Toft+DO - Search Results

1

Phase I study of tanespimycin in combination with bortezomib in patients with advanced solid malignancies.

Schenk E, Hendrickson AE, Northfelt D, Toft DO, Ames MM, Menefee M, Satele D, Qin R, Erlichman C. Schenk E, et al. Invest New Drugs. 2013 Oct;31(5):1251-6. doi: 10.1007/s10637-013-9946-7. Epub 2013 Mar 31. Invest New Drugs. 2013. PMID: 23543109 Free PMC article. Clinical Trial.

2

Characterization of plant p23-like proteins for their co-chaperone activities.

Zhang Z, Sullivan W, Felts SJ, Prasad BD, Toft DO, Krishna P. Zhang Z, et al. Cell Stress Chaperones. 2010 Sep;15(5):703-15. doi: 10.1007/s12192-010-0182-1. Epub 2010 Mar 28. Cell Stress Chaperones. 2010. PMID: 20349287 Free PMC article.

3

Phase I study of 17-allylamino-17 demethoxygeldanamycin, gemcitabine and/or cisplatin in patients with refractory solid tumors.

Hubbard J, Erlichman C, Toft DO, Qin R, Stensgard BA, Felten S, Ten Eyck C, Batzel G, Ivy SP, Haluska P. Hubbard J, et al. Invest New Drugs. 2011 Jun;29(3):473-80. doi: 10.1007/s10637-009-9381-y. Epub 2010 Jan 15. Invest New Drugs. 2011. PMID: 20082116 Free PMC article. Clinical Trial.

4

FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells.

Ni L, Yang CS, Gioeli D, Frierson H, Toft DO, Paschal BM. Ni L, et al. Mol Cell Biol. 2010 Mar;30(5):1243-53. doi: 10.1128/MCB.01891-08. Epub 2010 Jan 4. Mol Cell Biol. 2010. PMID: 20048054 Free PMC article.

5

Cisplatin abrogates the geldanamycin-induced heat shock response.

McCollum AK, Lukasiewicz KB, Teneyck CJ, Lingle WL, Toft DO, Erlichman C. McCollum AK, et al. Mol Cancer Ther. 2008 Oct;7(10):3256-64. doi: 10.1158/1535-7163.MCT-08-0157. Mol Cancer Ther. 2008. PMID: 18852129 Free PMC article.

6

P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response.

McCollum AK, TenEyck CJ, Stensgard B, Morlan BW, Ballman KV, Jenkins RB, Toft DO, Erlichman C. McCollum AK, et al. Cancer Res. 2008 Sep 15;68(18):7419-27. doi: 10.1158/0008-5472.CAN-07-5175. Cancer Res. 2008. PMID: 18794130 Free PMC article.

7

Minireview: the intersection of steroid receptors with molecular chaperones: observations and questions.

Smith DF, Toft DO. Smith DF, et al. Mol Endocrinol. 2008 Oct;22(10):2229-40. doi: 10.1210/me.2008-0089. Epub 2008 May 1. Mol Endocrinol. 2008. PMID: 18451092 Free PMC article. Review.

8

Recent Advances in the Study of hsp90 Structure and Mechanism of Action.

Toft DO. Toft DO. Trends Endocrinol Metab. 1998 Aug;9(6):238-43. doi: 10.1016/s1043-2760(98)00060-5. Trends Endocrinol Metab. 1998. PMID: 18406275

9

GCUNC45 is the first Hsp90 co-chaperone to show alpha/beta isoform specificity.

Chadli A, Felts SJ, Toft DO. Chadli A, et al. J Biol Chem. 2008 Apr 11;283(15):9509-12. doi: 10.1074/jbc.C800017200. Epub 2008 Feb 19. J Biol Chem. 2008. PMID: 18285346 Free PMC article.

10

Functioning of the Hsp90 machine in chaperoning checkpoint kinase I (Chk1) and the progesterone receptor (PR).

Felts SJ, Karnitz LM, Toft DO. Felts SJ, et al. Cell Stress Chaperones. 2007 Winter;12(4):353-63. doi: 10.1379/csc-299.1. Cell Stress Chaperones. 2007. PMID: 18229454 Free PMC article.

11

Up-regulation of heat shock protein 27 induces resistance to 17-allylamino-demethoxygeldanamycin through a glutathione-mediated mechanism.

McCollum AK, Teneyck CJ, Sauer BM, Toft DO, Erlichman C. McCollum AK, et al. Cancer Res. 2006 Nov 15;66(22):10967-75. doi: 10.1158/0008-5472.CAN-06-1629. Cancer Res. 2006. PMID: 17108135

12

A phase I trial of twice-weekly 17-allylamino-demethoxy-geldanamycin in patients with advanced cancer.

Nowakowski GS, McCollum AK, Ames MM, Mandrekar SJ, Reid JM, Adjei AA, Toft DO, Safgren SL, Erlichman C. Nowakowski GS, et al. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6087-93. doi: 10.1158/1078-0432.CCR-06-1015. Clin Cancer Res. 2006. PMID: 17062684 Clinical Trial.

13

Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones.

Arlander SJ, Felts SJ, Wagner JM, Stensgard B, Toft DO, Karnitz LM. Arlander SJ, et al. J Biol Chem. 2006 Feb 3;281(5):2989-98. doi: 10.1074/jbc.M508687200. Epub 2005 Dec 5. J Biol Chem. 2006. PMID: 16330544 Free article.

14

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.

Kovacs JJ, Murphy PJ, Gaillard S, Zhao X, Wu JT, Nicchitta CV, Yoshida M, Toft DO, Pratt WB, Yao TP. Kovacs JJ, et al. Mol Cell. 2005 May 27;18(5):601-7. doi: 10.1016/j.molcel.2005.04.021. Mol Cell. 2005. PMID: 15916966 Free article.

15

Interaction of the Hsp90 cochaperone cyclophilin 40 with Hsc70.

