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2022 3
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Page 1
Optimizing multifunctional fluorescent ligands for intracellular labeling.
Kumar P, Vevea JD, Tkachuk AN, Campbell KR, Watson ET, Ayala AX, Grimm JB, Chapman ER, Solecki DJ, Lavis LD. Kumar P, et al. Proc Natl Acad Sci U S A. 2025 Nov 4;122(44):e2510046122. doi: 10.1073/pnas.2510046122. Epub 2025 Oct 27. Proc Natl Acad Sci U S A. 2025. PMID: 41144676 Free PMC article.
Conservation and divergence of metabolic phenotypes between patient tumours and matched xenografts.
Rao AD, Cai L, Snyman M, Walsdorf RE, Li X, Wix SN, Gard G, Brown AB, Kim J, Santos Patricio J, Muh S, Martin Sandoval M, Zacharias LG, Heimdal KA, Gu W, Homsi J, Tillman B, Sharma R, Vandergriff TW, Solmonson A, Faubert B, Mathews TP, Morrison SJ, DeBerardinis RJ, Gill JG. Rao AD, et al. Nat Metab. 2025 Aug;7(8):1703-1713. doi: 10.1038/s42255-025-01338-2. Epub 2025 Jul 29. Nat Metab. 2025. PMID: 40731149 Free PMC article.
Nucleosome spacing can fine-tune higher-order chromatin assembly.
Chen L, Maristany MJ, Farr SE, Luo J, Gibson BA, Doolittle LK, Espinosa JR, Huertas J, Redding S, Collepardo-Guevara R, Rosen MK. Chen L, et al. Nat Commun. 2025 Jul 9;16(1):6315. doi: 10.1038/s41467-025-61482-x. Nat Commun. 2025. PMID: 40628730 Free PMC article.
Cross-reactive sarbecovirus antibodies induced by mosaic RBD nanoparticles.
Fan C, Keeffe JR, Malecek KE, Cohen AA, West AP Jr, Baharani VA, Rorick AV, Gao H, Gnanapragasam PNP, Rho S, Alvarez J, Segovia LN, Hatziioannou T, Bieniasz PD, Bjorkman PJ. Fan C, et al. Proc Natl Acad Sci U S A. 2025 May 27;122(21):e2501637122. doi: 10.1073/pnas.2501637122. Epub 2025 May 22. Proc Natl Acad Sci U S A. 2025. PMID: 40402246 Free PMC article.
Structure of the lens MP20 mediated adhesive junction.
Nicolas WJ, Shiriaeva A, Martynowycz MW, Grey AC, Ruma YN, Donaldson PJ, Gonen T. Nicolas WJ, et al. Nat Commun. 2025 Mar 26;16(1):2977. doi: 10.1038/s41467-025-57903-6. Nat Commun. 2025. PMID: 40140346 Free PMC article.
Structural polymorphism and diversity of human segmental duplications.
Jeong H, Dishuck PC, Yoo D, Harvey WT, Munson KM, Lewis AP, Kordosky J, Garcia GH; Human Genome Structural Variation Consortium (HGSVC); Yilmaz F, Hallast P, Lee C, Pastinen T, Eichler EE. Jeong H, et al. Nat Genet. 2025 Feb;57(2):390-401. doi: 10.1038/s41588-024-02051-8. Epub 2025 Jan 8. Nat Genet. 2025. PMID: 39779957 Free PMC article.
Glutamine sensing licenses cholesterol synthesis.
Garcia BM, Melchinger P, Medeiros T, Hendrix S, Prabhu K, Corrado M, Kingma J, Gorbatenko A, Deshwal S, Veronese M, Scorrano L, Pearce E, Giavalisco P, Zelcer N, Pernas L. Garcia BM, et al. EMBO J. 2024 Dec;43(23):5837-5856. doi: 10.1038/s44318-024-00269-0. Epub 2024 Oct 21. EMBO J. 2024. PMID: 39433901 Free PMC article.
A large colonial choanoflagellate from Mono Lake harbors live bacteria.
Hake KH, West PT, McDonald K, Laundon D, Reyes-Rivera J, Garcia De Las Bayonas A, Feng C, Burkhardt P, Richter DJ, Banfield JF, King N. Hake KH, et al. mBio. 2024 Sep 11;15(9):e0162324. doi: 10.1128/mbio.01623-24. Epub 2024 Aug 14. mBio. 2024. PMID: 39140743 Free PMC article.
Matriglycan maintains t-tubule structural integrity in cardiac muscle.
Hord JM, Anderson ME, Prouty SJ, Melton S, Gastel Z, Zimmerman K, Weiss RM, Campbell KP. Hord JM, et al. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2402890121. doi: 10.1073/pnas.2402890121. Epub 2024 May 21. Proc Natl Acad Sci U S A. 2024. PMID: 38771868 Free PMC article.
Intranasal neomycin evokes broad-spectrum antiviral immunity in the upper respiratory tract.
Mao T, Kim J, Peña-Hernández MA, Valle G, Moriyama M, Luyten S, Ott IM, Gomez-Calvo ML, Gehlhausen JR, Baker E, Israelow B, Slade M, Sharma L, Liu W, Ryu C, Korde A, Lee CJ, Silva Monteiro V, Lucas C, Dong H, Yang Y; Yale SARS-CoV-2 Genomic Surveillance Initiative; Gopinath S, Wilen CB, Palm N, Dela Cruz CS, Iwasaki A. Mao T, et al. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2319566121. doi: 10.1073/pnas.2319566121. Epub 2024 Apr 22. Proc Natl Acad Sci U S A. 2024. PMID: 38648490 Free PMC article.
The diverse genetic origins of a Classical period Greek army.
Reitsema LJ, Mittnik A, Kyle B, Catalano G, Fabbri PF, Kazmi ACS, Reinberger KL, Sineo L, Vassallo S, Bernardos R, Broomandkhoshbacht N, Callan K, Candilio F, Cheronet O, Curtis E, Fernandes D, Lari M, Lawson AM, Mah M, Mallick S, Mandl K, Micco A, Modi A, Oppenheimer J, Özdogan KT, Rohland N, Stewardson K, Vai S, Vergata C, Workman JN, Zalzala F, Zaro V, Achilli A, Anagnostopoulos A, Capelli C, Constantinou V, Lancioni H, Olivieri A, Papadopoulou A, Psatha N, Semino O, Stamatoyannopoulos J, Valliannou I, Yannaki E, Lazaridis I, Patterson N, Ringbauer H, Caramelli D, Pinhasi R, Reich D. Reitsema LJ, et al. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2205272119. doi: 10.1073/pnas.2205272119. Epub 2022 Oct 3. Proc Natl Acad Sci U S A. 2022. PMID: 36191217 Free PMC article.
Neutralizing antibodies against the SARS-CoV-2 Delta and Omicron variants following heterologous CoronaVac plus BNT162b2 booster vaccination.
Pérez-Then E, Lucas C, Monteiro VS, Miric M, Brache V, Cochon L, Vogels CBF, Malik AA, De la Cruz E, Jorge A, De Los Santos M, Leon P, Breban MI, Billig K, Yildirim I, Pearson C, Downing R, Gagnon E, Muyombwe A, Razeq J, Campbell M, Ko AI, Omer SB, Grubaugh ND, Vermund SH, Iwasaki A. Pérez-Then E, et al. Nat Med. 2022 Mar;28(3):481-485. doi: 10.1038/s41591-022-01705-6. Epub 2022 Jan 20. Nat Med. 2022. PMID: 35051990 Free PMC article.