446. Epub 2024 Nov 11. Angew Chem Int Ed Engl. 2024. PMID: 39432331
HLA DQA1*05 and risk of anti-TNF treatment failure and anti-drug antibody development in children with Crohn's Disease: HLA DQA1*05 and Pediatric Crohn's Disease.
Adler J, Galanko JA, Ammoury R, Benkov KJ, Bousvaros A, Boyle B, Cabrera JM, Chun KY, Dorsey J, Ebach DR, Firestine AM, Gulati AS, Herfarth HH, Jester TW, Kaplan JL, Leibowitz I, Linville TM, Margolis PA, Minar P, Molle-Rios Z, Moses J, Olano K, Pashankar DS, Pitch L, Saeed SA, Samson CM, Sandberg K, Steiner SJ, Strople JA, Sullivan JS, Wali PD, Kappelman MD. Adler J, et al. Am J Gastroenterol. 2024 Oct 18. doi: 10.14309/ajg.0000000000003135. Online ahead of print. Am J Gastroenterol. 2024. PMID: 39423015
Durable Immune Response and Long-term Efficacy of COVID-19 Vaccination in Children With Inflammatory Bowel Disease.
Kastl AJ, Brenner EJ, Weaver KN, Zhang X, Strople JA, Adler J, Dubinsky MC, Bousvaros A, Watkins R, Dai X, Chen W, Cross RK, Higgins PDR, Ungaro RC, Bewtra M, Bellaguarda EA, Farraye FA, Chun KY, Zikry M, Bastidas M, Firestine AM, Craig RG, Boccieri ME, Long MD, Kappelman MD. Kastl AJ, et al. Inflamm Bowel Dis. 2024 Oct 16:izae225. doi: 10.1093/ibd/izae225. Online ahead of print. Inflamm Bowel Dis. 2024. PMID: 39412147
Calcitonin gene-related peptide promotes epithelial reparative and anticolitic functions of IL-4 educated human macrophages.
Callejas BE, Sousa JA, Flannigan KL, Wang A, Higgins E, Herik AI, Li S, Rajeev S, Rosentreter R, Panaccione R, McKay DM. Callejas BE, et al. Am J Physiol Gastrointest Liver Physiol. 2025 Jan 1;328(1):G1-G16. doi: 10.1152/ajpgi.00159.2024. Epub 2024 Oct 8. Am J Physiol Gastrointest Liver Physiol. 2025. PMID: 39378308 Free article.
Noninvasive, microbiome-based diagnosis of inflammatory bowel disease.
Zheng J, Sun Q, Zhang M, Liu C, Su Q, Zhang L, Xu Z, Lu W, Ching J, Tang W, Cheung CP, Hamilton AL, Wilson O'Brien AL, Wei SC, Bernstein CN, Rubin DT, Chang EB, Morrison M, Kamm MA, Chan FKL, Zhang J, Ng SC. Zheng J, et al. Nat Med. 2024 Dec;30(12):3555-3567. doi: 10.1038/s41591-024-03280-4. Epub 2024 Oct 4. Nat Med. 2024. PMID: 39367251 Free PMC article.
The Circulating Methylome in Childhood-Onset Inflammatory Bowel Disease.
Noble A, Adams A, Nowak J, Cheng G, Nayak K, Quinn A, Kristiansen M, Kalla R, Ventham NT, Giachero F, Jayamanne C, Hansen R, Hold GL, El-Omar E, Croft NM, Wilson D, Beattie RM, Ashton JJ, Zilbauer M, Ennis S, Uhlig HH, Satsangi J. Noble A, et al. J Crohns Colitis. 2025 Mar 5;19(3):jjae157. doi: 10.1093/ecco-jcc/jjae157. J Crohns Colitis. 2025. PMID: 39365013 Free PMC article.
Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetes.
Hill TG, Gao R, Benrick A, Kothegala L, Rorsman N, Santos C, Acreman S, Briant LJ, Dou H, Gandasi NR, Guida C, Haythorne E, Wallace M, Knudsen JG, Miranda C, Tolö J, Clark A, Davison L, Størling J, Tarasov A, Ashcroft FM, Rorsman P, Zhang Q. Hill TG, et al. Nat Metab. 2024 Nov;6(11):2070-2081. doi: 10.1038/s42255-024-01139-z. Epub 2024 Sep 23. Nat Metab. 2024. PMID: 39313541 Free PMC article.