Carrello A, Allan RK, Morgan SL, Owen BA, Mok D, Ward BK, Minchin RF, Toft DO, Ratajczak T. Carrello A, et al. Cell Stress Chaperones. 2004 Summer;9(2):167-81. doi: 10.1379/csc-26r.1. Cell Stress Chaperones. 2004. PMID: 15497503 Free PMC article.

16

A novel in situ assay for the identification and characterization of soluble nuclear mobility factors.

Elbi C, Walker DA, Lewis M, Romero G, Sullivan WP, Toft DO, Hager GL, DeFranco DB. Elbi C, et al. Sci STKE. 2004 Jun 22;2004(238):pl10. doi: 10.1126/stke.2382004pl10. Sci STKE. 2004. PMID: 15213337

17

Molecular chaperones function as steroid receptor nuclear mobility factors.

Elbi C, Walker DA, Romero G, Sullivan WP, Toft DO, Hager GL, DeFranco DB. Elbi C, et al. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2876-81. doi: 10.1073/pnas.0400116101. Epub 2004 Feb 20. Proc Natl Acad Sci U S A. 2004. PMID: 14978266 Free PMC article.

18

p23, a simple protein with complex activities.

Felts SJ, Toft DO. Felts SJ, et al. Cell Stress Chaperones. 2003 Summer;8(2):108-13. doi: 10.1379/1466-1268(2003)008<0108:paspwc>2.0.co;2. Cell Stress Chaperones. 2003. PMID: 14627195 Free PMC article. Review.

19

Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress.

Arlander SJ, Eapen AK, Vroman BT, McDonald RJ, Toft DO, Karnitz LM. Arlander SJ, et al. J Biol Chem. 2003 Dec 26;278(52):52572-7. doi: 10.1074/jbc.M309054200. Epub 2003 Oct 21. J Biol Chem. 2003. PMID: 14570880 Free article.

20

Novel activation step required for transcriptional competence of progesterone receptor on chromatin templates.

Thackray VG, Toft DO, Nordeen SK. Thackray VG, et al. Mol Endocrinol. 2003 Dec;17(12):2543-53. doi: 10.1210/me.2003-0200. Epub 2003 Oct 9. Mol Endocrinol. 2003. PMID: 14551264

21

The Hsp90 chaperone complex as a novel target for cancer therapy.

Goetz MP, Toft DO, Ames MM, Erlichman C. Goetz MP, et al. Ann Oncol. 2003 Aug;14(8):1169-76. doi: 10.1093/annonc/mdg316. Ann Oncol. 2003. PMID: 12881371 Free article. Review.

22

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery.

Pratt WB, Toft DO. Pratt WB, et al. Exp Biol Med (Maywood). 2003 Feb;228(2):111-33. doi: 10.1177/153537020322800201. Exp Biol Med (Maywood). 2003. PMID: 12563018 Free article. Review.

23

The influence of ATP and p23 on the conformation of hsp90.

Sullivan WP, Owen BA, Toft DO. Sullivan WP, et al. J Biol Chem. 2002 Nov 29;277(48):45942-8. doi: 10.1074/jbc.M207754200. Epub 2002 Sep 24. J Biol Chem. 2002. PMID: 12324468 Free article.

24

The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex.

Hernández MP, Sullivan WP, Toft DO. Hernández MP, et al. J Biol Chem. 2002 Oct 11;277(41):38294-304. doi: 10.1074/jbc.M206566200. Epub 2002 Aug 2. J Biol Chem. 2002. PMID: 12161444 Free article.

25

HSP70 and HSP90 expression in leucocytes after exercise in moderately trained humans.

Shastry S, Toft DO, Joyner MJ. Shastry S, et al. Acta Physiol Scand. 2002 Jun;175(2):139-46. doi: 10.1046/j.1365-201X.2002.00979.x. Acta Physiol Scand. 2002. PMID: 12028134 Clinical Trial.

26

Effect of geldanamycin on androgen receptor function and stability.

Vanaja DK, Mitchell SH, Toft DO, Young CY. Vanaja DK, et al. Cell Stress Chaperones. 2002 Jan;7(1):55-64. doi: 10.1379/1466-1268(2002)007<0055:eogoar>2.0.co;2. Cell Stress Chaperones. 2002. PMID: 11894840 Free PMC article.

27

HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor.

Hernández MP, Chadli A, Toft DO. Hernández MP, et al. J Biol Chem. 2002 Apr 5;277(14):11873-81. doi: 10.1074/jbc.M111445200. Epub 2002 Jan 23. J Biol Chem. 2002. PMID: 11809754 Free article.

28

Regulation of heat shock protein 90 ATPase activity by sequences in the carboxyl terminus.

Owen BA, Sullivan WP, Felts SJ, Toft DO. Owen BA, et al. J Biol Chem. 2002 Mar 1;277(9):7086-91. doi: 10.1074/jbc.M111450200. Epub 2001 Dec 19. J Biol Chem. 2002. PMID: 11751892 Free article.

29

Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex.

Guo Y, Guettouche T, Fenna M, Boellmann F, Pratt WB, Toft DO, Smith DF, Voellmy R. Guo Y, et al. J Biol Chem. 2001 Dec 7;276(49):45791-9. doi: 10.1074/jbc.M105931200. Epub 2001 Oct 2. J Biol Chem. 2001. PMID: 11583998 Free article.

30

hsp70 interacting protein Hip does not affect glucocorticoid receptor folding by the hsp90-based chaperone machinery except to oppose the effect of BAG-1.

Kanelakis KC, Murphy PJ, Galigniana MD, Morishima Y, Takayama S, Reed JC, Toft DO, Pratt WB. Kanelakis KC, et al. Biochemistry. 2000 Nov 21;39(46):14314-21. doi: 10.1021/bi001671c. Biochemistry. 2000. PMID: 11087380

31

Dimerization and N-terminal domain proximity underlie the function of the molecular chaperone heat shock protein 90.

Chadli A, Bouhouche I, Sullivan W, Stensgard B, McMahon N, Catelli MG, Toft DO. Chadli A, et al. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12524-9. doi: 10.1073/pnas.220430297. Proc Natl Acad Sci U S A. 2000. PMID: 11050175 Free PMC article.

