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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 3
1947 4
1948 3
1949 3
1950 3
1951 11
1952 9
1953 6
1954 12
1955 7
1956 5
1957 14
1958 14
1959 17
1960 19
1961 19
1962 23
1963 46
1964 61
1965 70
1966 180
1967 215
1968 214
1969 200
1970 209
1971 186
1972 199
1973 231
1974 297
1975 369
1976 408
1977 603
1978 982
1979 1194
1980 15685
1981 33527
1982 34552
1983 35009
1984 36722
1985 37425
1986 38598
1987 39963
1988 41078
1989 42720
1990 44831
1991 46118
1992 46704
1993 47438
1994 48932
1995 49323
1996 49509
1997 49843
1998 50835
1999 52357
2000 54945
2001 56286
2002 59381
2003 63600
2004 71262
2005 77912
2006 86523
2007 93097
2008 103266
2009 110078
2010 119481
2011 128545
2012 133207
2013 138265
2014 139645
2015 140787
2016 136180
2017 131626
2018 134165
2019 136088
2020 148724
2021 156091
2022 143683
2023 144925
2024 140196
2025 133790
2026 44418
2027 2

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3,526,933 results

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Page 1
Social vulnerability shapes deep clinical phenotypes and brain health in aging and dementia across Latin America.
Farombi T, Azzi T, Legaz A, Aguillón D, Avila-Funes JA, Behrens MI, Bruno M, Cardona JF, Custodio N, Delgado C, Pina-Escudero S, Galofre MDPG, Maito M, Magrath-Guimet N, Miller JB, Matallana D, de Oliveira MO, Rocatti G, Resende EPF, Slachevsky A, Takada L, Wen O, Zapata-Restrepo LM, Lawlor B, Yaffe K, Hu K, Miller B, Possin K, Yokoyama JS, Fittipaldi S, García AM, Larzabal HH, Santamaria-Garcia H, Tagliazzuchi E, Duran-Aniotz C, Ibanez A, Migeot J. Farombi T, et al. Alzheimers Dement. 2026 Jun;22(6):e71534. doi: 10.1002/alz.71534. Alzheimers Dement. 2026. PMID: 42251497
A life-course questionnaire captured eight domains of social vulnerability, used to derive a social vulnerability index and latent vulnerability profiles. Brain health was characterized across 37 cognitive, functional, mental health, and dementia sever …
A life-course questionnaire captured eight domains of social vulnerability, used to derive a social vulnerability index and la …
Intraindividual cognitive variability predicts amyloid beta, tau PET, and dementia conversion in Down syndrome: a potential marker of cognitive resilience.
Fonseca LM, Lila E, Shojaie A, Chhatwal J, Forlenza O, Beeri MS, Krinsky-McHale S, Cohen AD, Christian BT, Head E, Mapstone M, Handen B, Ances BM, Grabowski T, Chaytor NS, Zaman S; Alzheimer's Biomarkers Consortium‐ Down Syndrome (ABC‐DS) Investigators. Fonseca LM, et al. Alzheimers Dement. 2026 Jun;22(6):e71537. doi: 10.1002/alz.71537. Alzheimers Dement. 2026. PMID: 42251495
Hypertension, use of antihypertensive medications and breast cancer survival among Black women.
Barnard ME, Xu NN, Holder EX, Jones D, Nayor M, Ko NY, Palmer JR. Barnard ME, et al. Breast Cancer Res. 2026 Jun 6. doi: 10.1186/s13058-026-02317-5. Online ahead of print. Breast Cancer Res. 2026. PMID: 42251447 Free article.
We examined these associations among 2474 Black Women's Health Study participants with invasive breast cancer. Hypertension and antihypertensive medication use were assessed biennially, and breast cancer diagnoses were confirmed through medical records and cancer re …
We examined these associations among 2474 Black Women's Health Study participants with invasive breast cancer. Hypertension an …
FKBP51 inhibition by SAFit2 modulates tau pathology and cognitive deficits in PS19 mice.
Contreras-Marciales A, Mezquite-Garcia D, Verdina LA, Elnahrawy A, Wolf T, Guergues J, Parikh P, Hunter ER, Hernandez Acosta D, Stevens SM Jr, Hill SE, Blair LJ. Contreras-Marciales A, et al. Alzheimers Res Ther. 2026 Jun 6. doi: 10.1186/s13195-026-02107-3. Online ahead of print. Alzheimers Res Ther. 2026. PMID: 42251444 Free article.
The Chile BiLS case-control study of gallbladder cancer.
Koshiol J, Van De Wyngard V, Argirion I, Marco C, Pozo Diaz MA, Reyes Romero IN, Cook P, Pfeiffer RM, Mardones N, Medina K, Olivo V, Pettit K, Sanchez R, Villaseca M, Bellolio E, Losada H, Roa JC, Hildesheim A, Aresse M, Ferreccio C, Araya JC; Chile BiLS Study Group. Koshiol J, et al. Arch Public Health. 2026 Jun 6. doi: 10.1186/s13690-026-01977-1. Online ahead of print. Arch Public Health. 2026. PMID: 42251441 Free article.
Assessing PRISM context domains and RE-AIM outcomes: data from use of the iterative PRISM webtool.
Glasgow RE, Ford BS, Ying J, Rodriguez C, Rabin BA, Trinkley KE. Glasgow RE, et al. Implement Sci Commun. 2026 Jun 6. doi: 10.1186/s43058-026-00982-3. Online ahead of print. Implement Sci Commun. 2026. PMID: 42251416 Free article.
RESULTS: A total of 348 clinical, community, and public health respondents completed the iPRISM survey using the publicly available webtool. They reported on projects from a wide variety of clinical, community, and public health settings; in English and Spanish; and …
RESULTS: A total of 348 clinical, community, and public health respondents completed the iPRISM survey using the publicly available w …
Leveraging lived experience: a qualitative study on the impact of formerly incarcerated consultants in public policy making to improve safety net services.
Candelario J, Zúñiga D, Lee D, Abwoon C, Arevalo S, Casillas Gonzalez M, Garcia J, Garcia S, Glenn L, Johnson G, Morris J, Huynh T, Wiley Y, Brown AF, Carson SL. Candelario J, et al. Harm Reduct J. 2026 Jun 6. doi: 10.1186/s12954-026-01484-0. Online ahead of print. Harm Reduct J. 2026. PMID: 42251333 Free article.
BACKGROUND: Los Angeles County-wide criminal justice reform and policy decision-making focused on reentry and diversion from incarceration usually include only the voices of law enforcement and other public-sector employees, with little input from impacted community members. The …
BACKGROUND: Los Angeles County-wide criminal justice reform and policy decision-making focused on reentry and diversion from incarceration u …
Impact of sample processing method and volume on 16 S rRNA profiling of the urobiome.
Ramirez SC, Lewis ZJ, Hale VL, Coffey EL. Ramirez SC, et al. BMC Microbiol. 2026 Jun 6. doi: 10.1186/s12866-026-05274-3. Online ahead of print. BMC Microbiol. 2026. PMID: 42251288 Free article.
BACKGROUND: The urinary microbiome (urobiome) plays important roles in both human and animal urogenital tract health. Characterization of these microbial communities presents several technical challenges, largely due to the low microbial biomass of urine. ...
BACKGROUND: The urinary microbiome (urobiome) plays important roles in both human and animal urogenital tract health. Characte …
Racial Disparities in Tobacco Smoking-Related Risks for Lung Cancer: A Systematic Review & Meta-analysis.
Williams RM, Singh S, Luo Y, Smith L, Connors G, Taylor KL, Adams-Campbell L, Makambi KH, Dash C. Williams RM, et al. J Racial Ethn Health Disparities. 2026 Jun 6. doi: 10.1007/s40615-026-03030-x. Online ahead of print. J Racial Ethn Health Disparities. 2026. PMID: 42251222 Review.
METHODS: We conducted a systematic review and meta-analysis of U.S.-based observational studies from 1964 to June 2024. Eligible studies examined lung cancer incidence as the primary outcome and reported race-specific estimates for smoking-related risk. ...
METHODS: We conducted a systematic review and meta-analysis of U.S.-based observational studies from 1964 to June 2024. Eligib …
Cortico-pallidal beta dynamics underlie impaired turning in Parkinson's disease.
Shukla PD, Bath JE, Louie KH, Fekri Azgomi H, Ramesh R, Patelaki E, Marks JH, Balakid JP, Wang DD. Shukla PD, et al. NPJ Parkinsons Dis. 2026 Jun 6. doi: 10.1038/s41531-026-01421-9. Online ahead of print. NPJ Parkinsons Dis. 2026. PMID: 42251056 Free article.
Turning while walking is one of the most common yet complex human movements, and it is frequently impaired in Parkinson's disease (PD), leading to falls and loss of independence. ...
Turning while walking is one of the most common yet complex human movements, and it is frequently impaired in Parkinson's disease (PD …
A multi-ethnic reference map of T cell receptor germline diversity reveals evidence of natural selection on alpha chain genes.
Mantena S, Edahiro R, Okada Y, Akbari A, Raychaudhuri S. Mantena S, et al. Nat Commun. 2026 Jun 6. doi: 10.1038/s41467-026-73730-9. Online ahead of print. Nat Commun. 2026. PMID: 42251052 Free article.
T cell receptors (TCR) orchestrate adaptive immunity, yet the complex, repetitive architecture of the TCR loci has impeded systematic characterization of human genetic variation in the genes encoding the TCR. Using public long-read sequencing data from the Human Pan …
T cell receptors (TCR) orchestrate adaptive immunity, yet the complex, repetitive architecture of the TCR loci has impeded systematic charac …
Hormonal contraceptives and women's sleep health: A systematic review.
Kennedy KER, Boyle JT, Muench A, Thompson MG, Meers JM, Arentson-Lantz EJ, Kline E, Morales KH, Dhaliwal S, Nowakowski S. Kennedy KER, et al. Sleep Med Rev. 2026 Jun 3;89:102309. doi: 10.1016/j.smrv.2026.102309. Online ahead of print. Sleep Med Rev. 2026. PMID: 42250356 Review.
However, there are very few large-scale studies to date that have comprehensively evaluated how hormonal contraceptives influence women's sleep health. The purpose of this systematic review was to synthesize the existing research on hormonal contraceptive use and sleep in …
However, there are very few large-scale studies to date that have comprehensively evaluated how hormonal contraceptives influence women's sl …
Utilization and outcomes of COVID-19 positive donors in pediatric kidney transplantation-a population-based study.
Ranabothu S, Evans MD, Kizilbash SJ. Ranabothu S, et al. Pediatr Nephrol. 2026 Jun 6. doi: 10.1007/s00467-026-07362-y. Online ahead of print. Pediatr Nephrol. 2026. PMID: 42250098
METHODS: Using the Scientific Registry of Transplant Recipients, we identified 143 pediatric kidney recipients (< 18 years) of COVID + donors transplanted between September 2020 and February 2025 and compared them with 1808 recipients of COVID-19 negative (COVID -) donors usin …
METHODS: Using the Scientific Registry of Transplant Recipients, we identified 143 pediatric kidney recipients (< 18 years) of COVID + do …
Measuring affective symptoms of depression in aphasia: development of an accessible ecological momentary assessment tool.
Boxrud B, Siegle E, Shankman SA, Reddy M, Griffith JW, Ashaie SA. Boxrud B, et al. Qual Life Res. 2026 Jun 6;35(7):175. doi: 10.1007/s11136-026-04292-y. Qual Life Res. 2026. PMID: 42250063
PURPOSE: Post-stroke depression is highly prevalent in aphasia, yet existing depression measures rely heavily on language and lack sufficient validity for this population. ...Existing depression measures rely heavily on language and lack sufficient validity for people with …
PURPOSE: Post-stroke depression is highly prevalent in aphasia, yet existing depression measures rely heavily on language and lack su …
Is Pocket Pain Still a Major Issue in Spinal Cord Stimulation?
