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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 3
1947 4
1948 3
1949 3
1950 3
1951 11
1952 9
1953 6
1954 12
1955 7
1956 5
1957 14
1958 14
1959 17
1960 19
1961 19
1962 23
1963 46
1964 61
1965 70
1966 180
1967 215
1968 214
1969 200
1970 209
1971 186
1972 199
1973 231
1974 297
1975 369
1976 408
1977 603
1978 982
1979 1194
1980 15685
1981 33527
1982 34552
1983 35009
1984 36722
1985 37425
1986 38598
1987 39963
1988 41078
1989 42720
1990 44831
1991 46118
1992 46704
1993 47438
1994 48932
1995 49323
1996 49509
1997 49843
1998 50842
1999 52366
2000 54953
2001 56299
2002 59392
2003 63609
2004 71270
2005 77918
2006 86536
2007 93109
2008 103272
2009 110092
2010 119490
2011 128555
2012 133228
2013 138273
2014 139661
2015 140801
2016 136186
2017 131623
2018 134165
2019 136088
2020 148706
2021 156069
2022 143647
2023 144993
2024 141048
2025 134620
2026 49696
2027 2

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3,533,259 results

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Page 1
State-level restorative justice policies and mental health disparities among girl dating violence survivors in the US: A lagged cross-sectional study.
Sharpless L, Austin A, Willie TC, Kershaw T, Moracco B, Reyes L. Sharpless L, et al. BMC Public Health. 2026 Jul 13. doi: 10.1186/s12889-026-28413-x. Online ahead of print. BMC Public Health. 2026. PMID: 42443828
Restorative justice (RJ), a policy-based, survivor-centered approach to harm repair and accountability, may be a structural intervention to promote mental health among ADV girl survivors. However, little is known about whether and how state-level RJ policies are associated …
Restorative justice (RJ), a policy-based, survivor-centered approach to harm repair and accountability, may be a structural intervention to …
Early life nicotine vapor exposure increases nicotine vapor seeking in adult male rats.
Maynez-Anchondo L, Rohrer O, Urbina M, Aguilar Armenta J, Gonzalez-Gutierrez T, O'Dell LE, Mendez IA. Maynez-Anchondo L, et al. Psychopharmacology (Berl). 2026 Jul 14. doi: 10.1007/s00213-026-07122-8. Online ahead of print. Psychopharmacology (Berl). 2026. PMID: 42443622
RATIONALE: The ongoing epidemic of nicotine vaping use in adolescents and young adults presents a significant health concern, yet the long-term effects of nicotine vaping remain largely unknown. OBJECTIVE: The present study aimed to investigate how nicotine vapor intake ea …
RATIONALE: The ongoing epidemic of nicotine vaping use in adolescents and young adults presents a significant health concern, yet the …
Shared genetic architecture and neurobiological pathways of problematic alcohol use and anxiety disorders.
Shi M, Gunawan T, Malone SG, Setzer M, Piserchia Z, Davis CN, Rentsch CT, Friligkou E, Zhou H, Polimanti R, Wang L, Vaitinadin NS, Kranzler HR, Gray JC. Shi M, et al. Neuropsychopharmacology. 2026 Jul 13. doi: 10.1038/s41386-026-02494-z. Online ahead of print. Neuropsychopharmacology. 2026. PMID: 42443535
We used FUMA to map single-nucleotide polymorphisms (SNPs) to independent loci, conduct differential gene expression analyses across 30 general and 54 specific tissue types, and perform cell-type specificity analyses using a human brain cell atlas. Druggability of identifi …
We used FUMA to map single-nucleotide polymorphisms (SNPs) to independent loci, conduct differential gene expression analyses across 30 gene …
Pervasive interactions between exposures and polygenic risk can inform more effective clinical and behavioral interventions.
Nagpal S, Gibson G. Nagpal S, et al. Nat Genet. 2026 Jul 13. doi: 10.1038/s41588-026-02674-z. Online ahead of print. Nat Genet. 2026. PMID: 42443528
Differences in disease prevalence across groups, potentially including social strata, influence the relationship between PGS and risk. Here we quantified the magnitude of PGS-by-context (PGS C) interactions for seven human diseases and pairs of 75 contexts in the UK …
Differences in disease prevalence across groups, potentially including social strata, influence the relationship between PGS and risk …
A universal 6iL/E4 culture system for deriving and maintaining embryonic stem cells across mammalian species.
Wang D, Ming H, Yang D, Cui X, Freeman Z, Tsai LK, Wei Z, Liu L, Scatolin GN, Bennett B, Wang X, Yau K, Tao L, Tong X, Wang S, Shi KX, Evseenko D, Van Handel B, Guo L, Dai X, Xiong Y, Zhang B, Wang Y, Iyyappan R, Ojeda-Rojas OA, Hu G, McGinnis L, Paulson R, Mckim D, Kong X, Xia X, Zhang J, Chen YE, Jiang Z, Xu J, Ying QL. Wang D, et al. Cell Res. 2026 Jul 13. doi: 10.1038/s41422-026-01276-y. Online ahead of print. Cell Res. 2026. PMID: 42443522
Importantly, we demonstrated that 6iL robustly establishes and maintains human pluripotent stem cells in a naive-like state. These findings reveal conserved principles underlying ESC self-renewal across divergent mammalian species and provide a universal platform for cross …
Importantly, we demonstrated that 6iL robustly establishes and maintains human pluripotent stem cells in a naive-like state. These fi …
The oral microbiome is associated with stress, adversity, and mental health in young adults.
Gancz NN, Savoca PW, Callaghan BL. Gancz NN, et al. Sci Rep. 2026 Jul 13. doi: 10.1038/s41598-026-60803-4. Online ahead of print. Sci Rep. 2026. PMID: 42443351
Acute stress responsivity and early-life adversity are both associated with oral microbiome differences that lead to increased mental and physical health risk. However, the joint association of stress responsivity and early adversity with the oral microbiome is not yet und …
Acute stress responsivity and early-life adversity are both associated with oral microbiome differences that lead to increased mental and ph …
Restriction spectrum imaging reveals brain microstructural correlates of obesity risk in early childhood.
Bayat M, Braun B, Curzon M, Hernandez ML, Curtis M, Coccia C, Garic D, Watts R, Irfanoglu MO, Graziano PA, Dick AS. Bayat M, et al. Sci Rep. 2026 Jul 13. doi: 10.1038/s41598-026-61029-0. Online ahead of print. Sci Rep. 2026. PMID: 42443271
Pediatric obesity is a growing public health concern, yet the early neurobiological correlates of obesity risk remain underexplored. ...
Pediatric obesity is a growing public health concern, yet the early neurobiological correlates of obesity risk remain underexplored. …
MR-based skull parametric modeling for blood-brain barrier opening in non-human primates.
Jiménez-Gambín S, Tsitsos F, Bae S, Ji R, Konofagou EE. Jiménez-Gambín S, et al. Sci Rep. 2026 Jul 13. doi: 10.1038/s41598-026-60478-x. Online ahead of print. Sci Rep. 2026. PMID: 42443259
Zero echo time (ZTE) magnetic resonance imaging (MRI) is a safe alternative for blood-brain barrier opening (BBBO) planning in non-human primates (NHP), with good contrast for bone imaging. In this study, we applied a classical coordinate-to-coordinate linear-regression me …
Zero echo time (ZTE) magnetic resonance imaging (MRI) is a safe alternative for blood-brain barrier opening (BBBO) planning in non-human
Oncogenic Ras drives EED degradation and PRC2 dysfunction to promote aggressive squamous cell carcinoma.
Li MY, Houser A, Cheema P, Zheng XY, Restrepo P, Flora P, Zhou Y, Segal-Dalal G, Silberstein E, Zhang X, Schober M, Zheng D, Cohen I, Ji AL, Ezhkova E. Li MY, et al. Nat Commun. 2026 Jul 13. doi: 10.1038/s41467-026-75529-0. Online ahead of print. Nat Commun. 2026. PMID: 42443217
Here, we uncover a paradox: although EZH2 is elevated, the PRC2-catalyzed H3K27me3 is profoundly reduced in human SCC and complementary murine models. Mechanistically, we identify that oncogenic Ras signaling causes degradation of the PRC2 subunit EED, destabilizing PRC2 a …
Here, we uncover a paradox: although EZH2 is elevated, the PRC2-catalyzed H3K27me3 is profoundly reduced in human SCC and complementa …
MARCKS as a mediator and target for pathological tunneling nanotubes between patient-derived glioblastoma cells and astrocytes.
Nassour-Caswell LC, Ahmed M, Rich-New ST, Schanel TL, Kumar M, Eustace NJ, Rohrbach TD, Jarboe JS, Hicks PH, Anderson JC, Willey CD. Nassour-Caswell LC, et al. Cell Death Dis. 2026 Jul 13. doi: 10.1038/s41419-026-09109-x. Online ahead of print. Cell Death Dis. 2026. PMID: 42443154
This dynamic is exemplified in GBM, where TNT-mediated interactions between brain tumor-initiating cells (BTICs) and normal human astrocytes (NHAs) highlight the need to elucidate the molecular mediators underlying this crosstalk. ...
This dynamic is exemplified in GBM, where TNT-mediated interactions between brain tumor-initiating cells (BTICs) and normal human ast …
Outcomes for persons with triple-class resistant HIV and a history of virologic failure.
Ingle SM, Bonnet F, Wittkop L, Calmy A, Teira R, Rebeiro PF, Crane HM, Stephan C, van der Valk M, Boesecke C, Touloumi G, Gill MJ, Grabmeier-Pfistershammer K, Garcia F, Ceccherini-Silberstein F, Burkholder G, Trickey A, Sterne JAC, Hessamfar M; Antiretroviral Therapy Cohort Collaboration (ART-CC). Ingle SM, et al. Int J Antimicrob Agents. 2026 Jul 13:107925. doi: 10.1016/j.ijantimicag.2026.107925. Online ahead of print. Int J Antimicrob Agents. 2026. PMID: 42442619
High-resolution reconstruction of cell-type-specific transcriptional regulatory processes from bulk sequencing samples.
