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2014 1
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2018 29
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2022 38
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2026 27

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Page 1
Analytic Bounds on GAMLSS Model Variability of Normative White Matter Brain Charts.
Kim ME, Rudravaram G, Saunders A, Gao C, Ramadass K, Newlin NR, Kanakaraj P, Bogdanov S, Archer D, Hohman TJ, Jefferson AL, Morgan VL, Roche A, Englot DJ, Resnick SM, Beason Held LL, Bilgel M, Cutting LE, Barquero LA, D'Archangel MA, Nguyen TQ, Humphreys KL, Niu Y, Vinci-Booher S, Cascio CJ, Pechman KR, Shashikumar N; HABS-HD Study Team; Alzheimer’s Disease Neuroimaging Initiative; BIOCARD Study Team; Li Z, Vandekar SN, Zhang P, Gore JC, Liu Y, Zuo L, Schilling KG, Moyer DC, Landman BA. Kim ME, et al. bioRxiv [Preprint]. 2026 Feb 1:2026.01.28.702453. doi: 10.64898/2026.01.28.702453. bioRxiv. 2026. PMID: 41659596 Free PMC article. Preprint.
Revising the ABIDE MCI to dementia prediction model for automated cerebrospinal fluid assays.
van der Veere PJ, van Harten AC, van Maurik IS, Teunissen CE, Barkhof F, Vos SJB, Froelich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Frisoni GB, Spiru L, Freund-Levi Y, Wallin ÅK, Hampel H, Tsolaki M, Kłoszewska I, Mecocci P, Vellas B, Lovestone S, Galluzzi S, Herukka SK, Santana I, Baldeiras I, de Mendonca A, Silva D, Chetelat G, Poisnel G, Visser PJ, Johnson SC, Stormrud E, Hansson O, Palmqvist S, Piñol-Ripoll G; Alzheimer's Disease Neuroimaging Initiative; Berkhof J, van der Flier WM. van der Veere PJ, et al. Alzheimers Dement. 2026 Feb;22(2):e71192. doi: 10.1002/alz.71192. Alzheimers Dement. 2026. PMID: 41657128 Free PMC article.
Evaluating the association of apolipoprotein E genotype and cognitive resilience in SuperAgers.
Durant A, Mukherjee S, Lee ML, Choi SE, Scollard P, Klinedinst BS, Trittschuh EH, Mez J, Farrer LA, Gifford KA, Cruchaga C, Hassenstab J, Naj AC, Wang LS, Johnson SC, Engelman CD, Kukull WA, Keene CD, Saykin AJ, Cuccaro ML, Kunkle BW, Pericak-Vance MA, Martin ER, Bennett DA, Barnes LL, Schneider JA, Bush WS, Haines JL, Mayeux R, Vardarajan BN, Albert MS, Thompson PM, Jefferson AL; Alzheimer's Disease Neuroimaging Initiative (ADNI)*Alzheimer's Disease Genetics Consortium (ADGC)The Alzheimer's Disease Sequencing Project (ADSP); Crane PK, Dumitrescu L, Archer DB, Hohman TJ, Gaynor LS. Durant A, et al. Alzheimers Dement. 2026 Jan;22(1):e71024. doi: 10.1002/alz.71024. Alzheimers Dement. 2026. PMID: 41542929 Free PMC article.
Testing the effects of a text message intervention on depression and distress among Latino dementia caregivers: A randomized controlled trial protocol.
Perales-Puchalt J, Ramírez-Mantilla M, Moore HP, Velez-Uribe I, Sepulveda-Rivera V, Ruiz R, Fracachán-Cabrera M, Herrera Y, Baker C, Miras-Neira A, Bothwell B, Anderson H, Lewandowski T, Diaz FJ, Greiner KA, Williams K, Vidoni ED, Ellerbeck E, Burns JM. Perales-Puchalt J, et al. Contemp Clin Trials. 2026 Feb;161:108214. doi: 10.1016/j.cct.2025.108214. Epub 2026 Jan 2. Contemp Clin Trials. 2026. PMID: 41485525 Free PMC article.
A blood based mitochondrial functional index biomarker for Alzheimer's disease.
Hauger BM, Kemna RE, Kueck PJ, Strope TA, John CS, Smith KP, Mayfield HD, Herrold E, Cox KL, Bothwell R, Bantis L, Swerdlow RH, Morris JK, Wilkins HM. Hauger BM, et al. Alzheimers Dement. 2025 Dec;21(12):e71061. doi: 10.1002/alz.71061. Alzheimers Dement. 2025. PMID: 41457046 Free PMC article.
Structural similarity networks reveal brain vulnerability in dementia.
