Lillehaug+JR - Search Results

1

SIX3 and SIX6 interact with GEMININ via C-terminal regions.

Turcu DC, Lillehaug JR, Seo HC. Turcu DC, et al. Biochem Biophys Rep. 2019 Oct 23;20:100695. doi: 10.1016/j.bbrep.2019.100695. eCollection 2019 Dec. Biochem Biophys Rep. 2019. PMID: 31844685 Free PMC article.

2

Two tales of Annexin A2 knock-down: One of compensatory effects by antisense RNA and another of a highly active hairpin ribozyme.

Aareskjold E, Grindheim AK, Hollås H, Goris M, Lillehaug JR, Vedeler A. Aareskjold E, et al. Biochem Pharmacol. 2019 Aug;166:253-263. doi: 10.1016/j.bcp.2019.05.028. Epub 2019 May 31. Biochem Pharmacol. 2019. PMID: 31158338 Free article.

3

CorA is a copper repressible surface-associated copper(I)-binding protein produced in Methylomicrobium album BG8.

Johnson KA, Ve T, Larsen O, Pedersen RB, Lillehaug JR, Jensen HB, Helland R, Karlsen OA. Johnson KA, et al. PLoS One. 2014 Feb 3;9(2):e87750. doi: 10.1371/journal.pone.0087750. eCollection 2014. PLoS One. 2014. PMID: 24498370 Free PMC article.

4

CXXC5 (retinoid-inducible nuclear factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia.

Astori A, Fredly H, Aloysius TA, Bullinger L, Mansat-De Mas V, de la Grange P, Delhommeau F, Hagen KM, Récher C, Dusanter-Fourt I, Knappskog S, Lillehaug JR, Pendino F, Bruserud Ø. Astori A, et al. Oncotarget. 2013 Sep;4(9):1438-48. doi: 10.18632/oncotarget.1195. Oncotarget. 2013. PMID: 23988457 Free PMC article.

5

Low BRAF and NRAS expression levels are associated with clinical benefit from DTIC therapy and prognosis in metastatic melanoma.

Birkeland E, Busch C, Berge EO, Geisler J, Jönsson G, Lillehaug JR, Knappskog S, Lønning PE. Birkeland E, et al. Clin Exp Metastasis. 2013 Oct;30(7):867-76. doi: 10.1007/s10585-013-9587-4. Epub 2013 May 15. Clin Exp Metastasis. 2013. PMID: 23673558 Free PMC article.

6

Functional characterisation of p53 mutants identified in breast cancers with suboptimal responses to anthracyclines or mitomycin.

Berge EO, Huun J, Lillehaug JR, Lønning PE, Knappskog S. Berge EO, et al. Biochim Biophys Acta. 2013 Mar;1830(3):2790-7. doi: 10.1016/j.bbagen.2012.12.004. Biochim Biophys Acta. 2013. PMID: 23246812

7

The Methylococcus capsulatus (Bath) secreted protein, MopE*, binds both reduced and oxidized copper.

Ve T, Mathisen K, Helland R, Karlsen OA, Fjellbirkeland A, Røhr ÅK, Andersson KK, Pedersen RB, Lillehaug JR, Jensen HB. Ve T, et al. PLoS One. 2012;7(8):e43146. doi: 10.1371/journal.pone.0043146. Epub 2012 Aug 20. PLoS One. 2012. PMID: 22916218 Free PMC article.

8

Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study.

Evjenth RH, Brenner AK, Thompson PR, Arnesen T, Frøystein NÅ, Lillehaug JR. Evjenth RH, et al. J Biol Chem. 2012 Mar 23;287(13):10081-10088. doi: 10.1074/jbc.M111.326587. Epub 2012 Feb 6. J Biol Chem. 2012. PMID: 22311970 Free PMC article.

9

Receptor for activated protein C kinase 1 (RACK1) is overexpressed in papillary thyroid carcinoma.

Myklebust LM, Akslen LA, Varhaug JE, Lillehaug JR. Myklebust LM, et al. Thyroid. 2011 Nov;21(11):1217-25. doi: 10.1089/thy.2010.0186. Epub 2011 Oct 18. Thyroid. 2011. PMID: 22007921

10

The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4.

Hole K, Van Damme P, Dalva M, Aksnes H, Glomnes N, Varhaug JE, Lillehaug JR, Gevaert K, Arnesen T. Hole K, et al. PLoS One. 2011;6(9):e24713. doi: 10.1371/journal.pone.0024713. Epub 2011 Sep 15. PLoS One. 2011. PMID: 21935442 Free PMC article.

11

Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency.

Rope AF, Wang K, Evjenth R, Xing J, Johnston JJ, Swensen JJ, Johnson WE, Moore B, Huff CD, Bird LM, Carey JC, Opitz JM, Stevens CA, Jiang T, Schank C, Fain HD, Robison R, Dalley B, Chin S, South ST, Pysher TJ, Jorde LB, Hakonarson H, Lillehaug JR, Biesecker LG, Yandell M, Arnesen T, Lyon GJ. Rope AF, et al. Am J Hum Genet. 2011 Jul 15;89(1):28-43. doi: 10.1016/j.ajhg.2011.05.017. Epub 2011 Jun 23. Am J Hum Genet. 2011. PMID: 21700266 Free PMC article.

12

Predictive and prognostic impact of TP53 mutations and MDM2 promoter genotype in primary breast cancer patients treated with epirubicin or paclitaxel.

Chrisanthar R, Knappskog S, Løkkevik E, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Skjønsberg G, Aas T, Schlichting E, Fjösne HE, Nysted A, Lillehaug JR, Lønning PE. Chrisanthar R, et al. PLoS One. 2011 Apr 27;6(4):e19249. doi: 10.1371/journal.pone.0019249. PLoS One. 2011. PMID: 21556366 Free PMC article. Clinical Trial.

13

Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase.

Van Damme P, Evjenth R, Foyn H, Demeyer K, De Bock PJ, Lillehaug JR, Vandekerckhove J, Arnesen T, Gevaert K. Van Damme P, et al. Mol Cell Proteomics. 2011 May;10(5):M110.004580. doi: 10.1074/mcp.M110.004580. Epub 2011 Mar 7. Mol Cell Proteomics. 2011. PMID: 21383206 Free PMC article.

14

Depletion of the human Nα-terminal acetyltransferase A induces p53-dependent apoptosis and p53-independent growth inhibition.

Gromyko D, Arnesen T, Ryningen A, Varhaug JE, Lillehaug JR. Gromyko D, et al. Int J Cancer. 2010 Dec 15;127(12):2777-89. doi: 10.1002/ijc.25275. Int J Cancer. 2010. PMID: 21351257

15

RINF (CXXC5) is overexpressed in solid tumors and is an unfavorable prognostic factor in breast cancer.

Knappskog S, Myklebust LM, Busch C, Aloysius T, Varhaug JE, Lønning PE, Lillehaug JR, Pendino F. Knappskog S, et al. Ann Oncol. 2011 Oct;22(10):2208-15. doi: 10.1093/annonc/mdq737. Epub 2011 Feb 16. Ann Oncol. 2011. PMID: 21325450 Free article.

16

The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians.

Knappskog S, Bjørnslett M, Myklebust LM, Huijts PE, Vreeswijk MP, Edvardsen H, Guo Y, Zhang X, Yang M, Ylisaukko-Oja SK, Alhopuro P, Arola J, Tollenaar RA, van Asperen CJ, Seynaeve C, Staalesen V, Chrisanthar R, Løkkevik E, Salvesen HB, Evans DG, Newman WG, Lin D, Aaltonen LA, Børresen-Dale AL, Tell GS, Stoltenberg C, Romundstad P, Hveem K, Lillehaug JR, Vatten L, Devilee P, Dørum A, Lønning PE. Knappskog S, et al. Cancer Cell. 2011 Feb 15;19(2):273-82. doi: 10.1016/j.ccr.2010.12.019. Cancer Cell. 2011. PMID: 21316605 Free article.

