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Page 1
A molecular barcode and web-based data analysis tool to identify imported Plasmodium vivax malaria.
Trimarsanto H, Amato R, Pearson RD, Sutanto E, Noviyanti R, Trianty L, Marfurt J, Pava Z, Echeverry DF, Lopera-Mesa TM, Montenegro LM, Tobón-Castaño A, Grigg MJ, Barber B, William T, Anstey NM, Getachew S, Petros B, Aseffa A, Assefa A, Rahim AG, Chau NH, Hien TT, Alam MS, Khan WA, Ley B, Thriemer K, Wangchuck S, Hamedi Y, Adam I, Liu Y, Gao Q, Sriprawat K, Ferreira MU, Laman M, Barry A, Mueller I, Lacerda MVG, Llanos-Cuentas A, Krudsood S, Lon C, Mohammed R, Yilma D, Pereira DB, Espino FEJ, Chu CS, Vélez ID, Namaik-Larp C, Villegas MF, Green JA, Koh G, Rayner JC, Drury E, Gonçalves S, Simpson V, Miotto O, Miles A, White NJ, Nosten F, Kwiatkowski DP, Price RN, Auburn S. Trimarsanto H, et al. Among authors: nosten f. Commun Biol. 2022 Dec 23;5(1):1411. doi: 10.1038/s42003-022-04352-2. Commun Biol. 2022. PMID: 36564617 Free PMC article.
New antimalarials. A risk-benefit analysis.
Nosten F, Price RN. Nosten F, et al. Drug Saf. 1995 Apr;12(4):264-73. doi: 10.2165/00002018-199512040-00006. Drug Saf. 1995. PMID: 7646825 Review.
Comparison of oral artesunate and dihydroartemisinin antimalarial bioavailabilities in acute falciparum malaria.
Newton PN, van Vugt M, Teja-Isavadharm P, Siriyanonda D, Rasameesoroj M, Teerapong P, Ruangveerayuth R, Slight T, Nosten F, Suputtamongkol Y, Looareesuwan S, White NJ. Newton PN, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2002 Apr;46(4):1125-7. doi: 10.1128/AAC.46.4.1125-1127.2002. Antimicrob Agents Chemother. 2002. PMID: 11897605 Free PMC article. Clinical Trial.
Editorial: Maternal malaria: time for action.
Nosten F, McGready R, Looareesuwan S, White NJ. Nosten F, et al. Trop Med Int Health. 2003 Jun;8(6):485-7. doi: 10.1046/j.1365-3156.2003.01067.x. Trop Med Int Health. 2003. PMID: 12791053 Free article. No abstract available.
A systematic overview of published antimalarial drug trials.
Myint HY, Tipmanee P, Nosten F, Day NP, Pukrittayakamee S, Looareesuwan S, White NJ. Myint HY, et al. Among authors: nosten f. Trans R Soc Trop Med Hyg. 2004 Feb;98(2):73-81. doi: 10.1016/s0035-9203(03)00014-2. Trans R Soc Trop Med Hyg. 2004. PMID: 14964805 Review.
Field evaluation of a novel colorimetric method--double-site enzyme-linked lactate dehydrogenase immunodetection assay--to determine drug susceptibilities of Plasmodium falciparum clinical isolates from northwestern Thailand.
Brockman A, Singlam S, Phiaphun L, Looareesuwan S, White NJ, Nosten F. Brockman A, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2004 Apr;48(4):1426-9. doi: 10.1128/AAC.48.4.1426-1429.2004. Antimicrob Agents Chemother. 2004. PMID: 15047560 Free PMC article.
Randomized, controlled dose-optimization studies of dihydroartemisinin-piperaquine for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.
Ashley EA, Krudsood S, Phaiphun L, Srivilairit S, McGready R, Leowattana W, Hutagalung R, Wilairatana P, Brockman A, Looareesuwan S, Nosten F, White NJ. Ashley EA, et al. Among authors: nosten f. J Infect Dis. 2004 Nov 15;190(10):1773-82. doi: 10.1086/425015. Epub 2004 Oct 18. J Infect Dis. 2004. PMID: 15499533 Clinical Trial.
In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up.
Stepniewska K, Taylor WR, Mayxay M, Price R, Smithuis F, Guthmann JP, Barnes K, Myint HY, Adjuik M, Olliaro P, Pukrittayakamee S, Looareesuwan S, Hien TT, Farrar J, Nosten F, Day NP, White NJ. Stepniewska K, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2004 Nov;48(11):4271-80. doi: 10.1128/AAC.48.11.4271-4280.2004. Antimicrob Agents Chemother. 2004. PMID: 15504852 Free PMC article.
Malaria misconceptions.
Nosten F, McGready R, Ashley E, White NJ. Nosten F, et al. Lancet. 2005 Feb 19-25;365(9460):653. doi: 10.1016/S0140-6736(05)17938-0. Lancet. 2005. PMID: 15721465 No abstract available.
A randomized, controlled study of a simple, once-daily regimen of dihydroartemisinin-piperaquine for the treatment of uncomplicated, multidrug-resistant falciparum malaria.
Ashley EA, McGready R, Hutagalung R, Phaiphun L, Slight T, Proux S, Thwai KL, Barends M, Looareesuwan S, White NJ, Nosten F. Ashley EA, et al. Among authors: nosten f. Clin Infect Dis. 2005 Aug 15;41(4):425-32. doi: 10.1086/432011. Epub 2005 Jul 15. Clin Infect Dis. 2005. PMID: 16028147 Clinical Trial.
Are extensive T cell epitope polymorphisms in the Plasmodium falciparum circumsporozoite antigen, a leading sporozoite vaccine candidate, selected by immune pressure?
Kumkhaek C, Phra-Ek K, Rénia L, Singhasivanon P, Looareesuwan S, Hirunpetcharat C, White NJ, Brockman A, Grüner AC, Lebrun N, Alloueche A, Nosten F, Khusmith S, Snounou G. Kumkhaek C, et al. Among authors: nosten f. J Immunol. 2005 Sep 15;175(6):3935-9. doi: 10.4049/jimmunol.175.6.3935. J Immunol. 2005. PMID: 16148140
Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria.
Price RN, Uhlemann AC, van Vugt M, Brockman A, Hutagalung R, Nair S, Nash D, Singhasivanon P, Anderson TJ, Krishna S, White NJ, Nosten F. Price RN, et al. Among authors: nosten f. Clin Infect Dis. 2006 Jun 1;42(11):1570-7. doi: 10.1086/503423. Epub 2006 Apr 26. Clin Infect Dis. 2006. PMID: 16652314 Free PMC article. Clinical Trial.
Deployment of early diagnosis and mefloquine-artesunate treatment of falciparum malaria in Thailand: the Tak Malaria Initiative.
Carrara VI, Sirilak S, Thonglairuam J, Rojanawatsirivet C, Proux S, Gilbos V, Brockman A, Ashley EA, McGready R, Krudsood S, Leemingsawat S, Looareesuwan S, Singhasivanon P, White N, Nosten F. Carrara VI, et al. Among authors: nosten f. PLoS Med. 2006 Jun;3(6):e183. doi: 10.1371/journal.pmed.0030183. PLoS Med. 2006. PMID: 16719547 Free PMC article.
Malaria.
Ashley E, McGready R, Proux S, Nosten F. Ashley E, et al. Among authors: nosten f. Travel Med Infect Dis. 2006 May-Jul;4(3-4):159-73. doi: 10.1016/j.tmaid.2005.06.009. Epub 2005 Sep 19. Travel Med Infect Dis. 2006. PMID: 16887738 Review.
An open label randomized comparison of mefloquine-artesunate as separate tablets vs. a new co-formulated combination for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.
Ashley EA, Lwin KM, McGready R, Simon WH, Phaiphun L, Proux S, Wangseang N, Taylor W, Stepniewska K, Nawamaneerat W, Thwai KL, Barends M, Leowattana W, Olliaro P, Singhasivanon P, White NJ, Nosten F. Ashley EA, et al. Among authors: nosten f. Trop Med Int Health. 2006 Nov;11(11):1653-60. doi: 10.1111/j.1365-3156.2006.01724.x. Trop Med Int Health. 2006. PMID: 17054744 Free article. Clinical Trial.
How much fat is necessary to optimize lumefantrine oral bioavailability?