Montagnese M, Ebneabbasi A, García-San-Martín N, Pecci-Terroba C, Romero-García R, Morgan SE, Cole JH, Seidlitz J, Rittman T, Bethlehem RAI. Montagnese M, et al. Alzheimers Dement. 2025 Dec;21(12):e70973. doi: 10.1002/alz.70973. Alzheimers Dement. 2025. PMID: 41451870 Free PMC article.
Mapping the circulating proteome across neurodegeneration: A harmonized, consortium-scale framework for uncovering molecular pathophysiology.
Finney CA, An L, Winchester LM, Vogel J, Wilkins HM, Burns JM, Swerdlow RH, Slawson C, Rothstein JD; Global Neurodegeneration Proteomics Consortium (GNPC); Lutz MW, Saloner R, Shvetcov A. Finney CA, et al. bioRxiv [Preprint]. 2025 Dec 12:2025.12.09.693329. doi: 10.64898/2025.12.09.693329. bioRxiv. 2025. PMID: 41427267 Free PMC article. Preprint.
Longitudinal assessment of cognitive decline and resilience in high-level Alzheimer disease neuropathologic change.
Richardson TE, Kandoi S, Almeida FC, Rohde SK, Marx GA, Canbeldek L, Hiya S, Maldonado-Díaz C, Samanamud J, Clare K, Slocum CC, Kulumani Mahadevan LS, Chiu LY, Farrell K, Crary JF, Daoud EV, White CL 3rd, Espinoza SE, Gonzales MM, Oliveira TG, Walker JM. Richardson TE, et al. Alzheimers Res Ther. 2025 Dec 3;17(1):257. doi: 10.1186/s13195-025-01904-6. Alzheimers Res Ther. 2025. PMID: 41339920 Free PMC article.
Prognostic performance across Alzheimer's biomarkers, multi-modal physiological measures, and clinical history in asymptomatic individuals.
Ellis RJ, Airaud A, Jasodanand VH, Kowshik SS, Bellitti M, Kolachalama VB, Estiri H, Glymour MM, Dufouil C, Sperling RA, Bennett DA, Patel CJ; Alzheimer’s Disease Neuroimaging Initiative; Australian Imaging Biomarkers and Lifestyle flagship study of ageing. Ellis RJ, et al. medRxiv [Preprint]. 2025 Nov 20:2025.11.19.25340533. doi: 10.1101/2025.11.19.25340533. medRxiv. 2025. PMID: 41332865 Free PMC article. Preprint.
Bridging the Computational-Experimental Gap: Leveraging Large Language Model to Prioritize Alzheimer's Therapeutics Based on Comparison of Learning Models.
Li M, Niu S, Xu Y, Li J, Hu X, Liu D, Atik M, Xu X, Wang L, Ertekin-Taner N, Tao C. Li M, et al. Res Sq [Preprint]. 2025 Nov 7:rs.3.rs-7811754. doi: 10.21203/rs.3.rs-7811754/v1. Res Sq. 2025. Update in: Npj Health Syst. 2026;3(1):20. doi: 10.1038/s44401-026-00074-3. PMID: 41282120 Free PMC article. Updated. Preprint.
Lifespan Trajectories of Asymmetry in White Matter Tracts.
Kanakaraj P, Bogdanov S, Kim ME, Samir J, Gao C, Ramadass K, Rudravaram G, Newlin NR, Archer D, Hohman TJ, Jefferson AL, Morgan VL, Roche A, Englot DJ, Resnick SM, Held LLB, Cutting L, Barquero LA, D'Archangel MA, Nguyen TQ, Humphreys KL, Niu Y, Vinci-Booher S, Cascio CJ; HABS-HD Study Team; Alzheimer’s Disease Neuroimaging Initiative; BIOCARD Study Team; Li Z, Vandekar SN, Zhang P, Gore JC, Forkel SJ, Landman BA, Schilling KG. Kanakaraj P, et al. bioRxiv [Preprint]. 2025 Sep 29:2025.09.29.678806. doi: 10.1101/2025.09.29.678806. bioRxiv. 2025. PMID: 41256533 Free PMC article. Preprint.
A lightweight machine learning tool for Alzheimer's disease prediction.
Suresh V, Nahar T, Sharma A, Panchawagh S, Mohammed O, Muneer MA, Mishra D, Verma A, Sanker V, Mishra A, Malhotra HS, Garg RK. Suresh V, et al. Alzheimers Dement (Amst). 2025 Nov 17;17(4):e70187. doi: 10.1002/dad2.70187. eCollection 2025 Oct-Dec. Alzheimers Dement (Amst). 2025. PMID: 41256012 Free PMC article.
The tau biomarker cascade is condensed in Down syndrome compared to sporadic Alzheimer's disease.