Scarsbrook MW, Twer AB, Tedford G, Sarmey N, Weinand ME, Pilitsis JG. Scarsbrook MW, et al. Neuromodulation. 2026 May 8:S1094-7159(26)00117-0. doi: 10.1016/j.neurom.2026.04.019. Online ahead of print. Neuromodulation. 2026. PMID: 42249870
Lifespan Trajectories of Asymmetry in White Matter Tracts.
Bogdanov S, Kanakaraj P, Kim ME, Samir J, Gao C, Ramadass K, Rudravaram G, Newlin NR, Archer D, Hohman TJ, Jefferson AL, Morgan VL, Roche A, Englot DJ, Resnick SM, Beason Held LL, Cutting LE, Barquero LA, D'Archangel MA, Nguyen TQ, Humphreys KL, Niu Y, Vinci-Booher S, Cascio CJ; HABS‐HD Study Team; Alzheimer's Disease Neuroimaging Initiative; BIOCARD Study Team; Li Z, Vandekar SN, Zhang P, Gore JC, Forkel SJ, Landman BA, Schilling KG. Bogdanov S, et al. Hum Brain Mapp. 2026 Jun 1;47(8):e70519. doi: 10.1002/hbm.70519. Hum Brain Mapp. 2026. PMID: 42249731
On the Path to Pediatric Genetics: Reflections From Future Clinicians.
Kittock CM, Ceron RH, Buasri K, Capestany C, Vanapruks S, Baxter MF, Plaisted L, Anderson K, Fuchs M, Vavilikolanu A, Shapiro J, Tokhmafshan F, Garlisi-Torales LD. Kittock CM, et al. Am J Med Genet A. 2026 Jun 6. doi: 10.1002/ajmg.a.70189. Online ahead of print. Am J Med Genet A. 2026. PMID: 42249689 No abstract available.
Targeted lipidomics between hPheo1 and SDHB KD cells reveal changes in bioactive lipids and PKC with polyamine pathway inhibition.
Alli AA, Bala N, Xu Y, Denslow ND, Ghayee HK. Alli AA, et al. Physiol Rep. 2026 Jun;14(11):e70894. doi: 10.14814/phy2.70894. Physiol Rep. 2026. PMID: 42249664 Free article.
Polyamine pathway inhibitor N1,N11-diethylnorspermine (DENSPM) was previously shown to inhibit cell growth in progenitor cells derived from a human pheochromocytoma (hPheo1). Here, we hypothesized cell death associated with DENSPM treatment due to altered lipid metabolism …
Polyamine pathway inhibitor N1,N11-diethylnorspermine (DENSPM) was previously shown to inhibit cell growth in progenitor cells derived from …
The evidence for old age motor neuron death: A scoping review.
Cheung SW, Fogarty MJ. Cheung SW, et al. Physiol Rep. 2026 Jun;14(11):e70967. doi: 10.14814/phy2.70967. Physiol Rep. 2026. PMID: 42249658 Free article. Review.
We synthesize PUBMED studies in humans, non-human primates, rats and mice within the spinal cord and brainstem. Attention was given to the methodological approach used to quantify MNs and categorized based on what MNs were quantified (specific pools, vertebral levels, late …
We synthesize PUBMED studies in humans, non-human primates, rats and mice within the spinal cord and brainstem. Attention was given t …
Protein STM3547 From Salmonella typhimurium Is a Phosphofructose Kinase B-Type Enzyme With Ribose Kinase Activity.
McCormick RD, Jabbar AA, Escalante-Semerena JC. McCormick RD, et al. Mol Microbiol. 2026 Jun 5. doi: 10.1111/mmi.70084. Online ahead of print. Mol Microbiol. 2026. PMID: 42249657
Here we identify the function of a hypothetical protein in a human bacterial enteropathogen....
Here we identify the function of a hypothetical protein in a human bacterial enteropathogen....
Kidney outcomes in pure membranous versus proliferative lupus nephritis: A 14-year Latin American cohort study.
Rodelo-Ceballos J, Restrepo-Escobar M, Ustariz J, Taborda A, González LA. Rodelo-Ceballos J, et al. Lupus. 2026 Jun 5:9612033261458574. doi: 10.1177/09612033261458574. Online ahead of print. Lupus. 2026. PMID: 42249630
Compared with PLN, patients with MLN have lower immunological activity, better kidney function, less active urinary sediment at biopsy, and lower modified NIH activity and chronicity indices scores. In multivariable logistic regression, higher eGFR was independently associ …
Compared with PLN, patients with MLN have lower immunological activity, better kidney function, less active urinary sediment at biopsy, and …
A Systematic Review of International Guidelines for Addressing Alcohol Use Disorder in Pregnancy.
Cary CB, Hynes EOB, Terplan M, McNamara KA, Tardelli VS, Fidalgo TM, Bello JK, Doering M, Grucza RA, Jones HE, Duggal R, Kelly JC, Martins SS, Martin CE, Xu KY. Cary CB, et al. Alcohol Clin Exp Res (Hoboken). 2026 Jun;50(6):e70330. doi: 10.1111/acer.70330. Alcohol Clin Exp Res (Hoboken). 2026. PMID: 42249628 Review.
Our final analysis included 18 guidelines from the United States, Canada, the United Kingdom, Australia/New Zealand, and the World Health Organization published from 2014 to the present. Two reviewers independently assessed each guideline using the Appraisal of Guidelines …
Our final analysis included 18 guidelines from the United States, Canada, the United Kingdom, Australia/New Zealand, and the World Health …
Should my child play contact sports?
Patterson Gentile C. Patterson Gentile C. Headache. 2026 Jun 5. doi: 10.1111/head.70141. Online ahead of print. Headache. 2026. PMID: 42249602 No abstract available.
Short Echo-Time Spiral MRSI Versus Single-Voxel Spectroscopy in the Human Brain at 3 Tesla With Semi-LASER Localization.
Park YW, Adanyeguh IM, Henry PG, Deelchand DK. Park YW, et al. Magn Reson Med. 2026 Jun 5. doi: 10.1002/mrm.70463. Online ahead of print. Magn Reson Med. 2026. PMID: 42249576
In this study, we compared the spectral quality and metabolite concentrations obtained using short-T(E) 2D spiral MRSI and SVS in the same region in the human brain at 3T. METHODS: Five healthy subjects were scanned at 3T. 2D spiral MRSI data were acquired in a transverse …
In this study, we compared the spectral quality and metabolite concentrations obtained using short-T(E) 2D spiral MRSI and SVS in the same r …
High-Temporal-Resolution Monitoring of Creatine and Phosphocreatine Dynamics in Skeletal Muscle Using Ultrafast Z-Spectroscopy (UFZ) CEST MRI at 3T.
Ju L, Samuel TJ, Schär M, Wang K, Wu Y, Weiss RG, Xu J. Ju L, et al. Magn Reson Med. 2026 Jun 5. doi: 10.1002/mrm.70464. Online ahead of print. Magn Reson Med. 2026. PMID: 42249575
PURPOSE: To evaluate the feasibility of High-Temporal-Resolution (HTR) Ultrafast Z-spectrum (UFZ) CEST MRI for monitoring the dynamic fluctuations of phosphocreatine (PCr) and creatine (Cr) in human skeletal muscle (SM) at 3 T during and after exercise. METHODS: HTR UFZ-CE …
PURPOSE: To evaluate the feasibility of High-Temporal-Resolution (HTR) Ultrafast Z-spectrum (UFZ) CEST MRI for monitoring the dynamic fluctu …
Novel Variants in PUS7 Associated With Intellectual Disability and Growth Retardation: Expanding the Clinical Spectrum in 13 Patients.
Bergès C, Sauvestre C, Naudion S, Delorme CV, Smol T, Rama M, Moortgat S, Maystadt I, Kersseboom R, Wilke M, Barakat S, Vial Y, Perrin L, Passemard S, Ahmad F, Umair M, Haack T, Grimmel M, Kuechler A, Slavotinek A, Devine P, Hodoglugil U, Zafar F, Afzal E, Dudding-Byth T, Jouret G, Herissant L, Efthymiou S, Houlden H, Legendre M, Michaud V. Bergès C, et al. Clin Genet. 2026 Jun 5. doi: 10.1111/cge.70192. Online ahead of print. Clin Genet. 2026. PMID: 42249560
High stakes: how legal cannabis pricing impacts the illicit market.
Hebert R, Boehnke KF, Joshi S. Hebert R, et al. J Cannabis Res. 2026 Jun 6. doi: 10.1186/s42238-026-00455-3. Online ahead of print. J Cannabis Res. 2026. PMID: 42249514 Free article.
BACKGROUND: Although nearly 80% of Americans reside in a county with a legal, regulated cannabis dispensary, the majority of cannabis consumed in the U.S. is still obtained from unregulated, illicit sources. Illicit cannabis carries greater health risks and i …
BACKGROUND: Although nearly 80% of Americans reside in a county with a legal, regulated cannabis dispensary, the majority of cannabis consum …
DNA methylation-based immune cell profiling in mouse blood using MouseRS-CMD.
Reynolds SR, Stolrow HG, Lee MK, Pike SC, Kolling FW 4th, Channon JY, Mielcarz DW, Ward GA, Fiering SN, Fields J, Salas LA, Christensen BC. Reynolds SR, et al. Genome Biol. 2026 Jun 5. doi: 10.1186/s13059-026-04121-y. Online ahead of print. Genome Biol. 2026. PMID: 42249416 Free article.
Quantitative tandem mass tag-based serum proteomics for longitudinal biomarker monitoring in Duchenne muscular dystrophy.
Naveed A, Recinos E, Chow D, Degan C, Tsonaka R, Guglieri M, Al-Khalili Szigyarto C, Spitali P, van der Burgt YEM, Diaz-Manera J, Dang UJ; FOR-DMD investigators of the Muscle Study Group; Hathout Y. Naveed A, et al. Clin Proteomics. 2026 Jun 6. doi: 10.1186/s12014-026-09613-4. Online ahead of print. Clin Proteomics. 2026. PMID: 42249273 Free article.
Combating Alzheimer's through sleep and exercise (CASE): A study protocol.
Chung D, Larsen BA, Garchitorena Gomez LG, Ramos AR, Kirk-Sanchez NJ, Jean-Louis G, Seixas AA. Chung D, et al. Geroscience. 2026 Jun 6. doi: 10.1007/s11357-026-02337-1. Online ahead of print. Geroscience. 2026. PMID: 42249253
Behavioral interventions-particularly sleep improvement and physical activity-can independently benefit cognition, brain function, and cardiometabolic health, yet their combined (potentially synergistic) effects and scalable delivery models remain underexplored. ...Cogniti …
Behavioral interventions-particularly sleep improvement and physical activity-can independently benefit cognition, brain function, and cardi …
Community-Based Development of Tools to Assess Firearm-Related Attitudes and Beliefs: Associations with Firearm-Related Practices, Social Influences, and Violence Exposure.