17

Alterations of the retinoblastoma gene in metastatic breast cancer.

Berge EO, Knappskog S, Lillehaug JR, Lønning PE. Berge EO, et al. Clin Exp Metastasis. 2011 Mar;28(3):319-26. doi: 10.1007/s10585-011-9375-y. Epub 2011 Jan 21. Clin Exp Metastasis. 2011. PMID: 21253829 Free PMC article.

18

Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers.

Berge EO, Knappskog S, Geisler S, Staalesen V, Pacal M, Børresen-Dale AL, Puntervoll P, Lillehaug JR, Lønning PE. Berge EO, et al. Mol Cancer. 2010 Jul 1;9:173. doi: 10.1186/1476-4598-9-173. Mol Cancer. 2010. PMID: 20594292 Free PMC article.

19

MGMT expression levels predict disease stabilisation, progression-free and overall survival in patients with advanced melanomas treated with DTIC.

Busch C, Geisler J, Lillehaug JR, Lønning PE. Busch C, et al. Eur J Cancer. 2010 Jul;46(11):2127-33. doi: 10.1016/j.ejca.2010.04.023. Epub 2010 Jun 10. Eur J Cancer. 2010. PMID: 20541396

20

Alterations in the p53 pathway and p16INK4a expression predict overall survival in metastatic melanoma patients treated with dacarbazine.

Busch C, Geisler J, Knappskog S, Lillehaug JR, Lønning PE. Busch C, et al. J Invest Dermatol. 2010 Oct;130(10):2514-6. doi: 10.1038/jid.2010.138. Epub 2010 May 27. J Invest Dermatol. 2010. PMID: 20505745 Free article. No abstract available.

21

Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcome.

Jönsson G, Busch C, Knappskog S, Geisler J, Miletic H, Ringnér M, Lillehaug JR, Borg A, Lønning PE. Jönsson G, et al. Clin Cancer Res. 2010 Jul 1;16(13):3356-67. doi: 10.1158/1078-0432.CCR-09-2509. Epub 2010 May 11. Clin Cancer Res. 2010. PMID: 20460471

22

Chk2 splice variants express a dominant-negative effect on the wild-type Chk2 kinase activity.

Berge EO, Staalesen V, Straume AH, Lillehaug JR, Lønning PE. Berge EO, et al. Biochim Biophys Acta. 2010 Mar;1803(3):386-95. doi: 10.1016/j.bbamcr.2010.01.005. Epub 2010 Jan 15. Biochim Biophys Acta. 2010. PMID: 20080130 Free article.

23

Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas.

Bruland O, Fluge Ø, Akslen LA, Eiken HG, Lillehaug JR, Varhaug JE, Knappskog PM. Bruland O, et al. BMC Cancer. 2009 Dec 8;9:425. doi: 10.1186/1471-2407-9-425. BMC Cancer. 2009. PMID: 19968886 Free PMC article.

24

Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity.

Evjenth R, Hole K, Karlsen OA, Ziegler M, Arnesen T, Lillehaug JR. Evjenth R, et al. J Biol Chem. 2009 Nov 6;284(45):31122-9. doi: 10.1074/jbc.M109.001347. Epub 2009 Sep 10. J Biol Chem. 2009. PMID: 19744929 Free PMC article.

25

Application of reverse-phase HPLC to quantify oligopeptide acetylation eliminates interference from unspecific acetyl CoA hydrolysis.

Evjenth R, Hole K, Ziegler M, Lillehaug JR. Evjenth R, et al. BMC Proc. 2009 Aug 4;3 Suppl 6(Suppl 6):S5. doi: 10.1186/1753-6561-3-S6-S5. BMC Proc. 2009. PMID: 19660098 Free PMC article.

26

A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1).

Arnesen T, Gromyko D, Kagabo D, Betts MJ, Starheim KK, Varhaug JE, Anderson D, Lillehaug JR. Arnesen T, et al. BMC Biochem. 2009 May 29;10:15. doi: 10.1186/1471-2091-10-15. BMC Biochem. 2009. PMID: 19480662 Free PMC article.

27

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans.

Arnesen T, Van Damme P, Polevoda B, Helsens K, Evjenth R, Colaert N, Varhaug JE, Vandekerckhove J, Lillehaug JR, Sherman F, Gevaert K. Arnesen T, et al. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8157-62. doi: 10.1073/pnas.0901931106. Epub 2009 May 6. Proc Natl Acad Sci U S A. 2009. PMID: 19420222 Free PMC article.

28

Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization.

Starheim KK, Gromyko D, Evjenth R, Ryningen A, Varhaug JE, Lillehaug JR, Arnesen T. Starheim KK, et al. Mol Cell Biol. 2009 Jul;29(13):3569-81. doi: 10.1128/MCB.01909-08. Epub 2009 Apr 27. Mol Cell Biol. 2009. PMID: 19398576 Free PMC article.

29

The protein Nalpha-terminal acetyltransferase hNaa10p (hArd1) is phosphorylated in HEK293 cells.

Målen H, Lillehaug JR, Arnesen T. Målen H, et al. BMC Res Notes. 2009 Mar 2;2:32. doi: 10.1186/1756-0500-2-32. BMC Res Notes. 2009. PMID: 19284711 Free PMC article.

30

Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis.

Pendino F, Nguyen E, Jonassen I, Dysvik B, Azouz A, Lanotte M, Ségal-Bendirdjian E, Lillehaug JR. Pendino F, et al. Blood. 2009 Apr 2;113(14):3172-81. doi: 10.1182/blood-2008-07-170035. Epub 2009 Jan 30. Blood. 2009. PMID: 19182210 Free article.

31

The protein acetyltransferase ARD1: a novel cancer drug target?

Arnesen T, Thompson PR, Varhaug JE, Lillehaug JR. Arnesen T, et al. Curr Cancer Drug Targets. 2008 Nov;8(7):545-53. doi: 10.2174/156800908786241113. Curr Cancer Drug Targets. 2008. PMID: 18991565 Review.

32

CHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancer.

Chrisanthar R, Knappskog S, Løkkevik E, Anker G, Østenstad B, Lundgren S, Berge EO, Risberg T, Mjaaland I, Maehle L, Engebretsen LF, Lillehaug JR, Lønning PE. Chrisanthar R, et al. PLoS One. 2008 Aug 26;3(8):e3062. doi: 10.1371/journal.pone.0003062. PLoS One. 2008. PMID: 18725978 Free PMC article.

33

The presence of multiple c-type cytochromes at the surface of the methanotrophic bacterium Methylococcus capsulatus (Bath) is regulated by copper.

Karlsen OA, Lillehaug JR, Jensen HB. Karlsen OA, et al. Mol Microbiol. 2008 Oct;70(1):15-26. doi: 10.1111/j.1365-2958.2008.06380.x. Epub 2008 Aug 4. Mol Microbiol. 2008. PMID: 18681943 Free article.

34

Identification of the human N(alpha)-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression.

Starheim KK, Arnesen T, Gromyko D, Ryningen A, Varhaug JE, Lillehaug JR. Starheim KK, et al. Biochem J. 2008 Oct 15;415(2):325-31. doi: 10.1042/BJ20080658. Biochem J. 2008. PMID: 18570629

35

An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE.

