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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 25
1988 2
1989 2
1991 2
1992 2
1993 1
1995 2
1997 8
1998 14
1999 19
2000 25
2001 25
2002 28
2003 45
2004 45
2005 55
2006 69
2007 74
2008 123
2009 206
2010 215
2011 245
2012 386
2013 755
2014 1019
2015 1723
2016 2514
2017 2076
2018 2577
2019 2752
2020 3188
2021 3316
2022 3148
2023 2994
2024 2589
2025 618

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26,490 results

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Page 1
Orthopaedic Implant-Associated Rhabdomyosarcoma.
Brown DE, Saoud C, Antonescu CR, Wexler LH, Bartlett EK, Morris CD. Brown DE, et al. J Am Acad Orthop Surg. 2025 May 9;33(12):655-662. doi: 10.5435/JAAOS-D-25-00160. J Am Acad Orthop Surg. 2025. PMID: 40479555
Inherited mitochondrial genetics as a predictor of immune checkpoint inhibition efficacy in melanoma.
Monson KR, Ferguson R, Handzlik JE, Morales L, Xiong J, Chat V, Dagayev S, Khodadadi-Jamayran A, Simpson D, Kazlow E, Bunis A, Sreenivasaiah C, Ibrahim M, Voloshyna I, Ouwerkerk W, Luiten RM, Capone M, Madonna G, Lu Y, Shao Y, Pavlick A, Krogsgaard M, Mehnert J, Tang H, Dolfi S, Tenney D, Haanen JBAG, Gajewski TF, Hodi FS, Flaherty KT, Couts K, Robinson W, Puzanov I, Ernstoff MS, Rahma O, Postow M, Sullivan RJ, Luke JJ, Ascierto PA; IO-GEM Consortium; Osman I, Kirchhoff T. Monson KR, et al. Nat Med. 2025 Jun 5. doi: 10.1038/s41591-025-03699-3. Online ahead of print. Nat Med. 2025. PMID: 40473950
Responsiveness of different MET tumour alterations to type I and type II MET inhibitors.
Murciano-Goroff YR, Foglizzo V, Chang J, Rekhtman N, Sisk AE, Gibson J, Judka L, Clemens K, Roa P, Ahmed SS, Bremer NV, Binaco CL, Muzungu SK, Rodriguez E, Merrill M, Sgroe E, Repetto M, Stadler ZK, Berger MF, Yu HA, Toska E, Kannan S, Verma CS, Drilon A, Cocco E. Murciano-Goroff YR, et al. Clin Transl Med. 2025 May;15(5):e70338. doi: 10.1002/ctm2.70338. Clin Transl Med. 2025. PMID: 40437874 Free PMC article.
WNK1 mediates M-CSF-induced macropinocytosis to enforce macrophage lineage fidelity.
Trzeciak AJ, Liu ZL, Gatie M, Krebs AS, Saitz Rojas W, O'Neal AJ, Baako AK, Wang Z, Nelson J, Miranda IC, Uddin J, Lipshutz A, Xie J, Huang CL, Saavedra PHV, Hadjantonakis AK, Overholtzer M, Glickman MS, Subramanya AR, Vierbuchen T, Etchegaray JI, Lucas CD, Parkhurst CN, Perry JSA. Trzeciak AJ, et al. Nat Commun. 2025 May 28;16(1):4945. doi: 10.1038/s41467-025-59901-0. Nat Commun. 2025. PMID: 40436823 Free PMC article.
Effect of bevacizumab on non-target intracranial meningiomas and non-vestibular schwannomas in NF2-related schwannomatosis: NF104.
Nakhate V, Ly I, Muzikansky A, Rapalino O, Allen JC, Blakeley JO, Campian JL, Clapp DW, Dhall G, Jain RK, Karajannis MA, Packer RJ, Tonsgard J, Ullrich NJ, Korf BR, Fisher MJ, Plotkin SR; Neurofibromatosis Clinical Trials Consortium. Nakhate V, et al. J Neurooncol. 2025 May 28. doi: 10.1007/s11060-025-05020-1. Online ahead of print. J Neurooncol. 2025. PMID: 40434540
FOXA2 promotes metastatic competence in small cell lung cancer.
Kawasaki K, Salehi S, Zhan YA, Chen K, Lee JH, Salataj E, Zhong H, Manoj P, Kinyua D, Mello BP, Sridhar H, Tischfield SE, Linkov I, Ceglia N, Zatzman M, Havasov E, Shah NJ, Meng F, Loomis B, Bhanot UK, Redin E, de Stanchina E, Hamard PJ, Koche RP, McPherson A, Quintanal-Villalonga Á, Shah SP, Massagué J, Rudin CM. Kawasaki K, et al. Nat Commun. 2025 May 26;16(1):4865. doi: 10.1038/s41467-025-60141-5. Nat Commun. 2025. PMID: 40419484 Free PMC article.
At-RS31 orchestrates hierarchical cross-regulation of splicing factors and integrates alternative splicing with TOR-ABA pathways.
Köster T, Venhuizen P, Lewinski M, Petrillo E, Marquez Y, Fuchs A, Ray D, Nimeth BA, Riegler S, Franzmeier S, Rodríguez FS, Aballay FE, Tognacca RS, Zheng H, Hughes T, Morris Q, Barta A, Staiger D, Kalyna M. Köster T, et al. New Phytol. 2025 May 26. doi: 10.1111/nph.70221. Online ahead of print. New Phytol. 2025. PMID: 40415535
APOBEC3 mutagenesis drives therapy resistance in breast cancer.
Gupta A, Gazzo A, Selenica P, Safonov A, Pareja F, da Silva EM, Brown DN, Shao H, Zhu Y, Patel J, Blanco-Heredia J, Stefanovska B, Carpenter MA, Chen Y, Vegas I, Pei X, Frosina D, Jungbluth AA, Ladanyi M, Curigliano G, Weigelt B, Riaz N, Powell SN, Razavi P, Harris RS, Reis-Filho JS, Marra A, Chandarlapaty S. Gupta A, et al. Nat Genet. 2025 May 16. doi: 10.1038/s41588-025-02187-1. Online ahead of print. Nat Genet. 2025. PMID: 40379787
Mutant IDH1 cooperates with NPM1c or FLT3ITD to drive distinct myeloid diseases and molecular outcomes.
Sakamoto T, Leca J, Zhang X, Meydan C, Foox J, Ramachandran P, Hendrikse LD, Zhou W, Berger T, Fortin J, Chan SM, Chiang MF, Inoue S, Li WY, Chu MF, Duncan GS, Wakeham A, Lemonnier F, Tobin C, Mcwilliam R, Colonna I, Bontoux C, Jafari SM, Bowman RL, Nicolay B, Ronseaux S, Narayanaswamy R, Levine RL, Melnick AM, Mason CE, Minden MD, Mak TW. Sakamoto T, et al. Proc Natl Acad Sci U S A. 2025 May 20;122(20):e2415779122. doi: 10.1073/pnas.2415779122. Epub 2025 May 16. Proc Natl Acad Sci U S A. 2025. PMID: 40377995
RNA transcripts serve as a template for double-strand break repair in human cells.