Ashley EA, Stepniewska K, Lindegårdh N, Annerberg A, Kham A, Brockman A, Singhasivanon P, White NJ, Nosten F. Ashley EA, et al. Among authors: nosten f. Trop Med Int Health. 2007 Feb;12(2):195-200. doi: 10.1111/j.1365-3156.2006.01784.x. Trop Med Int Health. 2007. PMID: 17300625 Free article. Clinical Trial.
Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites.
Imwong M, Snounou G, Pukrittayakamee S, Tanomsing N, Kim JR, Nandy A, Guthmann JP, Nosten F, Carlton J, Looareesuwan S, Nair S, Sudimack D, Day NP, Anderson TJ, White NJ. Imwong M, et al. Among authors: nosten f. J Infect Dis. 2007 Apr 1;195(7):927-33. doi: 10.1086/512241. Epub 2007 Feb 26. J Infect Dis. 2007. PMID: 17330781 Free article. Clinical Trial.
World Antimalarial Resistance Network I: clinical efficacy of antimalarial drugs.
Price RN, Dorsey G, Ashley EA, Barnes KI, Baird JK, d'Alessandro U, Guerin PJ, Laufer MK, Naidoo I, Nosten F, Olliaro P, Plowe CV, Ringwald P, Sibley CH, Stepniewska K, White NJ. Price RN, et al. Among authors: nosten f. Malar J. 2007 Sep 6;6:119. doi: 10.1186/1475-2875-6-119. Malar J. 2007. PMID: 17822532 Free PMC article.
Chloroquine resistant Plasmodium vivax: in vitro characterisation and association with molecular polymorphisms.
Suwanarusk R, Russell B, Chavchich M, Chalfein F, Kenangalem E, Kosaisavee V, Prasetyorini B, Piera KA, Barends M, Brockman A, Lek-Uthai U, Anstey NM, Tjitra E, Nosten F, Cheng Q, Price RN. Suwanarusk R, et al. Among authors: nosten f. PLoS One. 2007 Oct 31;2(10):e1089. doi: 10.1371/journal.pone.0001089. PLoS One. 2007. PMID: 17971853 Free PMC article.
Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar.
Imwong M, Pukrittayakamee S, Pongtavornpinyo W, Nakeesathit S, Nair S, Newton P, Nosten F, Anderson TJ, Dondorp A, Day NP, White NJ. Imwong M, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2008 Jul;52(7):2657-9. doi: 10.1128/AAC.01459-07. Epub 2008 Apr 28. Antimicrob Agents Chemother. 2008. PMID: 18443118 Free PMC article.
Plasmodium vivax trophozoites insensitive to chloroquine.
Sharrock WW, Suwanarusk R, Lek-Uthai U, Edstein MD, Kosaisavee V, Travers T, Jaidee A, Sriprawat K, Price RN, Nosten F, Russell B. Sharrock WW, et al. Among authors: nosten f. Malar J. 2008 May 27;7:94. doi: 10.1186/1475-2875-7-94. Malar J. 2008. PMID: 18505560 Free PMC article.
Chloroquine pharmacokinetics in pregnant and nonpregnant women with vivax malaria.
Lee SJ, McGready R, Fernandez C, Stepniewska K, Paw MK, Viladpai-nguen SJ, Thwai KL, Villegas L, Singhasivanon P, Greenwood BM, White NJ, Nosten F. Lee SJ, et al. Among authors: nosten f. Eur J Clin Pharmacol. 2008 Oct;64(10):987-92. doi: 10.1007/s00228-008-0500-z. Epub 2008 Jul 2. Eur J Clin Pharmacol. 2008. PMID: 18594802 Free article.
The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malaria.
Lee SJ, Stepniewska K, Anstey N, Ashley E, Barnes K, Binh TQ, D'Alessandro U, Day NP, de Vries PJ, Dorsey G, Guthmann JP, Mayxay M, Newton P, Nosten F, Olliaro P, Osario L, Pinoges L, Price R, Rowland M, Smithuis F, Taylor R, White NJ. Lee SJ, et al. Among authors: nosten f. Malar J. 2008 Aug 2;7:149. doi: 10.1186/1475-2875-7-149. Malar J. 2008. PMID: 18673575 Free PMC article.
Thrombocytopaenia in pregnant women with malaria on the Thai-Burmese border.
Tan SO, McGready R, Zwang J, Pimanpanarak M, Sriprawat K, Thwai KL, Moo Y, Ashley EA, Edwards B, Singhasivanon P, White NJ, Nosten F. Tan SO, et al. Among authors: nosten f. Malar J. 2008 Oct 15;7:209. doi: 10.1186/1475-2875-7-209. Malar J. 2008. PMID: 18922167 Free PMC article.
Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment.
Carrara VI, Zwang J, Ashley EA, Price RN, Stepniewska K, Barends M, Brockman A, Anderson T, McGready R, Phaiphun L, Proux S, van Vugt M, Hutagalung R, Lwin KM, Phyo AP, Preechapornkul P, Imwong M, Pukrittayakamee S, Singhasivanon P, White NJ, Nosten F. Carrara VI, et al. Among authors: nosten f. PLoS One. 2009;4(2):e4551. doi: 10.1371/journal.pone.0004551. Epub 2009 Feb 23. PLoS One. 2009. PMID: 19234601 Free PMC article.
Antimalarial therapies in children from Papua New Guinea.
Price RN, Dorsey G, Nosten F. Price RN, et al. Among authors: nosten f. N Engl J Med. 2009 Mar 19;360(12):1254; author reply 1255. doi: 10.1056/NEJMc090023. N Engl J Med. 2009. PMID: 19297580 Free article. No abstract available.
Population pharmacokinetics of lumefantrine in pregnant women treated with artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria.
Tarning J, McGready R, Lindegardh N, Ashley EA, Pimanpanarak M, Kamanikom B, Annerberg A, Day NP, Stepniewska K, Singhasivanon P, White NJ, Nosten F. Tarning J, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2009 Sep;53(9):3837-46. doi: 10.1128/AAC.00195-09. Epub 2009 Jun 29. Antimicrob Agents Chemother. 2009. PMID: 19564366 Free PMC article. Clinical Trial.
Artemisinin resistance in Plasmodium falciparum malaria.
Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, Tarning J, Lwin KM, Ariey F, Hanpithakpong W, Lee SJ, Ringwald P, Silamut K, Imwong M, Chotivanich K, Lim P, Herdman T, An SS, Yeung S, Singhasivanon P, Day NP, Lindegardh N, Socheat D, White NJ. Dondorp AM, et al. Among authors: nosten f. N Engl J Med. 2009 Jul 30;361(5):455-67. doi: 10.1056/NEJMoa0808859. N Engl J Med. 2009. PMID: 19641202 Free PMC article. Clinical Trial.
In vivo parasitological measures of artemisinin susceptibility.
Stepniewska K, Ashley E, Lee SJ, Anstey N, Barnes KI, Binh TQ, D'Alessandro U, Day NP, de Vries PJ, Dorsey G, Guthmann JP, Mayxay M, Newton PN, Olliaro P, Osorio L, Price RN, Rowland M, Smithuis F, Taylor WR, Nosten F, White NJ. Stepniewska K, et al. Among authors: nosten f. J Infect Dis. 2010 Feb 15;201(4):570-9. doi: 10.1086/650301. J Infect Dis. 2010. PMID: 20085495 Free PMC article.
A simple score to predict the outcome of severe malaria in adults.
Hanson J, Lee SJ, Mohanty S, Faiz MA, Anstey NM, Charunwatthana P, Yunus EB, Mishra SK, Tjitra E, Price RN, Rahman R, Nosten F, Htut Y, Hoque G, Hong Chau TT, Hoan Phu N, Hien TT, White NJ, Day NP, Dondorp AM. Hanson J, et al. Among authors: nosten f. Clin Infect Dis. 2010 Mar 1;50(5):679-85. doi: 10.1086/649928. Clin Infect Dis. 2010. PMID: 20105074 Free PMC article.
Two nonrecombining sympatric forms of the human malaria parasite Plasmodium ovale occur globally.
Sutherland CJ, Tanomsing N, Nolder D, Oguike M, Jennison C, Pukrittayakamee S, Dolecek C, Hien TT, do Rosário VE, Arez AP, Pinto J, Michon P, Escalante AA, Nosten F, Burke M, Lee R, Blaze M, Otto TD, Barnwell JW, Pain A, Williams J, White NJ, Day NP, Snounou G, Lockhart PJ, Chiodini PL, Imwong M, Polley SD. Sutherland CJ, et al. Among authors: nosten f. J Infect Dis. 2010 May 15;201(10):1544-50. doi: 10.1086/652240. J Infect Dis. 2010. PMID: 20380562
Malaria in children.
