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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 5
1946 21
1947 23
1948 27
1949 31
1950 36
1951 47
1952 37
1953 27
1954 28
1955 23
1956 42
1957 31
1958 36
1959 31
1960 39
1961 39
1962 40
1963 78
1964 118
1965 154
1966 309
1967 378
1968 397
1969 353
1970 421
1971 353
1972 399
1973 492
1974 602
1975 672
1976 706
1977 879
1978 1686
1979 1946
1980 16808
1981 35160
1982 36317
1983 36924
1984 38476
1985 39388
1986 40504
1987 41878
1988 43160
1989 44898
1990 47096
1991 48861
1992 49393
1993 49944
1994 51400
1995 52130
1996 52412
1997 52989
1998 54471
1999 55806
2000 58001
2001 59524
2002 62691
2003 67279
2004 74941
2005 81897
2006 90993
2007 97599
2008 107892
2009 114078
2010 123448
2011 132887
2012 137845
2013 143230
2014 144728
2015 145441
2016 140176
2017 133993
2018 135160
2019 135261
2020 146933
2021 151668
2022 131306
2023 49649

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3,259,452 results

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Filters applied: . Clear all The following term was not found in PubMed: R01HL130129
Page 1
Synaptic memory and CaMKII: a review.
Nicoll RA, Schulman H. Nicoll RA, et al. Physiol Rev. 2023 Jun 8. doi: 10.1152/physrev.00034.2022. Online ahead of print. Physiol Rev. 2023. PMID: 37290118 Review.
Evaluating peer review at NIH.
Altman M, Cohen PN. Altman M, et al. Science. 2023 Jun 9;380(6649):1022. doi: 10.1126/science.adi1570. Epub 2023 Jun 8. Science. 2023. PMID: 37289880 No abstract available.
Correlating continuously captured home-based digital biomarkers of daily function with postmortem neurodegenerative neuropathology.
Hantke NC, Kaye J, Mattek N, Wu CY, Dodge HH, Beattie Z, Woltjer R. Hantke NC, et al. PLoS One. 2023 Jun 8;18(6):e0286812. doi: 10.1371/journal.pone.0286812. eCollection 2023. PLoS One. 2023. PMID: 37289845
BACKGROUND: Outcome measures available for use in Alzheimer's disease (AD) clinical trials are limited in ability to detect gradual changes. ...METHODS: Participants included in this study were 65 years of age, living independently, of average health for age, and fo …
BACKGROUND: Outcome measures available for use in Alzheimer's disease (AD) clinical trials are limited in ability to detect gradual c …
Contrastive learning in protein language space predicts interactions between drugs and protein targets.
Singh R, Sledzieski S, Bryson B, Cowen L, Berger B. Singh R, et al. Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2220778120. doi: 10.1073/pnas.2220778120. Epub 2023 Jun 8. Proc Natl Acad Sci U S A. 2023. PMID: 37289807
It makes predictions of binding based on the distance between learned representations, enabling predictions at the scale of massive compound libraries and the human proteome. Experimental testing of 19 kinase-drug interaction predictions validated 12 interactions, includin …
It makes predictions of binding based on the distance between learned representations, enabling predictions at the scale of massive compound …
Missing data approaches in longitudinal studies of aging: A case example using the National Health and Aging Trends Study.
Duchesneau ED, Shmuel S, Faurot KR, Musty A, Park J, Stürmer T, Kinlaw AC, Yang YC, Lund JL. Duchesneau ED, et al. PLoS One. 2023 Jun 8;18(6):e0286984. doi: 10.1371/journal.pone.0286984. eCollection 2023. PLoS One. 2023. PMID: 37289795
We described missing data challenges and potential methodological solutions using a case example describing five-year frailty state transitions in a cohort of older adults. METHODS: We used longitudinal data from the National Health and Aging Trends Study, a nationa …
We described missing data challenges and potential methodological solutions using a case example describing five-year frailty state transiti …
Safety Monitoring of mRNA COVID-19 Vaccine Third Doses Among Children Aged 6 Months-5 Years - United States, June 17, 2022-May 7, 2023.
Hause AM, Marquez P, Zhang B, Moro PL, Myers TR, Bradley C, Bazel S, Panchanathan SS, Shimabukuro TT, Shay DK. Hause AM, et al. MMWR Morb Mortal Wkly Rep. 2023 Jun 9;72(23):621-626. doi: 10.15585/mmwr.mm7223a2. MMWR Morb Mortal Wkly Rep. 2023. PMID: 37289661
As of May 7, 2023, CDC's Advisory Committee on Immunization Practices (ACIP) recommends that all children aged 6 months-5 years receive at least 1 age-appropriate bivalent mRNA COVID-19 vaccine dose. ...To characterize the safety of a third mRNA COVID-19 vaccine dose among …
As of May 7, 2023, CDC's Advisory Committee on Immunization Practices (ACIP) recommends that all children aged 6 months-5 years recei …
Impact of HIV on COVID-19 Outcomes: A Propensity Score Matching Analysis with Varying Age Differences.
Guo S, Zhang J, Yang X, Weissman S, Olatosi B, Patel RC, Li X; N3C Consortium. Guo S, et al. AIDS Behav. 2023 Jun 8. doi: 10.1007/s10461-023-04088-y. Online ahead of print. AIDS Behav. 2023. PMID: 37289345
The data used in this study was retrieved from the COVID-19 positive cohort in National COVID Cohort Collaborative (N3C). Multivariable logistic regression models were conducted on populations that were matched using either exact matching or propensity score matching (PSM) …
The data used in this study was retrieved from the COVID-19 positive cohort in National COVID Cohort Collaborative (N3C). Multivariab …
Results of Immediate Postpartum Long Acting Reversible Contraception Provision After Expanded Reimbursement Policy Implementation at an Academic Medical Institution.
Levandowski BA, Green T, Li L, Betstadt S, Thevenet-Morrison K, Harrington A. Levandowski BA, et al. Matern Child Health J. 2023 Jun 8. doi: 10.1007/s10995-023-03738-w. Online ahead of print. Matern Child Health J. 2023. PMID: 37289295
Descriptive and bivariate statistics, including chi-square tests and Fischer's exact tests, based on cell sizes, were calculated using SAS (version9.4). ...DISCUSSION: Removing structural economic barriers for people using public insurance may increase health equity …
Descriptive and bivariate statistics, including chi-square tests and Fischer's exact tests, based on cell sizes, were calculated usin …
Gestational Weight Gain During the COVID-19 Pandemic.
McPhail A, Hare ME, Talcott GW, Little MA, Bursac Z, Krukowski RA. McPhail A, et al. Matern Child Health J. 2023 Jun 8. doi: 10.1007/s10995-023-03730-4. Online ahead of print. Matern Child Health J. 2023. PMID: 37289294
DISCUSSION: In contrast to prior research that indicated challenges with engaging in health behaviors during the COVID-19 pandemic, we found that women did not have increased GWG or higher odds of excessive GWG. ...
DISCUSSION: In contrast to prior research that indicated challenges with engaging in health behaviors during the COVID-19 pandemic, w …
AS160 expression, but not AS160 Serine-588, Threonine-642, and Serine-704 phosphorylation, is essential for elevated insulin-stimulated glucose uptake by skeletal muscle from female rats after acute exercise.
Wang H, Zheng A, Arias EB, Kwak SE, Pan X, Duan D, Cartee GD. Wang H, et al. FASEB J. 2023 Jul;37(7):e23021. doi: 10.1096/fj.202300282RR. FASEB J. 2023. PMID: 37289137
We recently found that muscle expression and phosphorylation of key sites of Akt substrate of 160 kDa (AS160; also called TBC1D4) are essential for the full-exercise effect on postexercise-ISGU (PEX-ISGU) in male rats. In striking contrast, AS160's role in increased PEX-IS …
We recently found that muscle expression and phosphorylation of key sites of Akt substrate of 160 kDa (AS160; also called TBC1D4) are essent …
Lipidomic markers for the prediction of progression from mild cognitive impairment to Alzheimer's disease.
Li W, Zhou Y, Luo Z, Tang R, Sun Y, He Q, Xia B, Lu K, Hou Q, Yuan J. Li W, et al. FASEB J. 2023 Jul;37(7):e22998. doi: 10.1096/fj.202201584RR. FASEB J. 2023. PMID: 37289136
Dementia is a well-known syndrome and Alzheimer's disease (AD) is the main cause of dementia. Lipids play a key role in the pathogenesis of AD, however, the prediction value of serum lipidomics on AD remains unclear. ...
Dementia is a well-known syndrome and Alzheimer's disease (AD) is the main cause of dementia. Lipids play a key role in the pathogene …
Clinical features, comparative imaging findings, treatment, and outcome in dogs with discospondylitis: A multi-institutional retrospective study.
Van Hoof C, Davis NA, Carrera-Justiz S, Kahn AD, De Decker S, Grapes NJ, Beasley M, Du J, Pancotto TE, Suñol A, Shinn R, DeCicco B, Burkland E, Cridge H. Van Hoof C, et al. J Vet Intern Med. 2023 Jun 8. doi: 10.1111/jvim.16785. Online ahead of print. J Vet Intern Med. 2023. PMID: 37288966
Breed distribution was compared to a control group. Agreement between imaging modalities was assessed via Cohen's kappa statistic. Other analyses were performed on categorical data, using cross tabulations with chi-squared and Fisher's exact tests. ...
Breed distribution was compared to a control group. Agreement between imaging modalities was assessed via Cohen's kappa statistic. Ot …
Profiling and predicting distinct tau progression patterns: An unsupervised data-driven approach to flortaucipir positron emission tomography.
Tosun D, Thropp P, Southekal S, Spottiswoode B, Fahmi R; Alzheimer's Disease Neuroimaging Initiative. Tosun D, et al. Alzheimers Dement. 2023 Jun 8. doi: 10.1002/alz.13164. Online ahead of print. Alzheimers Dement. 2023. PMID: 37288753
RESULTS: The data-driven analysis of longitudinal flortaucipir PET from studies done by the Alzheimer's Disease Neuroimaging Initiative, Avid Pharmaceuticals, and Harvard Aging Brain Study (N = 348 cognitively unimpaired, N = 188 mild cognitive impairment, N = 77 dementia) …
RESULTS: The data-driven analysis of longitudinal flortaucipir PET from studies done by the Alzheimer's Disease Neuroimaging Initiati …
A versatile laser-induced porcine model of outer retinal and choroidal degeneration for preclinical testing.
Barone F, Amaral J, Bunea I, Farnoodian M, Gupta R, Gupta R, Baker D, Phillips MJ, Blanch RJ, Maminishkis A, Gamm DM, Bharti K. Barone F, et al. JCI Insight. 2023 Jun 8;8(11):e157654. doi: 10.1172/jci.insight.157654. JCI Insight. 2023. PMID: 37288665
However, accelerated development of effective cell therapies is hampered by the lack of large-animal models that allow testing safety and efficacy of clinical doses covering the human macula (20 mm2). We developed a versatile pig model to mimic different types and stages o …
However, accelerated development of effective cell therapies is hampered by the lack of large-animal models that allow testing safety and ef …
Diagnostic methods to measure spastic segment and guide tailored myotomy length in type 3 achalasia.