Jalan M, Brambati A, Shah H, McDermott N, Patel J, Zhu Y, Doymaz A, Wu J, Anderson KS, Gazzo A, Pareja F, Yamaguchi TN, Vougiouklakis T, Ahmed-Seghir S, Steinberg P, Neiman-Golden A, Azeroglu B, Gomez-Aguilar J, da Silva EM, Hussain S, Higginson D, Boutros PC, Riaz N, Reis-Filho JS, Powell SN, Sfeir A. Jalan M, et al. Nat Commun. 2025 May 10;16(1):4349. doi: 10.1038/s41467-025-59510-x. Nat Commun. 2025. PMID: 40348775 Free PMC article.
Consensus Recommendations for Hyperpolarized [1-13C]pyruvate MRI Multi-center Human Studies.
Punwani S, Larson PE, Laustsen C, VanderMeulen J, Ardenkjær-Larsen JH, Autry AW, Bankson JA, Bernard J, Bok R, Bertelsen LB, Che J, Chen AP, Chowdhury R, Comment A, Cunningham CH, Dang D, Gallagher FA, Gaunt A, Gong Y, Gordon JW, Grimmer A, Grist J, Hansen ESS, Lerche MH, Hesketh RL, Hoevener JB, Hsieh CY, Keshari KR, Kozerke S, Lanz T, Mayer D, McLean M, Park JM, Slater J, Tyler D, Vanderheyden JL, von Morze C, Zaccagna F, Zaha V, Xu D, Vigneron D; HP 13C MRI Consensus Group. Punwani S, et al. ArXiv [Preprint]. 2025 Apr 29:arXiv:2504.20440v1. ArXiv. 2025. PMID: 40342865 Free PMC article. Preprint.
Identifying baseline rectal MRI features as predictive indicators for local recurrence and metastatic disease in rectal cancer treated with surgical resection and neoadjuvant therapy or surgical resection alone.
El Homsi M, Javed-Tayyab S, Charbel C, Golia Pernicka JS, Paroder V, White C, Capanu M, Rodriguez L, Gangai N, Petkovska I. El Homsi M, et al. Eur J Radiol. 2025 Jul;188:112152. doi: 10.1016/j.ejrad.2025.112152. Epub 2025 May 1. Eur J Radiol. 2025. PMID: 40319786
Pathologic Response to Immunotherapy is Associated with Survival in Patients Undergoing Delayed Nephrectomy for Metastatic Renal Cell Carcinoma.
Khandwala YS, Reese SW, Ucpinar BA, Knezevic A, Eismann L, Wu CY, Mittal R, Doshi S, Barbakoff D, Sanmiguel AL, Coleman J, Dawidek M, Motzer RJ, Russo P, Akin O, Kotecha RR, Chen Y, Voss MH, Hakimi AA. Khandwala YS, et al. medRxiv [Preprint]. 2025 Apr 25:2025.04.24.25326353. doi: 10.1101/2025.04.24.25326353. medRxiv. 2025. PMID: 40313275 Free PMC article. Preprint.
Combined Portal and Hepatic Vein Embolization Produces Greater Hypertrophy than Portal Vein Embolization Alone with Similar Post-Hepatectomy Outcomes and is not Impacted by Hepatic Artery Infusion Chemotherapy.
Choubey AP, Chou JF, Soares KC, Wei AC, D'Angelica MI, Jarnagin WR, Gonen M, Balachandran VP, Drebin J, Santos E, Camacho JC, Kingham TP, Ridouani F. Choubey AP, et al. Ann Surg Oncol. 2025 Apr 30. doi: 10.1245/s10434-025-17287-9. Online ahead of print. Ann Surg Oncol. 2025. PMID: 40304945
Investigative needle core biopsies support multimodal deep-data generation in glioblastoma.
Yu KKH, Basu S, Baquer G, Ahn R, Gantchev J, Jindal S, Regan MS, Abou-Mrad Z, Prabhu MC, Williams MJ, D'Souza AD, Malinowski SW, Hopland K, Elhanati Y, Stopka SA, Stortchevoi A, Couturier C, He Z, Sun J, Chen Y, Espejo AB, Chow KH, Yerrum S, Kao PL, Kerrigan BP, Norberg L, Nielsen D; GBM TeamLab; Puduvalli VK, Huse J, Beroukhim R, Kim BYS, Goswami S, Boire A, Frisken S, Cima MJ, Holdhoff M, Lucas CG, Bettegowda C, Levine SS, Bale TA, Brennan C, Reardon DA, Lang FF, Chiocca EA, Ligon KL, White FM, Sharma P, Tabar V, Agar NYR. Yu KKH, et al. Nat Commun. 2025 Apr 28;16(1):3957. doi: 10.1038/s41467-025-58452-8. Nat Commun. 2025. PMID: 40295505 Free PMC article.
Sympathetic axonogenesis promotes adenoid cystic carcinoma progression.
Chen CH, Reva B, Katabi N, Wizel A, Xu H, Ho AL, Morris LGT, Bakst RL, Parikh AS, Drier Y, Deborde S, Wong RJ. Chen CH, et al. J Exp Med. 2025 Jul 7;222(7):e20242250. doi: 10.1084/jem.20242250. Epub 2025 Apr 24. J Exp Med. 2025. PMID: 40272482 Free article.
Patient-Reported Outcomes Program at Scale at a Cancer Center.
Polubriaginof FCG, Lipitz-Snyderman A, Chimonas S, Kuperman GJ, Stetson PD. Polubriaginof FCG, et al. JCO Clin Cancer Inform. 2025 Apr;9:e2400253. doi: 10.1200/CCI-24-00253. Epub 2025 Apr 22. JCO Clin Cancer Inform. 2025. PMID: 40262062
A Competency-Based Ultrasound-Guided Breast Biopsy Training Program for Radiologists From Low-and-Middle-Income Countries that Leverages Mobile Health Technology (NCT04501419): A Study Protocol.
Omisore AD, Egberongbe AA, Pace LE, Raza S, Akinola RA, Obajimi MO, Sevilimedu V, Bryce Y, Mango VL, Alatise OI, Kingham TP, Morris EA, Sutton EJ. Omisore AD, et al. Cancer Control. 2025 Jan-Dec;32:10732748251334435. doi: 10.1177/10732748251334435. Epub 2025 Apr 18. Cancer Control. 2025. PMID: 40250340 Free PMC article.
Factors Associated with Disease Progression after Discontinuation of Immune Checkpoint Inhibitors for Immune-Related Toxicity in Patients with Advanced Non-Small Cell Lung Cancer.
Pecci F, Thummalapalli R, Alden SL, Ricciuti B, Alessi JV, Elkrief A, Rizvi H, Wang X, Jeng M, Egger JV, Vaz VR, Barrichello A, Lamberti G, Di Federico A, Santo V, Rossato de Almeida G, Gandhi M, Clark P, Nishino M, Johnson BE, Hellmann M, Schoenfeld AJ, Awad MM. Pecci F, et al. Clin Cancer Res. 2025 Apr 18:OF1-OF13. doi: 10.1158/1078-0432.CCR-24-2990. Online ahead of print. Clin Cancer Res. 2025. PMID: 40247431
Phase I trial of hES cell-derived dopaminergic neurons for Parkinson's disease.
