R01 DK072381/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1998	1
2001	1
2005	2
2006	3
2007	7
2008	11
2009	16
2010	19
2011	10
2012	20
2013	14
2014	20
2015	30
2016	23
2017	13
2018	17
2019	11
2020	6
2021	17
2022	10
2023	13
2024	11
2025	9
2026	0

1

In vivo chemical reprogramming is associated with a toxic accumulation of lipid droplets hindering rejuvenation.

Mitchell W, de Magalhães CG, Tyshkovskiy A, Uchida Y, Goeminne LJE, Ichimura T, Ng EL, Bonventre JV, Gladyshev VN. Mitchell W, et al. bioRxiv [Preprint]. 2025 Jun 27:2025.06.25.661123. doi: 10.1101/2025.06.25.661123. bioRxiv. 2025. Update in: Aging Cell. 2026 Feb;25(2):e70390. doi: 10.1111/acel.70390. PMID: 40667171 Free PMC article. Updated. Preprint.

2

Circulating Proteins for Prediction of Kidney Disease Progression and Cardiovascular Outcomes: Individual Participant Data Meta-Analysis of Four Cohorts.

Lopez-Silva C, Surapaneni A, Coresh J, Chen TK, Schlosser P, Rhee EP, Waikar SS, Schmidt IM, Deo R, Ganz P, Dubin R, Ramachandran VS, Kimmel PL, Schrauben SJ, Parikh CR, Bonventre JV, Dobre M, Rao PS, Ricardo AC, Weir MR, Grams ME; CRIC Study Investigators. Lopez-Silva C, et al. Am J Nephrol. 2025 Jun 30:1-12. doi: 10.1159/000547138. Online ahead of print. Am J Nephrol. 2025. PMID: 40587944 Free PMC article.

3

The distal nephron biomarkers associate with diabetic kidney disease progression.

Tamargo CL, Coca SG, Thiessen Philbrook H, Hu DG, Ix JH, Shlipak MG, Fried LF, Gutierrez OM, Waikar SS, Schrauben SJ, Schelling JR, Ganz P, Kimmel PL, Greenberg JH, Deo R, Takakura A, Vasan RS, Bonventre JV, Parikh CR. Tamargo CL, et al. JCI Insight. 2025 Jun 23;10(12):e186836. doi: 10.1172/jci.insight.186836. eCollection 2025 Jun 23. JCI Insight. 2025. PMID: 40548378 Free PMC article. Clinical Trial.

4

Self-Assembly of Nanogold Triplets on Trimeric Viral Proteins for Infectious Disease Diagnosis.

Liu W, Soliman A, Emam HE, Zhang J, Bonventre JV, Lee LP, Nasr ML. Liu W, et al. ACS Nano. 2025 May 13;19(18):17514-17524. doi: 10.1021/acsnano.4c17685. Epub 2025 May 5. ACS Nano. 2025. PMID: 40323304

5

Breast cancer gene-1 (BRCA1) potentiates maladaptive repair after kidney injury.

Ajay AK, Akinfolarin AA, Gifford CC, Sabbisetti VS, Bonventre JV. Ajay AK, et al. J Exp Med. 2025 Jun 2;222(6):e20231107. doi: 10.1084/jem.20231107. Epub 2025 Mar 28. J Exp Med. 2025. PMID: 40152784 Free PMC article.

6

Transplantation of human kidney organoids elicited a robust allogeneic response in a humanized mouse model.

Mon-Wei Yu S, Choi JY, Kady J, De Cos M, Wong JS, King E, Younis N, Al Rahy N, Al Chaar S, Djebli H, Eskandari S, Samuel S, Merhej T, Sukumar N, Lin JR, Chen JY, Xu Y, Santagata S, Weins A, Yeung M, Cravedi P, Campbell KN, Lemos D, Bonventre JV, Brehm MA, Azzi J. Mon-Wei Yu S, et al. Kidney Int. 2025 Jun;107(6):1011-1016. doi: 10.1016/j.kint.2025.02.027. Epub 2025 Mar 22. Kidney Int. 2025. PMID: 40127865

7

Defining Kidney Health Dimensions and Their Associations with Adverse Outcomes in Persons with Diabetes and CKD.

Peschard VG, Scherzer R, Estrella MM, Sarnak MJ, Ascher SB, Lash J, Bonventre JV, Greenberg JH, Gutierrez OM, Schelling JR, Katz R, Cheung KL, Levitan EB, Schrauben SJ, Cushman M, Ilori TO, Parikh CR, Kimmel PL, Rao PS, Taliercio JJ, Sondheimer J, Shulman R, Coca SG, Chen J, Ramachandran VS, Ix JH, Shlipak MG; CKD Biomarkers Consortium and the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators. Peschard VG, et al. Clin J Am Soc Nephrol. 2025 May 1;20(5):665-675. doi: 10.2215/CJN.0000000676. Epub 2025 Mar 14. Clin J Am Soc Nephrol. 2025. PMID: 40085155

8

Uranium exposure and kidney tubule biomarkers in the Multi-Ethnic Study of Atherosclerosis (MESA).

Anderson WA, Domingo-Relloso A, Galvez-Fernandez M, Schilling K, Glabonjat RA, Basu A, Nigra AE, Gutierrez OM, Scherzer R, Goldsmith J, Sarnak MJ, Bonventre JV, Kimmel PL, Vasan RS, Ix JH, Shlipak MG, Navas-Acien A. Anderson WA, et al. Environ Res. 2025 Apr 15;271:121060. doi: 10.1016/j.envres.2025.121060. Epub 2025 Feb 6. Environ Res. 2025. PMID: 39922262 Free PMC article.

9

Biomarker Panels for Discriminating Risk of CKD Progression in Children.

Greenberg JH, Abraham AG, Xu Y, Schelling JR, Coca SG, Schrauben SJ, Wilson FP, Waikar SS, Vasan RS, Gutiérrez OM, Shlipak MG, Ix JH, Warady BA, Kimmel PL, Bonventre JV, Parikh CR, Denburg M, Furth S; CKD Biomarkers Consortium. Greenberg JH, et al. J Am Soc Nephrol. 2025 Jun 1;36(6):1105-1115. doi: 10.1681/ASN.0000000602. Epub 2025 Jan 16. J Am Soc Nephrol. 2025. PMID: 39820177

10

Plasma Biomarkers of Kidney Health and Mortality in Diabetes and Chronic Kidney Disease in the REGARDS Study.

Chen TK, Estrella MM, Katz R, Sarnak MJ, Grams ME, Cushman M, Levitan EB, Parikh CR, Kimmel PL, Bonventre JV, Coca SG, Gutiérrez OM, Ix JH, Shlipak MG. Chen TK, et al. Clin J Am Soc Nephrol. 2024 Dec 1;19(12):1585-1593. doi: 10.2215/CJN.0000000000000544. Epub 2024 Sep 20. Clin J Am Soc Nephrol. 2024. PMID: 39652331 Free PMC article.

11

Dynamic Kidney Organoid Microphysiological Analysis Platform.

Hong S, Song M, Miyoshi T, Morizane R, Bonventre JV, Lee LP. Hong S, et al. bioRxiv [Preprint]. 2024 Oct 29:2024.10.27.620552. doi: 10.1101/2024.10.27.620552. bioRxiv. 2024. PMID: 39554191 Free PMC article. Preprint.

12

Sex Differences in Hypertension and Its Management Throughout Life.

Yeo WJ, Abraham R, Surapaneni AL, Schlosser P, Ballew SH, Ozkan B, Flaherty CM, Yu B, Bonventre JV, Parikh CR, Kimmel PL, Vasan RS, Coresh J, Grams ME. Yeo WJ, et al. Hypertension. 2024 Nov;81(11):2263-2274. doi: 10.1161/HYPERTENSIONAHA.124.22980. Epub 2024 Sep 4. Hypertension. 2024. PMID: 39229711 Free PMC article.

13

Urine Biomarkers of Kidney Tubule Health and Risk of Incident CKD in Persons Without Diabetes: The ARIC, MESA, and REGARDS Studies.

Amatruda JG, Katz R, Rebholz CM, Sarnak MJ, Gutierrez OM, Schrauben SJ, Greenberg JH, Coresh J, Cushman M, Waikar S, Parikh CR, Schelling JR, Jogalekar MP, Bonventre JV, Vasan RS, Kimmel PL, Ix JH, Shlipak MG; CKD Biomarkers Consortium. Amatruda JG, et al. Kidney Med. 2024 Apr 26;6(6):100834. doi: 10.1016/j.xkme.2024.100834. eCollection 2024 Jun. Kidney Med. 2024. PMID: 38826568 Free PMC article.

14

Intestinal CXCR6⁺ ILC3s migrate to the kidney and exacerbate renal fibrosis via IL-23 receptor signaling enhanced by PD-1 expression.

Liang Z, Tang Z, Zhu C, Li F, Chen S, Han X, Zheng R, Hu X, Lin R, Pei Q, Yin C, Wang J, Tang C, Cao N, Zhao J, Wang R, Li X, Luo N, Wen Q, Yu J, Li J, Xia X, Zheng X, Wang X, Huang N, Zhong Z, Mo C, Chen P, Wang Y, Fan J, Guo Y, Zhong H, Liu J, Peng Z, Mao H, Shi GP, Bonventre JV, Chen W, Zhou Y. Liang Z, et al. Immunity. 2024 Jun 11;57(6):1306-1323.e8. doi: 10.1016/j.immuni.2024.05.004. Epub 2024 May 29. Immunity. 2024. PMID: 38815582 Free PMC article.

15

Plasma Kidney Injury Molecule-1 for Preoperative Prediction of Renal Cell Carcinoma Versus Benign Renal Masses, and Association With Clinical Outcomes.

Xu W, Gaborieau V, Niman SM, Mukeria A, Liu X, Maremanda KP, Takakura A, Zaridze D, Freedman ML, Xie W, McDermott DF, Choueiri TK, Catalano PJ, Sabbisetti V, Bonventre JV, Pierorazio PM, Singla N, Brennan P, Bhatt RS. Xu W, et al. J Clin Oncol. 2024 Aug 1;42(22):2691-2701. doi: 10.1200/JCO.23.00699. Epub 2024 May 3. J Clin Oncol. 2024. PMID: 38701382 Free PMC article.

16

Clinical Decision Support for Hypertension Management in Chronic Kidney Disease: A Randomized Clinical Trial.

Samal L, Kilgallon JL, Lipsitz S, Baer HJ, McCoy A, Gannon M, Noonan S, Dunk R, Chen SW, Chay WI, Fay R, Garabedian PM, Wu E, Wien M, Blecker S, Salmasian H, Bonventre JV, McMahon GM, Bates DW, Waikar SS, Linder JA, Wright A, Dykes P. Samal L, et al. JAMA Intern Med. 2024 May 1;184(5):484-492. doi: 10.1001/jamainternmed.2023.8315. JAMA Intern Med. 2024. PMID: 38466302 Free PMC article. Clinical Trial.

17

Energy depletion by cell proliferation sensitizes the kidney epithelial cells to injury.

Galichon P, Lannoy M, Li L, Serre J, Vandermeersch S, Legouis D, Valerius MT, Hadchouel J, Bonventre JV. Galichon P, et al. Am J Physiol Renal Physiol. 2024 Mar 1;326(3):F326-F337. doi: 10.1152/ajprenal.00023.2023. Epub 2024 Jan 11. Am J Physiol Renal Physiol. 2024. PMID: 38205542 Free PMC article.

18

3D Hydrogel Encapsulation Regulates Nephrogenesis in Kidney Organoids.

Nerger BA, Sinha S, Lee NN, Cheriyan M, Bertsch P, Johnson CP, Mahadevan L, Bonventre JV, Mooney DJ. Nerger BA, et al. Adv Mater. 2024 Apr;36(14):e2308325. doi: 10.1002/adma.202308325. Epub 2024 Jan 10. Adv Mater. 2024. PMID: 38180232 Free PMC article.

19

Circulating Metabolomic Associations with Neurocognitive Outcomes in Pediatric CKD.

Lee AM, Xu Y, Hooper SR, Abraham AG, Hu J, Xiao R, Matheson MB, Brunson C, Rhee EP, Coresh J, Vasan RS, Schrauben S, Kimmel PL, Warady BA, Furth SL, Hartung EA, Denburg MR; CKD Biomarkers Consortium. Lee AM, et al. Clin J Am Soc Nephrol. 2024 Jan 1;19(1):13-25. doi: 10.2215/CJN.0000000000000318. Epub 2023 Oct 23. Clin J Am Soc Nephrol. 2024. PMID: 37871960 Free PMC article.

20

Plasma Biomarkers and Incident CKD Among Individuals Without Diabetes.