Yao L, Shah SR, Ozer A, Zhu Y, Pan X, Xia T, Zhang J, Leung AK, Wei M, Lis JT, Yu H. Yao L, et al. Nat Biotechnol. 2026 Jul 13. doi: 10.1038/s41587-026-03218-w. Online ahead of print. Nat Biotechnol. 2026. PMID: 42443492
Using DeepDETAILS, we generated a compendium of high-resolution nascent transcription and histone modification signals across 39 diverse human tissues and 86 distinct cell types. Furthermore, we applied our compendium to fine-map risk variants associated with primary scler …
Using DeepDETAILS, we generated a compendium of high-resolution nascent transcription and histone modification signals across 39 diverse …
Genetic or pharmacological inhibition of hepatic TMEM141 attenuates MASH and fibrosis via the ROS-HNF4α signaling pathway.
Wang J, Chen CL, Gopoju R, Hu S, Wang Y, Wang H, Batayneh Z, Pan X, Chen YR, Mellott J, Kang P, Gunawardana L, Yin L, Zhang Y. Wang J, et al. Nat Commun. 2026 Jul 13. doi: 10.1038/s41467-026-75425-7. Online ahead of print. Nat Commun. 2026. PMID: 42443224
Unexpectedly, genetic inactivation of hepatocyte TMEM141 protects against MASLD/MASH induced by a high fat/cholesterol/fructose (HFCF) diet, whereas hepatic overexpression of human TMEM141 exacerbates MASLD/MASH. We further show that TMEM141 localizes within mitochondria a …
Unexpectedly, genetic inactivation of hepatocyte TMEM141 protects against MASLD/MASH induced by a high fat/cholesterol/fructose (HFCF) diet, …
Antibody reveals conformational latch regulating dimerization in β- and γ-herpesvirus proteases.
Zimanyi MA, Hulce KR, Bohn MF, Norman J, Rohweder PJ, Detomasi TC, Cheng Y, Craik CS. Zimanyi MA, et al. Nat Commun. 2026 Jul 13. doi: 10.1038/s41467-026-75438-2. Online ahead of print. Nat Commun. 2026. PMID: 42443199
Human herpesvirus (HHV) replication depends on the HHV protease (HHV Pr), an enzyme essential for capsid maturation. ...We isolate Fab5, a conformationally selective antibody from a naive Fab-phage library that recognizes monomeric human cytomegalovirus protease (HC
Human herpesvirus (HHV) replication depends on the HHV protease (HHV Pr), an enzyme essential for capsid maturation. ...We isolate Fa
ERG preserves endothelial identity to limit atherosclerosis.
Botts SR, Scipione CA, Schulz K, Breda LCD, Ellis K, Ho C, Raju S, Prajapati K, Yu K, Khan AB, Polenz CK, Prattas SZ, Hyduk SJ, Cao C, Wythe JD, Robbins CS, Miller CL, Cybulsky MI, Fish JE, Howe KL. Botts SR, et al. Nat Commun. 2026 Jul 13. doi: 10.1038/s41467-026-75287-z. Online ahead of print. Nat Commun. 2026. PMID: 42443196
ERG loss also caused early disruption of barrier function, promoting lipid uptake and foam cell accumulation in normally atheroresistant regions. In human atherosclerotic plaques, ERG chromatin accessibility and expression were reduced, with transcriptional changes mirrori …
ERG loss also caused early disruption of barrier function, promoting lipid uptake and foam cell accumulation in normally atheroresistant reg …
Placenta models for HIV-1-ART-nicotine comorbidity research: advances and remaining challenges.
Godse S, Bade AN. Godse S, et al. Cell Death Discov. 2026 Jul 13. doi: 10.1038/s41420-026-03249-x. Online ahead of print. Cell Death Discov. 2026. PMID: 42443152 Review.
Worldwide implementation of antiretroviral therapy (ART) for pregnant women living with human immunodeficiency virus type-1 (HIV-1) has markedly reduced mother-to-child HIV-1 transmission rate to less than one percent. ...
Worldwide implementation of antiretroviral therapy (ART) for pregnant women living with human immunodeficiency virus type-1 (HIV-1) h …
Discrepancies between self-reported alcohol use and breathalyzer results and factors associated with blood alcohol concentration positivity among road traffic injury patients in Cameroon.
Ngekeng S, Oke R, Kibu O, Tanue E, Tendongfor N, Nguefack-Tsague G, Hubbard A, Shoptaw S, Chichom-Mefire A, Juillard C. Ngekeng S, et al. Addiction. 2026 Jul 13. doi: 10.1111/add.70537. Online ahead of print. Addiction. 2026. PMID: 42443067
Participants underwent structured interviews and breathalyzer testing upon presentation to the emergency department within six hours of injury. SETTING: Limbe Regional Hospital and Edea Regional Hospital Annex in Cameroon, both of which are part of the Cameroon Trauma Regi …
Participants underwent structured interviews and breathalyzer testing upon presentation to the emergency department within six hours …
Abbreviated DAPT Regimens Across the Entire Spectrum of Bleeding Risk According to the PRECISE-HBR Score.
Cao D, Oliva A, Mehran R, Sartori S, Feng Y, Gragnano F, van Klaveren D, Angiolillo DJ, Bangalore S, Bhatt DL, Ge J, Hermiller J, Makkar RR, Neumann FJ, Saito S, Picon H, Toelg R, Maksoud A, Chehab BM, Choi JW, Campo G, de la Torre Hernandez JM, Krucoff MW, Kunadian V, Sardella G, Thiele H, Varenne O, Vranckx P, Windecker S, Valgimigli M. Cao D, et al. JACC Cardiovasc Interv. 2026 Jul 13;19(13):1766-1777. doi: 10.1016/j.jcin.2026.04.051. JACC Cardiovasc Interv. 2026. PMID: 42442892
Procedural Strategies for Optimal Transcatheter Aortic Valve Replacement: An International Position Statement.
Maznyczka A, Pilgrim T, Hildick-Smith D, Mangieri A, Latib A, Abdel-Wahab M, Alkhouli M, Webb JG, Reardon MJ, Herrmann HC, Blackman DJ, Nombela-Franco L, Rudolph TK, Wykrzykowska JJ, Barbanti M, Joner M, Généreux P, Russell K, Saint-Etienne C, Akodad M, Kobari Y, Meier D, Van Mieghem N, Rogers T, Kodali S, Ohno Y, Angellotti D, Prendergast B, Dvir D, Mylotte D, Tchétché D, Piazza N, De Backer O. Maznyczka A, et al. JACC Cardiovasc Interv. 2026 Jul 13;19(13):1713-1734. doi: 10.1016/j.jcin.2026.04.049. JACC Cardiovasc Interv. 2026. PMID: 42442887 Review.
Risk Factors Associated with Delivery Hospitalization Pulmonary Embolism.
Wang R, Agarwal J, Huang Y, Wen T, D'Alton M, Friedman AM. Wang R, et al. Am J Perinatol. 2026 Jul 13. doi: 10.1055/a-2911-5301. Online ahead of print. Am J Perinatol. 2026. PMID: 42442713
OBJECTIVE: The objectives of this study were to analyze trends in obstetric PE and to determine how clinical risk factors have contributed to changes in pulmonary embolism risk over the study period. STUDY DESIGN: The 2000-2021 National Inpatient Sample was used for this c …
OBJECTIVE: The objectives of this study were to analyze trends in obstetric PE and to determine how clinical risk factors have contributed t …
Emergence of Reassortant Crimean-Congo Hemorrhagic fever virus lineages, Pakistan, 2023-2024.
Umair M, Jamal Z, Ali Q, Hakim R, Rana MS, Javed Y, Bugti AR, Ayub A, Sabeen F, Waheed Y, Salman M. Umair M, et al. Infect Genet Evol. 2026 Jul 13:105988. doi: 10.1016/j.meegid.2026.105988. Online ahead of print. Infect Genet Evol. 2026. PMID: 42442443
Crimean-Congo hemorrhagic fever virus (CCHFV) remains endemic in Pakistan, yet whole-genome data are limited. During 2023-2024 national surveillance, 151 suspected cases were screened by qRT-PCR; 23 were confirmed at the NIH, Islamabad. ...These findings underscore …
Crimean-Congo hemorrhagic fever virus (CCHFV) remains endemic in Pakistan, yet whole-genome data are limited. During 2023-2024 national
HIV acquisitions, safety, and pharmacokinetics of lenacapavir for HIV pre-exposure prophylaxis in pregnant and lactating women (PURPOSE 1): a substudy of a phase 3, randomised controlled trial.
Bekker LG, Moodley D, Diallo DD, Harkoo I, Kigozi G, Kiwanuka N, Louw CE, Malahleha M, Mworeko L, Palanee-Phillips T, Panchia R, Singh N, Puryear SB, Arora P, Baeten JM, Brown A, Carter CC, Imperial M, Ling J, Singh R, Wong P, Das M, Kiweewa FM. Bekker LG, et al. Lancet HIV. 2026 Jul 13:S2352-3018(26)00112-8. doi: 10.1016/S2352-3018(26)00112-8. Online ahead of print. Lancet HIV. 2026. PMID: 42442378
The role of sweat chloride in determining CFTR protein restoration in people with cystic fibrosis.
Zemanick ET, Graeber SY, Castellani C, Cutting GR, Fajac I, Konstan MW, Linnemann RW, McKone EF, Metcalf A, Solomon GM, Taylor-Cousar JL, Mayer-Hamblett N, Mall MA. Zemanick ET, et al. Lancet Respir Med. 2026 Jul 13:S2213-2600(26)00159-1. doi: 10.1016/S2213-2600(26)00159-1. Online ahead of print. Lancet Respir Med. 2026. PMID: 42442377 Review.
For many people with cystic fibrosis with responsive variants and drug access, treatment with CFTR modulators increases CFTR function, reduces sweat chloride concentrations, and improves lung health and quality of life. In clinical trials, average sweat chloride reduction …
For many people with cystic fibrosis with responsive variants and drug access, treatment with CFTR modulators increases CFTR function, reduc …
Reproductive health guidance for the cystic fibrosis community: a Cystic Fibrosis Foundation Position Paper.
