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1992 1
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1999 3
2000 2
2001 2
2002 3
2003 4
2004 5
2005 8
2006 4
2007 9
2008 15
2009 23
2010 32
2011 39
2012 60
2013 102
2014 100
2015 92
2016 116
2017 163
2018 210
2019 200
2020 236
2021 201
2022 156
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Page 1
Cross-sectional evaluation of exposure to ozone, nitrogen dioxide, and particulate mass levels on circulating immune markers in women in the California Teachers Study.
Cauble EL, Kleeman MJ, Zhao Y, Franklin M, Yao M, Spielfogel ES, Benmarhnia T, Lacey JV, Elkind MSV, Zhao J, Magpantay L, Martinez-Maza O, Wang SS, Epeldegui M. Cauble EL, et al. Res Sq [Preprint]. 2025 Sep 30:rs.3.rs-7566245. doi: 10.21203/rs.3.rs-7566245/v1. Res Sq. 2025. Update in: Sci Rep. 2025 Dec 5. doi: 10.1038/s41598-025-30900-x. PMID: 41255994 Free PMC article. Updated. Preprint.
Elevated Microbially-Derived Metabolites in Autism: A Possible Diagnostic Screening Test for a Distinct ASD Phenotype.
Flynn C, Carr K, Whiteley P, Nirmalkar K, Bellinghiere A, Hahn J, Liu H, Arici H, Hewitson L, Devlin M, Pollard E, Pathak K, Garcia K, Rosales A, Pirrotte P, Kalb D, Keen R, Kenyon V, Fasano A, Krajmalnik-Brown R, Adams J. Flynn C, et al. Res Sq [Preprint]. 2025 Oct 2:rs.3.rs-7643826. doi: 10.21203/rs.3.rs-7643826/v1. Res Sq. 2025. PMID: 41255972 Free PMC article. Preprint.
STX4 Is Indispensable for Mitochondrial Homeostasis in Skeletal Muscle.
Hoolachan JM, Balakrishnan R, McCown EM, Merz KE, Zhou C, Bloom-Saldana E, Fueger PT, Hamilton A, Kiperman T, Ma K, Oh E, Jiang L, Pirrotte P, Shirihai O, Thurmond DC. Hoolachan JM, et al. J Cachexia Sarcopenia Muscle. 2025 Dec;16(6):e70113. doi: 10.1002/jcsm.70113. J Cachexia Sarcopenia Muscle. 2025. PMID: 41214862 Free PMC article.
Diploid genome assembly of human fibroblast cell lines enables clone specific variant calling, improved read mapping and accurate phasing.
Ranallo-Benavidez TR, Hao Y, Volpe E, Jehangir M, Fukushima N, Mbegbu O, Reiman R, Molnar J, Murphy D, Paredes DM, Wong S, Karaniuk K, Buchholtz S, Keats J, Machiela MJ, Kolmogorov M, Paten B, Giunta S, Barthel FP. Ranallo-Benavidez TR, et al. bioRxiv [Preprint]. 2025 Apr 15:2025.04.15.648829. doi: 10.1101/2025.04.15.648829. bioRxiv. 2025. PMID: 41030990 Free PMC article. Preprint.
Safety and Efficacy of Cisplatin and Doxorubicin Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Patients with Ovarian Cancer with Peritoneal Metastases: A Multicenter US Phase I Trial.
Nakamura B, Senguttuvan R, Ruel NH, Frankel PH, Yost SE, Cole S, Chang S, Jung A, Eng M, Tinsley R, Synold T, Stewart D, Wang E, Cohen J, Villella J, Whelan RL, Merchea A, DePeralta DK, Woo Y, Raoof M, Dellinger TH. Nakamura B, et al. Ann Surg Oncol. 2026 Jan;33(1):415-425. doi: 10.1245/s10434-025-18432-0. Epub 2025 Sep 30. Ann Surg Oncol. 2026. PMID: 41028642 Free PMC article. Clinical Trial.
DNA2 and MSH2 cooperatively repair stabilized G4 and allow efficient telomere replication.
Fernandez A, Zhou T, Lei Y, Liu N, Esworthy S, Shen C, Liu H, Hess JD, Yuan H, Shi G, Zhou M, Shen L, Zhang S, Kosiyatrakul S, Gaur V, Sommers JA, Srivastava N, Edelmann W, Li GM, Brosh RM Jr, Chai W, Lee MYWT, Zhang D, Schildkraut C, Zheng L, Shen B. Fernandez A, et al. Nat Commun. 2025 Sep 26;16(1):8519. doi: 10.1038/s41467-025-63505-z. Nat Commun. 2025. PMID: 41006252 Free PMC article.
Whole exome sequencing identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer in Hispanic/Latina women.
Nierenberg JL, Adamson AW, Hu D, Huntsman S, Patrick C, Li M, Steele L, Tao S, Ding YC, Tong B, Shieh Y, Fejerman L, Gruber SB, Haiman CA, John EM, Kushi LH, Torres-Mejía G, Ricker C, Weitzel JN, Ziv E, Neuhausen SL. Nierenberg JL, et al. Nat Commun. 2025 Aug 21;16(1):7816. doi: 10.1038/s41467-025-60564-0. Nat Commun. 2025. PMID: 40841357 Free PMC article.
Chlorotoxin-directed CAR T cell therapy for recurrent glioblastoma: Interim clinical experience demonstrating feasibility and safety.
Barish ME, Aftabizadeh M, Hibbard J, Blanchard MS, Ostberg JR, Wagner JR, Manchanda M, Paul J, Stiller T, Aguilar B, Starr R, Arvanitis L, Ressler JA, Kilpatrick J, Kong Y, Wang D, Forman SJ, D'Apuzzo M, Brown CE, Badie B. Barish ME, et al. Cell Rep Med. 2025 Aug 19;6(8):102302. doi: 10.1016/j.xcrm.2025.102302. Epub 2025 Aug 15. Cell Rep Med. 2025. PMID: 40818458 Free PMC article. Clinical Trial.
Universal off-the-shelf combination immunotherapy using oncolytic viruses to redirect T cell engagers to target solid tumors.