Le D, Chen J, Shlipak MG, Ix JH, Sarnak MJ, Gutierrez OM, Schelling JR, Bonventre JV, Sabbisetti VS, Schrauben SJ, Coca SG, Kimmel PL, Vasan RS, Grams ME, Parikh C, Coresh J, Rebholz CM; Chronic Kidney Disease Biomarkers Consortium. Le D, et al. Kidney Med. 2023 Aug 25;5(11):100719. doi: 10.1016/j.xkme.2023.100719. eCollection 2023 Nov. Kidney Med. 2023. PMID: 37841418 Free PMC article.

21

Urinary Biomarkers and Kidney Injury in VA NEPHRON-D: Phenotyping Acute Kidney Injury in Clinical Trials.

Kiernan EA, Hu D, Philbrook HT, Ix JH, Bonventre JV, Coca SG, Moledina DG, Fried LF, Shlipak MG, Parikh CR. Kiernan EA, et al. Am J Kidney Dis. 2024 Feb;83(2):151-161. doi: 10.1053/j.ajkd.2023.07.012. Epub 2023 Sep 17. Am J Kidney Dis. 2024. PMID: 37726051 Free PMC article.

22

Immune-infiltrated kidney organoid-on-chip model for assessing T cell bispecific antibodies.

Kroll KT, Mata MM, Homan KA, Micallef V, Carpy A, Hiratsuka K, Morizane R, Moisan A, Gubler M, Walz AC, Marrer-Berger E, Lewis JA. Kroll KT, et al. Proc Natl Acad Sci U S A. 2023 Aug 29;120(35):e2305322120. doi: 10.1073/pnas.2305322120. Epub 2023 Aug 21. Proc Natl Acad Sci U S A. 2023. PMID: 37603766 Free PMC article.

23

Urinary Biomarkers of Kidney Tubule Health and Mortality in Persons with CKD and Diabetes Mellitus.

Vasquez-Rios G, Katz R, Levitan EB, Cushman M, Parikh CR, Kimmel PL, Bonventre JV, Waikar SS, Schrauben SJ, Greenberg JH, Sarnak MJ, Ix JH, Shlipak MG, Gutierrez OM. Vasquez-Rios G, et al. Kidney360. 2023 Sep 1;4(9):e1257-e1264. doi: 10.34067/KID.0000000000000226. Epub 2023 Aug 3. Kidney360. 2023. PMID: 37533144 Free PMC article.

24

Directed differentiation of ureteric bud and collecting duct organoids from human pluripotent stem cells.

Shi M, Fu P, Bonventre JV, McCracken KW. Shi M, et al. Nat Protoc. 2023 Aug;18(8):2485-2508. doi: 10.1038/s41596-023-00847-2. Epub 2023 Jul 17. Nat Protoc. 2023. PMID: 37460630 Free PMC article. Review.

25

Mast cells link immune sensing to antigen-avoidance behaviour.

Plum T, Binzberger R, Thiele R, Shang F, Postrach D, Fung C, Fortea M, Stakenborg N, Wang Z, Tappe-Theodor A, Poth T, MacLaren DAA, Boeckxstaens G, Kuner R, Pitzer C, Monyer H, Xin C, Bonventre JV, Tanaka S, Voehringer D, Vanden Berghe P, Strid J, Feyerabend TB, Rodewald HR. Plum T, et al. Nature. 2023 Aug;620(7974):634-642. doi: 10.1038/s41586-023-06188-0. Epub 2023 Jul 12. Nature. 2023. PMID: 37438525 Free PMC article.

26

Associations of Biomarkers of Kidney Tubule Health, Injury, and Inflammation with Left Ventricular Hypertrophy in Children with CKD.

Jiang K, Greenberg JH, Abraham A, Xu Y, Schelling JR, Feldman HI, Schrauben SJ, Waikar SS, Shlipak MG, Wettersten N, Coca SG, Vasan RS, Gutierrez OM, Ix JH, Warady BA, Kimmel PL, Bonventre JV, Parikh CR, Mitsnefes MM, Denburg MR, Furth S; CKD Biomarkers Consortium. Jiang K, et al. Kidney360. 2023 Aug 1;4(8):1039-1047. doi: 10.34067/KID.0000000000000183. Epub 2023 Jun 12. Kidney360. 2023. PMID: 37303083 Free PMC article.

27

Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis.

O'Sullivan ED, Mylonas KJ, Xin C, Baird DP, Carvalho C, Docherty MH, Campbell R, Matchett KP, Waddell SH, Walker AD, Gallagher KM, Jia S, Leung S, Laird A, Wilflingseder J, Willi M, Reck M, Finnie S, Pisco A, Gordon-Keylock S, Medvinsky A, Boulter L, Henderson NC, Kirschner K, Chandra T, Conway BR, Hughes J, Denby L, Bonventre JV, Ferenbach DA. O'Sullivan ED, et al. Sci Transl Med. 2023 May 31;15(698):eabn0736. doi: 10.1126/scitranslmed.abn0736. Epub 2023 May 31. Sci Transl Med. 2023. PMID: 37256934 Free PMC article.

28

Association of Kidney Tubule Biomarkers With Cardiac Structure and Function in the Multiethnic Study of Atherosclerosis.

Wettersten N, Katz R, Greenberg JH, Gutierrez OM, Lima JAC, Sarnak MJ, Schrauben S, Deo R, Bonventre J, Vasan RS, Kimmel PL, Shlipak M, Ix JH. Wettersten N, et al. Am J Cardiol. 2023 Jun 1;196:11-18. doi: 10.1016/j.amjcard.2023.02.031. Epub 2023 Apr 21. Am J Cardiol. 2023. PMID: 37086700 Free PMC article.

29

Urinary KIM-1 is not correlated with gestational age among 5-year-old children born prematurely.

Restrepo JM, Torres-Canchala L, Bonventre JV, Arias JC, Ferguson M, Villegas A, Ramirez O, Filler G. Restrepo JM, et al. Front Pediatr. 2023 Mar 20;11:1038206. doi: 10.3389/fped.2023.1038206. eCollection 2023. Front Pediatr. 2023. PMID: 37020658 Free PMC article.

30

ATP/ADP biosensor organoids for drug nephrotoxicity assessment.

Susa K, Kobayashi K, Galichon P, Matsumoto T, Tamura A, Hiratsuka K, Gupta NR, Yazdi IK, Bonventre JV, Morizane R. Susa K, et al. Front Cell Dev Biol. 2023 Mar 2;11:1138504. doi: 10.3389/fcell.2023.1138504. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 36936695 Free PMC article.

31

Urinary Biomarkers of Tubular Health and Risk for Kidney Function Decline or Mortality in Diabetes.

Chen TK, Coca SG, Thiessen-Philbrook HR, Heerspink HJL, Obeid W, Ix JH, Fried LF, Bonventre JV, El-Khoury JM, Shlipak MG, Parikh CR; CKD Biomarkers Consortium (BioCon). Chen TK, et al. Am J Nephrol. 2022;53(11-12):775-785. doi: 10.1159/000528918. Epub 2023 Jan 11. Am J Nephrol. 2022. PMID: 36630924 Free PMC article.

32

Machine Learning for Acute Kidney Injury Prediction in the Intensive Care Unit.

Gottlieb ER, Samuel M, Bonventre JV, Celi LA, Mattie H. Gottlieb ER, et al. Adv Chronic Kidney Dis. 2022 Sep;29(5):431-438. doi: 10.1053/j.ackd.2022.06.005. Adv Chronic Kidney Dis. 2022. PMID: 36253026 Free PMC article. Review.

33

Human ureteric bud organoids recapitulate branching morphogenesis and differentiate into functional collecting duct cell types.

Shi M, McCracken KW, Patel AB, Zhang W, Ester L, Valerius MT, Bonventre JV. Shi M, et al. Nat Biotechnol. 2023 Feb;41(2):252-261. doi: 10.1038/s41587-022-01429-5. Epub 2022 Aug 29. Nat Biotechnol. 2023. PMID: 36038632 Free PMC article.

34

Acute Kidney Injury Associates with Long-Term Increases in Plasma TNFR1, TNFR2, and KIM-1: Findings from the CRIC Study.

McCoy IE, Hsu JY, Bonventre JV, Parikh CR, Go AS, Liu KD, Ricardo AC, Srivastava A, Cohen DL, He J, Chen J, Rao PS, Hsu CY; Chronic Renal Insufficiency Cohort (CRIC) Study Investigators. McCoy IE, et al. J Am Soc Nephrol. 2022 Jun;33(6):1173-1181. doi: 10.1681/ASN.2021111453. Epub 2022 Mar 16. J Am Soc Nephrol. 2022. PMID: 35296554 Free PMC article.

35

Biomimetic models of the glomerulus.

Valverde MG, Mille LS, Figler KP, Cervantes E, Li VY, Bonventre JV, Masereeuw R, Zhang YS. Valverde MG, et al. Nat Rev Nephrol. 2022 Apr;18(4):241-257. doi: 10.1038/s41581-021-00528-x. Epub 2022 Jan 21. Nat Rev Nephrol. 2022. PMID: 35064233 Free PMC article. Review.

36

From Bench to the Clinic: The Path to Translation of Nanotechnology-Enabled mRNA SARS-CoV-2 Vaccines.

Lopez-Cantu DO, Wang X, Carrasco-Magallanes H, Afewerki S, Zhang X, Bonventre JV, Ruiz-Esparza GU. Lopez-Cantu DO, et al. Nanomicro Lett. 2022 Jan 3;14(1):41. doi: 10.1007/s40820-021-00771-8. Nanomicro Lett. 2022. PMID: 34981278 Free PMC article. Review.

37

SGLT2 Inhibitors and the Risk of Acute Kidney Injury in Older Adults With Type 2 Diabetes.

Zhuo M, Paik JM, Wexler DJ, Bonventre JV, Kim SC, Patorno E. Zhuo M, et al. Am J Kidney Dis. 2022 Jun;79(6):858-867.e1. doi: 10.1053/j.ajkd.2021.09.015. Epub 2021 Nov 8. Am J Kidney Dis. 2022. PMID: 34762974 Free PMC article.

38

Associations of Plasma Biomarkers of Inflammation, Fibrosis, and Kidney Tubular Injury With Progression of Diabetic Kidney Disease: A Cohort Study.

Gutiérrez OM, Shlipak MG, Katz R, Waikar SS, Greenberg JH, Schrauben SJ, Coca S, Parikh CR, Vasan RS, Feldman HI, Kimmel PL, Cushman M, Bonventre JV, Sarnak MJ, Ix JH. Gutiérrez OM, et al. Am J Kidney Dis. 2022 Jun;79(6):849-857.e1. doi: 10.1053/j.ajkd.2021.09.018. Epub 2021 Nov 6. Am J Kidney Dis. 2022. PMID: 34752914 Free PMC article.

39

Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease.

Xin C, Lei J, Wang Q, Yin Y, Yang X, Moran Guerrero JA, Sabbisetti V, Sun X, Vaidya VS, Bonventre JV. Xin C, et al. iScience. 2021 Sep 29;24(10):103193. doi: 10.1016/j.isci.2021.103193. eCollection 2021 Oct 22. iScience. 2021. PMID: 34703992 Free PMC article.

40

2-Methoxyestradiol Ameliorates Angiotensin II-Induced Hypertension by Inhibiting Cytosolic Phospholipase A₂α Activity in Female Mice.

Song CY, Singh P, Motiwala M, Shin JS, Lew J, Dutta SR, Gonzalez FJ, Bonventre JV, Malik KU. Song CY, et al. Hypertension. 2021 Nov;78(5):1368-1381. doi: 10.1161/HYPERTENSIONAHA.121.18181. Epub 2021 Oct 11. Hypertension. 2021. PMID: 34628937 Free PMC article.

41

Urine Biomarkers of Kidney Tubule Health, Injury, and Inflammation are Associated with Progression of CKD in Children.

Greenberg JH, Abraham AG, Xu Y, Schelling JR, Feldman HI, Sabbisetti VS, Ix JH, Jogalekar MP, Coca S, Waikar SS, Shlipak MG, Warady BA, Vasan RS, Kimmel PL, Bonventre JV, Denburg M, Parikh CR, Furth S; CKD Biomarkers Consortium; CKD Biomarker consortium. Greenberg JH, et al. J Am Soc Nephrol. 2021 Oct;32(10):2664-2677. doi: 10.1681/ASN.2021010094. Epub 2021 Sep 20. J Am Soc Nephrol. 2021. PMID: 34544821 Free PMC article.

42

6β-Hydroxytestosterone Promotes Angiotensin II-Induced Hypertension via Enhanced Cytosolic Phospholipase A₂α Activity.

Singh P, Song CY, Dutta SR, Pingili A, Shin JS, Gonzalez FJ, Bonventre JV, Malik KU. Singh P, et al. Hypertension. 2021 Sep;78(4):1053-1066. doi: 10.1161/HYPERTENSIONAHA.121.17927. Epub 2021 Aug 23. Hypertension. 2021. PMID: 34420370 Free PMC article.