Tabar V, Sarva H, Lozano AM, Fasano A, Kalia SK, Yu KKH, Brennan C, Ma Y, Peng S, Eidelberg D, Tomishima M, Irion S, Stemple W, Abid N, Lampron A, Studer L, Henchcliffe C. Tabar V, et al. Nature. 2025 May;641(8064):978-983. doi: 10.1038/s41586-025-08845-y. Epub 2025 Apr 16. Nature. 2025. PMID: 40240592 Free PMC article. Clinical Trial.
A clinical benchmark of public self-supervised pathology foundation models.
Campanella G, Chen S, Singh M, Verma R, Muehlstedt S, Zeng J, Stock A, Croken M, Veremis B, Elmas A, Shujski I, Neittaanmäki N, Huang KL, Kwan R, Houldsworth J, Schoenfeld AJ, Vanderbilt C. Campanella G, et al. Nat Commun. 2025 Apr 17;16(1):3640. doi: 10.1038/s41467-025-58796-1. Nat Commun. 2025. PMID: 40240324 Free PMC article.
FOXR2 activation is not exclusive of CNS neuroblastoma.
Siskar AN, Hanzlik E, Cardenas MF, Eldomery MK, Pinto S, Tinkle CL, Zhang Q, Li X, Lin T, Dhanda SK, Reis G, Li D, Raghavan R, Vortmeyer A, Karajannis MA, Robinson GW, Onar-Thomas A, Blackburn PR, Wheeler DA, Chiang J. Siskar AN, et al. Neuro Oncol. 2025 Apr 15:noaf076. doi: 10.1093/neuonc/noaf076. Online ahead of print. Neuro Oncol. 2025. PMID: 40237561
Integrating Pulmonary and Systemic Transcriptomic Profiles to Characterize Lung Injury after Pediatric Hematopoietic Stem Cell Transplant.
Pearce EM, Evans E, Mayday MY, Reyes G, Simon MR, Blum J, Kim H, Mu J, Shaw PJ, Rowan CM, Auletta JJ, Martin PL, Hurley C, Kreml EM, Qayed M, Abdel-Azim H, Keating AK, Cuvelier GDE, Hume JR, Killinger JS, Godder K, Hanna R, Duncan CN, Quigg TC, Castillo P, Lalefar NR, Fitzgerald JC, Mahadeo KM, Satwani P, Moore TB, Hanisch B, Abdel-Mageed A, Davis DB, Hudspeth MP, Yanik GA, Pulsipher MA, Dvorak CCJL, Zinter MS. Pearce EM, et al. medRxiv [Preprint]. 2025 Apr 1:2025.03.31.25324969. doi: 10.1101/2025.03.31.25324969. medRxiv. 2025. PMID: 40236411 Free PMC article. Preprint.
CAR T-cell therapy response varies by extranodal disease site in large B-cell lymphoma.
Luna A, Devlin SM, Rejeski K, Flynn JR, Corona M, Luttwak E, Rivas-Delgado A, Landego I, Cassanello G, Gomez-Llobell M, Raj SS, Dahi PB, Lin RJ, Parascondola A, Palomba ML, Shah GL, Scordo M, Alarcon Tomas A, Leithner D, Bedmutha A, Schöder H, Imber BS, Salles G, Park JH, Perales MA, Shouval R. Luna A, et al. Blood Cancer J. 2025 Apr 14;15(1):64. doi: 10.1038/s41408-025-01273-1. Blood Cancer J. 2025. PMID: 40229268 Free PMC article.
Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling.
Cheng AP, Widman AJ, Arora A, Rusinek I, Sossin A, Rajagopalan S, Midler N, Hooper WF, Murray RM, Halmos D, Langanay T, Chu H, Inghirami G, Potenski C, Germer S, Marton M, Manaa D, Helland A, Furatero R, McClintock J, Winterkorn L, Steinsnyder Z, Wang Y, Alimohamed AI, Malbari MS, Saxena A, Callahan MK, Frederick DT, Spain L, Sigouros M, Manohar J, King A, Wilkes D, Otilano J, Elemento O, Mosquera JM, Jaimovich A, Lipson D, Turajlic S, Zody MC, Altorki NK, Wolchok JD, Postow MA, Robine N, Faltas BM, Boland G, Landau DA. Cheng AP, et al. Nat Methods. 2025 May;22(5):973-981. doi: 10.1038/s41592-025-02648-9. Epub 2025 Apr 11. Nat Methods. 2025. PMID: 40217113
Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.
Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier KR, Chittoor G, Josyula NS, Meyer M, Gupta S, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, Carlson CS, Chang KM, Chavan S, Chiu YF, Chuang LM, Conomos MP, DeMeo DL, Du M, Duggirala R, Eng C, Fohner AE, Freedman BI, Garrett ME, Guo X, Haiman C, Heavner BD, Hidalgo B, Hixson JE, Ho YL, Hobbs BD, Hu D, Hui Q, Hwu CM, Jackson RD, Jain D, Kalyani RR, Kardia SLR, Kelly TN, Lange EM, LeNoir M, Li C, Le Marchand L, McDonald MN, McHugh CP, Morrison AC, Naseri T; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; O'Connell J, O'Donnell CJ, Palmer ND, Pankow JS, Perry JA, Peters U, Preuss MH, Rao DC, Regan EA, Reupena SM, Roden DM, Rodriguez-Santana J, Sitlani CM, Smith JA, Tiwari HK, Vasan RS, Wang Z, Weeks DE, Wessel J, Wiggins KL, Wilkens LR, Wilson PWF, Yanek LR, Yoneda ZT, Zhao W, Zöllner S, Arnett DK, Ashley-Koch AE, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Carson AP, Chasman DI, Ida Chen YD, Curran JE, Fornage M, Gordeuk VR, He J, Heckbert SR, Hou L, Irvin MR, Kooperberg C, Minster RL, Mitchell BD, Nouraie M, Psaty BM, Raffield LM, Reiner AP,… See abstract for full author list ➔ Zhang X, et al. Nat Commun. 2025 Apr 11;16(1):3470. doi: 10.1038/s41467-025-58420-2. Nat Commun. 2025. PMID: 40216759 Free PMC article.
The Impact of Melphalan Conditioning and CD34 + Cell Dose and Schedule on Post-Transplant Outcomes in AL Amyloidosis.
Muchtar E, Sanchorawala V, Hassan H, Hegenbart U, Schönland S, Lee HC, Qazilbash M, Kin A, Zonder J, Jacob E, Buadi F, Dispenzieri A, Dingli D, Arai S, Chin M, Chakraborty R, Lentzsch S, Magen H, Shkury E, Sarubbi C, Landau H, Gertz M. Muchtar E, et al. Am J Hematol. 2025 Jul;100(7):1141-1151. doi: 10.1002/ajh.27685. Epub 2025 Apr 11. Am J Hematol. 2025. PMID: 40214172
Three-dimensional volumetric rendering on augmented reality headsets for ovarian cancer cytoreduction planning: A Memorial Sloan Kettering Cancer Center Team Ovary study.