Park AK, Monroy I, Ren Y, Lu C, Chaurasiya S, Valencia H, Lent-Koop J, Cook C, Kang S, Lopez L, Murad JP, Yamaguchi Y, Urak R, Chang WC, Shah M, Chong LMO, Fong Y, Forman SJ, Wang X, Priceman SJ. Park AK, et al. J Immunother Cancer. 2025 Aug 11;13(8):e011051. doi: 10.1136/jitc-2024-011051. J Immunother Cancer. 2025. PMID: 40789743 Free PMC article.
ALKBH1 Drives Tumorigenesis and Drug Resistance via tRNA-decoding Reprogramming and Codon-biased Translation.
Shen C, Che Y, Zhou K, Wang K, Li W, Xue D, Wu T, Yang L, Chen M, Sheng Y, Zhang C, Robinson S, Chen H, Sau L, Chen Z, Wunderlich M, Han L, Tang T, Qing Y, Wu D, Sun M, Leung K, Dąbrowska K, Pirrotte P, Hu YC, Ghoda LY, Zhang B, Mulloy JC, Wei M, Marcucci G, He C, Deng X, Chen J. Shen C, et al. Cancer Discov. 2025 Nov 3;15(11):2298-2325. doi: 10.1158/2159-8290.CD-24-1043. Cancer Discov. 2025. PMID: 40747882 Free PMC article.
Outcomes after Melphalan-Based Reduced Intensity Allogeneic Hematopoietic Cell Transplantation in Renal Impairment.
Nguyen T, Markary T, Tsai NC, Tiemann K, Mokhtari S, Samara Y, Pourhassan H, Blackmon A, Arslan S, Otoukesh S, Agarwal V, Amanam I, Ball B, Koller P, Aribi A, Salhotra A, Sandhu K, Pullarkat V, Becker P, Aldoss I, Ali H, Stewart F, Smith E, Stein A, Marcucci G, Forman SJ, Artz A, Nakamura R, Al Malki MM. Nguyen T, et al. Transplant Cell Ther. 2025 Oct;31(10):824.e1-824.e13. doi: 10.1016/j.jtct.2025.07.001. Epub 2025 Jul 3. Transplant Cell Ther. 2025. PMID: 40617293
Hormone therapy use and young-onset breast cancer: a pooled analysis of prospective cohorts included in the Premenopausal Breast Cancer Collaborative Group.
O'Brien KM, House MG, Goldberg M, Jones ME, Weinberg CR, de Gonzalez AB, Bertrand KA, Blot WJ, DeHart JC, Couch FJ, Garcia-Closas M, Giles GG, Kirsh VA, Kitahara CM, Koh WP, Park HL, Milne RL, Palmer JR, Patel AV, Rohan TE, Schoemaker MJ, Swerdlow AJ, Teras LR, Vachon C, Visvanathan K, Yuan JM, Zheng W, Nichols HB, Sandler DP. O'Brien KM, et al. Lancet Oncol. 2025 Jul;26(7):911-923. doi: 10.1016/S1470-2045(25)00211-6. Lancet Oncol. 2025. PMID: 40609572
Community Water Trihalomethanes and Chronic Kidney Disease.
Medgyesi DN, Mohan S, Bangia K, Spielfogel ES, Spaur M, Fisher JA, Madrigal JM, Navas-Acien A, Beane Freeman LE, Jones RR, Ward MH, Lacey JV Jr, Sanchez TR. Medgyesi DN, et al. JAMA Netw Open. 2025 Jul 1;8(7):e2518513. doi: 10.1001/jamanetworkopen.2025.18513. JAMA Netw Open. 2025. PMID: 40601319 Free PMC article.
Residential Segregation and Lung Cancer Risk in African American Adults.
Xiao Y, Zou X, Tribby CP, Vien P, Chang C, Curley RJ, Akande O, Aldrich MC, Wang S, Kittles RA, Ashing K, Wong FL, Jankowska MM, Benmarhnia T, Erhunmwunsee L. Xiao Y, et al. JAMA Netw Open. 2025 Jul 1;8(7):e2518481. doi: 10.1001/jamanetworkopen.2025.18481. JAMA Netw Open. 2025. PMID: 40591357 Free PMC article.
Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T-Cell Lymphoma.
Bouska A, Zhang W, Sharma S, Holte H, Shah RA, Lone WG, Soma MA, Yang R, Liu X, Mehmood S, Chawla RS, Cappelli LV, Fiore D, Gong Q, Heavican-Foral TB, Cannatella JJ, Amador C, Arif A, Smith LM, Lim ST, Ong CK, Feldman AL, Du MQ, Perry AM, de Leval L, Greiner TC, Fu K, Trøen G, Vodák D, Nakken S, Delabie J, Weinstock D, Pileri S, Laginestra A, Kim K, Pajvani U, Vose JM, Weisenburger DD, Horwitz SM, Dave S, Khoury J, Inghirami G, Chan WC, Iqbal J. Bouska A, et al. Am J Hematol. 2025 Sep;100(9):1486-1501. doi: 10.1002/ajh.27736. Epub 2025 Jun 13. Am J Hematol. 2025. PMID: 40510016 Free PMC article.
DNA2 and FANCM function in two distinctive pathways in disrupting TERRA R-loops and suppressing replication stress at ALT telomeres.
Ragupathi A, Abid HZ, Chen Y, Zhao R, Kosiyatrakul ST, Yetil DI, Neiswander J, Feltman R, Thomas S, Yusupov B, Singh M, Zheng L, Shen B, Zhang H, Chu HC, Schildkraut CL, Xiao M, Zhang D. Ragupathi A, et al. bioRxiv [Preprint]. 2025 May 24:2025.05.22.655602. doi: 10.1101/2025.05.22.655602. bioRxiv. 2025. PMID: 40475582 Free PMC article. Preprint.
CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphoma.
Xavier S, Nguyen V, Khairnar V, Phan A, Yang L, Nelson MS, Shukla RP, Wang J, Li A, Geng H, Lee J, Sadras T, Pham LV, Weisenburger DD, Chan WC, Lang KS, Shouse GP, Danilov AV, Song JY, Parekh S, Müschen M, Ngo VN. Xavier S, et al. Nat Commun. 2025 May 29;16(1):4967. doi: 10.1038/s41467-025-60208-3. Nat Commun. 2025. PMID: 40436855 Free PMC article.
Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification.
Zanti M, O'Mahony DG, Parsons MT, Dorling L, Dennis J, Boddicker NJ, Chen W, Hu C, Naven M, Yiangou K, Ahearn TU, Ambrosone CB, Andrulis IL, Antoniou AC, Auer PL, Baynes C, Bodelon C, Bogdanova NV, Bojesen SE, Bolla MK, Brantley KD, Camp NJ, Campbell A, Castelao JE, Cessna MH, Chang-Claude J, Chen F, Chenevix-Trench G; NBCS Collaborators; Conroy DM, Czene K, De Nicolo A, Domchek SM, Dörk T, Dunning AM, Eliassen AH, Evans DG, Fasching PA, Figueroa JD, Flyger H, Gago-Dominguez M, García-Closas M, Glendon G, González-Neira A, Grassmann F, Hadjisavvas A, Haiman CA, Hamann U, Hart SN, Hartman MBA, Ho WK, Hodge JM, Hoppe R, Howell SJ; kConFab Investigators; Jakubowska A, Khusnutdinova EK, Ko YD, Kraft P, Kristensen VN, Lacey JV, Li J, Lim GH, Lindström S, Lophatananon A, Luccarini C, Mannermaa A, Martinez ME, Mavroudis D, Milne RL, Muir K, Nathanson KL, Nuñez-Torres R, Obi N, Olson JE, Palmer JR, Panayiotidis MI, Patel AV, Pharoah PDP, Polley EC, Rashid MU, Ruddy KJ, Saloustros E, Sawyer EJ, Schmidt MK, Southey MC, Tan VK, Teo SH, Teras LR, Torres D, Trentham-Dietz A, Truong T, Vachon CM, Wang Q, Weitzel JN, Yadav S, Yao S, Zirpoli GR, Cline MS, Devilee P, Tavtigian SV, Goldgar DE, Couc… See abstract for full author list ➔ Zanti M, et al. Nat Commun. 2025 May 25;16(1):4852. doi: 10.1038/s41467-025-59979-6. Nat Commun. 2025. PMID: 40413188 Free PMC article.
Loss of SMARCA4 Leads to Intron Retention and Generation of Tumor-Associated Antigens in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.
Raupach EA, Hegde AM, Garcia-Mansfield K, Alcantara M, Rose DL, Halperin RF, Orlando KA, Lang JD, Sharma R, David-Dirgo V, Facista SJ, Moore R, Kofman R, Jensen ZN, Zismann VL, Karnezis AN, Wang Y, Bennett LB, Whitsett TG, Kortylewski M, Hendricks WPD, Huntsman DG, Rodriguez-Rodriguez L, Weissman BE, Trent JM, Pirrotte P. Raupach EA, et al. Cancer Res. 2025 Jul 15;85(14):2626-2642. doi: 10.1158/0008-5472.CAN-24-0044. Cancer Res. 2025. PMID: 40407709 Free PMC article.
Alcohol intake and pancreatic cancer risk: An analysis from 30 prospective studies across Asia, Australia, Europe, and North America.
Naudin S, Wang M, Dimou N, Ebrahimi E, Genkinger J, Adami HO, Albanes D, Babic A, Barnett M, Bogumil D, Cai H, Chen C, Eliassen AH, Freudenheim JL, Gierach G, Giovannucci EL, Gunter MJ, Håkansson N, Hirabayashi M, Hou T, Huang BZ, Huang WY, Jayasekara H, Jones ME, Katzke VA, Koh WP, Lacey JV, Lagerros YT, Larsson SC, Liao LM, Lo K, Loftfield E, MacInnis RJ, Männistö S, McCullough ML, Miller A, Milne RL, Moore SC, Mucci LA, Neuhouser ML, Patel AV, Platz EA, Prizment A, Robien K, Rohan TE, Sacerdote C, Sandin S, Sawada N, Schoemaker M, Shu XO, Sinha R, Snetselaar L, Stampfer MJ, Stolzenberg-Solomon R, Thomson CA, Tjønneland A, Um CY, van den Brandt PA, Visvanathan K, Wang SS, Wang R, Weiderpass E, Weinstein SJ, White E, Willett W, Woslk A, Wolpin BM, Yaun SS, Yuan C, Yuan JM, Zheng W, Brennan P, Smith-Warner SA, Ferrari P. Naudin S, et al. PLoS Med. 2025 May 20;22(5):e1004590. doi: 10.1371/journal.pmed.1004590. eCollection 2025 May. PLoS Med. 2025. PMID: 40392909 Free PMC article.
DNA2 and MSH2 activity collectively mediate chemically stabilized G4 for efficient telomere replication.
Fernandez A, Zhou T, Esworthy S, Shen C, Liu H, Hess JD, Yuan H, Liu N, Shi G, Zhou M, Kosiyatrakul S, Gaur V, Sommers J, Edelman W, Li GM, Brosh R, Chai W, Lee MYWT, Zhang D, Schildkraut C, Zheng L, Shen B. Fernandez A, et al. bioRxiv [Preprint]. 2025 Apr 6:2025.04.04.647332. doi: 10.1101/2025.04.04.647332. bioRxiv. 2025. PMID: 40330857 Free PMC article. Preprint.
Distinct adipose progenitor cells emerging with age drive active adipogenesis.
Wang G, Li G, Song A, Zhao Y, Yu J, Wang Y, Dai W, Salas M, Qin H, Medrano L, Dow J, Li A, Armstrong B, Fueger PT, Yu H, Zhu Y, Shao M, Wu X, Jiang L, Campisi J, Yang X, Wang QA. Wang G, et al. Science. 2025 Apr 25;388(6745):eadj0430. doi: 10.1126/science.adj0430. Epub 2025 Apr 25. Science. 2025. PMID: 40273250 Free PMC article.
Identification of CD84 as a potent survival factor in acute myeloid leukemia.