Jain R, Taylor JL, Kazmerski TM, Lonabaugh K, Trimble A, Velez Leitner D, Foil K, Hong G, Johns WB, Kolarova T, Meier E, Perry A, Singh KE, Stahl C, Szentpetery S, Weiss MS, West NE, Wilson A, Wright B, Brown AW, Hempstead SE, Lomas P, Middleton PG, Shteinberg M, Felton I, Roe AH. Jain R, et al. Lancet Respir Med. 2026 Jul 13:S2213-2600(26)00120-7. doi: 10.1016/S2213-2600(26)00120-7. Online ahead of print. Lancet Respir Med. 2026. PMID: 42442376 Review.
The Cystic Fibrosis Foundation organised a multidisciplinary committee to develop this Position Paper to outline current knowledge and best practices in reproductive health care for individuals with cystic fibrosis. Working groups reviewed the literature and provided relev …
The Cystic Fibrosis Foundation organised a multidisciplinary committee to develop this Position Paper to outline current knowledge and best …
Dementia prevention in Latin America and the Global South.
Fortea J, Ikanga J, de Paula França Resende E. Fortea J, et al. Lancet. 2026 Jul 13:S0140-6736(26)01373-5. doi: 10.1016/S0140-6736(26)01373-5. Online ahead of print. Lancet. 2026. PMID: 42442375 No abstract available.
Multidomain lifestyle intervention for the prevention of cognitive decline in at-risk older adults in Latin America (LatAm-FINGERS): a single-blind, multicentre, randomised controlled trial.
Crivelli L, Suemoto CK, Sosa AL, Lopera F, Aguillón D, Allegri RF, Nitrini R, Calandri IL, Velilla-Jiménez L, Yassuda MS, Acosta-Baena N, Salinas RM, Charamelo A, Derio CD, Acosta DM, León-Salas JM, Duque-Peñailillo L, Cusicanqui MI, Custodio N, Anchia-Alfaro A, Núñez-Herrera A, Rubens A, Leites A, Vigil-Martínez A, Damian A, Flores-Blanco BM, Custodio B, Laforcada C, Márquez C, Friedlaender CV, Espinoza-Cruz CG, Cañadas C, Peixoto C, Muñoz DH, Slezak DF, Felix E, Aguirre-Salvador E, Surace EI, Mariani F, De La Torre GR, Verástegui G, Keller G, Peixoto GH, Morilla HA, Jiménez-Velázquez IZ, More JY, Rodríguez JF, Tosatti JAG, de Faria Rocha JV, Saldarriaga-Hernández J, Huilca JC, García-Molina JT, Martínez-Galindo JG, Duran JC, Rodriguez JG, Gomes KB, César-Freitas KG, Agüero K, Mora-Villalobos L, Asprilla LO, de Souza LC, Soto L, Cortabarría L, Baldeón L, Carreira LL, Marin-Buitrago L, Moreno MC, Barbosa MT, Torheim M, Magalhães MAZ, da Graça Morais Martin M, Martin ME, Torres MF, Menéndez M, Hernandez MA, Granizo MS, Gutiérrez M, Corvalán N, Mora PJ, Peguero P, Ramírez-Santos R, Fernández RS, Montesinos R, Ospina-Henao S, Montes SY, Santero S, Brucki SMD, Josephy-Hernandez S, Vaz… See abstract for full author list ➔ Crivelli L, et al. Lancet. 2026 Jul 13:S0140-6736(26)01278-X. doi: 10.1016/S0140-6736(26)01278-X. Online ahead of print. Lancet. 2026. PMID: 42442374
The SLI provided structured multidomain lifestyle interventions with supervised support and monitoring; FLI offered health advice. Primary outcomes were trial feasibility (evaluated using selected RE-AIM measures: Reach, Implementation, and Maintenance) and the interventio …
The SLI provided structured multidomain lifestyle interventions with supervised support and monitoring; FLI offered health advice. Pr …
Perfluorooctanoic acid and cancer incidence: an updated investigation of a cohort in the mid-Ohio Valley.
Hofmann JN, Tan Y, Barry V, Taylor A, Winquist A, Hyer M, Graubard BI, Steenland K, Silverman DT. Hofmann JN, et al. Environ Int. 2026 Jul 10;214:110405. doi: 10.1016/j.envint.2026.110405. Online ahead of print. Environ Int. 2026. PMID: 42442238
BACKGROUND: Perfluorooctanoic acid (PFOA) has been classified as a human carcinogen based partly on limited epidemiologic evidence of increased kidney and testicular cancer risk. ...
BACKGROUND: Perfluorooctanoic acid (PFOA) has been classified as a human carcinogen based partly on limited epidemiologic evidence of …
Multiomic characterization of DNA released after airway exposure to allergens and nanoparticles reveals selective export of repetitive and fragile site DNA.
Law K, Srisomboon Y, Iijima K, Faulk C, Kita H, O'Grady SM. Law K, et al. Physiol Genomics. 2026 Jul 13. doi: 10.1152/physiolgenomics.00029.2026. Online ahead of print. Physiol Genomics. 2026. PMID: 42441982
Nanopore sequencing along with a multi-omics approach were employed to analyze fragments of extracellular DNA (eDNA) in human and mouse airway epithelial cells and bronchoalveolar lavage fluid from mice. We show that eDNA release following Alternaria or PEI exposure produc …
Nanopore sequencing along with a multi-omics approach were employed to analyze fragments of extracellular DNA (eDNA) in human and mou …
Glucagon-Like Peptide-1 Receptor Agonists and Risk for Ischemic Optic Neuropathy : A Target Trial Emulation.
Reynolds KR, O'Malley KM, Roy JA, Dave CV. Reynolds KR, et al. Ann Intern Med. 2026 Jul 14. doi: 10.7326/ANNALS-25-00860. Online ahead of print. Ann Intern Med. 2026. PMID: 42441967
DESIGN: Observational emulation of a target trial. SETTING: Large U.S.-based commercial claims database (January 2017 to December 2022). PARTICIPANTS: Patients aged 18 to 65 years with type 2 diabetes initiating a GLP-1RA, an SGLT2i, or a DPP4i. ...Observed differen …
DESIGN: Observational emulation of a target trial. SETTING: Large U.S.-based commercial claims database (January 2017 to Decem …
Developmental divergence in voice-reward circuitry differentiates autistic from typically developing children and adolescents.
Abrams DA, Leipold S, Odriozola P, Baker AE, Padmanabhan A, Phillips JM, Menon V. Abrams DA, et al. Proc Natl Acad Sci U S A. 2026 Jul 21;123(29):e2601227123. doi: 10.1073/pnas.2601227123. Epub 2026 Jul 13. Proc Natl Acad Sci U S A. 2026. PMID: 42441858
Human voice processing is a primary driver of social learning and communication, but it remains understudied in the autism literature, particularly as it relates to neurodevelopmental change. ...More broadly, results suggest that individual differences in social
Human voice processing is a primary driver of social learning and communication, but it remains understudied in the autism lit
Enteroendocrine cells wire the gut-brain vagal axis.
Runyon A, Zhang P, Fischer AJ, Nonet ML, Lillesaar C, Ye L. Runyon A, et al. Proc Natl Acad Sci U S A. 2026 Jul 21;123(29):e2600339123. doi: 10.1073/pnas.2600339123. Epub 2026 Jul 13. Proc Natl Acad Sci U S A. 2026. PMID: 42441856
Role of Pbr1, a putative oxidoreductase, in the ER quality control and folding of yeast Fks1 glucan synthase.
Obara K, Okada H, Tan G, Ohnuki S, Suzuki G, Ohtake H, Kubo K, Ghanegolmohammadi F, Ishizaka S, Yashiroda Y, Okita A, Mishiro-Sato E, Suzuki K, Tamura Y, Ashine R, Ikeda Y, Kamura T, van Leeuwen J, Andrews B, Bi E, Noda NN, Boone C, Ohya Y. Obara K, et al. Proc Natl Acad Sci U S A. 2026 Jul 21;123(29):e2612792123. doi: 10.1073/pnas.2612792123. Epub 2026 Jul 13. Proc Natl Acad Sci U S A. 2026. PMID: 42441850
Paintable on-skin dry electrodes with robust skin and device connection for wireless sensing and human-machine interfaces.
Zhang W, Xin X, Wang Y, Zhang X, Zhang S, Yuan Y, Xia S, Abdullah AM, Zohra FT, Li B, Yang JY, Dutta A, Liu Z, Lima ABP, Yan S, Zhong J, Chuang CH, Cheng H. Zhang W, et al. Proc Natl Acad Sci U S A. 2026 Jul 21;123(29):e2615835123. doi: 10.1073/pnas.2615835123. Epub 2026 Jul 13. Proc Natl Acad Sci U S A. 2026. PMID: 42441849
Reliable and continuous electrophysiological recording is important for health monitoring and human-machine interactions. However, most existing epidermal electrodes suffer from either limited skin-electrode contact during skin deformation and sweating, or unstable …
Reliable and continuous electrophysiological recording is important for health monitoring and human-machine interactions. Howe …
Pseudokinase-converting mutation in protein kinase C alpha drives chordoid glioma by pathway rewiring.
Bellamy C, Tovell H, Kao TH, Kornev A, Letourneur Q, Arslan J, Schwaighofer S, Baffi TR, Dingli F, Loew D, Lerond J, Liva S, Izac B, Andrieu M, Adle-Biassette H, Barnier JV, Stefan E, Taylor SS, Sanson M, Newton AC, Bielle F. Bellamy C, et al. Proc Natl Acad Sci U S A. 2026 Jul 21;123(29):e2524934123. doi: 10.1073/pnas.2524934123. Epub 2026 Jul 13. Proc Natl Acad Sci U S A. 2026. PMID: 42441840
Assessing the abuse liability of U.S. Food and Drug Administration-authorized electronic nicotine delivery systems: Impact of nicotine flux, flavor, and menthol cigarette smoking status.
Ogunleye EO, Bono RS, Imran R, Gaitan N, Lipato T, Barnes AJ, Cobb CO. Ogunleye EO, et al. Exp Clin Psychopharmacol. 2026 Jul 13. doi: 10.1037/pha0000861. Online ahead of print. Exp Clin Psychopharmacol. 2026. PMID: 42441607
The U.S. Food and Drug Administration has authorized 41 electronic nicotine delivery systems (ENDS) that meet its public health standard. ...Findings support further investigation on menthol-flavored, higher flux ENDS for public health benefit. (PsycIn …
The U.S. Food and Drug Administration has authorized 41 electronic nicotine delivery systems (ENDS) that meet its public he
Clinical Profile of Neurofibromatosis Type 1: Paediatric Patients from a Tertiary Care Centre.
