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Page 1
Inferring chromosome segregation error stage and crossover in trisomic disorders with application to Down syndrome.
Li Z, Yang W, Wu G, Chang TC, Cheng Z, Devidas M, Shago M, Carroll AJ, Heerema NA, Gastier-Foster JM, Wood BL, Sanclemente L, Raetz EA, Hunger SP, Loh ML, Feingold E, Rosser TC, Allen EG, Sherman SL, Rabin KR, Lupo PJ, Yang JJ. Li Z, et al. Nat Commun. 2025 Jul 9;16(1):6316. doi: 10.1038/s41467-025-61413-w. Nat Commun. 2025. PMID: 40628699 Free PMC article.
STAT1-mediated interferon signatures are associated with preclinical JAK inhibitor sensitivity in T-ALL.
Xu J, Sussman JH, Yang A, Yoshimura S, Hu J, Chen C, Vincent T, Bandyopadhyay S, Li EY, Lim T, Elghawy O, Barsouk A, Karanfilovski D, Wald SL, Chen GM, Wu D, Newman H, Li A, Sun Y, Chen CH, Bernt K, Wood BL, Winter SS, Dunsmore KP, Raetz E, Devidas M, Pounds S, Loh M, Hunger SP, Chiang MY, Diorio C, Di Giacomo D, Pölönen P, Mullighan CG, Yang JJ, Tan K, Teachey DT. Xu J, et al. Blood. 2025 Jun 5;145(23):2793-2798. doi: 10.1182/blood.2025028566. Blood. 2025. PMID: 40101143
Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome.
Chen C, Xu J, Sussman JH, Vincent T, Tumulty JS, Yoshimura S, Alikarami F, Yu W, Ding YY, Chen CH, Li EY, Yang A, Qin X, Bandyopadhyay S, Peng J, Pölönen P, Newman H, Wood BL, Hu J, Shraim R, Hughes AD, Diorio C, Uppuluri L, Shi G, Ryan T, Fuller T, Loh ML, Raetz EA, Hunger SP, Pounds SB, Mullighan CG, Frank D, Yang JJ, Bernt KM, Teachey DT, Tan K. Chen C, et al. Blood. 2025 Jun 5;145(23):2685-2700. doi: 10.1182/blood.2024027270. Blood. 2025. PMID: 40089994 Free PMC article.
Molecular characterization informs prognosis in patients with localized Ewing sarcoma: A report from the Children's Oncology Group.
Gillani R, Shulman DS, DelRocco NJ, Klega K, Han R, Krailo MD, Slack JC, Tanhaemami M, Ward A, Bainer V, Ricker C, Sparks J, Bailey KM, Reed DR, DuBois SG, Leavey P, Mascarenhas L, Grohar PJ, Church AJ, Crompton BD, Janeway KA. Gillani R, et al. medRxiv [Preprint]. 2025 Jan 20:2025.01.20.25320840. doi: 10.1101/2025.01.20.25320840. medRxiv. 2025. PMID: 39974064 Free PMC article. Preprint.
Reply to: Accurate Determinants of Outcome in ALL.
Chang TC, Chen W, Qu C, Cheng Z, Elsayed A, Pounds SB, Shago M, Rabin KR, Raetz EA, Devidas M, Cheng C, Angiolillo A, Baviskar P, Borowitz M, Burke MJ, Carroll A, Carroll WL, Chen IM, Harvey R, Heerema N, Iacobucci I, Wang JR, Jeha S, Larsen E, Mattano L, Maloney K, Pui CH, Ramirez NC, Salzer W, Willman C, Winick N, Wood B, Hunger SP, Wu G, Mullighan CG, Loh ML. Chang TC, et al. J Clin Oncol. 2025 Mar 10;43(8):1039-1041. doi: 10.1200/JCO-24-02335. Epub 2024 Dec 23. J Clin Oncol. 2025. PMID: 39715469 No abstract available.
Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children.
Gupta S, Rau RE, Kairalla JA, Rabin KR, Wang C, Angiolillo AL, Alexander S, Carroll AJ, Conway S, Gore L, Kirsch I, Kubaney HR, Li AM, McNeer JL, Militano O, Miller TP, Moyer Y, O'Brien MM, Okada M, Reshmi SC, Shago M, Wagner E, Winick N, Wood BL, Haworth-Wright T, Zaman F, Zugmaier G, Zupanec S, Devidas M, Hunger SP, Teachey DT, Raetz EA, Loh ML. Gupta S, et al. N Engl J Med. 2025 Feb 27;392(9):875-891. doi: 10.1056/NEJMoa2411680. Epub 2024 Dec 7. N Engl J Med. 2025. PMID: 39651791 Free PMC article. Clinical Trial.