Helland R, Fjellbirkeland A, Karlsen OA, Ve T, Lillehaug JR, Jensen HB. Helland R, et al. J Biol Chem. 2008 May 16;283(20):13897-904. doi: 10.1074/jbc.M800340200. Epub 2008 Mar 18. J Biol Chem. 2008. PMID: 18348978 Free article.

36

LEDGF/p75 has increased expression in blasts from chemotherapy-resistant human acute myelogenic leukemia patients and protects leukemia cells from apoptosis in vitro.

Huang TS, Myklebust LM, Kjarland E, Gjertsen BT, Pendino F, Bruserud Ø, Døskeland SO, Lillehaug JR. Huang TS, et al. Mol Cancer. 2007 Apr 23;6:31. doi: 10.1186/1476-4598-6-31. Mol Cancer. 2007. PMID: 17451600 Free PMC article.

37

Mutations and polymorphisms of the p21B transcript in breast cancer.

Knappskog S, Chrisanthar R, Staalesen V, Børresen-Dale AL, Gram IT, Lillehaug JR, Lønning PE. Knappskog S, et al. Int J Cancer. 2007 Aug 15;121(4):908-10. doi: 10.1002/ijc.22777. Int J Cancer. 2007. PMID: 17443496

38

Breast cancer prognostication and prediction in the postgenomic era.

Lønning PE, Knappskog S, Staalesen V, Chrisanthar R, Lillehaug JR. Lønning PE, et al. Ann Oncol. 2007 Aug;18(8):1293-306. doi: 10.1093/annonc/mdm013. Epub 2007 Feb 21. Ann Oncol. 2007. PMID: 17317675 Free article. Review.

39

P21/WAF1 mutation and drug resistance to paclitaxel in locally advanced breast cancer.

Chrisanthar R, Knappskog S, Staalesen V, Lillehaug JR, Lønning PE. Chrisanthar R, et al. Int J Cancer. 2007 Jun 15;120(12):2749. doi: 10.1002/ijc.22595. Int J Cancer. 2007. PMID: 17315192 No abstract available.

40

RACK1 regulates Ki-Ras-mediated signaling and morphological transformation of NIH 3T3 cells.

Bjørndal B, Myklebust LM, Rosendal KR, Myromslien FD, Lorens JB, Nolan G, Bruland O, Lillehaug JR. Bjørndal B, et al. Int J Cancer. 2007 Mar 1;120(5):961-9. doi: 10.1002/ijc.22373. Int J Cancer. 2007. PMID: 17149700

41

The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer.

Staalesen V, Knappskog S, Chrisanthar R, Nordgard SH, Løkkevik E, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Gram IT, Kristensen VN, Børresen-Dale AL, Lillehaug JR, Lønning PE. Staalesen V, et al. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6000-4. doi: 10.1158/1078-0432.CCR-05-2822. Clin Cancer Res. 2006. PMID: 17062672

42

A novel type of deletion in the CDKN2A gene identified in a melanoma-prone family.

Knappskog S, Geisler J, Arnesen T, Lillehaug JR, Lønning PE. Knappskog S, et al. Genes Chromosomes Cancer. 2006 Dec;45(12):1155-63. doi: 10.1002/gcc.20379. Genes Chromosomes Cancer. 2006. PMID: 17001621

43

Gene expression in poorly differentiated papillary thyroid carcinomas.

Fluge Ø, Bruland O, Akslen LA, Lillehaug JR, Varhaug JE. Fluge Ø, et al. Thyroid. 2006 Feb;16(2):161-75. doi: 10.1089/thy.2006.16.161. Thyroid. 2006. PMID: 16676402

44

Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase.

Arnesen T, Betts MJ, Pendino F, Liberles DA, Anderson D, Caro J, Kong X, Varhaug JE, Lillehaug JR. Arnesen T, et al. BMC Biochem. 2006 Apr 25;7:13. doi: 10.1186/1471-2091-7-13. BMC Biochem. 2006. PMID: 16638120 Free PMC article.

45

Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex.

Arnesen T, Gromyko D, Pendino F, Ryningen A, Varhaug JE, Lillehaug JR. Arnesen T, et al. Oncogene. 2006 Jul 20;25(31):4350-60. doi: 10.1038/sj.onc.1209469. Epub 2006 Mar 6. Oncogene. 2006. PMID: 16518407

46

Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex.

Arnesen T, Anderson D, Torsvik J, Halseth HB, Varhaug JE, Lillehaug JR. Arnesen T, et al. Gene. 2006 Apr 26;371(2):291-5. doi: 10.1016/j.gene.2005.12.008. Epub 2006 Feb 28. Gene. 2006. PMID: 16507339

47

Nuclear localisation of endogenous SUMO-1-modified PDGF-C in human thyroid tissue and cell lines.

Reigstad LJ, Martinez A, Varhaug JE, Lillehaug JR. Reigstad LJ, et al. Exp Cell Res. 2006 Apr 1;312(6):782-95. doi: 10.1016/j.yexcr.2005.11.035. Epub 2006 Jan 26. Exp Cell Res. 2006. PMID: 16443219

48

Identification of a copper-repressible C-type heme protein of Methylococcus capsulatus (Bath). A member of a novel group of the bacterial di-heme cytochrome c peroxidase family of proteins.

Karlsen OA, Kindingstad L, Angelskår SM, Bruseth LJ, Straume D, Puntervoll P, Fjellbirkeland A, Lillehaug JR, Jensen HB. Karlsen OA, et al. FEBS J. 2005 Dec;272(24):6324-35. doi: 10.1111/j.1742-4658.2005.05020.x. FEBS J. 2005. PMID: 16336269 Free article.

49

Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools.

Berven FS, Karlsen OA, Straume AH, Flikka K, Murrell JC, Fjellbirkeland A, Lillehaug JR, Eidhammer I, Jensen HB. Berven FS, et al. Arch Microbiol. 2006 Feb;184(6):362-77. doi: 10.1007/s00203-005-0055-7. Epub 2005 Nov 26. Arch Microbiol. 2006. PMID: 16311759

50

Interaction between HIF-1 alpha (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 alpha.

Arnesen T, Kong X, Evjenth R, Gromyko D, Varhaug JE, Lin Z, Sang N, Caro J, Lillehaug JR. Arnesen T, et al. FEBS Lett. 2005 Nov 21;579(28):6428-32. doi: 10.1016/j.febslet.2005.10.036. Epub 2005 Nov 2. FEBS Lett. 2005. PMID: 16288748 Free PMC article.

51

Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family.

Reigstad LJ, Varhaug JE, Lillehaug JR. Reigstad LJ, et al. FEBS J. 2005 Nov;272(22):5723-41. doi: 10.1111/j.1742-4658.2005.04989.x. FEBS J. 2005. PMID: 16279938 Free article. Review.

52

Characterization of a prokaryotic haemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath).

Karlsen OA, Ramsevik L, Bruseth LJ, Larsen Ø, Brenner A, Berven FS, Jensen HB, Lillehaug JR. Karlsen OA, et al. FEBS J. 2005 May;272(10):2428-40. doi: 10.1111/j.1742-4658.2005.04663.x. FEBS J. 2005. PMID: 15885093 Free article.

53

Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.

Arnesen T, Anderson D, Baldersheim C, Lanotte M, Varhaug JE, Lillehaug JR. Arnesen T, et al. Biochem J. 2005 Mar 15;386(Pt 3):433-43. doi: 10.1042/BJ20041071. Biochem J. 2005. PMID: 15496142 Free PMC article.

54

Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath).