Mendiratta V, Verma B, Bindal A. Mendiratta V, et al. Indian J Dermatol. 2026 Jul-Aug;71(4):306-309. doi: 10.4103/ijd.ijd_389_25. Epub 2026 Jun 30. Indian J Dermatol. 2026. PMID: 42441148 Free PMC article.
The study was conducted at the paediatric dermatology outpatient department of a tertiary care hospital in Delhi. Records from a dedicated genodermatosis clinic were reviewed. Children fulfilling the NIH diagnostic criteria for NF1 were included. Clinical features, …
The study was conducted at the paediatric dermatology outpatient department of a tertiary care hospital in Delhi. Records from a dedi …
The effect of probiotic supplements on cognitive outcomes and neuroplasticity in elderly ischemic stroke survivors.
Zheng X, Chen W, Hong K, Chen J, Lin Y, Yang J. Zheng X, et al. Front Neurol. 2026 Jun 22;17:1833163. doi: 10.3389/fneur.2026.1833163. eCollection 2026. Front Neurol. 2026. PMID: 42440737 Free PMC article.
METHODS: The study included 223 elderly ischemic stroke survivors treated between March 2021 and February 2024, divided into two groups based on treatment modalities: the Conventional Group (n = 117) receiving standard enteral nutrition, and the Supplement Group (n = 106) receivi …
METHODS: The study included 223 elderly ischemic stroke survivors treated between March 2021 and February 2024, divided into two groups base …
High resolution cryo-EM structure of the Pseudomonas aeruginosa OprM multidrug efflux pump provides target for rational inhibitor design.
Ratliff AC, Botos I, Putti AM, Patil PP, Ramkumar A, Ghirlando R, Dekker JP, Buchanan SK. Ratliff AC, et al. J Struct Biol X. 2026 Jun 27;14:100152. doi: 10.1016/j.yjsbx.2026.100152. eCollection 2026 Dec. J Struct Biol X. 2026. PMID: 42440500 Free PMC article.
OprM is the outer membrane channel component of resistance-nodulation-division (RND) efflux pumps in Pseudomonas aeruginosa, a high-priority human pathogen. OprM-dependent pumps play diverse roles in bacterial physiology and mediate resistance to critical antibiotic classe …
OprM is the outer membrane channel component of resistance-nodulation-division (RND) efflux pumps in Pseudomonas aeruginosa, a high-priority …
Synthetic developmental engineering of human liver organogenesis.
Taheri MN, Xiang Y, Ebrahimkhani MR. Taheri MN, et al. Development. 2026 Jul 1;153(13):dev205040. doi: 10.1242/dev.205040. Epub 2026 Jul 13. Development. 2026. PMID: 42440359 Review.
In this Review, we discuss liver development in the human embryo and current models that are routinely used for generating liver organoids in vitro as well as their limitations. ...Together, these approaches pave the way for next-generation multicellular human stem …
In this Review, we discuss liver development in the human embryo and current models that are routinely used for generating liver orga …
PDA (Privacy-Preserving Distributed Algorithms) in action: ten principles for high-quality multi-site clinical evidence generation.
Chen Y, Tong J, Lu Y, Duan R, Luo C, Suchard MA, Ryan PB, Williams AE, Holmes JH, Moore JH, Xu H, Lu Y, Carroll RJ, Zeger SL, Hripcsak G, Schuemie MJ. Chen Y, et al. J Am Med Inform Assoc. 2026 Jul 13:ocag119. doi: 10.1093/jamia/ocag119. Online ahead of print. J Am Med Inform Assoc. 2026. PMID: 42440280
Over the last 10 years, Privacy-Preserving Distributed Algorithms (PDA) have been developed and utilized in numerous national and international real-world studies spanning diverse domains, from comparative effectiveness research, target trial emulation, to healthcare deliv …
Over the last 10 years, Privacy-Preserving Distributed Algorithms (PDA) have been developed and utilized in numerous national and int …
Occupational Risk of Low-Level Blast Exposure and Health Outcomes: A Longitudinal Study of Postdeployment Army Enlisted Active Duty Soldiers.
Adams RS, Huntington N, Carpenter J, Linton A, Moresco N, Dams-O'Connor K, Kumar RG, Highland KB, Larson MJ. Adams RS, et al. J Head Trauma Rehabil. 2026 Jun 26. doi: 10.1097/HTR.0000000000001191. Online ahead of print. J Head Trauma Rehabil. 2026. PMID: 42440265
OBJECTIVE: Evaluate the relationship between risk of occupational low-level blast (LLB) exposure and health outcomes (ie, substance use disorder, long-term opioid receipt, headaches, and back pain). ...CONCLUSION: Study results add to the existing research underscoring the …
OBJECTIVE: Evaluate the relationship between risk of occupational low-level blast (LLB) exposure and health outcomes (ie, substance u …
Plasticizing Diabetes Care: The Metabolic Threat of Plastic-Associated Endocrine Disruptors and Micro-/Nanoplastics in Clinical Medicine.
Sargis RM, Reutrakul S, Trasande L, Nadal A. Sargis RM, et al. Curr Diab Rep. 2026 Jul 13;26(1):21. doi: 10.1007/s11892-026-01635-4. Curr Diab Rep. 2026. PMID: 42440155 Review.
Plastic-associated EDCs and MNPs remain an underappreciated metabolic health threat. Mitigating the deleterious impacts of plastics on human and planetary health requires concerted actions from manufacturers, scientists, policymakers, professional organizatio …
Plastic-associated EDCs and MNPs remain an underappreciated metabolic health threat. Mitigating the deleterious impacts of plastics o …
Estimating Utility Values Using the DMD-QoL: A Disease-Specific Preference-Based Measure for Duchenne Muscular Dystrophy (DMD).
Bever A, Szabo SM, Jayasinghe P, Feeny D, Neumann PJ, Malone DC, Iannaccone ST, Gooch KL, Audhya IF. Bever A, et al. Adv Ther. 2026 Jul 13. doi: 10.1007/s12325-026-03700-6. Online ahead of print. Adv Ther. 2026. PMID: 42440040
Participants were classified into health states based on upper and lower limb function. Mean utility and change over 12 months were calculated by baseline health state and respondent type; change in utility was also estimated among those in whom declining ambulatory …
Participants were classified into health states based on upper and lower limb function. Mean utility and change over 12 months were c …
Uncontrolled Hypertension Prevalence, Characteristic Profiles, and Risk of Cardiorenal and Metabolic Outcomes: Insights from the EnligHTN Study.
McCormack T, Ben Dor NR, Norris T, Giannoula A, Coto E, Rhodes KM, Franzén S, Suárez Fernández C, Weil J, Bech JN, Bhalla V. McCormack T, et al. Adv Ther. 2026 Jul 13. doi: 10.1007/s12325-026-03681-6. Online ahead of print. Adv Ther. 2026. PMID: 42440039
Adults with a hypertension diagnosis after 2018 and a BP measurement after receiving 2 antihypertensives for 30 days (index date) were included. uHTN was defined based on index BP according to national guidelines (US: 130/80 mmHg; other countries: 140/90 mmHg). Dat …
Adults with a hypertension diagnosis after 2018 and a BP measurement after receiving 2 antihypertensives for 30 days (index date) were i …
Applications of Stem Cell-Derived Islets and Emerging Experimental Platforms to Understand Diabetes.
Mukherjee N, Millman JR. Mukherjee N, et al. Diabetes. 2026 Jul 13:db260013. doi: 10.2337/db26-0013. Online ahead of print. Diabetes. 2026. PMID: 42439827 Review.
We also discuss exciting emerging approaches that expand investigations beyond pancreatic endocrine cells to encompass nonendocrine cell types in the pancreas, offering a unique bird's-eye view into pancreatic biology and insights into cellular cross talk in health and dis …
We also discuss exciting emerging approaches that expand investigations beyond pancreatic endocrine cells to encompass nonendocrine cell typ …
1,25-Dihydroxyvitamin D Induces a NURR1-Tyrosine Hydroxylase Transcriptional Axis Modulated by Rexinoid/RXR Signaling in Parkinson's Disease-Relevant Human Neural Cell Models.
Sausedo MA, Mallick S, Sabir ZL, Livingston S, Nguyen QT, Doost ME, Wagner CE, Marshall PA, Haussler CA, Haussler MR, Jurutka PW. Sausedo MA, et al. Cells. 2026 Jul 3;15(13):1210. doi: 10.3390/cells15131210. Cells. 2026. PMID: 42439684
Herein we report that TH mRNA is significantly induced (2.5-fold) and NURR1 mRNA is induced 9.3-fold by 10 nM 1,25D in differentiated human SH-SY5Y neuroblastoma cells. Similar results were observed in human U87 glioblastoma cells (TH, 2.6-fold; NURR1, 3.6-fold). Co …
Herein we report that TH mRNA is significantly induced (2.5-fold) and NURR1 mRNA is induced 9.3-fold by 10 nM 1,25D in differentiated hum
MAFA: A Master Regulator of β-Cell Maturation and Function.
Johnson L, Maurer MA, Cha J. Johnson L, et al. Cells. 2026 Jul 1;15(13):1199. doi: 10.3390/cells15131199. Cells. 2026. PMID: 42439674 Review.
In this review, we summarize the current understanding of MAFA on beta-cell maturation and function in both the mouse and human. This includes structural features of the MAFA protein, regulation of MAFA transcription, post-translational modifications, and emerging areas of …
In this review, we summarize the current understanding of MAFA on beta-cell maturation and function in both the mouse and human. This …
Generation of Blood Vascular Endothelial-Neural 3D Organoids by Serial Induction of Differentiation on Human iPSC-Derived Embryoid Bodies.
Wang T, Bagnell A, McDonald V, Gastfriend BD, Steiner JP, Elkahloun AG, Johnson K, Langston RG, Cookson MR, Nath A. Wang T, et al. Cells. 2026 Jun 30;15(13):1192. doi: 10.3390/cells15131192. Cells. 2026. PMID: 42439668
However, these approaches could miss the developmental interactions between angiogenesis and neurogenesis in the human brain. To reconstitute a 3D organoid mimicking the in vivo development of neural and vascular endothelial cells, we cultured iPSC-derived embryoid bodies …
However, these approaches could miss the developmental interactions between angiogenesis and neurogenesis in the human brain. To reco …
Cyclic Mechanical Loading of Cardiomyocytes via Pressure-Driven Non-Planar Membrane Deformation in a Bioreactor System.
