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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 1
2007 1
2008 5
2009 5
2010 8
2011 6
2012 4
2013 15
2014 11
2015 21
2016 9
2018 3
2019 2
2020 1
2021 1
2022 3
2023 2
2024 5
2025 1
2026 1

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92 results

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Page 1
Pediatric H3 G34-mutant diffuse hemispheric glioma: clinical, imaging and molecular prognostic factors, MGMT expression, and temozolomide response.
Tlais D, Zhang Q, Roach JT, Tinkle CL, Lin T, Li X, Mostafa A, Moreira DC, McNall-Knapp RY, Rush SZ, Le BH, Sinno S, Ramnarayan A, Ginn KF, Partap S, Onar-Thomas A, Furtado LV, Bag AK, Chiang J. Tlais D, et al. Acta Neuropathol. 2026 Mar 2;151(1):22. doi: 10.1007/s00401-026-02992-w. Acta Neuropathol. 2026. PMID: 41770225 Free PMC article.
Comprehensive analysis of MYB/MYBL1-altered pediatric-type diffuse low-grade glioma.
Moreira DC, Qaddoumi I, Spiller S, Bouldin TW, Davidson A, Saba-Silva N, Sullivan DV, Tanaka R, Wagner AS, Wood M, Klimo P, Job G, Devidas M, Li X, Gajjar A, Robinson GW, Chiang J. Moreira DC, et al. Neuro Oncol. 2024 Jul 5;26(7):1327-1334. doi: 10.1093/neuonc/noae048. Neuro Oncol. 2024. PMID: 38466086 Free PMC article.
High-grade glioma in infants and young children is histologically, molecularly, and clinically diverse: Results from the SJYC07 trial and institutional experience.
Chiang J, Bagchi A, Li X, Dhanda SK, Huang J, Pinto SN, Sioson E, Dalton J, Tatevossian RG, Jia S, Partap S, Fisher PG, Bowers DC, Hassall TEG, Lu C, Zaldivar-Peraza A, Wright KD, Broniscer A, Qaddoumi I, Upadhyaya SA, Vinitsky A, Sabin ND, Orr BA, Klimo P Jr, Boop FA, Ashford JM, Conklin HM, Onar-Thomas A, Zhou X, Ellison DW, Gajjar A, Robinson GW. Chiang J, et al. Neuro Oncol. 2024 Jan 5;26(1):178-190. doi: 10.1093/neuonc/noad130. Neuro Oncol. 2024. PMID: 37503880 Free PMC article.
Lorlatinib in a Child with ALK-Fusion-Positive High-Grade Glioma.
Bagchi A, Orr BA, Campagne O, Dhanda S, Nair S, Tran Q, Christensen AM, Gajjar A, Furtado LV, Vasilyeva A, Boop F, Stewart C, Robinson GW. Bagchi A, et al. N Engl J Med. 2021 Aug 19;385(8):761-763. doi: 10.1056/NEJMc2101264. N Engl J Med. 2021. PMID: 34407349 Free PMC article. No abstract available.
Correction to: H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.
Silveira AB, Kasper LH, Fan Y, Jin H, Wu G, Shaw TI, Zhu X, Larson JD, Easton J, Shao Y, Yergeau DA, Rosencrance C, Boggs K, Rusch MC, Ding L, Zhang J, Finkelstein D, Noyes RM, Russell BL, Xu B, Broniscer A, Wetmore C, Pounds SB, Ellison DW, Zhang J, Baker SJ. Silveira AB, et al. Acta Neuropathol. 2019 Jun;137(6):1021. doi: 10.1007/s00401-019-02006-y. Epub 2019 Apr 11. Acta Neuropathol. 2019. PMID: 30976974 Free PMC article.
Structure and evolution of double minutes in diagnosis and relapse brain tumors.