Mehari KR, Farrell AD, Coleman JN, Mayinja LS, Walsh CS, Smith PN. Mehari KR, et al. J Community Health. 2026 Jun 5. doi: 10.1007/s10900-026-01587-6. Online ahead of print. J Community Health. 2026. PMID: 42249249
The purpose of this study was to evaluate four novel measures of firearm-related attitudes and beliefs developed through participatory action research, and to determine their associations with firearm-related practices and violence exposure. Participants were a pilot sample of 55 …
The purpose of this study was to evaluate four novel measures of firearm-related attitudes and beliefs developed through participatory actio …
The Role of Microbiome-Associated Metabolites and Their Clinical Implications in Traumatic Brain Injury: A Scoping Review.
Dave AM, Chatrizeh M, Wolf MS, Morowitz MJ, Simon DW. Dave AM, et al. Neurocrit Care. 2026 Jun 5. doi: 10.1007/s12028-026-02562-8. Online ahead of print. Neurocrit Care. 2026. PMID: 42249248 Review.
Traumatic brain injury (TBI) is a major public health challenge, with heterogeneous mechanisms and limited targeted therapies. Despite advances in neurocritical care, interventions to meaningfully alter long-term outcomes have been elusive, and treatment remains largely su …
Traumatic brain injury (TBI) is a major public health challenge, with heterogeneous mechanisms and limited targeted therapies. Despit …
Update on APOL1 and chronic kidney diseases in children.
Varner JD, Ilori TO, Gbadegesin RA. Varner JD, et al. Pediatr Nephrol. 2026 Jun 5. doi: 10.1007/s00467-026-07384-6. Online ahead of print. Pediatr Nephrol. 2026. PMID: 42249201
Chronic kidney disease (CKD) is a major global health burden that disproportionately impacts people of recent African ancestry. The discovery of risk variants in the apolipoprotein L1 (APOL1) gene has transformed the understanding of racial disparities in CKD. ...
Chronic kidney disease (CKD) is a major global health burden that disproportionately impacts people of recent African ancestry. The d …
Super-Bore Aspiration Catheters ( 0.088") in Acute Ischemic Stroke: a Systematic Review and Meta-analysis.
Elek A, Seifuldin M, Yucel S, Bilgin C, Kadirvel R, Kallmes DF, Brinjikji W. Elek A, et al. Clin Neuroradiol. 2026 Jun 5. doi: 10.1007/s00062-026-01687-9. Online ahead of print. Clin Neuroradiol. 2026. PMID: 42249160 Review.
Eligible studies included patients with acute ischemic stroke treated with super-bore aspiration catheters (inner diameter 0.088 inches). Pooled estimates were calculated using random-effects models. ...CONCLUSION: Super-bore aspiration catheters ( 0.088 inches) show hi …
Eligible studies included patients with acute ischemic stroke treated with super-bore aspiration catheters (inner diameter 0.088 in …
Early immune events during SARS-CoV-2 infection impact memory T and B cell responses.
Woloszczuk K, Joyner D, Connors J, Bernui M, Canziani G, Chaiken I, Burger J, van Gils MJ, van Rijswijk J, Olijhoek W, Venkateswaren KV, Venkateswaran N, Bosinger SE, Eckalbar W, Altman MC, van Bakel H, Steen H, Diray-Arce J, Levy O, Maecker HT, Kim-Schulze S, Ozonoff A; IMPACC Network; Sekaly RP, Sanders RW, Kutzler MA, Cairns CB, Fourati S, Haddad EK. Woloszczuk K, et al. Commun Biol. 2026 Jun 5. doi: 10.1038/s42003-026-09927-x. Online ahead of print. Commun Biol. 2026. PMID: 42249109 Free article.
Developmental CA2 perineuronal net reduction restores social memory in Shank3 mutant mice.
Diethorn EJ, Rathaur AB, Ruiz Lopez BR, Eke CK, Gould E. Diethorn EJ, et al. Commun Biol. 2026 Jun 5. doi: 10.1038/s42003-026-10338-1. Online ahead of print. Commun Biol. 2026. PMID: 42249098 Free article.
Individuals with Autism Spectrum Disorder (ASD) and related neurodevelopmental conditions, like Phelan-McDermid syndrome (PMDS), exhibit social recognition deficits. Shank3B knockout (KO) mice, a genetic model with relevance to ASD and PMDS, have deficits in social …
Individuals with Autism Spectrum Disorder (ASD) and related neurodevelopmental conditions, like Phelan-McDermid syndrome (PMDS), exhibit …
Portable biomechanics laboratory enables clinically accessible movement analysis from a handheld smartphone.
Peiffer JD, Shah K, Djuraskovic I, Anarwala S, Abdou K, Patel R, Jayabalan P, Pennicooke B, Cotton RJ. Peiffer JD, et al. NPJ Digit Med. 2026 Jun 5. doi: 10.1038/s41746-026-02825-w. Online ahead of print. NPJ Digit Med. 2026. PMID: 42249074 Free article.

Movement directly reflects neurological and musculoskeletal health, yet objective biomechanical assessment is rarely available in routine care. ...We validate PBL on over 15 hours of data synchronized to ground truth motion capture, finding joint-angle errors < 3

…
Movement directly reflects neurological and musculoskeletal health, yet objective biomechanical assessment is rarely available …
The High-resolution Urban Meteorology for Impacts Dataset for Atlanta Metropolitan Region (HUMID-Atlanta).
Lin TS, Newman AJ, Chang HH, Lane M, O'Lenick CR, Scovronick N, Wilhelmi O, Ebelt S. Lin TS, et al. Sci Data. 2026 Jun 5. doi: 10.1038/s41597-026-07578-5. Online ahead of print. Sci Data. 2026. PMID: 42248935 Free article.
We also compute several common heat exposure indices such as National Weather Service heat index, Humidex index, wet bulb globe temperature index, universal thermal climate index, and apparent temperature. The dataset can be used to estimate population exposure to heat and …
We also compute several common heat exposure indices such as National Weather Service heat index, Humidex index, wet bulb globe tempe …
Evaluating chest-worn light logger adherence: development and application of a wear/non-wear model.
Patterson Gentile C, Thomas A, Shah R, Marquez De Prado B, Raj N, Szperka CL, Aguirre GK. Patterson Gentile C, et al. Sci Rep. 2026 Jun 5. doi: 10.1038/s41598-026-54493-1. Online ahead of print. Sci Rep. 2026. PMID: 42248933 Free article.
Light exposure plays an important role in overall health because it entrains circadian rhythms. Recent technological advances in wearable light loggers allow measurement daily light exposure habits. ...
Light exposure plays an important role in overall health because it entrains circadian rhythms. Recent technological advances in wear …
Genetically diverse CC and DO mouse models enable comprehensive assessments of novel tuberculosis vaccines.
Lai R, Kurtz SL, Gould V, Tran A, Afkhami S, Brosch R, Lindestam Arlehamn CS, Xing Z, Elkins KL, Behar SM. Lai R, et al. NPJ Vaccines. 2026 Jun 5. doi: 10.1038/s41541-026-01498-6. Online ahead of print. NPJ Vaccines. 2026. PMID: 42248881 Free article.
Development of a new vaccine for tuberculosis (TB) to replace the BCG vaccine has been hampered by the lack of a preclinical vaccine model that accurately reflects the genetic heterogeneity of the human population. We previously tested both Collaborative Cross (CC) and Div …
Development of a new vaccine for tuberculosis (TB) to replace the BCG vaccine has been hampered by the lack of a preclinical vaccine model t …
Nasal administration of Protollin enhances monocyte phagocytosis and decreases CD8+ T cell cytotoxicity in subjects with early Alzheimer's disease: a Phase 1 clinical trial.
Kolypetri P, da Silva P, Francisco RS Jr, Frenkel D, Cecere RR, Kiliaan PCJ, Montini F, Saxena S, Clementi WA, Liu X, Sun C, Bergmark RW, Singhal T, Saraceno TJ, Zimmermann J, Gale SA, Selkoe DJ, Chitnis T, Weiner HL. Kolypetri P, et al. NPJ Aging. 2026 Jun 5. doi: 10.1038/s41514-026-00397-3. Online ahead of print. NPJ Aging. 2026. PMID: 42248874 Free article.
Neuroimaging evidence for a dopamine-independent association between motor cortex microstructure and Parkinson's disease severity.
Honhar P, Tinaz S, Ebrahimian Sadabad F, Dias M, Yang Y, Henry S, Hillmer AT, Zakiniaeiz Y, Radhakrishnan R, Comley RA, Zhang X, Hooker BA, Zhang Y, Finnema SJ, Carson RE, Scheinost D, Matuskey D. Honhar P, et al. NPJ Parkinsons Dis. 2026 Jun 5. doi: 10.1038/s41531-026-01411-x. Online ahead of print. NPJ Parkinsons Dis. 2026. PMID: 42248873 Free article.
A chemoproteomic atlas of the human purine interactome for regioselective ligand discovery.
Li Z, Tsai HK, Libby AH, Founds MW, Murtagh OL, Ware ML, Leace DM, Wolfe WJ, Gingrich PW, Al-Lazikani B, Chang CY, Hsu KL. Li Z, et al. Nat Commun. 2026 Jun 5. doi: 10.1038/s41467-026-73407-3. Online ahead of print. Nat Commun. 2026. PMID: 42248851 Free article.
Purines are essential bioactive molecules that interact with a large fraction of the human proteome. Despite their importance, the scope of actionable purine-binding pockets for ligand discovery remains limited. Here, we develop a quantitative chemoproteomics platform usin …
Purines are essential bioactive molecules that interact with a large fraction of the human proteome. Despite their importance, the sc …
D-VRD induction and autologous transplant in patients ≥70 years.
Pasvolsky O, Marcoux C, Milton DR, Tanner MR, Islam MB, Bashir Q, Srour S, Saini N, Lin P, Ramdial J, Nieto Y, Tang G, Aljawai Y, Haider AA, Lee HC, Patel KK, Kebriaei P, Thomas SK, Orlowski RZ, Champlin RE, Shpall EJ, Qazilbash MH. Pasvolsky O, et al. Blood Cancer J. 2026 Jun 5;16(1):91. doi: 10.1038/s41408-026-01522-x. Blood Cancer J. 2026. PMID: 42248841 Free PMC article. No abstract available.
Neighborhood opportunity, white matter, and cognition in a large pediatric neuroimaging study.
Yildiz-Ozhan N, Ku BS, Zekelman LR, Zurrin R, Zhang F, O'Donnell LJ, Rathi Y, Seitz-Holland J, Cetin-Karayumak S. Yildiz-Ozhan N, et al. Transl Psychiatry. 2026 Jun 5. doi: 10.1038/s41398-026-04143-x. Online ahead of print. Transl Psychiatry. 2026. PMID: 42248835 Free article.
Neighborhood opportunity was measured using the Child Opportunity Index 2.0 (COI), which includes an overall score, three domain-level scores capturing Education, Social-Economic, and Health-Environment conditions, and 29 individual neighborhood indicators. ...At th …
Neighborhood opportunity was measured using the Child Opportunity Index 2.0 (COI), which includes an overall score, three domain-level score …
Prenatal Diagnosis and Novel Therapeutics in Treatment of Genetic Conditions: Challenges and Opportunities.
Talati AN, Jones M, Hardisty EE, Michie M, Allyse MA, Vora NL. Talati AN, et al. Clin Ther. 2026 Jun 5:S0149-2918(26)00182-7. doi: 10.1016/j.clinthera.2026.05.019. Online ahead of print. Clin Ther. 2026. PMID: 42248756
Therapeutic options for genetic conditions are rapidly expanding, including options for immediate postnatal therapy or in utero therapy. Many patient- and health care system-related factors influence access to and success of these therapies. ...Second, we will review exist …
Therapeutic options for genetic conditions are rapidly expanding, including options for immediate postnatal therapy or in utero therapy. Man …
Rethinking endoleaks: is it time to change the name?