Zammit MD, Bruzzone H, Cody KA, Morse J, Wilson R, Bettcher BT, McLachlan MJ, McVea AK, DiFilippo AH, Carey FJ, Janelidze S, Hansson O, Price JC, Laymon CM, Minhas DS, Luo W, Rosas HD, Lai F, Lee JH, Lao PJ, Ances BM, Krinsky-McHale SJ, Hom CL, Hartley SL, Zaman SH, Johnson SC, Cohen AD, Head E, Mapstone ME, Handen BL, Christian BT, Tudorascu DL, Langhough RE, Betthauser TJ; Alzheimer Biomarker Consortium–Down Syndrome. Zammit MD, et al. Brain. 2025 Nov 15:awaf428. doi: 10.1093/brain/awaf428. Online ahead of print. Brain. 2025. PMID: 41240365 Free PMC article.
The Neighborhoods Study: Examining the social exposome in Alzheimer's disease and related dementias.
George GC, Keller SA, Abner E, Adar S, Alosco ML, Apostolova LG, Bakulski K, Barnes LL, Bateman JR, Batterman S, Beach TG, Bendlin BB, Bennett DA, Betthauser TJ, Brewer J, Buckingham W, Carrión CI, Chodosh J, Craft S, Croff R, Fabio A, Farias ST, Feldman EL, Goldstein F, Goutman SA, Green-Harris G, Henderson V, Karikari TK, Kofler J, Kucharska-Newton A, Lamar M, Lanata S, Lepping RJ, Lingler J, Lockhart S, Mahnken J, Marsh K, Mathew J, Mecca AP, Meyer O, Miller B, Morris J, Neugroschl J, O'Connor MK, Paulson H, Perrin RJ, Pettigrew C, Pierce A, Powell WR, Pyarajan S, Raji CA, Reiman E, Risacher S, Rissman R, Espinosa PR, Sano M, Saykin AJ, Serrano GE, Singh V, Soldan A, Sultzer D, van Dyck CH, Whitmer R, Wisniewski T, Woltjer R, Yu M, Zhu CW, Kind AJH. George GC, et al. Alzheimers Dement. 2025 Nov;21(11):e70810. doi: 10.1002/alz.70810. Alzheimers Dement. 2025. PMID: 41230793 Free PMC article.
Generalizable MRI normative modelling to detect age-inappropriate neurodegeneration.
Parker TD, Bethlehem RAI, Seidlitz J, White SR, David MCB, Kolanko MA, Bernstock JD, Dorfschmidt L, Bourke N, Gailly de Taurines A, Hain JA, Del Giovane M, Graham NSN, Zimmerman KA, Losty EJF, Schöll M, Srikrishna M, Malhotra PA, Patel MC, Scott G, Alexander-Bloch AF, Bullmore ET, Sharp DJ; Alzheimer’s Disease Neuroimaging Initiative; Frontotemporal Lobar Degeneration Neuroimaging Initiative; Lifespan Brain Chart Consortium. Parker TD, et al. Alzheimers Res Ther. 2025 Nov 12;17(1):244. doi: 10.1186/s13195-025-01872-x. Alzheimers Res Ther. 2025. PMID: 41225656 Free PMC article.
Genome-wide association studies of TDP-43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B.
Godrich D, Pasteris J, Martin ER, Kunkle B, Naj AC, Hamilton K, Wang H, Lee WP, Dumitrescu L, Hohman TJ, Mayeux R, Larson EB, Crane PK, Keene CD, Latimer C, Mukherjee S, Kofler J, Kamboh MI, Bennett DA, Molina-Porcel L, Schellenberg G, Pericak-Vance MA, Cuccaro M, Scott WK, Rundek T, Kukull W, Montine T, Beecham GW; Alzheimer's Disease Genetics Consortium (ADGC). Godrich D, et al. Alzheimers Dement. 2025 Nov;21(11):e70760. doi: 10.1002/alz.70760. Alzheimers Dement. 2025. PMID: 41208712 Free PMC article.
The joint association of obesity and physical activity on cognitive function in Down syndrome.
Clina JG, Helsel BC, Hartley SL, Fleming-Batayneh VL, Handen B, Christian B, Head E, Mapstone M, Hom CL, Burns J, Ances B, Ptomey LT; Alzheimer Biomarker Consortium–Down Syndrome (ABC-DS) Investigators. Clina JG, et al. J Alzheimers Dis. 2025 Dec;108(3):1328-1338. doi: 10.1177/13872877251386474. Epub 2025 Oct 16. J Alzheimers Dis. 2025. PMID: 41100837 Free PMC article.
Primary age-related tauopathy.