Zhu Y, Murtadha M, Liu M, Caserta E, Napolitano O, Nguyen LXT, Wang H, Moloudizargari M, Nigam L, Tandoh T, Wang X, Pozhitkov A, Su R, Lin X, Estepa MD, Pillai R, Song J, Sanchez JF, Fu YH, Zhang L, Li M, Zhang B, Li L, Kuo YH, Rosen S, Marcucci G, Williams JC, Pichiorri F. Zhu Y, et al. J Clin Invest. 2025 Apr 8;135(11):e176818. doi: 10.1172/JCI176818. eCollection 2025 Jun 2. J Clin Invest. 2025. PMID: 40198133 Free PMC article.
Assessment of MYC Gene and WNT Pathway Alterations in Early-Onset Colorectal Cancer Among Hispanic/Latino Patients Using Integrated Multi-Omics Approaches.
Carranza FG, Waldrup B, Jin Y, Amzaleg Y, Postel M, Craig DW, Carpten JD, Salhia B, Hernandez D, Gutierrez N, Ricker CN, Culver JO, Chavez CE, Stern MC, Baezconde-Garbanati L, Lenz HJ, Velazquez-Villarreal E. Carranza FG, et al. medRxiv [Preprint]. 2025 Feb 22:2024.12.05.24318588. doi: 10.1101/2024.12.05.24318588. medRxiv. 2025. PMID: 40034762 Free PMC article. Preprint.
Gene expression associated with endocrine therapy resistance in estrogen receptor-positive breast cancer.
Jones V, Yin HH, Yuan YC, Wang Y, Li SM, Aljaber D, Sanchez A, Quinones C, Schmolze D, Yuan Y, Mortimer J, Yee L, Kruper L, Jovanovic-Talisman T, Tomsic J, Sanchez N, Chavez T, O'Regan RM, Khan QJ, Davis M, Kalinsky K, Meisel J, Kittles R, Rodriguez-Rodriguez L, Seewaldt V. Jones V, et al. Sci Rep. 2025 Feb 28;15(1):7220. doi: 10.1038/s41598-025-89274-9. Sci Rep. 2025. PMID: 40021703 Free PMC article.
SARS-CoV-2 infectivity can be modulated through bacterial grooming of the glycocalyx.
Martino C, Kellman BP, Sandoval DR, Clausen TM, Cooper R, Benjdia A, Soualmia F, Clark AE, Garretson AF, Marotz CA, Song SJ, Wandro S, Zaramela LS, Salido RA, Zhu Q, Armingol E, Vázquez-Baeza Y, McDonald D, Sorrentino JT, Taylor B, Belda-Ferre P, Das P, Ali F, Liang C, Zhang Y, Schifanella L, Covizzi A, Lai A, Riva A, Basting C, Broedlow CA, Havulinna AS, Jousilahti P, Estaki M, Kosciolek T, Kuplicki R, Victor TA, Paulus MP, Savage KE, Benbow JL, Spielfogel ES, Anderson CAM, Martinez ME, Lacey JV Jr, Huang S, Haiminen N, Parida L, Kim H-C, Gilbert JA, Sweeney DA, Allard SM, Swafford AD, Cheng S, Inouye M, Niiranen T, Jain M, Salomaa V, Zengler K, Klatt NR, Hasty J, Berteau O, Carlin AF, Esko JD, Lewis NE, Knight R. Martino C, et al. mBio. 2025 Apr 9;16(4):e0401524. doi: 10.1128/mbio.04015-24. Epub 2025 Feb 25. mBio. 2025. PMID: 39998226 Free PMC article.
miR-142 deficit in T cells during blast crisis promotes chronic myeloid leukemia immune escape.
Chen F, Zhao D, Xu Y, Zhang Y, Chen MH, Pathak KV, Hansen N, Lovell B, Liang Y, Estrella K, Wang WL, Ghoda L, Rockne R, Wu X, Ali H, Yu J, Caligiuri MA, Forman SJ, Trent JM, Kuo YH, Li L, Swiderski P, Zhang J, Kortylewski M, Nguyen LXT, Pirrotte P, Boldin M, Marcucci G, Zhang B. Chen F, et al. Nat Commun. 2025 Feb 1;16(1):1253. doi: 10.1038/s41467-025-56383-y. Nat Commun. 2025. PMID: 39893171 Free PMC article.
CAMKIIδ Reinforces Lipid Metabolism and Promotes the Development of B Cell Lymphoma.
Zhang J, Xu S, Fang H, Wu D, Ouyang C, Shi Y, Hu Z, Zhang M, Zhong Y, Zhao J, Gan Y, Zhang S, Liu X, Yin J, Li Y, Tang M, Wang Y, Li L, Chan WC, Horne D, Feng M, Huang W, Gu Y. Zhang J, et al. Adv Sci (Weinh). 2025 Mar;12(10):e2409513. doi: 10.1002/advs.202409513. Epub 2025 Jan 22. Adv Sci (Weinh). 2025. PMID: 39840457 Free PMC article.
Validation of Clinical Dynamic Contrast-Enhanced Magnetic Resonance Imaging Perfusion Modeling and Neoadjuvant Chemotherapy Response Prediction in Breast Cancer Using 18FDG and 64Cu-DOTA-Trastuzumab Positron Emission Tomography Studies.
Whitman J, Adhikarla V, Tumyan L, Mortimer J, Huang W, Rockne R, Peterson JR, Cole J. Whitman J, et al. JCO Clin Cancer Inform. 2025 Jan;9:e2300248. doi: 10.1200/CCI.23.00248. Epub 2025 Jan 14. JCO Clin Cancer Inform. 2025. PMID: 39808751
LGR4 is essential for maintaining β-cell homeostasis through suppression of RANK.
Filipowska J, Cisneros Z, Varghese SS, Leon-Rivera N, Wang P, Kang R, Lu G, Yuan YC, Shih HP, Bhattacharya S, Dhawan S, Garcia-Ocaña A, Kondegowda NG, Vasavada RC. Filipowska J, et al. Mol Metab. 2025 Feb;92:102097. doi: 10.1016/j.molmet.2025.102097. Epub 2025 Jan 7. Mol Metab. 2025. PMID: 39788290 Free PMC article.
Multi-omics analysis of long-term cultured human islets.
Sun G, Qi M, Sun O, Lizhar EM, Hussey D, Shi Y, Riggs AD. Sun G, et al. bioRxiv [Preprint]. 2024 Dec 25:2024.12.25.626491. doi: 10.1101/2024.12.25.626491. bioRxiv. 2024. PMID: 39763987 Free PMC article. Preprint.