Mansoor H, Juul G, Patel J, Pradhan H, Hepner G, Jewell J, Bardin M, Slusser R, Glezer A, Klouda L, Tanyeri M, Saraf A. Mansoor H, et al. Adv Sci (Weinh). 2026 Jul 13:e23820. doi: 10.1002/advs.202523820. Online ahead of print. Adv Sci (Weinh). 2026. PMID: 42439440
Applied pressure was quantitatively related to spatial membrane strain through three-dimensional membrane reconstruction, enabling characterization of the mechanical environment at the cell-substrate interface. Human induced pluripotent stem cell-derived cardiomyocytes (hi …
Applied pressure was quantitatively related to spatial membrane strain through three-dimensional membrane reconstruction, enabling character …
Optimizing Antihypertensive Care for Tanzanians Living With HIV: Effectiveness Outcomes From the COACH Pilot Trial.
Hertz JT, Rahim F, Wang C, Vaidyanathan A, Wanda L, Sakita FM, Mmbaga BT, Kweka GL, Mlangi JJ, Zebedayo R, Gwasma F, Prakash T, Jafar TH, Bosworth HB, Thielman NM, Manavalan P. Hertz JT, et al. J Acquir Immune Defic Syndr. 2026 Aug 1;101(8):896-906. doi: 10.1097/QAI.0000000000003874. J Acquir Immune Defic Syndr. 2026. PMID: 42439100
BACKGROUND: In Tanzania, many people living with HIV have uncontrolled hypertension, yet integration of hypertension management into HIV care remains limited. The Community Health Worker Optimization of Antihypertensive Care in HIV (COACH) intervention was developed to int …
BACKGROUND: In Tanzania, many people living with HIV have uncontrolled hypertension, yet integration of hypertension management into HIV car …
The social environment and cognitive aging over the life course: laying out critical concepts and research gaps.
Hicken MT, DeAngelis R, Rigby D, Burnside L, Adar S, Burgard S, Davis BA, Donnelly R, Finlay JM, Hajat A, Lee J, Perry BL, Thorpe LE, Umberson D. Hicken MT, et al. Alzheimers Dement. 2026 Jul;22(7):e71648. doi: 10.1002/alz.71648. Alzheimers Dement. 2026. PMID: 42439047 Review.
The social environment refers to our interpersonal relations, workplaces, and neighborhoods, towns, or cities in which we live. ...Addressing this limitation, our paper outlines key features of the social environment and recommends priority areas of research on the …
The social environment refers to our interpersonal relations, workplaces, and neighborhoods, towns, or cities in which we live. ...Ad …
ChatGPT improves readability in validated spine patient-reported outcome measures.
Abdelmalek G, Shaikh S, Coban D, Elkholy A, Emami C, Sahai N, Hwang K, Sinha K. Abdelmalek G, et al. N Am Spine Soc J. 2026 Jun 8;27:100917. doi: 10.1016/j.xnsj.2026.100917. eCollection 2026 Sep. N Am Spine Soc J. 2026. PMID: 42438793 Free PMC article.
BACKGROUND: Spine patient-reported outcome measures (PROMs) frequently exceed recommended health literacy thresholds, limiting accessibility. Large language models (LLMs) such as ChatGPT can simplify medical text, but their effects on validated outcome instruments remain u …
BACKGROUND: Spine patient-reported outcome measures (PROMs) frequently exceed recommended health literacy thresholds, limiting access …
Application of machine learning algorithms in building health diagnostics: predictive analytics evaluating indoor air quality and sick building syndrome in educational settings.
Ismail SA, Kamar HM, Kamsah N, Lim KH, Kamaruzaman NA, Ramdan MI, Crüts B, Zaini Makhtar MM, Rafatullah M, Vashisht A. Ismail SA, et al. PeerJ. 2026 Jul 9;14:e20964. doi: 10.7717/peerj.20964. eCollection 2026. PeerJ. 2026. PMID: 42438712 Free PMC article.
The current assessment involved the use of the modified MM040NA SBS questionnaire and checklist from Indoor Air Quality (IAQ) Industry Code of Practice (IAQ-ICOP) from Department Occupational Safety and Health (DOSH), Malaysia, with participants scoring of their ans …
The current assessment involved the use of the modified MM040NA SBS questionnaire and checklist from Indoor Air Quality (IAQ) Industry Code …
Digital and computational innovations for posttraumatic stress disorder: How digital technologies can improve diagnosis, risk stratification, and individualized treatment.
Hilberdink CE, Huibregtse ME, Hinojosa CA, Dean GS, van Zuiden M, Schultebraucks K. Hilberdink CE, et al. J Trauma Stress. 2026 Jul 12. doi: 10.1002/jts.70108. Online ahead of print. J Trauma Stress. 2026. PMID: 42438276 Review.
Traditional assessments, which depend on retrospective recall and intermittent clinical contact, are limited in their ability to reflect the dynamic and context-sensitive processes that shape trauma-related mental health outcomes. Emerging digital health technologie …
Traditional assessments, which depend on retrospective recall and intermittent clinical contact, are limited in their ability to reflect the …
Nutrition and Exercise in Critical Illness (NEXIS) trial: randomized trial of combined in-bed cycling and intravenous amino acid plus usual care.
Needham DM, Files DC, Hough CL, Mayer KP, Ardren S, Fatima A, Jiang X, Day AG, Dinglas VD, Hiser SL, Kiyatkin ME, Khan A, Morris PE, Carson SS, Antkowiak M, Bakhru RN, Burns S, Nath SD, Gibbs KW, Gundel SJ, Kalema AG, Sturgill JL, Ventrone S, Heyland DK, Stapleton RD; With The NEXIS Study Team. Needham DM, et al. Am J Respir Crit Care Med. 2026 Jul 13:aamag287. doi: 10.1093/ajrccm/aamag287. Online ahead of print. Am J Respir Crit Care Med. 2026. PMID: 42438140
MEASUREMENTS AND MAIN RESULTS: In total, 115 patients (median age 55 years, 55% male, Acute Physiology and Chronic Health Evaluation II 24, >90% mechanically ventilated) were randomized (60 intervention; 55 control). ...
MEASUREMENTS AND MAIN RESULTS: In total, 115 patients (median age 55 years, 55% male, Acute Physiology and Chronic Health Evaluation …
The Effects of Incretin Mimetic Therapies on Muscle and Bone Health in Older Adults: A Narrative Review.
Saavedra JM, Chen AS, Porter Starr KN, Batsis JA. Saavedra JM, et al. Obesity (Silver Spring). 2026 Jul 12. doi: 10.1002/oby.70203. Online ahead of print. Obesity (Silver Spring). 2026. PMID: 42438123 Review.
Incretin mimetics are increasingly prescribed for the treatment of overweight and obesity, resulting not only in significant weight reduction but also co-occurring improvements in cardiovascular health and quality of life. Incretin mimetic use among older adults is expecte …
Incretin mimetics are increasingly prescribed for the treatment of overweight and obesity, resulting not only in significant weight reductio …
LEARNER: A Transfer Learning Method for Low-Rank Matrix Estimation.
McGrath S, Zhu C, O'Dea R, Guo M, Duan R. McGrath S, et al. Stat Med. 2026 Jul;45(15-17):e70669. doi: 10.1002/sim.70669. Stat Med. 2026. PMID: 42438120
Low-rank matrix estimation is a fundamental problem in statistics and machine learning with applications across biomedical sciences, including genetics, medical imaging, drug discovery, and electronic health record data analysis. In the context of heterogeneous data genera …
Low-rank matrix estimation is a fundamental problem in statistics and machine learning with applications across biomedical sciences, includi …
Atherosclerotic Cardiovascular Disease and Cancer.
Amend A, Horstmann H, Lavine KJ, Giannarelli C, Moore KJ. Amend A, et al. Immunol Rev. 2026 Jul;340(1):e70141. doi: 10.1111/imr.70141. Immunol Rev. 2026. PMID: 42438017 Review.
Social network characteristics and cognitive function, decline, and mortality: A joint modeling approach.
Chen R, Posis AIB, Pederson AM, Wang J, Hirst AK, Rojas-Saunero LP, Kim YJ, Haneuse S, Peterson R, Mungas D, Torres JM, Mayeda ER, Gilsanz P, Whitmer RA, Corrada MM, Glymour MM. Chen R, et al. Alzheimers Dement. 2026 Jul;22(7):e71600. doi: 10.1002/alz.71600. Alzheimers Dement. 2026. PMID: 42437967
INTRODUCTION: Maintaining social relationships is challenging in advanced old age due to frequent changes in social networks. ...Social networks did not predict cognitive decline or mortality. DISCUSSION: Among adults aged 90+, social networks were lin …
INTRODUCTION: Maintaining social relationships is challenging in advanced old age due to frequent changes in social networks. …
Nuclear dysfunction in aging and neurodegeneration.
Aday A, Tiller J, Melukote A, Walton ZC, King A, Castillo L, Kayed R, Montalbano M. Aday A, et al. Alzheimers Dement. 2026 Jul;22(7):e71657. doi: 10.1002/alz.71657. Alzheimers Dement. 2026. PMID: 42437963 Review.
Examining Risk Factors for Pressure Injury Development Among Nursing Home Residents: A Retrospective Study.
Brooks KR, Alderden J, Horn SD, Sharkey PD, Kennerly SM, Yap TL. Brooks KR, et al. J Clin Nurs. 2026 Jul 12. doi: 10.1111/jocn.70369. Online ahead of print. J Clin Nurs. 2026. PMID: 42437704
Clinical mobility assessments remain essential but gain value when integrated with physiological markers. As electronic health record use increases in nursing homes, future research can leverage these data to develop targeted interventions. ...
Clinical mobility assessments remain essential but gain value when integrated with physiological markers. As electronic health record …
Structure-Activity Relationship Analysis and hERG Liability Assessment of Second-Generation Antibiofilm Compounds Active Against Salmonella.