Low EE, Hasan A, Fehmi SA, Chang MA, Kwong W, Krinsky ML, Anand G, Greytak M, Kaizer A, Yadlapati R. Low EE, et al. Neurogastroenterol Motil. 2023 Jun 8:e14625. doi: 10.1111/nmo.14625. Online ahead of print. Neurogastroenterol Motil. 2023. PMID: 37288617
Spastic segments were defined as HRM-distance between proximal borders of lower esophageal sphincter and high-pressure area (isobaric contour 70 mmHg); EUS-length of thickened circular muscle (1.2 mm) from proximal border of esophagogastric junction (EGJ) to the transition to a n …
Spastic segments were defined as HRM-distance between proximal borders of lower esophageal sphincter and high-pressure area (isobaric contou …
Computational fluid dynamics-based virtual angiograms for the detection of flow stagnation in intracranial aneurysms.
Hadad S, Karnam Y, Mut F, Lohner R, Robertson AM, Kaneko N, Cebral JR. Hadad S, et al. Int J Numer Method Biomed Eng. 2023 Jun 8:e3740. doi: 10.1002/cnm.3740. Online ahead of print. Int J Numer Method Biomed Eng. 2023. PMID: 37288602
Using a small sample of 14 IAs of which seven were previously classified as having flow stagnation, it was found that a threshold RET value of 0.46 s can successfully identify flow stagnation. CFD-based prediction of stagnation was in more than 90% agreement with independe …
Using a small sample of 14 IAs of which seven were previously classified as having flow stagnation, it was found that a threshold RET value …
Dynamic lung water MRI during exercise stress.
Seemann F, Javed A, Khan JM, Bruce CG, Chae R, Yildirim DK, Potersnak A, Wang H, Baute S, Ramasawmy R, Lederman RJ, Campbell-Washburn AE. Seemann F, et al. Magn Reson Med. 2023 Jun 8. doi: 10.1002/mrm.29716. Online ahead of print. Magn Reson Med. 2023. PMID: 37288601
Time-resolved images were acquired at 0.55T using a continuous 3D stack-of-spirals proton density weighted sequence with 3.5 mm isotropic resolution, and derived using a motion corrected sliding-window reconstruction with 90-s temporal resolution in 20-s increments. …
Time-resolved images were acquired at 0.55T using a continuous 3D stack-of-spirals proton density weighted sequence with 3.5 mm isotropic re …
Lung T2 * mapping using 3D ultrashort TE with tight intervals δTE.
Malis V, Kassai Y, Vucevic D, Bae WC, Ohno Y, Yen A, Miyazaki M. Malis V, et al. Magn Reson Med. 2023 Jun 8. doi: 10.1002/mrm.29756. Online ahead of print. Magn Reson Med. 2023. PMID: 37288577
In the phantom study, the T2* was measured up to three times more accurately compared with standard six-echo UTE. In human lungs, T2* maps were successfully obtained from 10 echoes, yielding average values T2* = 1.62 0.48 ms for mono-exponential and T2s* = 1.00 0.53 ms for …
In the phantom study, the T2* was measured up to three times more accurately compared with standard six-echo UTE. In human lungs, T2* …
An integrated finite element method and machine learning algorithm for brain morphology prediction.
Chavoshnejad P, Chen L, Yu X, Hou J, Filla N, Zhu D, Liu T, Li G, Razavi MJ, Wang X. Chavoshnejad P, et al. Cereb Cortex. 2023 Jun 7:bhad208. doi: 10.1093/cercor/bhad208. Online ahead of print. Cereb Cortex. 2023. PMID: 37288479
The human brain development experiences a complex evolving cortical folding from a smooth surface to a convoluted ensemble of folds. ...
The human brain development experiences a complex evolving cortical folding from a smooth surface to a convoluted ensemble of folds. …
Translation, cross-cultural adaptation and validation of the Persian version of selected PROMIS measures for use in lumbar canal stenosis patients.
Oskouie IM, Rostami M, Moosavi M, Zarei M, Jouibari MF, Ataie H, Jafarieh A, Moghadam N, Kordi R, Khadivi M, Mazloumi A. Oskouie IM, et al. J Educ Health Promot. 2023 Mar 31;12:99. doi: 10.4103/jehp.jehp_668_22. eCollection 2023. J Educ Health Promot. 2023. PMID: 37288413 Free PMC article.
BACKGROUND: The National Institutes of Health (NIH) developed a new measurement system called the Patient-Reported Outcomes Measurement Information System (PROMIS) which can be used for multiple health conditions. ...Construct validity of differ …
BACKGROUND: The National Institutes of Health (NIH) developed a new measurement system called the Patient-Report …
Description, Feasibility, and Histological Assessment of the Vsling, a Novel Transcatheter Ventricular Repair Device.
Stone GW, Sievert H, Virmani R, Shaler LW, Manash B, Neustadter D. Stone GW, et al. Struct Heart. 2022 Aug 1;6(4):100075. doi: 10.1016/j.shj.2022.100075. eCollection 2022 Aug. Struct Heart. 2022. PMID: 37288331 Free PMC article.
METHODS: The Vsling transcatheter papillary muscle sling device was evaluated in a chronic animal model (sacrificed at 30 and 90 days), in a simulator, and in a human cadaver. RESULTS: The Vsling device was successfully implanted in 10 pigs, 6 simulator procedures, and 1 …
METHODS: The Vsling transcatheter papillary muscle sling device was evaluated in a chronic animal model (sacrificed at 30 and 90 days), in a …
Levodopa responsive gait dynamics in OFF- and ONOFF-state freezing of gait in Parkinson's disease.
Virmani T, Pillai L, Glover A, Landes RD. Virmani T, et al. Clin Park Relat Disord. 2023 May 26;9:100202. doi: 10.1016/j.prdoa.2023.100202. eCollection 2023. Clin Park Relat Disord. 2023. PMID: 37288072 Free PMC article.
BACKGROUND: In people with Parkinson's disease (PwPD), Freezing of Gait (FOG) episodes can be levodopa responsive (OFF-FOG) or levodopa unresponsive (ONOFF-FOG). ...
BACKGROUND: In people with Parkinson's disease (PwPD), Freezing of Gait (FOG) episodes can be levodopa responsive (OFF-FOG) or levodo …
Anterior distal femoral hemiepiphysiodesis in children with cerebral palsy: Establishing surgical indications and techniques using the modified Delphi method and literature review.
Shore BJ, McCarthy J, Shrader MW, Graham K, Veerkamp KM, Rutz E, Chambers H, Davids JR, Narayanan U, Novacheck TF, Pierz K, Dreher T, Rhodes J, Shilt J, Theologis T, Van Campenhout A, Kay RM. Shore BJ, et al. J Child Orthop. 2023 Jun 1;17(3):292-294. doi: 10.1177/18632521231172993. eCollection 2023 Jun. J Child Orthop. 2023. PMID: 37288042 Free PMC article. No abstract available.
The Surgical Timing and Prognoses of Elderly Patients with Hip Fractures: A Retrospective Analysis.
Sun L, Wang C, Zhang M, Li X, Zhao B. Sun L, et al. Clin Interv Aging. 2023 Jun 2;18:891-899. doi: 10.2147/CIA.S408903. eCollection 2023. Clin Interv Aging. 2023. PMID: 37287528 Free PMC article.
There were no significant differences between the two groups in terms of mortality and excellent rates of the HHS at six months after the operation. In addition, the early surgery group had a lower readmission rate than the delayed surgery group [34 (9.5%) vs 56 (16.3%), P …
There were no significant differences between the two groups in terms of mortality and excellent rates of the HHS at six months after …
A call to address structural barriers to Hispanic/Latino representation in clinical trials on Alzheimer's disease and related dementias: A micro-meso-macro perspective.
Aranda MP, Marquez DX, Gallagher-Thompson D, Pérez A, Rojas JC, Hill CV, Reyes Y, Dilworth-Anderson P, Portacolonem E. Aranda MP, et al. Alzheimers Dement (N Y). 2023 Jun 5;9(2):e12389. doi: 10.1002/trc2.12389. eCollection 2023 Apr-Jun. Alzheimers Dement (N Y). 2023. PMID: 37287471 Free PMC article.
INTRODUCTION: This perspective paper addresses the US Hispanic/Latino (herein, Latino) experience with regards to a significant public health concern-the underrepresentation of Latino persons in Alzheimer's disease and related dementias (AD/ADRD) clinical trials. .. …
INTRODUCTION: This perspective paper addresses the US Hispanic/Latino (herein, Latino) experience with regards to a significant public he …
Barriers and facilitators to participating in Alzheimer's disease biomarker research in black and white older adults.
Eliacin J, Polsinelli AJ, Epperson F, Gao S, Van Heiden S, Westmoreland G, Richards R, Richards M, Campbell C, Hendrie H, Risacher SL, Saykin AJ, Wang S. Eliacin J, et al. Alzheimers Dement (N Y). 2023 Jun 5;9(2):e12399. doi: 10.1002/trc2.12399. eCollection 2023 Apr-Jun. Alzheimers Dement (N Y). 2023. PMID: 37287470 Free PMC article.
INTRODUCTION: The study examined Black and White prospective participants' views of barriers to and facilitators of participation in Alzheimer's disease (AD) biomarker research. METHODS: In a mixed-methods study, 399 community-dwelling Black and White older adults (age 55) …
INTRODUCTION: The study examined Black and White prospective participants' views of barriers to and facilitators of participation in Alzheim …
Valosin-containing protein (VCP/p97) is prognostically unfavorable in pediatric AML, and negatively correlates with unfolded protein response proteins IRE1 and GRP78: A report from the Children's Oncology Group.
Hoff FW, Qiu Y, Brown BD, Gerbing RB, Leonti AR, Ries RE, Gamis AS, Aplenc R, Kolb EA, Alonzo TA, Meshinchi S, Jenkins GN, Horton TM, Kornblau SM. Hoff FW, et al. Proteomics Clin Appl. 2023 Jun 7:e2200109. doi: 10.1002/prca.202200109. Online ahead of print. Proteomics Clin Appl. 2023. PMID: 37287368
EXPERIMENTAL DESIGN: Protein expression levels of valosin-containing protein (VCP), a chief element of ERAD, were measured in peripheral blood samples from in 483 pediatric AML patients using reverse phase protein array methodology. Patients participated in the Children's …
EXPERIMENTAL DESIGN: Protein expression levels of valosin-containing protein (VCP), a chief element of ERAD, were measured in peripheral blo …
Adequacy of Children's Psychopharmacology Services: Variations by Race and Clinical Characteristics.
Young AS, Findling RL, Riehm KE, Seegan P, Crum RM, Mojtabai R, Chiappini EA, Youngstrom EA, Fristad MA, Arnold LE, Birmaher B, Horwitz SM. Young AS, et al. Psychiatr Serv. 2023 Jun 8:appips20220375. doi: 10.1176/appi.ps.20220375. Online ahead of print. Psychiatr Serv. 2023. PMID: 37287230
OBJECTIVE: An expert consensus approach was used to determine the adequacy of children's psychopharmacology and to examine whether adequacy varied by demographic or clinical characteristics. ...Children and parents were interviewed with the Kiddie Schedule for Affective Di …
OBJECTIVE: An expert consensus approach was used to determine the adequacy of children's psychopharmacology and to examine whether ad …
An ERP measure of non-conscious memory reveals dissociable implicit processes in human recognition using an open-source automated analytic pipeline.