Lyden SP, Brooke BS, Khaja MS, Caputo FJ, Schneider DB, Morgan RA, Zettervall SL, Hamady M, Tran K, Deaton D, Beck AW, Schiro BJ, Stern JR, Angle JF, Abel DB. Lyden SP, et al. J Vasc Surg. 2026 Jul;84(1):1-3. doi: 10.1016/j.jvs.2026.03.005. J Vasc Surg. 2026. PMID: 42248620 No abstract available.
CD19/CD22 bivalent CAR T cells in children, adolescents and young adults with B-ALL: final phase 1 trial results.
Silbert SK, Gava F, Yates B, Rankin AW, Rocco JM, Shao L, Dreyzin A, Cai Y, Lamplugh C, Han KL, Prochazkova M, Little L, Foley T, Sankaran H, Martin K, Garces P, Jin P, Chien CD, Taylor N, Fry TJ, Yuan CM, Wang HW, Stroncek DF, Highfill SL, Shalabi H, Shah NN. Silbert SK, et al. J Immunother Cancer. 2026 Jun 5;14(6):e015296. doi: 10.1136/jitc-2026-015296. J Immunother Cancer. 2026. PMID: 42248607 Free article.
Rheumatoid arthritis-associated interstitial lung disease: screening, diagnosis, and treatment-an expert group consensus statement.
Solomon JJ, Dieudé P, Matson SM, Lee JS, Rojas-Serrano J, Sebastiani M, Gonzalez A, Demoruelle MK, Hoffman-Vold AM, Kam MLW, Swigris JJ, Sparks JA, Brown KK, Cottin V, Kellermeyer LM, Wilson KC, Waseda Y, Crestani B, Walsh SLF, Poletti V, Doyle T, Koduri G, Kelly C, Danoff S, Dellaripa PF. Solomon JJ, et al. Lancet Respir Med. 2026 Jun 5:S2213-2600(26)00094-9. doi: 10.1016/S2213-2600(26)00094-9. Online ahead of print. Lancet Respir Med. 2026. PMID: 42248165 Review.
Inhibiting glycan degradation prevents HIV-induced inflammaging and cognitive impairment.
Giron LB, Borjabad A, Hadas E, Granche J, Marques de Menezes EG, Premeaux TA, He H, Yeung ST, Singh S, Friday C, Glover J, Balboa E, Dopkin D, Burrows M, Secreto A, Skuli N, Tateno H, Denton PW, Palella F, Corley MJ, Ndhlovu LC, Norris PJ, Tassiopoulos K, Volsky DJ, Abdel-Mohsen M. Giron LB, et al. Med. 2026 Jun 5:101175. doi: 10.1016/j.medj.2026.101175. Online ahead of print. Med. 2026. PMID: 42248145
FUNDING: This study was funded by the National Institutes of Health (NIH)....
FUNDING: This study was funded by the National Institutes of Health (NIH)....
Priorities for psychedelic research among people who use psychedelics.
Kruger DJ, Czerew A, Farquhar L, Redfield J, Swaroop V, Andrews T, Colvard B, Faqqouseh M, Barron J, Herberholz M, Glynos NG, Boehnke KF. Kruger DJ, et al. J Psychiatr Res. 2026 Jun 2;201:1-6. doi: 10.1016/j.jpsychires.2026.06.007. Online ahead of print. J Psychiatr Res. 2026. PMID: 42248136
This study aimed to identify these priorities through an anonymous online survey conducted in 2022 among U.S. adults who self-reported past psychedelic use. A trained team coded the responses of 1192 participants to an open-ended question regarding their views on th …
This study aimed to identify these priorities through an anonymous online survey conducted in 2022 among U.S. adults who self- …
Nitric oxide-driven Warburg reprogramming at the NOS2-COX2 axis: An integrative engine of cancer hallmarks.
Coutinho LL, Palmieri EM, Ridnour LA, Cheng RYS, Heinz WF, Anderson SK, Billiar TR, Chang J, Lockett SJ, Rangel MC, Thomas DD, McVicar DW, Wink DA. Coutinho LL, et al. Redox Biol. 2026 Jun 2;95:104245. doi: 10.1016/j.redox.2026.104245. Online ahead of print. Redox Biol. 2026. PMID: 42248132 Free article. Review.
Early work in macrophages established NOS2-derived NO as both a signaling molecule and metabolic stressor that inhibits oxidative phosphorylation (OXPHOS) by targeting iron-sulfur enzymes and respiratory complexes, forcing neighboring cells to rewire metabolism. In human t …
Early work in macrophages established NOS2-derived NO as both a signaling molecule and metabolic stressor that inhibits oxidative phosphoryl …
Response to: Commentary on "Long-term treatment with esketamine nasal spray in patients with treatment resistant depression: Results from the ESCAPE-LTE study".
Reif A, Anıl Yağcıoğlu AE, Bitter I, Buyze J, Frey R, Fu DJ, Godinov Y, Haggström L, Kambarov Y, Nielsen RE, Oliveira-Maia AJ, von Holt C, Young AH, Cubała WJ. Reif A, et al. Eur Neuropsychopharmacol. 2026 Jun 5;112:112885. doi: 10.1016/j.euroneuro.2026.112885. Online ahead of print. Eur Neuropsychopharmacol. 2026. PMID: 42247854 No abstract available.
Enhanced recovery after surgery (ERAS®) society guidelines for gynecologic oncology: 2026 update.
Nelson G, Altman AD, Metcalfe A, Fotopoulou C, Taylor J, Glaser G, Bakkum-Gamez J, Kumar A, Meyer LA, Stone R, Mena G, Elias KM, Bisch SP, Zivanovic O, Miralpeix E, Bhandoria G, Eriksson AGZ, Ruzycki SM, Sultan P, Sauro KM, Blake L, Brindle ME, Ramirez PT, Dowdy SC. Nelson G, et al. Gynecol Oncol. 2026 Jun 5;210:153-173. doi: 10.1016/j.ygyno.2026.05.022. Online ahead of print. Gynecol Oncol. 2026. PMID: 42247726 Review.
A similarity metric, rubric, and unified hierarchy for biomedical publication types and study designs.
Smalheiser NR, Menke JD, Holt AW. Smalheiser NR, et al. Database (Oxford). 2026 Jan 15;2026:baag022. doi: 10.1093/database/baag022. Database (Oxford). 2026. PMID: 42247591 Free PMC article.
The PT rubric provides an overview that complements the existing NIH MeSH Hierarchy trees, and the unified hierarchy permits proper automated expansion for PT indexing and PubMed user queries involving PT terms....
The PT rubric provides an overview that complements the existing NIH MeSH Hierarchy trees, and the unified hierarchy permits proper a …
Covalent inhibitors of human papillomavirus type 16 E6 protein restore p53 function and suppress growth of HPV-driven tumors in vivo.
Rietz A, Kumari L, Koirala A, Pelletier S, Lu Z, Androphy EJ. Rietz A, et al. Proc Natl Acad Sci U S A. 2026 Jun 9;123(23):e2606213123. doi: 10.1073/pnas.2606213123. Epub 2026 Jun 5. Proc Natl Acad Sci U S A. 2026. PMID: 42247559
High-risk human papillomaviruses (HPVs) promote malignant progression through sustained expression of the viral oncoprotein E6, which drives degradation of the tumor suppressor p53 and creates an oncogenic dependency in HPV-positive cancers. ...
High-risk human papillomaviruses (HPVs) promote malignant progression through sustained expression of the viral oncoprotein E6, which …
Problematic internet use and borderline personality features: A systematic review informed by the alternative model of personality disorders.
Chesivoir E, Hernandez E, Dolan S. Chesivoir E, et al. J Behav Addict. 2026 Jun 4:2006.2025.00590. doi: 10.1556/2006.2025.00590. Online ahead of print. J Behav Addict. 2026. PMID: 42247264 Review.
This review synthesizes these approaches using the Alternative Model of Personality Disorders (AMPD), examining how BPD-relevant pathological personality traits (Criterion B) and impairments in self and interpersonal functioning (Criterion A) relate to PIU. ...Study qualit …
This review synthesizes these approaches using the Alternative Model of Personality Disorders (AMPD), examining how BPD-relevant path …
Maternal Respiratory Syncytial Virus Prefusion F Vaccination and Acute Respiratory Illness in Infants.
Rick AM, Deese J, Kerr JE, Hui J, Liu H, Yu G, Chang CH, Fazio N, Tahir MH, Bieltz R, Ravindra A, Megli C, Jeyabalan A, Pugh SJ, Patel D, Fan R, Atwell JE, Cané A, Martin JM. Rick AM, et al. JAMA Netw Open. 2026 Jun 1;9(6):e2616773. doi: 10.1001/jamanetworkopen.2026.16773. JAMA Netw Open. 2026. PMID: 42247233 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: This retrospective case-control study (Effectiveness of ABRYSVO Maternal Respiratory Syncytial Virus Vaccine Against RSV in Infants in Western Pennsylvania study) using a test-negative design was conducted within a single health system in …
DESIGN, SETTING, AND PARTICIPANTS: This retrospective case-control study (Effectiveness of ABRYSVO Maternal Respiratory Syncytial Virus Vacc …
Patient Experiences With GLP-1 Receptor Agonists.
de Vere Hunt I, Ramirez-Posada M, Babu CS, Brown-Johnson C, Linos E, Rodriguez F. de Vere Hunt I, et al. JAMA Netw Open. 2026 Jun 1;9(6):e2616951. doi: 10.1001/jamanetworkopen.2026.16951. JAMA Netw Open. 2026. PMID: 42247231 Free PMC article.
Few scientific publications have reported patients' experiences of taking GLP-1 RAs in a variety of health contexts outside its use as treatment for type 2 diabetes. OBJECTIVE: To provide insight into the lived experiences of patients taking GLP-1 RAs to inform optimal lon …
Few scientific publications have reported patients' experiences of taking GLP-1 RAs in a variety of health contexts outside its use a …
A Multiregional Decentralized Clinical Trial Program to Improve Access.
Haddad TC, Mercado LA, Le-Rademacher JG, Enarson DA, Sener U, Kumar A, Price KA, Juhn YJ, Cartin-Ceba R, Colon-Otero G, Willman CL, Garovic VD, Kottschade RS. Haddad TC, et al. JAMA Netw Open. 2026 Jun 1;9(6):e2617204. doi: 10.1001/jamanetworkopen.2026.17204. JAMA Netw Open. 2026. PMID: 42247228 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: This descriptive quality improvement study was conducted from January 2024 to March 2025 at Mayo Clinic, a US multiregional, academic medical center (AMC) comprising 3 sites and an affiliated, community-based health care system. All indiv …
DESIGN, SETTING, AND PARTICIPANTS: This descriptive quality improvement study was conducted from January 2024 to March 2025 at Mayo Clinic, …
Health-related quality of life in older survivors of melanoma: a SEER-MHOS study.
Shan DM, Irwin L, Allaire BT, Mochel MC, Maher ME, Jensen RE. Shan DM, et al. Qual Life Res. 2026 Jun 5;35(7):162. doi: 10.1007/s11136-026-04259-z. Qual Life Res. 2026. PMID: 42247192 Free PMC article.
Given increasing melanoma survivorship in recent years, there is a need to describe and quantify HRQOL outcomes in a U.S. population-based sample of melanoma cancer survivors. This study aims to characterize HRQOL in melanoma survivors based on stage of diagnosis, d …
Given increasing melanoma survivorship in recent years, there is a need to describe and quantify HRQOL outcomes in a U.S. popu …
Bitter taste TAS2R14 and TAS2R46 receptors bound to G proteins: comparison of cryo-EM, AlphaFold, and molecular dynamics structures.