Heterogeneity of IKZF1 genomic alterations and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia.
Mullighan C, Wangondu R, Ashcraft E, Chang TC, Roberts K, Brady S, Fan Y, Evans W, Relling M, Crews K, Yang J, Yang W, Pounds S, Wu G, Devidas M, Maloney K, Mattano L Jr, Schore R, Angiolillo A, Larsen E, Salzer W, Burke M, Loh M, Jeha S, Pui CH, Inaba H, Cheng C. Mullighan C, et al. Res Sq [Preprint]. 2024 Nov 11:rs.3.rs-5292018. doi: 10.21203/rs.3.rs-5292018/v1. Res Sq. 2024. Update in: Leukemia. 2025 Jul;39(7):1595-1606. doi: 10.1038/s41375-025-02633-3. PMID: 39606455 Free PMC article. Updated. Preprint.
A multiomic atlas identifies a treatment-resistant, bone marrow progenitor-like cell population in T cell acute lymphoblastic leukemia.
Xu J, Chen C, Sussman JH, Yoshimura S, Vincent T, Pölönen P, Hu J, Bandyopadhyay S, Elghawy O, Yu W, Tumulty J, Chen CH, Li EY, Diorio C, Shraim R, Newman H, Uppuluri L, Li A, Chen GM, Wu DW, Ding YY, Xu JA, Karanfilovski D, Lim T, Hsu M, Thadi A, Ahn KJ, Wu CY, Peng J, Sun Y, Wang A, Mehta R, Frank D, Meyer L, Loh ML, Raetz EA, Chen Z, Wood BL, Devidas M, Dunsmore KP, Winter SS, Chang TC, Wu G, Pounds SB, Zhang NR, Carroll W, Hunger SP, Bernt K, Yang JJ, Mullighan CG, Tan K, Teachey DT. Xu J, et al. Nat Cancer. 2025 Jan;6(1):102-122. doi: 10.1038/s43018-024-00863-5. Epub 2024 Nov 25. Nat Cancer. 2025. PMID: 39587259 Free PMC article.
Palbociclib in Solid Tumor Patients With Genomic Alterations in the cyclinD-cdk4/6-INK4a-Rb Pathway: Results From National Cancer Institute-Children's Oncology Group Pediatric Molecular Analysis for Therapy Choice Trial Arm I (APEC1621I).
Macy ME, Mody R, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Fox E, Weigel BJ, Hawkins DS, Mooney MM, Williams PM, Patton DR, Coffey BD, Roy-Chowdhuri S, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DW. Macy ME, et al. JCO Precis Oncol. 2024 Sep;8:e2400418. doi: 10.1200/PO-24-00418. JCO Precis Oncol. 2024. PMID: 39298716 Clinical Trial.
Phase II Study of Samotolisib in Children and Young Adults With Tumors Harboring Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Pathway Alterations: Pediatric MATCH APEC1621D.
Laetsch TW, Ludwig K, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey B, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Mhlanga J, Fox E, Weigel BJ, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DW. Laetsch TW, et al. JCO Precis Oncol. 2024 Sep;8:e2400258. doi: 10.1200/PO.24.00258. JCO Precis Oncol. 2024. PMID: 39298693 Clinical Trial.
Impact of Genetic Ancestry on T-cell Acute Lymphoblastic Leukemia Outcomes.
Teachey D, Newman H, Lee S, Pölönen P, Shraim R, Li Y, Liu H, Aplenc R, Bandyopadhyay S, Chen C, Chen Z, Devidas M, Diorio C, Dunsmore K, Elghawy O, Elhachimi A, Fuller T, Gupta S, Hall J, Hughes A, Hunger S, Loh M, Martinez Z, McCoy M, Mullen C, Pounds S, Raetz E, Ryan T, Seffernick A, Shi G, Sussman J, Tan K, Uppuluri L, Vincent TL, Wang'ondu R, Winestone L, Winter S, Wood B, Wu G, Xu J, Yang W, Mullighan C, Yang J, Bona K. Teachey D, et al. Res Sq [Preprint]. 2024 Aug 16:rs.3.rs-4858231. doi: 10.21203/rs.3.rs-4858231/v1. Res Sq. 2024. Update in: Blood Cancer Discov. 2025 May 28. doi: 10.1158/2643-3230.BCD-25-0049. PMID: 39184069 Free PMC article. Updated. Preprint.