Post-operative Crohn's Disease Recurrence and Infectious Complications: A Transcriptomic Analysis.
Chen KA, Gartner V, Darlington KC, Silverstein SR, Kennedy Ng MM, Butler L, Avalos K, Nishiyama NC, Joisa CU, Schaner MR, Lian G, Beasley C, Lau GW, Bauer MJ, Zhu LC, Kapadia MR, Gomez SM, Furey TS, Sheikh SZ. Chen KA, et al. Dig Dis Sci. 2025 Jan;70(1):203-214. doi: 10.1007/s10620-024-08595-3. Epub 2024 Aug 31. Dig Dis Sci. 2025. PMID: 39215865 Free PMC article.
Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn's disease.
Li J, Simmons AJ, Hawkins CV, Chiron S, Ramirez-Solano MA, Tasneem N, Kaur H, Xu Y, Revetta F, Vega PN, Bao S, Cui C, Tyree RN, Raber LW, Conner AN, Pilat JM, Jacobse J, McNamara KM, Allaman MM, Raffa GA, Gobert AP, Asim M, Goettel JA, Choksi YA, Beaulieu DB, Dalal RL, Horst SN, Pabla BS, Huo Y, Landman BA, Roland JT, Scoville EA, Schwartz DA, Washington MK, Shyr Y, Wilson KT, Coburn LA, Lau KS, Liu Q. Li J, et al. Nat Commun. 2024 Aug 22;15(1):7204. doi: 10.1038/s41467-024-51580-7. Nat Commun. 2024. PMID: 39169060 Free PMC article.
Performance of bowel preparation quality scales in patients with Crohn's disease.
Solitano V, Siegel CA, Korzenik JR, Maratt JK, Rex DK, Maguire B, Bressler B, Grossmann J, Sedano R, McDonald JWD, Remillard J, Shackelton LM, Zou G, Feagan BG, Ma C, Jairath V. Solitano V, et al. Aliment Pharmacol Ther. 2024 Oct;60(8):1042-1050. doi: 10.1111/apt.18210. Epub 2024 Aug 11. Aliment Pharmacol Ther. 2024. PMID: 39129393
Discordant Effects of Janus Kinase Inhibition Ex Vivo on Inflammatory Responses in Colonic Compared to Ileal Mucosa.
Kaboub K, Abu-Taha H, Arrouasse J, Shaham-Barda E, Wasserberg N, Hayman-Manzur L, Friedenberg A, Levy-Barda A, Goren I, Levi Z, Banai-Eran H, Avni-Biron I, Ollech JE, Sharar-Fischler T, Yanai H, Cohen-Kedar S, Dotan I, Rabinowitz KM. Kaboub K, et al. J Crohns Colitis. 2025 Jan 11;19(1):jjae117. doi: 10.1093/ecco-jcc/jjae117. J Crohns Colitis. 2025. PMID: 39073573
Empowering emerging adults with type 1 diabetes: crafting a financial and health insurance toolkit through community-based participatory action research.
Blanchette JE, Lewis CB, Shannon CS, Kanchibhatla A, Rieke J, Roche MJ, Johnson DA, Williams D, Webb S, Diaz CN, Lundgrin EL, Allen NA, Litchman ML, Hatipoglu B. Blanchette JE, et al. Res Involv Engagem. 2024 Jul 23;10(1):75. doi: 10.1186/s40900-024-00602-1. Res Involv Engagem. 2024. PMID: 39044303 Free PMC article.
Involving different stakeholders in prioritising outcomes to assess healthcare systems response for type 1 diabetes management: Using co-creation approaches in Peru.
Zafra-Tanaka JH, Almeida G, Andrade Montalvo JE, Anza-Ramirez C, Jauregui J, Perez-Leon S, Lazo-Porras M, Mayo-Puchoc N, Taype-Rondán A, Miranda JJ, Beran D. Zafra-Tanaka JH, et al. Int J Health Plann Manage. 2024 Nov;39(6):1675-1695. doi: 10.1002/hpm.3821. Epub 2024 Jul 18. Int J Health Plann Manage. 2024. PMID: 39030852
Multi-omics analysis reveals drivers of loss of β-cell function after newly diagnosed autoimmune type 1 diabetes: An INNODIA multicenter study.