Addante RJ, Lopez-Calderon J, Allen N, Luck C, Muller A, Sirianni L, Inman CS, Drane DL. Addante RJ, et al. Psychophysiology. 2023 Jun 7:e14334. doi: 10.1111/psyp.14334. Online ahead of print. Psychophysiology. 2023. PMID: 37287106
Non-conscious processing of human memory has traditionally been difficult to objectively measure and thus understand. ...Results suggest first that equating for reported awareness of memory strength is a valid, powerful new method for revealing neural correlates of non-con …
Non-conscious processing of human memory has traditionally been difficult to objectively measure and thus understand. ...Results sugg …
The POP (Permanent Supportive Housing Overdose Prevention) Study: protocol for a hybrid type 3 stepped-wedge cluster randomized controlled trial.
Doran KM, Torsiglieri A, Blaufarb S, Hernandez P, Melnick E, Velez L, Cleland CM, Neighbors C, O'Grady MA, Shelley D. Doran KM, et al. Implement Sci. 2023 Jun 7;18(1):21. doi: 10.1186/s13012-023-01278-z. Implement Sci. 2023. PMID: 37287026
BACKGROUND: Permanent supportive housing (PSH)-subsidized housing paired with support services such as case management-is a key part of national strategic plans to end homelessness. ...The trial will include 20 PSH buildings (with building size ranging from 20 to ov …
BACKGROUND: Permanent supportive housing (PSH)-subsidized housing paired with support services such as case management-is a key part …
Akkermansia muciniphila and its membrane protein ameliorates intestinal inflammatory stress and promotes epithelial wound healing via CREBH and miR-143/145.
Wade H, Pan K, Duan Q, Kaluzny S, Pandey E, Fatumoju L, Saraswathi V, Wu R, Harris EN, Su Q. Wade H, et al. J Biomed Sci. 2023 Jun 7;30(1):38. doi: 10.1186/s12929-023-00935-1. J Biomed Sci. 2023. PMID: 37287024
Moreover, the gene expressing an outer membrane protein of A. muciniphila, Amuc_1100, was cloned into a mammalian cell-expression vector and successfully expressed in porcine and human IECs. Expression of Amuc_1100 in IECs could recapitulate the health beneficial ef …
Moreover, the gene expressing an outer membrane protein of A. muciniphila, Amuc_1100, was cloned into a mammalian cell-expression vector and …
Evaluating the mouse neural precursor line, SN4741, as a suitable proxy for midbrain dopaminergic neurons.
Boyd RJ, McClymont SA, Barrientos NB, Hook PW, Law WD, Rose RJ, Waite EL, Rathinavelu J, Avramopoulos D, McCallion AS. Boyd RJ, et al. BMC Genomics. 2023 Jun 7;24(1):306. doi: 10.1186/s12864-023-09398-y. BMC Genomics. 2023. PMID: 37286935
To overcome the ethical and technical limitations of in vivo human disease models, the broader scientific community frequently employs model organism-derived cell lines to investigate disease mechanisms, pathways, and therapeutic strategies. ...One such cellular surrogate …
To overcome the ethical and technical limitations of in vivo human disease models, the broader scientific community frequently employ …
A preliminary examination of sexual and physical victimization 6 months after recent rape.
Walsh K, Gilmore AK, Jaffe AE, Frazier P, Ledray L, Acierno R, Ruggiero KJ, Kilpatrick DG, Resnick HS. Walsh K, et al. Arch Womens Ment Health. 2023 Jun 8. doi: 10.1007/s00737-023-01335-y. Online ahead of print. Arch Womens Ment Health. 2023. PMID: 37286883
Multiple experiences of sexual and physical violence are associated with elevated mental and physical health problems. This secondary analysis examined the prevalence and correlates of experiencing sexual or physical violence within 6 months of a sexual assault medical for …
Multiple experiences of sexual and physical violence are associated with elevated mental and physical health problems. This secondary …
Understanding the Predictors of Low Take-Up of the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC): A Nationwide Longitudinal Study.
Guan A, Batra A, Seligman H, Hamad R. Guan A, et al. Matern Child Health J. 2023 Jun 7. doi: 10.1007/s10995-023-03728-y. Online ahead of print. Matern Child Health J. 2023. PMID: 37286848
INTRODUCTION: The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is among the largest U.S. social safety net programs. Although strong evidence exists regarding the benefits of WIC, take-up (i.e., participation among eligible individua …
INTRODUCTION: The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is among the largest U.S. soci …
Expressive language sampling and outcome measures for treatment trials in fragile X and down syndromes: composite scores and psychometric properties.
Abbeduto L, Del Hoyo Soriano L, Berry-Kravis E, Sterling A, Edgin JO, Abdelnur N, Drayton A, Hoffmann A, Hamilton D, Harvey DJ, Thurman AJ. Abbeduto L, et al. Sci Rep. 2023 Jun 7;13(1):9267. doi: 10.1038/s41598-023-36087-3. Sci Rep. 2023. PMID: 37286643
Research on Expressive Language Sampling (ELS) procedures suggest it is a promising approach to measuring treatment efficacy. ELS entails collecting samples of a participant's talk in interactions with an examiner that are naturalistic but sufficiently structured to ensure …
Research on Expressive Language Sampling (ELS) procedures suggest it is a promising approach to measuring treatment efficacy. ELS entails co …
Large scale proteomic studies create novel privacy considerations.
Hill AC, Guo C, Litkowski EM, Manichaikul AW, Yu B, Konigsberg IR, Gorbet BA, Lange LA, Pratte KA, Kechris KJ, DeCamp M, Coors M, Ortega VE, Rich SS, Rotter JI, Gerzsten RE, Clish CB, Curtis JL, Hu X, Obeidat ME, Morris M, Loureiro J, Ngo D, O'Neal WK, Meyers DA, Bleecker ER, Hobbs BD, Cho MH, Banaei-Kashani F, Bowler RP. Hill AC, et al. Sci Rep. 2023 Jun 7;13(1):9254. doi: 10.1038/s41598-023-34866-6. Sci Rep. 2023. PMID: 37286633
Stabilization of pre-existing neurotensin receptor conformational states by β-arrestin-1 and the biased allosteric modulator ML314.
Bumbak F, Bower JB, Zemmer SC, Inoue A, Pons M, Paniagua JC, Yan F, Ford J, Wu H, Robson SA, Bathgate RAD, Scott DJ, Gooley PR, Ziarek JJ. Bumbak F, et al. Nat Commun. 2023 Jun 7;14(1):3328. doi: 10.1038/s41467-023-38894-8. Nat Commun. 2023. PMID: 37286565
We used (13)C(epsilon)H(3)-methionine NMR spectroscopy to show that binding of phosphatidylinositol-4,5-bisphosphate (PIP2) to the receptor's intracellular surface allosterically tunes the timescale of motions at the orthosteric pocket and conserved activation motifs - wit …
We used (13)C(epsilon)H(3)-methionine NMR spectroscopy to show that binding of phosphatidylinositol-4,5-bisphosphate (PIP2) to the receptor' …
Integrated multi-omics analyses reveal homology-directed repair pathway as a unique dependency in near-haploid leukemia.
Liu-Lupo Y, Ham JD, Jeewajee SKA, Nguyen L, Delorey T, Ramos A, Weinstock DM, Regev A, Hemann MT. Liu-Lupo Y, et al. Blood Cancer J. 2023 Jun 8;13(1):92. doi: 10.1038/s41408-023-00863-1. Blood Cancer J. 2023. PMID: 37286545
DNA damage analyses revealed significantly increased sensitivity of RAD51-mediated repair to RAD51B loss in the G2/M stage of near-haploid cells, suggesting a unique role of RAD51B in the homologous recombination pathway. Elevated G2/M and G1/S checkpoint signaling was par …
DNA damage analyses revealed significantly increased sensitivity of RAD51-mediated repair to RAD51B loss in the G2/M stage of near-haploid c …
PEOPLE (NTC03447678), a phase II trial to test pembrolizumab as first-line treatment in patients with advanced NSCLC with PD-L1 <50%: a multiomics analysis.
Lo Russo G, Prelaj A, Dolezal J, Beninato T, Agnelli L, Triulzi T, Fabbri A, Lorenzini D, Ferrara R, Brambilla M, Occhipinti M, Mazzeo L, Provenzano L, Spagnoletti A, Viscardi G, Sgambelluri F, Brich S, Miskovic V, Pedrocchi ALG, Trovo' F, Manglaviti S, Giani C, Ambrosini P, Leporati R, Franza A, McCulloch J, Torelli T, Anichini A, Mortarini R, Trinchieri G, Pruneri G, Torri V, De Braud F, Proto C, Ganzinelli M, Garassino MC. Lo Russo G, et al. J Immunother Cancer. 2023 Jun;11(6):e006833. doi: 10.1136/jitc-2023-006833. J Immunother Cancer. 2023. PMID: 37286305 Free article.
Effect of 2022 ACC/AHA/HFSA Criteria on Stages of Heart Failure in a Pooled Community Cohort.
Mohebi R, Wang D, Lau ES, Parekh JK, Allen N, Psaty BM, Benjamin EJ, Levy D, Wang TJ, Shah SJ, Gottdiener JS, Januzzi JL Jr, Ho JE. Mohebi R, et al. J Am Coll Cardiol. 2023 Jun 13;81(23):2231-2242. doi: 10.1016/j.jacc.2023.04.007. J Am Coll Cardiol. 2023. PMID: 37286252
METHODS: Study participants from 3 longitudinal cohorts (the MESA [Multi-Ethnic Study of Atherosclerosis], CHS [Cardiovascular Health Study], and the FHS [Framingham Heart Study]), were categorized into 4 HF stages according to the 2013 and 2022 criteria. ...
METHODS: Study participants from 3 longitudinal cohorts (the MESA [Multi-Ethnic Study of Atherosclerosis], CHS [Cardiovascular Health …
A refresh of the top 10 research priorities in cystic fibrosis.
Rowbotham NJ, Smith S, Elliott ZC, Cupid B, Allen LJ, Cowan K, Allen L, Smyth AR. Rowbotham NJ, et al. Thorax. 2023 Jun 7:thorax-2023-220100. doi: 10.1136/thorax-2023-220100. Online ahead of print. Thorax. 2023. PMID: 37286236
Use of nonstigmatizing language is associated with improved outcomes in hospitalized people who inject drugs.
Carpenter JE, Catalanotti J, Notis M, Brokus C, Moran TP, Akselrod H, Burkholder G, Eaton EF, Kuo I, Mai W, McGonigle K, Steck A, Del Rio C, Saag M, Kottilil S, Masur H, Kattakuzhy S, Rosenthal ES. Carpenter JE, et al. J Hosp Med. 2023 Jun 7. doi: 10.1002/jhm.13146. Online ahead of print. J Hosp Med. 2023. PMID: 37286190
DESIGNS: We performed a retrospective medical record review. SETTINGS AND PARTICIPANTS: Four U.S. academic health systems. Participants were patients with OUD admitted for infectious complications of injection opioid use from January 1, 2018, to December 31, …
DESIGNS: We performed a retrospective medical record review. SETTINGS AND PARTICIPANTS: Four U.S. academic health syste …
Trends in ingredients added to infant formula: FDA's experiences in the GRAS notification program.