Crawley J, Chu C, Mtove G, Nosten F. Crawley J, et al. Among authors: nosten f. Lancet. 2010 Apr 24;375(9724):1468-81. doi: 10.1016/S0140-6736(10)60447-3. Lancet. 2010. PMID: 20417858
Exploring the contribution of candidate genes to artemisinin resistance in Plasmodium falciparum.
Imwong M, Dondorp AM, Nosten F, Yi P, Mungthin M, Hanchana S, Das D, Phyo AP, Lwin KM, Pukrittayakamee S, Lee SJ, Saisung S, Koecharoen K, Nguon C, Day NP, Socheat D, White NJ. Imwong M, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2010 Jul;54(7):2886-92. doi: 10.1128/AAC.00032-10. Epub 2010 Apr 26. Antimicrob Agents Chemother. 2010. PMID: 20421395 Free PMC article.
Artemisinin combination therapy for vivax malaria.
Douglas NM, Anstey NM, Angus BJ, Nosten F, Price RN. Douglas NM, et al. Among authors: nosten f. Lancet Infect Dis. 2010 Jun;10(6):405-16. doi: 10.1016/S1473-3099(10)70079-7. Lancet Infect Dis. 2010. PMID: 20510281 Free PMC article. Review.
Intrahost modeling of artemisinin resistance in Plasmodium falciparum.
Saralamba S, Pan-Ngum W, Maude RJ, Lee SJ, Tarning J, Lindegårdh N, Chotivanich K, Nosten F, Day NP, Socheat D, White NJ, Dondorp AM, White LJ. Saralamba S, et al. Among authors: nosten f. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):397-402. doi: 10.1073/pnas.1006113108. Epub 2010 Dec 20. Proc Natl Acad Sci U S A. 2011. PMID: 21173254 Free PMC article.
Methotrexate is highly potent against pyrimethamine-resistant Plasmodium vivax.
Imwong M, Russell B, Suwanarusk R, Nzila A, Leimanis ML, Sriprawat K, Kaewpongsri S, Phyo AP, Snounou G, Nosten F, Renia L. Imwong M, et al. Among authors: nosten f. J Infect Dis. 2011 Jan 15;203(2):207-10. doi: 10.1093/infdis/jiq024. Epub 2010 Dec 9. J Infect Dis. 2011. PMID: 21288820 Free PMC article.
Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay.
Campino S, Auburn S, Kivinen K, Zongo I, Ouedraogo JB, Mangano V, Djimde A, Doumbo OK, Kiara SM, Nzila A, Borrmann S, Marsh K, Michon P, Mueller I, Siba P, Jiang H, Su XZ, Amaratunga C, Socheat D, Fairhurst RM, Imwong M, Anderson T, Nosten F, White NJ, Gwilliam R, Deloukas P, MacInnis B, Newbold CI, Rockett K, Clark TG, Kwiatkowski DP. Campino S, et al. Among authors: nosten f. PLoS One. 2011;6(6):e20251. doi: 10.1371/journal.pone.0020251. Epub 2011 Jun 6. PLoS One. 2011. PMID: 21673999 Free PMC article.
A small amount of fat does not affect piperaquine exposure in patients with malaria.
Annerberg A, Lwin KM, Lindegardh N, Khrutsawadchai S, Ashley E, Day NP, Singhasivanon P, Tarning J, White NJ, Nosten F. Annerberg A, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2011 Sep;55(9):3971-6. doi: 10.1128/AAC.00279-11. Epub 2011 Jun 27. Antimicrob Agents Chemother. 2011. PMID: 21709087 Free PMC article. Clinical Trial.
Pharmacokinetics of amodiaquine and desethylamodiaquine in pregnant and postpartum women with Plasmodium vivax malaria.
Rijken MJ, McGready R, Jullien V, Tarning J, Lindegardh N, Phyo AP, Win AK, Hsi P, Cammas M, Singhasivanon P, White NJ, Nosten F. Rijken MJ, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2011 Sep;55(9):4338-42. doi: 10.1128/AAC.00154-11. Epub 2011 Jun 27. Antimicrob Agents Chemother. 2011. PMID: 21709098 Free PMC article. Clinical Trial.
A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax.
Russell B, Suwanarusk R, Borlon C, Costa FT, Chu CS, Rijken MJ, Sriprawat K, Warter L, Koh EG, Malleret B, Colin Y, Bertrand O, Adams JH, D'Alessandro U, Snounou G, Nosten F, Rénia L. Russell B, et al. Among authors: nosten f. Blood. 2011 Sep 29;118(13):e74-81. doi: 10.1182/blood-2011-04-348748. Epub 2011 Jul 18. Blood. 2011. PMID: 21768300 Free PMC article.
Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects.
McGready R, Phyo AP, Rijken MJ, Tarning J, Lindegardh N, Hanpithakpon W, Than HH, Hlaing N, Zin NT, Singhasivanon P, White NJ, Nosten F. McGready R, et al. Among authors: nosten f. Br J Clin Pharmacol. 2012 Mar;73(3):467-77. doi: 10.1111/j.1365-2125.2011.04103.x. Br J Clin Pharmacol. 2012. PMID: 21950338 Free PMC article.
Rectal pH in well and unwell infants.
Turner C, Aye Mya Thein N, Turner P, Nosten F, White NJ. Turner C, et al. Among authors: nosten f. J Trop Pediatr. 2012 Aug;58(4):311-3. doi: 10.1093/tropej/fmr088. Epub 2011 Oct 7. J Trop Pediatr. 2012. PMID: 21984527 Free PMC article.
Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria.
Lwin KM, Phyo AP, Tarning J, Hanpithakpong W, Ashley EA, Lee SJ, Cheah P, Singhasivanon P, White NJ, Lindegårdh N, Nosten F. Lwin KM, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2012 Mar;56(3):1571-7. doi: 10.1128/AAC.05877-11. Epub 2012 Jan 17. Antimicrob Agents Chemother. 2012. PMID: 22252804 Free PMC article. Clinical Trial.
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing.
Manske M, Miotto O, Campino S, Auburn S, Almagro-Garcia J, Maslen G, O'Brien J, Djimde A, Doumbo O, Zongo I, Ouedraogo JB, Michon P, Mueller I, Siba P, Nzila A, Borrmann S, Kiara SM, Marsh K, Jiang H, Su XZ, Amaratunga C, Fairhurst R, Socheat D, Nosten F, Imwong M, White NJ, Sanders M, Anastasi E, Alcock D, Drury E, Oyola S, Quail MA, Turner DJ, Ruano-Rubio V, Jyothi D, Amenga-Etego L, Hubbart C, Jeffreys A, Rowlands K, Sutherland C, Roper C, Mangano V, Modiano D, Tan JC, Ferdig MT, Amambua-Ngwa A, Conway DJ, Takala-Harrison S, Plowe CV, Rayner JC, Rockett KA, Clark TG, Newbold CI, Berriman M, MacInnis B, Kwiatkowski DP. Manske M, et al. Among authors: nosten f. Nature. 2012 Jul 19;487(7407):375-9. doi: 10.1038/nature11174. Nature. 2012. PMID: 22722859 Free PMC article.
Population pharmacokinetic and pharmacodynamic modeling of amodiaquine and desethylamodiaquine in women with Plasmodium vivax malaria during and after pregnancy.
Tarning J, Chotsiri P, Jullien V, Rijken MJ, Bergstrand M, Cammas M, McGready R, Singhasivanon P, Day NP, White NJ, Nosten F, Lindegardh N. Tarning J, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2012 Nov;56(11):5764-73. doi: 10.1128/AAC.01242-12. Epub 2012 Aug 27. Antimicrob Agents Chemother. 2012. PMID: 22926572 Free PMC article.
Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria.
Das D, Tripura R, Phyo AP, Lwin KM, Tarning J, Lee SJ, Hanpithakpong W, Stepniewska K, Menard D, Ringwald P, Silamut K, Imwong M, Chotivanich K, Yi P, Day NP, Lindegardh N, Socheat D, Nguon C, White NJ, Nosten F, Dondorp AM. Das D, et al. Among authors: nosten f. Clin Infect Dis. 2013 Mar;56(5):e48-58. doi: 10.1093/cid/cis958. Epub 2012 Nov 21. Clin Infect Dis. 2013. PMID: 23175556 Free PMC article. Clinical Trial.
Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia.