The genomic basis of childhood T-lineage acute lymphoblastic leukaemia.
Pölönen P, Di Giacomo D, Seffernick AE, Elsayed A, Kimura S, Benini F, Montefiori LE, Wood BL, Xu J, Chen C, Cheng Z, Newman H, Myers J, Iacobucci I, Li E, Sussman J, Hedges D, Hui Y, Diorio C, Uppuluri L, Frank D, Fan Y, Chang Y, Meshinchi S, Ries R, Shraim R, Li A, Bernt KM, Devidas M, Winter SS, Dunsmore KP, Inaba H, Carroll WL, Ramirez NC, Phillips AH, Kriwacki RW, Yang JJ, Vincent TL, Zhao Y, Ghate PS, Wang J, Reilly C, Zhou X, Sanders MA, Takita J, Kato M, Takasugi N, Chang BH, Press RD, Loh M, Rampersaud E, Raetz E, Hunger SP, Tan K, Chang TC, Wu G, Pounds SB, Mullighan CG, Teachey DT. Pölönen P, et al. Nature. 2024 Aug;632(8027):1082-1091. doi: 10.1038/s41586-024-07807-0. Epub 2024 Aug 14. Nature. 2024. PMID: 39143224 Free PMC article.
Genomic Determinants of Outcome in Acute Lymphoblastic Leukemia.
Chang TC, Chen W, Qu C, Cheng Z, Hedges D, Elsayed A, Pounds SB, Shago M, Rabin KR, Raetz EA, Devidas M, Cheng C, Angiolillo A, Baviskar P, Borowitz M, Burke MJ, Carroll A, Carroll WL, Chen IM, Harvey R, Heerema N, Iacobucci I, Wang JR, Jeha S, Larsen E, Mattano L, Maloney K, Pui CH, Ramirez NC, Salzer W, Willman C, Winick N, Wood B, Hunger SP, Wu G, Mullighan CG, Loh ML. Chang TC, et al. J Clin Oncol. 2024 Oct 10;42(29):3491-3503. doi: 10.1200/JCO.23.02238. Epub 2024 Aug 9. J Clin Oncol. 2024. PMID: 39121442 Free PMC article.
Phase II Study of Ulixertinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Alterations: APEC1621J of the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial.
Vo KT, Sabnis AJ, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey B, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Jaju A, Fox E, Weigel BJ, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DW. Vo KT, et al. JCO Precis Oncol. 2024 Jun;8:e2400103. doi: 10.1200/PO.24.00103. JCO Precis Oncol. 2024. PMID: 38935895 Free PMC article. Clinical Trial.
Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk.
Kimura S, Park CS, Montefiori LE, Iacobucci I, Pölönen P, Gao Q, Arnold ED, Attarbaschi A, Brown A, Buldini B, Caldwell KJ, Chang Y, Chen C, Cheng C, Cheng Z, Choi J, Conter V, Crews KR, de Groot-Kruseman HA, Deguchi T, Eguchi M, Muhle HE, Elitzur S, Escherich G, Freeman BB 3rd, Gu Z, Han K, Horibe K, Imamura T, Jeha S, Kato M, Chiew KH, Khan T, Kicinski M, Köhrer S, Kornblau SM, Kotecha RS, Li CK, Liu YC, Locatelli F, Luger SM, Paietta EM, Manabe A, Marquart HV, Masetti R, Maybury M, Mazilier P, Meijerink JPP, Mitchell S, Miyamura T, Moore AS, Oshima K, Pawinska-Wasikowska K, Pieters R, Prater MS, Pruett-Miller SM, Pui CH, Qu C, Reiterova M, Reyes N, Roberts KG, Rowe JM, Sato A, Schmiegelow K, Schrappe M, Shen S, Skoczeń S, Spinelli O, Stary J, Svaton M, Takagi M, Takita J, Tang Y, Teachey DT, Thomas PG, Tomizawa D, Trka J, Varotto E, Vincent TL, Yang JJ, Yeoh AEJ, Zhou Y, Zimmermann M, Inaba H, Mullighan CG. Kimura S, et al. Cancer Discov. 2024 Oct 4;14(10):1838-1859. doi: 10.1158/2159-8290.CD-23-1452. Cancer Discov. 2024. PMID: 38916500 Free PMC article.