Morissette R, Mihalov J, Carlson SJ, Kaneko KJ. Morissette R, et al. Food Chem Toxicol. 2023 Jun 5:113876. doi: 10.1016/j.fct.2023.113876. Online ahead of print. Food Chem Toxicol. 2023. PMID: 37286029
In the United States, the Food and Drug Administration (FDA) establishes the requirements necessary to demonstrate the safety of infant formula within the framework of the Federal Food, Drug, and Cosmetic Act. FDA's Center for Food Safety and Applied Nutritio …
In the United States, the Food and Drug Administration (FDA) establishes the requirements necessary to demonstrate the safety …
Toxicity of repeated oral intake of organic selenium, inorganic selenium, and selenium nanoparticles: A review.
Hadrup N, Ravn-Haren G. Hadrup N, et al. J Trace Elem Med Biol. 2023 Jun 2;79:127235. doi: 10.1016/j.jtemb.2023.127235. Online ahead of print. J Trace Elem Med Biol. 2023. PMID: 37285631 Review.
Clinical signs of selenium toxicity in humans include a garlicky-smelling breath, hair loss, and nail changes. One human study showed increased mortality following daily ingestion of 300 g Se per day for 5 years, equal to a lowest-observed-adverse-effect level (LOAEL) of 4 …
Clinical signs of selenium toxicity in humans include a garlicky-smelling breath, hair loss, and nail changes. One human study showed …
Immune-Related Adverse Events and Clinical Outcomes in Advanced Urothelial Cancer Patients Treated With Immune Checkpoint Inhibitors.
Sanda GE, Shabto JM, Goyal S, Liu Y, Martini DJ, Nazha B, Brown JT, Yantorni LB, Russler GA, Caulfield S, Joshi SS, Narayan VM, Kissick H, Ogan K, Master VA, Carthon BC, Kucuk O, Bilen MA. Sanda GE, et al. Oncologist. 2023 Jun 7:oyad154. doi: 10.1093/oncolo/oyad154. Online ahead of print. Oncologist. 2023. PMID: 37285524
MATERIALS AND METHODS: In this retrospective study, we investigated 70 patients with advanced UC treated with ICIs at Winship Cancer Institute from 2015 to 2020. Data on patients were collected through chart review. Cox's proportional hazard model and logistic regression w …
MATERIALS AND METHODS: In this retrospective study, we investigated 70 patients with advanced UC treated with ICIs at Winship Cancer Institu …
Home Care in America: The Urgent Challenge of Putting Ethical Care into Practice.
Solis C, Mintz KT, Wasserman D, Fenton K, Danis M. Solis C, et al. Hastings Cent Rep. 2023 May;53(3):25-34. doi: 10.1002/hast.1487. Hastings Cent Rep. 2023. PMID: 37285413
Home care is one of the fastest-growing industries in the United States, providing valuable opportunities for millions of older adults and people with disabilities to live at home rather than in institutional settings. ...
Home care is one of the fastest-growing industries in the United States, providing valuable opportunities for millions of olde …
Influenza and Influenza-Like Virus Infection in Children Under 14 Years of Age: An Investigation of 725 Cases in the 2021/2022 Influenza Epidemic Season in Poland.
Kondratiuk K, Hallmann E, Łuniewska K, Szymański K, Brydak L. Kondratiuk K, et al. Med Sci Monit. 2023 Jun 7;29:e940368. doi: 10.12659/MSM.940368. Med Sci Monit. 2023. PMID: 37285325
MATERIAL AND METHODS The material for the study (nose and throat swabs) was collected during the 2021/2022 epidemic season. We analyzed 725 samples from the National Influenza Center, Department of Influenza Research at the National Institute of Public Health …
MATERIAL AND METHODS The material for the study (nose and throat swabs) was collected during the 2021/2022 epidemic season. We analyzed 725 …
MCR toolkit: A GPU-based toolkit for multi-channel reconstruction of preclinical and clinical x-ray CT data.
Clark DP, Badea CT. Clark DP, et al. Med Phys. 2023 Jun 7. doi: 10.1002/mp.16532. Online ahead of print. Med Phys. 2023. PMID: 37285215
METHODS: The MCR Toolkit source code is implemented in C/C++ and NVIDIA's CUDA GPU programming interface, with scripting support from MATLAB and Python. ...A fixed set of projection data is used across all reconstruction cases to demonstrate the Toolkit's robustness …
METHODS: The MCR Toolkit source code is implemented in C/C++ and NVIDIA's CUDA GPU programming interface, with scripting support from …
Eliminating children's tobacco smoke exposure: a pathway to bioverified abstinence among low-income maternal smokers in the Babies Living Safe and Smokefree (BLiSS) trial.
Collins BN, Lepore SJ, Egleston BL. Collins BN, et al. J Behav Med. 2023 Jun 7. doi: 10.1007/s10865-023-00423-9. Online ahead of print. J Behav Med. 2023. PMID: 37285107
Random effects regression analysis tested mediation. RESULTS: Elimination of children's tobacco smoke exposure (TSE) at Time 2 was the only significant mediator of longitudinal smoking abstinence through Time 3. AAR + MBI mothers were more likely to eliminate their childre …
Random effects regression analysis tested mediation. RESULTS: Elimination of children's tobacco smoke exposure (TSE) at Time 2 was th …
What Do We Know About Depression Among Youth and How Can We Make Progress Toward Improved Understanding and Reducing Distress? A New Hope.
Hankin BL, Griffith JM. Hankin BL, et al. Clin Child Fam Psychol Rev. 2023 Jun 7. doi: 10.1007/s10567-023-00437-4. Online ahead of print. Clin Child Fam Psychol Rev. 2023. PMID: 37285011 Review.
At the same time, the field appears stuck and has not achieved considerable progress in advancing scientific understanding of depression's features or delivering interventions to meet the challenge of youth depression's high and growing prevalence. ...First, we emph …
At the same time, the field appears stuck and has not achieved considerable progress in advancing scientific understanding of depression' …
Innovative Approaches to Improve COVID-19 Case Investigation and Contact Tracing Among Refugees, Immigrants, and Migrants: Lessons Learned from a Newly Established National Resource Center.
Mann EM, Weinberg M, Dawson-Hahn E, Clarke SK, Olmsted M, Bertelsen N, Arun R, Keaveney M, Miko S, Kircher A, Pendleton AE, Hendel-Paterson B, Prasad S, Stauffer WM. Mann EM, et al. J Immigr Minor Health. 2023 Jun 7. doi: 10.1007/s10903-023-01508-y. Online ahead of print. J Immigr Minor Health. 2023. PMID: 37284967
Effective COVID-19 case investigation and contact tracing (CICT) among refugee, immigrant, and migrant (RIM) communities requires innovative approaches to address linguistic, cultural and community specific preferences. The National Resource Center for Refugees, Immigrants …
Effective COVID-19 case investigation and contact tracing (CICT) among refugee, immigrant, and migrant (RIM) communities requires innovative …
Fear of COVID and Physical Health Among People Living with HIV in China: Mediation Effects of HIV Stigma, Social Support, and Substance Use.
Chen WT, Huang F, Sun W, Zhang L. Chen WT, et al. AIDS Behav. 2023 Jun 7. doi: 10.1007/s10461-023-04099-9. Online ahead of print. AIDS Behav. 2023. PMID: 37284924
The COVID-19 pandemic has uniquely impacted people living with HIV (PLWH) worldwide. The negative impacts on PLWH's mental health from fear of COVID-19 are labeled as "a double stress." ...This is one of the first studies to explore how fear of contracting COVID-19 …
The COVID-19 pandemic has uniquely impacted people living with HIV (PLWH) worldwide. The negative impacts on PLWH's mental health …
The Impact of Climate Change on Asthma and Allergic-Immunologic Disease.
Kelly G, Idubor OI, Binney S, Schramm PJ, Mirabelli MC, Hsu J. Kelly G, et al. Curr Allergy Asthma Rep. 2023 Jun 7. doi: 10.1007/s11882-023-01093-y. Online ahead of print. Curr Allergy Asthma Rep. 2023. PMID: 37284923 Review.
Climate change disproportionately affects some communities, which can exacerbate disparities in climate-sensitive diseases like asthma. Public health efforts include implementing a national strategic framework to help communities track, prevent, and respond to clima …
Climate change disproportionately affects some communities, which can exacerbate disparities in climate-sensitive diseases like asthma. Publ …
The Role of Peer- and Self-Appraisals in the Association Between Maltreatment and Symptomatology.
Ross AJ, Ha ED, Toth SL, Manly JT, Cicchett D. Ross AJ, et al. Res Child Adolesc Psychopathol. 2023 Jun 7. doi: 10.1007/s10802-023-01083-8. Online ahead of print. Res Child Adolesc Psychopathol. 2023. PMID: 37284898
The current study utilizes structural equation modeling to examine the impact of an adapted threat versus deprivation framework for conceptualizing maltreatment via children's negative conceptions of relationships, which have not been previously tested as mechanisms in the …
The current study utilizes structural equation modeling to examine the impact of an adapted threat versus deprivation framework for conceptu …
Consequences of microsporidian prior exposure for virus infection outcomes and bumble bee host health.
McCormick EC, Cohen OR, Dolezal AG, Sadd BM. McCormick EC, et al. Oecologia. 2023 Jun 7. doi: 10.1007/s00442-023-05394-x. Online ahead of print. Oecologia. 2023. PMID: 37284861
Host-parasite interactions do not occur in a vacuum, but in connected multi-parasite networks that can result in co-exposures and coinfections of individual hosts. These can affect host health and disease ecology, including disease outbreaks. However, many host-parasite st …
Host-parasite interactions do not occur in a vacuum, but in connected multi-parasite networks that can result in co-exposures and coinfectio …
Olanzapine With or Without Fosaprepitant for Preventing Chemotherapy Induced Nausea and Vomiting in Patients Receiving Highly Emetogenic Chemotherapy: A Phase III Randomized, Double-Blind, Placebo-Controlled Trial (ALLIANCE A221602).
Navari RM, Le-Rademacher J, Smieliauskas F, Ruddy KJ, James Saphner T, Liu H, Harlos E, Onitilo AA, Giridhar K, Paul Singh P, Reddy PS, Chow S, Kruter F, Raptis G, Loprinzi CL. Navari RM, et al. Oncologist. 2023 Jun 7:oyad140. doi: 10.1093/oncolo/oyad140. Online ahead of print. Oncologist. 2023. PMID: 37284847
Neural circuit-wide analysis of changes to gene expression during deafening-induced birdsong destabilization.