Sorge A, Bennett AN, Gregory SE, Cole AL, Woolard KJ, Nemeth AM, Crow AH, Melander RJ, Gunn JS, Melander C. Sorge A, et al. ChemMedChem. 2026 Jul 14;21(13):e70363. doi: 10.1002/cmdc.70363. ChemMedChem. 2026. PMID: 42437701
Lead antibiofilm compounds were tested for human ether-a-go-go-related gene (hERG) channel inhibition, from which we report new lead compounds with improved antibiofilm activity and reduced hERG channel inhibition....
Lead antibiofilm compounds were tested for human ether-a-go-go-related gene (hERG) channel inhibition, from which we report new lead …
Deep learning models for cell cycle phase prediction from single-cell RNA sequencing data.
Akhter H, Piktel D, Gibson LF, Hu G, Adjeroh DA. Akhter H, et al. Brief Bioinform. 2026 Jul 3;27(4):bbag342. doi: 10.1093/bib/bbag342. Brief Bioinform. 2026. PMID: 42437449 Free PMC article.
Models were trained using consensus phase labels derived from four established tools (CellCycleScore, ccAFv2, Revelio, and Tricycle) applied to single-cell gene expression datasets representing diverse biological contexts, including a human leukemia cell line (REH), periph …
Models were trained using consensus phase labels derived from four established tools (CellCycleScore, ccAFv2, Revelio, and Tricycle) applied …
Chemoradiation (CCRT) Effects on Head and Neck Muscles: Insights Into CCRT-Induced Dysphagia.
Amin MR, Gould M, Severa E, Kravietz A, Achlatis S, Tesema N, Best KA, Garber D, Strum D, Yang J, Johnson AM. Amin MR, et al. Laryngoscope. 2026 Jul 12. doi: 10.1002/lary.70722. Online ahead of print. Laryngoscope. 2026. PMID: 42437408
CCRT was associated with significantly reduced muscle fiber size in human specimens. Neuromuscular junction presence and morphology in rats were not affected. CONCLUSION: This translational study demonstrates significant alterations in head and neck muscles in both a rat m …
CCRT was associated with significantly reduced muscle fiber size in human specimens. Neuromuscular junction presence and morphology i …
Economic burden of adult mild traumatic brain injury in the United States: a scoping review of healthcare-related charges and costs.
Ran KR, Caldwell DJ, Tarapore PE, Halabi C, Aabedi AA, Velasco MCV, Saigal R, DiGiorgio AM, Huang MC, Hinson HE, Manley GT, Yue JK. Ran KR, et al. Lancet Reg Health Am. 2026 Jul 6;62:101558. doi: 10.1016/j.lana.2026.101558. eCollection 2026 Oct. Lancet Reg Health Am. 2026. PMID: 42437268 Free PMC article. Review.
We synthesized direct healthcare charges and costs associated with mTBI in the United States (U.S.). A PubMed search through October 14, 2025 identified primary studies reporting direct healthcare-related charges or costs among adults with mTBI. All estimates were s …
We synthesized direct healthcare charges and costs associated with mTBI in the United States (U.S.). A PubMed search through O …
Following Severe Pediatric Malaria, Epilepsy Screening Is Needed Even Among Children Without Coma: Findings From a Prospective Cohort Study.
Patel AA, Nishat S, Joshi RB, Mwanza S, Kasolo J, Masempela A, Musakanya T, Mwale T, Nambeye V, Nyirongo R, Tembo RG, O'Brien N, Seydel KB, Cortina C, Zhang B, Mazumdar M, Rotenberg A, Birbeck GL. Patel AA, et al. J Cent Nerv Syst Dis. 2026 Jul 10;18:11795735261467520. doi: 10.1177/11795735261467520. eCollection 2026. J Cent Nerv Syst Dis. 2026. PMID: 42436689 Free PMC article.
Rigorous projects and grants integrating human-centered design and implementation science: 8 tips for success.
Aung T, Osterhage KP, Graham AK, Proctor EK, Lyon AR, Munson SA. Aung T, et al. Implement Sci Commun. 2026 Jul 11. doi: 10.1186/s43058-026-01035-5. Online ahead of print. Implement Sci Commun. 2026. PMID: 42436554 Free article.
BACKGROUND: Researchers and funders increasingly see potential for integrating human-centered design (HCD) and implementation science (IS) approaches to enhance the design and uptake of health interventions and implementation strategies. ...Our considerations are in …
BACKGROUND: Researchers and funders increasingly see potential for integrating human-centered design (HCD) and implementation science …
Preliminary trial findings from Harvest Share: a cost-offset community supported agriculture model to improve diet in New York City.
LeCroy MN, Cardenas L, Chan SWC, Scherer M, Dolotina B, Lanza DV, Dowd R, Hughes M, Mei S, Barth K, Gregoire M, Rodriguez Gil AI, DeDominicis M, Acevedo M, Rodriguez A, Kourousias L, Cheng M, Wu M, Guzman J, Belli HM, Barajas-Gonzalez RG, Đoàn LN, Yi SS. LeCroy MN, et al. Int J Behav Nutr Phys Act. 2026 Jul 11. doi: 10.1186/s12966-026-01906-z. Online ahead of print. Int J Behav Nutr Phys Act. 2026. PMID: 42436486 Free article.
Mixed effect linear regression models were used to examine the impact of Harvest Share on primary (Veggie Meter score) and secondary outcomes (diet and social variables). Significant associations were based on the group (CSA vs. CC) by time (pre vs. post) interaction term. …
Mixed effect linear regression models were used to examine the impact of Harvest Share on primary (Veggie Meter score) and secondary outcome …
CDK8 remodels the tumor microenvironment and promotes resistance to KRASG12D inhibitors and daraxonrasib in PDAC.
McAndrews KM, Mahadevan KK, Li B, Comptdaer AM, Sockwell AM, Morse SJ, Kelly PJ, Patel SI, Kirtley ML, Moreno Diaz BA, Lyu H, Peng DH, Khazaei S, Schalck A, Zhou X, Sugimoto H, Bickert AA, Sthanam LK, Taylor MR, Kumbhar SV, Arian KA, Barekatain Y, Paradiso F, Guerrero PA, Bernard V, Sobhani N, Camacho-Acevedo AN, Bornes KE, Tran PT, Maitra A, Heffernan TP, Kalluri R. McAndrews KM, et al. EMBO J. 2026 Jul 11. doi: 10.1038/s44318-026-00854-5. Online ahead of print. EMBO J. 2026. PMID: 42436354 Free article.
AURKA regulates LGR5 in response to Helicobacter Pylori infection by modulating its deubiquitination.
Gomaa A, Maacha S, Soutto M, Giordano S, Bhat N, Kumar S, McDonald OG, El-Rifai W. Gomaa A, et al. Cell Death Differ. 2026 Jul 11. doi: 10.1038/s41418-026-01810-w. Online ahead of print. Cell Death Differ. 2026. PMID: 42436338
We analyzed publicly available datasets, gastric cancer cell lines, patient-derived organoids and xenografts (PDOs and PDXs), mouse models, and de-identified human tissue samples. We found a strong association between AURKA and LGR5 expression levels in gastric cancer tiss …
We analyzed publicly available datasets, gastric cancer cell lines, patient-derived organoids and xenografts (PDOs and PDXs), mouse models, …
Immigration-Related Sociopolitical Stress, Mental Health, and Tobacco Use Among Mexican American College Students.
Schwartz SJ, Marti CN, Talavera-Garza L, North CE, Yang Q, Murthy D, Arora S, Wilkinson AV, Loukas A. Schwartz SJ, et al. J Immigr Minor Health. 2026 Jul 11. doi: 10.1007/s10903-026-01958-0. Online ahead of print. J Immigr Minor Health. 2026. PMID: 42436266
Sociopolitical stress associated with the policies and rhetoric coming from recent U.S. presidential administrations is of particular concern vis-a-vis Hispanic individuals, who have been disproportionately targeted for detention and deportation. ...Intervention and …
Sociopolitical stress associated with the policies and rhetoric coming from recent U.S. presidential administrations is of par …
Microbiome-derived queuine vitamers underlie tyrosine metabolism and predator avoidance in mosquito larvae.
Kelley M, Rathore S, Chandrasegaran K, Herbert C, Sabile CEG, Wood T, Joves J, Palacios A, Hamal B, Tompkin J, Susanto E, Uhran M, Ledezma-Ramírez A, Chen SC, Singh K, Rust R, Solorio MM, Khalid MS, Mitra AT, Vinauger C, Buschbeck EK, Limbach PA, Benoit JB. Kelley M, et al. Commun Biol. 2026 Jul 11. doi: 10.1038/s42003-026-10537-w. Online ahead of print. Commun Biol. 2026. PMID: 42436262 Free article.
Neurobiological subtypes in alcohol use disorder and their phenotypic and clinical profiles.
Brucar LR, Rawls E, Zilverstand A. Brucar LR, et al. Mol Psychiatry. 2026 Jul 11. doi: 10.1038/s41380-026-03748-4. Online ahead of print. Mol Psychiatry. 2026. PMID: 42436260
Participants with complete resting-state functional MRI (rs-fMRI), phenotypic and clinical data from the Human Connectome Project were included (N = 668; 58% Female; 22% AUD [mild AUD: n = 109; moderate-severe AUD: n = 38], 40% Female within AUD). ...
Participants with complete resting-state functional MRI (rs-fMRI), phenotypic and clinical data from the Human Connectome Project wer …
Passive early screening for Alzheimer's disease and related dementias using EHR comorbidity patterns.
Onishchenko D, Mastrianni JA, Chattopadhyay I. Onishchenko D, et al. NPJ Digit Med. 2026 Jul 11. doi: 10.1038/s41746-026-02954-2. Online ahead of print. NPJ Digit Med. 2026. PMID: 42436226 Free article.
The Zero-burden Risk Assessment (ZeBRA) is an AI-driven score that predicts incident ADRD up to a decade before diagnosis using only routine electronic health record (EHR) data, without laboratory tests, imaging, or questionnaires. Trained on 487,989 cases and 12,483,718 c …
The Zero-burden Risk Assessment (ZeBRA) is an AI-driven score that predicts incident ADRD up to a decade before diagnosis using only routine …
Super-resolution atlas of SARS-CoV-2 infection reveals protease-dependent organelle maturation, dsRNA landscapes, and intracellular structural proteins.