Kahn RM, Murphy K, Patel T, Yeoshoua E, Tian E, Finch L, Zhou Q, Iasonos A, Booth P, Honeyman JN, Schefflein J, Crouch M, Kaza S, Broach V, Gardner GJ, Long Roche K, Sonoda Y, Abu-Rustum NR, Chi DS. Kahn RM, et al. Gynecol Oncol. 2025 May;196:107-112. doi: 10.1016/j.ygyno.2025.03.040. Epub 2025 Apr 5. Gynecol Oncol. 2025. PMID: 40187023
Real-world evaluation of teclistamab for the treatment of relapsed/refractory multiple myeloma (RRMM): an International Myeloma Working Group Study.
Tan CR, Asoori S, Huang CY, Brunaldi L, Popat R, Kastritis E, Martinez-Lopez J, Bansal R, Silva Corraes AM, Chhabra S, Parrondo R, Ailawadhi S, Fotiou D, Dimopoulos MA, Yong K, Mactier C, Lau C, Corona M, Marin AJS, Mian H, Durie BG, Usmani SZ, Martin TG, Lin Y. Tan CR, et al. Blood Cancer J. 2025 Apr 3;15(1):53. doi: 10.1038/s41408-025-01259-z. Blood Cancer J. 2025. PMID: 40175336 Free PMC article.
An inflammatory biomarker signature of response to CAR-T cell therapy in non-Hodgkin lymphoma.
Raj SS, Fei T, Fried S, Ip A, Fein JA, Leslie LA, Alarcon Tomas A, Leithner D, Peled JU, Corona M, Dahi PB, Danylesko I, Epstein-Peterson Z, Funnell T, Giralt SA, Jacoby E, Kedmi M, Landego I, Lin RJ, Parascondola A, Pascual L, Orozco N, Park JH, Palomba ML, Salles G, Saldia A, Schöder H, Sdayoor I, Shah GL, Scordo M, Shem-Tov N, Shimoni A, Slingerland J, Yerushalmi R, Nagler A, Greenbaum BD, Vickers AJ, Suh HC, Avigdor A, Perales MA, van den Brink MRM, Shouval R. Raj SS, et al. Nat Med. 2025 Apr;31(4):1183-1194. doi: 10.1038/s41591-025-03532-x. Epub 2025 Apr 1. Nat Med. 2025. PMID: 40169864 Free PMC article.
The R.O.A.D. to clinical trial emulation.
Bertsimas D, Koulouras A, Nagata H, Gao C, Mizusawa J, Kanemitsu Y, Margonis GA. Bertsimas D, et al. Res Sq [Preprint]. 2025 Mar 19:rs.3.rs-5576146. doi: 10.21203/rs.3.rs-5576146/v1. Res Sq. 2025. PMID: 40166010 Free PMC article. Preprint.
Sharing data from the Human Tumor Atlas Network through standards, infrastructure and community engagement.
de Bruijn I, Nikolov M, Lau C, Clayton A, Gibbs DL, Mitraka E, Pozhidayeva D, Lash A, Sumer SO, Altreuter J, Anton K, DeFelice M, Li X, Lisman A, Longabaugh WJR, Muhlich J, Santagata S, Nandakumar S, Sorger PK, Suver C, Doan X, Guinney J, Schultz N, Taylor AJ, Thorsson V, Cerami E, Eddy JA. de Bruijn I, et al. Nat Methods. 2025 Apr;22(4):664-671. doi: 10.1038/s41592-025-02643-0. Epub 2025 Mar 31. Nat Methods. 2025. PMID: 40164800 Review.
Treatment, toxicity, and mortality after subsequent breast cancer in female survivors of childhood cancer.
Im C, Hasan H, Stene E, Monick S, Rader RK, Sheade J, Wolfe H, Lu Z, Spector LG, McDonald AJ, Nolan V, Arnold MA, Conces MR, Moskowitz CS, Henderson TO, Robison LL, Armstrong GT, Yasui Y, Nanda R, Oeffinger KC, Neglia JP, Blaes A, Turcotte LM. Im C, et al. Nat Commun. 2025 Mar 31;16(1):3088. doi: 10.1038/s41467-025-58434-w. Nat Commun. 2025. PMID: 40164623 Free PMC article.
Germline prediction of immune checkpoint inhibitor discontinuation for immune-related adverse events.
Middha P, Thummalapalli R, Quandt Z, Balaratnam K, Cardenas E, Falcon CJ, Margaret Lung Group P, Gubens MA, Huntsman S, Khan K, Li M, Lovly CM, Patel D, Zhan LJ, Liu G, Aldrich MC, Schoenfeld A, Ziv E. Middha P, et al. J Immunother Cancer. 2025 Mar 28;13(3):e011273. doi: 10.1136/jitc-2024-011273. J Immunother Cancer. 2025. PMID: 40154961 Free PMC article.
Characterization of pritumumab in murine models and primate safety study.
Mody AA, Mukthavaram R, Jiang P, Gangangari K, Pillarsetty N, Kesari PR, Padul V, Kesari SL, Rahbarlayegh E, Glassy MC, Kesari S. Mody AA, et al. Sci Rep. 2025 Mar 25;15(1):10178. doi: 10.1038/s41598-025-95360-9. Sci Rep. 2025. PMID: 40128557 Free PMC article.
Patient outcomes in advanced ovarian cancer treated with an anti-FOLR1 antibody-drug conjugate.
Johannet P, Flint M, Chui MH, Konner J, Friedman C, Green AK, Guo R, Hensley ML, Kyi C, Liu Y, Makker V, Rubinstein M, Sabbatini P, Tew WP, Foote MB, Weigelt B, Aghajanian C, Grisham RN, O'Cearbhaill RE. Johannet P, et al. Gynecol Oncol. 2025 Apr;195:173-179. doi: 10.1016/j.ygyno.2025.03.023. Epub 2025 Mar 22. Gynecol Oncol. 2025. PMID: 40121972
TP53 mutations and TET2 deficiency cooperate to drive leukemogenesis and establish an immunosuppressive environment.
Zhang P, Whipp EC, Skuli SJ, Gharghabi M, Saygin C, Sher SA, Carroll M, Pan X, Eisenmann ED, Lai TH, Harrington BK, Chan WK, Youssef Y, Chen B, Penson A, Lewis AM, Castro CR, Fox N, Cihan A, Le Luduec JB, DeWolf S, Kauffman T, Mims AS, Canfield D, Phillips H, Williams KE, Shaffer J, Lozanski A, Doong TJ, Lozanski G, Mao C, Walker CJ, Blachly JS, Daniyan AF, Alinari L, Baiocchi RA, Yang Y, Grieselhuber NR, Campbell MJ, Baker SD, Blaser BW, Abdel-Wahab O, Lapalombella R. Zhang P, et al. J Clin Invest. 2025 Mar 20;135(10):e184021. doi: 10.1172/JCI184021. eCollection 2025 May 15. J Clin Invest. 2025. PMID: 40111422 Free PMC article.