Richardson TE, Walker JM, Farrell K, Oliveira TG, White CL 3rd, Crary JF. Richardson TE, et al. Acta Neuropathol. 2025 Oct 9;150(1):40. doi: 10.1007/s00401-025-02943-x. Acta Neuropathol. 2025. PMID: 41065841 Free PMC article. Review.
Validation of wellbeing scales among informal caregivers of Latinos with Alzheimer's disease and related dementias.
Perales-Puchalt J, Checa I, Espejo B, de la C Martín Carbonell M, Fracachán-Cabrera M, Baker C, Ramírez-Mantilla M, Mendez-Asaro P, Zimmer M, Williams K, Greiner KA, Zaudke J, Arreaza H, Velez-Uribe I, Moore HP, Sepulveda-Rivera V, Meyer K, Benton D, Kittle K, Gillen L, Burns JM. Perales-Puchalt J, et al. Hisp J Behav Sci. 2025 Feb;47(1):10.1177/07399863241308996. doi: 10.1177/07399863241308996. Epub 2025 Jan 10. Hisp J Behav Sci. 2025. PMID: 41049573 Free PMC article.
Testing the effects of a text message intervention on depression and distress among Latino dementia caregivers: a randomized controlled trial protocol.
Perales-Puchalt J, Ramírez-Mantilla M, Moore HP, Velez-Uribe I, Sepulveda-Rivera V, Ruiz R, Fracachán-Cabrera M, Herrera Y, Baker C, Miras-Neira A, Bothwell B, Anderson H, Lewandowski T, Diaz FJ, Greiner KA, Williams K, Vidoni ED, Ellerbeck E, Burns JM. Perales-Puchalt J, et al. medRxiv [Preprint]. 2025 Sep 18:2025.09.16.25335909. doi: 10.1101/2025.09.16.25335909. medRxiv. 2025. Update in: Contemp Clin Trials. 2026 Feb;161:108214. doi: 10.1016/j.cct.2025.108214. PMID: 41001476 Free PMC article. Updated. Preprint.
Cognitive trajectories among English- and Spanish-test-takers in the NACC.
Araujo-Menendez CEE, Carpio RA, Tarraf W, Lawrence AL, Lemus A, Membreno R, Chek CJW, Saelzler UG, Baena E, Morlett Paredes A, Stickel AM. Araujo-Menendez CEE, et al. Alzheimers Dement. 2025 Sep;21(9):e70721. doi: 10.1002/alz.70721. Alzheimers Dement. 2025. PMID: 40990058 Free PMC article.
Arterial stiffness moderates the link between NfL and cognition: The IGNITE study.
Norling AM, Lipsitz LA, Dufour AB, Travison TG, Sewell KR, Collins AM, Wan L, Grove G, Huang H, Oberlin LE, Jain S, Karikari TK, Morris JK, Jakicic JM, McAuley E, Kramer AF, Hillman CH, Vidoni ED, Billinger SA, Burns JM, Marsland AL, Kang C, Erickson KI. Norling AM, et al. Alzheimers Dement. 2025 Aug;21(8):e70554. doi: 10.1002/alz.70554. Alzheimers Dement. 2025. PMID: 40775489 Free PMC article. Clinical Trial.
Cognitive and neuropsychological trajectories in patients with mixed neurodegenerative pathologies.
Almeida FC, Marx GA, Rohde SK, Gonzales MM, Maldonado-Díaz C, Hiya S, Clare K, Samanamud J, Slocum CC, Kauffman J, Koenigsberg DG, Flores-Almazan V, Crary JF, Farrell K, White CL 3rd, Daoud EV, Walker JM, Oliveira TG, Richardson TE. Almeida FC, et al. Alzheimers Dement. 2025 Aug;21(8):e70575. doi: 10.1002/alz.70575. Alzheimers Dement. 2025. PMID: 40761006 Free PMC article.
Cross-tissue immune profiling of APOE ε4 reveals early dysregulation in Alzheimer's disease.
Finney C, Shvetcov A, Thomson S, Graham M, Hauger B, Keller J, Smoyer C, Tague S, Cho AN, Imam F, Krish V; Global Neurodegeneration Proteomics Consortium Global Neurodegeneration Proteomics Consortium; Taylor M, Mahnken J, Sullivan D, Reed J, Burns J, Slawson C, Swerdlow R, Wilkins H. Finney C, et al. Res Sq [Preprint]. 2025 Jul 15:rs.3.rs-7089423. doi: 10.21203/rs.3.rs-7089423/v1. Res Sq. 2025. PMID: 40709278 Free PMC article. Preprint.
Exploring potential mechanisms of an African protective locus for Alzheimer's disease in APOEε4 carriers.