Andronov L, Han M, Balaji A, Zhu Y, Qi LS, Moerner WE. Andronov L, et al. Nat Commun. 2026 Jul 11. doi: 10.1038/s41467-026-75289-x. Online ahead of print. Nat Commun. 2026. PMID: 42436145 Free article.
We built a multi-color super-resolution atlas of SARS-CoV-2 RNA, non-structural and structural proteins in infected human cells, combining 3D single-molecule localization with radial and angular pair-correlation analysis. ...
We built a multi-color super-resolution atlas of SARS-CoV-2 RNA, non-structural and structural proteins in infected human cells, comb …
Essential role for the urothelial plaque in Gram-negative urinary tract infections.
Jackson AR, Li B, El-Harakeh M, Cortado H, Gupta S, Ballash G, Ching CB, Wang X, Becknell B. Jackson AR, et al. Sci Rep. 2026 Jul 11. doi: 10.1038/s41598-026-59987-6. Online ahead of print. Sci Rep. 2026. PMID: 42436141 Free article.
Notable study limitations include the potential that observations made in mouse models are associative rather than causal and that our conclusions may not fully apply to human UTI. While our findings strengthen the rationale for targeted therapies that disrupt UPEC-plaque …
Notable study limitations include the potential that observations made in mouse models are associative rather than causal and that our concl …
The landscape of plasma proteomic links to human organ imaging.
Fan Z, Chirinos J, Yang X, Shu J, Li Y, O'Brien JM, Witschey W, Rader DJ, Gur R, Zhao B. Fan Z, et al. Nat Commun. 2026 Jul 11. doi: 10.1038/s41467-026-74715-4. Online ahead of print. Nat Commun. 2026. PMID: 42436130 Free article.
Plasma protein levels provide important insights into human disease, yet a comprehensive assessment of plasma proteomics across organs is lacking. ...Our study shows that integrating plasma proteomics with multi-organ imaging provides a comprehensive pan-organ imaging-prot …
Plasma protein levels provide important insights into human disease, yet a comprehensive assessment of plasma proteomics across organ …
Patient-derived model capturing hypoxia and extracellular matrix remodelling of immunologically cold high-grade serous tumours.
Plesselova S, Axemaker H, Calar K, Isaiah O, Wollman J, Bhattacharya S, Gnimpieba EZ, Fink DM, Wang C, Sumanasiri H, Thiel KW, Bell M, de la Puente P. Plesselova S, et al. Nat Commun. 2026 Jul 11. doi: 10.1038/s41467-026-75262-8. Online ahead of print. Nat Commun. 2026. PMID: 42436127 Free article.
Cancer cells are co-cultured with cancer-associated fibroblasts within human plasma-3D matrices or grown on decellularized human ovaries. Immune cells are either included within the 3D constructs to study multi-cellular interactions or challenged to infiltrate the m …
Cancer cells are co-cultured with cancer-associated fibroblasts within human plasma-3D matrices or grown on decellularized human
An analysis of the readability of Gynecologic Cancer patient education materials.
Dillon BS, Hood O, Chanda S, Madill M, Tessier KM, Erickson BK, O'Shea A. Dillon BS, et al. Gynecol Oncol. 2026 Jul 11;211:142-147. doi: 10.1016/j.ygyno.2026.07.002. Online ahead of print. Gynecol Oncol. 2026. PMID: 42435633
OBJECTIVE: The National Institute of Health (NIH) and American Medical Association (AMA) recommend patient education material be written at or below a 7th grade reading level. The objective of this study was to assess the reading level of gynecologic cancer p …
OBJECTIVE: The National Institute of Health (NIH) and American Medical Association (AMA) recommend patient education ma …
Abnormal activation of the mineralocorticoid receptor in the aldosterone-sensitive distal nephron contributes to fructose-induced salt-sensitive hypertension.
Zhang R, Kim N, Shi S, Jadhav DA, Brostek A, Forester BR, Shukla R, Qu C, Kramer B, Moss FJ, Garvin JL, Kleyman TR, Gonzalez-Vicente A. Zhang R, et al. Am J Physiol Renal Physiol. 2026 Jul 11. doi: 10.1152/ajprenal.00099.2025. Online ahead of print. Am J Physiol Renal Physiol. 2026. PMID: 42435416 Free article.
Changes in Life Expectancy After Stroke Among Americans Aged 50 and Above by Sex, 1996-2018.
Bramajo O, Chakraborty M, Lisabeth L, Mehta N. Bramajo O, et al. J Am Geriatr Soc. 2026 Jul 11. doi: 10.1111/jgs.70585. Online ahead of print. J Am Geriatr Soc. 2026. PMID: 42435310
METHODS: Using longitudinal data from the nationally representative Health and Retirement Study (1996-2018; 39,084 individuals, 225,316 person-wave observations), in which stroke status is self-reported, we computed life expectancy at Age 50 (LE50) for those with and witho …
METHODS: Using longitudinal data from the nationally representative Health and Retirement Study (1996-2018; 39,084 individuals, 225,3 …
No association between alcohol consumption and hip osteoarthritis: a diverse national analysis of 87,585 adults from the "All of Us" research program.
Patel SV, Khan ST, Brahmbhatt S, Deren ME, Piuzzi NS. Patel SV, et al. Clin Rheumatol. 2026 Jul 11. doi: 10.1007/s10067-026-08279-5. Online ahead of print. Clin Rheumatol. 2026. PMID: 42435290
Utilizing data from 87,585 adults in the NIH "All of Us" Research Program, this is the first study to analyze this relationship in a large, nationally representative population. ...
Utilizing data from 87,585 adults in the NIH "All of Us" Research Program, this is the first study to analyze this relationship in a …
Impact of Institutional Review Board Type and Food and Drug Administration Diversity Action Plan Draft Guidance on Demographics of Participants Enrolled Clinical Trials Conducted from 2020 to 2024.
Wheeler K, Ervin AM, Elrod M. Wheeler K, et al. J Empir Res Hum Res Ethics. 2026 Jul 11:15562646261460666. doi: 10.1177/15562646261460666. Online ahead of print. J Empir Res Hum Res Ethics. 2026. PMID: 42434903
We assessed participant representation in phase 3 clinical trials registered on clinicaltrials.gov that were conducted in the U.S. between 2020 and 2024. From the 211 clinical trials analyzed, most relied on commercial IRBs (23.2%). ...When assessing the impact of t …
We assessed participant representation in phase 3 clinical trials registered on clinicaltrials.gov that were conducted in the U.S
Direct effects of glucagon-like Peptide-1 receptor agonists on mitochondrial function in human-derived in vitro models: A systematic review and meta-analysis.
Greenblatt ZL, Tork A, Cruz I, Fausak ED, Tran HA, Krovidy M, Giulivi C. Greenblatt ZL, et al. Metabol Open. 2026 Jul 2;31:100484. doi: 10.1016/j.metop.2026.100484. eCollection 2026 Sep. Metabol Open. 2026. PMID: 42434480 Free PMC article.
To our knowledge, this is the first systematic review and meta-analysis examining direct mitochondrial effects of GLP-1 RAs in human-derived in vitro models. Of 1547 records identified (1203 screened after deduplication), 17 studies met the criteria, and only 11 contribute …
To our knowledge, this is the first systematic review and meta-analysis examining direct mitochondrial effects of GLP-1 RAs in human- …
Cytotoxicity Assessment and Indentation Size Effect of Low-Cost Experimental Implant Alloys.
Nkosi NV, Essa D, Moalodi AC, Lawal J, Choonara Y, Klenam D, Bodunrin MO. Nkosi NV, et al. ACS Mater Au. 2026 Apr 9;6(4):808-819. doi: 10.1021/acsmaterialsau.6c00008. eCollection 2026 Jul 8. ACS Mater Au. 2026. PMID: 42434470 Free PMC article.
In parallel, in vitro cytotoxicity was evaluated using NIH-3T3 fibroblast cells following the ISO 10993-5 guidelines. The experimental titanium alloys exhibited pronounced ISE behavior and the highest GND densities, indicating enhanced resistance to plastic deformation at …
In parallel, in vitro cytotoxicity was evaluated using NIH-3T3 fibroblast cells following the ISO 10993-5 guidelines. The experimenta …
Comparative evaluation of short vs. long needles in deep ultrasound-guided pharmacopuncture for acute low back pain: study protocol.
Kim K, Lee YU, Kwon R, Chu H, Park S, Hong HJ, Lee Y, Kwon J, Song J, Kwon S, Leem J, Kim CH. Kim K, et al. Front Med (Lausanne). 2026 Jun 24;13:1822731. doi: 10.3389/fmed.2026.1822731. eCollection 2026. Front Med (Lausanne). 2026. PMID: 42434008 Free PMC article.
CLINICAL TRIAL REGISTRATION: https://cris.nih.go.kr/cris/search/detailSearch.do?seq=32507&search_page=L&search_lang=&class_yn=....
CLINICAL TRIAL REGISTRATION: https://cris.nih.go.kr/cris/search/detailSearch.do?seq=32507&search_page=L&search_lang=&clas …
The Future of the HIV Response: Sustaining Progress in an era of Political Uncertainty and Scientific Opportunity.
Warren M. Warren M. Am J Reprod Immunol. 2026 Jul;96(1):e70287. doi: 10.1111/aji.70287. Am J Reprod Immunol. 2026. PMID: 42433152 Free PMC article. Review.
Drawing on recent advances in HIV prevention and treatment, as well as massive disruptions and cuts in both global health programs, including PEPFAR, and biomedical research funding under the new US Presidential Administration, the paper identifies key priorities for the n …
Drawing on recent advances in HIV prevention and treatment, as well as massive disruptions and cuts in both global health programs, i …
A Data-Driven Medication Regimen Complexity Score for Critically Ill Patients: MRC-ICU 2.0.
Zhao B, Shen Y, Henry K, Devlin JW, Murphy DJ, Smith SE, Murray B, Rowe S, Sikora A. Zhao B, et al. Pharmacotherapy. 2026 Aug;46(8):e70185. doi: 10.1002/phar.70185. Pharmacotherapy. 2026. PMID: 42433012 Free PMC article.