Longitudinal Genomic Analysis to Fine-tune Targeted Therapy: Results of the Phase II LOGIC 2 Trial in Patients with BRAFV600-Mutant Metastatic Melanoma.
Dummer R, Sandhu S, Miller WH Jr, Butler MO, Taylor MH, Heinzerling L, Blank CU, Muñoz-Couselo E, Burris HA 3rd, Postow MA, Chmielowski B, Middleton MR, Berking C, Hassel JC, Gesierich AH, Mauch C, Kleha JF, Polli A, Harney AS, di Pietro A, Ascierto PA. Dummer R, et al. Clin Cancer Res. 2025 Jun 3;31(11):2097-2107. doi: 10.1158/1078-0432.CCR-24-0254. Clin Cancer Res. 2025. PMID: 40106536 Free PMC article. Clinical Trial.
Structural basis of ClC-3 inhibition by TMEM9 and PI(3,5)P2.
Schrecker M, Son Y, Planells-Cases R, Kar S, Vorobeva V, Schulte U, Fakler B, Jentsch TJ, Hite RK. Schrecker M, et al. bioRxiv [Preprint]. 2025 Mar 3:2025.02.28.640562. doi: 10.1101/2025.02.28.640562. bioRxiv. 2025. PMID: 40093093 Free PMC article. Preprint.
A potent and selective TNKS2 inhibitor for tumor-selective WNT suppression.
Zimmerman J, Malone BF, Finkin-Groner E, Sun S, Liang R, Foronda M, Schatoff EM, Granowsky E, Goswami S, Katti A, Leach B, Alcorn H, Tammela T, Fukase Y, Khan T, Huggins DJ, Ginn J, Liverton N, Hite RK, Dow LE. Zimmerman J, et al. bioRxiv [Preprint]. 2025 Mar 7:2025.03.04.641305. doi: 10.1101/2025.03.04.641305. bioRxiv. 2025. PMID: 40093088 Free PMC article. Preprint.
Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells.
Parikh C, Glenn RA, Shi Y, Chatterjee K, Kasliwal K, Swanzey EE, Singer S, Do SC, Zhan Y, Furuta Y, Tahiliani M, Apostolou E, Polyzos A, Koche R, Mezey JG, Vierbuchen T, Stadtfeld M. Parikh C, et al. Stem Cell Reports. 2025 Apr 8;20(4):102450. doi: 10.1016/j.stemcr.2025.102450. Epub 2025 Mar 13. Stem Cell Reports. 2025. PMID: 40086447 Free PMC article.
The genomic landscape of distant metastatic endometrial cancer.
Zammarrelli WA 3rd, Nandakumar S, Kertowidjojo E, Nguyen B, Moukarzel LA, Da Cruz Paula A, Rios-Doria EV, Smith SA, Momeni-Boroujeni A, Makker V, Aghajanian C, Chatila WK, Mueller JJ, Abu-Rustum NR, Schultz N, Ellenson LH, Weigelt B. Zammarrelli WA 3rd, et al. Gynecol Oncol. 2025 Apr;195:89-97. doi: 10.1016/j.ygyno.2025.03.006. Epub 2025 Mar 12. Gynecol Oncol. 2025. PMID: 40081112
Oncologic outcomes of retroperitoneal lymph node dissection following first-line chemotherapy for metastatic non-seminomatous germ-cell tumors.
Matulewicz RS, Baky F, Liso N, Williams BM, Porwal S, Assel M, Carver BS, Bajorin DF, Motzer RJ, Bosl GJ, McHugh DJ, Reuter VE, Tickoo SK, Al-Ahmadie H, Vickers AJ, Funt SA, Feldman DR, Sheinfeld J. Matulewicz RS, et al. Ann Oncol. 2025 Jun;36(6):693-703. doi: 10.1016/j.annonc.2025.03.002. Epub 2025 Mar 10. Ann Oncol. 2025. PMID: 40073938
Engineering mtDNA deletions by reconstituting end joining in human mitochondria.
Fu Y, Land M, Kavlashvili T, Cui R, Kim M, DeBitetto E, Lieber T, Ryu KW, Choi E, Masilionis I, Saha R, Takizawa M, Baker D, Tigano M, Lareau CA, Reznik E, Sharma R, Chaligne R, Thompson CB, Pe'er D, Sfeir A. Fu Y, et al. Cell. 2025 May 15;188(10):2778-2793.e21. doi: 10.1016/j.cell.2025.02.009. Epub 2025 Mar 10. Cell. 2025. PMID: 40068680
Prospective evaluation of structure-based simulations reveal their ability to predict the impact of kinase mutations on inhibitor binding.
Singh S, Gapsys V, Aldeghi M, Schaller D, Rangwala AM, White JB, Bluck JP, Scheen J, Glass WG, Guo J, Hayat S, de Groot BL, Volkamer A, Christ CD, Seeliger MA, Chodera JD. Singh S, et al. bioRxiv [Preprint]. 2025 Mar 1:2024.11.15.623861. doi: 10.1101/2024.11.15.623861. bioRxiv. 2025. Update in: J Phys Chem B. 2025 Mar 20;129(11):2882-2902. doi: 10.1021/acs.jpcb.4c07794. PMID: 40060600 Free PMC article. Updated. Preprint.
Evaluation of physical function and quality of life before and after nonradical surgical therapy for stage IA1 and IA2-IB1 cervical cancer (GOG-0278).
Carter J, Huang HQ, Monk BJ, Kim YB, Kim MH, Stuckey A, Vicus DL, Holman LL, Fleury AC, Pearson JM, Thawani N, Shahin M, Lea J, Robertson SE, Warshal D, Backes FJ, Feltmate C, Wilkinson-Ryan I, Covens A. Carter J, et al. Gynecol Oncol. 2025 Apr;195:50-58. doi: 10.1016/j.ygyno.2025.02.023. Epub 2025 Mar 9. Gynecol Oncol. 2025. PMID: 40058184
Evaluation of efficacy and fertility after nonradical surgical therapy (extra fascial hysterectomy or cone biopsy, with pelvic lymphadenectomy) for stage IA1, IA2, and IB1 cervical cancer (GOG-0278).
Covens A, Huang HQ, Monk BJ, Kim YB, Kim MH, DiSilvestro P, Vicus D, Holman LL, Fleury A, Pearson JM, Thawani N, Shahin MS, Lea JS, Robertson SE, Warshal D, Backes F, Feltmate C, Dewdney S, Leitao MM, Wilkinson-Ryan I, Elsayed AG, Carter J. Covens A, et al. Gynecol Oncol. 2025 Apr;195:59-65. doi: 10.1016/j.ygyno.2025.03.005. Epub 2025 Mar 7. Gynecol Oncol. 2025. PMID: 40056831
Prospective Evaluation of Structure-Based Simulations Reveal Their Ability to Predict the Impact of Kinase Mutations on Inhibitor Binding.