Colquitt BM, Li K, Green F, Veline R, Brainard MS. Colquitt BM, et al. Elife. 2023 Jun 7;12:e85970. doi: 10.7554/eLife.85970. Elife. 2023. PMID: 37284822
We also found that connected song regions exhibit correlations in gene expression that were reduced in deafened birds relative to hearing birds, suggesting that song destabilization alters the inter-region coordination of transcriptional states. Finally, lesioning LMAN, a …
We also found that connected song regions exhibit correlations in gene expression that were reduced in deafened birds relative to hearing bi …
Combined lineage tracing and scRNA-seq reveals unexpected first heart field predominance of human iPSC differentiation.
Galdos FX, Lee C, Lee S, Paige S, Goodyer W, Xu S, Samad T, Escobar GV, Darsha A, Beck A, Bak RO, Porteus MH, Wu S. Galdos FX, et al. Elife. 2023 Jun 7;12:e80075. doi: 10.7554/eLife.80075. Online ahead of print. Elife. 2023. PMID: 37284748
While these populations have been extensively studied in non-human model systems, their identification and study in vivo human tissues have been limited due to the ethical and technical limitations of accessing gastrulation stage human embryos. Human i …
While these populations have been extensively studied in non-human model systems, their identification and study in vivo human …
The impact of task context on predicting finger movements in a brain-machine interface.
Mender MJ, Nason-Tomaszewski SR, Temmar H, Costello JT, Wallace DM, Willsey MS, Ganesh Kumar N, Kung TA, Patil P, Chestek CA. Mender MJ, et al. Elife. 2023 Jun 7;12:e82598. doi: 10.7554/eLife.82598. Online ahead of print. Elife. 2023. PMID: 37284744
With functional electrical stimulation (FES) for example, the patient's own hand will be used to produce a wide range of forces in otherwise similar movements. ...However, with respect to online BMI control of the virtual hand, changing either the decoder training task con …
With functional electrical stimulation (FES) for example, the patient's own hand will be used to produce a wide range of forces in ot …
NanoSpot™ collector for aerosol sample collection for direct microscopy and spectroscopy analysis.
Zervaki O, Stump B, Keady P, Dionysiou DD, Kulkarni P. Zervaki O, et al. Aerosol Sci Technol. 2023 Jan;57(4):342-354. doi: 10.1080/02786826.2023.2167648. Aerosol Sci Technol. 2023. PMID: 37284690 Free PMC article.
A spot deposit of approximately 0.7-mm diameter is formed for particles over a broad particle diameter range, for effective coupling with microscopic and spectroscopic analysis. Finally, the NanoSpot() collector's analytical measurement sensitivity for laser Raman analysis …
A spot deposit of approximately 0.7-mm diameter is formed for particles over a broad particle diameter range, for effective coupling with mi …
Bayesian Multistate Life Table Methods for Large and Complex State Spaces: Development and Illustration of a New Method.
Lynch SM, Zang E. Lynch SM, et al. Sociol Methodol. 2022 Aug;52(2):254-286. doi: 10.1177/00811750221112398. Epub 2022 Jul 23. Sociol Methodol. 2022. PMID: 37284595
However, the approach is limited to estimating years to be spent in only two living states, such as "healthy" and "unhealthy." In this article, the authors extend this method to allow for large state spaces with "quasi-absorbing" states. The authors illustrate the n …
However, the approach is limited to estimating years to be spent in only two living states, such as "healthy" and "unhealthy." In thi …
Use of Population-Level Administrative Data in Developmental Science.
Milne BJ, D'Souza S, Andersen SH, Richmond-Rakerd LS. Milne BJ, et al. Annu Rev Dev Psychol. 2022 Dec;4(1):447-468. doi: 10.1146/annurev-devpsych-120920-023709. Epub 2022 Sep 14. Annu Rev Dev Psychol. 2022. PMID: 37284522
Population-level administrative data-data on individuals' interactions with administrative systems (e.g., health, criminal justice, and education)-have substantially advanced our understanding of life-course development. ...Further advances will be made by linking prospect …
Population-level administrative data-data on individuals' interactions with administrative systems (e.g., health, criminal justice, a …
Measuring Ethnic Diversity.
Steele LG, Bostic A, Lynch SM, Abdelaaty L. Steele LG, et al. Annu Rev Sociol. 2022 Jul;48(1):43-63. doi: 10.1146/annurev-soc-030420-015435. Epub 2022 Apr 19. Annu Rev Sociol. 2022. PMID: 37284507
Reproducibility in the Social Sciences.
Moody JW, Keister LA, Ramos MC. Moody JW, et al. Annu Rev Sociol. 2022 Jul;48(1):65-85. doi: 10.1146/annurev-soc-090221-035954. Epub 2022 Apr 26. Annu Rev Sociol. 2022. PMID: 37284506
Nonprofit Financial Response to Immigration.
Le Barbenchon C, Keister LA. Le Barbenchon C, et al. Nonprofit Volunt Sect Q. 2022 Dec;51(6):1399-1422. doi: 10.1177/08997640211057433. Epub 2021 Dec 22. Nonprofit Volunt Sect Q. 2022. PMID: 37284414
Nonprofit organizations are important actors in local communities, providing services to vulnerable populations and acting as stewards for charitable contributions from other members of the population. ...Because immigrant populations both receive and contribute to nonprof …
Nonprofit organizations are important actors in local communities, providing services to vulnerable populations and acting as steward …
Advice from local/site evaluators: How to manage "up" within a large-scale initiative.
Hwalek M, Honoré M, Brown S. Hwalek M, et al. New Dir Eval. 2022 Summer;2022(174):79-95. doi: 10.1002/ev.20504. Epub 2022 Aug 8. New Dir Eval. 2022. PMID: 37284175 Free PMC article.
BUilding Infrastructure Leading to Diversity (BUILD), an initiative of the National Institutes of Health (NIH), provides grants to undergraduate institutions to implement and study innovative approaches to engaging and retaining students from diverse b …
BUilding Infrastructure Leading to Diversity (BUILD), an initiative of the National Institutes of Health (NIH), …
DYNAMIC RISK PREDICTION TRIGGERED BY INTERMEDIATE EVENTS USING SURVIVAL TREE ENSEMBLES.
Sun Y, Chiou SH, Wu CO, McGarry M, Huang CY. Sun Y, et al. Ann Appl Stat. 2023 Jun;17(2):1375-1397. doi: 10.1214/22-aoas1674. Epub 2023 May 1. Ann Appl Stat. 2023. PMID: 37284167 Free PMC article.
With the availability of massive amounts of data from electronic health records and registry databases, incorporating time-varying patient information to improve risk prediction has attracted great attention. ...
With the availability of massive amounts of data from electronic health records and registry databases, incorporating time-varying pa …
Trauma Symptoms and Deliberate Self-Harm Among Sexual Violence Survivors: Examining State Emotion Regulation and Reactivity as Dual Mechanisms.
Brockdorf AN, Gratz KL, Messman TL, DiLillo D. Brockdorf AN, et al. Psychol Violence. 2023 Jan;13(1):23-33. doi: 10.1037/vio0000432. Epub 2022 May 23. Psychol Violence. 2023. PMID: 37284068
Because a common function of deliberate self-harm is to reduce negative internal states, SV survivors may use self-harm to cope with impairments in broader affective processes associated with PTSD symptoms. ...
Because a common function of deliberate self-harm is to reduce negative internal states, SV survivors may use self-harm to cope with …
Artificial Intelligence and Glaucoma: Going Back to Basics.
AlRyalat SA, Singh P, Kalpathy-Cramer J, Kahook MY. AlRyalat SA, et al. Clin Ophthalmol. 2023 May 31;17:1525-1530. doi: 10.2147/OPTH.S410905. eCollection 2023. Clin Ophthalmol. 2023. PMID: 37284059 Free PMC article. Review.
PET Image Denoising using a Deep-Learning Method for Extremely Obese Patients.
Liu H, Yousefi H, Mirian N, Lin M, Menard D, Gregory M, Aboian M, Boustani A, Chen MK, Saperstein L, Pucar D, Kulon M, Liu C. Liu H, et al. IEEE Trans Radiat Plasma Med Sci. 2022 Sep;6(7):766-770. doi: 10.1109/trpms.2021.3131999. Epub 2021 Dec 2. IEEE Trans Radiat Plasma Med Sci. 2022. PMID: 37284026
A deep learning-based noise reduction method with a fully 3D patch-based U-Net was used. Two U-Nets, U-Nets A and B, were trained on datasets with 40% and 10% count levels derived from 100 lean subjects, respectively. ...U-Net A effectively reduced the …
A deep learning-based noise reduction method with a fully 3D patch-based U-Net was used. Two U-Nets, U-Nets A and B, we …
Trends in HIV incidence following scale-up of harm reduction interventions among people who inject drugs in Kachin, Myanmar, 2008-2020: analysis of a retrospective cohort dataset.
McNaughton AL, Stone J, Oo KT, Let ZZ, Taw M, Aung MT, Min AM, Lim AG, Wisse E, Vickerman P. McNaughton AL, et al. Lancet Reg Health West Pac. 2023 Feb 27;34:100718. doi: 10.1016/j.lanwpc.2023.100718. eCollection 2023 May. Lancet Reg Health West Pac. 2023. PMID: 37283982 Free PMC article.
INTERPRETATION: Although HIV incidence is high among PWID in Kachin, data suggests it has decreased since the scale-up in harm reduction interventions. FUNDING: US NIH, Medecins du Monde....
INTERPRETATION: Although HIV incidence is high among PWID in Kachin, data suggests it has decreased since the scale-up in harm reduction int …
"What will people say?": Mental Health Stigmatization as a Barrier to Eating Disorder Treatment-Seeking for South Asian American Women.
Goel NJ, Thomas B, Boutté RL, Kaur B, Mazzeo SE. Goel NJ, et al. Asian Am J Psychol. 2023 Mar;14(1):96-113. doi: 10.1037/aap0000271. Epub 2022 Jan 10. Asian Am J Psychol. 2023. PMID: 37283957
Seven focus groups were conducted with 54 participants (M(age)=20.11 years, SD=2.52), all of whom had lived in the United States (US) for at least three years (63.0% of the sample was born in the US). ...Barriers to ED-treatment seeking were inextricable from barrie …
Seven focus groups were conducted with 54 participants (M(age)=20.11 years, SD=2.52), all of whom had lived in the United States …
A Socio-Ecological Model for Collegiate Recovery Programs.
Vest N, Hennessy E, Castedo de Martell S, Smith R. Vest N, et al. Addict Res Theory. 2023;31(2):92-99. doi: 10.1080/16066359.2022.2123471. Epub 2022 Sep 20. Addict Res Theory. 2023. PMID: 37283915
Given the major public health issue of substance use in the college environment and among college students, we must improve our understanding of students attempting to resolve substance related issues. ...To ground CRPs as an environmental support targeting emerging adults …
Given the major public health issue of substance use in the college environment and among college students, we must improve our under …
Effects of Ni precursors on the formation of Mg-Fe-Ni intermetallic hydrides, kinetics, and reversibility.
Dansirima P, Thiangviriya S, Plerdsranoy P, Chanlek N, Utke R. Dansirima P, et al. RSC Adv. 2023 Jun 5;13(25):16926-16934. doi: 10.1039/d3ra01914d. eCollection 2023 Jun 5. RSC Adv. 2023. PMID: 37283864 Free PMC article.