Xu K, Ding L, Chang TC, Shao Y, Chiang J, Mulder H, Wang S, Shaw TI, Wen J, Hover L, McLeod C, Wang YD, Easton J, Rusch M, Dalton J, Downing JR, Ellison DW, Zhang J, Baker SJ, Wu G. Xu K, et al. Acta Neuropathol. 2019 Jan;137(1):123-137. doi: 10.1007/s00401-018-1912-1. Epub 2018 Sep 28. Acta Neuropathol. 2019. PMID: 30267146 Free PMC article.
Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype.
Phoenix TN, Patmore DM, Boop S, Boulos N, Jacus MO, Patel YT, Roussel MF, Finkelstein D, Goumnerova L, Perreault S, Wadhwa E, Cho YJ, Stewart CF, Gilbertson RJ. Phoenix TN, et al. Cancer Cell. 2016 Apr 11;29(4):508-522. doi: 10.1016/j.ccell.2016.03.002. Epub 2016 Mar 31. Cancer Cell. 2016. PMID: 27050100 Free PMC article.
A phosphotyrosine switch regulates organic cation transporters.
Sprowl JA, Ong SS, Gibson AA, Hu S, Du G, Lin W, Li L, Bharill S, Ness RA, Stecula A, Offer SM, Diasio RB, Nies AT, Schwab M, Cavaletti G, Schlatter E, Ciarimboli G, Schellens JHM, Isacoff EY, Sali A, Chen T, Baker SD, Sparreboom A, Pabla N. Sprowl JA, et al. Nat Commun. 2016 Mar 16;7:10880. doi: 10.1038/ncomms10880. Nat Commun. 2016. PMID: 26979622 Free PMC article.
System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Zhang W, Wu KP, Sartori MA, Kamadurai HB, Ordureau A, Jiang C, Mercredi PY, Murchie R, Hu J, Persaud A, Mukherjee M, Li N, Doye A, Walker JR, Sheng Y, Hao Z, Li Y, Brown KR, Lemichez E, Chen J, Tong Y, Harper JW, Moffat J, Rotin D, Schulman BA, Sidhu SS. Zhang W, et al. Mol Cell. 2016 Apr 7;62(1):121-36. doi: 10.1016/j.molcel.2016.02.005. Epub 2016 Mar 3. Mol Cell. 2016. PMID: 26949039 Free PMC article.
An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes.
Mohankumar KM, Currle DS, White E, Boulos N, Dapper J, Eden C, Nimmervoll B, Thiruvenkatam R, Connelly M, Kranenburg TA, Neale G, Olsen S, Wang YD, Finkelstein D, Wright K, Gupta K, Ellison DW, Thomas AO, Gilbertson RJ. Mohankumar KM, et al. Nat Genet. 2015 Aug;47(8):878-87. doi: 10.1038/ng.3323. Epub 2015 Jun 15. Nat Genet. 2015. PMID: 26075792 Free PMC article.
Quantitative protein analysis by mass spectrometry.
Pagala VR, High AA, Wang X, Tan H, Kodali K, Mishra A, Kavdia K, Xu Y, Wu Z, Peng J. Pagala VR, et al. Methods Mol Biol. 2015;1278:281-305. doi: 10.1007/978-1-4939-2425-7_17. Methods Mol Biol. 2015. PMID: 25859956
RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex.
Brown NG, VanderLinden R, Watson ER, Qiao R, Grace CR, Yamaguchi M, Weissmann F, Frye JJ, Dube P, Ei Cho S, Actis ML, Rodrigues P, Fujii N, Peters JM, Stark H, Schulman BA. Brown NG, et al. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5272-9. doi: 10.1073/pnas.1504161112. Epub 2015 Mar 30. Proc Natl Acad Sci U S A. 2015. PMID: 25825779 Free PMC article.
Protein neddylation: beyond cullin-RING ligases.
Enchev RI, Schulman BA, Peter M. Enchev RI, et al. Nat Rev Mol Cell Biol. 2015 Jan;16(1):30-44. doi: 10.1038/nrm3919. Nat Rev Mol Cell Biol. 2015. PMID: 25531226 Free PMC article. Review.
Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly.
Brown NG, Watson ER, Weissmann F, Jarvis MA, VanderLinden R, Grace CRR, Frye JJ, Qiao R, Dube P, Petzold G, Cho SE, Alsharif O, Bao J, Davidson IF, Zheng JJ, Nourse A, Kurinov I, Peters JM, Stark H, Schulman BA. Brown NG, et al. Mol Cell. 2014 Oct 23;56(2):246-260. doi: 10.1016/j.molcel.2014.09.009. Epub 2014 Oct 9. Mol Cell. 2014. PMID: 25306923 Free PMC article.
Influence of drug formulation on OATP1B-mediated transport of paclitaxel.
Nieuweboer AJ, Hu S, Gui C, Hagenbuch B, Ghobadi Moghaddam-Helmantel IM, Gibson AA, de Bruijn P, Mathijssen RH, Sparreboom A. Nieuweboer AJ, et al. Cancer Res. 2014 Jun 1;74(11):3137-45. doi: 10.1158/0008-5472.CAN-13-3634. Epub 2014 Apr 22. Cancer Res. 2014. PMID: 24755470 Free PMC article.
Orthotopic models of pediatric brain tumors in zebrafish.
Eden CJ, Ju B, Murugesan M, Phoenix TN, Nimmervoll B, Tong Y, Ellison DW, Finkelstein D, Wright K, Boulos N, Dapper J, Thiruvenkatam R, Lessman CA, Taylor MR, Gilbertson RJ. Eden CJ, et al. Oncogene. 2015 Mar 26;34(13):1736-42. doi: 10.1038/onc.2014.107. Epub 2014 Apr 21. Oncogene. 2015. PMID: 24747973 Free PMC article.
C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma.
Parker M, Mohankumar KM, Punchihewa C, Weinlich R, Dalton JD, Li Y, Lee R, Tatevossian RG, Phoenix TN, Thiruvenkatam R, White E, Tang B, Orisme W, Gupta K, Rusch M, Chen X, Li Y, Nagahawhatte P, Hedlund E, Finkelstein D, Wu G, Shurtleff S, Easton J, Boggs K, Yergeau D, Vadodaria B, Mulder HL, Becksfort J, Gupta P, Huether R, Ma J, Song G, Gajjar A, Merchant T, Boop F, Smith AA, Ding L, Lu C, Ochoa K, Zhao D, Fulton RS, Fulton LL, Mardis ER, Wilson RK, Downing JR, Green DR, Zhang J, Ellison DW, Gilbertson RJ. Parker M, et al. Nature. 2014 Feb 27;506(7489):451-5. doi: 10.1038/nature13109. Epub 2014 Feb 19. Nature. 2014. PMID: 24553141 Free PMC article.
Neoplastic causes of abnormal puberty.
Wendt S, Shelso J, Wright K, Furman W. Wendt S, et al. Pediatr Blood Cancer. 2014 Apr;61(4):664-71. doi: 10.1002/pbc.24825. Epub 2013 Oct 24. Pediatr Blood Cancer. 2014. PMID: 24155044 Free PMC article.
Metabolic activation of CaMKII by coenzyme A.
McCoy F, Darbandi R, Lee HC, Bharatham K, Moldoveanu T, Grace CR, Dodd K, Lin W, Chen SI, Tangallapally RP, Kurokawa M, Lee RE, Shelat AA, Chen T, Green DR, Harris RA, Lin SH, Fissore RA, Colbran RJ, Nutt LK. McCoy F, et al. Mol Cell. 2013 Nov 7;52(3):325-39. doi: 10.1016/j.molcel.2013.08.043. Epub 2013 Oct 3. Mol Cell. 2013. PMID: 24095281 Free PMC article.
Clinical significance of CD33 nonsynonymous single-nucleotide polymorphisms in pediatric patients with acute myeloid leukemia treated with gemtuzumab-ozogamicin-containing chemotherapy.