Ward N, Larsen Ø, Sakwa J, Bruseth L, Khouri H, Durkin AS, Dimitrov G, Jiang L, Scanlan D, Kang KH, Lewis M, Nelson KE, Methé B, Wu M, Heidelberg JF, Paulsen IT, Fouts D, Ravel J, Tettelin H, Ren Q, Read T, DeBoy RT, Seshadri R, Salzberg SL, Jensen HB, Birkeland NK, Nelson WC, Dodson RJ, Grindhaug SH, Holt I, Eidhammer I, Jonasen I, Vanaken S, Utterback T, Feldblyum TV, Fraser CM, Lillehaug JR, Eisen JA. Ward N, et al. PLoS Biol. 2004 Oct;2(10):e303. doi: 10.1371/journal.pbio.0020303. Epub 2004 Sep 21. PLoS Biol. 2004. PMID: 15383840 Free PMC article.

55

Alternative splicing and mutation status of CHEK2 in stage III breast cancer.

Staalesen V, Falck J, Geisler S, Bartkova J, Børresen-Dale AL, Lukas J, Lillehaug JR, Bartek J, Lønning PE. Staalesen V, et al. Oncogene. 2004 Nov 4;23(52):8535-44. doi: 10.1038/sj.onc.1207928. Oncogene. 2004. PMID: 15361853

56

Genetic and epigenetic changes in p21 and p21B do not correlate with resistance to doxorubicin or mitomycin and 5-fluorouracil in locally advanced breast cancer.

Staalesen V, Leirvaag B, Lillehaug JR, Lønning PE. Staalesen V, et al. Clin Cancer Res. 2004 May 15;10(10):3438-43. doi: 10.1158/1078-0432.CCR-03-0796. Clin Cancer Res. 2004. PMID: 15161699

57

Mutations of the cell cycle regulatory genes p16INK4A and p21WAF1 and the metastasis-inducing gene S100A4 are infrequent and unrelated to p53 tumour suppressor gene status and data on survival in oropharyngeal squamous cell carcinomas.

Ibrahim SO, Lillehaug JR, Vasstrand EN. Ibrahim SO, et al. Anticancer Res. 2003 Nov-Dec;23(6C):4593-600. Anticancer Res. 2003. PMID: 14981901

58

Increased expression of genes encoding mitochondrial proteins in papillary thyroid carcinomas.

Haugen DR, Fluge Ø, Reigstad LJ, Varhaug JE, Lillehaug JR. Haugen DR, et al. Thyroid. 2003 Jul;13(7):613-20. doi: 10.1089/105072503322239943. Thyroid. 2003. PMID: 12964965

59

Expression and purification of receptor for activated C-kinase 1 (RACK1).

Bjørndal B, Trave G, Hageberg I, Lillehaug JR, Raae AJ. Bjørndal B, et al. Protein Expr Purif. 2003 Sep;31(1):47-55. doi: 10.1016/s1046-5928(03)00135-9. Protein Expr Purif. 2003. PMID: 12963340

60

Participation of phospholipase D and alpha/beta-protein kinase C in growth factor-induced signalling in C3H10T1/2 fibroblasts.

Thorsen VA, Vorland M, Bjørndal B, Bruland O, Holmsen H, Lillehaug JR. Thorsen VA, et al. Biochim Biophys Acta. 2003 Jun 10;1632(1-3):62-71. doi: 10.1016/s1388-1981(03)00063-5. Biochim Biophys Acta. 2003. PMID: 12782152

61

Platelet-derived growth factor (PDGF)-C, a PDGF family member with a vascular endothelial growth factor-like structure.

Reigstad LJ, Sande HM, Fluge Ø, Bruland O, Muga A, Varhaug JE, Martinez A, Lillehaug JR. Reigstad LJ, et al. J Biol Chem. 2003 May 9;278(19):17114-20. doi: 10.1074/jbc.M301728200. Epub 2003 Feb 20. J Biol Chem. 2003. PMID: 12598536 Free article.

62

Gene expression profile in oral squamous cell carcinomas and matching normal oral mucosal tissues from black Africans and white Caucasians: the case of the Sudan vs. Norway.

Ibrahim SO, Aarsaether N, Holsve MK, Kross KW, Heimdal JH, Aarstad JH, Liavaag PG, Elgindi OA, Johannessen AC, Lillehaug JR, Vasstrand EN. Ibrahim SO, et al. Oral Oncol. 2003 Jan;39(1):37-48. doi: 10.1016/s1368-8375(02)00018-0. Oral Oncol. 2003. PMID: 12457720

63

Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid.

Bjørndal B, Helleland C, Bøe SO, Gudbrandsen OA, Kalland KH, Bohov P, Berge RK, Lillehaug JR. Bjørndal B, et al. J Lipid Res. 2002 Oct;43(10):1630-40. doi: 10.1194/jlr.m100406-jlr200. J Lipid Res. 2002. PMID: 12364547 Free article.

64

Mutations of the cell cycle arrest gene p21WAF1, but not the metastasis-inducing gene S100A4, are frequent in oral squamous cell carcinomas from Sudanese toombak dippers and non-snuff-dippers from the Sudan, Scandinavia, USA and UK.

Ibrahim SO, Lillehaug JR, Dolphine O, Johnson NW, Warnakulasuriya KA, Vasstrand EN. Ibrahim SO, et al. Anticancer Res. 2002 May-Jun;22(3):1445-51. Anticancer Res. 2002. PMID: 12168821

65

NATH, a novel gene overexpressed in papillary thyroid carcinomas.

Fluge Ø, Bruland O, Akslen LA, Varhaug JE, Lillehaug JR. Fluge Ø, et al. Oncogene. 2002 Aug 1;21(33):5056-68. doi: 10.1038/sj.onc.1205687. Oncogene. 2002. PMID: 12140756

66

Difference in patterns of Met expression in papillary thyroid carcinomas and nonneoplastic thyroid tissue.

Fluge Ø, Haugen DR, Lillehaug JR, Varhaug JE. Fluge Ø, et al. World J Surg. 2001 May;25(5):623-31. doi: 10.1007/s002680020167. World J Surg. 2001. PMID: 11369990

67

Expression and alternative splicing of c-ret RNA in papillary thyroid carcinomas.

Fluge O, Haugen DR, Akslen LA, Marstad A, Santoro M, Fusco A, Varhaug JE, Lillehaug JR. Fluge O, et al. Oncogene. 2001 Feb 15;20(7):885-92. doi: 10.1038/sj.onc.1204161. Oncogene. 2001. PMID: 11314023

68

Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer.

Geisler S, Lønning PE, Aas T, Johnsen H, Fluge O, Haugen DF, Lillehaug JR, Akslen LA, Børresen-Dale AL. Geisler S, et al. Cancer Res. 2001 Mar 15;61(6):2505-12. Cancer Res. 2001. PMID: 11289122 Clinical Trial.

69

Ectopic expression of Bcl-2 switches over nuclear signalling for cAMP-induced apoptosis to granulocytic differentiation.

Séité P, Ruchaud S, Hillion J, Gendron MC, Bruland O, Ségal-Bendirdjian E, Doskeland SO, Lillehaug JR, Lanotte M. Séité P, et al. Cell Death Differ. 2000 Nov;7(11):1081-9. doi: 10.1038/sj.cdd.4400730. Cell Death Differ. 2000. PMID: 11139282

70

Expression of a peptide binding to receptor for activated C-kinase (RACK1) inhibits phorbol myristoyl acetate-stimulated phospholipase D activity in C3H/10T1/2 cells: dissociation of phospholipase D-mediated phosphatidylcholine breakdown from its synthesis.

Thorsen VA, Bjørndal B, Nolan G, Fukami MH, Bruland O, Lillehaug JR, Holmsen H. Thorsen VA, et al. Biochim Biophys Acta. 2000 Sep 27;1487(2-3):163-76. doi: 10.1016/s1388-1981(00)00092-5. Biochim Biophys Acta. 2000. PMID: 11018469

71

Expression of heregulins and associations with the ErbB family of tyrosine kinase receptors in papillary thyroid carcinomas.