Bertholim-Nasciben L, Nuytemans K, Van Booven D, Rajabli F, Moura S, Ramirez AM, Parker GS, Dykxhoorn DM, Wang L, Scott WK, Davis DA, Vontell RT, McInerney KF, Cuccaro ML, Byrd GS, Haines JL, Gearing M, Adams LD, Pericak-Vance MA, Young JI, Griswold AJ, Vance JM. Bertholim-Nasciben L, et al. Alzheimers Dement. 2025 Jul;21(7):e70500. doi: 10.1002/alz.70500. Alzheimers Dement. 2025. PMID: 40704449 Free PMC article.
Proteomic and metabolic profiling reveals APOE4-dependent shifts in whole brain, neuronal, and astrocytic mitochondrial function and glycolysis.
Lysaker CR, Johnson CN, Csikos V, Franczak E, Benson M, Gilmore CA, Birky CJ, Davis X, McCoin CS, Smith KP, Puchalska P, Crawford P, Slawson C, Thyfault JP, Geiger PC, Morris JK, Wilkins HM. Lysaker CR, et al. bioRxiv [Preprint]. 2025 Jun 16:2025.06.15.659811. doi: 10.1101/2025.06.15.659811. bioRxiv. 2025. PMID: 40666931 Free PMC article. Preprint.
APOE ε4 carriers share immune-related proteomic changes across neurodegenerative diseases.
Shvetcov A, Johnson ECB, Winchester LM, Walker KA, Wilkins HM, Thompson TG, Rothstein JD, Krish V, Imam FB; Global Neurodegeneration Proteomics Consortium (GNPC); Burns JM, Swerdlow RH, Slawson C, Finney CA. Shvetcov A, et al. Nat Med. 2025 Aug;31(8):2590-2601. doi: 10.1038/s41591-025-03835-z. Epub 2025 Jul 15. Nat Med. 2025. PMID: 40665049 Free PMC article.
The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging.
Imam F, Saloner R, Vogel JW, Krish V, Abdel-Azim G, Ali M, An L, Anastasi F, Bennett D, Pichet Binette A, Boxer AL, Bringmann M, Burns JM, Cruchaga C, Dage JL, Farinas A, Ferrucci L, Finney CA, Frasier M, Hansson O, Hohman TJ, Johnson ECB, Kivimaki M, Korologou-Linden R, Ruiz Laza A, Levey AI, Liepelt-Scarfone I, Lu L, Mattsson-Carlgren N, Middleton LT, Nho K, Oh HS, Petersen RC, Reiman EM, Robinson O, Rothstein JD, Saykin AJ, Shvetcov A, Slawson C, Smets B, Suárez-Calvet M, Tijms BM, Timmers M, Vieira F, Vilor-Tejedor N, Visser PJ, Walker KA, Winchester LM, Wyss-Coray T, Yang C, Bose N, Lovestone S; Global Neurodegeneration Proteomics Consortium (GNPC). Imam F, et al. Nat Med. 2025 Aug;31(8):2556-2566. doi: 10.1038/s41591-025-03834-0. Epub 2025 Jul 15. Nat Med. 2025. PMID: 40665048 Free PMC article.
White matter microstructure and macrostructure brain charts across the human lifespan.
Kim ME, Gao C, Ramadass K, Newlin NR, Kanakaraj P, Bogdanov S, Rudravaram G, Archer D, Hohman TJ, Jefferson AL, Morgan VL, Roche A, Englot DJ, Resnick SM, Beason Held LL, Cutting L, Barquero LA, D'archangel MA, Nguyen TQ, Humphreys KL, Niu Y, Vinci-Booher S, Cascio CJ; HABS-HD Study Team; Alzheimer’s Disease Neuroimaging Initiative; BIOCARD Study Team; Li Z, Vandekar SN, Zhang P, Gore JC, Landman BA, Schilling KG. Kim ME, et al. bioRxiv [Preprint]. 2025 May 9:2025.05.08.652953. doi: 10.1101/2025.05.08.652953. bioRxiv. 2025. PMID: 40654938 Free PMC article. Preprint.
Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline.
Wood Alexander M, Fischer DL, VandeVrede L, Nichols E, Yu L, Pike JR, Swardfager W, Wu CY, Masellis M, Galea LAM, Zukotynski K, Einstein G, Black SE, Barnes LL, Schneider JA, Arvanitakis Z, Casaletto KB, Rabin JS. Wood Alexander M, et al. Ann Neurol. 2025 Nov;98(5):1014-1026. doi: 10.1002/ana.27308. Epub 2025 Jul 11. Ann Neurol. 2025. PMID: 40646704 Free PMC article.
Structural Similarity Networks Reveal Brain Vulnerability in Dementia.