Singh S, Gapsys V, Aldeghi M, Schaller D, Rangwala AM, White JB, Bluck JP, Scheen J, Glass WG, Guo J, Hayat S, de Groot BL, Volkamer A, Christ CD, Seeliger MA, Chodera JD. Singh S, et al. J Phys Chem B. 2025 Mar 20;129(11):2882-2902. doi: 10.1021/acs.jpcb.4c07794. Epub 2025 Mar 7. J Phys Chem B. 2025. PMID: 40053698 Free PMC article.
Symptomatic Prostate-Specific Membrane Antigen PET-Positive Radionecrosis After Multimodality Brain Metastasis-Directed Treatment Including [177Lu]Lu-PSMA-617.
Imber BS, Yu KKH, Abida W, Pike LRG, Grkovski M, Kaley TJ, Morris MJ, Bodei L, Nosov A, Dunphy MPS, Schöder H, Fox JJ, Rosenblum M, Bale T, Krebs S. Imber BS, et al. J Nucl Med. 2025 Mar 6:jnumed.124.269175. doi: 10.2967/jnumed.124.269175. Online ahead of print. J Nucl Med. 2025. PMID: 40049744 No abstract available.
Health-Related Quality of Life for Persons Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions (AMC-A01).
Atkinson TM, Mazumdar M, Van Hyfte G, Lee JY, Li Y, Lynch KA, Webb A, Holland SM, Lubetkin EI, Goldstone S, Einstein MH, Stier EA, Wiley DJ, Mitsuyasu R, Rosa-Cunha I, Aboulafia DM, Dhanireddy S, Schouten JT, Levine R, Gardner EM, Dunlevy H, Barroso LF, Bucher G, Korman J, Stearn B, Wilkin TJ, Ellsworth G, Pugliese JC, Cella D, Berry-Lawhorn JM, Palefsky JM. Atkinson TM, et al. JCO Oncol Pract. 2025 Mar 6:OP2400830. doi: 10.1200/OP-24-00830. Online ahead of print. JCO Oncol Pract. 2025. PMID: 40048673
Regulation of VEGFR3 signaling in lymphatic endothelial cells.
Kuonqui KG, Campbell AC, Pollack BL, Shin J, Sarker A, Brown S, Park HJ, Mehrara BJ, Kataru RP. Kuonqui KG, et al. Front Cell Dev Biol. 2025 Feb 13;13:1527971. doi: 10.3389/fcell.2025.1527971. eCollection 2025. Front Cell Dev Biol. 2025. PMID: 40046235 Free PMC article. Review.
Hepatic Stellate Cells Functional Heterogeneity in Liver Cancer.
Sererols-Viñas L, Garcia-Vicién G, Ruiz-Blázquez P, Lee TF, Lee YA, Gonzalez-Sanchez E, Vaquero J, Moles A, Filliol A, Affò S. Sererols-Viñas L, et al. Semin Liver Dis. 2025 Mar;45(1):33-51. doi: 10.1055/a-2551-0724. Epub 2025 Mar 5. Semin Liver Dis. 2025. PMID: 40043738 Review.
Paired primary-metastasis patient-derived organoids and mouse models identify phenotypic evolution and druggable dependencies of peritoneal metastasis from appendiceal cancer.
Mahmoud A, Choi PH, Sukhwa C, Pintar J, Walch H, Zhao N, Bermeo J, Chung S, Raghavan M, Bapat S, Jiang Q, Karagkounis G, Meredith J, Giarrizzo M, Firat C, Cercek A, Foote MB, Schultz N, Chatila WK, Nash GM, Shia J, Sanchez-Vega F, Larson S, Dar AC, Rosen N, Ganesh K. Mahmoud A, et al. bioRxiv [Preprint]. 2025 Feb 22:2025.02.17.638725. doi: 10.1101/2025.02.17.638725. bioRxiv. 2025. PMID: 40027618 Free PMC article. Preprint.
Preliminary Results: Comparison of Convolutional Neural Network Architectures as an Auxiliary Clinical Tool Applied to Screening Mammography in Mexican Women.
Acosta-Jiménez S, González-Chávez SA, Camarillo-Cisneros J, Pacheco-Tena C, Barcenas-López M, González-Lozada LE, Hernández-Orozco C, Burboa-Delgado JH, Ochoa-Albíztegui RE. Acosta-Jiménez S, et al. J Med Biol Eng. 2024 Jun;44(3):390-400. doi: 10.1007/s40846-024-00868-6. Epub 2024 May 9. J Med Biol Eng. 2024. PMID: 40027073 Free PMC article.
Multimodal histopathologic models stratify hormone receptor-positive early breast cancer.
Boehm KM, El Nahhas OSM, Marra A, Waters M, Jee J, Braunstein L, Schultz N, Selenica P, Wen HY, Weigelt B, Paul ED, Cekan P, Erber R, Loeffler CML, Guerini-Rocco E, Fusco N, Frascarelli C, Mane E, Munzone E, Dellapasqua S, Zagami P, Curigliano G, Razavi P, Reis-Filho JS, Pareja F, Chandarlapaty S, Shah SP, Kather JN. Boehm KM, et al. Nat Commun. 2025 Mar 2;16(1):2106. doi: 10.1038/s41467-025-57283-x. Nat Commun. 2025. PMID: 40025017 Free PMC article.
Towards opioid access without excess.
Rosa WE, Knaul FM, Touchton M, Bhadelia A, Humphreys K, Radbruch L, Rajagopal MR. Rosa WE, et al. Lancet Public Health. 2025 May;10(5):e422-e427. doi: 10.1016/S2468-2667(25)00035-0. Epub 2025 Feb 26. Lancet Public Health. 2025. PMID: 40023173 Free PMC article. Review.
The evolution of serious health-related suffering from 1990 to 2021: an update to The Lancet Commission on global access to palliative care and pain relief.
Knaul FM, Arreola-Ornelas H, Kwete XJ, Bhadelia A, Rosa WE, Touchton M, Méndez-Carniado O, Vargas Enciso V, Pastrana T, Friedman JR, Connor SR, Downing J, Jamison DT, Krakauer EL, Watkins D, Calderon-Anyosa R, Garcia-Santisteban R, Nargund RS, Cleary J, De Lima L, Gafer N, Grant L, Ntizimira C, Pérez-Cruz PE, Rajagopal MR, Spence D, Vila P, Radbruch L. Knaul FM, et al. Lancet Glob Health. 2025 Mar;13(3):e422-e436. doi: 10.1016/S2214-109X(24)00476-5. Lancet Glob Health. 2025. PMID: 40021301 Free PMC article.
Metabolic engineering to facilitate anti-tumor immunity.
Schild T, Wallisch P, Zhao Y, Wang YT, Haughton L, Chirayil R, Pierpont K, Chen K, Nunes-Violante S, Cross J, de Stanchina E, Thompson CB, Scheinberg DA, Perry JSA, Keshari KR. Schild T, et al. Cancer Cell. 2025 Mar 10;43(3):552-562.e9. doi: 10.1016/j.ccell.2025.02.004. Epub 2025 Feb 27. Cancer Cell. 2025. PMID: 40020672
RBM10 loss promotes metastases by aberrant splicing of cytoskeletal and extracellular matrix mRNAs.