43

Comparison of proteomic methods in evaluating biomarker-AKI associations in cardiac surgery patients.

Liu RX, Thiessen-Philbrook HR, Vasan RS, Coresh J, Ganz P, Bonventre JV, Kimmel PL, Parikh CR. Liu RX, et al. Transl Res. 2021 Dec;238:49-62. doi: 10.1016/j.trsl.2021.07.005. Epub 2021 Jul 31. Transl Res. 2021. PMID: 34343625 Free PMC article.

44

Molecularly Imprinted Polymer Nanogels for Protein Recognition: Direct Proof of Specific Binding Sites by Solution STD and WaterLOGSY NMR Spectroscopies.

Mier A, Maffucci I, Merlier F, Prost E, Montagna V, Ruiz-Esparza GU, Bonventre JV, Dhal PK, Tse Sum Bui B, Sakhaii P, Haupt K. Mier A, et al. Angew Chem Int Ed Engl. 2021 Sep 13;60(38):20849-20857. doi: 10.1002/anie.202106507. Epub 2021 Aug 24. Angew Chem Int Ed Engl. 2021. PMID: 34296498 Free PMC article.

45

Association of Coding Variants in Hydroxysteroid 17-beta Dehydrogenase 14 (HSD17B14) with Reduced Progression to End Stage Kidney Disease in Type 1 Diabetes.

Mychaleckyj JC, Valo E, Ichimura T, Ahluwalia TS, Dina C, Miller RG, Shabalin IG, Gyorgy B, Cao J, Onengut-Gumuscu S, Satake E, Smiles AM, Haukka JK, Tregouet DA, Costacou T, O'Neil K, Paterson AD, Forsblom C, Keenan HA, Pezzolesi MG, Pragnell M, Galecki A, Rich SS, Sandholm N, Klein R, Klein BE, Susztak K, Orchard TJ, Korstanje R, King GL, Hadjadj S, Rossing P, Bonventre JV, Groop PH, Warram JH, Krolewski AS. Mychaleckyj JC, et al. J Am Soc Nephrol. 2021 Oct;32(10):2634-2651. doi: 10.1681/ASN.2020101457. Epub 2021 Jul 14. J Am Soc Nephrol. 2021. PMID: 34261756 Free PMC article.

46

Plasma Kidney Injury Molecule 1 in CKD: Findings From the Boston Kidney Biopsy Cohort and CRIC Studies.

Schmidt IM, Srivastava A, Sabbisetti V, McMahon GM, He J, Chen J, Kusek JW, Taliercio J, Ricardo AC, Hsu CY, Kimmel PL, Liu KD, Mifflin TE, Nelson RG, Vasan RS, Xie D, Zhang X, Palsson R, Stillman IE, Rennke HG, Feldman HI, Bonventre JV, Waikar SS; Chronic Kidney Disease Biomarkers Consortium and the CRIC Study Investigators. Schmidt IM, et al. Am J Kidney Dis. 2022 Feb;79(2):231-243.e1. doi: 10.1053/j.ajkd.2021.05.013. Epub 2021 Jun 25. Am J Kidney Dis. 2022. PMID: 34175376 Free PMC article.

47

Nephrotoxicity Assessment with Human Kidney Tubuloids using Spherical Nucleic Acid-Based mRNA Nanoflares.

Wiraja C, Mori Y, Ichimura T, Hwang J, Xu C, Bonventre JV. Wiraja C, et al. Nano Lett. 2021 Jul 14;21(13):5850-5858. doi: 10.1021/acs.nanolett.1c01840. Epub 2021 Jun 22. Nano Lett. 2021. PMID: 34156251 Free PMC article.

48

Orphan nuclear receptor COUP-TFII enhances myofibroblast glycolysis leading to kidney fibrosis.

Li L, Galichon P, Xiao X, Figueroa-Ramirez AC, Tamayo D, Lee JJ, Kalocsay M, Gonzalez-Sanchez D, Chancay MS, McCracken KW, Lee NN, Ichimura T, Mori Y, Valerius MT, Wilflingseder J, Lemos DR, Edelman ER, Bonventre JV. Li L, et al. EMBO Rep. 2021 Jun 4;22(6):e51169. doi: 10.15252/embr.202051169. Epub 2021 May 25. EMBO Rep. 2021. PMID: 34031962 Free PMC article.

49

KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease.

Mori Y, Ajay AK, Chang JH, Mou S, Zhao H, Kishi S, Li J, Brooks CR, Xiao S, Woo HM, Sabbisetti VS, Palmer SC, Galichon P, Li L, Henderson JM, Kuchroo VK, Hawkins J, Ichimura T, Bonventre JV. Mori Y, et al. Cell Metab. 2021 May 4;33(5):1042-1061.e7. doi: 10.1016/j.cmet.2021.04.004. Cell Metab. 2021. PMID: 33951465 Free PMC article.

50

Editorial Expression of Concern: Water and sodium in heart failure: a spotlight on congestion.

Parrinello G, Greene SJ, Torres D, Alderman M, Bonventre JV, Pasquale PD, Gargani L, Nohria A, Fonarow GC, Vaduganathan M, Butler J, Paterna S, Stevenson LW, Gheorghiade M. Parrinello G, et al. Heart Fail Rev. 2021 Nov;26(6):1529. doi: 10.1007/s10741-021-10113-w. Heart Fail Rev. 2021. PMID: 33913077 No abstract available.

51

The Associations of Plasma Biomarkers of Inflammation With Histopathologic Lesions, Kidney Disease Progression, and Mortality-The Boston Kidney Biopsy Cohort Study.

Srivastava A, Schmidt IM, Palsson R, Weins A, Bonventre JV, Sabbisetti V, Stillman IE, Rennke HG, Waikar SS. Srivastava A, et al. Kidney Int Rep. 2021 Jan 6;6(3):685-694. doi: 10.1016/j.ekir.2020.12.025. eCollection 2021 Mar. Kidney Int Rep. 2021. PMID: 33732983 Free PMC article.

52

KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and Kidney.

Mori Y, Fink C, Ichimura T, Sako K, Mori M, Lee NN, Aschauer P, Padmanabha Das KM, Hong S, Song M, Padera RF, Weins A, Lee LP, Nasr ML, Dekaban GA, Dikeakos JD, Bonventre JV. Mori Y, et al. medRxiv [Preprint]. 2022 Jan 11:2020.09.16.20190694. doi: 10.1101/2020.09.16.20190694. medRxiv. 2022. PMID: 32995803 Free PMC article. Preprint.

53

Reply.

Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De La Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. Yonker LM, et al. J Pediatr. 2021 Jan;228:317-319. doi: 10.1016/j.jpeds.2020.09.049. Epub 2020 Sep 21. J Pediatr. 2021. PMID: 32971143 Free PMC article. No abstract available.

54

Reply.

Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De la Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. Yonker LM, et al. J Pediatr. 2021 Jan;228:320-323. doi: 10.1016/j.jpeds.2020.09.035. Epub 2020 Sep 18. J Pediatr. 2021. PMID: 32956696 Free PMC article. No abstract available.

55

Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Presentation, Infectivity, and Immune Responses.

Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De la Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. Yonker LM, et al. J Pediatr. 2020 Dec;227:45-52.e5. doi: 10.1016/j.jpeds.2020.08.037. Epub 2020 Aug 20. J Pediatr. 2020. PMID: 32827525 Free PMC article.

56

Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury.

Wilflingseder J, Willi M, Lee HK, Olauson H, Jankowski J, Ichimura T, Erben R, Valerius MT, Hennighausen L, Bonventre JV. Wilflingseder J, et al. Nat Commun. 2020 Jul 7;11(1):3383. doi: 10.1038/s41467-020-17205-5. Nat Commun. 2020. PMID: 32636391 Free PMC article.

57

Initial Validation of a Machine Learning-Derived Prognostic Test (KidneyIntelX) Integrating Biomarkers and Electronic Health Record Data To Predict Longitudinal Kidney Outcomes.

Chauhan K, Nadkarni GN, Fleming F, McCullough J, He CJ, Quackenbush J, Murphy B, Donovan MJ, Coca SG, Bonventre JV. Chauhan K, et al. Kidney360. 2020 Jun 30;1(8):731-739. doi: 10.34067/KID.0002252020. eCollection 2020 Aug 27. Kidney360. 2020. PMID: 35372952 Free PMC article.

58

Plasma Biomarkers of Tubular Injury and Inflammation Are Associated with CKD Progression in Children.

Greenberg JH, Abraham AG, Xu Y, Schelling JR, Feldman HI, Sabbisetti VS, Gonzalez MC, Coca S, Schrauben SJ, Waikar SS, Ramachandran VS, Shlipak MG, Warady B, Kimmel PL, Bonventre JV, Denburg M, Parikh CR, Furth S; CKD Biomarkers Consortium. Greenberg JH, et al. J Am Soc Nephrol. 2020 May;31(5):1067-1077. doi: 10.1681/ASN.2019070723. Epub 2020 Mar 31. J Am Soc Nephrol. 2020. PMID: 32234829 Free PMC article.

59

A single combination gene therapy treats multiple age-related diseases.

Davidsohn N, Pezone M, Vernet A, Graveline A, Oliver D, Slomovic S, Punthambaker S, Sun X, Liao R, Bonventre JV, Church GM. Davidsohn N, et al. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23505-23511. doi: 10.1073/pnas.1910073116. Epub 2019 Nov 4. Proc Natl Acad Sci U S A. 2019. PMID: 31685628 Free PMC article.

60

Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses.

Kishi S, Brooks CR, Taguchi K, Ichimura T, Mori Y, Akinfolarin A, Gupta N, Galichon P, Elias BC, Suzuki T, Wang Q, Gewin L, Morizane R, Bonventre JV. Kishi S, et al. J Clin Invest. 2019 Nov 1;129(11):4797-4816. doi: 10.1172/JCI122313. J Clin Invest. 2019. PMID: 31589169 Free PMC article.

61

A Technology Roadmap for Innovative Approaches to Kidney Replacement Therapies: A Catalyst for Change.

Bonventre JV, Hurst FP, West M, Wu I, Roy-Chaudhury P, Sheldon M. Bonventre JV, et al. Clin J Am Soc Nephrol. 2019 Oct 7;14(10):1539-1547. doi: 10.2215/CJN.02570319. Epub 2019 Sep 27. Clin J Am Soc Nephrol. 2019. PMID: 31562182 Free PMC article.

62

Differential Roles of Cysteinyl Cathepsins in TGF-β Signaling and Tissue Fibrosis.

Zhang X, Zhou Y, Yu X, Huang Q, Fang W, Li J, Bonventre JV, Sukhova GK, Libby P, Shi GP. Zhang X, et al. iScience. 2019 Sep 27;19:607-622. doi: 10.1016/j.isci.2019.08.014. Epub 2019 Aug 9. iScience. 2019. PMID: 31446224 Free PMC article.

63

Summary of the International Conference on Onco-Nephrology: an emerging field in medicine.

Capasso A, Benigni A, Capitanio U, Danesh FR, Di Marzo V, Gesualdo L, Grandaliano G, Jaimes EA, Malyszko J, Perazella MA, Qian Q, Ronco P, Rosner MH, Trepiccione F, Viggiano D, Zoccali C, Capasso G; International Conference on Onco-Nephrology Participants. Capasso A, et al. Kidney Int. 2019 Sep;96(3):555-567. doi: 10.1016/j.kint.2019.04.043. Epub 2019 May 31. Kidney Int. 2019. PMID: 31445584 Free article.

64

Renal Effects of Intensive Volume Removal in Heart Failure Patients With Preexisting Worsening Renal Function.

Rao VS, Ahmad T, Brisco-Bacik MA, Bonventre JV, Wilson FP, Siew ED, Felker GM, Anstrom KK, Mahoney DD, Bart BA, Tang WHW, Velazquez EJ, Testani JM. Rao VS, et al. Circ Heart Fail. 2019 Jun;12(6):e005552. doi: 10.1161/CIRCHEARTFAILURE.118.005552. Epub 2019 Jun 5. Circ Heart Fail. 2019. PMID: 31163974 Free PMC article.

65

Cellular Senescence in the Kidney.

Docherty MH, O'Sullivan ED, Bonventre JV, Ferenbach DA. Docherty MH, et al. J Am Soc Nephrol. 2019 May;30(5):726-736. doi: 10.1681/ASN.2018121251. Epub 2019 Apr 18. J Am Soc Nephrol. 2019. PMID: 31000567 Free PMC article. Review.

66

Recent advances in acute kidney injury and its consequences and impact on chronic kidney disease.

Zuk A, Bonventre JV. Zuk A, et al. Curr Opin Nephrol Hypertens. 2019 Jul;28(4):397-405. doi: 10.1097/MNH.0000000000000504. Curr Opin Nephrol Hypertens. 2019. PMID: 30925515 Free PMC article. Review.