Artificial intelligence-based morphologic classification and molecular characterization of neuroblastic tumors from digital histopathology.
Applebaum M, Ramesh S, Dyer E, Pomaville M, Doytcheva K, Dolezal J, Kochanny S, Terhaar R, Mehrhoff C, Patel K, Brewer J, Kusswurm B, Naranjo A, Shimada H, Sokol E, Cohn S, George R, Pearson A. Applebaum M, et al. Res Sq [Preprint]. 2024 Jun 4:rs.3.rs-4396782. doi: 10.21203/rs.3.rs-4396782/v1. Res Sq. 2024. Update in: NPJ Precis Oncol. 2024 Nov 8;8(1):255. doi: 10.1038/s41698-024-00745-0. PMID: 38883758 Free PMC article. Updated. Preprint.
Phase II study of vemurafenib in children and young adults with tumors harboring BRAF V600 mutations: NCI-COG pediatric MATCH trial (APEC1621) Arm G.
Nelson MV, Kim A, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey BD, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Ramirez NC, Jaju A, Fox E, Weigel BJ, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DW. Nelson MV, et al. Oncologist. 2024 Aug 5;29(8):723-e1093. doi: 10.1093/oncolo/oyae119. Oncologist. 2024. PMID: 38873934 Free PMC article. Clinical Trial.
Olaparib for childhood tumors harboring defects in DNA damage repair genes: arm H of the NCI-COG Pediatric MATCH trial.
Glade Bender JL, Pinkney K, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey BD, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Ramirez NC, Fox E, Weigel BJ, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DW. Glade Bender JL, et al. Oncologist. 2024 Jul 5;29(7):638-e952. doi: 10.1093/oncolo/oyae096. Oncologist. 2024. PMID: 38815151 Free PMC article. Clinical Trial.
Rare germline structural variants increase risk for pediatric solid tumors.
Gillani R, Collins RL, Crowdis J, Garza A, Jones JK, Walker M, Sanchis-Juan A, Whelan C, Pierce-Hoffman E, Talkowski M, Brand H, Haigis K, LoPiccolo J, AlDubayan SH, Gusev A, Crompton BD, Janeway KA, Van Allen EM. Gillani R, et al. bioRxiv [Preprint]. 2024 Apr 29:2024.04.27.591484. doi: 10.1101/2024.04.27.591484. bioRxiv. 2024. Update in: Science. 2025 Jan 3;387(6729):eadq0071. doi: 10.1126/science.adq0071. PMID: 38746320 Free PMC article. Updated. Preprint.
Bilateral Wilms tumor with anaplasia: A report from the Children's Oncology Group Study AREN0534.
Romao RLP, Aldrink JH, Renfro LA, Mullen EA, Murphy AJ, Brzezinski J, Malek MM, Benedetti DJ, Cost NG, Smith E, Dome JS, Davidoff AM, Treece A, Parsons LN, Fernandez CV, Tornwall B, Shamberger RC, Paulino A, Kalapurakal JA, Geller JI, Ehrlich PF. Romao RLP, et al. Pediatr Blood Cancer. 2024 Jul;71(7):e30981. doi: 10.1002/pbc.30981. Epub 2024 Apr 18. Pediatr Blood Cancer. 2024. PMID: 38637871 Free PMC article.
Germline Genetic Testing and Survival Outcomes Among Children With Rhabdomyosarcoma: A Report From the Children's Oncology Group.
Martin-Giacalone BA, Li H, Scheurer ME, Casey DL, Dugan-Perez S, Marquez-Do DA, Muzny D, Gibbs RA, Barkauskas DA, Hall D, Stewart DR, Schiffman JD, McEvoy MT, Khan J, Malkin D, Linardic CM, Crompton BD, Shern JF, Skapek SX, Venkatramani R, Hawkins DS, Sabo A, Plon SE, Lupo PJ. Martin-Giacalone BA, et al. JAMA Netw Open. 2024 Mar 4;7(3):e244170. doi: 10.1001/jamanetworkopen.2024.4170. JAMA Netw Open. 2024. PMID: 38546643 Free PMC article.