Krishnamoorthy GP, Glover AR, Untch BR, Sigcha-Coello N, Xu B, Vukel D, Liu Y, Tiedje V, Pineda JMB, Berman K, Tamarapu PP, Acuña-Ruiz A, Saqcena M, de Stanchina E, Boucai L, Ghossein RA, Knauf JA, Abdel-Wahab O, Bradley RK, Fagin JA. Krishnamoorthy GP, et al. J Exp Med. 2025 May 5;222(5):e20241029. doi: 10.1084/jem.20241029. Epub 2025 Feb 24. J Exp Med. 2025. PMID: 39992626
A multi-institutional retrospective cohort of adult-onset medulloblastoma in the modern era.
Bonm AV, Rutenberg MS, Therkelsen KE, Herbst J, Sanaf A, Sherwood MA, Rhee JY, McGranahan TM, Cimino PJ, Gonzalez Castro LN, Tsang DS, Karajannis MA, Nagpal S, Amdur RJ, Shih H, Barber J, Taylor LP. Bonm AV, et al. Neurooncol Adv. 2025 Jan 22;7(1):vdae231. doi: 10.1093/noajnl/vdae231. eCollection 2025 Jan-Dec. Neurooncol Adv. 2025. PMID: 39991182 Free PMC article.
Systems-Level Interactome Mapping Reveals Actionable Protein Network Dysregulation Across the Alzheimer's Disease Spectrum.
Bay S, Rodina A, Haut F, Roychowdhury T, Argyrousi EK, Staniszewski A, Han K, Sharma S, Chakrabarty S, Digwal CS, Stanisavljevic A, Labuza A, Alldred MJ, Panchal P, SanthaSeela A, Tuffery L, Li Z, Hashmi A, Rosiek E, Chan E, Monetti M, Sasaguri H, Saido TC, Schneider JA, Bennett DA, Fraser PE, Erdjument-Bromage H, Neubert TA, Ginsberg SD, Arancio O, Chiosis G. Bay S, et al. Res Sq [Preprint]. 2025 Feb 12:rs.3.rs-5930673. doi: 10.21203/rs.3.rs-5930673/v1. Res Sq. 2025. PMID: 39989971 Free PMC article. Preprint.
Solute carriers: The gatekeepers of metabolism.
Khan A, Liu Y, Gad M, Kenny TC, Birsoy K. Khan A, et al. Cell. 2025 Feb 20;188(4):869-884. doi: 10.1016/j.cell.2025.01.015. Cell. 2025. PMID: 39983672 Review.
Selpercatinib in RET Fusion-Positive Non-Small Cell Lung Cancer: Final Safety and Efficacy, Including Overall Survival, From the LIBRETTO-001 Phase I/II Trial.
Gautschi O, Park K, Solomon BJ, Tomasini P, Loong HH, De Braud F, Goto K, Peterson P, Barker S, Liming K, Oxnard GR, Frimodt-Moller B, Drilon A. Gautschi O, et al. J Clin Oncol. 2025 May 20;43(15):1758-1764. doi: 10.1200/JCO-24-02076. Epub 2025 Feb 21. J Clin Oncol. 2025. PMID: 39983053 Free PMC article. Clinical Trial.
Outcomes of patients with Richter transformation who received no prior chemoimmunotherapy for their CLL.
Kittai AS, Huang Y, Miller S, Allan JN, Bhat SA, Bond DA, Brander DM, Byrd JC, Chavez JC, Chong E, Davids MS, Danilov AV, Ding W, Dowling MR, Dvorak-Kornaus K, Freedman H, Hampel PJ, Ho C, Hwang SR, Islam P, Malakhov N, Matasar M, Miller C, Omer Z, Parikh SA, Parry E, Rabe KG, Raess PW, Rai M, Roeker L, Rhodes J, Rogers KA, Saha A, Schade J, Scott HW, Shadman M, Shouse G, Skarbnik A, Spurgeon S, Stephens DM, Thompson MC, Thompson PA, Wang Y, Yano M, Woyach JA. Kittai AS, et al. Blood Cancer J. 2025 Feb 20;15(1):23. doi: 10.1038/s41408-025-01236-6. Blood Cancer J. 2025. PMID: 39979241 Free PMC article. No abstract available.
The Absolute Volume of Gleason Pattern 4 on Radical Prostatectomy Is More Strongly Associated With Advanced Stage and Biochemical Recurrence Than Gleason Grade Groups.
Scuderi S, Tin AL, Klug J, Porwal S, Quarta L, Ciabattini M, Tenace NP, Leni R, Lucianò R, Stabile A, Gandaglia G, Eastham JA, Montorsi F, Briganti A, Vickers AJ. Scuderi S, et al. J Urol. 2025 Jun;213(6):722-729. doi: 10.1097/JU.0000000000004484. Epub 2025 Feb 20. J Urol. 2025. PMID: 39977387
Wearable penile devices: the TechRing.
Saffati G, Rendon DO, Daily R, Khera M, Mulhall JP. Saffati G, et al. Transl Androl Urol. 2025 Jan 31;14(1):152-157. doi: 10.21037/tau-24-548. Epub 2025 Jan 21. Transl Androl Urol. 2025. PMID: 39974806 Free PMC article.
Tumour-wide RNA splicing aberrations generate actionable public neoantigens.
Kwok DW, Stevers NO, Etxeberria I, Nejo T, Colton Cove M, Chen LH, Jung J, Okada K, Lakshmanachetty S, Gallus M, Barpanda A, Hong C, Chan GKL, Liu J, Wu SH, Ramos E, Yamamichi A, Watchmaker PB, Ogino H, Saijo A, Du A, Grishanina NR, Woo J, Diaz A, Hervey-Jumper SL, Chang SM, Phillips JJ, Wiita AP, Klebanoff CA, Costello JF, Okada H. Kwok DW, et al. Nature. 2025 Mar;639(8054):463-473. doi: 10.1038/s41586-024-08552-0. Epub 2025 Feb 19. Nature. 2025. PMID: 39972144 Free PMC article.
Cooperative nutrient scavenging is an evolutionary advantage in cancer.
Guzelsoy G, Elorza SD, Ros M, Schachtner LT, Hayashi M, Hobson-Gutierrez S, Rundstrom P, Brunner JS, Pillai R, Walkowicz WE, Finley LWS, Deforet M, Papagiannakopoulos T, Carmona-Fontaine C. Guzelsoy G, et al. Nature. 2025 Apr;640(8058):534-542. doi: 10.1038/s41586-025-08588-w. Epub 2025 Feb 19. Nature. 2025. PMID: 39972131 Free PMC article.
Reconstitution of SPO11-dependent double-strand break formation.
Zheng Z, Zheng L, Arter M, Liu K, Yamada S, Ontoso D, Kim S, Keeney S. Zheng Z, et al. Nature. 2025 Mar;639(8055):784-791. doi: 10.1038/s41586-025-08601-2. Epub 2025 Feb 19. Nature. 2025. PMID: 39972129 Free PMC article.
RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer.
Sethna Z, Guasp P, Reiche C, Milighetti M, Ceglia N, Patterson E, Lihm J, Payne G, Lyudovyk O, Rojas LA, Pang N, Ohmoto A, Amisaki M, Zebboudj A, Odgerel Z, Bruno EM, Zhang SL, Cheng C, Elhanati Y, Derhovanessian E, Manning L, Müller F, Rhee I, Yadav M, Merghoub T, Wolchok JD, Basturk O, Gönen M, Epstein AS, Momtaz P, Park W, Sugarman R, Varghese AM, Won E, Desai A, Wei AC, D'Angelica MI, Kingham TP, Soares KC, Jarnagin WR, Drebin J, O'Reilly EM, Mellman I, Sahin U, Türeci Ö, Greenbaum BD, Balachandran VP. Sethna Z, et al. Nature. 2025 Mar;639(8056):1042-1051. doi: 10.1038/s41586-024-08508-4. Epub 2025 Feb 19. Nature. 2025. PMID: 39972124 Free PMC article. Clinical Trial.
Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases.
Mitchell J, Camacho N, Shea P, Stopsack KH, Joseph V, Burren OS, Dhindsa RS, Nag A, Berchuck JE, O'Neill A, Abbasi A, Zoghbi AW, Alegre-Díaz J, Kuri-Morales P, Berumen J, Tapia-Conyer R, Emberson J, Torres JM, Collins R, Wang Q, Goldstein D, Matakidou A, Haefliger C, Anderson-Dring L, March R, Jobanputra V, Dougherty B, Carss K, Petrovski S, Kantoff PW, Offit K, Mucci LA, Pomerantz M, Fabre MA. Mitchell J, et al. Nat Commun. 2025 Feb 19;16(1):1779. doi: 10.1038/s41467-025-56944-1. Nat Commun. 2025. PMID: 39971927 Free PMC article.
Post-Acute Transition to Home With Supportive Care (PATHS): A Novel Nurse Practitioner-Led Telehealth Intervention to Improve End-of-Life Oncology Care.
Rosa WE, Epstein AS, Lauria T, Qualters K, Kapoor-Hintzen N, Knezevic A, Egan B, Levine M, Koo DJ, Gandham A, Nelson JE. Rosa WE, et al. J Pain Symptom Manage. 2025 May;69(5):496-506. doi: 10.1016/j.jpainsymman.2025.02.008. Epub 2025 Feb 17. J Pain Symptom Manage. 2025. PMID: 39971213 Free PMC article.
Spaceflight Associated Neuro-ocular Syndrome (SANS) and its countermeasures.
Nguyen T, Ong J, Brunstetter T, Gibson CR, Macias BR, Laurie S, Mader T, Hargens A, Buckey JC, Lan M, Wostyn P, Kadipasaoglu C, Smith SM, Zwart SR, Frankfort BJ, Aman S, Scott JM, Waisberg E, Masalkhi M, Lee AG. Nguyen T, et al. Prog Retin Eye Res. 2025 May;106:101340. doi: 10.1016/j.preteyeres.2025.101340. Epub 2025 Feb 17. Prog Retin Eye Res. 2025. PMID: 39971096 Review.
Carbohydrate antigen 19-9 (CA19-9) response after induction FOLFIRINOX for locally advanced pancreatic cancer identifies patients who may benefit from surgical exploration: multicentre, observational cohort study.
Dekker EN, van Klaveren D, Verkolf EMM, de Wilde RF, Besselink MG, O'Reilly EM, Paniccia A, Katz MHG, Tzeng CD, Wei AC, Zureikat AH, Groot Koerkamp B; Trans-Atlantic Pancreatic Surgery (TAPS) Consortium. Dekker EN, et al. Br J Surg. 2025 Feb 1;112(2):znaf011. doi: 10.1093/bjs/znaf011. Br J Surg. 2025. PMID: 39967445 Free PMC article.
Pan-Cancer Analysis of Oncogenic MET Fusions Reveals Distinct Pathogenomic Subsets with Differential Sensitivity to MET-Targeted Therapy.
Febres-Aldana CA, Vojnic M, Odintsov I, Zhang T, Cheng R, Beach CZ, Lu D, Mattar MS, Gazzo AM, Gili L, Harshan M, Ameri A, Machnicki S, Xiao X, Lockwood WW, Zhou XY, Yao Q, Drilon A, Rekhtman N, Shah N, Li A, Liu Z, Yang SR, Davare MA, Ladanyi M, Somwar R. Febres-Aldana CA, et al. Cancer Discov. 2025 Jun 3;15(6):1141-1158. doi: 10.1158/2159-8290.CD-24-0417. Cancer Discov. 2025. PMID: 39965191
The LYMPH trial: comparing microsurgical with conservative treatment for chronic breast cancer-associated lymphoedema - study protocol of a pragmatic randomised international multicentre superiority trial.
Kappos EA, Haas Y, Schulz A, Peters F, Savanthrapadian S, Stoffel J, Katapodi MC, Mucklow R, Kaiser B, Haumer A, Etter S, Cattaneo M, Staub D, Ribi K, Shaw J, Handschin TM, Eisenhardt S, Visconti G, Franceschini G, Scardina L, Longo B, Vetter M, Zaman K, Plock JA, Scaglioni M, Gonzalez EG, Quildrian SD, Felmerer G, Mehrara BJ, Ayala JM, Pons G, Kalbermatten DF, Sacks JM, Halle M, Muntean MV, Taylor EM, Mani M, Jung FJ, di Summa PG, Demiri E, Dionyssiou D, Groth AK, Heine N, Vorstenborsch J, Isaac KV, Qiu SS, Engels PE, Serre A, Eberhardt AL, Ebner S, Schwenkglenks M, Stoel Y, Leo C, Horch RE, Blondeel P, Behr B, Kneser U, Prantl L, Boll DT, Granziera C, Hemkens L, Lindenblatt N, Haug M, Schaefer DJ, Hirche C, Pusic AL, Seidenstuecker K, Harder Y, Weber W. Kappos EA, et al. BMJ Open. 2025 Feb 17;15(2):e090662. doi: 10.1136/bmjopen-2024-090662. BMJ Open. 2025. PMID: 39961719 Free PMC article.
Methodologic Approach to Defining Comorbidities in a Cohort of Patients With Cancer: An Example in the Optimal Breast Cancer Chemotherapy Dosing Study.
Wang P, O'Connell K, Bhimani J, Blinder V, Burganowski R, Ergas IJ, Gallagher GB, Griggs JJ, Heon N, Kolevska T, Kotsurovskyy Y, Kroenke CH, Laurent CA, Liu R, Nakata KG, Persaud S, Rivera DR, Roh JM, Tabatabai S, Valice E, Bandera EV, Kushi LH, Aiello Bowles EJ, Kantor ED. Wang P, et al. JCO Clin Cancer Inform. 2025 Feb;9:e2400231. doi: 10.1200/CCI-24-00231. Epub 2025 Feb 14. JCO Clin Cancer Inform. 2025. PMID: 39951671
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