Armenteros JJA, Brorsson C, Johansen CH, Banasik K, Mazzoni G, Moulder R, Hirvonen K, Suomi T, Rasool O, Bruggraber SFA, Marcovecchio ML, Hendricks E, Al-Sari N, Mattila I, Legido-Quigley C, Suvitaival T, Chmura PJ, Knip M, Schulte AM, Lee JH, Sebastiani G, Grieco GE, Elo LL, Kaur S, Pociot F, Dotta F, Tree T, Lahesmaa R, Overbergh L, Mathieu C, Peakman M, Brunak S; INNODIA investigators. Armenteros JJA, et al. Diabetes Metab Res Rev. 2024 Jul;40(5):e3833. doi: 10.1002/dmrr.3833. Diabetes Metab Res Rev. 2024. PMID: 38961656
Effect of 48 Months of Closed-Loop Insulin Delivery on Residual C-Peptide Secretion and Glycemic Control in Newly Diagnosed Youth With Type 1 Diabetes: A Randomized Trial.
Ware J, Boughton CK, Allen JM, Wilinska ME, Hartnell S, Thankamony A, Randell T, Ghatak A, Besser REJ, Elleri D, Trevelyan N, Campbell FM, Sibayan J, Bailey R, Calhoun P, Dunseath G, Hovorka R; CLOuD Consortium. Ware J, et al. Diabetes Care. 2024 Aug 1;47(8):1441-1448. doi: 10.2337/dc24-0360. Diabetes Care. 2024. PMID: 38924772 Free PMC article. Clinical Trial.
Infection episodes and islet autoantibodies in children at increased risk for type 1 diabetes before and during the COVID-19 pandemic.
Zeller I, Weiss A, Arnolds S, Schütte-Borkovec K, Arabi S, von dem Berge T, Casteels K, Hommel A, Kordonouri O, Larsson HE, Lundgren M, Rochtus A, Snape MD, Szypowka A, Vatish M, Winkler C, Bonifacio E, Ziegler AG; GPPAD Study Group. Zeller I, et al. Infection. 2024 Dec;52(6):2465-2473. doi: 10.1007/s15010-024-02312-y. Epub 2024 Jun 14. Infection. 2024. PMID: 38874748 Free PMC article.
Implementation research: a protocol for two three-arm pragmatic randomised controlled trials on continuous glucose monitoring devices in people with type 1 diabetes in South Africa and Kenya.
Marbán-Castro E, Muhwava L, Kamau Y, Safary E, Rheeder P, Karsas M, Kemp T, Freitas J, Carrihill M, Dave J, Katambo D, Kimetto J, Allie R; Kenya ACCEDE study group; South Africa ACCEDE study group; Ndungu J, Sigwebela N, Akach D, Girdwood S, Erkosar B, Nichols BE, Haldane C, Vetter B, Shilton S. Marbán-Castro E, et al. Trials. 2024 May 21;25(1):331. doi: 10.1186/s13063-024-08132-7. Trials. 2024. PMID: 38773658 Free PMC article.
Associations of clinical, psychological, and sociodemographic characteristics and ecological momentary assessment completion in the 10-week Hypo-METRICS study: Hypoglycaemia MEasurements ThResholds and ImpaCtS.
Zaremba N, Martine-Edith G, Divilly P, Søholm U, Broadley M, Ali N, Abbink EJ, de Galan B, Cigler M, Mader JK, Brosen J, Pedersen-Bjergaard U, Vaag A, Evans M, Renard E, McCrimmon RJ, Heller S, Speight J, Pouwer F, Amiel SA, Choudhary P; Hypo‐RESOLVE Consortium. Zaremba N, et al. Diabet Med. 2024 Aug;41(8):e15345. doi: 10.1111/dme.15345. Epub 2024 May 17. Diabet Med. 2024. PMID: 38760977
MRI and Blood-based Biomarkers Are Associated With Surgery in Children and Adults With Ileal Crohn's Disease.
Dillman JR, Tkach JA, Fletcher JG, Bruining DH, Lu A, Kugathasan S, Alazraki AL, Knight-Scott J, Stidham RW, Adler J, Trapnell BC, Swanson SD, Fei L, Qian L, Towbin AJ, Kocaoglu M, Anton CG, Imbus RA, Dudley JA, Denson LA. Dillman JR, et al. Inflamm Bowel Dis. 2024 Nov 4;30(11):2181-2190. doi: 10.1093/ibd/izae101. Inflamm Bowel Dis. 2024. PMID: 38738296
Probiotics: are they beneficial?