32

Hsp90 chaperone activity requires the full-length protein and interaction among its multiple domains.

Johnson BD, Chadli A, Felts SJ, Bouhouche I, Catelli MG, Toft DO. Johnson BD, et al. J Biol Chem. 2000 Oct 20;275(42):32499-507. doi: 10.1074/jbc.M005195200. J Biol Chem. 2000. PMID: 10913439 Free article.

33

Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone.

Weaver AJ, Sullivan WP, Felts SJ, Owen BA, Toft DO. Weaver AJ, et al. J Biol Chem. 2000 Jul 28;275(30):23045-52. doi: 10.1074/jbc.M003410200. J Biol Chem. 2000. PMID: 10811660 Free article.

34

The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies.

Freeman BC, Felts SJ, Toft DO, Yamamoto KR. Freeman BC, et al. Genes Dev. 2000 Feb 15;14(4):422-34. Genes Dev. 2000. PMID: 10691735 Free PMC article.

35

The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties.

Felts SJ, Owen BA, Nguyen P, Trepel J, Donner DB, Toft DO. Felts SJ, et al. J Biol Chem. 2000 Feb 4;275(5):3305-12. doi: 10.1074/jbc.275.5.3305. J Biol Chem. 2000. PMID: 10652318 Free article.

36

Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperones.

Schulte TW, Akinaga S, Murakata T, Agatsuma T, Sugimoto S, Nakano H, Lee YS, Simen BB, Argon Y, Felts S, Toft DO, Neckers LM, Sharma SV. Schulte TW, et al. Mol Endocrinol. 1999 Sep;13(9):1435-48. doi: 10.1210/mend.13.9.0339. Mol Endocrinol. 1999. PMID: 10478836

37

The importance of ATP binding and hydrolysis by hsp90 in formation and function of protein heterocomplexes.

Grenert JP, Johnson BD, Toft DO. Grenert JP, et al. J Biol Chem. 1999 Jun 18;274(25):17525-33. doi: 10.1074/jbc.274.25.17525. J Biol Chem. 1999. PMID: 10364185 Free article.

38

Functional requirement of p23 and Hsp90 in telomerase complexes.

Holt SE, Aisner DL, Baur J, Tesmer VM, Dy M, Ouellette M, Trager JB, Morin GB, Toft DO, Shay JW, Wright WE, White MA. Holt SE, et al. Genes Dev. 1999 Apr 1;13(7):817-26. doi: 10.1101/gad.13.7.817. Genes Dev. 1999. PMID: 10197982 Free PMC article.

39

ATP sensitive tryptophans of hsp90.

Bartha BB, Ajtai K, Toft DO, Burghardt TP. Bartha BB, et al. Biophys Chem. 1998 Jun 9;72(3):313-21. doi: 10.1016/s0301-4622(98)00114-8. Biophys Chem. 1998. PMID: 9691273

40

Differential interactions of p23 and the TPR-containing proteins Hop, Cyp40, FKBP52 and FKBP51 with Hsp90 mutants.

Chen S, Sullivan WP, Toft DO, Smith DF. Chen S, et al. Cell Stress Chaperones. 1998 Jun;3(2):118-29. doi: 10.1379/1466-1268(1998)003<0118:diopat>2.3.co;2. Cell Stress Chaperones. 1998. PMID: 9672247 Free PMC article.

41

Hsp90-containing multiprotein complexes in the eukaryotic microbe Achlya.

Brunt SA, Perdew GH, Toft DO, Silver JC. Brunt SA, et al. Cell Stress Chaperones. 1998 Mar;3(1):44-56. doi: 10.1379/1466-1268(1998)003<0044:hcmcit>2.3.co;2. Cell Stress Chaperones. 1998. PMID: 9585181 Free PMC article.

42

Hop modulates Hsp70/Hsp90 interactions in protein folding.

Johnson BD, Schumacher RJ, Ross ED, Toft DO. Johnson BD, et al. J Biol Chem. 1998 Feb 6;273(6):3679-86. doi: 10.1074/jbc.273.6.3679. J Biol Chem. 1998. PMID: 9452498 Free article.

43

The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation.

Grenert JP, Sullivan WP, Fadden P, Haystead TA, Clark J, Mimnaugh E, Krutzsch H, Ochel HJ, Schulte TW, Sausville E, Neckers LM, Toft DO. Grenert JP, et al. J Biol Chem. 1997 Sep 19;272(38):23843-50. doi: 10.1074/jbc.272.38.23843. J Biol Chem. 1997. PMID: 9295332 Free article.

44

Steroid receptor interactions with heat shock protein and immunophilin chaperones.

Pratt WB, Toft DO. Pratt WB, et al. Endocr Rev. 1997 Jun;18(3):306-60. doi: 10.1210/edrv.18.3.0303. Endocr Rev. 1997. PMID: 9183567 Review.

45

Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids.

Hu J, Toft DO, Seeger C. Hu J, et al. EMBO J. 1997 Jan 2;16(1):59-68. doi: 10.1093/emboj/16.1.59. EMBO J. 1997. PMID: 9009268 Free PMC article.

46

Molecular chaperone machines: chaperone activities of the cyclophilin Cyp-40 and the steroid aporeceptor-associated protein p23.

Freeman BC, Toft DO, Morimoto RI. Freeman BC, et al. Science. 1996 Dec 6;274(5293):1718-20. doi: 10.1126/science.274.5293.1718. Science. 1996. PMID: 8939864

47

Cooperative action of Hsp70, Hsp90, and DnaJ proteins in protein renaturation.

Schumacher RJ, Hansen WJ, Freeman BC, Alnemri E, Litwack G, Toft DO. Schumacher RJ, et al. Biochemistry. 1996 Nov 26;35(47):14889-98. doi: 10.1021/bi961825h. Biochemistry. 1996. PMID: 8942653

48

Molecular chaperoning of steroid hormone receptors.