This work focuses on the effects of Ni precursors (metallic Ni or Mg(2)NiH(4)) on the formation of Mg-Fe-Ni intermetallic hydrides as well as their de/rehydrogenation kinetics and reversibility. After ball milling and sintering, the formation of Mg(2)FeH(6) and Mg(2)NiH …
This work focuses on the effects of Ni precursors (metallic Ni or Mg(2)NiH(4)) on the formation of Mg-Fe-Ni intermetallic hydrides as …
Preparation and applications of artificial mucins in biomedicine.
Detwiler RE, Kramer JR. Detwiler RE, et al. Curr Opin Solid State Mater Sci. 2022 Dec;26(6):101031. doi: 10.1016/j.cossms.2022.101031. Epub 2022 Sep 26. Curr Opin Solid State Mater Sci. 2022. PMID: 37283850 Free PMC article.
Mucin glycoproteins are the primary component of mucus and the epithelial glycocalyx. Aberrant mucin production is implicated in diverse disease states from cancer and inflammation to pre-term birth and infection. ...
Mucin glycoproteins are the primary component of mucus and the epithelial glycocalyx. Aberrant mucin production is implicated in diverse dis …
Changes in Mental Health and Well-Being Are Associated With Living Arrangements With Parents During COVID-19 Among Sexual Minority Young Persons in the U.S.
Salerno JP, Doan L, Sayer LC, Drotning KJ, Rinderknecht RG, Fish JN. Salerno JP, et al. Psychol Sex Orientat Gend Divers. 2023 Mar;10(1):150-156. doi: 10.1037/sgd0000520. Epub 2021 Sep 13. Psychol Sex Orientat Gend Divers. 2023. PMID: 37283818
Sexual minority young persons may be at risk for compounding mental health effects of the COVID-19 pandemic due to their existing vulnerabilities for psychological inequities. ...Patterns were not consistent among non-SMYAs, and lower magnitudes of change were seen. There …
Sexual minority young persons may be at risk for compounding mental health effects of the COVID-19 pandemic due to their existing vul …
Mechanisms for Hiding Sensitive Genotypes with Information-Theoretic Privacy.
Ye F, Cho H, Rouayheb SE. Ye F, et al. IEEE Trans Inf Theory. 2022 Jun;68(6):4090-4105. doi: 10.1109/tit.2022.3156276. Epub 2022 Mar 3. IEEE Trans Inf Theory. 2022. PMID: 37283781 Free PMC article.
Motivated by the growing availability of personal genomics services, we study an information-theoretic privacy problem that arises when sharing genomic data: a user wants to share his or her genome sequence while keeping the genotypes at certain positions hidden, which cou …
Motivated by the growing availability of personal genomics services, we study an information-theoretic privacy problem that arises wh …
Flexible method for generating needle-shaped beams and its application in optical coherence tomography.
Zhao J, Winetraub Y, DU L, VAN Vleck A, Ichimura K, Huang C, AAsI SZ, Sarin KY, DE LA Zerda A. Zhao J, et al. Optica. 2022 Aug 20;9(8):859-867. doi: 10.1364/optica.456894. Epub 2022 Jul 22. Optica. 2022. PMID: 37283722 Free PMC article.
NBs designed via this method successfully extended the DOF of our optical coherence tomography (OCT) system. It revealed clear individual epidermal cells of the entire human epidermis, fine structures of human dermal-epidermal junction in a large depth range, and a …
NBs designed via this method successfully extended the DOF of our optical coherence tomography (OCT) system. It revealed clear individual ep …
Mechanisms and treatment outcomes of ostial right coronary artery in-stent restenosis.
Yamamoto K, Sato T, Salem H, Matsumura M, Fall KN, Prasad M, Ng VG, Sethi SS, Nazif TM, Parikh SA, Vahl TP, Ali ZA, Karmpaliotis D, Rabbani LE, Collins MB, Leon MB, McEntegart MB, Moses JW, Kirtane AJ, Mintz GS, Maehara A. Yamamoto K, et al. EuroIntervention. 2023 Jun 7:EIJ-D-23-00107. doi: 10.4244/EIJ-D-23-00107. Online ahead of print. EuroIntervention. 2023. PMID: 37283548
Primary ISR mechanisms were classified as follows: 1) neointimal hyperplasia (NIH); 2) neoatherosclerosis; 3) ostium not covered by the stent; 4) stent fracture or deformation; 5) stent underexpansion (old minimum stent area <4.0 mm(2) or stent expansion <50%); or 6) …
Primary ISR mechanisms were classified as follows: 1) neointimal hyperplasia (NIH); 2) neoatherosclerosis; 3) ostium not covered by t …
Use of Next Generation Sequencing in a State-Wide Strategy of HIV-1 Surveillance: Impact of the SARS-CoV-2 Pandemic on HIV-1 Diagnosis and Transmission.
Zhou S, Long N, Moeser M, Hill CS, Samoff E, Mobley V, Frost S, Bayer C, Kelly E, Greifinger A, Shone S, Glover W, Clark M, Eron J, Cohen M, Swanstrom R, Dennis AM. Zhou S, et al. J Infect Dis. 2023 Jun 7:jiad211. doi: 10.1093/infdis/jiad211. Online ahead of print. J Infect Dis. 2023. PMID: 37283544
BACKGROUND: The ongoing SARS-CoV-2 pandemic posed an unpreceded threat to the management of other pandemics such as HIV-1 in the United States. The full impact of the SARS-CoV-2 pandemic on the HIV-1 pandemic needs to be evaluated. METHODS: All individuals with newl …
BACKGROUND: The ongoing SARS-CoV-2 pandemic posed an unpreceded threat to the management of other pandemics such as HIV-1 in the United …
Dynamic neural reconstructions of attended object location and features using EEG.
Chen J, Golomb JD. Chen J, et al. J Neurophysiol. 2023 Jun 7. doi: 10.1152/jn.00180.2022. Online ahead of print. J Neurophysiol. 2023. PMID: 37283457
To answer this question, it is critical to have tools that accurately recover neural representations of both feature and location information with high temporal resolution. In the current study, we used human electroencephalography (EEG) and machine learning to explore how …
To answer this question, it is critical to have tools that accurately recover neural representations of both feature and location informatio …
Factors associated with life satisfaction in systemic sclerosis: Examining the moderating roles of social support and spiritual well-being.
Chen YT, Murphy SL, Furst DE, Clements P, Kafaja S, Tsevat J, Malcarne V, Khanna D. Chen YT, et al. J Scleroderma Relat Disord. 2023 Jun;8(2):107-112. doi: 10.1177/23971983221146366. Epub 2023 Feb 8. J Scleroderma Relat Disord. 2023. PMID: 37283281 Free PMC article.
OBJECTIVES: Systemic sclerosis often has a significant impact on an individual's quality of life. Life satisfaction is a subjective expression of well-being and a key component of quality of life. ...
OBJECTIVES: Systemic sclerosis often has a significant impact on an individual's quality of life. Life satisfaction is a subjective e …
Testing of sand from recreational areas and sandpits in Warsaw, for presence of Ascaris Lumbricoides and Toxocara spp.
Matras A, Stasiak A, Chmielewski T, Kaczmarek A. Matras A, et al. Przegl Epidemiol. 2023;77(1):53-58. doi: 10.32394/pe.77.05. Przegl Epidemiol. 2023. PMID: 37283278
INTRODUCTION: Improper maintenance of the cleanliness of sand in sandboxes can be a source of human pathogenic helminths, including Toxocara spp., Enterobius vermicularis, Ascaris lumbricoides, leading to parasitic infections. AIM OF THE STUDY: The purpose of this study wa …
INTRODUCTION: Improper maintenance of the cleanliness of sand in sandboxes can be a source of human pathogenic helminths, including T …
Rethinking systemic ableism: A response to Zagouras, Ellick, and Aulisio.
Andrews EE, Ayers KB, Stramondo JA, Powell RM. Andrews EE, et al. Clin Ethics. 2023 Mar;18(1):7-12. doi: 10.1177/14777509221094472. Epub 2022 Apr 20. Clin Ethics. 2023. PMID: 37283273 Free PMC article.
Her health care team questioned her decision-making capacity based on her alleged "mental age" and experiences of being sheltered and excluded. ...This is a classic example of discriminatory and culturally incompetent reproductive health care for a disabled woman... …
Her health care team questioned her decision-making capacity based on her alleged "mental age" and experiences of being sheltered and …
A monoclonal antibody raised against human EZH2 cross-reacts with the RNA-binding protein SAFB.
Cherney RE, Mills CA, Herring LE, Braceros AK, Calabrese JM. Cherney RE, et al. Biol Open. 2023 Jun 15;12(6):bio059955. doi: 10.1242/bio.059955. Epub 2023 Jun 7. Biol Open. 2023. PMID: 37283223
We report that a broadly used rabbit monoclonal antibody raised against human EZH2, a catalytic subunit of PRC2, cross-reacts with an RNA-binding protein called Scaffold Attachment Factor B (SAFB) in mouse embryonic stem cells (ESCs) under buffer conditions that are common …
We report that a broadly used rabbit monoclonal antibody raised against human EZH2, a catalytic subunit of PRC2, cross-reacts with an …
Are child maltreatment and intimate partner violence associated with adult disordered eating?
Lebed O, Sabina C, Pacanowski CR, Jaremka LM. Lebed O, et al. Int J Eat Disord. 2023 Jun 7. doi: 10.1002/eat.23972. Online ahead of print. Int J Eat Disord. 2023. PMID: 37283219
OBJECTIVE: Disordered eating is one of the most prevalent mental health concerns (Galmiche et al., 2019, Quick & Byrd-Bredbenner, 2013, Neumark-Sztainer et al., 2006). ...METHOD: We use data from 14,332 people from Wave III of the National Longitudinal Study of …
OBJECTIVE: Disordered eating is one of the most prevalent mental health concerns (Galmiche et al., 2019, Quick & Byrd-Bredbenner, …
Childhood adversity during the post-apartheid transition and COVID-19 stress independently predict adult PTSD risk in urban South Africa: A biocultural analysis of the stress sensitization hypothesis.
Kim AW, Said Mohamed R, Norris SA, Naicker S, Richter LM, Kuzawa CW. Kim AW, et al. Am J Biol Anthropol. 2023 Jun 7. doi: 10.1002/ajpa.24791. Online ahead of print. Am J Biol Anthropol. 2023. PMID: 37283092
Scientists have suggested that psychosocial stress and trauma during childhood may increase one's vulnerability to the mental health consequences of future stressors-a process known as stress sensitization. ...Adults who reported greater childhood adversity exhibite …
Scientists have suggested that psychosocial stress and trauma during childhood may increase one's vulnerability to the mental heal …
Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin.
Sakashita A, Ooga M, Otsuka K, Maezawa S, Takeuchi C, Wakayama S, Wakayama T, Namekawa SH. Sakashita A, et al. Nucleic Acids Res. 2023 Jun 7:gkad479. doi: 10.1093/nar/gkad479. Online ahead of print. Nucleic Acids Res. 2023. PMID: 37283086
Sperm chromatin retains small amounts of histones, and chromatin states of sperm mirror gene expression programs of the next generation. ...By applying modified methods of assisted reproductive technology using testicular sperm, we rescued infertility of mice missing Polyc …
Sperm chromatin retains small amounts of histones, and chromatin states of sperm mirror gene expression programs of the next generati …
Adult-onset depletion of sulfatide leads to axonal degeneration with relative myelin sparing.