Mortland L, Alonzo TA, Walter RB, Gerbing RB, Mitra AK, Pollard JA, Loken MR, Hirsch B, Raimondi S, Franklin J, Pounds S, Cao X, Rubnitz JE, Ribeiro RC, Gamis A, Meshinchi S, Lamba JK. Mortland L, et al. Clin Cancer Res. 2013 Mar 15;19(6):1620-7. doi: 10.1158/1078-0432.CCR-12-3115. Epub 2013 Feb 26. Clin Cancer Res. 2013. PMID: 23444229 Free PMC article.
Novel mutations target distinct subgroups of medulloblastoma.
Robinson G, Parker M, Kranenburg TA, Lu C, Chen X, Ding L, Phoenix TN, Hedlund E, Wei L, Zhu X, Chalhoub N, Baker SJ, Huether R, Kriwacki R, Curley N, Thiruvenkatam R, Wang J, Wu G, Rusch M, Hong X, Becksfort J, Gupta P, Ma J, Easton J, Vadodaria B, Onar-Thomas A, Lin T, Li S, Pounds S, Paugh S, Zhao D, Kawauchi D, Roussel MF, Finkelstein D, Ellison DW, Lau CC, Bouffet E, Hassall T, Gururangan S, Cohn R, Fulton RS, Fulton LL, Dooling DJ, Ochoa K, Gajjar A, Mardis ER, Wilson RK, Downing JR, Zhang J, Gilbertson RJ. Robinson G, et al. Nature. 2012 Aug 2;488(7409):43-8. doi: 10.1038/nature11213. Nature. 2012. PMID: 22722829 Free PMC article.
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.
Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG. Zhang J, et al. Nature. 2012 Jan 11;481(7380):157-63. doi: 10.1038/nature10725. Nature. 2012. PMID: 22237106 Free PMC article.
An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma.
Atkinson JM, Shelat AA, Carcaboso AM, Kranenburg TA, Arnold LA, Boulos N, Wright K, Johnson RA, Poppleton H, Mohankumar KM, Féau C, Phoenix T, Gibson P, Zhu L, Tong Y, Eden C, Ellison DW, Priebe W, Koul D, Yung WK, Gajjar A, Stewart CF, Guy RK, Gilbertson RJ. Atkinson JM, et al. Cancer Cell. 2011 Sep 13;20(3):384-99. doi: 10.1016/j.ccr.2011.08.013. Cancer Cell. 2011. PMID: 21907928 Free PMC article.
Structural regulation of cullin-RING ubiquitin ligase complexes.
Duda DM, Scott DC, Calabrese MF, Zimmerman ES, Zheng N, Schulman BA. Duda DM, et al. Curr Opin Struct Biol. 2011 Apr;21(2):257-64. doi: 10.1016/j.sbi.2011.01.003. Epub 2011 Feb 1. Curr Opin Struct Biol. 2011. PMID: 21288713 Free PMC article. Review.
Subtypes of medulloblastoma have distinct developmental origins.
Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ. Gibson P, et al. Nature. 2010 Dec 23;468(7327):1095-9. doi: 10.1038/nature09587. Epub 2010 Dec 8. Nature. 2010. PMID: 21150899 Free PMC article.
Cross-species genomics matches driver mutations and cell compartments to model ependymoma.
Johnson RA, Wright KD, Poppleton H, Mohankumar KM, Finkelstein D, Pounds SB, Rand V, Leary SE, White E, Eden C, Hogg T, Northcott P, Mack S, Neale G, Wang YD, Coyle B, Atkinson J, DeWire M, Kranenburg TA, Gillespie Y, Allen JC, Merchant T, Boop FA, Sanford RA, Gajjar A, Ellison DW, Taylor MD, Grundy RG, Gilbertson RJ. Johnson RA, et al. Nature. 2010 Jul 29;466(7306):632-6. doi: 10.1038/nature09173. Epub 2010 Jul 18. Nature. 2010. PMID: 20639864 Free PMC article.