Pratt WB, Gehring U, Toft DO. Pratt WB, et al. EXS. 1996;77:79-95. doi: 10.1007/978-3-0348-9088-5_6. EXS. 1996. PMID: 8856970 Review.

49

Estrogen response in the hFOB 1.19 human fetal osteoblastic cell line stably transfected with the human estrogen receptor gene.

Harris SA, Tau KR, Enger RJ, Toft DO, Riggs BL, Spelsberg TC. Harris SA, et al. J Cell Biochem. 1995 Oct;59(2):193-201. doi: 10.1002/jcb.240590209. J Cell Biochem. 1995. PMID: 8904314

50

The 23-kDa acidic protein in reticulocyte lysate is the weakly bound component of the hsp foldosome that is required for assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90.

Hutchison KA, Stancato LF, Owens-Grillo JK, Johnson JL, Krishna P, Toft DO, Pratt WB. Hutchison KA, et al. J Biol Chem. 1995 Aug 11;270(32):18841-7. doi: 10.1074/jbc.270.32.18841. J Biol Chem. 1995. PMID: 7642537 Free article.

51

Interaction of the progesterone receptor with binding proteins for FK506 and cyclosporin A.

Milad M, Sullivan W, Diehl E, Altmann M, Nordeen S, Edwards DP, Toft DO. Milad M, et al. Mol Endocrinol. 1995 Jul;9(7):838-47. doi: 10.1210/mend.9.7.7476967. Mol Endocrinol. 1995. PMID: 7476967

52

Binding of p23 and hsp90 during assembly with the progesterone receptor.

Johnson JL, Toft DO. Johnson JL, et al. Mol Endocrinol. 1995 Jun;9(6):670-8. doi: 10.1210/mend.9.6.8592513. Mol Endocrinol. 1995. PMID: 8592513

53

Accelerated recovery of postischemic stunned myocardium after induced expression of myocardial heat-shock protein (HSP70).

Robinson BL, Morita T, Toft DO, Morris JJ. Robinson BL, et al. J Thorac Cardiovasc Surg. 1995 Apr;109(4):753-64. doi: 10.1016/S0022-5223(95)70358-6. J Thorac Cardiovasc Surg. 1995. PMID: 7715224 Free article.

54

A novel chaperone complex for steroid receptors involving heat shock proteins, immunophilins, and p23.

Johnson JL, Toft DO. Johnson JL, et al. J Biol Chem. 1994 Oct 7;269(40):24989-93. J Biol Chem. 1994. PMID: 7929183 Free article.

55

ATP-dependent chaperoning activity of reticulocyte lysate.

Schumacher RJ, Hurst R, Sullivan WP, McMahon NJ, Toft DO, Matts RL. Schumacher RJ, et al. J Biol Chem. 1994 Apr 1;269(13):9493-9. J Biol Chem. 1994. PMID: 8144534 Free article.

56

Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes.

Johnson JL, Beito TG, Krco CJ, Toft DO. Johnson JL, et al. Mol Cell Biol. 1994 Mar;14(3):1956-63. doi: 10.1128/mcb.14.3.1956-1963.1994. Mol Cell Biol. 1994. PMID: 8114727 Free PMC article.

57

Mutational analysis of hsp90 binding to the progesterone receptor.

Sullivan WP, Toft DO. Sullivan WP, et al. J Biol Chem. 1993 Sep 25;268(27):20373-9. J Biol Chem. 1993. PMID: 8376394 Free article.

58

P59 (FK506 binding protein 59) interaction with heat shock proteins is highly conserved and may involve proteins other than steroid receptors.

Tai PK, Chang H, Albers MW, Schreiber SL, Toft DO, Faber LE. Tai PK, et al. Biochemistry. 1993 Aug 31;32(34):8842-7. doi: 10.1021/bi00085a015. Biochemistry. 1993. PMID: 7689858

59

Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70.

Smith DF, Sullivan WP, Marion TN, Zaitsu K, Madden B, McCormick DJ, Toft DO. Smith DF, et al. Mol Cell Biol. 1993 Feb;13(2):869-76. doi: 10.1128/mcb.13.2.869-876.1993. Mol Cell Biol. 1993. PMID: 8423808 Free PMC article.

60

Steroid receptors and their associated proteins.

Smith DF, Toft DO. Smith DF, et al. Mol Endocrinol. 1993 Jan;7(1):4-11. doi: 10.1210/mend.7.1.8446107. Mol Endocrinol. 1993. PMID: 8446107 Review. No abstract available.

61

Response of human breast cancer cells to heat shock and chemotherapeutic drugs.

Ciocca DR, Fuqua SA, Lock-Lim S, Toft DO, Welch WJ, McGuire WL. Ciocca DR, et al. Cancer Res. 1992 Jul 1;52(13):3648-54. Cancer Res. 1992. PMID: 1617638

62

Composition, assembly and activation of the avian progesterone receptor.

Smith DF, Toft DO. Smith DF, et al. J Steroid Biochem Mol Biol. 1992 Mar;41(3-8):201-7. doi: 10.1016/0960-0760(92)90345-j. J Steroid Biochem Mol Biol. 1992. PMID: 1562503

63

Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events.

Smith DF, Stensgard BA, Welch WJ, Toft DO. Smith DF, et al. J Biol Chem. 1992 Jan 15;267(2):1350-6. J Biol Chem. 1992. PMID: 1730655 Free article.

64

Characterization of progesterone receptor binding to the 90- and 70-kDa heat shock proteins.

Schowalter DB, Sullivan WP, Maihle NJ, Dobson AD, Conneely OM, O'Malley BW, Toft DO. Schowalter DB, et al. J Biol Chem. 1991 Nov 5;266(31):21165-73. J Biol Chem. 1991. PMID: 1939158 Free article.

65

Reconstitution of progesterone receptor with heat shock proteins.

Smith DF, Schowalter DB, Kost SL, Toft DO. Smith DF, et al. Mol Endocrinol. 1990 Nov;4(11):1704-11. doi: 10.1210/mend-4-11-1704. Mol Endocrinol. 1990. PMID: 2280772

66

Purification of unactivated progesterone receptor and identification of novel receptor-associated proteins.