Fehily SR, Basnayake C, Wright EK, Yao CK, Godsell J, Gibson PR, Kamm MA. Fehily SR, et al. Intern Med J. 2024 Jun;54(6):861-870. doi: 10.1111/imj.16388. Epub 2024 May 8. Intern Med J. 2024. PMID: 38717051 Review.
Genomic testing identifies monogenic causes in patients with very early-onset inflammatory bowel disease: a multicenter survey in an Iranian cohort.
Eslamian G, Jamee M, Momen T, Rohani P, Ebrahimi S, Mesdaghi M, Ghadimi S, Mansouri M, Mahdaviani SA, Sadeghi-Shabestari M, Fallahpour M, Shamsian BS, Eslami N, Sharafian S, Dara N, Nasri P, Amini N, Enayat J, Fallahi M, Ghasemi Hashtrodi L, Shojaei M, Guevara Becerra M, Uhlig HH, Chavoshzadeh Z. Eslamian G, et al. Clin Exp Immunol. 2024 Jun 20;217(1):1-11. doi: 10.1093/cei/uxae037. Clin Exp Immunol. 2024. PMID: 38651248 Free PMC article.
FixNCut: single-cell genomics through reversible tissue fixation and dissociation.
Jiménez-Gracia L, Marchese D, Nieto JC, Caratù G, Melón-Ardanaz E, Gudiño V, Roth S, Wise K, Ryan NK, Jensen KB, Hernando-Momblona X, Bernardes JP, Tran F, Sievers LK, Schreiber S, van den Berge M, Kole T, van der Velde PL, Nawijn MC, Rosenstiel P, Batlle E, Butler LM, Parish IA, Plummer J, Gut I, Salas A, Heyn H, Martelotto LG. Jiménez-Gracia L, et al. Genome Biol. 2024 Mar 29;25(1):81. doi: 10.1186/s13059-024-03219-5. Genome Biol. 2024. PMID: 38553769 Free PMC article.
A multi-ancestry genome-wide association study in type 1 diabetes.
Michalek DA, Tern C, Zhou W, Robertson CC, Farber E, Campolieto P, Chen WM, Onengut-Gumuscu S, Rich SS. Michalek DA, et al. Hum Mol Genet. 2024 May 18;33(11):958-968. doi: 10.1093/hmg/ddae024. Hum Mol Genet. 2024. PMID: 38453145 Free PMC article.
Demographic, Clinical, Management, and Outcome Characteristics of 8,004 Young Children With Type 1 Diabetes.
Sandy JL, Tittel SR, Rompicherla S, Karges B, James S, Rioles N, Zimmerman AG, Fröhlich-Reiterer E, Maahs DM, Lanzinger S, Craig ME, Ebekozien O; Australasian Diabetes Data Network (ADDN); T1D Exchanged Quality Improvement Collaborative (T1DX-QI); Prospective Diabetes Follow-Up Registry Initiative (DPV). Sandy JL, et al. Diabetes Care. 2024 Apr 1;47(4):660-667. doi: 10.2337/dc23-1317. Diabetes Care. 2024. PMID: 38305782
Forecasting the Incidence and Prevalence of Inflammatory Bowel Disease: A Canadian Nationwide Analysis.
Coward S, Benchimol EI, Bernstein CN, Avina-Zubieta A, Bitton A, Carroll MW, Cui Y, Hoentjen F, Hracs L, Jacobson K, Jones JL, King J, Kuenzig ME, Lu N, El-Matary W, Murthy SK, Nugent Z, Otley AR, Panaccione R, Peña-Sánchez JN, Singh H, Targownik LE, White D, Windsor JW, Kaplan GG; Canadian Gastro-Intestinal Epidemiology Consortium (CanGIEC). Coward S, et al. Am J Gastroenterol. 2024 Aug 1;119(8):1563-1570. doi: 10.14309/ajg.0000000000002687. Epub 2024 Feb 1. Am J Gastroenterol. 2024. PMID: 38299598 Free PMC article.
Serologic Response and Safety after a Third Dose of the COVID-19 BNT162b2 Vaccine in Patients with Inflammatory Bowel Diseases.