67

Flow-enhanced vascularization and maturation of kidney organoids in vitro.

Homan KA, Gupta N, Kroll KT, Kolesky DB, Skylar-Scott M, Miyoshi T, Mau D, Valerius MT, Ferrante T, Bonventre JV, Lewis JA, Morizane R. Homan KA, et al. Nat Methods. 2019 Mar;16(3):255-262. doi: 10.1038/s41592-019-0325-y. Epub 2019 Feb 11. Nat Methods. 2019. PMID: 30742039 Free PMC article.

68

Cyclin G1 and TASCC regulate kidney epithelial cell G₂-M arrest and fibrotic maladaptive repair.

Canaud G, Brooks CR, Kishi S, Taguchi K, Nishimura K, Magassa S, Scott A, Hsiao LL, Ichimura T, Terzi F, Yang L, Bonventre JV. Canaud G, et al. Sci Transl Med. 2019 Jan 23;11(476):eaav4754. doi: 10.1126/scitranslmed.aav4754. Sci Transl Med. 2019. PMID: 30674655 Free PMC article.

69

cPLA2α-/- sympathetic neurons exhibit increased membrane excitability and loss of N-Type Ca2+ current inhibition by M1 muscarinic receptor signaling.

Liu L, Bonventre JV, Rittenhouse AR. Liu L, et al. PLoS One. 2018 Dec 17;13(12):e0201322. doi: 10.1371/journal.pone.0201322. eCollection 2018. PLoS One. 2018. PMID: 30557348 Free PMC article.

70

Abemaciclib Inhibits Renal Tubular Secretion Without Changing Glomerular Filtration Rate.

Chappell JC, Turner PK, Pak YA, Bacon J, Chiang AY, Royalty J, Hall SD, Kulanthaivel P, Bonventre JV. Chappell JC, et al. Clin Pharmacol Ther. 2019 May;105(5):1187-1195. doi: 10.1002/cpt.1296. Epub 2018 Dec 30. Clin Pharmacol Ther. 2019. PMID: 30449032 Free PMC article.

71

Prediction of DNA Repair Inhibitor Response in Short-Term Patient-Derived Ovarian Cancer Organoids.

Hill SJ, Decker B, Roberts EA, Horowitz NS, Muto MG, Worley MJ Jr, Feltmate CM, Nucci MR, Swisher EM, Nguyen H, Yang C, Morizane R, Kochupurakkal BS, Do KT, Konstantinopoulos PA, Liu JF, Bonventre JV, Matulonis UA, Shapiro GI, Berkowitz RS, Crum CP, D'Andrea AD. Hill SJ, et al. Cancer Discov. 2018 Nov;8(11):1404-1421. doi: 10.1158/2159-8290.CD-18-0474. Epub 2018 Sep 13. Cancer Discov. 2018. PMID: 30213835 Free PMC article.

72

Effect of Combined Gluten-Free, Dairy-Free Diet in Children With Steroid-Resistant Nephrotic Syndrome: An Open Pilot Trial.

Leon J, Pérez-Sáez MJ, Uffing A, Murakami N, Watanabe A, Cureton P, Kenyon V, Keating L, Yee K, Fernandes Satiro CA, Yu B, Bonventre JV, Fasano A, Riella LV. Leon J, et al. Kidney Int Rep. 2018 Mar 3;3(4):851-860. doi: 10.1016/j.ekir.2018.02.011. eCollection 2018 Jul. Kidney Int Rep. 2018. PMID: 30116795 Free PMC article.

73

Kidney injury molecule-1 identifies antemortem injury in postmortem adult and fetal kidney.

Yin W, Zhang PL, Macknis JK, Lin F, Bonventre JV. Yin W, et al. Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1637-F1643. doi: 10.1152/ajprenal.00060.2018. Epub 2018 Aug 15. Am J Physiol Renal Physiol. 2018. PMID: 30110569 Free PMC article.

74

CRISPR/Cas9-based Targeted Genome Editing for the Development of Monogenic Diseases Models with Human Pluripotent Stem Cells.

Gupta N, Susa K, Yoda Y, Bonventre JV, Valerius MT, Morizane R. Gupta N, et al. Curr Protoc Stem Cell Biol. 2018 May;45(1):e50. doi: 10.1002/cpsc.50. Epub 2018 Apr 26. Curr Protoc Stem Cell Biol. 2018. PMID: 30040245 Free PMC article.

75

KIM-1 as a Blood-Based Marker for Early Detection of Kidney Cancer: A Prospective Nested Case-Control Study.

Scelo G, Muller DC, Riboli E, Johansson M, Cross AJ, Vineis P, Tsilidis KK, Brennan P, Boeing H, Peeters PHM, Vermeulen RCH, Overvad K, Bueno-de-Mesquita HB, Severi G, Perduca V, Kvaskoff M, Trichopoulou A, La Vecchia C, Karakatsani A, Palli D, Sieri S, Panico S, Weiderpass E, Sandanger TM, Nøst TH, Agudo A, Quirós JR, Rodríguez-Barranco M, Chirlaque MD, Key TJ, Khanna P, Bonventre JV, Sabbisetti VS, Bhatt RS. Scelo G, et al. Clin Cancer Res. 2018 Nov 15;24(22):5594-5601. doi: 10.1158/1078-0432.CCR-18-1496. Epub 2018 Jul 23. Clin Cancer Res. 2018. PMID: 30037816 Free PMC article.

76

Biological Variability of Estimated GFR and Albuminuria in CKD.

Waikar SS, Rebholz CM, Zheng Z, Hurwitz S, Hsu CY, Feldman HI, Xie D, Liu KD, Mifflin TE, Eckfeldt JH, Kimmel PL, Vasan RS, Bonventre JV, Inker LA, Coresh J; Chronic Kidney Disease Biomarkers Consortium Investigators. Waikar SS, et al. Am J Kidney Dis. 2018 Oct;72(4):538-546. doi: 10.1053/j.ajkd.2018.04.023. Epub 2018 Jul 18. Am J Kidney Dis. 2018. PMID: 30031564 Free PMC article.

77

Nitric Oxide Decreases Acute Kidney Injury and Stage 3 Chronic Kidney Disease after Cardiac Surgery.

Lei C, Berra L, Rezoagli E, Yu B, Dong H, Yu S, Hou L, Chen M, Chen W, Wang H, Zheng Q, Shen J, Jin Z, Chen T, Zhao R, Christie E, Sabbisetti VS, Nordio F, Bonventre JV, Xiong L, Zapol WM. Lei C, et al. Am J Respir Crit Care Med. 2018 Nov 15;198(10):1279-1287. doi: 10.1164/rccm.201710-2150OC. Am J Respir Crit Care Med. 2018. PMID: 29932345 Free PMC article.

78

Interleukin-1β Activates a MYC-Dependent Metabolic Switch in Kidney Stromal Cells Necessary for Progressive Tubulointerstitial Fibrosis.

Lemos DR, McMurdo M, Karaca G, Wilflingseder J, Leaf IA, Gupta N, Miyoshi T, Susa K, Johnson BG, Soliman K, Wang G, Morizane R, Bonventre JV, Duffield JS. Lemos DR, et al. J Am Soc Nephrol. 2018 Jun;29(6):1690-1705. doi: 10.1681/ASN.2017121283. Epub 2018 May 8. J Am Soc Nephrol. 2018. PMID: 29739813 Free PMC article.

79

Tctex-1, a novel interaction partner of Kidney Injury Molecule-1, is required for efferocytosis.

Ismail OZ, Sriranganathan S, Zhang X, Bonventre JV, Zervos AS, Gunaratnam L. Ismail OZ, et al. J Cell Physiol. 2018 Oct;233(10):6877-6895. doi: 10.1002/jcp.26578. Epub 2018 Apr 25. J Cell Physiol. 2018. PMID: 29693725 Free PMC article.

80

Acute Kidney Injury and Progression of Diabetic Kidney Disease.

Yu SM, Bonventre JV. Yu SM, et al. Adv Chronic Kidney Dis. 2018 Mar;25(2):166-180. doi: 10.1053/j.ackd.2017.12.005. Adv Chronic Kidney Dis. 2018. PMID: 29580581 Free PMC article. Review.

81

Overcoming Translational Barriers in Acute Kidney Injury: A Report from an NIDDK Workshop.

Zuk A, Palevsky PM, Fried L, Harrell FE Jr, Khan S, McKay DB, Devey L, Chawla L, de Caestecker M, Kaufman JS, Thompson BT, Agarwal A, Greene T, Okusa MD, Bonventre JV, Dember LM, Liu KD, Humphreys BD, Gossett D, Xie Y, Norton JM, Kimmel PL, Star RA. Zuk A, et al. Clin J Am Soc Nephrol. 2018 Jul 6;13(7):1113-1123. doi: 10.2215/CJN.06820617. Epub 2018 Mar 9. Clin J Am Soc Nephrol. 2018. PMID: 29523680 Free PMC article.

82

Markers of early progressive renal decline in type 2 diabetes suggest different implications for etiological studies and prognostic tests development.

Nowak N, Skupien J, Smiles AM, Yamanouchi M, Niewczas MA, Galecki AT, Duffin KL, Breyer MD, Pullen N, Bonventre JV, Krolewski AS. Nowak N, et al. Kidney Int. 2018 May;93(5):1198-1206. doi: 10.1016/j.kint.2017.11.024. Epub 2018 Feb 2. Kidney Int. 2018. PMID: 29398132 Free PMC article.

83

Worsening Renal Function in Patients With Acute Heart Failure Undergoing Aggressive Diuresis Is Not Associated With Tubular Injury.

Ahmad T, Jackson K, Rao VS, Tang WHW, Brisco-Bacik MA, Chen HH, Felker GM, Hernandez AF, O'Connor CM, Sabbisetti VS, Bonventre JV, Wilson FP, Coca SG, Testani JM. Ahmad T, et al. Circulation. 2018 May 8;137(19):2016-2028. doi: 10.1161/CIRCULATIONAHA.117.030112. Epub 2018 Jan 19. Circulation. 2018. PMID: 29352071 Free PMC article. Clinical Trial.

84

Brain Cytosolic Phospholipase A2α Mediates Angiotensin II-Induced Hypertension and Reactive Oxygen Species Production in Male Mice.

Song CY, Khan NS, Liao FF, Wang B, Shin JS, Bonventre JV, Malik KU. Song CY, et al. Am J Hypertens. 2018 Apr 13;31(5):622-629. doi: 10.1093/ajh/hpy009. Am J Hypertens. 2018. PMID: 29342227 Free PMC article.

85

Concise Review: Kidney Generation with Human Pluripotent Stem Cells.

Morizane R, Miyoshi T, Bonventre JV. Morizane R, et al. Stem Cells. 2017 Nov;35(11):2209-2217. doi: 10.1002/stem.2699. Epub 2017 Sep 26. Stem Cells. 2017. PMID: 28869686 Free PMC article. Review.

86

Cytosolic Phospholipase A₂α Promotes Pulmonary Inflammation and Systemic Disease during Streptococcus pneumoniae Infection.

Bhowmick R, Clark S, Bonventre JV, Leong JM, McCormick BA. Bhowmick R, et al. Infect Immun. 2017 Oct 18;85(11):e00280-17. doi: 10.1128/IAI.00280-17. Print 2017 Nov. Infect Immun. 2017. PMID: 28808157 Free PMC article.

87

Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end-stage renal disease.

Yamanouchi M, Skupien J, Niewczas MA, Smiles AM, Doria A, Stanton RC, Galecki AT, Duffin KL, Pullen N, Breyer MD, Bonventre JV, Warram JH, Krolewski AS. Yamanouchi M, et al. Kidney Int. 2017 Jul;92(1):258-266. doi: 10.1016/j.kint.2017.02.010. Epub 2017 Apr 7. Kidney Int. 2017. PMID: 28396115 Free PMC article.

88

Cisplatin-induced renal inflammation is ameliorated by cilastatin nephroprotection.

Humanes B, Camaño S, Lara JM, Sabbisetti V, González-Nicolás MÁ, Bonventre JV, Tejedor A, Lázaro A. Humanes B, et al. Nephrol Dial Transplant. 2017 Oct 1;32(10):1645-1655. doi: 10.1093/ndt/gfx005. Nephrol Dial Transplant. 2017. PMID: 28340076 Free PMC article.

89

Acute kidney injury: a problem of definition.

Barasch J, Zager R, Bonventre JV. Barasch J, et al. Lancet. 2017 Feb 25;389(10071):779-781. doi: 10.1016/S0140-6736(17)30543-3. Lancet. 2017. PMID: 28248160 Free PMC article. No abstract available.

90

CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice.