Smith DF, Faber LE, Toft DO. Smith DF, et al. J Biol Chem. 1990 Mar 5;265(7):3996-4003. J Biol Chem. 1990. PMID: 2303491 Free article.

67

Progesterone-induced avidin as a marker of cytodifferentiation in the oviduct: comparison to ovalbumin.

Joensuu TK, Ylikomi TJ, Toft DO, Keinanen RA, Kulomaa MS, Tuohimaa PJ. Joensuu TK, et al. Endocrinology. 1990 Feb;126(2):1143-55. doi: 10.1210/endo-126-2-1143. Endocrinology. 1990. PMID: 2404743

68

A method of sequencing without subcloning and its application to the identification of a novel ORF with a sequence suggestive of a transcriptional regulator in the water mold Achlya ambisexualis.

Schowalter DB, Toft DO, Sommer SS. Schowalter DB, et al. Genomics. 1990 Jan;6(1):23-32. doi: 10.1016/0888-7543(90)90444-y. Genomics. 1990. PMID: 1689271

69

Loss of proliferative potential during terminal differentiation coincides with the decreased abundance of a subset of heterogeneous ribonuclear proteins.

Minoo P, Sullivan W, Solomon LR, Martin TE, Toft DO, Scott RE. Minoo P, et al. J Cell Biol. 1989 Nov;109(5):1937-46. doi: 10.1083/jcb.109.5.1937. J Cell Biol. 1989. PMID: 2808514 Free PMC article.

70

Immunofluorescence colocalization of the 90-kDa heat-shock protein and microtubules in interphase and mitotic mammalian cells.

Redmond T, Sanchez ER, Bresnick EH, Schlesinger MJ, Toft DO, Pratt WB, Welsh MJ. Redmond T, et al. Eur J Cell Biol. 1989 Oct;50(1):66-75. Eur J Cell Biol. 1989. PMID: 2693091

71

Binding of heat shock proteins to the avian progesterone receptor.

Kost SL, Smith DF, Sullivan WP, Welch WJ, Toft DO. Kost SL, et al. Mol Cell Biol. 1989 Sep;9(9):3829-38. doi: 10.1128/mcb.9.9.3829-3838.1989. Mol Cell Biol. 1989. PMID: 2779568 Free PMC article.

72

Immunocytochemical study of progesterone receptors in the human endometrium during the menstrual cycle.

Bergeron C, Ferenczy A, Toft DO, Schneider W, Shyamala G. Bergeron C, et al. Lab Invest. 1988 Dec;59(6):862-9. Lab Invest. 1988. PMID: 3199799

73

Immunocytochemical localization of estrogen-induced progestin receptors in guinea pig brain.

Blaustein JD, King JC, Toft DO, Turcotte J. Blaustein JD, et al. Brain Res. 1988 Nov 22;474(1):1-15. doi: 10.1016/0006-8993(88)90664-6. Brain Res. 1988. PMID: 3214702

74

Immunocytochemical study of progesterone receptors in hyperplastic and neoplastic endometrial tissues.

Bergeron C, Ferenczy A, Toft DO, Shyamala G. Bergeron C, et al. Cancer Res. 1988 Nov 1;48(21):6132-6. Cancer Res. 1988. PMID: 3167859

75

Hormone-dependent phosphorylation of the avian progesterone receptor.

Sullivan WP, Madden BJ, McCormick DJ, Toft DO. Sullivan WP, et al. J Biol Chem. 1988 Oct 15;263(29):14717-23. J Biol Chem. 1988. PMID: 3170562 Free article.

76

The production of antibodies against the conserved cysteine region of steroid receptors and their use in characterizing the avian progesterone receptor.

Smith DF, Lubahn DB, McCormick DJ, Wilson EM, Toft DO. Smith DF, et al. Endocrinology. 1988 Jun;122(6):2816-25. doi: 10.1210/endo-122-6-2816. Endocrinology. 1988. PMID: 2453349

77

Interaction of murine progesterone receptors with specific monoclonal antibodies to the avian progesterone receptor.

Schneider W, Toft DO, Sullivan WP, Shyamala G. Schneider W, et al. J Steroid Biochem. 1988 Mar;29(3):297-306. doi: 10.1016/0022-4731(88)90030-1. J Steroid Biochem. 1988. PMID: 3282125

78

Hormone-dependent processing of the avian progesterone receptor.

Sullivan WP, Smith DF, Beito TG, Krco CJ, Toft DO. Sullivan WP, et al. J Cell Biochem. 1988 Feb;36(2):103-19. doi: 10.1002/jcb.240360202. J Cell Biochem. 1988. PMID: 3356750

79

Studies with antibodies against the conserved cysteine region of progesterone receptor.

Smith DF, McCormick DJ, Toft DO. Smith DF, et al. J Steroid Biochem. 1988;30(1-6):1-7. doi: 10.1016/0022-4731(88)90069-6. J Steroid Biochem. 1988. PMID: 3386239

80

The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA.

Conneely OM, Maxwell BL, Toft DO, Schrader WT, O'Malley BW. Conneely OM, et al. Biochem Biophys Res Commun. 1987 Dec 16;149(2):493-501. doi: 10.1016/0006-291x(87)90395-0. Biochem Biophys Res Commun. 1987. PMID: 3426587

81

Structure-function properties of the chicken progesterone receptor A synthesized from complementary deoxyribonucleic acid.

Carson MA, Tsai MJ, Conneely OM, Maxwell BL, Clark JH, Dobson AD, Elbrecht A, Toft DO, Schrader WT, O'Malley BW. Carson MA, et al. Mol Endocrinol. 1987 Nov;1(11):791-801. doi: 10.1210/mend-1-11-791. Mol Endocrinol. 1987. PMID: 3153463

82

Immunologic analysis of human breast cancer progesterone receptors. 2. Structure, phosphorylation, and processing.