Edelman-Klapper H, Rabinowitz KM, Zittan E, Bar-Gil Shitrit A, Goren I, Avni-Biron I, Ollech JE, Lichtenstein L, Banai-Eran H, Yanai H, Snir Y, Pauker MH, Friedenberg A, Levy-Barda A, Broitman Y, Ben Zvi H, Perets TT, Eliakim R, Barkan R, Goren S, Cohen D, Dotan I; REsponses to COVid-19 vaccinE IsRaeli IBD group [RECOVERI]. Edelman-Klapper H, et al. Vaccines (Basel). 2023 Jul 20;11(7):1263. doi: 10.3390/vaccines11071263. Vaccines (Basel). 2023. PMID: 37515078 Free PMC article.
Unique features of the arterial blood-brain barrier.
Bell B, Anzi S, Sasson E, Ben-Zvi A. Bell B, et al. Fluids Barriers CNS. 2023 Jun 27;20(1):51. doi: 10.1186/s12987-023-00450-3. Fluids Barriers CNS. 2023. PMID: 37370096 Free PMC article.
A surge in serum mucosal cytokines associated with seroconversion in children at risk for type 1 diabetes.
Harrison LC, Bandala-Sanchez E, Oakey H, Colman PG, Watson K, Kim KW, Wu R, Hamilton-Williams EE, Stone NL, Haynes A, Thomson RL, Vuillermin PJ, Soldatos G, Rawlinson WD, McGorm KJ, Morahan G, Barry SC, Sinnott RO, Wentworth JM, Couper JJ, Penno MA; ENDIA Study Group. Harrison LC, et al. J Diabetes Investig. 2023 Sep;14(9):1092-1100. doi: 10.1111/jdi.14031. Epub 2023 Jun 13. J Diabetes Investig. 2023. PMID: 37312283 Free PMC article.
Residence in Peripheral Regions and Low Socioeconomic Status Are Associated With Worse Outcomes of Inflammatory Bowel Diseases: A Nationwide Study From the epi-IIRN.
Ledder O, Harel S, Lujan R, Friss C, Orlanski-Meyer E, Yogev D, Loewenberg Weisband Y, Greenfeld S, Kariv R, Lederman N, Matz E, Schwartz D, Focht G, Dotan I, Turner D. Ledder O, et al. Inflamm Bowel Dis. 2024 Jan 5;30(1):1-8. doi: 10.1093/ibd/izad034. Inflamm Bowel Dis. 2024. PMID: 36917191
Newly Diagnosed Crohn's Disease Patients in India and Israel Display Distinct Presentations and Serological Markers: Insights from Prospective Cohorts.
Goren I, Sharar Fischler T, Yanai H, Pal P, Adigopula B, Pendyala S, Ganesh G, Vishnubhotla R, Rabinowitz KM, Shaham Barda E, Yadamreddy D, Godny L, Peleg N, Banerjee R, Dotan I; Indo-Israeli IBD GastroEnterology Partnership (TIIIGER). Goren I, et al. J Clin Med. 2022 Nov 22;11(23):6899. doi: 10.3390/jcm11236899. J Clin Med. 2022. PMID: 36498474 Free PMC article.
Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped.
Tariq M, de Souza AH, Bensellam M, Chae H, Jaffredo M, Close AF, Deglasse JP, Santos LRB, Buemi A, Mourad NI, Wojtusciszyn A, Raoux M, Gilon P, Broca C, Jonas JC. Tariq M, et al. Diabetologia. 2023 Apr;66(4):709-723. doi: 10.1007/s00125-022-05842-y. Epub 2022 Dec 2. Diabetologia. 2023. PMID: 36459178
Unconstrained generation of synthetic antibody-antigen structures to guide machine learning methodology for antibody specificity prediction.
Robert PA, Akbar R, Frank R, Pavlović M, Widrich M, Snapkov I, Slabodkin A, Chernigovskaya M, Scheffer L, Smorodina E, Rawat P, Mehta BB, Vu MH, Mathisen IF, Prósz A, Abram K, Olar A, Miho E, Haug DTT, Lund-Johansen F, Hochreiter S, Haff IH, Klambauer G, Sandve GK, Greiff V. Robert PA, et al. Nat Comput Sci. 2022 Dec;2(12):845-865. doi: 10.1038/s43588-022-00372-4. Epub 2022 Dec 19. Nat Comput Sci. 2022. PMID: 38177393
SARS-CoV-2 IgG Antibody Levels in Women with IBD Vaccinated during Pregnancy.