Montagnese M, Ebneabbasi A, García-San-Martín N, Pecci-Terroba C, Romero-García R, Morgan SE, Cole JH, Seidlitz J, Rittman T, Bethlehem RAI. Montagnese M, et al. medRxiv [Preprint]. 2025 Jun 11:2025.06.10.25328978. doi: 10.1101/2025.06.10.25328978. medRxiv. 2025. Update in: Alzheimers Dement. 2025 Dec;21(12):e70973. doi: 10.1002/alz.70973. PMID: 40585075 Free PMC article. Updated. Preprint.
Downward bias in the association between APOE and Alzheimer's Disease using prevalent and by-proxy disease sampling in the All of Us Research Program.
Mansel CO, Ghisays V, Mahnken JD, Swerdlow RH, Reiman EM, Karnes JH, Denny JC, Veatch OJ. Mansel CO, et al. medRxiv [Preprint]. 2025 May 23:2025.05.22.25328175. doi: 10.1101/2025.05.22.25328175. medRxiv. 2025. Update in: BMC Med Genomics. 2026 Apr 11. doi: 10.1186/s12920-026-02362-1. PMID: 40568661 Free PMC article. Updated. Preprint.
NIAGADS: A data repository for Alzheimer's disease and related dementia genomics.
Kuzma A, Valladares O, Greenfest-Allen E, Nicaretta H, Kirsch M, Ren Y, Katanic Z, White H, Wilk A, Bass L, Brettschneider J, Carter L, Cifello J, Chuang WH, Clark K, Gangadharan P, Haut J, Ho PC, Horng W, Iqbal T, Jin Y, Keskinen P, Rose AL, Moon MK, Manuel J, Qu L, Robbins F, Saravanan N, Sha J, Tate S, Zhao Y; Alzheimer's Disease Sequencing Project; Cantwell L, Gardner J, Chou SY, Tzeng JY, Bush W, Naj A, Kuksa P, Lee WP, Leung YY, Schellenberg G, Wang LS. Kuzma A, et al. Alzheimers Dement. 2025 Jun;21(6):e70255. doi: 10.1002/alz.70255. Alzheimers Dement. 2025. PMID: 40545618 Free PMC article.
Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity.
Moscoso A, Heeman F, Raghavan S, Costoya-Sánchez A, van Essen M, Mainta I, Camacho V, Rodríguez-Fonseca O, Silva-Rodríguez J, Perissinotti A, Gu Y, Yun J, Peretti D, Ribaldi F, Coomans EM, Brum WS, Grothe MJ, Aguiar P, Bischof GN, Drzezga A, Seo SW, Villeneuve S, Malpetti M, O'Brien JT, Rowe JB, van de Giessen EM, Ossenkoppele R, Jagust WJ, Smith R, Hansson O, Frisoni GB, Garibotto V, Soleimani-Meigooni DN, Carrillo M, Dickerson BC, La Joie R, Rabinovici GD, Apostolova LG, LaMontagne PJ, Pontecorvo MJ, Johnson KA, Sperling RA, Weiner MW, Petersen RC, Jack CR Jr, Vemuri P, Schöll M; PREVENT-AD Research Group, the Harvard Aging Brain Study, the LEADS Consortium, and the Alzheimer’s Disease Neuroimaging Initiative. Moscoso A, et al. JAMA. 2025 Jul 15;334(3):229-242. doi: 10.1001/jama.2025.7817. JAMA. 2025. PMID: 40522652 Free PMC article.
Sex-Specific Genetic Drivers of Memory, Executive Functioning, and Language Performance in Older Adults.
Eissman JM, Regelson AN, Walters S, Archer DB, Durant A, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez J, Kang M, Bush WS, Kunkle BW, Naj AC, Gifford KA, Bilgel M, Kuzma AB; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer’s Disease Genetics Consortium (ADGC); Alzheimer’s Disease Sequencing Project (ADSP); Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Vardarajan BN, Mayeux R, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Albert MS, Johnson SC, Engelman CD, Ferrucci L, Bennett DA, Barnes LL, Schneider JA, Resnick SM, Sperling RA, Crane PK, Hohman TJ, Dumitrescu L. Eissman JM, et al. medRxiv [Preprint]. 2025 Jun 2:2025.05.26.25328369. doi: 10.1101/2025.05.26.25328369. medRxiv. 2025. PMID: 40492063 Free PMC article. Preprint.
Alzheimer's Disease Sequencing Project release 4 whole genome sequencing dataset.