Wei LL, Sheridan PL, Krett NL, Francis MD, Toft DO, Edwards DP, Horwitz KB. Wei LL, et al. Biochemistry. 1987 Sep 22;26(19):6262-72. doi: 10.1021/bi00393a046. Biochemistry. 1987. PMID: 3689774

83

Immunologic analysis of human breast cancer progesterone receptors. 1. Immunoaffinity purification of transformed receptors and production of monoclonal antibodies.

Estes PA, Suba EJ, Lawler-Heavner J, Elashry-Stowers D, Wei LL, Toft DO, Sullivan WP, Horwitz KB, Edwards DP. Estes PA, et al. Biochemistry. 1987 Sep 22;26(19):6250-62. doi: 10.1021/bi00393a045. Biochemistry. 1987. PMID: 3689773

84

Sequence and expression of a functional chicken progesterone receptor.

Conneely OM, Dobson AD, Tsai MJ, Beattie WG, Toft DO, Huckaby CS, Zarucki T, Schrader WT, O'Malley BW. Conneely OM, et al. Mol Endocrinol. 1987 Aug;1(8):517-25. doi: 10.1210/mend-1-8-517. Mol Endocrinol. 1987. PMID: 3153474

85

Relationship of the 90-kDa murine heat shock protein to the untransformed and transformed states of the L cell glucocorticoid receptor.

Sanchez ER, Meshinchi S, Tienrungroj W, Schlesinger MJ, Toft DO, Pratt WB. Sanchez ER, et al. J Biol Chem. 1987 May 25;262(15):6986-91. J Biol Chem. 1987. PMID: 3294824 Free article.

86

Identification of the 90 kDa substrate of rat liver type II casein kinase with the heat shock protein which binds steroid receptors.

Dougherty JJ, Rabideau DA, Iannotti AM, Sullivan WP, Toft DO. Dougherty JJ, et al. Biochim Biophys Acta. 1987 Jan 19;927(1):74-80. doi: 10.1016/0167-4889(87)90067-x. Biochim Biophys Acta. 1987. PMID: 3466652

87

Nuclease resistance and the enrichment of native nuclear acceptor sites for the avian oviduct progesterone receptor.

Hora J, Horton MJ, Toft DO, Spelsberg TC. Hora J, et al. Proc Natl Acad Sci U S A. 1986 Dec;83(23):8839-43. doi: 10.1073/pnas.83.23.8839. Proc Natl Acad Sci U S A. 1986. PMID: 3466161 Free PMC article.

88

Preparation of monoclonal antibodies to the avian progesterone receptor.

Sullivan WP, Beito TG, Proper J, Krco CJ, Toft DO. Sullivan WP, et al. Endocrinology. 1986 Oct;119(4):1549-57. doi: 10.1210/endo-119-4-1549. Endocrinology. 1986. PMID: 2428599

89

Molecular cloning of the chicken progesterone receptor.

Conneely OM, Sullivan WP, Toft DO, Birnbaumer M, Cook RG, Maxwell BL, Zarucki-Schulz T, Greene GL, Schrader WT, O'Malley BW. Conneely OM, et al. Science. 1986 Aug 15;233(4765):767-70. doi: 10.1126/science.2426779. Science. 1986. PMID: 2426779

90

Peptide mapping analysis of the avian progesterone receptor.

Puri RK, Toft DO. Puri RK, et al. J Biol Chem. 1986 Apr 25;261(12):5651-7. J Biol Chem. 1986. PMID: 3514620 Free article.

91

A 90,000-dalton binding protein common to both steroid receptors and the Rous sarcoma virus transforming protein, pp60v-src.

Schuh S, Yonemoto W, Brugge J, Bauer VJ, Riehl RM, Sullivan WP, Toft DO. Schuh S, et al. J Biol Chem. 1985 Nov 15;260(26):14292-6. J Biol Chem. 1985. PMID: 2414293 Free article.

92

Immunological evidence that the nonhormone binding component of avian steroid receptors exists in a wide range of tissues and species.

Riehl RM, Sullivan WP, Vroman BT, Bauer VJ, Pearson GR, Toft DO. Riehl RM, et al. Biochemistry. 1985 Nov 5;24(23):6586-91. doi: 10.1021/bi00344a042. Biochemistry. 1985. PMID: 4084541

93

Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein.

Sanchez ER, Toft DO, Schlesinger MJ, Pratt WB. Sanchez ER, et al. J Biol Chem. 1985 Oct 15;260(23):12398-401. J Biol Chem. 1985. PMID: 3900074 Free article.

94

Effect of culture medium composition on pheromone receptor levels in Achlya ambisexualis.

Riehl RM, Toft DO. Riehl RM, et al. J Steroid Biochem. 1985 Oct;23(4):483-9. doi: 10.1016/0022-4731(85)90196-7. J Steroid Biochem. 1985. PMID: 4068709

95

Isolation of steroid receptor binding protein from chicken oviduct and production of monoclonal antibodies.

Sullivan WP, Vroman BT, Bauer VJ, Puri RK, Riehl RM, Pearson GR, Toft DO. Sullivan WP, et al. Biochemistry. 1985 Jul 16;24(15):4214-22. doi: 10.1021/bi00336a060. Biochemistry. 1985. PMID: 4052391

96

Analysis of the steroid receptor of Achlya ambisexualis.

Riehl RM, Toft DO. Riehl RM, et al. J Biol Chem. 1984 Dec 25;259(24):15324-30. doi: 10.1515/9783110885026.733. J Biol Chem. 1984. PMID: 6511795 Free article.

97

Transformation of highly purified avian progesterone receptor.

Puri RK, Toft DO. Puri RK, et al. Endocrinology. 1984 Dec;115(6):2453-63. doi: 10.1210/endo-115-6-2453. Endocrinology. 1984. PMID: 6499778

98

Detection of a pheromone-binding protein in the aquatic fungus Achlya ambisexualis.