Takala-Harrison S, Clark TG, Jacob CG, Cummings MP, Miotto O, Dondorp AM, Fukuda MM, Nosten F, Noedl H, Imwong M, Bethell D, Se Y, Lon C, Tyner SD, Saunders DL, Socheat D, Ariey F, Phyo AP, Starzengruber P, Fuehrer HP, Swoboda P, Stepniewska K, Flegg J, Arze C, Cerqueira GC, Silva JC, Ricklefs SM, Porcella SF, Stephens RM, Adams M, Kenefic LJ, Campino S, Auburn S, MacInnis B, Kwiatkowski DP, Su XZ, White NJ, Ringwald P, Plowe CV. Takala-Harrison S, et al. Among authors: nosten f. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):240-5. doi: 10.1073/pnas.1211205110. Epub 2012 Dec 17. Proc Natl Acad Sci U S A. 2013. PMID: 23248304 Free PMC article.
Effective preparation of Plasmodium vivax field isolates for high-throughput whole genome sequencing.
Auburn S, Marfurt J, Maslen G, Campino S, Ruano Rubio V, Manske M, Machunter B, Kenangalem E, Noviyanti R, Trianty L, Sebayang B, Wirjanata G, Sriprawat K, Alcock D, Macinnis B, Miotto O, Clark TG, Russell B, Anstey NM, Nosten F, Kwiatkowski DP, Price RN. Auburn S, et al. Among authors: nosten f. PLoS One. 2013;8(1):e53160. doi: 10.1371/journal.pone.0053160. Epub 2013 Jan 4. PLoS One. 2013. PMID: 23308154 Free PMC article.
Malaria burden and artemisinin resistance in the mobile and migrant population on the Thai-Myanmar border, 1999-2011: an observational study.
Carrara VI, Lwin KM, Phyo AP, Ashley E, Wiladphaingern J, Sriprawat K, Rijken M, Boel M, McGready R, Proux S, Chu C, Singhasivanon P, White N, Nosten F. Carrara VI, et al. Among authors: nosten f. PLoS Med. 2013;10(3):e1001398. doi: 10.1371/journal.pmed.1001398. Epub 2013 Mar 5. PLoS Med. 2013. PMID: 23472056 Free PMC article.
High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool.
Woodrow CJ, Dahlström S, Cooksey R, Flegg JA, Le Nagard H, Mentré F, Murillo C, Ménard D, Nosten F, Sriprawat K, Musset L, Quashie NB, Lim P, Fairhurst RM, Nsobya SL, Sinou V, Noedl H, Pradines B, Johnson JD, Guerin PJ, Sibley CH, Le Bras J. Woodrow CJ, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2013 Jul;57(7):3121-30. doi: 10.1128/AAC.02350-12. Epub 2013 Apr 22. Antimicrob Agents Chemother. 2013. PMID: 23612201 Free PMC article.
Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia.
Miotto O, Almagro-Garcia J, Manske M, Macinnis B, Campino S, Rockett KA, Amaratunga C, Lim P, Suon S, Sreng S, Anderson JM, Duong S, Nguon C, Chuor CM, Saunders D, Se Y, Lon C, Fukuda MM, Amenga-Etego L, Hodgson AV, Asoala V, Imwong M, Takala-Harrison S, Nosten F, Su XZ, Ringwald P, Ariey F, Dolecek C, Hien TT, Boni MF, Thai CQ, Amambua-Ngwa A, Conway DJ, Djimdé AA, Doumbo OK, Zongo I, Ouedraogo JB, Alcock D, Drury E, Auburn S, Koch O, Sanders M, Hubbart C, Maslen G, Ruano-Rubio V, Jyothi D, Miles A, O'Brien J, Gamble C, Oyola SO, Rayner JC, Newbold CI, Berriman M, Spencer CC, McVean G, Day NP, White NJ, Bethell D, Dondorp AM, Plowe CV, Fairhurst RM, Kwiatkowski DP. Miotto O, et al. Among authors: nosten f. Nat Genet. 2013 Jun;45(6):648-55. doi: 10.1038/ng.2624. Epub 2013 Apr 28. Nat Genet. 2013. PMID: 23624527 Free PMC article.
Pharmacokinetic properties of artemether, dihydroartemisinin, lumefantrine, and quinine in pregnant women with uncomplicated plasmodium falciparum malaria in Uganda.
Tarning J, Kloprogge F, Dhorda M, Jullien V, Nosten F, White NJ, Guerin PJ, Piola P. Tarning J, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2013 Oct;57(10):5096-103. doi: 10.1128/AAC.00683-13. Epub 2013 Aug 5. Antimicrob Agents Chemother. 2013. PMID: 23917320 Free PMC article.
Neonatal intensive care in a Karen refugee camp: a 4 year descriptive study.
Turner C, Carrara V, Aye Mya Thein N, Chit Mo Mo Win N, Turner P, Bancone G, White NJ, McGready R, Nosten F. Turner C, et al. Among authors: nosten f. PLoS One. 2013 Aug 22;8(8):e72721. doi: 10.1371/journal.pone.0072721. eCollection 2013. PLoS One. 2013. PMID: 23991145 Free PMC article.
PlasmoView: a web-based resource to visualise global Plasmodium falciparum genomic variation.
Preston MD, Assefa SA, Ocholla H, Sutherland CJ, Borrmann S, Nzila A, Michon P, Hien TT, Bousema T, Drakeley CJ, Zongo I, Ouédraogo JB, Djimde AA, Doumbo OK, Nosten F, Fairhurst RM, Conway DJ, Roper C, Clark TG. Preston MD, et al. Among authors: nosten f. J Infect Dis. 2014 Jun 1;209(11):1808-15. doi: 10.1093/infdis/jit812. Epub 2013 Dec 12. J Infect Dis. 2014. PMID: 24338354 Free PMC article.
Single-dose radical cure of Plasmodium vivax: a step closer.
Price RN, Nosten F. Price RN, et al. Among authors: nosten f. Lancet. 2014 Mar 22;383(9922):1020-1. doi: 10.1016/S0140-6736(13)62672-0. Epub 2013 Dec 19. Lancet. 2014. PMID: 24360370 Free PMC article. No abstract available.
A morphometric and histological study of placental malaria shows significant changes to villous architecture in both Plasmodium falciparum and Plasmodium vivax infection.
Chaikitgosiyakul S, Rijken MJ, Muehlenbachs A, Lee SJ, Chaisri U, Viriyavejakul P, Turner GD, Pongponratn E, Nosten F, McGready R. Chaikitgosiyakul S, et al. Among authors: nosten f. Malar J. 2014 Jan 4;13:4. doi: 10.1186/1475-2875-13-4. Malar J. 2014. PMID: 24386908 Free PMC article.
Rapid clinical assessment to facilitate the triage of adults with falciparum malaria, a retrospective analysis.
Hanson J, Lee SJ, Mohanty S, Faiz MA, Anstey NM, Price RN, Charunwatthana P, Yunus EB, Mishra SK, Tjitra E, Rahman R, Nosten F, Htut Y, Maude RJ, Chau TT, Phu NH, Hien TT, White NJ, Day NP, Dondorp AM. Hanson J, et al. Among authors: nosten f. PLoS One. 2014 Jan 29;9(1):e87020. doi: 10.1371/journal.pone.0087020. eCollection 2014. PLoS One. 2014. PMID: 24489828 Free PMC article.
KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission.
Kuhen KL, Chatterjee AK, Rottmann M, Gagaring K, Borboa R, Buenviaje J, Chen Z, Francek C, Wu T, Nagle A, Barnes SW, Plouffe D, Lee MC, Fidock DA, Graumans W, van de Vegte-Bolmer M, van Gemert GJ, Wirjanata G, Sebayang B, Marfurt J, Russell B, Suwanarusk R, Price RN, Nosten F, Tungtaeng A, Gettayacamin M, Sattabongkot J, Taylor J, Walker JR, Tully D, Patra KP, Flannery EL, Vinetz JM, Renia L, Sauerwein RW, Winzeler EA, Glynne RJ, Diagana TT. Kuhen KL, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2014 Sep;58(9):5060-7. doi: 10.1128/AAC.02727-13. Epub 2014 Jun 9. Antimicrob Agents Chemother. 2014. PMID: 24913172 Free PMC article.
A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains.