Avni Biron I, Maayan Y, Mishael T, Hadar E, Neeman M, Plitman Mayo R, Sela HY, Yagel S, Goldenberg R, Ben Ya'acov A, Grisaru Granovsky S, Ollech JE, Edelman-Klapper H, Rabinowitz KM, Pauker MH, Yanai H, Goren S, Cohen D, Dotan I, Bar-Gil Shitrit A. Avni Biron I, et al. Vaccines (Basel). 2022 Oct 29;10(11):1833. doi: 10.3390/vaccines10111833. Vaccines (Basel). 2022. PMID: 36366342 Free PMC article.
Initial hospital length of stay and long-term survival of patients successfully resuscitated using extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest.
Alexy T, Kalra R, Kosmopoulos M, Bartos JA, Elliott A, Gutierrez Bernal A, Martin CM, John R, Shaffer AW, Raveendran G, Tsangaris A, Yannopoulos D. Alexy T, et al. Eur Heart J Acute Cardiovasc Care. 2023 Apr 3;12(3):175-183. doi: 10.1093/ehjacc/zuac141. Eur Heart J Acute Cardiovasc Care. 2023. PMID: 36346080
GIP Affects Hepatic Fat and Brown Adipose Tissue Thermogenesis but Not White Adipose Tissue Transcriptome in Type 1 Diabetes.
Heimbürger SMN, Hoe B, Nielsen CN, Bergman NC, Skov-Jeppesen K, Hartmann B, Holst JJ, Dela F, Overgaard J, Størling J, Vilsbøll T, Dejgaard TF, Havelund JF, Gorshkov V, Kjeldsen F, Færgeman NJ, Madsen MR, Christensen MB, Knop FK. Heimbürger SMN, et al. J Clin Endocrinol Metab. 2022 Nov 25;107(12):3261-3274. doi: 10.1210/clinem/dgac542. J Clin Endocrinol Metab. 2022. PMID: 36111559 Clinical Trial.
Closed-Loop Therapy and Preservation of C-Peptide Secretion in Type 1 Diabetes.
Boughton CK, Allen JM, Ware J, Wilinska ME, Hartnell S, Thankamony A, Randell T, Ghatak A, Besser REJ, Elleri D, Trevelyan N, Campbell FM, Sibayan J, Calhoun P, Bailey R, Dunseath G, Hovorka R; CLOuD Consortium. Boughton CK, et al. N Engl J Med. 2022 Sep 8;387(10):882-893. doi: 10.1056/NEJMoa2203496. N Engl J Med. 2022. PMID: 36069870 Clinical Trial.
Anti-TNFα Treatment Impairs Long-Term Immune Responses to COVID-19 mRNA Vaccine in Patients with Inflammatory Bowel Diseases.
Rabinowitz KM, Navon M, Edelman-Klapper H, Zittan E, Bar-Gil Shitrit A, Goren I, Avni-Biron I, Ollech JE, Lichtenstein L, Banai-Eran H, Yanai H, Snir Y, Pauker MH, Friedenberg A, Levy-Barda A, Segal A, Broitman Y, Maoz E, Ovadia B, Aharoni Golan M, Shachar E, Ben-Horin S, Maharshak N, Mor M, Ben Zvi H, Eliakim R, Barkan R, Sharar-Fischler T, Goren S, Krugliak N, Pichinuk E, Mor M, Werbner M, Alter J, Abu-Taha H, Kaboub K, Dessau M, Gal-Tanamy M, Cohen D, Freund NT, Dotan I, On Behalf Of The Responses To Covid-Vaccine Israeli Ibd. Rabinowitz KM, et al. Vaccines (Basel). 2022 Jul 26;10(8):1186. doi: 10.3390/vaccines10081186. Vaccines (Basel). 2022. PMID: 35893835 Free PMC article.
Multimodal intervention to improve the transition of patients with inflammatory bowel disease from pediatric to adult care: protocol for a randomized controlled trial.
Bollegala N, Barwick M, Fu N, Griffiths AM, Keefer L, Kohut SA, Kroeker KI, Lawrence S, Lee K, Mack DR, Walters TD, de Guzman J, Tersigni C, Miatello A, Benchimol EI. Bollegala N, et al. BMC Gastroenterol. 2022 May 18;22(1):251. doi: 10.1186/s12876-022-02307-9. BMC Gastroenterol. 2022. PMID: 35585484 Free PMC article.
The gut microbiota and gut disease.
Fehily SR, Basnayake C, Wright EK, Kamm MA. Fehily SR, et al. Intern Med J. 2021 Oct;51(10):1594-1604. doi: 10.1111/imj.15520. Intern Med J. 2021. PMID: 34664371 Review.