Fluge O, Akslen LA, Haugen DR, Varhaug JE, Lillehaug JR. Fluge O, et al. Int J Cancer. 2000 Sep 15;87(6):763-70. doi: 10.1002/1097-0215(20000915)87:6<763::aid-ijc1>3.0.co;2-t. Int J Cancer. 2000. PMID: 10956383

72

Differential TPA and PDGF-BB effects on subcellular localisation of PKC alpha and beta I in C3H/10T1/2 cells.

Bjłrndal B, Helleland C, Lillehaug JR. Bjłrndal B, et al. Anticancer Res. 2000 Jul-Aug;20(4):2633-40. Anticancer Res. 2000. PMID: 10953336

73

A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4-R2, blocks RARA and wild-type PML/RARA transcriptional activities.

Duprez E, Benoit G, Flexor M, Lillehaug JR, Lanotte M. Duprez E, et al. Leukemia. 2000 Feb;14(2):255-61. doi: 10.1038/sj.leu.2401683. Leukemia. 2000. PMID: 10673742

74

Expression of biomarkers (p53, transforming growth factor alpha, epidermal growth factor receptor, c-erbB-2/neu and the proliferative cell nuclear antigen) in oropharyngeal squamous cell carcinomas.

Ibrahim SO, Lillehaug JR, Johannessen AC, Liavaag PG, Nilsen R, Vasstrand EN. Ibrahim SO, et al. Oral Oncol. 1999 May;35(3):302-13. doi: 10.1016/s1368-8375(98)00120-1. Oral Oncol. 1999. PMID: 10621852

75

Enhanced expression of EGF receptor and low frequency of ras mutations in X-ray-induced rat thyroid tumours.

Haugen DR, Lillehaug JR, Akslen LA. Haugen DR, et al. Virchows Arch. 1999 Oct;435(4):434-41. doi: 10.1007/pl00008191. Virchows Arch. 1999. PMID: 10526008

76

Mutations of the p53 gene in oral squamous-cell carcinomas from Sudanese dippers of nitrosamine-rich toombak and non-snuff-dippers from the Sudan and Scandinavia.

Ibrahim SO, Vasstrand EN, Johannessen AC, Idris AM, Magnusson B, Nilsen R, Lillehaug JR. Ibrahim SO, et al. Int J Cancer. 1999 May 17;81(4):527-34. doi: 10.1002/(sici)1097-0215(19990517)81:4<527::aid-ijc4>3.0.co;2-2. Int J Cancer. 1999. PMID: 10225439 Free article.

77

Early modulation of genes encoding peroxisomal and mitochondrial beta-oxidation enzymes by 3-thia fatty acids.

Vaagenes H, Madsen L, Asiedu DK, Lillehaug JR, Berge RK. Vaagenes H, et al. Biochem Pharmacol. 1998 Dec 15;56(12):1571-82. doi: 10.1016/s0006-2952(98)00193-2. Biochem Pharmacol. 1998. PMID: 9973177

78

The Swedish snus and the Sudanese toombak: are they different?

Idris AM, Ibrahim SO, Vasstrand EN, Johannessen AC, Lillehaug JR, Magnusson B, Wallström M, Hirsch JM, Nilsen R. Idris AM, et al. Oral Oncol. 1998 Nov;34(6):558-66. doi: 10.1016/s1368-8375(98)00047-5. Oral Oncol. 1998. PMID: 9930371 Review.

79

Choline derived from the phosphatidylcholine specific phospholipase D is not directly available for the CDP choline pathway in phorbol ester-treated C3H10T1/2 Cl 8 fibroblasts.

Thorsen VA, Bruland O, Lillehaug JR, Holmsen H. Thorsen VA, et al. Mol Cell Biochem. 1998 Oct;187(1-2):147-54. doi: 10.1023/a:1006813524791. Mol Cell Biochem. 1998. PMID: 9788752

80

[Diagnostic molecular biology in solid tumors--thyroid gland].

Faksvåg Haugen DR, Varhaug JE, Akslen LA, Lillehaug JR. Faksvåg Haugen DR, et al. Tidsskr Nor Laegeforen. 1998 May 30;118(14):2199-203. Tidsskr Nor Laegeforen. 1998. PMID: 9656818 Review. Norwegian.

81

Expression of c-erbB proto-oncogene family members in squamous cell carcinoma of the head and neck.

Ibrahim SO, Vasstrand EN, Liavaag PG, Johannessen AC, Lillehaug JR. Ibrahim SO, et al. Anticancer Res. 1997 Nov-Dec;17(6D):4539-46. Anticancer Res. 1997. PMID: 9494565

82

Immunohistochemical detection of p53 in archival formalin-fixed tissues of lip and intraoral squamous cell carcinomas from Norway.

Ibrahim SO, Johannessen AC, Vasstrand EN, Lillehaug JR, Nilsen R. Ibrahim SO, et al. APMIS. 1997 Oct;105(10):757-64. doi: 10.1111/j.1699-0463.1997.tb05081.x. APMIS. 1997. PMID: 9368590

83

1-(Carboxymethylthio)tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10T1/2 cells.

Helleland C, Eiane SA, Berge RK, Holmsen H, Lillehaug JR. Helleland C, et al. Exp Cell Res. 1997 Oct 10;236(1):330-40. doi: 10.1006/excr.1997.3697. Exp Cell Res. 1997. PMID: 9344614

84

cAMP signalling is decisive for recovery of nuclear bodies (PODs) during maturation of RA-resistant t(15;17) promyelocytic leukemia NB4 cells expressing PML-RAR alpha.

Duprez E, Lillehaug JR, Naoe T, Lanotte M. Duprez E, et al. Oncogene. 1996 Jun 6;12(11):2451-9. Oncogene. 1996. PMID: 8649787

85

Differential changes of retinoid-X-receptor (RXR alpha) and its RAR alpha and PML-RAR alpha partners induced by retinoic acid and cAMP distinguish maturation sensitive and resistant t(15;17) promyelocytic leukemia NB4 cells.

Duprez E, Lillehaug JR, Gaub MP, Lanotte M. Duprez E, et al. Oncogene. 1996 Jun 6;12(11):2443-50. Oncogene. 1996. PMID: 8649786

86

Expression of c-erbB-3 and c-erbB-4 proteins in papillary thyroid carcinomas.

Haugen DR, Akslen LA, Varhaug JE, Lillehaug JR. Haugen DR, et al. Cancer Res. 1996 Mar 15;56(6):1184-8. Cancer Res. 1996. PMID: 8640794

87

Cytoplasmic localization of EGF receptor in papillary thyroid carcinomas: association with the 150-kDa receptor form.

Ness GO, Haugen DR, Varhaug JE, Akslen LA, Lillehaug JR. Ness GO, et al. Int J Cancer. 1996 Jan 17;65(2):161-7. doi: 10.1002/(SICI)1097-0215(19960117)65:2<161::AID-IJC6>3.0.CO;2-X. Int J Cancer. 1996. PMID: 8567111

88

Fatty acyl-CoA oxidase activity is induced before long-chain acyl-CoA hydrolase activity and acyl-CoA binding protein in liver of rat treated with peroxisome proliferating 3-thia fatty acids.

Skorve J, Rosendal J, Vaagenes H, Knudsen J, Lillehaug JR, Berge RK. Skorve J, et al. Xenobiotica. 1995 Nov;25(11):1181-94. doi: 10.3109/00498259509046675. Xenobiotica. 1995. PMID: 8592868

89

Three-dimensional growth of glial cell lines affects growth factor and growth factor receptor mRNA levels.