Preston MD, Campino S, Assefa SA, Echeverry DF, Ocholla H, Amambua-Ngwa A, Stewart LB, Conway DJ, Borrmann S, Michon P, Zongo I, Ouédraogo JB, Djimde AA, Doumbo OK, Nosten F, Pain A, Bousema T, Drakeley CJ, Fairhurst RM, Sutherland CJ, Roper C, Clark TG. Preston MD, et al. Among authors: nosten f. Nat Commun. 2014 Jun 13;5:4052. doi: 10.1038/ncomms5052. Nat Commun. 2014. PMID: 24923250 Free PMC article.
Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates.
Ocholla H, Preston MD, Mipando M, Jensen AT, Campino S, MacInnis B, Alcock D, Terlouw A, Zongo I, Oudraogo JB, Djimde AA, Assefa S, Doumbo OK, Borrmann S, Nzila A, Marsh K, Fairhurst RM, Nosten F, Anderson TJ, Kwiatkowski DP, Craig A, Clark TG, Montgomery J. Ocholla H, et al. Among authors: nosten f. J Infect Dis. 2014 Dec 15;210(12):1991-2000. doi: 10.1093/infdis/jiu349. Epub 2014 Jun 19. J Infect Dis. 2014. PMID: 24948693 Free PMC article.
Spiroindolone KAE609 for falciparum and vivax malaria.
White NJ, Pukrittayakamee S, Phyo AP, Rueangweerayut R, Nosten F, Jittamala P, Jeeyapant A, Jain JP, Lefèvre G, Li R, Magnusson B, Diagana TT, Leong FJ. White NJ, et al. Among authors: nosten f. N Engl J Med. 2014 Jul 31;371(5):403-10. doi: 10.1056/NEJMoa1315860. N Engl J Med. 2014. PMID: 25075833 Free PMC article. Clinical Trial.
Spread of artemisinin resistance in Plasmodium falciparum malaria.
Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, Sreng S, Anderson JM, Mao S, Sam B, Sopha C, Chuor CM, Nguon C, Sovannaroth S, Pukrittayakamee S, Jittamala P, Chotivanich K, Chutasmit K, Suchatsoonthorn C, Runcharoen R, Hien TT, Thuy-Nhien NT, Thanh NV, Phu NH, Htut Y, Han KT, Aye KH, Mokuolu OA, Olaosebikan RR, Folaranmi OO, Mayxay M, Khanthavong M, Hongvanthong B, Newton PN, Onyamboko MA, Fanello CI, Tshefu AK, Mishra N, Valecha N, Phyo AP, Nosten F, Yi P, Tripura R, Borrmann S, Bashraheil M, Peshu J, Faiz MA, Ghose A, Hossain MA, Samad R, Rahman MR, Hasan MM, Islam A, Miotto O, Amato R, MacInnis B, Stalker J, Kwiatkowski DP, Bozdech Z, Jeeyapant A, Cheah PY, Sakulthaew T, Chalk J, Intharabut B, Silamut K, Lee SJ, Vihokhern B, Kunasol C, Imwong M, Tarning J, Taylor WJ, Yeung S, Woodrow CJ, Flegg JA, Das D, Smith J, Venkatesan M, Plowe CV, Stepniewska K, Guerin PJ, Dondorp AM, Day NP, White NJ; Tracking Resistance to Artemisinin Collaboration (TRAC). Ashley EA, et al. Among authors: nosten f. N Engl J Med. 2014 Jul 31;371(5):411-23. doi: 10.1056/NEJMoa1314981. N Engl J Med. 2014. PMID: 25075834 Free PMC article. Clinical Trial.
Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia.
Takala-Harrison S, Jacob CG, Arze C, Cummings MP, Silva JC, Dondorp AM, Fukuda MM, Hien TT, Mayxay M, Noedl H, Nosten F, Kyaw MP, Nhien NT, Imwong M, Bethell D, Se Y, Lon C, Tyner SD, Saunders DL, Ariey F, Mercereau-Puijalon O, Menard D, Newton PN, Khanthavong M, Hongvanthong B, Starzengruber P, Fuehrer HP, Swoboda P, Khan WA, Phyo AP, Nyunt MM, Nyunt MH, Brown TS, Adams M, Pepin CS, Bailey J, Tan JC, Ferdig MT, Clark TG, Miotto O, MacInnis B, Kwiatkowski DP, White NJ, Ringwald P, Plowe CV. Takala-Harrison S, et al. Among authors: nosten f. J Infect Dis. 2015 Mar 1;211(5):670-9. doi: 10.1093/infdis/jiu491. Epub 2014 Sep 1. J Infect Dis. 2015. PMID: 25180241 Free PMC article.
Pharmacokinetic interactions between primaquine and pyronaridine-artesunate in healthy adult Thai subjects.
Jittamala P, Pukrittayakamee S, Ashley EA, Nosten F, Hanboonkunupakarn B, Lee SJ, Thana P, Chairat K, Blessborn D, Panapipat S, White NJ, Day NP, Tarning J. Jittamala P, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2015 Jan;59(1):505-13. doi: 10.1128/AAC.03829-14. Epub 2014 Nov 10. Antimicrob Agents Chemother. 2015. PMID: 25385096 Free PMC article. Clinical Trial.
Plasmodium vivax: restricted tropism and rapid remodeling of CD71-positive reticulocytes.
Malleret B, Li A, Zhang R, Tan KS, Suwanarusk R, Claser C, Cho JS, Koh EG, Chu CS, Pukrittayakamee S, Ng ML, Ginhoux F, Ng LG, Lim CT, Nosten F, Snounou G, Rénia L, Russell B. Malleret B, et al. Among authors: nosten f. Blood. 2015 Feb 19;125(8):1314-24. doi: 10.1182/blood-2014-08-596015. Epub 2014 Nov 20. Blood. 2015. PMID: 25414440 Free PMC article.
Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance.
Mok S, Ashley EA, Ferreira PE, Zhu L, Lin Z, Yeo T, Chotivanich K, Imwong M, Pukrittayakamee S, Dhorda M, Nguon C, Lim P, Amaratunga C, Suon S, Hien TT, Htut Y, Faiz MA, Onyamboko MA, Mayxay M, Newton PN, Tripura R, Woodrow CJ, Miotto O, Kwiatkowski DP, Nosten F, Day NP, Preiser PR, White NJ, Dondorp AM, Fairhurst RM, Bozdech Z. Mok S, et al. Among authors: nosten f. Science. 2015 Jan 23;347(6220):431-5. doi: 10.1126/science.1260403. Epub 2014 Dec 11. Science. 2015. PMID: 25502316 Free PMC article.
Genetic architecture of artemisinin-resistant Plasmodium falciparum.
Miotto O, Amato R, Ashley EA, MacInnis B, Almagro-Garcia J, Amaratunga C, Lim P, Mead D, Oyola SO, Dhorda M, Imwong M, Woodrow C, Manske M, Stalker J, Drury E, Campino S, Amenga-Etego L, Thanh TN, Tran HT, Ringwald P, Bethell D, Nosten F, Phyo AP, Pukrittayakamee S, Chotivanich K, Chuor CM, Nguon C, Suon S, Sreng S, Newton PN, Mayxay M, Khanthavong M, Hongvanthong B, Htut Y, Han KT, Kyaw MP, Faiz MA, Fanello CI, Onyamboko M, Mokuolu OA, Jacob CG, Takala-Harrison S, Plowe CV, Day NP, Dondorp AM, Spencer CC, McVean G, Fairhurst RM, White NJ, Kwiatkowski DP. Miotto O, et al. Among authors: nosten f. Nat Genet. 2015 Mar;47(3):226-34. doi: 10.1038/ng.3189. Epub 2015 Jan 19. Nat Genet. 2015. PMID: 25599401 Free PMC article. Clinical Trial.
Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker.
Tun KM, Imwong M, Lwin KM, Win AA, Hlaing TM, Hlaing T, Lin K, Kyaw MP, Plewes K, Faiz MA, Dhorda M, Cheah PY, Pukrittayakamee S, Ashley EA, Anderson TJ, Nair S, McDew-White M, Flegg JA, Grist EP, Guerin P, Maude RJ, Smithuis F, Dondorp AM, Day NP, Nosten F, White NJ, Woodrow CJ. Tun KM, et al. Among authors: nosten f. Lancet Infect Dis. 2015 Apr;15(4):415-21. doi: 10.1016/S1473-3099(15)70032-0. Epub 2015 Feb 20. Lancet Infect Dis. 2015. PMID: 25704894 Free PMC article.
Defining the in vivo phenotype of artemisinin-resistant falciparum malaria: a modelling approach.