Riehl RM, Toft DO, Meyer MD, Carlson GL, McMorris TC. Riehl RM, et al. Exp Cell Res. 1984 Aug;153(2):544-9. doi: 10.1016/0014-4827(84)90623-2. Exp Cell Res. 1984. PMID: 6734758

99

Characterization of an unusual sex steroid binding component from the chicken oviduct.

Ruh MF, Toft DO. Ruh MF, et al. J Steroid Biochem. 1984 Jul;21(1):1-8. doi: 10.1016/0022-4731(84)90052-9. J Steroid Biochem. 1984. PMID: 6540339

100

Polypeptide components of two 8 S forms of chicken oviduct progesterone receptor.

Dougherty JJ, Puri RK, Toft DO. Dougherty JJ, et al. J Biol Chem. 1984 Jun 25;259(12):8004-9. J Biol Chem. 1984. PMID: 6539778 Free article.

101

The avian progesterone receptor: isolation and characterization of phosphorylated forms.

Puri RK, Dougherty JJ, Toft DO. Puri RK, et al. J Steroid Biochem. 1984 Jan;20(1):23-9. doi: 10.1016/0022-4731(84)90184-5. J Steroid Biochem. 1984. PMID: 6708509

102

Comparison of estrogen receptors in human premenopausal and postmenopausal uteri using isoelectric focusing.

Pellikka PA, Sullivan WP, Coulam CB, Toft DO. Pellikka PA, et al. Obstet Gynecol. 1983 Oct;62(4):430-4. Obstet Gynecol. 1983. PMID: 6888820

103

Characterization and physiological variation of estrogen receptors in rabbit corpora lutea throughout pregnancy and pseudopregnancy: the effect of hysterectomy and sustained estradiol treatment.

Miller JB, Toft DO. Miller JB, et al. Biol Reprod. 1983 Oct;29(3):620-9. doi: 10.1095/biolreprod29.3.620. Biol Reprod. 1983. PMID: 6626646

104

Interaction of chick oviduct progesterone receptor with the 2',3'-dialdehyde derivative of adenosine 5'-triphosphate.

McBlain WA, Toft DO. McBlain WA, et al. Biochemistry. 1983 Apr 26;22(9):2262-70. doi: 10.1021/bi00278a032. Biochemistry. 1983. PMID: 6860663

105

Phosphorylation in vivo of chicken oviduct progesterone receptor.

Dougherty JJ, Puri RK, Toft DO. Dougherty JJ, et al. J Biol Chem. 1982 Dec 10;257(23):14226-30. J Biol Chem. 1982. PMID: 7142203 Free article.

106

Purification of "nontransformed" avian progesterone receptor and preliminary characterization.

Puri RK, Grandics P, Dougherty JJ, Toft DO. Puri RK, et al. J Biol Chem. 1982 Sep 25;257(18):10831-7. J Biol Chem. 1982. PMID: 7107635 Free article.

107

Radiochemical probes for steroid hormone receptors.

Toft DO, Wahner HW. Toft DO, et al. J Nucl Med. 1982 May;23(5):451-3. J Nucl Med. 1982. PMID: 7077399 Free article. No abstract available.

108

Characterization of two 8 S forms of chick oviduct progesterone receptor.

Dougherty JJ, Toft DO. Dougherty JJ, et al. J Biol Chem. 1982 Mar 25;257(6):3113-9. J Biol Chem. 1982. PMID: 7061469 Free article.

109

A new affinity resin for purification of non-transformed avian progesterone receptor.

Grandics P, Puri RK, Toft DO. Grandics P, et al. Endocrinology. 1982 Mar;110(3):1055-7. doi: 10.1210/endo-110-3-1055. Endocrinology. 1982. PMID: 7056221

110

Transformation of mammary cytoplasmic glucocorticoid receptor under cell-free conditions.

McBlain WA, Toft DO, Shyamala G. McBlain WA, et al. Biochemistry. 1981 Nov 24;20(24):6790-8. doi: 10.1021/bi00527a008. Biochemistry. 1981. PMID: 7317353

111

Concentration of cytosolic estrogen receptors in patients with postmenopausal osteoporosis.

Davidson BJ, Riggs BL, Coulam CB, Toft DO. Davidson BJ, et al. Am J Obstet Gynecol. 1980 Feb 15;136(4):430-3. doi: 10.1016/0002-9378(80)90666-3. Am J Obstet Gynecol. 1980. PMID: 7355923

112

An immunological comparison between mouse alpha-fetoprotein and the uterine estrogen receptor.

Toft DO, Tomasi TB Jr. Toft DO, et al. Proc Soc Exp Biol Med. 1978 Apr;157(4):594-8. doi: 10.3181/00379727-157-40104. Proc Soc Exp Biol Med. 1978. PMID: 77532 No abstract available.

113

Requirement for activation in the binding of progesterone receptor to ATP-Sepharose.

Miller JB, Toft DO. Miller JB, et al. Biochemistry. 1978 Jan 10;17(1):173-7. doi: 10.1021/bi00594a025. Biochemistry. 1978. PMID: 618540 No abstract available.

114

An improved method for the measurement of 1,25-(OH)2D3 in human plasma.

Lambert PW, Toft DO, Hodgson SF, Lindmark EA, Witrak BJ, Roos BA. Lambert PW, et al. Endocr Res Commun. 1978;5(4):293-310. doi: 10.1080/07435807809061094. Endocr Res Commun. 1978. PMID: 752633

115

Interaction of progesterone receptor with immobilized adenosine triphosphate.

Moudgil VK, Toft DO. Moudgil VK, et al. Biochim Biophys Acta. 1977 Feb 22;490(2):477-88. doi: 10.1016/0005-2795(77)90024-1. Biochim Biophys Acta. 1977. PMID: 836885

116

ATP-PPi exchange activity of progesterone receptor.

Moudgil VK, Toft DO. Moudgil VK, et al. Proc Natl Acad Sci U S A. 1976 Oct;73(10):3443-7. doi: 10.1073/pnas.73.10.3443. Proc Natl Acad Sci U S A. 1976. PMID: 185612 Free PMC article.