Pachter R, Kim SK, Xu YC, Liu G, Kim S, Goddard WA. Pachter R, et al. Eur Biophys J. 2026 Jun 5. doi: 10.1007/s00249-026-01841-8. Online ahead of print. Eur Biophys J. 2026. PMID: 42247183
Bitter taste type 2 G protein-coupled receptors (TAS2R GPCRs) detect bitter substances on the tongue, but they are also prevalent in tissues throughout the human body that play a role in cancer and other diseases, making them targets for pharmacological research. ...
Bitter taste type 2 G protein-coupled receptors (TAS2R GPCRs) detect bitter substances on the tongue, but they are also prevalent in tissues …
Diabetes-associated MYT1 and ST18 genes regulate human beta cell insulin secretion and survival via other diabetes risk genes.
Hu R, Hamilton N, Wang Y, Tong X, Yagan M, Dadi PK, Harmelink C, Doss TD, Liu J, Xu Y, Simmons AJ, Lau KS, Stein R, Balamurugan AN, Kaverina I, Coate KC, Jacobson DA, Liu Q, Gu G. Hu R, et al. Diabetologia. 2026 Jun 5. doi: 10.1007/s00125-026-06757-8. Online ahead of print. Diabetologia. 2026. PMID: 42247169
Based on our previous findings that the family of myelin transcription factors (MYT TFs; including MYT1, MYT1L and ST18) prevents mouse beta cell failure by repressing the overactivation of stress response, their regulation by obesity-related nutrition signals in human bet …
Based on our previous findings that the family of myelin transcription factors (MYT TFs; including MYT1, MYT1L and ST18) prevents mouse beta …
Thoughts of Death or Self-injury, Non-same-day ART Initiation, and 2-year Incidence of Disengagement from Care Among People Entering HIV Care in Cameroon.
Filiatreau LM, Rana Magar J, Ebasone PV, Shields M, Dzudie A, Yotebieng M, Wainberg M, Parcesepe AM. Filiatreau LM, et al. AIDS Behav. 2026 Jun 5. doi: 10.1007/s10461-026-05149-8. Online ahead of print. AIDS Behav. 2026. PMID: 42247071
As strong predictors of suicidal ideation and death by suicide, it is paramount to understand these risk indicators, particularly in populations with heightened susceptibility to poor mental health. We aimed to characterize thoughts of death or self-injury (i.e., self-inju …
As strong predictors of suicidal ideation and death by suicide, it is paramount to understand these risk indicators, particularly in populat …
Development of the Surgical Implantation and Fixation of an Implanted Middle Ear Microphone, the "UmboMic," in Cadaveric Sheep.
Comens IC, Zhou C, Nguyen DL, Wawrzynek EF, Zhang JZ, Kymissis I, Welling DB, Lang JH, Nakajima HH, Olson ES. Comens IC, et al. J Assoc Res Otolaryngol. 2026 Jun 5. doi: 10.1007/s10162-026-01056-w. Online ahead of print. J Assoc Res Otolaryngol. 2026. PMID: 42247024
CONCLUSION: When implanted in sheep cadaveric ears, UmboMic performance was similar to previous measurements in fresh human cadaveric temporal bones. The method of simulating surgical drilling using micro-CT and simple open-source software is economical and broadly applica …
CONCLUSION: When implanted in sheep cadaveric ears, UmboMic performance was similar to previous measurements in fresh human cadaveric …
Donor-Derived Cell-Free DNA as a Prognostic Biomarker After Heart Transplantation: The DEFINE-HT Study.
Shah P, Kim PJ, Schlendorf KH, Baran DA, Colvin MM, DeVore AD, Eisen HJ, Ghafourian K, Givertz MM, Hsich E, Kennedy JLW, Kransdorf EP, Nativi-Nicolau JN, Patel J, Tseliou E, Wever-Pinzon O, Doud A, Bloom MS, Carey SA, Kaur N, Biagini DG, Marshall KE, Olympios M, Mehra MR, Stehlik J. Shah P, et al. JACC Heart Fail. 2026 Jun 3:103152. doi: 10.1016/j.jchf.2026.103152. Online ahead of print. JACC Heart Fail. 2026. PMID: 42246920
METHODS: The DEFINE-HT (Development of Noninvasive Cell-free DNA to Supplant Invasive Biopsy in Heart Transplantation) was a prospective, observational study following adult HT recipients at 10 U.S. centers for 1-year post-HT; blood was collected for dd-cfDNA testin …
METHODS: The DEFINE-HT (Development of Noninvasive Cell-free DNA to Supplant Invasive Biopsy in Heart Transplantation) was a prospective, ob …
[Evaluation of the efficiency of combined neuroprotection and high-intensity magnetotherapy in the medical rehabilitation of patients with ischemic stroke].
Butko DY, Davydov AT, Koneva ES, Lyadov KV, Okhotnikova AA, Reutsky IA, Shcheglova MA, Yakovlev EV. Butko DY, et al. Zh Nevrol Psikhiatr Im S S Korsakova. 2026;126(5):88-94. doi: 10.17116/jnevro202612605188. Zh Nevrol Psikhiatr Im S S Korsakova. 2026. PMID: 42246531 Russian.
Treatment effectiveness was evaluated based on clinical and neurological metrics, cognitive function assessments, electroencephalography data, ultrasound dopplerography (USDG) of cervical and cranial vessels, and neuropsychological testing administered on days 14 and 21 po …
Treatment effectiveness was evaluated based on clinical and neurological metrics, cognitive function assessments, electroencephalogra …
Mandatory Reporting: What's the Empirical Evidence Base? A Systematic Scoping Review.
Black CFD, Phillips C, Sanders IA, Sajjad SA. Black CFD, et al. Child Maltreat. 2026 Jun 5:10775595261448548. doi: 10.1177/10775595261448548. Online ahead of print. Child Maltreat. 2026. PMID: 42246472 Review.
This scoping review applied concepts from the NIH Stage Model to map and organize five decades of research on MR, focusing on research methodology, to highlight the strength of causal evidence at each stage of research. ...Studies classified as Stage III: Real World Effica …
This scoping review applied concepts from the NIH Stage Model to map and organize five decades of research on MR, focusing on researc …
Finerenone in Patients With Chronic Kidney Disease Due to Glomerular Diseases: A Randomized Clinical Trial.
Neuen BL, Perkovic V, Agarwal R, Cherney DZI, Lam CSP, Wanner C, Tuttle KR, Sarafidis P, Barratt J, Burgner A, Chen X, Chew-Wong A, Dobronravov VA, Floege J, McCafferty K, Nangaku M, Packham D, Papachristou E, Pergola PE, Speeckaert MM, Subbiah A, Tang SCW, Tang S, Yeo SC, Jongs N, Smeijer JD, Berger M, Brinker M, Dayoub R, Elliott J, Li N, Mueller K, Rethemeier N, Finkelsztein MY, Heerspink HJL; FIND-CKD Investigators. Neuen BL, et al. JAMA. 2026 Jun 5:e269923. doi: 10.1001/jama.2026.9923. Online ahead of print. JAMA. 2026. PMID: 42246414
RNA-binding proteins in cell adhesion at a glance.
Rekad Z, Mili S, Van Obberghen-Schilling E, Ciais D. Rekad Z, et al. J Cell Sci. 2026 Jun 1;139(11):jcs264689. doi: 10.1242/jcs.264689. Epub 2026 Jun 5. J Cell Sci. 2026. PMID: 42246342 Review.
The NTR/prodrug revolution: Tools for controlling cell loss and regeneration.
Kim GJ, Parsons M. Kim GJ, et al. Elife. 2026 Jun 5;15:RP110593. doi: 10.7554/eLife.110593. Elife. 2026. PMID: 42246187 Free PMC article.
This review highlights how the NTR system has been deployed to model a spectrum of human diseases, including Parkinson's disease, retinal degeneration, demyelinating disorders, and kidney disease. ...These best practices will allow the researcher to develop a precis …
This review highlights how the NTR system has been deployed to model a spectrum of human diseases, including Parkinson's disease, ret …
Blue Light Exposure During Sleep in Type 1 Diabetes: Impacts on Glycemic Control and Psychosocial Health.
Hong SJ, Pratuangtham S, Martyn-Nemeth P, Steffen AD, Park CG, Reutrakul S. Hong SJ, et al. J Sleep Res. 2026 Jun 5:e70380. doi: 10.1111/jsr.70380. Online ahead of print. J Sleep Res. 2026. PMID: 42246173
Light exposure at night is linked to increased risk for obesity and insulin resistance in the general population. While sleep health is recognized as a key component of diabetes management, there has been less emphasis on nighttime light exposure. ...
Light exposure at night is linked to increased risk for obesity and insulin resistance in the general population. While sleep health …
Educational Background and Demographic Characteristics of Anesthesiology Department Chairs in the United States.
Estright AW, Pruitt KA, Pope SE, Childers M, Clark SC, Singh M, Alter JA, Hill HE, Tollinche LE. Estright AW, et al. Anesthesiol Open. 2026 Jun 1;1(2):e0017. doi: 10.1097/ao9.0000000000000017. eCollection 2026 Jul. Anesthesiol Open. 2026. PMID: 42245980 Free PMC article.
Academic anesthesiology department chairs face significant responsibilities, yet formal leadership pathways remain unclear. The purpose of this study was to characterize the educational backgrounds and career trajectories of current U.S. anesthesiology dep …
Academic anesthesiology department chairs face significant responsibilities, yet formal leadership pathways remain unclear. The purpo …
Informing Scalable Implementation Strategies for Returning Individual Research Results: A Mixed-Methods Study Across Multisite Research Teams.
Kent D, Villegas-Downs M, Pasquinelli M, Arcia A, Greene L, Darski S, Sugar E, Kalhan R, Srikantha S, Musick H, Krishnan J, Gerald L. Kent D, et al. Res Sq [Preprint]. 2026 May 25:rs.3.rs-9621011. doi: 10.21203/rs.3.rs-9621011/v1. Res Sq. 2026. PMID: 42245816 Free PMC article. Preprint.
Introduction : Despite growing national guidance supporting the return of individual research results (IRRs) to participants, scalable, theory-informed implementation strategies to support consistent and effective return across multi-site studies remain underdeveloped. ... …
Introduction : Despite growing national guidance supporting the return of individual research results (IRRs) to participants, scalabl …
Air-liquid interface-centered oxygen engineering in human brain organoids: intact, sliced, and microfluidic extensions.
Vijakumaran U, Anjum A, Devaraju P, Abd Razak NH, Daud MF, Mohd Idris I. Vijakumaran U, et al. Front Cell Dev Biol. 2026 May 20;14:1809928. doi: 10.3389/fcell.2026.1809928. eCollection 2026. Front Cell Dev Biol. 2026. PMID: 42245485 Free PMC article. Review.
Brain organoids have become essential in vitro models for investigating human brain development, function, and disease, including both unguided cerebral organoids and guided region-specific neural models. ...By comparing the advantages and limitations of ALI-based systems, …
Brain organoids have become essential in vitro models for investigating human brain development, function, and disease, including bot …
A Multisite, Randomized Trial Testing a Community-Digital Health Intervention among Black and Latino Adults with Cardiometabolic Conditions: The Roots of Wellness (Raices del Bienestar) Protocol.