White LJ, Flegg JA, Phyo AP, Wiladpai-ngern JH, Bethell D, Plowe C, Anderson T, Nkhoma S, Nair S, Tripura R, Stepniewska K, Pan-Ngum W, Silamut K, Cooper BS, Lubell Y, Ashley EA, Nguon C, Nosten F, White NJ, Dondorp AM. White LJ, et al. Among authors: nosten f. PLoS Med. 2015 Apr 28;12(4):e1001823. doi: 10.1371/journal.pmed.1001823. eCollection 2015 Apr. PLoS Med. 2015. PMID: 25919029 Free PMC article.
Global extent of chloroquine-resistant Plasmodium vivax - Authors' reply.
Price RN, von Seidlein L, Valecha N, Nosten F, Baird JK, White NJ. Price RN, et al. Among authors: nosten f. Lancet Infect Dis. 2015 Jun;15(6):630-1. doi: 10.1016/S1473-3099(15)00018-3. Epub 2015 May 17. Lancet Infect Dis. 2015. PMID: 26008832 Free PMC article. No abstract available.
Lumefantrine and Desbutyl-Lumefantrine Population Pharmacokinetic-Pharmacodynamic Relationships in Pregnant Women with Uncomplicated Plasmodium falciparum Malaria on the Thailand-Myanmar Border.
Kloprogge F, McGready R, Hanpithakpong W, Blessborn D, Day NP, White NJ, Nosten F, Tarning J. Kloprogge F, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2015 Oct;59(10):6375-84. doi: 10.1128/AAC.00267-15. Epub 2015 Aug 3. Antimicrob Agents Chemother. 2015. PMID: 26239986 Free PMC article. Clinical Trial.
Comparison between Flow Cytometry, Microscopy, and Lactate Dehydrogenase-Based Enzyme-Linked Immunosorbent Assay for Plasmodium falciparum Drug Susceptibility Testing under Field Conditions.
Woodrow CJ, Wangsing C, Sriprawat K, Christensen PR, Nosten F, Rénia L, Russell B, Malleret B. Woodrow CJ, et al. Among authors: nosten f. J Clin Microbiol. 2015 Oct;53(10):3296-303. doi: 10.1128/JCM.01226-15. Epub 2015 Aug 12. J Clin Microbiol. 2015. PMID: 26269616 Free PMC article.
Elimination of Plasmodium falciparum in an area of multi-drug resistance.
Lwin KM, Imwong M, Suangkanarat P, Jeeyapant A, Vihokhern B, Wongsaen K, Snounou G, Keereecharoen L, White NJ, Nosten F. Lwin KM, et al. Among authors: nosten f. Malar J. 2015 Aug 16;14:319. doi: 10.1186/s12936-015-0838-5. Malar J. 2015. PMID: 26275909 Free PMC article.
Artemisinin resistance in Myanmar--Authors' reply.
Imwong M, Tun KM, Hlaing TM, Grist EP, Guerin P, Smithuis F, Dondorp AM, Day NP, Nosten F, White N, Woodrow CJ. Imwong M, et al. Among authors: nosten f. Lancet Infect Dis. 2015 Sep;15(9):1002-1003. doi: 10.1016/S1473-3099(15)00248-0. Lancet Infect Dis. 2015. PMID: 26333325 No abstract available.
Absence of association between Plasmodium falciparum small sub-unit ribosomal RNA gene mutations and in vitro decreased susceptibility to doxycycline.
Gaillard T, Wurtz N, Houzé S, Sriprawat K, Wangsing C, Hubert V, Lebras J, Nosten F, Briolant S, Pradines B; French National Reference Centre for Imported Malaria Study Group. Gaillard T, et al. Among authors: nosten f. Malar J. 2015 Sep 17;14:348. doi: 10.1186/s12936-015-0878-x. Malar J. 2015. PMID: 26377329 Free PMC article.
The epidemiology of subclinical malaria infections in South-East Asia: findings from cross-sectional surveys in Thailand-Myanmar border areas, Cambodia, and Vietnam.
Imwong M, Nguyen TN, Tripura R, Peto TJ, Lee SJ, Lwin KM, Suangkanarat P, Jeeyapant A, Vihokhern B, Wongsaen K, Van Hue D, Dong le T, Nguyen TU, Lubell Y, von Seidlein L, Dhorda M, Promnarate C, Snounou G, Malleret B, Rénia L, Keereecharoen L, Singhasivanon P, Sirithiranont P, Chalk J, Nguon C, Hien TT, Day N, White NJ, Dondorp A, Nosten F. Imwong M, et al. Among authors: nosten f. Malar J. 2015 Sep 30;14:381. doi: 10.1186/s12936-015-0906-x. Malar J. 2015. PMID: 26424000 Free PMC article.
New insights into the Plasmodium vivax transcriptome using RNA-Seq.
Zhu L, Mok S, Imwong M, Jaidee A, Russell B, Nosten F, Day NP, White NJ, Preiser PR, Bozdech Z. Zhu L, et al. Among authors: nosten f. Sci Rep. 2016 Feb 9;6:20498. doi: 10.1038/srep20498. Sci Rep. 2016. PMID: 26858037 Free PMC article.
Genomic epidemiology of artemisinin resistant malaria.
MalariaGEN Plasmodium falciparum Community Project. MalariaGEN Plasmodium falciparum Community Project. Elife. 2016 Mar 4;5:e08714. doi: 10.7554/eLife.08714. Elife. 2016. PMID: 26943619 Free PMC article.
Single Low Dose Primaquine (0.25 mg/kg) Does Not Cause Clinically Significant Haemolysis in G6PD Deficient Subjects.
Bancone G, Chowwiwat N, Somsakchaicharoen R, Poodpanya L, Moo PK, Gornsawun G, Kajeechiwa L, Thwin MM, Rakthinthong S, Nosten S, Thinraow S, Nyo SN, Ling CL, Wiladphaingern J, Kiricharoen NL, Moore KA, White NJ, Nosten F. Bancone G, et al. Among authors: nosten f, nosten s. PLoS One. 2016 Mar 24;11(3):e0151898. doi: 10.1371/journal.pone.0151898. eCollection 2016. PLoS One. 2016. PMID: 27010542 Free PMC article. Clinical Trial.
Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai-Myanmar Border (2003-2013): The Role of Parasite Genetic Factors.
Phyo AP, Ashley EA, Anderson TJC, Bozdech Z, Carrara VI, Sriprawat K, Nair S, White MM, Dziekan J, Ling C, Proux S, Konghahong K, Jeeyapant A, Woodrow CJ, Imwong M, McGready R, Lwin KM, Day NPJ, White NJ, Nosten F. Phyo AP, et al. Among authors: nosten f. Clin Infect Dis. 2016 Sep 15;63(6):784-791. doi: 10.1093/cid/ciw388. Epub 2016 Jun 16. Clin Infect Dis. 2016. PMID: 27313266 Free PMC article.
Genomic analysis of local variation and recent evolution in Plasmodium vivax.
Pearson RD, Amato R, Auburn S, Miotto O, Almagro-Garcia J, Amaratunga C, Suon S, Mao S, Noviyanti R, Trimarsanto H, Marfurt J, Anstey NM, William T, Boni MF, Dolecek C, Hien TT, White NJ, Michon P, Siba P, Tavul L, Harrison G, Barry A, Mueller I, Ferreira MU, Karunaweera N, Randrianarivelojosia M, Gao Q, Hubbart C, Hart L, Jeffery B, Drury E, Mead D, Kekre M, Campino S, Manske M, Cornelius VJ, MacInnis B, Rockett KA, Miles A, Rayner JC, Fairhurst RM, Nosten F, Price RN, Kwiatkowski DP. Pearson RD, et al. Among authors: nosten f. Nat Genet. 2016 Aug;48(8):959-964. doi: 10.1038/ng.3599. Epub 2016 Jun 27. Nat Genet. 2016. PMID: 27348299 Free PMC article.
Genomic Analysis Reveals a Common Breakpoint in Amplifications of the Plasmodium vivax Multidrug Resistance 1 Locus in Thailand.
Auburn S, Serre D, Pearson RD, Amato R, Sriprawat K, To S, Handayuni I, Suwanarusk R, Russell B, Drury E, Stalker J, Miotto O, Kwiatkowski DP, Nosten F, Price RN. Auburn S, et al. Among authors: nosten f. J Infect Dis. 2016 Oct 15;214(8):1235-42. doi: 10.1093/infdis/jiw323. Epub 2016 Jul 24. J Infect Dis. 2016. PMID: 27456706 Free PMC article.
Reply to Meshnick and Hastings et al.