Ness GO, Pedersen PH, Bjerkvig R, Laerum OD, Lillehaug JR. Ness GO, et al. Exp Cell Res. 1994 Sep;214(1):433-6. doi: 10.1006/excr.1994.1277. Exp Cell Res. 1994. PMID: 8082746

90

Coordinate induction of hepatic fatty acyl-CoA oxidase and P4504A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulphur-substituted fatty acid analogues.

Demoz A, Vaagenes H, Aarsaether N, Hvattum E, Skorve J, Göttlicher M, Lillehaug JR, Gibson GG, Gustafsson JA, Hood S, et al. Demoz A, et al. Xenobiotica. 1994 Sep;24(9):943-56. doi: 10.3109/00498259409043292. Xenobiotica. 1994. PMID: 7810175

91

Time-course study of 1,25-(OH)2-vitamin D3 induction of homologous receptor and c-myc in nontransformed and transformed C3H/10T1/2 cell clones.

Paatero GI, Trydal T, Karlstedt KA, Aarskog D, Lillehaug JR. Paatero GI, et al. Int J Biochem. 1994 Mar;26(3):367-74. doi: 10.1016/0020-711x(94)90056-6. Int J Biochem. 1994. PMID: 8187933

92

Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-alpha, bFGF, IL-2] on glioma spheroid growth, migration and invasion.

Pedersen PH, Ness GO, Engebraaten O, Bjerkvig R, Lillehaug JR, Laerum OD. Pedersen PH, et al. Int J Cancer. 1994 Jan 15;56(2):255-61. doi: 10.1002/ijc.2910560219. Int J Cancer. 1994. PMID: 8314309

93

Evidence against involvement of APC mutation in papillary thyroid carcinoma.

Curtis L, Wyllie AH, Shaw JJ, Williams GT, Radulescu A, DeMicco C, Haugen DR, Varhaug JE, Lillehaug JR, Wynford-Thomas D. Curtis L, et al. Eur J Cancer. 1994;30A(7):984-7. doi: 10.1016/0959-8049(94)90129-5. Eur J Cancer. 1994. PMID: 7946597

94

Growth requirements and oncogene expression in the human thyroid cell line SGHTL-34.

Ness GO, Aasland R, Lillehaug JR. Ness GO, et al. APMIS. 1993 Oct;101(10):767-76. doi: 10.1111/j.1699-0463.1993.tb00178.x. APMIS. 1993. PMID: 7903543

95

Analysis of 1alpha,25-dihydroxyvitamin D3 receptor in cell extracts with low protein concentration.

Trydal T, Aksnes L, Lillehaug JR, Aarskog D. Trydal T, et al. J Steroid Biochem Mol Biol. 1993 Sep;46(3):349-54. doi: 10.1016/0960-0760(93)90224-k. J Steroid Biochem Mol Biol. 1993. PMID: 9831483

96

Demonstration of a TGF-alpha-EGF-receptor autocrine loop and c-myc protein over-expression in papillary thyroid carcinomas.

Haugen DR, Akslen LA, Varhaug JE, Lillehaug JR. Haugen DR, et al. Int J Cancer. 1993 Aug 19;55(1):37-43. doi: 10.1002/ijc.2910550108. Int J Cancer. 1993. PMID: 8102129

97

Modulation of cell proliferation and cell cycle, and inhibition of cytokinesis by 1,25-dihydroxyvitamin D3 in C3H/10T1/2 fibroblasts.

Brackman D, Lillehaug JR, Aksnes L, Aarskog D. Brackman D, et al. J Steroid Biochem Mol Biol. 1993 Aug;46(2):155-62. doi: 10.1016/0960-0760(93)90290-d. J Steroid Biochem Mol Biol. 1993. PMID: 8664163

98

Inhibition and down-regulation of protein kinase C in cultured atrial myocytes: effects on distribution of specific granules and secretion of atrial natriuretic peptide.

Larsen TH, Myking O, Lillehaug JR, Saetersdal T. Larsen TH, et al. Mol Cell Endocrinol. 1993 Aug;94(2):173-81. doi: 10.1016/0303-7207(93)90166-h. Mol Cell Endocrinol. 1993. PMID: 8224521

99

Absence of PDGF-induced, PKC-independent c-fos expression in a chemically transformed C3H/10T1/2 cell clone.

Vassbotn FS, Skar R, Holmsen H, Lillehaug JR. Vassbotn FS, et al. Exp Cell Res. 1992 Sep;202(1):98-104. doi: 10.1016/0014-4827(92)90408-z. Exp Cell Res. 1992. PMID: 1380924

100

Reorganization of the cytoskeleton and morphological changes induced by 1,25-dihydroxyvitamin D3 in C3H/10T1/2 mouse embryo fibroblasts: relation to inhibition of proliferation.

Brackman D, Trydal T, Lillehaug JR, Aarskog D. Brackman D, et al. Exp Cell Res. 1992 Aug;201(2):485-93. doi: 10.1016/0014-4827(92)90298-m. Exp Cell Res. 1992. PMID: 1639143

101

Expression of c-erbB-2 protein in papillary thyroid carcinomas.

Haugen DR, Akslen LA, Varhaug JE, Lillehaug JR. Haugen DR, et al. Br J Cancer. 1992 Jun;65(6):832-7. doi: 10.1038/bjc.1992.177. Br J Cancer. 1992. PMID: 1352125 Free PMC article.

102

Regulation of cell growth, c-myc mRNA, and 1,25-(OH)2 vitamin D3 receptor in C3H/10T1/2 mouse embryo fibroblasts by calcipotriol and 1,25-(OH)2 vitamin D3.

Trydal T, Lillehaug JR, Aksnes L, Aarskog D. Trydal T, et al. Acta Endocrinol (Copenh). 1992 Jan;126(1):75-9. doi: 10.1530/acta.0.1260075. Acta Endocrinol (Copenh). 1992. PMID: 1310564

103

A nonradioactive assay for N5-methyltetrahydrofolate-homocysteine methyltransferase (methionine synthase) based on o-phthaldialdehyde derivatization of methionine and fluorescence detection.

Garras A, Djurhuus R, Christensen B, Lillehaug JR, Ueland PM. Garras A, et al. Anal Biochem. 1991 Nov 15;199(1):112-8. doi: 10.1016/0003-2697(91)90277-z. Anal Biochem. 1991. PMID: 1807154

104

Effect of 1,25-(OH)2-vitamin D3 on growth, homologous receptor and c-myc regulation in C3H/10T1/2 cells.

Trydal T, Lillehaug JR, Aksnes L, Aarskog D. Trydal T, et al. Mol Cell Endocrinol. 1990 Dec 21;74(3):191-202. doi: 10.1016/0303-7207(90)90224-v. Mol Cell Endocrinol. 1990. PMID: 1965647

105

Co-expression of the genes encoding transforming growth factor-alpha and its receptor in papillary carcinomas of the thyroid.

Aasland R, Akslen LA, Varhaug JE, Lillehaug JR. Aasland R, et al. Int J Cancer. 1990 Sep 15;46(3):382-7. doi: 10.1002/ijc.2910460308. Int J Cancer. 1990. PMID: 1697567

106

Structural changes in the ribosomal genes of immortalized and transformed mouse embryo C3H/10T1/2 cell lines.

Oyan AM, Lillehaug JR. Oyan AM, et al. APMIS. 1990 Mar;98(3):212-20. doi: 10.1111/j.1699-0463.1990.tb01024.x. APMIS. 1990. PMID: 1969285

107

Absence of abnormalities of the c-erbB-1 and c-erbB-2 proto-oncogenes in human thyroid neoplasia.