Dustin E, McQuiston AR, Honke K, Palavicini JP, Han X, Dupree JL. Dustin E, et al. Glia. 2023 Jun 7. doi: 10.1002/glia.24423. Online ahead of print. Glia. 2023. PMID: 37283058
3-O-sulfogalactosylceramide (sulfatide) constitutes a class of sphingolipids that comprise about 4% of myelin lipids in the central nervous system. Previously, our group characterized a mouse with sulfatide's synthesizing enzyme, cerebroside sulfotransferase (CST), constit …
3-O-sulfogalactosylceramide (sulfatide) constitutes a class of sphingolipids that comprise about 4% of myelin lipids in the central nervous …
Tackling dynamic prediction of death in patients with recurrent cardiovascular events.
Liang M, Li Z, Li L, Chinchilli VM, Zhang L, Wang M. Liang M, et al. Stat Med. 2023 Jun 7. doi: 10.1002/sim.9815. Online ahead of print. Stat Med. 2023. PMID: 37282984
Accurately evaluating the prognosis of patients and dynamically predicting the risk of death by considering the historical recurrent events can improve medical decisions and lead to better health care outcomes. Recently proposed joint modeling approaches within the Bayesia …
Accurately evaluating the prognosis of patients and dynamically predicting the risk of death by considering the historical recurrent events …
Muscle force-length dynamics during walking over obstacles indicates delayed recovery and a shift towards more 'strut-like' function in birds with proprioceptive deficit.
Schwaner MJ, Gordon JC, Biewener A, Daley MA. Schwaner MJ, et al. J Exp Biol. 2023 Jun 7:jeb.245199. doi: 10.1242/jeb.245199. Online ahead of print. J Exp Biol. 2023. PMID: 37282982
In contrast, Etot of rLG increased by 31% in S 0 strides compared to level, but also increased by 43% in the first post-obstacle (S+1) stride. In iLG, muscle force and work differed significantly from level only in the S 0 stride, indicating a single-stride r …
In contrast, Etot of rLG increased by 31% in S 0 strides compared to level, but also increased by 43% in the first post-obstacle ( …
Cardiac effects 2 years after successful non-myeloablative human leukocyte antigen-matched related donor hematopoietic cell transplants in sickle cell disease.
Sachdev V, Limerick E, Nguyen ML, Li W, Jeffries N, Ramachandra S, Tofovic D, Rondelli D, Al Zahrani M, Aljizeeri A, Saraf S, Hsieh M, Fitzhugh CD. Sachdev V, et al. Am J Hematol. 2023 Jun 7. doi: 10.1002/ajh.26985. Online ahead of print. Am J Hematol. 2023. PMID: 37282828 No abstract available.
Epigenetic Regulation of Hepatic Lipid Metabolism by DNA Methylation.
Wang S, Zha L, Cui X, Yeh YT, Liu R, Jing J, Shi H, Chen W, Hanover J, Yin J, Yu L, Xue B, Shi H. Wang S, et al. Adv Sci (Weinh). 2023 Jun 6:e2206068. doi: 10.1002/advs.202206068. Online ahead of print. Adv Sci (Weinh). 2023. PMID: 37282749
Associations between polymorphisms in leptin and leptin receptor genes and colorectal cancer survival.
Du M, Wang Y, Vallis J, Shariati M, Parfrey PS, Mclaughlin JR, Wang PP, Zhu Y. Du M, et al. Cancer Biol Med. 2023 Jun 6:j.issn.2095-3941.2022.0635. doi: 10.20892/j.issn.2095-3941.2022.0635. Online ahead of print. Cancer Biol Med. 2023. PMID: 37282602
Data on their demographics and lifestyles were collected via questionnaires. Genotyping of blood samples was performed with the Illumina Human Omni-Quad Bead chip. Multivariable Cox models were used to assess the relationships of 35 tag single-nucleotide polymorphisms (SNP …
Data on their demographics and lifestyles were collected via questionnaires. Genotyping of blood samples was performed with the Illumina …
An epigenetic synopsis of parental substance use.
Lo JO, D'Mello RJ, Watch L, Schust DJ, Murphy SK. Lo JO, et al. Epigenomics. 2023 Jun 7. doi: 10.2217/epi-2023-0064. Online ahead of print. Epigenomics. 2023. PMID: 37282544 Review.
Emerging evidence suggests that paternal pre-conception and maternal prenatal substance use may alter offspring epigenetic regulation (changes to gene expression without modifying DNA) and outcomes later in life, including neurodevelopment and mental health. However, relat …
Emerging evidence suggests that paternal pre-conception and maternal prenatal substance use may alter offspring epigenetic regulation (chang …
"Floppy brain" in congenital hydrocephalus.
Duy PQ, Kahle KT. Duy PQ, et al. Cereb Cortex. 2023 Jun 6:bhad206. doi: 10.1093/cercor/bhad206. Online ahead of print. Cereb Cortex. 2023. PMID: 37280765
After CSF was drained from the ventricle intraoperatively, the patient's cortical mantle collapsed and exhibited a "floppy" appearance on neuroimaging, suggesting an inability of the hydrocephalic brain to maintain its structural integrity. The case provides clinical suppo …
After CSF was drained from the ventricle intraoperatively, the patient's cortical mantle collapsed and exhibited a "floppy" appearanc …
Lipid production and cellular changes in Fremyella diplosiphon exposed to nanoscale zerovalent iron nanoparticles and ampicillin.
Yalcin YS, Aydin B, Chen H, Gichuki S, Sitther V. Yalcin YS, et al. Microb Cell Fact. 2023 Jun 7;22(1):108. doi: 10.1186/s12934-023-02113-2. Microb Cell Fact. 2023. PMID: 37280676 Free PMC article.
As lipid-enriched energy stocks, cyanobacteria are the leading group of microorganisms contributing to the advent of a new energy era. In the present study, the impact of Nanofer 25 s nanoscale zero-valent iron nanoparticles (nZVIs) and ampicillin on lipid production and c …
As lipid-enriched energy stocks, cyanobacteria are the leading group of microorganisms contributing to the advent of a new energy era. In th …
Psychosocial stressors and current e-cigarette use in the youth risk behavior survey.
Erhabor J, Boakye E, Osuji N, Obisesan O, Osei AD, Mirbolouk H, Stokes AC, Dzaye O, El-Shahawy O, Rodriguez CJ, Hirsch GA, Benjamin EJ, DeFilippis AP, Robertson RM, Bhatnagar A, Blaha MJ. Erhabor J, et al. BMC Public Health. 2023 Jun 6;23(1):1080. doi: 10.1186/s12889-023-16031-w. BMC Public Health. 2023. PMID: 37280552 Free PMC article.
BACKGROUND: This study explores the association between psychosocial stressors and current e-cigarette use among adolescents in the United States. METHODS: We used data from 12,767 participants in the 2019 National Youth Risk Behavioral Survey to examine the …
BACKGROUND: This study explores the association between psychosocial stressors and current e-cigarette use among adolescents in the Unite …
Association of plasma aflatoxin with persistent detection of oncogenic human papillomaviruses in cervical samples from Kenyan women enrolled in a longitudinal study.
Tong Y, Tonui P, Orang'o O, Zhang J, Maina T, Muthoka K, Groopman J, Smith J, Madeen E, Ermel A, Loehrer P, Brown DR. Tong Y, et al. BMC Infect Dis. 2023 Jun 6;23(1):377. doi: 10.1186/s12879-023-08323-8. BMC Infect Dis. 2023. PMID: 37280534 Free PMC article.
BACKGROUND: Cervical cancer is caused by oncogenic human papillomaviruses (HR-HPV) and is common among Kenyan women. ...
BACKGROUND: Cervical cancer is caused by oncogenic human papillomaviruses (HR-HPV) and is common among Kenyan women. ...
Influence of analytic methods, data sources, and repeated measurements on the population attributable fraction of lifestyle risk factors.
Wu Y, Kim H, Wang K, Song M, Wang M, Tamimi R, Eliassen H, Smith-Warner SA, Willett WC, Giovannucci EL. Wu Y, et al. Eur J Epidemiol. 2023 Jun 6. doi: 10.1007/s10654-023-01018-z. Online ahead of print. Eur J Epidemiol. 2023. PMID: 37280503
Three statistical methods to estimate PAR% were identified from a systematic literature review: the Levin's formula, the comparative incidence rate method, and the comparative risk assessment method. We compared the variations in PAR% of postmenopausal breast cancer in the …
Three statistical methods to estimate PAR% were identified from a systematic literature review: the Levin's formula, the comparative …
The Role of Adverse Pregnancy Outcomes in Conventional Cardiovascular Risk Prediction.
Reddy SM, Wiecha N, Nguyen CT, Barch DH. Reddy SM, et al. Matern Child Health J. 2023 Jun 6. doi: 10.1007/s10995-023-03725-1. Online ahead of print. Matern Child Health J. 2023. PMID: 37280462
OBJECTIVE: Approximately one-third of women in the U.S. experience an adverse pregnancy outcome (APO), which are recognized as sex-specific cardiovascular disease (CVD) risk factors. ...METHODS: Women, age 40-79, with a pregnancy history and no pre-existing CVD were …
OBJECTIVE: Approximately one-third of women in the U.S. experience an adverse pregnancy outcome (APO), which are recognized as …
Trust your gut or trust your ultrasound?
Rolfzen ML, Bartels K. Rolfzen ML, et al. Can J Anaesth. 2023 Jun 6. doi: 10.1007/s12630-023-02507-1. Online ahead of print. Can J Anaesth. 2023. PMID: 37280457 English. No abstract available.
Deep-learning CT reconstruction in clinical scans of the abdomen: a systematic review and meta-analysis.
Shehata MA, Saad AM, Kamel S, Stanietzky N, Roman-Colon AM, Morani AC, Elsayes KM, Jensen CT. Shehata MA, et al. Abdom Radiol (NY). 2023 Jun 6. doi: 10.1007/s00261-023-03966-2. Online ahead of print. Abdom Radiol (NY). 2023. PMID: 37280374
METHODS: We used PubMed, Scopus, Embase, and Web of Science to conduct systematic searches for studies assessing the most common commercially available deep-learning CT reconstruction algorithms: True Fidelity (TF) and Advanced intelligent Clear-IQ Engine (AiCE) in the abdomen of …
METHODS: We used PubMed, Scopus, Embase, and Web of Science to conduct systematic searches for studies assessing the most common commerciall …
Mapping human norovirus antigens during infection reveals the breadth of the humoral immune response.
Su L, Huang W, Neill FH, Estes MK, Atmar RL, Palzkill T. Su L, et al. NPJ Vaccines. 2023 Jun 6;8(1):87. doi: 10.1038/s41541-023-00683-1. NPJ Vaccines. 2023. PMID: 37280322 Free PMC article.