Phyo AP, Ashley EA, Anderson TJ, Carrara VI, Woodrow CJ, White NJ, Nosten F. Phyo AP, et al. Among authors: nosten f. Clin Infect Dis. 2016 Dec 1;63(11):1528-1529. doi: 10.1093/cid/ciw584. Epub 2016 Aug 23. Clin Infect Dis. 2016. PMID: 27553372 Free PMC article. No abstract available.
Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria.
White NJ, Duong TT, Uthaisin C, Nosten F, Phyo AP, Hanboonkunupakarn B, Pukrittayakamee S, Jittamala P, Chuthasmit K, Cheung MS, Feng Y, Li R, Magnusson B, Sultan M, Wieser D, Xun X, Zhao R, Diagana TT, Pertel P, Leong FJ. White NJ, et al. Among authors: nosten f. N Engl J Med. 2016 Sep 22;375(12):1152-60. doi: 10.1056/NEJMoa1602250. N Engl J Med. 2016. PMID: 27653565 Free PMC article. Clinical Trial.
Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia.
Grist EP, Flegg JA, Humphreys G, Mas IS, Anderson TJ, Ashley EA, Day NP, Dhorda M, Dondorp AM, Faiz MA, Gething PW, Hien TT, Hlaing TM, Imwong M, Kindermans JM, Maude RJ, Mayxay M, McDew-White M, Menard D, Nair S, Nosten F, Newton PN, Price RN, Pukrittayakamee S, Takala-Harrison S, Smithuis F, Nguyen NT, Tun KM, White NJ, Witkowski B, Woodrow CJ, Fairhurst RM, Sibley CH, Guerin PJ. Grist EP, et al. Among authors: nosten f. Int J Health Geogr. 2016 Oct 24;15(1):37. doi: 10.1186/s12942-016-0064-6. Int J Health Geogr. 2016. PMID: 27776514 Free PMC article.
Estimation of the In Vivo MIC of Cipargamin in Uncomplicated Plasmodium falciparum Malaria.
Hien TT, White NJ, Thuy-Nhien NT, Hoa NT, Thuan PD, Tarning J, Nosten F, Magnusson B, Jain JP, Hamed K. Hien TT, et al. Among authors: nosten f. Antimicrob Agents Chemother. 2017 Jan 24;61(2):e01940-16. doi: 10.1128/AAC.01940-16. Print 2017 Feb. Antimicrob Agents Chemother. 2017. PMID: 27872070 Free PMC article. Clinical Trial.
Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis.
Hoglund RM, Workman L, Edstein MD, Thanh NX, Quang NN, Zongo I, Ouedraogo JB, Borrmann S, Mwai L, Nsanzabana C, Price RN, Dahal P, Sambol NC, Parikh S, Nosten F, Ashley EA, Phyo AP, Lwin KM, McGready R, Day NP, Guerin PJ, White NJ, Barnes KI, Tarning J. Hoglund RM, et al. Among authors: nosten f. PLoS Med. 2017 Jan 10;14(1):e1002212. doi: 10.1371/journal.pmed.1002212. eCollection 2017 Jan. PLoS Med. 2017. PMID: 28072872 Free PMC article.
Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens.
Chu CS, Bancone G, Moore KA, Win HH, Thitipanawan N, Po C, Chowwiwat N, Raksapraidee R, Wilairisak P, Phyo AP, Keereecharoen L, Proux S, Charunwatthana P, Nosten F, White NJ. Chu CS, et al. Among authors: nosten f. PLoS Med. 2017 Feb 7;14(2):e1002224. doi: 10.1371/journal.pmed.1002224. eCollection 2017 Feb. PLoS Med. 2017. PMID: 28170391 Free PMC article. Clinical Trial.
Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort.
Ataide R, Ashley EA, Powell R, Chan JA, Malloy MJ, O'Flaherty K, Takashima E, Langer C, Tsuboi T, Dondorp AM, Day NP, Dhorda M, Fairhurst RM, Lim P, Amaratunga C, Pukrittayakamee S, Hien TT, Htut Y, Mayxay M, Faiz MA, Beeson JG, Nosten F, Simpson JA, White NJ, Fowkes FJ. Ataide R, et al. Among authors: nosten f. Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3515-3520. doi: 10.1073/pnas.1615875114. Epub 2017 Mar 13. Proc Natl Acad Sci U S A. 2017. PMID: 28289193 Free PMC article.
P. falciparum infection and maternofetal antibody transfer in malaria-endemic settings of varying transmission.
McLean ARD, Stanisic D, McGready R, Chotivanich K, Clapham C, Baiwog F, Pimanpanarak M, Siba P, Mueller I, King CL, Nosten F, Beeson JG, Rogerson S, Simpson JA, Fowkes FJI. McLean ARD, et al. Among authors: nosten f. PLoS One. 2017 Oct 13;12(10):e0186577. doi: 10.1371/journal.pone.0186577. eCollection 2017. PLoS One. 2017. PMID: 29028827 Free PMC article.
In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate.
Cravo P, Machado RB, Leite JA, Leda T, Suwanarusk R, Bittencourt N, Albrecht L, Judice C, Lopes SCP, Lacerda MVG, Ferreira MU, Soares IS, Goh YS, Bargieri DY, Nosten F, Russell B, Rénia L, Costa FTM. Cravo P, et al. Among authors: nosten f. Malar J. 2018 Jan 10;17(1):20. doi: 10.1186/s12936-017-2144-x. Malar J. 2018. PMID: 29316918 Free PMC article.
Primaquine Pharmacokinetics in Lactating Women and Breastfed Infant Exposures.
Gilder ME, Hanpithakphong W, Hoglund RM, Tarning J, Win HH, Hilda N, Chu CS, Bancone G, Carrara VI, Singhasivanon P, White NJ, Nosten F, McGready R. Gilder ME, et al. Among authors: nosten f. Clin Infect Dis. 2018 Sep 14;67(7):1000-1007. doi: 10.1093/cid/ciy235. Clin Infect Dis. 2018. PMID: 29590311 Free PMC article.
A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum.
Roth A, Maher SP, Conway AJ, Ubalee R, Chaumeau V, Andolina C, Kaba SA, Vantaux A, Bakowski MA, Thomson-Luque R, Adapa SR, Singh N, Barnes SJ, Cooper CA, Rouillier M, McNamara CW, Mikolajczak SA, Sather N, Witkowski B, Campo B, Kappe SHI, Lanar DE, Nosten F, Davidson S, Jiang RHY, Kyle DE, Adams JH. Roth A, et al. Among authors: nosten f. Nat Commun. 2018 May 9;9(1):1837. doi: 10.1038/s41467-018-04221-9. Nat Commun. 2018. PMID: 29743474 Free PMC article.
Comparison of the Cumulative Efficacy and Safety of Chloroquine, Artesunate, and Chloroquine-Primaquine in Plasmodium vivax Malaria.
Chu CS, Phyo AP, Lwin KM, Win HH, San T, Aung AA, Raksapraidee R, Carrara VI, Bancone G, Watson J, Moore KA, Wiladphaingern J, Proux S, Sriprawat K, Winterberg M, Cheah PY, Chue AL, Tarning J, Imwong M, Nosten F, White NJ. Chu CS, et al. Among authors: nosten f. Clin Infect Dis. 2018 Oct 30;67(10):1543-1549. doi: 10.1093/cid/ciy319. Clin Infect Dis. 2018. PMID: 29889239 Free PMC article. Clinical Trial.
Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis.
Kloprogge F, Workman L, Borrmann S, Tékété M, Lefèvre G, Hamed K, Piola P, Ursing J, Kofoed PE, Mårtensson A, Ngasala B, Björkman A, Ashton M, Friberg Hietala S, Aweeka F, Parikh S, Mwai L, Davis TME, Karunajeewa H, Salman S, Checchi F, Fogg C, Newton PN, Mayxay M, Deloron P, Faucher JF, Nosten F, Ashley EA, McGready R, van Vugt M, Proux S, Price RN, Karbwang J, Ezzet F, Bakshi R, Stepniewska K, White NJ, Guerin PJ, Barnes KI, Tarning J. Kloprogge F, et al. Among authors: nosten f. PLoS Med. 2018 Jun 12;15(6):e1002579. doi: 10.1371/journal.pmed.1002579. eCollection 2018 Jun. PLoS Med. 2018. PMID: 29894518 Free PMC article.
Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics.