Zhou Y, Chen H, Liu L, Yu X, Sukhova GK, Yang M, Zhang L, Kyttaris VC, Tsokos GC, Stillman IE, Ichimura T, Bonventre JV, Libby P, Shi GP. Zhou Y, et al. J Immunol. 2017 Apr 1;198(7):2568-2577. doi: 10.4049/jimmunol.1600028. Epub 2017 Feb 20. J Immunol. 2017. PMID: 28219888 Free PMC article.

91

Kidney Organoids: A Translational Journey.

Morizane R, Bonventre JV. Morizane R, et al. Trends Mol Med. 2017 Mar;23(3):246-263. doi: 10.1016/j.molmed.2017.01.001. Epub 2017 Feb 7. Trends Mol Med. 2017. PMID: 28188103 Free PMC article. Review.

92

Biomarker validation with an imperfect reference: Issues and bounds.

Emerson SC, Waikar SS, Fuentes C, Bonventre JV, Betensky RA. Emerson SC, et al. Stat Methods Med Res. 2018 Oct;27(10):2933-2945. doi: 10.1177/0962280216689806. Epub 2017 Feb 6. Stat Methods Med Res. 2018. PMID: 28166709 Free PMC article.

93

The intensive care medicine agenda on acute kidney injury.

Pickkers P, Ostermann M, Joannidis M, Zarbock A, Hoste E, Bellomo R, Prowle J, Darmon M, Bonventre JV, Forni L, Bagshaw SM, Schetz M. Pickkers P, et al. Intensive Care Med. 2017 Sep;43(9):1198-1209. doi: 10.1007/s00134-017-4687-2. Epub 2017 Jan 30. Intensive Care Med. 2017. PMID: 28138736 Free PMC article. Review.

94

Repair after nephron ablation reveals limitations of neonatal neonephrogenesis.

Tögel F, Valerius MT, Freedman BS, Iatrino R, Grinstein M, Bonventre JV. Tögel F, et al. JCI Insight. 2017 Jan 26;2(2):e88848. doi: 10.1172/jci.insight.88848. JCI Insight. 2017. PMID: 28138555 Free PMC article.

95

A Role for 3D Printing in Kidney-on-a-Chip Platforms.

Sochol RD, Gupta NR, Bonventre JV. Sochol RD, et al. Curr Transplant Rep. 2016 Mar;3(1):82-92. doi: 10.1007/s40472-016-0085-x. Epub 2016 Jan 20. Curr Transplant Rep. 2016. PMID: 28090431 Free PMC article.

96

Circulating Modified Metabolites and a Risk of ESRD in Patients With Type 1 Diabetes and Chronic Kidney Disease.

Niewczas MA, Mathew AV, Croall S, Byun J, Major M, Sabisetti VS, Smiles A, Bonventre JV, Pennathur S, Krolewski AS. Niewczas MA, et al. Diabetes Care. 2017 Mar;40(3):383-390. doi: 10.2337/dc16-0173. Epub 2017 Jan 13. Diabetes Care. 2017. PMID: 28087576 Free PMC article.

97

Urine biomarkers of tubular injury do not improve on the clinical model predicting chronic kidney disease progression.

Hsu CY, Xie D, Waikar SS, Bonventre JV, Zhang X, Sabbisetti V, Mifflin TE, Coresh J, Diamantidis CJ, He J, Lora CM, Miller ER, Nelson RG, Ojo AO, Rahman M, Schelling JR, Wilson FP, Kimmel PL, Feldman HI, Vasan RS, Liu KD; CRIC Study Investigators; CKD Biomarkers Consortium. Hsu CY, et al. Kidney Int. 2017 Jan;91(1):196-203. doi: 10.1016/j.kint.2016.09.003. Epub 2016 Oct 28. Kidney Int. 2017. PMID: 28029431 Free PMC article.

98

Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells.

Morizane R, Bonventre JV. Morizane R, et al. Nat Protoc. 2017 Jan;12(1):195-207. doi: 10.1038/nprot.2016.170. Epub 2016 Dec 22. Nat Protoc. 2017. PMID: 28005067 Free PMC article.

99

ADAM17 substrate release in proximal tubule drives kidney fibrosis.

Kefaloyianni E, Muthu ML, Kaeppler J, Sun X, Sabbisetti V, Chalaris A, Rose-John S, Wong E, Sagi I, Waikar SS, Rennke H, Humphreys BD, Bonventre JV, Herrlich A. Kefaloyianni E, et al. JCI Insight. 2016 Aug 18;1(13):87023. doi: 10.1172/jci.insight.87023. JCI Insight. 2016. PMID: 27642633 Free PMC article.

100

Endothelial Glycocalyx: Not Just a Sugar Coat.

Li L, Bonventre JV. Li L, et al. Am J Respir Crit Care Med. 2016 Aug 15;194(4):390-3. doi: 10.1164/rccm.201603-0624ED. Am J Respir Crit Care Med. 2016. PMID: 27525457 Free PMC article. No abstract available.

101

Haptoglobin or Hemopexin Therapy Prevents Acute Adverse Effects of Resuscitation After Prolonged Storage of Red Cells.

Graw JA, Mayeur C, Rosales I, Liu Y, Sabbisetti VS, Riley FE, Rechester O, Malhotra R, Warren HS, Colvin RB, Bonventre JV, Bloch DB, Zapol WM. Graw JA, et al. Circulation. 2016 Sep 27;134(13):945-60. doi: 10.1161/CIRCULATIONAHA.115.019955. Epub 2016 Aug 11. Circulation. 2016. PMID: 27515135 Free PMC article.

102

Gα12 is required for renal cystogenesis induced by Pkd1 inactivation.

Wu Y, Xu JX, El-Jouni W, Lu T, Li S, Wang Q, Tran M, Yu W, Wu M, Barrera IE, Bonventre JV, Zhou J, Denker BM, Kong T. Wu Y, et al. J Cell Sci. 2016 Oct 1;129(19):3675-3684. doi: 10.1242/jcs.190496. Epub 2016 Aug 5. J Cell Sci. 2016. PMID: 27505895 Free PMC article.

103

The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation.

Wang X, Shaw DK, Hammond HL, Sutterwala FS, Rayamajhi M, Shirey KA, Perkins DJ, Bonventre JV, Velayutham TS, Evans SM, Rodino KG, VieBrock L, Scanlon KM, Carbonetti NH, Carlyon JA, Miao EA, McBride JW, Kotsyfakis M, Pedra JH. Wang X, et al. PLoS Pathog. 2016 Aug 2;12(8):e1005803. doi: 10.1371/journal.ppat.1005803. eCollection 2016 Aug. PLoS Pathog. 2016. PMID: 27482714 Free PMC article.

104

Environmental exposure to arsenic and chromium in children is associated with kidney injury molecule-1.

Cárdenas-González M, Osorio-Yáñez C, Gaspar-Ramírez O, Pavković M, Ochoa-Martínez A, López-Ventura D, Medeiros M, Barbier OC, Pérez-Maldonado IN, Sabbisetti VS, Bonventre JV, Vaidya VS. Cárdenas-González M, et al. Environ Res. 2016 Oct;150:653-662. doi: 10.1016/j.envres.2016.06.032. Epub 2016 Jul 15. Environ Res. 2016. PMID: 27431456 Free PMC article.

105

Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies.

Waikar SS, Sabbisetti V, Ärnlöv J, Carlsson AC, Coresh J, Feldman HI, Foster MC, Fufaa GD, Helmersson-Karlqvist J, Hsu CY, Kimmel PL, Larsson A, Liu Y, Lind L, Liu KD, Mifflin TE, Nelson RG, Risérus U, Vasan RS, Xie D, Zhang X, Bonventre JV; Chronic Kidney Disease Biomarkers Consortium Investigators. Waikar SS, et al. Nephrol Dial Transplant. 2016 Sep;31(9):1460-70. doi: 10.1093/ndt/gfw203. Epub 2016 Jun 7. Nephrol Dial Transplant. 2016. PMID: 27270293 Free PMC article.

106

High-resolution renal perfusion mapping using contrast-enhanced ultrasonography in ischemia-reperfusion injury monitors changes in renal microperfusion.

Fischer K, Meral FC, Zhang Y, Vangel MG, Jolesz FA, Ichimura T, Bonventre JV. Fischer K, et al. Kidney Int. 2016 Jun;89(6):1388-98. doi: 10.1016/j.kint.2016.02.004. Epub 2016 Mar 25. Kidney Int. 2016. PMID: 27165821 Free PMC article.

107

Kidney tubules: intertubular, vascular, and glomerular cross-talk.

Ferenbach DA, Bonventre JV. Ferenbach DA, et al. Curr Opin Nephrol Hypertens. 2016 May;25(3):194-202. doi: 10.1097/MNH.0000000000000218. Curr Opin Nephrol Hypertens. 2016. PMID: 27023838 Free PMC article. Review.

108

Acute kidney injury and chronic kidney disease: From the laboratory to the clinic.

Ferenbach DA, Bonventre JV. Ferenbach DA, et al. Nephrol Ther. 2016 Apr;12 Suppl 1(Suppl 1):S41-8. doi: 10.1016/j.nephro.2016.02.005. Epub 2016 Mar 10. Nephrol Ther. 2016. PMID: 26972097 Free PMC article. Review.

109

Fibroblast growth factor 23 levels are elevated and associated with severe acute kidney injury and death following cardiac surgery.

Leaf DE, Christov M, Jüppner H, Siew E, Ikizler TA, Bian A, Chen G, Sabbisetti VS, Bonventre JV, Cai X, Wolf M, Waikar SS. Leaf DE, et al. Kidney Int. 2016 Apr;89(4):939-48. doi: 10.1016/j.kint.2015.12.035. Epub 2016 Feb 17. Kidney Int. 2016. PMID: 26924052 Free PMC article.

110

Acute Kidney Injury.

Zuk A, Bonventre JV. Zuk A, et al. Annu Rev Med. 2016;67:293-307. doi: 10.1146/annurev-med-050214-013407. Annu Rev Med. 2016. PMID: 26768243 Free PMC article. Review.

111

G protein α₁₂ (Gα₁₂) is a negative regulator of kidney injury molecule-1-mediated efferocytosis.

Ismail OZ, Zhang X, Bonventre JV, Gunaratnam L. Ismail OZ, et al. Am J Physiol Renal Physiol. 2016 Apr 1;310(7):F607-F620. doi: 10.1152/ajprenal.00169.2015. Epub 2015 Dec 23. Am J Physiol Renal Physiol. 2016. PMID: 26697979 Free PMC article.

112

KIM-1/TIM-1 in proximal tubular cell immune response.

Brooks CR, Bonventre JV. Brooks CR, et al. Oncotarget. 2015 Dec 29;6(42):44059-60. doi: 10.18632/oncotarget.6623. Oncotarget. 2015. PMID: 26683362 Free PMC article. No abstract available.

113

Cytosolic phospholipase A2α regulates G1 progression through modulating FOXO1 activity.

Naini SM, Choukroun GJ, Ryan JR, Hentschel DM, Shah JV, Bonventre JV. Naini SM, et al. FASEB J. 2016 Mar;30(3):1155-70. doi: 10.1096/fj.15-278416. Epub 2015 Dec 7. FASEB J. 2016. PMID: 26644349 Free PMC article.

114

Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage.

Suzuki T, Yamaguchi H, Kikusato M, Hashizume O, Nagatoishi S, Matsuo A, Sato T, Kudo T, Matsuhashi T, Murayama K, Ohba Y, Watanabe S, Kanno S, Minaki D, Saigusa D, Shinbo H, Mori N, Yuri A, Yokoro M, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Kikuchi K, Toyohara T, Suzuki C, Ichimura T, Anzai J, Kohzuki M, Mano N, Kure S, Yanagisawa T, Tomioka Y, Toyomizu M, Tsumoto K, Nakada K, Bonventre JV, Ito S, Osaka H, Hayashi K, Abe T. Suzuki T, et al. J Am Soc Nephrol. 2016 Jul;27(7):1925-32. doi: 10.1681/ASN.2015060623. Epub 2015 Nov 25. J Am Soc Nephrol. 2016. PMID: 26609120 Free PMC article.

115

Inflammation in AKI: Current Understanding, Key Questions, and Knowledge Gaps.

Rabb H, Griffin MD, McKay DB, Swaminathan S, Pickkers P, Rosner MH, Kellum JA, Ronco C; Acute Dialysis Quality Initiative Consensus XIII Work Group. Rabb H, et al. J Am Soc Nephrol. 2016 Feb;27(2):371-9. doi: 10.1681/ASN.2015030261. Epub 2015 Nov 11. J Am Soc Nephrol. 2016. PMID: 26561643 Free PMC article. Review.

116

Mammalian Target of Rapamycin Mediates Kidney Injury Molecule 1-Dependent Tubule Injury in a Surrogate Model.