Glycerol-3-phosphate activates ChREBP, FGF21 transcription and lipogenesis in Citrin Deficiency.
Tiwari V, Jin B, Sun O, Lopez Gonzalez EDJ, Chen MH, Wu X, Shah H, Zhang A, Herman MA, Spracklen CN, Goodman RP, Brenner C. Tiwari V, et al. bioRxiv [Preprint]. 2025 Jun 25:2024.12.27.630525. doi: 10.1101/2024.12.27.630525. bioRxiv. 2025. Update in: Nat Metab. 2025 Nov;7(11):2284-2299. doi: 10.1038/s42255-025-01399-3. PMID: 39763913 Free PMC article. Updated. Preprint.
Nuclear Control of Mitochondrial Homeostasis and Venetoclax Efficacy in AML via COX4I1.
Zhang L, Zhang H, Wang TY, Li M, Chan AKN, Kang H, Foong LC, Liu Q, Pokharel SP, Mattson NM, Singh P, Elsayed Z, Kuang B, Wang X, Rosen ST, Chen J, Yang L, Chou TF, Su R, Chen CD. Zhang L, et al. Adv Sci (Weinh). 2025 Feb;12(6):e2404620. doi: 10.1002/advs.202404620. Epub 2024 Dec 23. Adv Sci (Weinh). 2025. PMID: 39716856 Free PMC article.
Fludarabine melphalan reduced intensity conditioning vs radiation-based myeloablative conditioning in patients undergoing allogeneic transplantation for acute myeloid leukemia with measurable residual disease.
Blackmon A, Afkhami M, Yang D, Mokhtari S, Samara Y, Pourhassan H, Ball B, Salhotra A, Agrawal V, Sandhu K, Desai A, Otoukesh S, Arslan S, Amanam I, Koller P, Tinajero J, Aribi A, Aldoss I, Becker P, Artz A, Ali H, Stein A, Smith E, Pullarkat V, Forman SJ, Marcucci G, Nakamura R, Al Malki MM. Blackmon A, et al. Bone Marrow Transplant. 2025 Feb;60(2):165-174. doi: 10.1038/s41409-024-02491-0. Epub 2024 Dec 18. Bone Marrow Transplant. 2025. PMID: 39695333 Free PMC article.
YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies.
Chen Z, Zeng C, Yang L, Che Y, Chen M, Sau L, Wang B, Zhou K, Chen Y, Qing Y, Shen C, Zhang T, Wunderlich M, Wu D, Li W, Wang K, Leung K, Sun M, Tang T, He X, Zhang L, Swaminathan S, Mulloy JC, Müschen M, Huang H, Weng H, Xiao G, Deng X, Chen J. Chen Z, et al. Cell. 2025 Jan 23;188(2):331-351.e30. doi: 10.1016/j.cell.2024.11.007. Epub 2024 Dec 17. Cell. 2025. PMID: 39694037
Reducing learning and psychosocial disparities in Latino children with cancer: a randomized intervention trial.
Patel SK, Kim SH, Ingman K, Huynh V, Huszti H, Kayser K, Mucci G, Balderrama M, Bava L, Onderwyzer Gold A, Wuth A, Delgado N, Bosworth A, Nishimura E, Hara H, Pawlowska A, Mueller L, Wong FL. Patel SK, et al. J Natl Cancer Inst. 2025 Mar 1;117(3):465-475. doi: 10.1093/jnci/djae256. J Natl Cancer Inst. 2025. PMID: 39412495 Free PMC article. Clinical Trial.
Cardiomyocyte-derived circulating extracellular vesicles allow a non-invasive liquid biopsy of myocardium in health and disease.
Spanos M, Gokulnath P, Li G, Hutchins E, Meechoovet B, Sheng Q, Chatterjee E, Sharma R, Carnel-Amar N, Lin C, Azzam C, Ghaeli I, Amancherla KV, Victorino JF, Garcia-Mansfield K, Pfeffer R, Sahu P, Lindman BR, Elmariah S, Gamazon ER, Betti MJ, Bledsoe X, Lance ML, Absi T, Su YR, Do N, Contreras MG, Varrias D, Kladas M, Radulovic M, Tsiachris D, Spanos A, Tsioufis K, Ellinor PT, Tucker NR, Januzzi JL, Pirrotte P, Jovanovic-Talisman T, Van Keuren-Jensen K, Shah R, Das S. Spanos M, et al. medRxiv [Preprint]. 2024 Sep 22:2024.09.19.24314009. doi: 10.1101/2024.09.19.24314009. medRxiv. 2024. PMID: 39371135 Free PMC article. Preprint.
A Multicenter Analysis of Allogeneic Transplant Outcomes in Adults with Philadelphia-Like B-Cell Acute Lymphoblastic Leukemia in First Complete Remission.
Rahman ZA, Othman T, Saliba RM, Vanegas YAM, Mohty R, Ledesma C, Rondon G, Jain N, Jabbour E, Pullarkat V, Alkhateeb HB, Kantarjian HM, Greipp PT, Nakamura R, Kharfan-Dabaja MA, Champlin RE, Forman SJ, Shpall EJ, Litzow MR, Foran JM, Aldoss I, Koller PB, Kebriaei P. Rahman ZA, et al. Transplant Cell Ther. 2024 Dec;30(12):1197-1205. doi: 10.1016/j.jtct.2024.09.020. Epub 2024 Sep 26. Transplant Cell Ther. 2024. PMID: 39332807 Free article.
Associations between per- and poly-fluoroalkyl substance (PFAS) exposure and immune responses among women in the California Teachers study: A cross-sectional evaluation.
Cauble EL, Reynolds P, Epeldegui M, Andra SS, Magpantay L, Narasimhan S, Pulivarthi D, Von Behren J, Martinez-Maza O, Goldberg D, Spielfogel ES, Lacey JV Jr, Wang SS. Cauble EL, et al. Cytokine. 2024 Dec;184:156753. doi: 10.1016/j.cyto.2024.156753. Epub 2024 Sep 18. Cytokine. 2024. PMID: 39299102 Free PMC article.