METHODS: This was a retrospective, observational cohort study of adults admitted to an ICU between 2015 and 2023 at two academic health systems. Machine learning-based methods, including Principal Component Analysis and Random Forest, were used to create an updated MRC-ICU …
METHODS: This was a retrospective, observational cohort study of adults admitted to an ICU between 2015 and 2023 at two academic health
Suppression of the myofibroblastic cancer-associated fibroblast phenotype to enhance anti-PD-1 response.
Johnson KA, Lippert AEL, Cornelio A, Gadalla Y, Shen X, Kraus SG, Emmerich PB, Field AM, Steimle AK, Pasch CA, Dinh HQ, Zhang W, Matkowskyj KA, Deming DA. Johnson KA, et al. J Exp Clin Cancer Res. 2026 Jul 10. doi: 10.1186/s13046-026-03779-3. Online ahead of print. J Exp Clin Cancer Res. 2026. PMID: 42432797 Free article.
CAF markers were validated and compared to clinical characteristics using patient-derived CAF cultures, fixed human CRC samples, and publicly available RNA sequencing data. Therapeutics were prioritized for their potential to inhibit the myCAF phenotype and nilotinib was s …
CAF markers were validated and compared to clinical characteristics using patient-derived CAF cultures, fixed human CRC samples, and …
Association of rapamycin treatment with the modulation of purine metabolism, reduced microglial inflammatory responses, improved mitochondrial energy metabolism, and alleviation of fatigue symptoms in ME/CFS subjects: pilot findings from phase-II observational study.
Gile B, Bulbule S, Toriola MA, Ruan BT, Marium S, Benko A, Grach S, Mueller M, Bateman L, Bell J, Yellman B, Berner J, Chheda B, Kaufman D, Gottschalk G, Roy A. Gile B, et al. J Transl Med. 2026 Jul 10. doi: 10.1186/s12967-026-08575-3. Online ahead of print. J Transl Med. 2026. PMID: 42432754 Free article.
Lower plasma resolvin D1 level and greater sputum eosinophilia characterize a cluster of severe asthma patients.
Duvall MG, Sun Y, Mirzakhani H, Pons S, Dorazio MH, Chiha T, Lu Z, Phillips BR, Aronica MA, Bleecker ER, Castro M, Comhair SA, Denlinger LC, Erzurum SC, Fahy JV, Hastie AT, Jarjour NN, Khatri PK, Meyers DA, Moore WC, Ortega VE, Phipatanakul W, Seibold MA, Sumino K, Wenzel SE, Woodruff PG, Mauger DT, Israel E, Levy BD. Duvall MG, et al. Respir Res. 2026 Jul 10. doi: 10.1186/s12931-026-03790-4. Online ahead of print. Respir Res. 2026. PMID: 42432742 Free article.
Combining multiplexed functional data to improve variant classification.
Calhoun JD, Dawood M, Rowlands CF, Fayer S, Radford EJ, McEwen AE, Tejura M, Turnbull C, Spurdle AB, Starita LM, Jagannathan S. Calhoun JD, et al. Genome Med. 2026 Jul 11. doi: 10.1186/s13073-026-01715-w. Online ahead of print. Genome Med. 2026. PMID: 42432739 Free article.
Visualizing stigma and HIV service engagement: a participatory approach using causal loop diagrams.
Chen M, Baral S, Murray SM, Jenness SM, Lucas IL, Sanchez T, Atkins K, Lyons C, Yu Y, Alicea-Jorgensen K, Robinson KC, Igusa T, Rao A. Chen M, et al. BMC Public Health. 2026 Jul 10. doi: 10.1186/s12889-026-28414-w. Online ahead of print. BMC Public Health. 2026. PMID: 42432567 Free article.
RESULTS: The resulting CLDs highlighted interrelated feedback loops across three key domains: (1) personal health attitudes and care navigation, (2) provision of quality services, and (3) community influences on HIV-related health and care. Anticipated and in …
RESULTS: The resulting CLDs highlighted interrelated feedback loops across three key domains: (1) personal health attitudes and care …
Unique features of peer relationships in specific developmental periods predict borderline personality disorder and major depressive disorder in late adolescence.
Naeem S, Gilbert K, Vogel AC, Huntington C, Tillman R, Barch DM, Luby J, Whalen DJ. Naeem S, et al. BMC Psychiatry. 2026 Jul 10. doi: 10.1186/s12888-026-08372-8. Online ahead of print. BMC Psychiatry. 2026. PMID: 42432563 Free article.
Louis region (N = 189; 50.8% female; 54.0% White, 34.4% Black), we examined how parent-reported bullying victimization, peer acceptance, and relational aggression- assessed up to 8 times via the MacArthur Health and Behavior Questionnaire (HBQ-P) across early childhood (ag …
Louis region (N = 189; 50.8% female; 54.0% White, 34.4% Black), we examined how parent-reported bullying victimization, peer acceptance, and …
Motivations and Barriers to Sustained PrEP Use Among Men in Buffalo City Metro, South Africa: A Qualitative Study.
Smith PJ, Daniels J, Bekker LG, Medina-Marino A. Smith PJ, et al. AIDS Behav. 2026 Jul 11. doi: 10.1007/s10461-026-05239-7. Online ahead of print. AIDS Behav. 2026. PMID: 42432402
Structural conditions further shaped engagement: men preferred convenient community-based PrEP services, while anxiety surrounding routine HIV testing was described as discouraging for men more broadly, although many participants reported that their own concerns diminished …
Structural conditions further shaped engagement: men preferred convenient community-based PrEP services, while anxiety surrounding ro …
Anti-LAG-3 with or without anti-PD-1 in recurrent glioblastoma: a phase 1 trial.
Lim M, Ye X, Piotrowski AF, Desai A, Ahluwalia MS, Walbert T, Lesser G, Ellingson BM, Peereboom DM, Fisher JD, Desideri S, Jackson C, Pant A, Jain A, Verma R, Oberlton B, Piyadasa H, Bettegowda C, Engle L, Taube J, Bendall SC, Choi J, Drappatz J, Lieberman FS, Kleinberg LR, Pardoll DM, Nabors LB, Wen PY, Grossman SA. Lim M, et al. Nat Med. 2026 Jul 10. doi: 10.1038/s41591-026-04475-7. Online ahead of print. Nat Med. 2026. PMID: 42432293
Age-independent immune subtypes in type 1 diabetes exhibit distinct post-onset progression rates and immunotherapeutic responses.
Bedrat A, Truchan NA, Pant T, Jia S, Roethle MF, Chen YG, Lin CW, Hessner MJ. Bedrat A, et al. Diabetologia. 2026 Jul 11. doi: 10.1007/s00125-026-06794-3. Online ahead of print. Diabetologia. 2026. PMID: 42432282
DATA AVAILABILITY: All microarray gene expression data files have been deposited at The National Center for Biotechnology Information Gene Expression Omnibus (accession no. GSE302205)....
DATA AVAILABILITY: All microarray gene expression data files have been deposited at The National Center for Biotechnology Information …
FMR1 gene therapy restores translationally relevant phenotypes in a mouse model for fragile X syndrome.
Lacher RK, Henson K, Wathen LN, Jones C, Arnold T, Rice MR, Carles HM, White AR, Ramsuchit E, Murrey D, Raig R, Fisher A, Bucher K, Westerkamp GC, Fritz AL, Gollaway BM, Piloto S, Dismuke D, Robinson JE, Williams MT, Vorhees CV, De Silva EK, Tiwari D, Erickson CA, Pedapati EV, Gross C. Lacher RK, et al. Gene Ther. 2026 Jul 10. doi: 10.1038/s41434-026-00630-4. Online ahead of print. Gene Ther. 2026. PMID: 42432256
UbiDash: A UPS proteomic atlas for tissue-aware degrader design.
González-Robles TJ, Sastourné P, Triola M, Khan M, Bartha Á, Estrada J, Soto-Feliciano YM, Neel BG, Fenyö D, Pagano M, Ruggles KV. González-Robles TJ, et al. Cell Death Differ. 2026 Jul 10. doi: 10.1038/s41418-026-01791-w. Online ahead of print. Cell Death Differ. 2026. PMID: 42432252
Establishment and functional analysis of an inducible Apoc2-knockout mouse model to investigate the role of Apoc2 in normal hematopoiesis.
Zhang X, Chandwani R, Pospiech M, Meng Y, Dhuri K, Ali A, Thakker B, Kadam SM, Zhu W, Xiao Y, Sviridov D, Wolska A, Remaley AT, Alachkar H. Zhang X, et al. Lab Anim (NY). 2026 Jul 10. doi: 10.1038/s41684-026-01748-z. Online ahead of print. Lab Anim (NY). 2026. PMID: 42432158
RNA-sequencing analysis of bone marrow samples from the Apoc2-KO group identified four significantly downregulated genes and five upregulated genes, including Gm16867, which is orthologous to the human SLC25A37 gene involved in mitochondrial iron homeostasis. Gene set enri …
RNA-sequencing analysis of bone marrow samples from the Apoc2-KO group identified four significantly downregulated genes and five upregulate …
Comprehensive multi-omic dissection and AI-prioritized target identification in inverted papilloma-associated sinonasal squamous cell carcinoma.
Singh A, Korzinkin M, Sarkisova V, Vergasova E, Rosenberg AJ, Suresh K, Mishra V, Miao Y, Shen L, Smolik J, Veviorskiy A, Pun FW, Cheng X, Wing C, Pinto J, Low CM, Lingen MW, Rooper L, Pearson AT, Vokes EE, Liu X, London N, Zhavoronkov A, Agrawal N, Izumchenko E. Singh A, et al. NPJ Precis Oncol. 2026 Jul 10. doi: 10.1038/s41698-026-01599-4. Online ahead of print. NPJ Precis Oncol. 2026. PMID: 42432132 Free article.
Effects of HIV status and vaccination on long COVID conditions within an integrated health care system.
Horberg MA, Jefferson C, Watson E, Kim S, Deneal AN, Gebo KA, Hogan BC, Humes E, Althoff KN. Horberg MA, et al. Commun Med (Lond). 2026 Jul 10. doi: 10.1038/s43856-026-01761-w. Online ahead of print. Commun Med (Lond). 2026. PMID: 42432030 Free article.
Some people who get COVID-19 develop long-term health problems, known as Long COVID or post COVID conditions (PCC), which can appear one to four months after infection. ...
Some people who get COVID-19 develop long-term health problems, known as Long COVID or post COVID conditions (PCC), which can appear …
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