Leung YY, Lee WP, Kuzma AB, Nicaretta H, Valladares O, Gangadharan P, Qu L, Zhao Y, Ren Y, Cheng PL, Kuksa PP, Wang H, White H, Katanic Z, Bass L, Saravanan N, Greenfest-Allen E, Kirsch M, Cantwell L, Iqbal T, Wheeler NR, Farrell JJ, Zhu C, Turner SL, Gunasekaran TI, Mena PR, Jin Y, Carter L; Alzheimer's Disease Sequencing Project; Zhang X, Vardarajan BN, Toga A, Cuccaro M, Hohman TJ, Bush WS, Naj AC, Martin E, Dalgard CL, Kunkle BW, Farrer LA, Mayeux RP, Haines JL, Pericak-Vance MA, Schellenberg GD, Wang LS. Leung YY, et al. Alzheimers Dement. 2025 May;21(5):e70237. doi: 10.1002/alz.70237. Alzheimers Dement. 2025. PMID: 40407102 Free PMC article.
Age Alters Integrated Cerebrovascular and Cardiovascular Dynamic Responses to Exercise: Insights from a Systems Modeling Approach.
Billinger SA, Vidoni ED, Motwani K, Bartsch BL, Baldridge T, Walker M, Shojaie A. Billinger SA, et al. medRxiv [Preprint]. 2025 May 6:2025.05.02.25326897. doi: 10.1101/2025.05.02.25326897. medRxiv. 2025. Update in: J Appl Physiol (1985). 2025 Dec 1;139(6):1447-1461. doi: 10.1152/japplphysiol.00393.2025. PMID: 40385414 Free PMC article. Updated. Preprint.
A polygenetic rat model of divergent aerobic capacity reveals a liver-brain interaction impacting Alzheimer's disease-like phenotypes.
Lysaker CR, Kugler BA, Csikos V, Birky CJ, Gilmore CA, Wenger M, Franczak E, Davis X, Hauger BM, Allen JA, Troutwine BR, Gonzalez-Duran L, McCoin CS, Chauhan M, Harris JL, Frazier AL, Winter MK, Koch LG, Britton SL, Thyfault JP, Wilkins HM. Lysaker CR, et al. J Physiol. 2026 Mar;604(6):2542-2570. doi: 10.1113/JP286750. Epub 2025 May 11. J Physiol. 2026. PMID: 40349321
Long-Term Recall of Amyloid PET Results.
Scanlan M, Heigert H, Townley RA, Almahgraby A, Key MN, Morris JK, Burns JM, Vidoni ED. Scanlan M, et al. medRxiv [Preprint]. 2025 Apr 14:2025.04.10.25325602. doi: 10.1101/2025.04.10.25325602. medRxiv. 2025. PMID: 40321242 Free PMC article. Preprint.
LATE-NC Stage 3: a diagnostic rubric to differentiate severe LATE-NC from FTLD-TDP.
Shahidehpour RK, Katsumata Y, Dickson DW, Ghayal NB, Aung KZ, Wu X, Phe P, Jicha GA, Neltner AM, Archer JRC, Corrada MM, Kawas CH, Ahmad Sajjadi S, Woodworth DC, Bukhari SA, Montine TJ, Fardo DW, Nelson PT. Shahidehpour RK, et al. Acta Neuropathol. 2025 Apr 28;149(1):38. doi: 10.1007/s00401-025-02876-5. Acta Neuropathol. 2025. PMID: 40293530 Free PMC article.
Scaling Alzheimer's Care: The Case for Specialized Treatment Clinics.
Vidoni ED, Parks AC, Brunette A, Kreszyn K, Townley RA, Arthur AK, Gillen L, Puchalt JP, Lewandowski T, Mudaranthakam DP, Morris JK, Smith TR, Woodward J, Burns JM. Vidoni ED, et al. J Am Geriatr Soc. 2025 Aug;73(8):2545-2552. doi: 10.1111/jgs.19461. Epub 2025 Apr 7. J Am Geriatr Soc. 2025. PMID: 40192212 Free PMC article.
The striatum is an early, accurate indicator of amyloid burden using [11C]PiB in Down syndrome: Comparison of two radiotracers.
McLachlan M, Bettcher B, McVea A, DiFilippo A, Zammit M, LeMerise L, Rouanet J, Price J, Tudorascu D, Laymon C, Keator D, Lao P, Brickman AM, Fryer T, Hartley S, Ances BM, Rosas HD, Johnson S, Betthauser T, Stone CK, Zaman S, Handen B, Head E, Mapstone M, Christian BT, Investigators AD. McLachlan M, et al. Alzheimers Dement. 2025 Apr;21(4):e70141. doi: 10.1002/alz.70141. Alzheimers Dement. 2025. PMID: 40189783 Free PMC article.
Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer's disease.