Himmelfarb CR, Chepkorir J, Miller HN, Ogungbe O, Perrin N, Olawole W, Cain G, Kinlock BL, Mullins CD, Kutcherman I, Barger P, Diaz-Ramirez M, Rodriguez J, Trujillo R, González-Salinas A, Clark R, Andrade EL. Himmelfarb CR, et al. medRxiv [Preprint]. 2026 May 27:2026.05.26.26354175. doi: 10.64898/2026.05.26.26354175. medRxiv. 2026. PMID: 42245006 Free PMC article. Preprint.
BACKGROUND: Black and Latino adults in the United States experience a disproportionate burden of cardiometabolic conditions due to interacting behavioral, social, and structural drivers of health. Less is known about the impact of integrating digital health t …
BACKGROUND: Black and Latino adults in the United States experience a disproportionate burden of cardiometabolic conditions due to interacti …
Daily Parental Positive Experiences Are Linked to Better Daily Parenting Practice Through Reduced Stress and Depressive Mood.
Yu D, Deleon J, Dobson M, Watrous JNH, Morris AS, Hays-Grudo J. Yu D, et al. Fam Process. 2026 Jun;65(2):e70166. doi: 10.1111/famp.70166. Fam Process. 2026. PMID: 42244489
Studies have found that parents' cumulative protective and compensatory experiences (PACEs) can protect parenting quality from stress and mental health issues and promote positive parenting through elevated mental health. Existing studies have focused primarily on b …
Studies have found that parents' cumulative protective and compensatory experiences (PACEs) can protect parenting quality from stress and me …
Inflammation Associated With Obesity, Aging, and Amyloid Burden in Adults With Down Syndrome.
Fleming-Batayneh VL, Helsel BC, Ptomey LT, Handen BL, Mapstone M, Petersen M, Krinsky-McHale SJ, Hom CL, Minhas D, Luo W, Laymon C, Lee JH, Cohen A, Ances BM, Brickman AM, Pulsifer M, Rosas HD, Lai F, Zaman SH, Head E, Tudorascu D, Price J, Schmitt F, Christian BT, Okonkwo O, Hartley SL; Alzheimer Biomarkers Consortium‐Down Syndrome (ABC‐DS) Investigators. Fleming-Batayneh VL, et al. Obesity (Silver Spring). 2026 Jun 5. doi: 10.1002/oby.70229. Online ahead of print. Obesity (Silver Spring). 2026. PMID: 42244445
Site- and age-dependent associations between Fusobacterium nucleatum and colorectal cancer mortality.
Loroña NC, LaBrie S, Thomas CE, Yin H, Huyghe JR, Qu C, Thomas S, Nayemi S, Ammar H, Kahsai O, Hsu L, Curtis KR, Koehne A, Redwood DG, Li L, Li CI, Peters U, Thomas TK, Phipps AI, Figueiredo JC, Hullar M. Loroña NC, et al. Cancer. 2026 Jun 15;132(12):e70484. doi: 10.1002/cncr.70484. Cancer. 2026. PMID: 42244408
BACKGROUND: Fusobacterium nucleatum (Fn) is a bacterium typically found in the human oral cavity that has been implicated in the development and progression of colorectal cancer (CRC). ...
BACKGROUND: Fusobacterium nucleatum (Fn) is a bacterium typically found in the human oral cavity that has been implicated in the deve …
Structures of nickel-, copper-, and zinc-salophen derivatives.
Seymour DA Jr, Amsbaugh RV, Colcord CG, Fejes IR, Gebhardt LC, Yap GPA, Deegan MM. Seymour DA Jr, et al. Acta Crystallogr C Struct Chem. 2026 Jul 1. doi: 10.1107/S2053229626005450. Online ahead of print. Acta Crystallogr C Struct Chem. 2026. PMID: 42244386
Exposure Pattern Determines Methamphetamine-Induced Right Ventricular Dysfunction and Vascular Remodeling.
Kumar A, Mahajan A, Krishnamachary B, Chen L, Dhillon NK. Kumar A, et al. Compr Physiol. 2026 Jun;16(3):e70191. doi: 10.1002/cph4.70191. Compr Physiol. 2026. PMID: 42244047 Free PMC article.
This study aimed to develop a rat model of MA-PAH that reflects human patterns of MA abuse. Male Wistar rats received methamphetamine (MA, 5 mg/kg, i.p.) for 8 weeks using either a chronic daily regimen or a binge-and-crash regimen. ...
This study aimed to develop a rat model of MA-PAH that reflects human patterns of MA abuse. Male Wistar rats received methamphetamine …
Air pollution and disease progression among patients with primary glomerular disease: an expanded study with extended follow-up.
Troost JP, Kshirsagar AV, Smoyer WE, Klein J, Merchant ML, Helmuth M, Mariani LH, Kretzler M, Smith AR, Lacey F, Engel LS, Trachtman H, O'Lenick CR. Troost JP, et al. Environ Health. 2026 Jun 5. doi: 10.1186/s12940-026-01312-9. Online ahead of print. Environ Health. 2026. PMID: 42243965 Free article.
BACKGROUND: Air pollution is increasingly recognized as a risk factor for progression of kidney disease; however, few studies have examined its impact among patients with primary glomerular disorders. To address this knowledge gap, we previously reported positive associati …
BACKGROUND: Air pollution is increasingly recognized as a risk factor for progression of kidney disease; however, few studies have examined …
"Chill packs" self-administered olanzapine as psychiatric harm reduction for methamphetamine-induced psychosis: a narrative review of the existing evidence base.
Ruedisueli I, Marienfeld C, Tiefenthaler C, Lee A, Harvey-Vera A, Strathdee S, Friedman JR. Ruedisueli I, et al. Harm Reduct J. 2026 Jun 4. doi: 10.1186/s12954-026-01475-1. Online ahead of print. Harm Reduct J. 2026. PMID: 42243786 Free article. Review.
One recent study assessed the effectiveness of an implementation of chill packs by the San Francisco Department of Health and found that repeat psychiatric emergency visits dropped by 32% after two-months and 13% after six-months from receipt of a chill pack. ...
One recent study assessed the effectiveness of an implementation of chill packs by the San Francisco Department of Health and …
Demographic patterns among physician assistant/associate applicants and matriculants compared with U.S. population benchmarks, 2013-2022.
Kibe LW, Schrode KM. Kibe LW, et al. BMC Med Educ. 2026 Jun 4. doi: 10.1186/s12909-026-09588-8. Online ahead of print. BMC Med Educ. 2026. PMID: 42243752 Free article.
However, as of 2025, the PA workforce does not mirror the present and projected changes in the U.S. demographic composition. We examine nine-year race, ethnic, and gender trends of PA training programs- the pipeline to the profession. ...CONCLUSIONS: For the last te …
However, as of 2025, the PA workforce does not mirror the present and projected changes in the U.S. demographic composition. W …
SeqBoard: a genomics-based data dashboard for comprehensive wastewater virome monitoring.
Bauer C, Reger N, Rustem HAL, Tisza M, Triosi CL, Javornik Cregeen S, Ghobrial L, Gitter A, Wu F, Surathu A, Deegan J, Mena KD, Petrosino J, Boerwinkle E, Hanson BM, Maresso AW. Bauer C, et al. J Am Med Inform Assoc. 2026 Jun 5:ocag088. doi: 10.1093/jamia/ocag088. Online ahead of print. J Am Med Inform Assoc. 2026. PMID: 42243631
OBJECTIVES: To develop the first public-facing dashboard that translates genomic sequencing data from wastewater into accessible and actionable community information concerning human pathogenic viruses, representing a shift to sequencing-based public health wastewat …
OBJECTIVES: To develop the first public-facing dashboard that translates genomic sequencing data from wastewater into accessible and actiona …
Documented follow-up to memory concerns reported at the Medicare Annual Wellness Visit.
Wec A, Wu M, Scerpella D, Zhang Z, Peereboom D, Colburn JL, Nothelle SK, Green AR, Wolff JL, Powell DS. Wec A, et al. Alzheimers Dement. 2026 Jun;22(6):e71576. doi: 10.1002/alz.71576. Alzheimers Dement. 2026. PMID: 42243620 Free PMC article.
METHODS: We use electronic medical record (EMR) data from an academic health system to examine EMR-documented follow-up actions for patients with newly reported memory concerns on the AWV health risk assessment, including formal cognitive assessment or specialist re …
METHODS: We use electronic medical record (EMR) data from an academic health system to examine EMR-documented follow-up actions for p …
Classic Psychedelics for Chronic Pain: A Critical Review of the Literature and Practical Advice for Clinicians.
Boehnke KF, Pouyan N, Aday JS. Boehnke KF, et al. Drugs. 2026 Jun 4. doi: 10.1007/s40265-026-02339-5. Online ahead of print. Drugs. 2026. PMID: 42243569 Review.
In parallel with growing dissatisfaction with conventional therapies, classic serotonergic psychedelics, such as psilocybin, lysergic acid diethylamide (LSD), ayahuasca, N,N-dimethyltryptamine (DMT), and mescaline, administered alone or within psychedelic-assisted therapy models, …
In parallel with growing dissatisfaction with conventional therapies, classic serotonergic psychedelics, such as psilocybin, lysergic acid d …
Spinal cord stimulation for upper limb motor function in people with chronic post-stroke hemiparesis: a feasibility trial.
de Freitas RM, Bhatia S, Sorensen E, Verma N, Carranza E, Ensel S, Borda L, Boos A, Goldsmith J, Fisher LE, Fields DP, Powell MP, Gordon S, Balzer J, Friedlander RM, Wittenberg GF, Gerszten PC, Krakauer JW, Pirondini E, Weber DJ, Capogrosso M. de Freitas RM, et al. Nat Med. 2026 Jun 4. doi: 10.1038/s41591-026-04435-1. Online ahead of print. Nat Med. 2026. PMID: 42243548
Chronic arm and hand hemiparesis is a major cause of disability after stroke. Unfortunately, standard-of-care rehabilitation falls well short of the high doses required to experience improvements. ...These findings provide preliminary evidence of the safety, feasibility an …
Chronic arm and hand hemiparesis is a major cause of disability after stroke. Unfortunately, standard-of-care rehabilitation falls we …
Patient-specific modeling identifies metabolic interventions for reversing glucose use reprogramming in alcohol-associated hepatitis.
Manchel A, Mahadevan R, Hoek JB, Bataller R, Vadigepalli R. Manchel A, et al. Commun Biol. 2026 Jun 4. doi: 10.1038/s42003-026-10407-5. Online ahead of print. Commun Biol. 2026. PMID: 42243508 Free article.
We develop 89 personalized genome-scale metabolic models by integrating a generic human cellular metabolic model with liver transcriptomics data from AH patients with varying disease severity and healthy controls. ...
We develop 89 personalized genome-scale metabolic models by integrating a generic human cellular metabolic model with liver transcrip …
Diverse anelloviruses identified in wild geladas (Theropithecus gelada).
Saroff MJ, Kraberger S, Olivo D, Lemma A, Ayele F, Abebe B, Kebede F, Chiou KL, Snyder-Mackler N, Schneider-Crease IA, Varsani A. Saroff MJ, et al. Arch Virol. 2026 Jun 4;171(7):199. doi: 10.1007/s00705-026-06651-z. Arch Virol. 2026. PMID: 42243375
Anelloviruses are circular single stranded DNA viruses that are highly prevalent among humans and other mammal and avian hosts, with persistent infections enduring throughout the lifespan without causing disease. Investigating these viruses in non-human primate hosts can o …
Anelloviruses are circular single stranded DNA viruses that are highly prevalent among humans and other mammal and avian hosts, with persist …
Urban ambient air pollution and blood pressure in schoolchildren in Accra, Ghana.