Lemoine NR, Wyllie FS, Lillehaug JR, Staddon SL, Hughes CM, Aasland R, Shaw J, Varhaug JE, Brown CL, Gullick WJ, et al. Lemoine NR, et al. Eur J Cancer. 1990;26(7):777-9. doi: 10.1016/0277-5379(90)90149-n. Eur J Cancer. 1990. PMID: 2145893

108

Ouabain-resistant (Na+,K+)-ATPase enzyme activity in chemically induced ouabain-resistant C3H/10T1/2 cells.

Shibuya ML, Miura T, Lillehaug JR, Farley RA, Landolph JR. Shibuya ML, et al. Mol Toxicol. 1989 Apr-Jun;2(2):75-98. Mol Toxicol. 1989. PMID: 2562032

109

Expression of oncogenes in thyroid tumours: coexpression of c-erbB2/neu and c-erbB.

Aasland R, Lillehaug JR, Male R, Jøsendal O, Varhaug JE, Kleppe K. Aasland R, et al. Br J Cancer. 1988 Apr;57(4):358-63. doi: 10.1038/bjc.1988.82. Br J Cancer. 1988. PMID: 3390372 Free PMC article.

110

Growth support and toxicity of homocysteine and its effects on methionine metabolism in non-transformed and chemically transformed C3H/10T1/2 cells.

Djurhuus R, Svardal AM, Ueland PM, Male R, Lillehaug JR. Djurhuus R, et al. Carcinogenesis. 1988 Jan;9(1):9-16. doi: 10.1093/carcin/9.1.9. Carcinogenesis. 1988. PMID: 3335051

111

Evidence that neomycin inhibits binding of herpes simplex virus type 1 to the cellular receptor.

Langeland N, Holmsen H, Lillehaug JR, Haarr L. Langeland N, et al. J Virol. 1987 Nov;61(11):3388-93. doi: 10.1128/JVI.61.11.3388-3393.1987. J Virol. 1987. PMID: 2822948 Free PMC article.

112

Biological and biochemical characterization of cell lines derived from initiation-promotion transformed C3H/10T1/2 cells.

Male R, Bjerkvig R, Lillehaug JR. Male R, et al. Carcinogenesis. 1987 Oct;8(10):1375-83. doi: 10.1093/carcin/8.10.1375. Carcinogenesis. 1987. PMID: 3652375

113

Cell transformation and promoter activity of insulation oils in the Syrian hamster embryo cell and in the C3H/10T1/2 mouse embryo fibroblast test systems.

Aarsaether N, Lillehaug JR, Rivedal E, Sanner T. Aarsaether N, et al. J Toxicol Environ Health. 1987;20(1-2):173-85. doi: 10.1080/15287398709530970. J Toxicol Environ Health. 1987. PMID: 3806702

114

Ornithine decarboxylase activity in foetal rat brain cells and in the mouse embryo fibroblasts C3H/10T1/2 CL8 cells: differences in response to medium change and to the tumor promoter TPA.

Djurhuus R, Laerum OD, Lillehaug JR. Djurhuus R, et al. Int J Biochem. 1987;19(6):495-501. doi: 10.1016/0020-711x(87)90132-7. Int J Biochem. 1987. PMID: 3609441

115

Changes in polypeptide synthesis and glycosylation in mouse embryonic fibroblast C3H/10T1/2 Cl 8 cells caused by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.

Haarr L, Kleppe K, Lillehaug JR. Haarr L, et al. Biochim Biophys Acta. 1986 Dec 19;889(3):334-45. doi: 10.1016/0167-4889(86)90196-5. Biochim Biophys Acta. 1986. PMID: 3790579

116

Enhanced expression of c-myc and decreased expression of c-fos protooncogenes in chemically and radiation-transformed C3H/10T1/2 Cl 8 mouse embryo cell lines.

Shuin T, Billings PC, Lillehaug JR, Patierno SR, Roy-Burman P, Landolph JR. Shuin T, et al. Cancer Res. 1986 Oct;46(10):5302-11. Cancer Res. 1986. PMID: 2875790

117

Differential effects of chlorpromazine on secretion, protein phosphorylation and phosphoinositide metabolism in stimulated platelets.

Opstvedt A, Rongved S, Aarsaether N, Lillehaug JR, Holmsen H. Opstvedt A, et al. Biochem J. 1986 Aug 15;238(1):159-66. doi: 10.1042/bj2380159. Biochem J. 1986. PMID: 3026339 Free PMC article.

118

Disposition of endogenous homocysteine by mouse fibroblast C3H/10T1/2 Cl 8 and the chemically transformed C3H/10T1/2 MCA Cl 16 cells following methotrexate exposure.

Ueland PM, Refsum H, Male R, Lillehaug JR. Ueland PM, et al. J Natl Cancer Inst. 1986 Jul;77(1):283-9. J Natl Cancer Inst. 1986. PMID: 3459921

119

Peroxisome proliferators show tumor-promoting but no direct transforming activity in vitro.

Lillehaug JR, Aarsaether N, Berge RK, Male R. Lillehaug JR, et al. Int J Cancer. 1986 Jan 15;37(1):97-100. doi: 10.1002/ijc.2910370116. Int J Cancer. 1986. PMID: 3941024

120

The tumour promoter 12-O-tetradecanoylphorbol-13-acetate increases the activities of some peroxisome-associated enzymes in in vitro cell culture.

Lillehaug JR, Berge RK. Lillehaug JR, et al. Br J Cancer. 1986 Jan;53(1):121-7. doi: 10.1038/bjc.1986.17. Br J Cancer. 1986. PMID: 2868750 Free PMC article.

121

Tiadenol-mediated induction of peroxisomal enzymes in cultured C3H/10T1/2CL8 cells and in chemically transformed C3H/10T1/2 MCA16 cells.

Berge RK, Lillehaug JR. Berge RK, et al. Int J Cancer. 1985 Oct 15;36(4):489-94. doi: 10.1002/ijc.2910360413. Int J Cancer. 1985. PMID: 2864317

122

In vitro transformation and tumor promotion studies of styrene and styrene oxide.

Male R, Lillehaug JR, Djurhuus R, Pryme IF. Male R, et al. Carcinogenesis. 1985 Sep;6(9):1367-70. doi: 10.1093/carcin/6.9.1367. Carcinogenesis. 1985. PMID: 2411441

123

Purification and kinetic properties of polynucleotide kinase from rat testes.

Bosdal T, Lillehaug JR. Bosdal T, et al. Biochim Biophys Acta. 1985 Jun 18;840(2):280-6. doi: 10.1016/0304-4165(85)90129-1. Biochim Biophys Acta. 1985. PMID: 2986715

124

Xeroderma pigmentosum: in vitro complementation of DNA repair endonuclease.

Helland D, Kleppe R, Lillehaug JR, Kleppe K. Helland D, et al. Carcinogenesis. 1984 Jun;5(6):833-6. doi: 10.1093/carcin/5.6.833. Carcinogenesis. 1984. PMID: 6233045

125

The nuclear-associated endoplasmic reticulum is an early target for the action of the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate in C3H/10T1/2 fibroblasts.

Pryme IF, Lillehaug JR, Fjose A, Kleppe K. Pryme IF, et al. FEBS Lett. 1983 Feb 7;152(1):17-20. doi: 10.1016/0014-5793(83)80472-4. FEBS Lett. 1983. PMID: 6840272 Free article.

126

The specific appearance of a 65,000 dalton protein in the nuclear associated endoplasmic reticulum of Krebs II ascites cells early after treatment with the phorbol ester TPA.