MRD at the end of induction and EFS in T-cell lymphoblastic lymphoma: Children's Oncology Group trial AALL1231.
Hayashi RJ, Hermiston ML, Wood BL, Teachey DT, Devidas M, Chen Z, Annett RD, Asselin BL, August K, Cho S, Dunsmore KP, Freedman JL, Galardy PJ, Harker-Murray P, Horton TM, Jaju A, Lam A, Messinger YH, Miles RR, Okada M, Patel S, Schafer ES, Schechter T, Shimano KA, Singh N, Steele A, Sulis ML, Vargas SL, Winter SS, Wood C, Zweidler-McKay PA, Loh ML, Hunger SP, Raetz EA, Bollard CM, Allen CE. Hayashi RJ, et al. Blood. 2024 May 16;143(20):2053-2058. doi: 10.1182/blood.2023021184. Blood. 2024. PMID: 38457359 Free PMC article. Clinical Trial.
Enhanced Risk Stratification for Children and Young Adults with B-Cell Acute Lymphoblastic Leukemia: A Children's Oncology Group Report.
DelRocco NJ, Loh ML, Borowitz MJ, Gupta S, Rabin KR, Zweidler-McKay P, Maloney KW, Mattano LA, Larsen E, Angiolillo A, Schore RJ, Burke MJ, Salzer WL, Wood BL, Carroll AJ, Heerema NA, Reshmi SC, Gastier-Foster JM, Harvey R, Chen IM, Roberts KG, Mullighan CG, Willman C, Winick N, Carroll WL, Rau RE, Teachey DT, Hunger SP, Raetz EA, Devidas M, Kairalla JA. DelRocco NJ, et al. Leukemia. 2024 Apr;38(4):720-728. doi: 10.1038/s41375-024-02166-1. Epub 2024 Feb 15. Leukemia. 2024. PMID: 38360863 Free PMC article.
Race and Ethnic Group Enrollment and Outcomes for Wilms Tumor: Analysis of the Current Era Children's Oncology Group Study, AREN03B2.
Lovvorn HN 3rd, Renfro LA, Benedetti DJ, Kotagal M, Phelps HM, Ehrlich PF, Lo AC, Sandberg JK, Treece AL, Gow KW, Glick RD, Davidoff AM, Cost NG, Dix DB, Fernandez CV, Dome JS, Geller JI, Mullen EA. Lovvorn HN 3rd, et al. J Am Coll Surg. 2024 Apr 1;238(4):733-749. doi: 10.1097/XCS.0000000000000999. Epub 2024 Mar 15. J Am Coll Surg. 2024. PMID: 38251681 Free PMC article.
Osteosarcoma Explorer: A Data Commons With Clinical, Genomic, Protein, and Tissue Imaging Data for Osteosarcoma Research.
Yang DM, Zhou Q, Furman-Cline L, Cheng X, Luo D, Lai H, Li Y, Jin KW, Yao B, Leavey PJ, Rakheja D, Lo T, Hall D, Barkauskas DA, Shulman DS, Janeway K, Khanna C, Gorlick R, Menzies C, Zhan X, Xiao G, Skapek SX, Xu L, Klesse LJ, Crompton BD, Xie Y. Yang DM, et al. JCO Clin Cancer Inform. 2023 Sep;7:e2300104. doi: 10.1200/CCI.23.00104. JCO Clin Cancer Inform. 2023. PMID: 37956387 Free PMC article.
Treatment of children with favorable histology Wilms tumor with extrapulmonary metastases: A report from the COG studies AREN0533 and AREN03B2 and NWTSG study NWTS-5.
Benedetti DJ, Varela CR, Renfro LA, Tornwall B, Dix DB, Ehrlich PF, Glick RD, Kalapurakal J, Perlman E, Gratias E, Seibel NL, Geller JI, Khanna G, Malogolowkin M, Grundy P, Fernandez CV, Dome JS, Mullen EA. Benedetti DJ, et al. Cancer. 2024 Mar 15;130(6):947-961. doi: 10.1002/cncr.35099. Epub 2023 Nov 7. Cancer. 2024. PMID: 37933882 Free PMC article. Clinical Trial.