Yin W, Naini SM, Chen G, Hentschel DM, Humphreys BD, Bonventre JV. Yin W, et al. J Am Soc Nephrol. 2016 Jul;27(7):1943-57. doi: 10.1681/ASN.2015050500. Epub 2015 Nov 4. J Am Soc Nephrol. 2016. PMID: 26538632 Free PMC article.

117

Progression after AKI: Understanding Maladaptive Repair Processes to Predict and Identify Therapeutic Treatments.

Basile DP, Bonventre JV, Mehta R, Nangaku M, Unwin R, Rosner MH, Kellum JA, Ronco C; ADQI XIII Work Group. Basile DP, et al. J Am Soc Nephrol. 2016 Mar;27(3):687-97. doi: 10.1681/ASN.2015030309. Epub 2015 Oct 30. J Am Soc Nephrol. 2016. PMID: 26519085 Free PMC article.

118

Increased plasma kidney injury molecule-1 suggests early progressive renal decline in non-proteinuric patients with type 1 diabetes.

Nowak N, Skupien J, Niewczas MA, Yamanouchi M, Major M, Croall S, Smiles A, Warram JH, Bonventre JV, Krolewski AS. Nowak N, et al. Kidney Int. 2016 Feb;89(2):459-67. doi: 10.1038/ki.2015.314. Kidney Int. 2016. PMID: 26509588 Free PMC article.

119

Meclizine Preconditioning Protects the Kidney Against Ischemia-Reperfusion Injury.

Kishi S, Campanholle G, Gohil VM, Perocchi F, Brooks CR, Morizane R, Sabbisetti V, Ichimura T, Mootha VK, Bonventre JV. Kishi S, et al. EBioMedicine. 2015 Jul 29;2(9):1090-101. doi: 10.1016/j.ebiom.2015.07.035. eCollection 2015 Sep. EBioMedicine. 2015. PMID: 26501107 Free PMC article.

120

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids.

Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, Musunuru K, McNagny KM, Steinman TI, Zhou J, Lerou PH, Bonventre JV. Freedman BS, et al. Nat Commun. 2015 Oct 23;6:8715. doi: 10.1038/ncomms9715. Nat Commun. 2015. PMID: 26493500 Free PMC article.

121

Nephron organoids derived from human pluripotent stem cells model kidney development and injury.

Morizane R, Lam AQ, Freedman BS, Kishi S, Valerius MT, Bonventre JV. Morizane R, et al. Nat Biotechnol. 2015 Nov;33(11):1193-200. doi: 10.1038/nbt.3392. Nat Biotechnol. 2015. PMID: 26458176 Free PMC article.

122

Urinary kidney injury molecule-1 and monocyte chemotactic protein-1 are noninvasive biomarkers of cisplatin-induced nephrotoxicity in lung cancer patients.

Shinke H, Masuda S, Togashi Y, Ikemi Y, Ozawa A, Sato T, Kim YH, Mishima M, Ichimura T, Bonventre JV, Matsubara K. Shinke H, et al. Cancer Chemother Pharmacol. 2015 Nov;76(5):989-96. doi: 10.1007/s00280-015-2880-y. Epub 2015 Sep 25. Cancer Chemother Pharmacol. 2015. PMID: 26407820 Free PMC article. Clinical Trial.

123

Urinary Biomarkers and Risk of ESRD in the Atherosclerosis Risk in Communities Study.

Foster MC, Coresh J, Bonventre JV, Sabbisetti VS, Waikar SS, Mifflin TE, Nelson RG, Grams M, Feldman HI, Vasan RS, Kimmel PL, Hsu CY, Liu KD; CKD Biomarkers Consortium. Foster MC, et al. Clin J Am Soc Nephrol. 2015 Nov 6;10(11):1956-63. doi: 10.2215/CJN.02590315. Epub 2015 Sep 8. Clin J Am Soc Nephrol. 2015. PMID: 26350438 Free PMC article.

124

Primary proximal tubule injury leads to epithelial cell cycle arrest, fibrosis, vascular rarefaction, and glomerulosclerosis.

Bonventre JV. Bonventre JV. Kidney Int Suppl (2011). 2014 Nov;4(1):39-44. doi: 10.1038/kisup.2014.8. Kidney Int Suppl (2011). 2014. PMID: 26310195 Free PMC article. Review.

125

Group IVA Cytosolic Phospholipase A2 Regulates the G2-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2.

Movahedi Naini S, Sheridan AM, Force T, Shah JV, Bonventre JV. Movahedi Naini S, et al. Mol Cell Biol. 2015 Nov;35(21):3768-84. doi: 10.1128/MCB.00184-15. Epub 2015 Aug 24. Mol Cell Biol. 2015. PMID: 26303530 Free PMC article.

126

KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation.

Brooks CR, Yeung MY, Brooks YS, Chen H, Ichimura T, Henderson JM, Bonventre JV. Brooks CR, et al. EMBO J. 2015 Oct 1;34(19):2441-64. doi: 10.15252/embj.201489838. Epub 2015 Aug 17. EMBO J. 2015. PMID: 26282792 Free PMC article.

127

Acute kidney injury: Can remote ischaemic preconditioning prevent AKI?

Zuk A, Bonventre JV. Zuk A, et al. Nat Rev Nephrol. 2015 Sep;11(9):512-3. doi: 10.1038/nrneph.2015.119. Epub 2015 Jul 28. Nat Rev Nephrol. 2015. PMID: 26215511 Free PMC article.

128

Cytosolic Phospholipase A2α Is Essential for Renal Dysfunction and End-Organ Damage Associated With Angiotensin II-Induced Hypertension.

Khan NS, Song CY, Thirunavukkarasu S, Fang XR, Bonventre JV, Malik KU. Khan NS, et al. Am J Hypertens. 2016 Feb;29(2):258-65. doi: 10.1093/ajh/hpv083. Epub 2015 Jun 4. Am J Hypertens. 2016. PMID: 26045535 Free PMC article.

129

Clear cell papillary renal cell carcinoma and renal angiomyoadenomatous tumor: two variants of a morphologic, immunohistochemical, and genetic distinct entity of renal cell carcinoma.

Deml KF, Schildhaus HU, Compérat E, von Teichman A, Storz M, Schraml P, Bonventre JV, Fend F, Fleige B, Nerlich A, Gabbert HE, GaBler N, Grobholz R, Hailemariam S, Hinze R, Knüchel R, Lhermitte B, Nesi G, Rüdiger T, Sauter G, Moch H. Deml KF, et al. Am J Surg Pathol. 2015 Jul;39(7):889-901. doi: 10.1097/PAS.0000000000000456. Am J Surg Pathol. 2015. PMID: 25970683 Free PMC article.

130

Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen-Induced Liver Injury.

Antoine DJ, Sabbisetti VS, Francis B, Jorgensen AL, Craig DG, Simpson KJ, Bonventre JV, Park BK, Dear JW. Antoine DJ, et al. Hepatology. 2015 Aug;62(2):591-9. doi: 10.1002/hep.27857. Epub 2015 May 29. Hepatology. 2015. PMID: 25891479 Free PMC article.

131

KIM-1-mediated phagocytosis reduces acute injury to the kidney.

Yang L, Brooks CR, Xiao S, Sabbisetti V, Yeung MY, Hsiao LL, Ichimura T, Kuchroo V, Bonventre JV. Yang L, et al. J Clin Invest. 2015 Apr;125(4):1620-36. doi: 10.1172/JCI75417. Epub 2015 Mar 9. J Clin Invest. 2015. PMID: 25751064 Free PMC article.

132

Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium.

Hsu CY, Ballard S, Batlle D, Bonventre JV, Böttinger EP, Feldman HI, Klein JB, Coresh J, Eckfeldt JH, Inker LA, Kimmel PL, Kusek JW, Liu KD, Mauer M, Mifflin TE, Molitch ME, Nelsestuen GL, Rebholz CM, Rovin BH, Sabbisetti VS, Van Eyk JE, Vasan RS, Waikar SS, Whitehead KM, Nelson RG; CKD Biomarkers Consortium. Hsu CY, et al. Clin J Am Soc Nephrol. 2015 May 7;10(5):894-902. doi: 10.2215/CJN.11541114. Epub 2015 Mar 4. Clin J Am Soc Nephrol. 2015. PMID: 25739849 Free PMC article. Review.

133

Regenerating the nephron with human pluripotent stem cells.

Lam AQ, Bonventre JV. Lam AQ, et al. Curr Opin Organ Transplant. 2015 Apr;20(2):187-92. doi: 10.1097/MOT.0000000000000177. Curr Opin Organ Transplant. 2015. PMID: 25695593 Review.

134

Cytosolic phospholipase A2α is critical for angiotensin II-induced hypertension and associated cardiovascular pathophysiology.

Khan NS, Song CY, Jennings BL, Estes AM, Fang XR, Bonventre JV, Malik KU. Khan NS, et al. Hypertension. 2015 Apr;65(4):784-92. doi: 10.1161/HYPERTENSIONAHA.114.04803. Epub 2015 Feb 9. Hypertension. 2015. PMID: 25667212 Free PMC article.

135

TIM-1 signaling is required for maintenance and induction of regulatory B cells.

Yeung MY, Ding Q, Brooks CR, Xiao S, Workman CJ, Vignali DA, Ueno T, Padera RF, Kuchroo VK, Najafian N, Rothstein DM. Yeung MY, et al. Am J Transplant. 2015 Apr;15(4):942-53. doi: 10.1111/ajt.13087. Epub 2015 Feb 2. Am J Transplant. 2015. PMID: 25645598 Free PMC article.

136

Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD.

Ferenbach DA, Bonventre JV. Ferenbach DA, et al. Nat Rev Nephrol. 2015 May;11(5):264-76. doi: 10.1038/nrneph.2015.3. Epub 2015 Feb 3. Nat Rev Nephrol. 2015. PMID: 25643664 Free PMC article. Review.

137

Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis.

Besschetnova TY, Ichimura T, Katebi N, St Croix B, Bonventre JV, Olsen BR. Besschetnova TY, et al. Matrix Biol. 2015 Mar;42:56-73. doi: 10.1016/j.matbio.2014.12.002. Epub 2015 Jan 5. Matrix Biol. 2015. PMID: 25572963 Free PMC article.

138

Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells.

Xu JX, Lu TS, Li S, Wu Y, Ding L, Denker BM, Bonventre JV, Kong T. Xu JX, et al. Physiol Genomics. 2015 Feb;47(2):24-32. doi: 10.1152/physiolgenomics.00090.2014. Epub 2014 Dec 9. Physiol Genomics. 2015. PMID: 25492927 Free PMC article.

139

Cystatin C in acute kidney injury diagnosis: early biomarker or alternative to serum creatinine?

Lagos-Arevalo P, Palijan A, Vertullo L, Devarajan P, Bennett MR, Sabbisetti V, Bonventre JV, Ma Q, Gottesman RD, Zappitelli M. Lagos-Arevalo P, et al. Pediatr Nephrol. 2015 Apr;30(4):665-76. doi: 10.1007/s00467-014-2987-0. Epub 2014 Dec 5. Pediatr Nephrol. 2015. PMID: 25475610 Free PMC article.

140

RGS4 inhibits angiotensin II signaling and macrophage localization during renal reperfusion injury independent of vasospasm.

Pang P, Jin X, Proctor BM, Farley M, Roy N, Chin MS, von Andrian UH, Vollmann E, Perro M, Hoffman RJ, Chung J, Chauhan N, Mistri M, Muslin AJ, Bonventre JV, Siedlecki AM. Pang P, et al. Kidney Int. 2015 Apr;87(4):771-83. doi: 10.1038/ki.2014.364. Epub 2014 Dec 3. Kidney Int. 2015. PMID: 25469849 Free PMC article.

141

Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus.

Fufaa GD, Weil EJ, Nelson RG, Hanson RL, Bonventre JV, Sabbisetti V, Waikar SS, Mifflin TE, Zhang X, Xie D, Hsu CY, Feldman HI, Coresh J, Vasan RS, Kimmel PL, Liu KD; Chronic Kidney Disease Biomarkers Consortium Investigators. Fufaa GD, et al. Diabetologia. 2015 Jan;58(1):188-98. doi: 10.1007/s00125-014-3389-3. Epub 2014 Oct 15. Diabetologia. 2015. PMID: 25316431 Free PMC article.

142

The aging kidney: increased susceptibility to nephrotoxicity.

Wang X, Bonventre JV, Parrish AR. Wang X, et al. Int J Mol Sci. 2014 Sep 1;15(9):15358-76. doi: 10.3390/ijms150915358. Int J Mol Sci. 2014. PMID: 25257519 Free PMC article. Review.

143

The kidney research national dialogue: gearing up to move forward.