Auburn S, Benavente ED, Miotto O, Pearson RD, Amato R, Grigg MJ, Barber BE, William T, Handayuni I, Marfurt J, Trimarsanto H, Noviyanti R, Sriprawat K, Nosten F, Campino S, Clark TG, Anstey NM, Kwiatkowski DP, Price RN. Auburn S, et al. Among authors: nosten f. Nat Commun. 2018 Jul 3;9(1):2585. doi: 10.1038/s41467-018-04965-4. Nat Commun. 2018. PMID: 29968722 Free PMC article.
The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis.
Commons RJ, Simpson JA, Thriemer K, Humphreys GS, Abreha T, Alemu SG, Añez A, Anstey NM, Awab GR, Baird JK, Barber BE, Borghini-Fuhrer I, Chu CS, D'Alessandro U, Dahal P, Daher A, de Vries PJ, Erhart A, Gomes MSM, Gonzalez-Ceron L, Grigg MJ, Heidari A, Hwang J, Kager PA, Ketema T, Khan WA, Lacerda MVG, Leslie T, Ley B, Lidia K, Monteiro WM, Nosten F, Pereira DB, Phan GT, Phyo AP, Rowland M, Saravu K, Sibley CH, Siqueira AM, Stepniewska K, Sutanto I, Taylor WRJ, Thwaites G, Tran BQ, Tran HT, Valecha N, Vieira JLF, Wangchuk S, William T, Woodrow CJ, Zuluaga-Idarraga L, Guerin PJ, White NJ, Price RN. Commons RJ, et al. Among authors: nosten f. Lancet Infect Dis. 2018 Sep;18(9):1025-1034. doi: 10.1016/S1473-3099(18)30348-7. Epub 2018 Jul 20. Lancet Infect Dis. 2018. PMID: 30033231 Free PMC article.
Evaluation of a Novel Quantitative Test for Glucose-6-Phosphate Dehydrogenase Deficiency: Bringing Quantitative Testing for Glucose-6-Phosphate Dehydrogenase Deficiency Closer to the Patient.
Pal S, Bansil P, Bancone G, Hrutkay S, Kahn M, Gornsawun G, Penpitchaporn P, Chu CS, Nosten F, Domingo GJ. Pal S, et al. Among authors: nosten f. Am J Trop Med Hyg. 2019 Jan;100(1):213-221. doi: 10.4269/ajtmh.18-0612. Am J Trop Med Hyg. 2019. PMID: 30350771 Free PMC article.
The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background.
Zhu L, Tripathi J, Rocamora FM, Miotto O, van der Pluijm R, Voss TS, Mok S, Kwiatkowski DP, Nosten F, Day NPJ, White NJ, Dondorp AM, Bozdech Z; Tracking Resistance to Artemisinin Collaboration I. Zhu L, et al. Among authors: nosten f. Nat Commun. 2018 Dec 4;9(1):5158. doi: 10.1038/s41467-018-07588-x. Nat Commun. 2018. PMID: 30514877 Free PMC article.
Genomic Analysis of Plasmodium vivax in Southern Ethiopia Reveals Selective Pressures in Multiple Parasite Mechanisms.
Auburn S, Getachew S, Pearson RD, Amato R, Miotto O, Trimarsanto H, Zhu SJ, Rumaseb A, Marfurt J, Noviyanti R, Grigg MJ, Barber B, William T, Goncalves SM, Drury E, Sriprawat K, Anstey NM, Nosten F, Petros B, Aseffa A, McVean G, Kwiatkowski DP, Price RN. Auburn S, et al. Among authors: nosten f. J Infect Dis. 2019 Oct 22;220(11):1738-1749. doi: 10.1093/infdis/jiz016. J Infect Dis. 2019. PMID: 30668735 Free PMC article.
The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial.
von Seidlein L, Peto TJ, Landier J, Nguyen TN, Tripura R, Phommasone K, Pongvongsa T, Lwin KM, Keereecharoen L, Kajeechiwa L, Thwin MM, Parker DM, Wiladphaingern J, Nosten S, Proux S, Corbel V, Tuong-Vy N, Phuc-Nhi TL, Son DH, Huong-Thu PN, Tuyen NTK, Tien NT, Dong LT, Hue DV, Quang HH, Nguon C, Davoeung C, Rekol H, Adhikari B, Henriques G, Phongmany P, Suangkanarat P, Jeeyapant A, Vihokhern B, van der Pluijm RW, Lubell Y, White LJ, Aguas R, Promnarate C, Sirithiranont P, Malleret B, Rénia L, Onsjö C, Chan XH, Chalk J, Miotto O, Patumrat K, Chotivanich K, Hanboonkunupakarn B, Jittmala P, Kaehler N, Cheah PY, Pell C, Dhorda M, Imwong M, Snounou G, Mukaka M, Peerawaranun P, Lee SJ, Simpson JA, Pukrittayakamee S, Singhasivanon P, Grobusch MP, Cobelens F, Smithuis F, Newton PN, Thwaites GE, Day NPJ, Mayxay M, Hien TT, Nosten FH, Dondorp AM, White NJ. von Seidlein L, et al. Among authors: nosten s, nosten fh. PLoS Med. 2019 Feb 15;16(2):e1002745. doi: 10.1371/journal.pmed.1002745. eCollection 2019 Feb. PLoS Med. 2019. PMID: 30768615 Free PMC article. Clinical Trial.
Community engagement, social context and coverage of mass anti-malarial administration: Comparative findings from multi-site research in the Greater Mekong sub-Region.
Pell CL, Adhikari B, Myo Thwin M, Kajeechiwa L, Nosten S, Nosten FH, Sahan KM, Smithuis FM, Nguyen TN, Hien TT, Tripura R, Peto TJ, Sanann N, Nguon C, Pongvongsa T, Phommasone K, Mayxay M, Mukaka M, Peerawaranun P, Kaehler N, Cheah PY, Day NPJ, White NJ, Dondorp AM, von Seidlein L. Pell CL, et al. PLoS One. 2019 Mar 25;14(3):e0214280. doi: 10.1371/journal.pone.0214280. eCollection 2019. PLoS One. 2019. PMID: 30908523 Free PMC article. Clinical Trial.
The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density.
Slater HC, Ross A, Felger I, Hofmann NE, Robinson L, Cook J, Gonçalves BP, Björkman A, Ouedraogo AL, Morris U, Msellem M, Koepfli C, Mueller I, Tadesse F, Gadisa E, Das S, Domingo G, Kapulu M, Midega J, Owusu-Agyei S, Nabet C, Piarroux R, Doumbo O, Doumbo SN, Koram K, Lucchi N, Udhayakumar V, Mosha J, Tiono A, Chandramohan D, Gosling R, Mwingira F, Sauerwein R, Paul R, Riley EM, White NJ, Nosten F, Imwong M, Bousema T, Drakeley C, Okell LC. Slater HC, et al. Among authors: nosten f. Nat Commun. 2019 Mar 29;10(1):1433. doi: 10.1038/s41467-019-09441-1. Nat Commun. 2019. PMID: 30926893 Free PMC article.
Maternal Hepatitis B Infection Burden, Comorbidity and Pregnancy Outcome in a Low-Income Population on the Myanmar-Thailand Border: A Retrospective Cohort Study.
Bierhoff M, Angkurawaranon C, Myat Min A, Gilder ME, Win Tun N, Keereevijitt A, Kyi Win A, Win E, Carrara VI, Brummaier T, Chu CS, Thielemans L, Sriprawat K, Hanboonkunupakarn B, Rijken M, Nosten F, van Vugt M, McGready R. Bierhoff M, et al. Among authors: nosten f. J Pregnancy. 2019 Feb 25;2019:8435019. doi: 10.1155/2019/8435019. eCollection 2019. J Pregnancy. 2019. PMID: 30931155 Free PMC article.
Chloroquine Versus Dihydroartemisinin-Piperaquine With Standard High-dose Primaquine Given Either for 7 Days or 14 Days in Plasmodium vivax Malaria.
Chu CS, Phyo AP, Turner C, Win HH, Poe NP, Yotyingaphiram W, Thinraow S, Wilairisak P, Raksapraidee R, Carrara VI, Paw MK, Wiladphaingern J, Proux S, Bancone G, Sriprawat K, Lee SJ, Jeeyapant A, Watson J, Tarning J, Imwong M, Nosten F, White NJ. Chu CS, et al. Among authors: nosten f. Clin Infect Dis. 2019 Apr 8;68(8):1311-1319. doi: 10.1093/cid/ciy735. Clin Infect Dis. 2019. PMID: 30952158 Free PMC article. Clinical Trial.
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