Outcomes in Children, Adolescents, and Young Adults With Down Syndrome and ALL: A Report From the Children's Oncology Group.
Rabin KR, Devidas M, Chen Z, Ji L, Kairalla J, Hitzler JK, Yang JJ, Carroll AJ, Heerema NA, Borowitz MJ, Wood BL, Roberts KG, Mullighan CG, Harvey RC, Chen IM, Willman CL, Reshmi SC, Gastier-Foster JM, Bhojwani D, Rheingold SR, Maloney KW, Mattano LA, Larsen EC, Schore RJ, Burke MJ, Salzer WL, Winick NJ, Carroll WL, Raetz EA, Loh ML, Hunger SP, Angiolillo AL. Rabin KR, et al. J Clin Oncol. 2024 Jan 10;42(2):218-227. doi: 10.1200/JCO.23.00389. Epub 2023 Oct 27. J Clin Oncol. 2024. PMID: 37890117 Free PMC article.
Children's Oncology Group's 2023 blueprint for research: Bone tumors.
Reed DR, Grohar P, Rubin E, Binitie O, Krailo M, Davis J, DuBois SG, Janeway KA. Reed DR, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30583. doi: 10.1002/pbc.30583. Epub 2023 Jul 27. Pediatr Blood Cancer. 2023. PMID: 37501549 Free PMC article.
Children's Oncology Group's 2023 blueprint for research: Liver tumors.
O'Neill AF, Meyers RL, Katzenstein HM, Geller JI, Tiao GM, López-Terrada D, Malogolowkin M; Liver Tumor Committee. O'Neill AF, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30576. doi: 10.1002/pbc.30576. Epub 2023 Jul 26. Pediatr Blood Cancer. 2023. PMID: 37495540 Free PMC article.
Children's Oncology Group's 2023 blueprint for research: Myeloid neoplasms.
Cooper TM, Alonzo TA, Tasian SK, Kutny MA, Hitzler J, Pollard JA, Aplenc R, Meshinchi S, Kolb EA. Cooper TM, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30584. doi: 10.1002/pbc.30584. Epub 2023 Jul 21. Pediatr Blood Cancer. 2023. PMID: 37480164 Free PMC article.
Children's Oncology Group's 2023 blueprint for research: Renal tumors.
Geller JI, Hong AL, Vallance KL, Evageliou N, Aldrink JH, Cost NG, Treece AL, Renfro LA, Mullen EA; COG Renal Tumor Committee. Geller JI, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30586. doi: 10.1002/pbc.30586. Epub 2023 Jul 21. Pediatr Blood Cancer. 2023. PMID: 37477907 Free PMC article.
Children's Oncology Group's 2023 blueprint for research: Rare tumors.
Schultz KAP, Chintagumpala M, Piao J, Chen KS, Gartrell R, Christison-Lagay E, Berry JL, Shah R, Laetsch TW; Children's Oncology Group Rare Tumor Committee. Schultz KAP, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30574. doi: 10.1002/pbc.30574. Epub 2023 Jul 17. Pediatr Blood Cancer. 2023. PMID: 37458616 Free PMC article.
Children's Oncology Group's 2023 blueprint for research: Germ cell tumors.
Bhuta R, Shah R, Gell JJ, Poynter JN, Bagrodia A, Dicken BJ, Pashankar F, Frazier AL, Shaikh F. Bhuta R, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30562. doi: 10.1002/pbc.30562. Epub 2023 Jul 14. Pediatr Blood Cancer. 2023. PMID: 37449938 Free PMC article.
Children's Oncology Group's 2023 blueprint for research: Non-Hodgkin lymphoma.
El-Mallawany NK, Alexander S, Fluchel M, Hayashi RJ, Lowe EJ, Giulino-Roth L, Wistinghausen B, Hermiston M, Allen CE; COG NHL Committee. El-Mallawany NK, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30565. doi: 10.1002/pbc.30565. Epub 2023 Jul 14. Pediatr Blood Cancer. 2023. PMID: 37449925 Free PMC article.
Children's Oncology Group's 2023 blueprint for research.
Hawkins DS, Gore L. Hawkins DS, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30569. doi: 10.1002/pbc.30569. Epub 2023 Jul 11. Pediatr Blood Cancer. 2023. PMID: 37433635 Free PMC article. No abstract available.