Bonventre JV, Boulware LE, Dember LM, Freedman BI, Furth SL, Holzman LB, Ketchum CJ, Little MH, Mehrotra R, Moe SM, Sands JM, Sedor JR, Somlo S, Star RA, Rys-Sikora KE; Kidney Research National Dialogue (KRND). Bonventre JV, et al. Clin J Am Soc Nephrol. 2014 Oct 7;9(10):1806-11. doi: 10.2215/CJN.07310714. Epub 2014 Sep 15. Clin J Am Soc Nephrol. 2014. PMID: 25225184 Free PMC article. Review.

144

Directed differentiation of pluripotent stem cells to kidney cells.

Lam AQ, Freedman BS, Bonventre JV. Lam AQ, et al. Semin Nephrol. 2014 Jul;34(4):445-61. doi: 10.1016/j.semnephrol.2014.06.011. Epub 2014 Jun 13. Semin Nephrol. 2014. PMID: 25217273 Free PMC article. Review.

145

Kidney injury molecule-1: a translational journey.

Bonventre JV. Bonventre JV. Trans Am Clin Climatol Assoc. 2014;125:293-9; discussion 299. Trans Am Clin Climatol Assoc. 2014. PMID: 25125746 Free PMC article. Review.

146

Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury.

Canaud G, Bonventre JV. Canaud G, et al. Nephrol Dial Transplant. 2015 Apr;30(4):575-83. doi: 10.1093/ndt/gfu230. Epub 2014 Jul 12. Nephrol Dial Transplant. 2015. PMID: 25016609 Free PMC article. Review.

147

Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo.

Grgic I, Hofmeister AF, Genovese G, Bernhardy AJ, Sun H, Maarouf OH, Bijol V, Pollak MR, Humphreys BD. Grgic I, et al. Kidney Int. 2014 Dec;86(6):1116-29. doi: 10.1038/ki.2014.204. Epub 2014 Jun 18. Kidney Int. 2014. PMID: 24940801 Free PMC article.

148

Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes.

Sabbisetti VS, Waikar SS, Antoine DJ, Smiles A, Wang C, Ravisankar A, Ito K, Sharma S, Ramadesikan S, Lee M, Briskin R, De Jager PL, Ngo TT, Radlinski M, Dear JW, Park KB, Betensky R, Krolewski AS, Bonventre JV. Sabbisetti VS, et al. J Am Soc Nephrol. 2014 Oct;25(10):2177-86. doi: 10.1681/ASN.2013070758. Epub 2014 Jun 5. J Am Soc Nephrol. 2014. PMID: 24904085 Free PMC article.

149

Conformational change in transfer RNA is an early indicator of acute cellular damage.

Mishima E, Inoue C, Saigusa D, Inoue R, Ito K, Suzuki Y, Jinno D, Tsukui Y, Akamatsu Y, Araki M, Araki K, Shimizu R, Shinke H, Suzuki T, Takeuchi Y, Shima H, Akiyama Y, Toyohara T, Suzuki C, Saiki Y, Tominaga T, Miyagi S, Kawagisihi N, Soga T, Ohkubo T, Yamamura K, Imai Y, Masuda S, Sabbisetti V, Ichimura T, Mount DB, Bonventre JV, Ito S, Tomioka Y, Itoh K, Abe T. Mishima E, et al. J Am Soc Nephrol. 2014 Oct;25(10):2316-26. doi: 10.1681/ASN.2013091001. Epub 2014 May 15. J Am Soc Nephrol. 2014. PMID: 24833129 Free PMC article.

150

Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis.

Gandhi R, Yi J, Ha J, Shi H, Ismail O, Nathoo S, Bonventre JV, Zhang X, Gunaratnam L. Gandhi R, et al. Am J Physiol Renal Physiol. 2014 Jul 15;307(2):F205-21. doi: 10.1152/ajprenal.00638.2013. Epub 2014 May 14. Am J Physiol Renal Physiol. 2014. PMID: 24829508 Free PMC article.

151

Stigmata of death: for kidneys and patients.

Ronco C, Bonventre JV. Ronco C, et al. Nephrol Dial Transplant. 2014 Oct;29(10):1797-8. doi: 10.1093/ndt/gfu103. Epub 2014 May 2. Nephrol Dial Transplant. 2014. PMID: 24792373 Free PMC article. No abstract available.

152

Positive effects of a novel non-peptidyl low molecular weight radical scavenger in renal ischemia/reperfusion: a preliminary report.

Bassi R, Vergani A, D'Addio F, Ben Nasr M, Mocci A, Rastaldi MP, Ichimura T, Bonventre JV, Fiorina P. Bassi R, et al. Springerplus. 2014 Mar 24;3:158. doi: 10.1186/2193-1801-3-158. eCollection 2014. Springerplus. 2014. PMID: 24741476 Free PMC article.

153

Reference intervals for urinary renal injury biomarkers KIM-1 and NGAL in healthy children.

McWilliam SJ, Antoine DJ, Sabbisetti V, Pearce RE, Jorgensen AL, Lin Y, Leeder JS, Bonventre JV, Smyth RL, Pirmohamed M. McWilliam SJ, et al. Biomark Med. 2014;8(10):1189-97. doi: 10.2217/bmm.14.36. Biomark Med. 2014. PMID: 24661102 Free PMC article.

154

Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study.

Niewczas MA, Sirich TL, Mathew AV, Skupien J, Mohney RP, Warram JH, Smiles A, Huang X, Walker W, Byun J, Karoly ED, Kensicki EM, Berry GT, Bonventre JV, Pennathur S, Meyer TW, Krolewski AS. Niewczas MA, et al. Kidney Int. 2014 May;85(5):1214-24. doi: 10.1038/ki.2013.497. Epub 2014 Jan 15. Kidney Int. 2014. PMID: 24429397 Free PMC article.

155

Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers.

Lam AQ, Freedman BS, Morizane R, Lerou PH, Valerius MT, Bonventre JV. Lam AQ, et al. J Am Soc Nephrol. 2014 Jun;25(6):1211-25. doi: 10.1681/ASN.2013080831. Epub 2013 Dec 19. J Am Soc Nephrol. 2014. PMID: 24357672 Free PMC article.

156

Urinary expression of novel tissue markers of kidney injury after ureteroscopy, shockwave lithotripsy, and in normal healthy controls.

Fahmy N, Sener A, Sabbisetti V, Nott L, Lang RM, Welk BK, Méndez-Probst CE, MacPhee RA, VanEerdewijk S, Cadieux PA, Bonventre JV, Razvi H. Fahmy N, et al. J Endourol. 2013 Dec;27(12):1455-62. doi: 10.1089/end.2013.0188. Epub 2013 Nov 1. J Endourol. 2013. PMID: 24180435 Free PMC article.

157

Antifibrotic vitamin D analogs.

Bonventre JV. Bonventre JV. J Clin Invest. 2013 Nov;123(11):4570-3. doi: 10.1172/JCI72748. Epub 2013 Oct 25. J Clin Invest. 2013. PMID: 24162671 Free PMC article.

158

Reduced ciliary polycystin-2 in induced pluripotent stem cells from polycystic kidney disease patients with PKD1 mutations.

Freedman BS, Lam AQ, Sundsbak JL, Iatrino R, Su X, Koon SJ, Wu M, Daheron L, Harris PC, Zhou J, Bonventre JV. Freedman BS, et al. J Am Soc Nephrol. 2013 Oct;24(10):1571-86. doi: 10.1681/ASN.2012111089. Epub 2013 Sep 5. J Am Soc Nephrol. 2013. PMID: 24009235 Free PMC article.

159

Imperfect gold standards for biomarker evaluation.

Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Waikar SS, et al. Clin Trials. 2013 Oct;10(5):696-700. doi: 10.1177/1740774513497540. Epub 2013 Sep 3. Clin Trials. 2013. PMID: 24006246 Free PMC article.

160

Urine kidney injury molecule-1: a potential non-invasive biomarker for patients with renal cell carcinoma.

Zhang PL, Mashni JW, Sabbisetti VS, Schworer CM, Wilson GD, Wolforth SC, Kernen KM, Seifman BD, Amin MB, Geddes TJ, Lin F, Bonventre JV, Hafron JM. Zhang PL, et al. Int Urol Nephrol. 2014 Feb;46(2):379-88. doi: 10.1007/s11255-013-0522-z. Epub 2013 Aug 25. Int Urol Nephrol. 2014. PMID: 23979814 Free PMC article.

161

Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis.

Humphreys BD, Xu F, Sabbisetti V, Grgic I, Movahedi Naini S, Wang N, Chen G, Xiao S, Patel D, Henderson JM, Ichimura T, Mou S, Soeung S, McMahon AP, Kuchroo VK, Bonventre JV. Humphreys BD, et al. J Clin Invest. 2013 Sep;123(9):4023-35. doi: 10.1172/JCI45361. Epub 2013 Aug 27. J Clin Invest. 2013. PMID: 23979159 Free PMC article.

162

AKI: a path forward.

Bonventre JV, Basile D, Liu KD, McKay D, Molitoris BA, Nath KA, Nickolas TL, Okusa MD, Palevsky PM, Schnellmann R, Rys-Sikora K, Kimmel PL, Star RA; Kidney Research National Dialogue (KRND). Bonventre JV, et al. Clin J Am Soc Nephrol. 2013 Sep;8(9):1606-8. doi: 10.2215/CJN.06040613. Epub 2013 Jul 18. Clin J Am Soc Nephrol. 2013. PMID: 23868899 Free PMC article.

163

Tumor necrosis factor alpha promoter polymorphism and severity of acute kidney injury.

Susantitaphong P, Perianayagam MC, Tighiouart H, Liangos O, Bonventre JV, Jaber BL. Susantitaphong P, et al. Nephron Clin Pract. 2013;123(1-2):67-73. doi: 10.1159/000351684. Epub 2013 Jun 21. Nephron Clin Pract. 2013. PMID: 23796916 Free PMC article.

164

Multipotent mesenchymal stromal cells protect against kidney injury.

Tögel FE, Bonventre JV. Tögel FE, et al. Cytotherapy. 2013 Jun;15(6):629-31. doi: 10.1016/j.jcyt.2013.04.005. Cytotherapy. 2013. PMID: 23643304 Free PMC article. No abstract available.

165

Flow is critical for maintaining a protective phenotype in renal proximal tubular cells.

Timsit MO, Adams WJ, Laguna-Fernandez A, Ichimura T, Bonventre JV, García-Cardeña G, Tullius SG. Timsit MO, et al. Am J Transplant. 2013 Jun;13(6):1617-8. doi: 10.1111/ajt.12242. Epub 2013 Apr 25. Am J Transplant. 2013. PMID: 23617882 Free PMC article. No abstract available.

166

Meaningful measurement: developing a measurement system to improve blood pressure control in patients with chronic kidney disease.

Greenberg JO, Vakharia N, Szent-Gyorgyi LE, Desai SP, Turchin A, Forman J, Bonventre JV, Kachalia A. Greenberg JO, et al. J Am Med Inform Assoc. 2013 Jun;20(e1):e97-e101. doi: 10.1136/amiajnl-2012-001308. Epub 2013 Jan 23. J Am Med Inform Assoc. 2013. PMID: 23345408 Free PMC article.

167

Secreted factors from bone marrow stromal cells upregulate IL-10 and reverse acute kidney injury.

Milwid JM, Ichimura T, Li M, Jiao Y, Lee J, Yarmush JS, Parekkadan B, Tilles AW, Bonventre JV, Yarmush ML. Milwid JM, et al. Stem Cells Int. 2012;2012:392050. doi: 10.1155/2012/392050. Epub 2012 Dec 19. Stem Cells Int. 2012. PMID: 23319959 Free PMC article.

168

Urinary chemokine (C-C motif) ligand 2 (monocyte chemotactic protein-1) as a tubular injury marker for early detection of cisplatin-induced nephrotoxicity.

Nishihara K, Masuda S, Shinke H, Ozawa A, Ichimura T, Yonezawa A, Nakagawa S, Inui K, Bonventre JV, Matsubara K. Nishihara K, et al. Biochem Pharmacol. 2013 Feb 15;85(4):570-82. doi: 10.1016/j.bcp.2012.12.019. Epub 2013 Jan 2. Biochem Pharmacol. 2013. PMID: 23291264 Free PMC article.

169

Can we target tubular damage to prevent renal function decline in diabetes?

Bonventre JV. Bonventre JV. Semin Nephrol. 2012 Sep;32(5):452-62. doi: 10.1016/j.semnephrol.2012.07.008. Semin Nephrol. 2012. PMID: 23062986 Free PMC article. Review.

170

High risk of ESRD in type 1 diabetes: new strategies are needed to retard progressive renal function decline.

Krolewski AS, Bonventre JV. Krolewski AS, et al. Semin Nephrol. 2012 Sep;32(5):407-14. doi: 10.1016/j.semnephrol.2012.07.002. Semin Nephrol. 2012. PMID: 23062980 Free PMC article.

171

High risk of ESRD in type 1 diabetes: call for action: introduction.