Fjose A, Pryme IF, Lillehaug JR, Djurhuus R. Fjose A, et al. Carcinogenesis. 1983;4(7):811-5. doi: 10.1093/carcin/4.7.811. Carcinogenesis. 1983. PMID: 6872136

127

Comparative studies on tree-pollen allergens. VI. The effect of thermal denaturation on the reactivity of birch pollen (Betula verrucosa) allergens.

Vik H, Lillehaug JR. Vik H, et al. Int Arch Allergy Appl Immunol. 1983;71(1):47-52. Int Arch Allergy Appl Immunol. 1983. PMID: 6832844

128

The phorbol ester 12-0-tetradecanoyl-phorbol-13-acetate and stimulation of 3H-choline incorporation into endoplasmic reticulum membranes and other subcellular fractions of Krebs II ascites cells during in vitro incubation.

Fjose A, Pryme IF, Lillehaug JR. Fjose A, et al. Mol Cell Biochem. 1983;56(2):137-44. doi: 10.1007/BF00227214. Mol Cell Biochem. 1983. PMID: 6646113

129

Butylated hydroxytoluene: tumor-promoting activity in an in vitro two-stage carcinogenesis assay.

Djurhuus R, Lillehaug JR. Djurhuus R, et al. Bull Environ Contam Toxicol. 1982 Jul;29(1):115-20. doi: 10.1007/BF01606098. Bull Environ Contam Toxicol. 1982. PMID: 7115989 No abstract available.

130

Effect of diethylstilbestrol on the transformable mouse embryo fibroblast C3H/10T1/2C18 cells. Tumor promotion, cell growth, DNA synthesis, and ornithine decarboxylase.

Lillehaug JR, Djurhuus R. Lillehaug JR, et al. Carcinogenesis. 1982;3(7):797-9. doi: 10.1093/carcin/3.7.797. Carcinogenesis. 1982. PMID: 7116574

131

Effect of polyamines on enzymes involved in DNA repair.

Kleppe K, Osland A, Fosse V, Male R, Lossius I, Helland D, Lillehaug JR, Raae AJ, Kleppe RK, Nes IF. Kleppe K, et al. Med Biol. 1981 Dec;59(5-6):374-80. Med Biol. 1981. PMID: 6279978

132

[2-Step carcinogenesis. Significance of tumor promotors in the development of cancer].

Lillehaug JR. Lillehaug JR. Tidsskr Nor Laegeforen. 1980 Sep 10;100(25):1482-5. Tidsskr Nor Laegeforen. 1980. PMID: 7456021 Norwegian. No abstract available.

133

Establishment of epithelial cell lines from adult mouse regenerating liver.

Lillehaug JR, Mondal S, Heidelberger C. Lillehaug JR, et al. In Vitro. 1979 Nov;15(11):910-6. doi: 10.1007/BF02618048. In Vitro. 1979. PMID: 540917

134

Polynucleotide kinase.

Kleppe K, Lillehaug JR. Kleppe K, et al. Adv Enzymol Relat Areas Mol Biol. 1979;48:245-75. doi: 10.1002/9780470122938.ch5. Adv Enzymol Relat Areas Mol Biol. 1979. PMID: 216242 Review. No abstract available.

135

Inhibition of T4 polynucleotide kinase by the ATP analog, beta, gamma-imidoadenylyl 5'-triphosphate.

Lillehaug JR. Lillehaug JR. Biochim Biophys Acta. 1978 Aug 7;525(2):357-63. doi: 10.1016/0005-2744(78)90230-9. Biochim Biophys Acta. 1978. PMID: 210816

136

Physicochemical properties of T4 polynucleotide kinase.

Lillehaug JR. Lillehaug JR. Eur J Biochem. 1977 Mar 1;73(2):499-506. doi: 10.1111/j.1432-1033.1977.tb11343.x. Eur J Biochem. 1977. PMID: 191256 Free article.

137

Phosphorylation of tRNA by T4 polynucleotide kinase.

Lillehaug JR, Kleppe K. Lillehaug JR, et al. Nucleic Acids Res. 1977 Feb;4(2):373-80. doi: 10.1093/nar/4.2.373. Nucleic Acids Res. 1977. PMID: 190592 Free PMC article.

138

Enzymatic cleavage of m7 GDP from eucaryotic mRNA.

Abraham KA, Lillehaug JR. Abraham KA, et al. FEBS Lett. 1976 Nov 15;72(1):49-52. doi: 10.1016/0014-5793(76)80896-4. FEBS Lett. 1976. PMID: 992089 Free article. No abstract available.

139

Phosphorylation of double-stranded DNAs by T4 polynucleotide kinase.

Lillehaug JR, Kleppe RK, Kleppe K. Lillehaug JR, et al. Biochemistry. 1976 May 4;15(9):1858-65. doi: 10.1021/bi00654a011. Biochemistry. 1976. PMID: 178357

140

Kinetics and specificity of T4 polynucleotide kinase.

Lillehaug JR, Kleppe K. Lillehaug JR, et al. Biochemistry. 1975 Mar 25;14(6):1221-5. doi: 10.1021/bi00677a020. Biochemistry. 1975. PMID: 235284

141

Effect of salts and polyamines on T4 polynucleotide kinase.

Lillehaug JR, Kleppe K. Lillehaug JR, et al. Biochemistry. 1975 Mar 25;14(6):1225-9. doi: 10.1021/bi00677a021. Biochemistry. 1975. PMID: 164211

142

Preparation and separation of d(pT)-10-n oligonucleotides.

Raae AJ, Lillehaug JR, Kleppe RK, Kleppe K. Raae AJ, et al. Nucleic Acids Res. 1975 Mar;2(3):423-9. doi: 10.1093/nar/2.3.423. Nucleic Acids Res. 1975. PMID: 1129141 Free PMC article.

143

DNA polymerase I from Acinetobacter calcoaceticus: enzymatic properties.

Nes IF, Lillehaug JR, Kleppe K. Nes IF, et al. Eur J Biochem. 1974 Dec 16;50(1):167-75. doi: 10.1111/j.1432-1033.1974.tb03884.x. Eur J Biochem. 1974. PMID: 4452356 Free article. No abstract available.

144

Effect of pH on incorporation of ribonucleotides into dna by DNA polymerase I.

Lillehaug JR, Kleppe K. Lillehaug JR, et al. FEBS Lett. 1974 Apr 1;40(2):339-42. doi: 10.1016/0014-5793(74)80258-9. FEBS Lett. 1974. PMID: 4604394 Free article. No abstract available.

145

Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase.

Panet A, van de Sande JH, Loewen PC, Khorana HG, Raae AJ, Lillehaug JR, Kleppe K. Panet A, et al. Biochemistry. 1973 Dec 4;12(25):5045-50. doi: 10.1021/bi00749a003. Biochemistry. 1973. PMID: 4366077 No abstract available.

146

Reaction of biological thiols with the tumor inhibitor jatrophone. Inhibition of RNA polymerase.

Lillehaug JR, Kleppe K, Sigel CW, Kupchan SM. Lillehaug JR, et al. Biochim Biophys Acta. 1973 Nov 15;327(1):92-100. doi: 10.1016/0005-2744(73)90106-x. Biochim Biophys Acta. 1973. PMID: 4589016 No abstract available.

147

In vivo and in vitro transcription of T7 early genes by T7 RNA polymerase.

Lillehaug JR, Helland D, Sjöberg NO. Lillehaug JR, et al. FEBS Lett. 1973 Jul 15;33(3):335-8. doi: 10.1016/0014-5793(73)80224-8. FEBS Lett. 1973. PMID: 4580764 Free article. No abstract available.

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