Alli AS, Kyeremateng KA, Nimo J, Lange CL, Dery N, Anku P, Adzrakor LY, Kotoka GK, Oppong P, Agyei-Mensah S, Oulhote Y, Hughes AF, Ezzati M, Arku RE. Alli AS, et al. Sci Rep. 2026 Jun 4. doi: 10.1038/s41598-026-54135-6. Online ahead of print. Sci Rep. 2026. PMID: 42243366 Free article.
We performed a cross-sectional analysis among 919 (60% girls) schoolchildren aged 7-14 years across 90 elementary schools. Following NIH guideline, we define elevated BP as age, sex, and height specific systolic and/or diastolic BP values at 90th percentile. ...Children' …
We performed a cross-sectional analysis among 919 (60% girls) schoolchildren aged 7-14 years across 90 elementary schools. Following NIH …
Effects of Multilevel and Multidomain Interventions on Glycemic Control Among Black Persons with Type 2 Diabetes in the U.S.: A Systematic Review and Meta-Analysis.
Osman F, Jiang C, Deckard AN, Staab EM, Thomas NC, Wan W, Peek ME, Alexander JT, Laiteerapong N. Osman F, et al. J Racial Ethn Health Disparities. 2026 Jun 4. doi: 10.1007/s40615-026-03035-6. Online ahead of print. J Racial Ethn Health Disparities. 2026. PMID: 42243353 Review.
BACKGROUND: Type 2 diabetes (T2D) disproportionately affects Black individuals in the U.S., who have higher rates of complications and worse glycemic control. This systematic review and meta-analysis evaluated the effectiveness of non-pharmacological interventions o …
BACKGROUND: Type 2 diabetes (T2D) disproportionately affects Black individuals in the U.S., who have higher rates of complicat …
Estradiol modulated brain connectivity in females during midlife performing an episodic memory task.
Testo AA, Dumas JA. Testo AA, et al. Brain Imaging Behav. 2026 Jun 5;20(3):98. doi: 10.1007/s11682-026-01167-1. Brain Imaging Behav. 2026. PMID: 42243347 Free PMC article.
We assessed the relationship between estradiol level and task-modulated effective connectivity between brain regions during an episodic memory task in females during midlife. We utilized data from the Human Connectome Project - Aging 2.0 release. One hundred and fifty fema …
We assessed the relationship between estradiol level and task-modulated effective connectivity between brain regions during an episodic memo …
High resolution ES-DMA quantifies AAV capsid DNA content by electrical mobility to mass correlation.
Dennett P, Young LM, Draper BE, Schmitt J, Jarrold M, Perez-Lorenzo LJ. Dennett P, et al. Gene Ther. 2026 Jun 4. doi: 10.1038/s41434-026-00626-0. Online ahead of print. Gene Ther. 2026. PMID: 42243319
These impurities contribute to high production costs and reduced therapeutic efficacy, resulting in higher required doses and increased risks to patient health. Here we present high-resolution electrospray differential mobility analysis (ES-DMA) as a novel benchtop analyti …
These impurities contribute to high production costs and reduced therapeutic efficacy, resulting in higher required doses and increased risk …
Structural insights into predicted protein-protein interactions and protein complexes in the human proteome.
Pei J, Zhang J, Cong Q. Pei J, et al. Sci Rep. 2026 Jun 4. doi: 10.1038/s41598-026-54567-0. Online ahead of print. Sci Rep. 2026. PMID: 42243177 Free article.
Large-scale computational predictions of human protein-protein interactions (PPIs) have recently enabled systematic mapping of the human interactome at near-atomic resolution. ...Together, these case studies underscore how large-scale computational predictions can b …
Large-scale computational predictions of human protein-protein interactions (PPIs) have recently enabled systematic mapping of the …
Kainic acid pig model of hippocampal epilepsy.
Mivalt F, Maltais D, Kim I, Kim J, Began P, Lopez AD, Krakorova V, Winter B, Kuo CY, Sharma S, Harty ES, Kim LH, Gregg N, Montonye DR, Gow CK, Miller KJ, Van Gompel J, Leyde K, Kremen V, Chang SY, Worrell GA. Mivalt F, et al. Sci Rep. 2026 Jun 4. doi: 10.1038/s41598-026-55135-2. Online ahead of print. Sci Rep. 2026. PMID: 42243171 Free article.
Translational large-animal models that can accommodate human-scale implantable devices are essential for advancing neuromodulation therapies in epilepsy. ...This porcine model reproduces electrophysiological features of human mTLE. This approach provides a powerful …
Translational large-animal models that can accommodate human-scale implantable devices are essential for advancing neuromodulation th …
Myosin light chain proteins cooperatively promote sarcomere growth in fast-twitch muscle.
Adekeye TE, Hupper TE, Easterbrooks TE, Teets EM, Tomak EA, Waterman SL, Sprague KA, White A, Coffin ML, Tanaka DK, Varga SM, Soares MT, Shepherd SJ, Austin JD, Krivorotko D, Perry ES, Amacher SL, Kelley JB, Talbot JC. Adekeye TE, et al. Nat Commun. 2026 Jun 4. doi: 10.1038/s41467-026-73861-z. Online ahead of print. Nat Commun. 2026. PMID: 42243126 Free article.
The mylpfa(-/-) defects can be rescued by Mylpfa-GFP, Mylpfb-GFP, and by human MYLPF-GFP with equivalent efficiency, but not by a MYLPF protein variant that causes Distal Arthrogryposis. ...
The mylpfa(-/-) defects can be rescued by Mylpfa-GFP, Mylpfb-GFP, and by human MYLPF-GFP with equivalent efficiency, but not by a MYL …
Structural dynamics of kappa opioid receptor interactions with β-arrestin 1.
Han J, Fine EJ, Jiang Q, Zhuang Y, Suomivuori CM, Chen ZW, Denn E, Whiddon K, Li K, Evers AS, Fuller J, Carter J, Fay JF, Chen M, Dror RO, Che T. Han J, et al. Nat Commun. 2026 Jun 4. doi: 10.1038/s41467-026-73968-3. Online ahead of print. Nat Commun. 2026. PMID: 42243110 Free article.
A computational model of reward learning and habits on social media.
Turner G, Gunschera LJ, Subrahmanya S, Salecha A, Eichstaedt JC, Palminteri S, Orben A. Turner G, et al. Nat Commun. 2026 Jun 4. doi: 10.1038/s41467-026-73547-6. Online ahead of print. Nat Commun. 2026. PMID: 42243108 Free article.
Social media have fundamentally transformed how we live and communicate. However, the methods to study how our cognitive systems interact with technology platforms are very limited. Computational modelling represents a new avenue to uncover the finegrained cognitive proces …
Social media have fundamentally transformed how we live and communicate. However, the methods to study how our cognitive systems inte …
Cognitive subtypes and brain network differences in antipsychotic-naïve first-episode psychosis.
Patton HN, Maximo JO, Luther L, Nelson EA, Lahti AC. Patton HN, et al. Schizophrenia (Heidelb). 2026 Jun 4. doi: 10.1038/s41537-026-00771-w. Online ahead of print. Schizophrenia (Heidelb). 2026. PMID: 42243092 Free article.
FEP participants and healthy controls (HC) completed the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), and premorbid intellectual functioning was estimated using The American National Adult Reading Test (AmNART). k-means clustering of RBANS do …
FEP participants and healthy controls (HC) completed the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), and pre …
A nucleus accumbens-projecting prefrontal cortex circuit underlies chronic social stress-induced depression-like behaviors.
Ma X, Kim H, Zhang L, Chen P, Wei J, Cui Y, Chen L, Xu Y, Zhang J, Dai Z, Ferguson D, Qiu S. Ma X, et al. Transl Psychiatry. 2026 Jun 4. doi: 10.1038/s41398-026-04128-w. Online ahead of print. Transl Psychiatry. 2026. PMID: 42243077 Free article.
Major depressive disorder (MDD) is a prevalent and debilitating psychiatric illness with limited treatment success. While chronic social stress is a well-established risk factor, the neural circuits that determine individual susceptibility or resilience to MDD remain poorl …
Major depressive disorder (MDD) is a prevalent and debilitating psychiatric illness with limited treatment success. While chronic social …
Psychoactive medication use and cardiac electrophysiology in hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorder: a retrospective analysis.
Kaushal R, Snyder I, Tale E, Jarkon L, Riley B, Cohen TJ. Kaushal R, et al. J Osteopath Med. 2026 Jun 5. doi: 10.1515/jom-2025-0053. Online ahead of print. J Osteopath Med. 2026. PMID: 42242906 Free article.
CONTEXT: Ehlers-Danlos syndrome (EDS) and hypermobility spectrum disorder (HSD) are connective tissue disorders associated with musculoskeletal manifestations and significant psychiatric comorbidities. ...Psychiatric diagnoses were classified per DSM-5 criteria, and psycho …
CONTEXT: Ehlers-Danlos syndrome (EDS) and hypermobility spectrum disorder (HSD) are connective tissue disorders associated with muscu …
The RNA-binding protein Imp1 promotes a Spdef transcriptional program and mucus fucosylation during necrotizing enterocolitis.
Swift KA, Shumway AJ, Aloia M, Hedges M, Pung R, Liu M, Rodriguez Santiago C, Shanahan MT, Drake A, Hakar MH, Selesner L, Kuhn M, Yung C, Sethupathy P, Andres SF. Swift KA, et al. Am J Physiol Gastrointest Liver Physiol. 2026 Jun 4. doi: 10.1152/ajpgi.00060.2026. Online ahead of print. Am J Physiol Gastrointest Liver Physiol. 2026. PMID: 42242905 Free article.
We aimed to define the role of IMP1 in NEC damage response using neonatal human enteroids and a NEC-like intestinal injury model. At post-natal day 3, wild-type mice or littermates with IEC-specific Imp1 overexpression (Imp1(IEC-OE)) or loss (Imp1( IEC)) were assigned to c …
We aimed to define the role of IMP1 in NEC damage response using neonatal human enteroids and a NEC-like intestinal injury model. At …
Ensuring continued access to essential inhaled respiratory medications: a call to action from the Inhaled Respiratory medicine Innovation and environmental Sustainability (IRIS) group.
Hurst JR, Kaplan A, van Boven JFM, Bhutani M, Han MK, Paulino E, Russell REK, Sawyer M, Trudzinski FC, van Ravenzwaay B, Winders T, Yorgancioglu A. Hurst JR, et al. Eur Respir J. 2026 Jun 4;67(6):2501873. doi: 10.1183/13993003.01873-2025. Print 2026 Jun. Eur Respir J. 2026. PMID: 42242746 Free PMC article.
It is, therefore, important to prescribe the "right" device to the appropriate patient. pMDIs deliver essential medications, as defined by the World Health Organization, and often are the only choice for some of the most vulnerable populations, including children <10 ye …
It is, therefore, important to prescribe the "right" device to the appropriate patient. pMDIs deliver essential medications, as defined by t …
CSIE: cancer subtyping via inference and ensemble.
Tran D, Thi-Hai Pham Y, Luu HN, Petereit J, Andrade-Rodriguez MA, Bya P, Nguyen T. Tran D, et al. Brief Bioinform. 2026 May 4;27(3):bbag290. doi: 10.1093/bib/bbag290. Brief Bioinform. 2026. PMID: 42242686 Free PMC article.
Expansion of pathogens and restoration of human skin microbiome in CD4 T-cell lymphopenia.