Krolewski AS, Bonventre JV. Krolewski AS, et al. Semin Nephrol. 2012 Sep;32(5):405-6. doi: 10.1016/j.semnephrol.2012.07.001. Semin Nephrol. 2012. PMID: 23062979 No abstract available.

172

Novel assays for detection of urinary KIM-1 in mouse models of kidney injury.

Sabbisetti VS, Ito K, Wang C, Yang L, Mefferd SC, Bonventre JV. Sabbisetti VS, et al. Toxicol Sci. 2013 Jan;131(1):13-25. doi: 10.1093/toxsci/kfs268. Epub 2012 Sep 27. Toxicol Sci. 2013. PMID: 23019274 Free PMC article.

173

Mechanism-based urinary biomarkers to identify the potential for aminoglycoside-induced nephrotoxicity in premature neonates: a proof-of-concept study.

McWilliam SJ, Antoine DJ, Sabbisetti V, Turner MA, Farragher T, Bonventre JV, Park BK, Smyth RL, Pirmohamed M. McWilliam SJ, et al. PLoS One. 2012;7(8):e43809. doi: 10.1371/journal.pone.0043809. Epub 2012 Aug 24. PLoS One. 2012. PMID: 22937100 Free PMC article.

174

Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.

Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK. Xiao S, et al. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12105-10. doi: 10.1073/pnas.1120914109. Epub 2012 Jul 5. Proc Natl Acad Sci U S A. 2012. PMID: 22773818 Free PMC article.

175

Associations of urinary levels of kidney injury molecule 1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) with kidney function decline in the Multi-Ethnic Study of Atherosclerosis (MESA).

Peralta CA, Katz R, Bonventre JV, Sabbisetti V, Siscovick D, Sarnak M, Shlipak MG. Peralta CA, et al. Am J Kidney Dis. 2012 Dec;60(6):904-11. doi: 10.1053/j.ajkd.2012.05.014. Epub 2012 Jun 30. Am J Kidney Dis. 2012. PMID: 22749388 Free PMC article.

176

Limb ischemia protects against contrast-induced nephropathy.

Bonventre JV. Bonventre JV. Circulation. 2012 Jul 24;126(4):384-7. doi: 10.1161/CIRCULATIONAHA.112.119701. Epub 2012 Jun 26. Circulation. 2012. PMID: 22735307 Free PMC article. No abstract available.

177

Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity.

Sengupta P, Basu S, Soni S, Pandey A, Roy B, Oh MS, Chin KT, Paraskar AS, Sarangi S, Connor Y, Sabbisetti VS, Kopparam J, Kulkarni A, Muto K, Amarasiriwardena C, Jayawardene I, Lupoli N, Dinulescu DM, Bonventre JV, Mashelkar RA, Sengupta S. Sengupta P, et al. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11294-9. doi: 10.1073/pnas.1203129109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733767 Free PMC article.

178

Elevated urinary levels of kidney injury molecule-1 among Chinese factory workers exposed to trichloroethylene.

Vermeulen R, Zhang L, Spierenburg A, Tang X, Bonventre JV, Reiss B, Shen M, Smith MT, Qiu C, Ge Y, Ji Z, Xiong J, He J, Hao Z, Liu S, Xie Y, Yue F, Guo W, Purdue M, Beane Freeman LE, Sabbisetti V, Li L, Huang H, Rothman N, Lan Q. Vermeulen R, et al. Carcinogenesis. 2012 Aug;33(8):1538-41. doi: 10.1093/carcin/bgs191. Epub 2012 Jun 4. Carcinogenesis. 2012. PMID: 22665366 Free PMC article.

179

Kim-1/Tim-1 and immune cells: shifting sands.

Ichimura T, Brooks CR, Bonventre JV. Ichimura T, et al. Kidney Int. 2012 May;81(9):809-11. doi: 10.1038/ki.2012.11. Kidney Int. 2012. PMID: 22499138 Free PMC article.

180

Evaluation of putative renal cell carcinoma markers PAX-2, PAX-8, and hKIM-1 in germ cell tumors: a tissue microarray study of 100 cases.

Sangoi AR, McKenney JK, Brooks JD, Bonventre JV, Higgins JP. Sangoi AR, et al. Appl Immunohistochem Mol Morphol. 2012 Oct;20(5):451-3. doi: 10.1097/PAI.0b013e31824bb404. Appl Immunohistochem Mol Morphol. 2012. PMID: 22495365 Free PMC article.

181

Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis.

Grgic I, Campanholle G, Bijol V, Wang C, Sabbisetti VS, Ichimura T, Humphreys BD, Bonventre JV. Grgic I, et al. Kidney Int. 2012 Jul;82(2):172-83. doi: 10.1038/ki.2012.20. Epub 2012 Mar 21. Kidney Int. 2012. PMID: 22437410 Free PMC article.

182

Some biomarkers of acute kidney injury are increased in pre-renal acute injury.

Nejat M, Pickering JW, Devarajan P, Bonventre JV, Edelstein CL, Walker RJ, Endre ZH. Nejat M, et al. Kidney Int. 2012 Jun;81(12):1254-62. doi: 10.1038/ki.2012.23. Epub 2012 Mar 14. Kidney Int. 2012. PMID: 22418979 Free PMC article.

183

Imaging of podocyte foot processes by fluorescence microscopy.

Grgic I, Brooks CR, Hofmeister AF, Bijol V, Bonventre JV, Humphreys BD. Grgic I, et al. J Am Soc Nephrol. 2012 May;23(5):785-91. doi: 10.1681/ASN.2011100988. Epub 2012 Feb 23. J Am Soc Nephrol. 2012. PMID: 22362911 Free PMC article.

184

Structural equation modeling highlights the potential of Kim-1 as a biomarker for chronic kidney disease.

Gardiner L, Akintola A, Chen G, Catania JM, Vaidya V, Burghardt RC, Bonventre JV, Trzeciakowski J, Parrish AR. Gardiner L, et al. Am J Nephrol. 2012;35(2):152-63. doi: 10.1159/000335579. Epub 2012 Jan 20. Am J Nephrol. 2012. PMID: 22269876 Free PMC article.

185

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway.

Tong Y, Giaime E, Yamaguchi H, Ichimura T, Liu Y, Si H, Cai H, Bonventre JV, Shen J. Tong Y, et al. Mol Neurodegener. 2012 Jan 9;7:2. doi: 10.1186/1750-1326-7-2. Mol Neurodegener. 2012. PMID: 22230652 Free PMC article.

186

Test characteristics of urinary biomarkers depend on quantitation method in acute kidney injury.

Ralib AM, Pickering JW, Shaw GM, Devarajan P, Edelstein CL, Bonventre JV, Endre ZH. Ralib AM, et al. J Am Soc Nephrol. 2012 Feb;23(2):322-33. doi: 10.1681/ASN.2011040325. Epub 2011 Nov 17. J Am Soc Nephrol. 2012. PMID: 22095948 Free PMC article.

187

Cellular pathophysiology of ischemic acute kidney injury.

Bonventre JV, Yang L. Bonventre JV, et al. J Clin Invest. 2011 Nov;121(11):4210-21. doi: 10.1172/JCI45161. Epub 2011 Nov 1. J Clin Invest. 2011. PMID: 22045571 Free PMC article. Review.

188

Imperfect gold standards for kidney injury biomarker evaluation.

Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Waikar SS, et al. J Am Soc Nephrol. 2012 Jan;23(1):13-21. doi: 10.1681/ASN.2010111124. Epub 2011 Oct 21. J Am Soc Nephrol. 2012. PMID: 22021710 Free PMC article.

189

Focal adhesion kinase signaling mediates acute renal injury induced by ischemia/reperfusion.

Qin Y, Alderliesten MC, Stokman G, Pennekamp P, Bonventre JV, de Heer E, Ichimura T, de Graauw M, Price LS, van de Water B. Qin Y, et al. Am J Pathol. 2011 Dec;179(6):2766-78. doi: 10.1016/j.ajpath.2011.08.025. Epub 2011 Oct 5. Am J Pathol. 2011. PMID: 21982831 Free PMC article.

190

Pathophysiology of acute kidney injury to chronic kidney disease: maladaptive repair.

Yang L, Humphreys BD, Bonventre JV. Yang L, et al. Contrib Nephrol. 2011;174:149-155. doi: 10.1159/000329385. Epub 2011 Sep 9. Contrib Nephrol. 2011. PMID: 21921619 Review.

191

Repair of injured proximal tubule does not involve specialized progenitors.

Humphreys BD, Czerniak S, DiRocco DP, Hasnain W, Cheema R, Bonventre JV. Humphreys BD, et al. Proc Natl Acad Sci U S A. 2011 May 31;108(22):9226-31. doi: 10.1073/pnas.1100629108. Epub 2011 May 16. Proc Natl Acad Sci U S A. 2011. PMID: 21576461 Free PMC article.

192

Immunohistochemical distinction of primary adrenal cortical lesions from metastatic clear cell renal cell carcinoma: a study of 248 cases.

Sangoi AR, Fujiwara M, West RB, Montgomery KD, Bonventre JV, Higgins JP, Rouse RV, Gokden N, McKenney JK. Sangoi AR, et al. Am J Surg Pathol. 2011 May;35(5):678-86. doi: 10.1097/PAS.0b013e3182152629. Am J Surg Pathol. 2011. PMID: 21490444 Free PMC article.

193

Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function.

Endre ZH, Pickering JW, Walker RJ, Devarajan P, Edelstein CL, Bonventre JV, Frampton CM, Bennett MR, Ma Q, Sabbisetti VS, Vaidya VS, Walcher AM, Shaw GM, Henderson SJ, Nejat M, Schollum JB, George PM. Endre ZH, et al. Kidney Int. 2011 May;79(10):1119-30. doi: 10.1038/ki.2010.555. Epub 2011 Feb 9. Kidney Int. 2011. PMID: 21307838 Free PMC article.

194

The Sweet Pee model for Sglt2 mutation.

Ly JP, Onay T, Sison K, Sivaskandarajah G, Sabbisetti V, Li L, Bonventre JV, Flenniken A, Paragas N, Barasch JM, Adamson SL, Osborne L, Rossant J, Schnermann J, Quaggin SE. Ly JP, et al. J Am Soc Nephrol. 2011 Jan;22(1):113-23. doi: 10.1681/ASN.2010080888. J Am Soc Nephrol. 2011. PMID: 21209254 Free PMC article.

195

Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-β-D-glucosaminidase.

Vaidya VS, Niewczas MA, Ficociello LH, Johnson AC, Collings FB, Warram JH, Krolewski AS, Bonventre JV. Vaidya VS, et al. Kidney Int. 2011 Feb;79(4):464-70. doi: 10.1038/ki.2010.404. Epub 2010 Oct 27. Kidney Int. 2011. PMID: 20980978 Free PMC article.

196

Kidney injury molecule-1.

Bonventre JV, Yang L. Bonventre JV, et al. Curr Opin Crit Care. 2010 Dec;16(6):556-61. doi: 10.1097/MCC.0b013e32834008d3. Curr Opin Crit Care. 2010. PMID: 20930626 Review.

197

Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury.

Koyner JL, Vaidya VS, Bennett MR, Ma Q, Worcester E, Akhter SA, Raman J, Jeevanandam V, O'Connor MF, Devarajan P, Bonventre JV, Murray PT. Koyner JL, et al. Clin J Am Soc Nephrol. 2010 Dec;5(12):2154-65. doi: 10.2215/CJN.00740110. Epub 2010 Aug 26. Clin J Am Soc Nephrol. 2010. PMID: 20798258 Free PMC article.

198

The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair.

Li B, Castano AP, Hudson TE, Nowlin BT, Lin SL, Bonventre JV, Swanson KD, Duffield JS. Li B, et al. FASEB J. 2010 Dec;24(12):4767-81. doi: 10.1096/fj.10-154757. Epub 2010 Aug 13. FASEB J. 2010. PMID: 20709912 Free PMC article.

199

TIM2 gene deletion results in susceptibility to cisplatin-induced kidney toxicity.

Krishnamoorthy A, Clement ME, O'Leary E, Bonventre JV, Vaidya VS. Krishnamoorthy A, et al. Toxicol Sci. 2010 Nov;118(1):298-306. doi: 10.1093/toxsci/kfq240. Epub 2010 Aug 11. Toxicol Sci. 2010. PMID: 20702592 Free PMC article.

200

Tubular damage in chronic systolic heart failure is associated with reduced survival independent of glomerular filtration rate.

Damman K, Van Veldhuisen DJ, Navis G, Vaidya VS, Smilde TD, Westenbrink BD, Bonventre JV, Voors AA, Hillege HL. Damman K, et al. Heart. 2010 Aug;96(16):1297-302. doi: 10.1136/hrt.2010.194878. Heart. 2010. PMID: 20659949 Free PMC article.

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