Defining Transabdominal Intestinal Ultrasound Treatment Response and Remission in Inflammatory Bowel Disease: Systematic Review and Expert Consensus Statement.
Ilvemark JFKF, Hansen T, Goodsall TM, Seidelin JB, Al-Farhan H, Allocca M, Begun J, Bryant RV, Carter D, Christensen B, Dubinsky MC, Gecse KB, Kucharzik T, Lu C, Maaser C, Maconi G, Nylund K, Palmela C, Wilson SR, Novak K, Wilkens R. Ilvemark JFKF, et al. J Crohns Colitis. 2022 May 10;16(4):554-580. doi: 10.1093/ecco-jcc/jjab173. J Crohns Colitis. 2022. PMID: 34614172 Free PMC article.
Evaluation of protocol amendments to the Environmental Determinants of Islet Autoimmunity (ENDIA) study during the COVID-19 pandemic.
Penno MAS, Anderson AJ, Thomson RL, McGorm K, Barry SC, Colman PG, Craig ME, Davis EA, Harris M, Haynes A, Morahan G, Oakey H, Rawlinson WD, Sinnott RO, Soldatos G, Vuillermin PJ, Wentworth JM, Harrison LC, Couper JJ; ENDIA Study Group. Penno MAS, et al. Diabet Med. 2021 Nov;38(11):e14638. doi: 10.1111/dme.14638. Epub 2021 Jul 19. Diabet Med. 2021. PMID: 34236734 Free PMC article. No abstract available.
Expanding the taxonomic range in the fecal metagenome.
Allnutt TR, Roth-Schulze AJ, Harrison LC. Allnutt TR, et al. BMC Bioinformatics. 2021 Jun 9;22(1):312. doi: 10.1186/s12859-021-04212-6. BMC Bioinformatics. 2021. PMID: 34107881 Free PMC article.
Modeling the Dynamics of T-Cell Development in the Thymus.
Robert PA, Kunze-Schumacher H, Greiff V, Krueger A. Robert PA, et al. Entropy (Basel). 2021 Apr 8;23(4):437. doi: 10.3390/e23040437. Entropy (Basel). 2021. PMID: 33918050 Free PMC article. Review.
Health-related quality of life in parents and partners of people with type 1 diabetes: Development and validation of type 1 diabetes and life (T1DAL) measures.
Hilliard ME, Minard CG, Marrero DG, de Wit M, DuBose SN, Verdejo A, Jaser SS, Kruger D, Monzavi R, Shah VN, Wadwa RP, Weinstock RS, Thompson D, Cao VT, Anderson BJ. Hilliard ME, et al. Fam Syst Health. 2021 Jun;39(2):234-247. doi: 10.1037/fsh0000507. Epub 2021 Apr 26. Fam Syst Health. 2021. PMID: 33900103 Free PMC article.
Diabetic ketoacidosis drives COVID-19 related hospitalizations in children with type 1 diabetes.
Alonso GT, Ebekozien O, Gallagher MP, Rompicherla S, Lyons SK, Choudhary A, Majidi S, Pinnaro CT, Balachandar S, Gangat M, Curda Roberts AJ, Marks BE, Creo A, Sanchez J, Seeherunvong T, Jimenez-Vega J, Patel NS, Wood JR, Gabriel L, Sumpter KM, Wilkes M, Rapaport R, Cymbaluk A, Wong JC, Sanda S, Albanese-O'neill A. Alonso GT, et al. J Diabetes. 2021 Aug;13(8):681-687. doi: 10.1111/1753-0407.13184. Epub 2021 Apr 27. J Diabetes. 2021. PMID: 33855813 Free PMC article.
Dose optimisation for Loss of Response to Vedolizumab- Pharmacokinetics and Immune Mechanisms.
Ungar B, Malickova K, Hanžel J, Abu Arisha M, Paul S, Rocha C, Ben Shatach Z, Abitbol CM, Haj Natour O, Selinger L, Yavzori M, Fudim E, Picard O, Shoval I, Eliakim R, Kopylov U, Magro F, Roblin X, Chowers Y, Drobne D, Lukas M, Ben Horin S. Ungar B, et al. J Crohns Colitis. 2021 Oct 7;15(10):1707-1719. doi: 10.1093/ecco-jcc/jjab067. J Crohns Colitis. 2021. PMID: 33837762
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