Children's Oncology Group's 2023 blueprint for research: Soft tissue sarcomas.
Oberoi S, Crane JN, Haduong JH, Rudzinski ER, Wolden SL, Dasgupta R, Linardic CM, Weiss AR, Venkatramani R; the Children's Oncology Group Soft Tissue Sarcoma Committee. Oberoi S, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30556. doi: 10.1002/pbc.30556. Epub 2023 Jul 10. Pediatr Blood Cancer. 2023. PMID: 37430436 Free PMC article.
Reply to Z.R. McCaw et al.
Farrar JE, Othus M, Wang YC, Alonzo TA, Meshinchi S. Farrar JE, et al. J Clin Oncol. 2023 Sep 20;41(27):4447. doi: 10.1200/JCO.23.00986. Epub 2023 Jun 30. J Clin Oncol. 2023. PMID: 37390387 Free PMC article. No abstract available.
Valosin-containing protein (VCP/p97) is prognostically unfavorable in pediatric AML, and negatively correlates with unfolded protein response proteins IRE1 and GRP78: A report from the Children's Oncology Group.
Hoff FW, Qiu Y, Brown BD, Gerbing RB, Leonti AR, Ries RE, Gamis AS, Aplenc R, Kolb EA, Alonzo TA, Meshinchi S, Jenkins GN, Horton TM, Kornblau SM. Hoff FW, et al. Proteomics Clin Appl. 2023 Nov;17(6):e2200109. doi: 10.1002/prca.202200109. Epub 2023 Jun 7. Proteomics Clin Appl. 2023. PMID: 37287368 Free PMC article.
Tazemetostat for tumors harboring SMARCB1/SMARCA4 or EZH2 alterations: results from NCI-COG pediatric MATCH APEC1621C.
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Outstanding outcomes with two low intensity regimens in children with low-risk B-ALL: a report from COG AALL0932.
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Actionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial.
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Phase II Trial of Inotuzumab Ozogamicin in Children and Adolescents With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia: Children's Oncology Group Protocol AALL1621.
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Assessment of Arsenic Trioxide and All-trans Retinoic Acid for the Treatment of Pediatric Acute Promyelocytic Leukemia: A Report From the Children's Oncology Group AAML1331 Trial.
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Reduced-intensity conditioning hematopoietic stem cell transplantation for chronic lymphocytic leukemia and Richter's transformation.
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Haplotype-resolved germline and somatic alterations in renal medullary carcinomas.
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Therapeutic potential of ruxolitinib and ponatinib in patients with EPOR-rearranged Philadelphia chromosome-like acute lymphoblastic leukemia.
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Children's Oncology Group Phase III Trial of Reduced-Dose and Reduced-Volume Radiotherapy With Chemotherapy for Newly Diagnosed Average-Risk Medulloblastoma.
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Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma.
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Favorable Trisomies and ETV6-RUNX1 Predict Cure in Low-Risk B-Cell Acute Lymphoblastic Leukemia: Results From Children's Oncology Group Trial AALL0331.
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Prognostic impact of minimal residual disease at the end of consolidation in NCI standard-risk B-lymphoblastic leukemia: A report from the Children's Oncology Group.
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Comparison of CALGB 10403 (Alliance) and COG AALL0232 toxicity results in young adults with acute lymphoblastic leukemia.
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Excellent Outcomes With Reduced Frequency of Vincristine and Dexamethasone Pulses in Standard-Risk B-Lymphoblastic Leukemia: Results From Children's Oncology Group AALL0932.
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Outcomes of paediatric patients with B-cell acute lymphocytic leukaemia with ABL-class fusion in the pre-tyrosine-kinase inhibitor era: a multicentre, retrospective, cohort study.
den Boer ML, Cario G, Moorman AV, Boer JM, de Groot-Kruseman HA, Fiocco M, Escherich G, Imamura T, Yeoh A, Sutton R, Dalla-Pozza L, Kiyokawa N, Schrappe M, Roberts KG, Mullighan CG, Hunger SP, Vora A, Attarbaschi A, Zaliova M, Elitzur S, Cazzaniga G, Biondi A, Loh ML, Pieters R; Ponte di Legno Childhood ALL Working Group. den Boer ML, et al. Lancet Haematol. 2021 Jan;8(1):e55-e66. doi: 10.1016/S2352-3026(20)30353-7. Epub 2020 Dec 22. Lancet Haematol. 2021. PMID: 33357483 Free PMC article. Clinical Trial.