Human noroviruses (HuNoV) are the leading cause of acute gastroenteritis worldwide. ...The results demonstrate that genomic phage display coupled with deep sequencing can characterize HuNoV antigenic landscapes from complex polyclonal human sera to reveal the timing …
Human noroviruses (HuNoV) are the leading cause of acute gastroenteritis worldwide. ...The results demonstrate that genomic phage dis …
Molecular basis for the recognition of 24-(S)-hydroxycholesterol by integrin αvβ3.
Gc JB, Chen J, Pokharel SM, Mohanty I, Mariasoosai C, Obi P, Panipinto P, Bandyopadhyay S, Bose S, Natesan S. Gc JB, et al. Sci Rep. 2023 Jun 6;13(1):9166. doi: 10.1038/s41598-023-36040-4. Sci Rep. 2023. PMID: 37280310 Free PMC article.
Our previous study demonstrated that 25HC induces an innate immune response during viral infections by activating the integrin-focal adhesion kinase (FAK) pathway. 25HC produced the proinflammatory response by binding directly to integrins at a novel binding site (site II) and tr …
Our previous study demonstrated that 25HC induces an innate immune response during viral infections by activating the integrin-focal adhesio …
Circadian desynchronization disrupts physiological rhythms of prefrontal cortex pyramidal neurons in mice.
Roberts BL, Karatsoreos IN. Roberts BL, et al. Sci Rep. 2023 Jun 6;13(1):9181. doi: 10.1038/s41598-023-35898-8. Sci Rep. 2023. PMID: 37280307 Free PMC article.
Yet how disruption of daily rhythms impacts the fundamental function of PFC neurons, and the mechanism(s) by which this occurs, remains unknown. Using a mouse model, we demonstrate that the activity and action potential dynamics of prelimbic PFC neurons are regulated by ti …
Yet how disruption of daily rhythms impacts the fundamental function of PFC neurons, and the mechanism(s) by which this occurs, remai …
Opposite modulation of functional recovery following contusive spinal cord injury in mice with oligodendrocyte-selective deletions of Atf4 and Chop/Ddit3.
Gao Y, Wei GZ, Forston MD, Rood B, Hodges ER, Burke D, Andres K, Morehouse J, Armstrong C, Glover C, Slomnicki LP, Ding J, Chariker JH, Rouchka EC, Saraswat Ohri S, Whittemore SR, Hetman M. Gao Y, et al. Sci Rep. 2023 Jun 6;13(1):9193. doi: 10.1038/s41598-023-36258-2. Sci Rep. 2023. PMID: 37280306 Free PMC article.
Barriers and solutions to the adoption of translational tools for computational psychiatry.
Benrimoh D, Fisher V, Mourgues C, Sheldon AD, Smith R, Powers AR. Benrimoh D, et al. Mol Psychiatry. 2023 Jun 6. doi: 10.1038/s41380-023-02114-y. Online ahead of print. Mol Psychiatry. 2023. PMID: 37280282 Review.
Computational psychiatry is a field aimed at developing formal models of information processing in the human brain, and how alterations in this processing can lead to clinical phenomena. ...
Computational psychiatry is a field aimed at developing formal models of information processing in the human brain, and how alteratio …
A novel strategy to characterize the pattern of β-lactam antibiotic-induced drug resistance in Acinetobacter baumannii.
Hillyer T, Benin BM, Sun C, Aguirre N, Willard B, Sham YY, Shin WS. Hillyer T, et al. Sci Rep. 2023 Jun 6;13(1):9177. doi: 10.1038/s41598-023-36475-9. Sci Rep. 2023. PMID: 37280269 Free PMC article.
Carbapenem-resistant Acinetobacter baumannii (CRAb) is an urgent public health threat, according to the CDC. This pathogen has few treatment options and causes severe nosocomial infections with > 50% fatality rate. ...
Carbapenem-resistant Acinetobacter baumannii (CRAb) is an urgent public health threat, according to the CDC. This pathogen has few tr …
Establishment and characterization of patient-derived xenograft of a rare pediatric anaplastic pleomorphic xanthoastrocytoma (PXA) bearing a CDC42SE2-BRAF fusion.
Damayanti NP, Saadatzadeh MR, Dobrota E, Ordaz JD, Bailey BJ, Pandya PH, Bijangi-Vishehsaraei K, Shannon HE, Alfonso A, Coy K, Trowbridge M, Sinn AL, Zhang ZY, Gallagher RI, Wulfkuhle J, Petricoin E, Richardson AM, Marshall MS, Lion A, Ferguson MJ, Balsara KE, Pollok KE. Damayanti NP, et al. Sci Rep. 2023 Jun 6;13(1):9163. doi: 10.1038/s41598-023-36107-2. Sci Rep. 2023. PMID: 37280243 Free PMC article.
Whole exome sequencing (WES) demonstrated a high degree of conservation in the genomic landscape between PDX and matched human tumor, including small variants (Pearson's r = 0.794-0.839) and tumor mutational burden (~ 3 mutations/MB). ...Moreover, chromosomal rearra …
Whole exome sequencing (WES) demonstrated a high degree of conservation in the genomic landscape between PDX and matched human tumor, …
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase.
Zmudzinski M, Rut W, Olech K, Granda J, Giurg M, Burda-Grabowska M, Kaleta R, Zgarbova M, Kasprzyk R, Zhang L, Sun X, Lv Z, Nayak D, Kesik-Brodacka M, Olsen SK, Weber J, Hilgenfeld R, Jemielity J, Drag M. Zmudzinski M, et al. Sci Rep. 2023 Jun 6;13(1):9161. doi: 10.1038/s41598-023-35907-w. Sci Rep. 2023. PMID: 37280236 Free PMC article.
PIE-seq: identifying RNA-binding protein targets by dual RNA-deaminase editing and sequencing.
Ruan X, Hu K, Zhang X. Ruan X, et al. Nat Commun. 2023 Jun 6;14(1):3275. doi: 10.1038/s41467-023-39054-8. Nat Commun. 2023. PMID: 37280234 Free PMC article.
Here we present PIE-Seq to investigate Protein-RNA Interaction with dual-deaminase Editing and Sequencing by conjugating C-to-U and A-to-I base editors to RBPs. We benchmark PIE-Seq and demonstrate its sensitivity in single cells, its application in the developing brain, a …
Here we present PIE-Seq to investigate Protein-RNA Interaction with dual-deaminase Editing and Sequencing by conjugating C-to-U and A …
Preferential rabbit antibody responses to C-termini of NOTCH3 peptide immunogens.
Lee SJ, Gasche MB, Burrows CJ, Kondepudi A, Zhang X, Wang MM. Lee SJ, et al. Sci Rep. 2023 Jun 6;13(1):9156. doi: 10.1038/s41598-023-36067-7. Sci Rep. 2023. PMID: 37280231 Free PMC article.
To shed light on the frequency of preferential rabbit antibody responses to C-termini of peptide immunogens, we present our experience with generation of rabbit antibodies to human NOTCH3. A total of 23 antibodies were raised against 10 peptide sequences of human NO …
To shed light on the frequency of preferential rabbit antibody responses to C-termini of peptide immunogens, we present our experience with …
Drug screening at single-organoid resolution via bioprinting and interferometry.
Tebon PJ, Wang B, Markowitz AL, Davarifar A, Tsai BL, Krawczuk P, Gonzalez AE, Sartini S, Murray GF, Nguyen HTL, Tavanaie N, Nguyen TL, Boutros PC, Teitell MA, Soragni A. Tebon PJ, et al. Nat Commun. 2023 Jun 6;14(1):3168. doi: 10.1038/s41467-023-38832-8. Nat Commun. 2023. PMID: 37280220 Free PMC article.
Traditional platforms use two-dimensional cultures which do not accurately reflect the biology of human tumors. More clinically relevant model systems such as three-dimensional tumor organoids can be difficult to scale and screen. ...
Traditional platforms use two-dimensional cultures which do not accurately reflect the biology of human tumors. More clinically relev …
Chromatin alternates between A and B compartments at kilobase scale for subgenic organization.
Harris HL, Gu H, Olshansky M, Wang A, Farabella I, Eliaz Y, Kalluchi A, Krishna A, Jacobs M, Cauer G, Pham M, Rao SSP, Dudchenko O, Omer A, Mohajeri K, Kim S, Nichols MH, Davis ES, Gkountaroulis D, Udupa D, Aiden AP, Corces VG, Phanstiel DH, Noble WS, Nir G, Di Pierro M, Seo JS, Talkowski ME, Aiden EL, Rowley MJ. Harris HL, et al. Nat Commun. 2023 Jun 6;14(1):3303. doi: 10.1038/s41467-023-38429-1. Nat Commun. 2023. PMID: 37280210 Free PMC article.
We then identify diffuse interactions that radiate from CTCF loop anchors, which correlate with strong enhancer-promoter interactions and proximal transcription. We also find that these diffuse interactions depend on CTCF's RNA binding domains. In this work, we demonstrate …
We then identify diffuse interactions that radiate from CTCF loop anchors, which correlate with strong enhancer-promoter interactions and pr …
Financial hardship, sleep disturbances, and their relationship among men and women in the United States during the COVID-19 pandemic.
Gaston SA, Strassle PD, Alhasan DM, Pérez-Stable EJ, Nápoles AM, Jackson CL. Gaston SA, et al. Sleep Health. 2023 Jun 4:S2352-7218(23)00086-4. doi: 10.1016/j.sleh.2023.04.007. Online ahead of print. Sleep Health. 2023. PMID: 37280141 Free PMC article.
OBJECTIVE: In the United States (US), the health and financial consequences of COVID-19 have disproportionately impacted women and minoritized racial-ethnic groups. Yet, few US studies have investigated financial hardship during the COVID-19 pandemic and slee …
OBJECTIVE: In the United States (US), the health and financial consequences of COVID-19 have disproportionately impacte …
Inflammatory Bowel Disease in Appalachian Kentucky: An Investigation of Outcomes and Health Care Utilization.
Rhudy CN, Perry CL, Hawk GS, Flomenhoft DR, Talbert JC, Barrett TA. Rhudy CN, et al. Inflamm Bowel Dis. 2023 Jun 6:izad096. doi: 10.1093/ibd/izad096. Online ahead of print. Inflamm Bowel Dis. 2023. PMID: 37280118
Data were reported as crude and age-adjusted rates of visits per 100,000 population per year collected in 2016 to 2019. National inpatient discharge data from 2019, stratified by rural and urban classification codes, were utilized to compare Kentucky to national tre …
Data were reported as crude and age-adjusted rates of visits per 100,000 population per year collected in 2016 to 2019. National inpa …
Recoding UAG to selenocysteine in Saccharomyces cerevisiae.
Hoffman KS, Chung CZ, Mukai T, Krahn N, Jang HK, Balasuriya N, O'Donoghue P, Söll D. Hoffman KS, et al. RNA. 2023 Jun 6:rna.079658.123. doi: 10.1261/rna.079658.123. Online ahead of print. RNA. 2023. PMID: 37279998 Free article.
Based on our previous development of efficient selenoprotein production in bacteria, we designed a novel selenocysteine biosynthesis pathway in Saccharomyces cerevisiae using Aeromonas salmonicida translation components. S. cerevisiae tRNASer was mutated to resemble A. sal …
Based on our previous development of efficient selenoprotein production in bacteria, we designed a novel selenocysteine biosynthesis pathway …