Bi-functional CpG-STAT3 decoy oligonucleotide triggers multilineage differentiation of acute myeloid leukemia in mice.
Wang D, Kaniowski D, Jacek K, Su YL, Yu C, Hall J, Li H, Feng M, Hui S, Kaminska B, DeFranciscis V, Esposito CL, DiRuscio A, Zhang B, Marcucci G, Kuo YH, Kortylewski M. Wang D, et al. Mol Ther Nucleic Acids. 2024 Jul 16;35(3):102268. doi: 10.1016/j.omtn.2024.102268. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 39171140 Free PMC article.
Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) experience in patients with recurrent low grade serous ovarian carcinoma (LGSOC): sub-cohort report of phase 1 clinical trial.
Nakamura B, Senguttuvan R, Ruel NH, Frankel PH, Yost SE, Cole S, Chang S, Jung A, Eng M, Tinsley R, Stewart D, Wang E, Cohen J, Villella J, Whelan RL, Merchea A, DePeralta DK, Cristea M, Wakabayashi MT, Raoof M, Dellinger TH. Nakamura B, et al. Front Oncol. 2024 Aug 1;14:1404936. doi: 10.3389/fonc.2024.1404936. eCollection 2024. Front Oncol. 2024. PMID: 39148906 Free PMC article.
Comparing transplant outcomes in ALL patients after myeloablative conditioning in mismatch-related or unrelated donor settings.
Otoukesh S, Yang D, Mokhtari S, Pourhassan H, Agrawal V, Arslan S, Amanam I, Ball B, Koller P, Salhotra A, Sandhu K, Aribi A, Artz A, Aldoss I, Pullarkat V, Ali H, Blackmon A, Becker P, Curtin P, Stewart F, Smith E, Stein A, Marcucci G, Forman SJ, Nakamura R, Al Malki MM. Otoukesh S, et al. Bone Marrow Transplant. 2024 Nov;59(11):1542-1551. doi: 10.1038/s41409-024-02378-0. Epub 2024 Aug 15. Bone Marrow Transplant. 2024. PMID: 39147891 Free PMC article.
IL1RAP-specific T cell engager depletes acute myeloid leukemia stem cells.
Zhang Y, Park M, Ghoda LY, Zhao D, Valerio M, Nafie E, Gonzalez A, Ly K, Parcutela B, Choi H, Gong X, Chen F, Harada K, Chen Z, Nguyen LXT, Pichiorri F, Chen J, Song J, Forman SJ, Amanam I, Zhang B, Jin J, Williams JC, Marcucci G. Zhang Y, et al. J Hematol Oncol. 2024 Aug 14;17(1):67. doi: 10.1186/s13045-024-01586-x. J Hematol Oncol. 2024. PMID: 39143574 Free PMC article.
Personalized neoantigen vaccines as early intervention in untreated patients with lymphoplasmacytic lymphoma: a non-randomized phase 1 trial.
Szymura SJ, Wang L, Zhang T, Cha SC, Song J, Dong Z, Anderson A, Oh E, Lee V, Wang Z, Parshottam S, Rao S, Olsem JB, Crumpton BN, Lee HC, Manasanch EE, Neelapu S, Kwak LW, Thomas SK. Szymura SJ, et al. Nat Commun. 2024 Aug 11;15(1):6874. doi: 10.1038/s41467-024-50880-2. Nat Commun. 2024. PMID: 39128904 Free PMC article. Clinical Trial.
Phenotypic Plasticity and Cancer: A System Biology Perspective.
Subbalakshmi AR, Ramisetty S, Mohanty A, Pareek S, Do D, Shrestha S, Khan A, Talwar N, Tan T, Vishnubhotla P, Singhal SS, Salgia R, Kulkarni P. Subbalakshmi AR, et al. J Clin Med. 2024 Jul 23;13(15):4302. doi: 10.3390/jcm13154302. J Clin Med. 2024. PMID: 39124569 Free PMC article. Review.
Insulin Resistance in Women Correlates with Chromatin Histone Lysine Acetylation, Inflammatory Signaling, and Accelerated Aging.
Vidal CM, Alva-Ornelas JA, Chen NZ, Senapati P, Tomsic J, Robles VM, Resto C, Sanchez N, Sanchez A, Hyslop T, Emwas N, Aljaber D, Bachelder N, Martinez E, Ann D, Jones V, Winn RA, Miele L, Ochoa AC, Dietze EC, Natarajan R, Schones D, Seewaldt VL. Vidal CM, et al. Cancers (Basel). 2024 Aug 1;16(15):2735. doi: 10.3390/cancers16152735. Cancers (Basel). 2024. PMID: 39123463 Free PMC article.
Total Body Irradiation and Fludarabine with Post-Transplantation Cyclophosphamide for Mismatched Related or Unrelated Donor Hematopoietic Cell Transplantation.
Arslan S, Desai A, Yang D, Mokhtari S, Tiemann K, Otoukesh S, Samara Y, Blackmon A, Agrawal V, Pourhassan H, Amanam I, Ball B, Koller P, Salhotra A, Aribi A, Becker P, Curtin P, Artz A, Aldoss I, Ali H, Stewart F, Smith E, Stein A, Marcucci G, Forman SJ, Nakamura R, Al Malki MM. Arslan S, et al. Transplant Cell Ther. 2024 Oct;30(10):1013.e1-1013.e12. doi: 10.1016/j.jtct.2024.08.005. Epub 2024 Aug 8. Transplant Cell Ther. 2024. PMID: 39122188 Free PMC article.
MGA deletion leads to Richter's transformation by modulating mitochondrial OXPHOS.
Iyer P, Zhang B, Liu T, Jin M, Hart K, Zhang J, Siegert V, Remke M, Wang X, Yu L, Song J, Venkataraman G, Chan WC, Jia Z, Buchner M, Siddiqi T, Rosen ST, Danilov A, Wang L. Iyer P, et al. Sci Transl Med. 2024 Jul 31;16(758):eadg7915. doi: 10.1126/scitranslmed.adg7915. Epub 2024 Jul 31. Sci Transl Med. 2024. PMID: 39083585 Free PMC article.
Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC.