117

Inhibition of the binding of progesterone receptor to nuclei: effects of o-phenanthroline and rifamycin AF/013.

Lohmar PH, Toft DO. Lohmar PH, et al. Biochem Biophys Res Commun. 1975 Nov 3;67(1):8-15. doi: 10.1016/0006-291x(75)90275-2. Biochem Biophys Res Commun. 1975. PMID: 173315 No abstract available.

118

Binding of ATP to the progesterone receptor.

Moudgil VK, Toft DO. Moudgil VK, et al. Proc Natl Acad Sci U S A. 1975 Mar;72(3):901-5. doi: 10.1073/pnas.72.3.901. Proc Natl Acad Sci U S A. 1975. PMID: 165493 Free PMC article.

119

Progesterone-binding components of chick oviduct. VIII. Receptor activation and hormone-dependent binding to purified nuclei.

Buller RE, Toft DO, Schrader WT, O'Malley BW. Buller RE, et al. J Biol Chem. 1975 Feb 10;250(3):801-8. J Biol Chem. 1975. PMID: 163239 Free article.

120

Receptor identification by density gradient centrifugation.

Toft DO, Sherman MR. Toft DO, et al. Methods Enzymol. 1975;36:156-66. doi: 10.1016/s0076-6879(75)36017-5. Methods Enzymol. 1975. PMID: 162976 No abstract available.

121

Estrogen receptors in the chick oviduct.

Harrison RW, Toft DO. Harrison RW, et al. Endocrinology. 1975 Jan;96(1):199-205. doi: 10.1210/endo-96-1-199. Endocrinology. 1975. PMID: 162878

122

Binding of steroids to progesterone receptor proteins in chick oviduct and human uterus.

Smith HE, Smith RG, Toft DO, Neergaard JR, Burrows EP, O'Malley BW. Smith HE, et al. J Biol Chem. 1974 Sep 25;249(18):5924-32. J Biol Chem. 1974. PMID: 4369808 Free article. No abstract available.

123

Binding of chemical carcinogens in the lung.

Toft DO, Spelsberg TC. Toft DO, et al. J Natl Cancer Inst. 1974 Apr;52(4):1351-4. doi: 10.1093/jnci/52.4.1351. J Natl Cancer Inst. 1974. PMID: 4857034 No abstract available.

124

A specific progesterone receptor in the hamster uterus: physiologic properties and regulation during the estrous cycle.

Leavitt WW, Toft DO, Strott CA, O'Malley BW. Leavitt WW, et al. Endocrinology. 1974 Apr;94(4):1041-53. doi: 10.1210/endo-94-4-1041. Endocrinology. 1974. PMID: 4362041 No abstract available.

125

Glucocorticoid receptors in mouse pituitary tumor cells. II. Nuclear binding.

Watanabe H, Orth DN, Toft DO. Watanabe H, et al. Biochemistry. 1974 Jan 15;13(2):332-7. doi: 10.1021/bi00699a017. Biochemistry. 1974. PMID: 4358943 No abstract available.

126

Testosterone binding in the chick oviduct.

Harrison RW, Toft DO. Harrison RW, et al. Biochem Biophys Res Commun. 1973 Dec 10;55(3):857-63. doi: 10.1016/0006-291x(73)91223-0. Biochem Biophys Res Commun. 1973. PMID: 4357435 No abstract available.

127

In vitro binding of retinol to rat-tissue components.

Bashor MM, Toft DO, Chytil F. Bashor MM, et al. Proc Natl Acad Sci U S A. 1973 Dec;70(12):3483-7. doi: 10.1073/pnas.70.12.3483. Proc Natl Acad Sci U S A. 1973. PMID: 4519641 Free PMC article.

128

Glucocorticoid receptors in pituitary tumor cells. I. Cytosol receptors.

Watanabe H, Orth DN, Toft DO. Watanabe H, et al. J Biol Chem. 1973 Nov 25;248(22):7625-30. J Biol Chem. 1973. PMID: 4356254 Free article. No abstract available.

129

Characterization of a cytoplasmic receptor for 5alpha-dihydrotestosterone in the caput epididymidis of intact rabbits.

Danzo BJ, Orgebin-Crist MC, Toft DO. Danzo BJ, et al. Endocrinology. 1973 Jan;92(1):310-7. doi: 10.1210/endo-92-1-310. Endocrinology. 1973. PMID: 4681933 No abstract available.

130

A distinction between 3-methylcholanthrene and estrogen binding in the uterus.

Toft DO, Spelsberg TC. Toft DO, et al. Cancer Res. 1972 Dec;32(12):2743-6. Cancer Res. 1972. PMID: 4644207 No abstract available.

131

Progesterone binding in the mouse and rat uterus.

Feil PD, Glasser SR, Toft DO, O'Malley BW. Feil PD, et al. Endocrinology. 1972 Sep;91(3):738-46. doi: 10.1210/endo-91-3-738. Endocrinology. 1972. PMID: 5041206 No abstract available.

132

Progesterone-binding protein of chick oviduct. VI. Interaction of purified progesterone-receptor components with nuclear constituents.

Schrader WT, Toft DO, O'Malley BW. Schrader WT, et al. J Biol Chem. 1972 Apr 25;247(8):2401-7. J Biol Chem. 1972. PMID: 5019955 Free article. No abstract available.

133

Progesterone-binding components of chick oviduct. II. Nuclear components.

O'Malley BW, Toft DO, Sherman MR. O'Malley BW, et al. J Biol Chem. 1971 Feb 25;246(4):1117-22. J Biol Chem. 1971. PMID: 5543677 Free article. No abstract available.

134

Progesterone "receptors" in the cytoplasm and nucleus of chick oviduct target tissue.

O'Malley BW, Sherman MR, Toft DO. O'Malley BW, et al. Proc Natl Acad Sci U S A. 1970 Oct;67(2):501-8. doi: 10.1073/pnas.67.2.501. Proc Natl Acad Sci U S A. 1970. PMID: 5289005 Free PMC article.

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