Han J, Lisco A, Che Y, Anderson MV, Laidlaw E, Kim CS, Hou P, Conlan S, Proctor DM, Lee-Lin S, Amirkhani A, Holmes CJ, Suh GS, Brownell I; NISC Comparative Sequencing Program; Segre JA, Sereti I, Kong HH. Han J, et al. J Invest Dermatol. 2026 Jun 3:S0022-202X(26)01274-1. doi: 10.1016/j.jid.2026.05.019. Online ahead of print. J Invest Dermatol. 2026. PMID: 42242497
Both patient groups carried pathogenic microbes, including high-oncogenic-risk human papillomaviruses (HPVs) and dermatophytes such as Trichophyton rubrum, which were rarely seen in healthy individuals. ...
Both patient groups carried pathogenic microbes, including high-oncogenic-risk human papillomaviruses (HPVs) and dermatophytes such a …
Pain and Opioid Use Among Black and White Patients with Cancer Using Remote Symptom Monitoring.
Dick JE, Olisakwe S, Williams CP, Azuero A, Henderson NL, Griffin RL, Eaton E, Rocque GB. Dick JE, et al. J Pain Symptom Manage. 2026 Jun 3:S0885-3924(26)00811-0. doi: 10.1016/j.jpainsymman.2026.05.016. Online ahead of print. J Pain Symptom Manage. 2026. PMID: 42242438
Opioid use before and during enrollment was extracted from the electronic health record. Multivariable mixed models evaluated associations between race, pain severity, and opioid use. ...
Opioid use before and during enrollment was extracted from the electronic health record. Multivariable mixed models evaluated associa …
IMPACT (Immune Monitoring and Phenotype Assessment of Clinical Trajectory) for Patients with Inborn Errors of Immunity from the Primary Immune Deficiency Treatment Consortium (PIDTC).
Arnold DE, Eissa H, Dunn E, Cuvelier GDE, Wright NAM, Marsh RA, Parikh S, Saldana BD, Vander Lugt MT, Bacchetta R, Satter LF, Chandrakasan S, Kellner E, Allenspach EJ, Schmitt EG, Logan B, Burroughs L, Cowan MJ, Griffith LM, Notarangelo L, Pai SY, Pulsipher MA, Dvorak CC, Haddad E, Puck JM, Torgerson TR, Leiding JW, Heimall J, Chan AY. Arnold DE, et al. J Allergy Clin Immunol Pract. 2026 Jun 3:S2213-2198(26)00443-5. doi: 10.1016/j.jaip.2026.05.025. Online ahead of print. J Allergy Clin Immunol Pract. 2026. PMID: 42242424
Experts from the Primary Immune Deficiency Treatment Consortium (PIDTC) identified essential features of severe combined immunodeficiency (SCID), chronic granulomatous disease (CGD), Wiskott-Aldrich syndrome (WAS), and primary immune regulatory disorders (PIRD) and compare …
Experts from the Primary Immune Deficiency Treatment Consortium (PIDTC) identified essential features of severe combined immunodeficiency (S …
Prioritizing chemicals for developmental neurotoxicity by integrating data from a new approach methods (NAMs) battery covering key cellular events in neurodevelopment.
Hall LA, Hsieh JH, Marvel SW, Behl M, Fritsche E, Koch K, Kreutz A, Leist M, Muriana A, Shafer TJ, Stanko JP, Sills RC, Hogberg HT, McPherson CA. Hall LA, et al. Neurotoxicology. 2026 Jun 3:103485. doi: 10.1016/j.neuro.2026.103485. Online ahead of print. Neurotoxicology. 2026. PMID: 42242322
Thousands of chemicals have not been assessed for developmental neurotoxicity (DNT) despite potential human exposure, prompting efforts to screen chemicals for possible DNT hazard using in vitro approaches. Ninety-five chemicals were screened in in a battery including in v …
Thousands of chemicals have not been assessed for developmental neurotoxicity (DNT) despite potential human exposure, prompting effor …
A novel US-based grading system for disease severity in sickle cell disease: the Sickle Cell Outcome Grading System (SCOGS).
Aurora T, Hodges R, Wardell JR, Barton M, Lipford J, Takemoto CM, Betensky M, Desai P, Jacob SA, Rai P, Strouse J, Hsu LL, Azul M, Hulbert M, Wang W, Talati R, Liem R, Alan S, Klings E, Appiah-Kubi A, Minniti C, Sisler I, McGann P, Vissa M, Nelson M, Guarino S, Miller R, Azar S, Badawy S, Abrams C, Lanzkron S, Saah E, Alvarez Nunez F, El-Amin N, Bhakta N, Hankins JS. Aurora T, et al. Lancet Haematol. 2026 Jun;13(6):e418-e425. doi: 10.1016/S2352-3026(26)00076-1. Lancet Haematol. 2026. PMID: 42242263 Review.
This workshop was funded by the project's NIH grant (1R01CA270157-01). The final classification includes 53 clinical outcomes, each with diagnostic criteria, grades, and temporal patterns. ...
This workshop was funded by the project's NIH grant (1R01CA270157-01). The final classification includes 53 clinical outcomes, each w …
Plasma signals of lung tumor promotion for molecular cancer prevention.
Pandya T, Zagorulya M, Leung MM, Augustine M, Liu LY, Leppä AM, Baruchel U, Ng SW, Klockner T, Mugabo M, Griffen AJ, Blyuss O, Iliakis CS, Grenov A, Haase K, Muller DC, Chan KH, Wu J, Burk VA, Wright N, Le Marois A, Pazukhina E, Ward S, Slawinski H, Pelletier M, Murphy C, Park MD, Snoeks T, Suarez-Bonnet A, Priestnall SL, Hardas A, Grieco C, Archer A, Celik A, Jimenez-Sanchez A, Scott R, Zahed H, Montégut L, Meza R, Durney CH, Lam S, Karasaki T, Vermeulen RCH, Xu H, Serrano-Fernandez P, Crnogorac-Jurcevic T, Menon U, Apostolidou S, Zaikin A, Gunu R, Whitwell HJ, Huang Z, Li Z, Hu X, Zhu B, Li L, Chirlaque MD, Guevara M, Kolijn PM, Guenoun A, Mookherjee N, Johansson M, Wang Z, Chatterjee N, Chiu CH, Chen Z, Pe'er D, Sahai E, Freytag S, Wack A, Gunter MJ, Merad M, Zhang J, Carlsten C, Yang PC, Chen HY, Platz EA, LaFave LM, Smith-Byrne K, Jamal-Hanjani M, Litchfield K, Nene NR, McGranahan N, Grönroos E, Hill W, Weeden CE, Swanton C. Pandya T, et al. Cell. 2026 Jun 4:S0092-8674(26)00522-2. doi: 10.1016/j.cell.2026.05.005. Online ahead of print. Cell. 2026. PMID: 42242224
An observational study of motivation and outcomes for training in Ayurveda.
Edwards MT, Gaylord SA. Edwards MT, et al. Explore (NY). 2026 May 30;22(5):103459. doi: 10.1016/j.explore.2026.103459. Online ahead of print. Explore (NY). 2026. PMID: 42241869
Perceived stress explains 5% of the variance in current self-rated health. Respondents chose to study Ayurveda to have meaningful work in helping others in combination with an interest in complementary/integrative medicine and an orientation towards health and spiri …
Perceived stress explains 5% of the variance in current self-rated health. Respondents chose to study Ayurveda to have meaningful wor …
Severe Maternal Morbidity and Breastfeeding Among Nulliparous Individuals in the United States.
Bank TC, Wu J, Catov J, Yee LM, Haas D, McNeil R, Ranzini AC, Simhan HN, Reddy U, Hoffman M, Silver RM, Levine L, Saade G, Chung J, Lynch CD, Grobman WA, Venkatesh KK. Bank TC, et al. Obstet Gynecol. 2026 Jun 4. doi: 10.1097/AOG.0000000000006345. Online ahead of print. Obstet Gynecol. 2026. PMID: 42241707
We examined whether severe maternal morbidity (SMM) at delivery was associated with the initiation and duration of breastfeeding among nulliparous individuals in the United States in a secondary analysis from the prospective nuMoM2b-HHS (Nulliparous Pregnancy Outcomes Study: Moni …
We examined whether severe maternal morbidity (SMM) at delivery was associated with the initiation and duration of breastfeeding among nulli …
Blunted experience of pleasure, unsystematic subjective value representation, and disrupted goal-directed behaviors: an ecological momentary assessment study across mood and psychotic disorders.
Dong X, Cooper JA, Moran EK, Barch DM. Dong X, et al. Schizophr Bull. 2026 Apr 10;52(3):sbag035. doi: 10.1093/schbul/sbag035. Schizophr Bull. 2026. PMID: 42241482 Free PMC article.
BACKGROUND: Motivational deficits are a core clinical feature across mood and psychotic disorders, although distinct mechanisms may contribute to similar symptom presentations. ...Moreover, systematic subjective value representation during effort-cost decision-making was a …
BACKGROUND: Motivational deficits are a core clinical feature across mood and psychotic disorders, although distinct mechanisms may c …
Largely Typical Neural Activation During Monetary Reward Receipt in People With Psychosis-Spectrum Disorders and First-Degree Relatives.
Purcell JR, Demro C, Lahud E, Burton PC, Simon JJ, Mueller BA, Sponheim SR. Purcell JR, et al. Schizophr Bull. 2026 Apr 10;52(3):sbag028. doi: 10.1093/schbul/sbag028. Schizophr Bull. 2026. PMID: 42241478
Furthermore, it is uncertain whether abnormal reward receipt neural functions are seen across psychosis-spectrum disorders or in people with genetic liability for psychosis. STUDY DESIGN: We compared behavior and brain activation during reward receipt in 123 people with ps …
Furthermore, it is uncertain whether abnormal reward receipt neural functions are seen across psychosis-spectrum disorders or in peop …
Comparative impacts and cost-effectiveness of tuberculosis systematic screening strategies in prisons in Brazil, Colombia, and Peru: A mathematical modeling study.
Liu YE, Bampi JVB, Arthur RF, Salindri AD, Busatto C, Jiménez PA, Pelissari DM, Johansen FDC, Arana-Narvaez R, Roca AFM, Solís Tupes WS, Jiu EM, Roca CAM, Abregú Contreras EA, Guizado VAA, Trujillo JT, Marcelino B, Gonzalez MA, Córdova Ayllon MC, Cohen T, Huaman MA, Goldhaber-Fiebert JD, Croda J, Andrews JR. Liu YE, et al. PLoS Med. 2026 Jun 4;23(6):e1004739. doi: 10.1371/journal.pmed.1004739. Online ahead of print. PLoS Med. 2026. PMID: 42241460 Free article.
Biannual screening alone remained cost-effective at prison incidence levels well below national averages, as well as at far lower willingness-to-pay thresholds. In settings without CXR-CAD, pooled Xpert was an impactful, cost-effective alternative. ...CONCLUSIONS: These mo …
Biannual screening alone remained cost-effective at prison incidence levels well below national averages, as well as at far lower wil …
Understanding one First Nations community's ways of healing from historical trauma.
Spillane NS, Weiss NH, Nalven T, Trinh CD, Egan A, Goldstein SC, Raudales AM, Kiefer R, Girard R, Gone JP, Moore RS. Spillane NS, et al. Psychol Trauma. 2026 Jun 4:10.1037/tra0002206. doi: 10.1037/tra0002206. Online ahead of print. Psychol Trauma. 2026. PMID: 42241099 Free PMC article.
Colonization functions as cultural trauma that dismantles Indigenous cultural resources, thereby creating and sustaining health disparities, so effective intervention must treat historical/cultural trauma. First Nations communities were healthy and thriving before colonial …
Colonization functions as cultural trauma that dismantles Indigenous cultural resources, thereby creating and sustaining health dispa …
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