Phillips JM, Dumitrescu LC, Archer DB, Regelson AN, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Kukull WA, Biber S, Mez J, Mahoney ER, Clifton M, Libby JB, Walters S, Bush WS, Engelman CD, Lu Q, Fardo DW, Widaman KF, Buckley RF, Mormino EC, Sanders RE, Clark LR, Gifford KA, Vardarajan B, Cuccaro ML, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Haines JL, Jefferson AL, Johnson SC, Albert MS, Keene CD, Saykin AJ, Risacher SL, Larson EB, Sperling RA, Mayeux R, Goate AM, Renton AE, Marcora E, Fulton-Howard B, Patel T, Bennett DA, Schneider JA, Barnes LL, Cruchaga C, Hassenstab J, Belloy ME, Andrews SJ, Resnick SM, Bilgel M, An Y, Beason-Held LL, Walker KA, Duggan MR, Klinedinst BS, Crane PK, Hohman TJ. Phillips JM, et al. Brain. 2025 Aug 1;148(8):2714-2729. doi: 10.1093/brain/awaf106. Brain. 2025. PMID: 40111762 Free PMC article.
Blood biomarkers differentiate AD-related versus non-AD-related cognitive deficits.
Sewell KR, Oberlin LE, Karikari TK, Olvera-Rojas M, Wan L, Morris JK, Kueck PJ, Zeng X, Huang H, Grove G, Chen Y, Lafferty TK, Sehrawat A, Kamboh MI, Marsland AL, Kramer AF, McAuley E, Burns JM, Hillman CH, Vidoni ED, Kang C, Erickson KI. Sewell KR, et al. Alzheimers Dement. 2025 Mar;21(3):e14619. doi: 10.1002/alz.14619. Alzheimers Dement. 2025. PMID: 40110626 Free PMC article.
Discussing the Interplay of Social Determinants of Health, Aging, and Alzheimer's Biomarkers in U.S. Latinos.
Martinez JE, Perales-Puchalt J, Rodriguez MJ, Rosselli M, Salazar C, Marquez DX, Lamar M, Vila-Castelar C, Rascovsky K, O'Bryant S, Vintimilla R, Díaz-Santos M, Velez Uribe I, Quiroz YT, Llibre-Guerra JJ; US Consortium of Aging, Dementia & Latino Studies (CADLAS). Martinez JE, et al. J Gerontol A Biol Sci Med Sci. 2025 Jul 24;80(8):glaf020. doi: 10.1093/gerona/glaf020. J Gerontol A Biol Sci Med Sci. 2025. PMID: 40052962 Free PMC article. Review.
Slowed Driving Reaction Time in Preclinical Alzheimer's Disease.
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The need for identifying neuropsychiatric symptoms and neural correlates among racially and ethnically minoritized older adults. Commentary on "Neuropsychiatric symptoms and white matter hyperintensities in older adults without dementia" by Liampas et al.
Rodriguez MJ, Perales-Puchalt J. Rodriguez MJ, et al. Int Psychogeriatr. 2025 Jan;37(1):100022. doi: 10.1016/j.inpsyc.2024.100022. Epub 2024 Dec 4. Int Psychogeriatr. 2025. PMID: 39924265 Free PMC article. No abstract available.
Evaluating the association of APOE genotype and cognitive resilience in SuperAgers.
Durant A, Mukherjee S, Lee ML, Choi SE, Scollard P, Klinedinst BS, Trittschuh EH, Mez J, Farrer LA, Gifford KA, Cruchaga C, Hassenstab J, Naj AC, Wang LS, Johnson SC, Engelman CD, Kukull WA, Keene CD, Saykin AJ, Cuccaro ML, Kunkle BW, Pericak-Vance MA, Martin ER, Bennett DA, Barnes LL, Schneider JA, Bush WS, Haines JL, Mayeux R, Vardarajan BN, Albert MS, Thompson PM, Jefferson AL; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer’s Disease Genetics Consortium (ADGC); Alzheimer’s Disease Sequencing Project (ADSP); Crane PK, Dumitrescu L, Archer DB, Hohman TJ, Gaynor LS. Durant A, et al. medRxiv [Preprint]. 2025 Jun 25:2025.01.07.25320117. doi: 10.1101/2025.01.07.25320117. medRxiv. 2025. Update in: Alzheimers Dement. 2026 Jan;22(1):e71024. doi: 10.1002/alz.71024. PMID: 39830268 Free PMC article. Updated. Preprint.
Stereo-seq of the prefrontal cortex in aging and Alzheimer's disease.
Gong Y, Haeri M, Zhang X, Li Y, Liu A, Wu D, Zhang Q, Jazwinski SM, Zhou X, Wang X, Zhang K, Jiang L, Chen YP, Yan X, Swerdlow RH, Shen H, Deng HW. Gong Y, et al. Nat Commun. 2025 Jan 8;16(1):482. doi: 10.1038/s41467-024-54715-y. Nat Commun. 2025. PMID: 39779708 Free PMC article.
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