Mirzapoiazova T, Tseng L, Mambetsariev B, Li H, Lou CH, Pozhitkov A, Ramisetty SK, Nam S, Mambetsariev I, Armstrong B, Malhotra J, Arvanitis L, Nasser MW, Batra SK, Rosen ST, Wheeler DL, Singhal SS, Kulkarni P, Salgia R. Mirzapoiazova T, et al. iScience. 2024 May 27;27(6):110132. doi: 10.1016/j.isci.2024.110132. eCollection 2024 Jun 21. iScience. 2024. PMID: 38993482 Free PMC article.
Spatial iTME analysis of KRAS mutant NSCLC and immunotherapy outcome.
Zhao D, Li H, Mambetsariev I, Mirzapoiazova T, Chen C, Fricke J, Wheeler D, Arvanitis L, Pillai R, Afkhami M, Chen BT, Sattler M, Erhunmwunsee L, Massarelli E, Kulkarni P, Amini A, Armstrong B, Salgia R. Zhao D, et al. NPJ Precis Oncol. 2024 Jun 19;8(1):135. doi: 10.1038/s41698-024-00626-6. NPJ Precis Oncol. 2024. PMID: 38898200 Free PMC article.
PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer: a phase 1 trial.
Dorff TB, Blanchard MS, Adkins LN, Luebbert L, Leggett N, Shishido SN, Macias A, Del Real MM, Dhapola G, Egelston C, Murad JP, Rosa R, Paul J, Chaudhry A, Martirosyan H, Gerdts E, Wagner JR, Stiller T, Tilakawardane D, Pal S, Martinez C, Reiter RE, Budde LE, D'Apuzzo M, Kuhn P, Pachter L, Forman SJ, Priceman SJ. Dorff TB, et al. Nat Med. 2024 Jun;30(6):1636-1644. doi: 10.1038/s41591-024-02979-8. Epub 2024 Jun 12. Nat Med. 2024. PMID: 38867077 Free PMC article. Clinical Trial.
Palbociclib in adults aged 70 years and older with advanced breast cancer: A phase 2 multicenter trial (Alliance A171601).
Sedrak MS, Lee MK, Ji J, Satele DV, Freedman RA, Poorvu PD, O'Connor T, Williams GR, Hopkins JO, Muss HB, Cohen HJ, Partridge AH, Carey LA, Chow SL, Subbiah N, Le-Rademacher J, Jatoi A. Sedrak MS, et al. J Geriatr Oncol. 2024 Jul;15(6):101813. doi: 10.1016/j.jgo.2024.101813. Epub 2024 Jun 8. J Geriatr Oncol. 2024. PMID: 38852379 Free PMC article. Clinical Trial.
Yttrium-90 anti-CD25 BEAM conditioning for autologous hematopoietic cell transplantation in Peripheral T-cell lymphoma.
Zain J, Tsai NC, Palmer J, Simpson J, Adhikarla V, Bading JR, Yazaki P, Smith EP, Dandapani S, Song JY, Karras NA, Herrera AF, Salhotra A, Nademanee AP, Nakamura R, Smith DL, Yamauchi D, Poku EK, Biglang-Awa VE, Colcher D, Shively JE, Wu AM, Forman SJ, Wong J, Thomas S. Zain J, et al. Blood Adv. 2024 Sep 24;8(18):4812-4822. doi: 10.1182/bloodadvances.2023012497. Blood Adv. 2024. PMID: 38838232 Free PMC article. Clinical Trial.
Association of ESR1 Germline Variants with TP53 Somatic Variants in Breast Tumors in a Genome-wide Study.
Tjader NP, Beer AJ, Ramroop J, Tai MC, Ping J, Gandhi T, Dauch C, Neuhausen SL, Ziv E, Sotelo N, Ghanekar S, Meadows O, Paredes M, Gillespie JL, Aeilts AM, Hampel H, Zheng W, Jia G, Hu Q, Wei L, Liu S, Ambrosone CB, Palmer JR, Carpten JD, Yao S, Stevens P, Ho WK, Pan JW, Fadda P, Huo D, Teo SH, McElroy JP, Toland AE. Tjader NP, et al. Cancer Res Commun. 2024 Jun 27;4(6):1597-1608. doi: 10.1158/2767-9764.CRC-24-0026. Cancer Res Commun. 2024. PMID: 38836758 Free PMC article.
Integrated analysis of blood DNA methylation, genetic variants, circulating proteins, microRNAs, and kidney failure in type 1 diabetes.
Chen Z, Satake E, Pezzolesi MG, Md Dom ZI, Stucki D, Kobayashi H, Syreeni A, Johnson AT, Wu X, Dahlström EH, King JB, Groop PH, Rich SS, Sandholm N, Krolewski AS, Natarajan R. Chen Z, et al. Sci Transl Med. 2024 May 22;16(748):eadj3385. doi: 10.1126/scitranslmed.adj3385. Epub 2024 May 22. Sci Transl Med. 2024. PMID: 38776390 Free PMC article.
Hypertension and Risk of Endometrial Cancer: A Pooled Analysis in the Epidemiology of Endometrial Cancer Consortium (E2C2).
Habeshian TS, Peeri NC, De Vivo I, Schouten LJ, Shu XO, Cote ML, Bertrand KA, Chen Y, Clarke MA, Clendenen TV, Cook LS, Costas L, Dal Maso L, Freudenheim JL, Friedenreich CM, Gallagher G, Gierach GL, Goodman MT, Jordan SJ, La Vecchia C, Lacey JV, Levi F, Liao LM, Lipworth L, Lu L, Matias-Guiu X, Moysich KB, Mutter GL, Na R, Naduparambil J, Negri E, O'Connell K, O'Mara TA, Onieva Hernández I, Palmer JR, Parazzini F, Patel AV, Penney KL, Prizment AE, Ricceri F, Risch HA, Sacerdote C, Sandin S, Stolzenberg-Solomon RZ, van den Brandt PA, Webb PM, Wentzensen N, Wijayabahu AT, Wilkens LR, Xu W, Yu H, Zeleniuch-Jacquotte A, Zheng W, Du M, Setiawan VW. Habeshian TS, et al. Cancer Epidemiol Biomarkers Prev. 2024 Jun 3;33(6):788-795. doi: 10.1158/1055-9965.EPI-23-1444. Cancer Epidemiol Biomarkers Prev. 2024. PMID: 38530242 Free PMC article.
Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial.
Brown CE, Hibbard JC, Alizadeh D, Blanchard MS, Natri HM, Wang D, Ostberg JR, Aguilar B, Wagner JR, Paul JA, Starr R, Wong RA, Chen W, Shulkin N, Aftabizadeh M, Filippov A, Chaudhry A, Ressler JA, Kilpatrick J, Myers-McNamara P, Chen M, Wang LD, Rockne RC, Georges J, Portnow J, Barish ME, D'Apuzzo M, Banovich NE, Forman SJ, Badie B. Brown CE, et al. Nat Med. 2024 Apr;30(4):1001-1012. doi: 10.1038/s41591-024-02875-1. Epub 2024 Mar 7. Nat Med. 2024. PMID: 38454126 Free PMC article. Clinical Trial.
Targeting Wnt signaling for improved glioma immunotherapy.
Gutova M, Hibbard JC, Ma E, Natri HM, Adhikarla V, Chimge NO, Qiu R, Nguyen C, Melendez E, Aguilar B, Starr R, Yin H, Rockne RC, Ono M, Banovich NE, Yuan YC, Brown CE, Kahn M. Gutova M, et al. Front Immunol. 2024 Feb 21;15:1342625. doi: 10.3389/fimmu.2024.1342625. eCollection 2024. Front Immunol. 2024. PMID: 38449858 Free PMC article.
Cytomegalovirus Triplex vaccine in pediatric hematopoietic stem cell transplant patients at high risk for cytomegalovirus complications: evaluation of vaccine safety, immunogenicity and impact on viremia requiring antivirals.
La Rosa C, Park Y, Yang D, Zhou Q, Kaltcheva T, Karras N, Cheng J, Sun W, Diamond DJ, Pawlowska A. La Rosa C, et al. Haematologica. 2024 Jul 1;109(7):2303-2308. doi: 10.3324/haematol.2023.284256. Haematologica. 2024. PMID: 38426277 Free PMC article. No abstract available.
Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity.
Dong H, He X, Zhang L, Chen W, Lin YC, Liu SB, Wang H, Nguyen LXT, Li M, Zhu Y, Zhao D, Ghoda L, Serody J, Vincent B, Luznik L, Gojo I, Zeidner J, Su R, Chen J, Sharma R, Pirrotte P, Wu X, Hu W, Han W, Shen B, Kuo YH, Jin J, Salhotra A, Wang J, Marcucci G, Luo YL, Li L. Dong H, et al. Nat Cancer. 2024 Apr;5(4):601-624. doi: 10.1038/s43018-024-00736-x. Epub 2024 Feb 27. Nat Cancer. 2024. PMID: 38413714 Free PMC article.
A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-γ-induced CD38 expression.
Murtadha M, Park M, Zhu Y, Caserta E, Napolitano O, Tandoh T, Moloudizargari M, Pozhitkov A, Singer M, Dona AA, Vahed H, Gonzalez A, Ly K, Ouyang C, Sanchez JF, Nigam L, Duplan A, Chowdhury A, Ghoda L, Li L, Zhang B, Krishnan A, Marcucci G, Williams JC, Pichiorri F. Murtadha M, et al. Blood. 2024 Apr 18;143(16):1599-1615. doi: 10.1182/blood.2023021570. Blood. 2024. PMID: 38394668 Free PMC article.
Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery.
Chan AKN, Han L, Delaney CD, Wang X, Mukhaleva E, Li M, Yang L, Pokharel SP, Mattson N, Garcia M, Wang B, Xu X, Zhang L, Singh P, Elsayed Z, Chen R, Kuang B, Wang J, Yuan YC, Chen B, Chan LN, Rosen ST, Horne D, Müschen M, Chen J, Vaidehi N, Armstrong SA, Su R, Chen CW. Chan AKN, et al. Sci Adv. 2024 Feb 23;10(8):eadk3127. doi: 10.1126/sciadv.adk3127. Epub 2024 Feb 23. Sci Adv. 2024. PMID: 38394203 Free PMC article.
SWOG S1820: A pilot randomized trial of the Altering Intake, Managing Bowel Symptoms Intervention in Survivors of Rectal Cancer.
Sun V, Guthrie KA, Crane TE, Arnold KB, Colby S, Freylersythe SG, Braun-Inglis C, Topacio R, Messick CA, Carmichael JC, Muskovitz AA, Nashawaty M, Bajaj M, Cohen SA, Flaherty DC, O'Rourke MA, Jones L, Krouse RS, Thomson CA. Sun V, et al. Cancer. 2024 Jul 1;130(13):2384-2394. doi: 10.1002/cncr.35264. Epub 2024 Feb 22. Cancer. 2024. PMID: 38386696 Free PMC article. Clinical Trial.
HIV-1 Remission after Allogeneic Hematopoietic-Cell Transplantation.
Dickter JK, Aribi A, Cardoso AA, Gianella S, Gendzekhadze K, Li S, Feng Y, Chaillon A, Laird GM, Browning DL, Ross JA, Nanayakkara DD, Puing A, Stan R, Lai LL, Chang S, Kidambi TD, Thomas S, Al Malki MM, Nakamura R, Alvarnas J, Taplitz RA, Dadwal SS, Forman SJ, Zaia JA. Dickter JK, et al. N Engl J Med. 2024 Feb 15;390(7):669-671. doi: 10.1056/NEJMc2312556. N Engl J Med. 2024. PMID: 38354149 Free PMC article. No abstract available.
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens.
Mattson NM, Chan AKN, Miyashita K, Mukhaleva E, Chang WH, Yang L, Ma N, Wang Y, Pokharel SP, Li M, Liu Q, Xu X, Chen R, Singh P, Zhang L, Elsayed Z, Chen B, Keen D, Pirrotte P, Rosen ST, Chen J, LaBarge MA, Shively JE, Vaidehi N, Rockne RC, Feng M, Chen CW. Mattson NM, et al. Nat Struct Mol Biol. 2024 Mar;31(3):465-475. doi: 10.1038/s41594-024-01211-y. Epub 2024 Feb 5. Nat Struct Mol Biol. 2024. PMID: 38316881 Free PMC article.
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