A prospective study of pediatric and adolescent renal cell carcinoma: A report from the Children's Oncology Group AREN0321 study.
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Children's Oncology Group AALL0434: A Phase III Randomized Clinical Trial Testing Nelarabine in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia.
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Risk-associated alterations in marrow T cells in pediatric leukemia.
Bailur JK, McCachren SS, Pendleton K, Vasquez JC, Lim HS, Duffy A, Doxie DB, Kaushal A, Foster C, DeRyckere D, Castellino S, Kemp ML, Qiu P, Dhodapkar MV, Dhodapkar KM. Bailur JK, et al. JCI Insight. 2020 Aug 20;5(16):e140179. doi: 10.1172/jci.insight.140179. JCI Insight. 2020. PMID: 32692727 Free PMC article.
Successful Outcomes of Newly Diagnosed T Lymphoblastic Lymphoma: Results From Children's Oncology Group AALL0434.
Hayashi RJ, Winter SS, Dunsmore KP, Devidas M, Chen Z, Wood BL, Hermiston ML, Teachey DT, Perkins SL, Miles RR, Raetz EA, Loh ML, Winick NJ, Carroll WL, Hunger SP, Lim MS, Gross TG, Bollard CM. Hayashi RJ, et al. J Clin Oncol. 2020 Sep 10;38(26):3062-3070. doi: 10.1200/JCO.20.00531. Epub 2020 Jun 17. J Clin Oncol. 2020. PMID: 32552472 Free PMC article. Clinical Trial.
Impact of Intrathecal Triple Therapy Versus Intrathecal Methotrexate on Disease-Free Survival for High-Risk B-Lymphoblastic Leukemia: Children's Oncology Group Study AALL1131.
Salzer WL, Burke MJ, Devidas M, Dai Y, Hardy KK, Kairalla JA, Gore L, Hilden JM, Larsen E, Rabin KR, Zweidler-McKay PA, Borowitz MJ, Wood B, Heerema NA, Carroll AJ, Winick N, Carroll WL, Raetz EA, Loh ML, Hunger SP. Salzer WL, et al. J Clin Oncol. 2020 Aug 10;38(23):2628-2638. doi: 10.1200/JCO.19.02892. Epub 2020 Jun 4. J Clin Oncol. 2020. PMID: 32496902 Free PMC article. Clinical Trial.
Results of Treatment for Patients With Multicentric or Bilaterally Predisposed Unilateral Wilms Tumor (AREN0534): A report from the Children's Oncology Group.
Ehrlich PF, Chi YY, Chintagumpala MM, Hoffer FA, Perlman EJ, Kalapurakal JA, Tornwall B, Warwick A, Shamberger RC, Khanna G, Hamilton TE, Gow KW, Paulino AC, Gratias EJ, Mullen EA, Geller JI, Grundy PE, Fernandez CV, Dome JS. Ehrlich PF, et al. Cancer. 2020 Aug 1;126(15):3516-3525. doi: 10.1002/cncr.32958. Epub 2020 May 27. Cancer. 2020. PMID: 32459384 Free PMC article. Clinical Trial.
Outcomes after late bone marrow and very early central nervous system relapse of childhood B-acute lymphoblastic leukemia: a report from the Children's Oncology Group phase III study AALL0433.
Lew G, Chen Y, Lu X, Rheingold SR, Whitlock JA, Devidas M, Hastings CA, Winick NJ, Carroll WL, Wood BL, Borowitz MJ, Pulsipher MA, Hunger SP. Lew G, et al. Haematologica. 2021 Jan 1;106(1):46-55. doi: 10.3324/haematol.2019.237230. Haematologica. 2021. PMID: 32001530 Free PMC article. Clinical Trial.
Outcome in Children With Standard-Risk B-Cell Acute Lymphoblastic Leukemia: Results of Children's Oncology Group Trial AALL0331.
Maloney KW, Devidas M, Wang C, Mattano LA, Friedmann AM, Buckley P, Borowitz MJ, Carroll AJ, Gastier-Foster JM, Heerema NA, Kadan-Lottick N, Loh ML, Matloub YH, Marshall DT, Stork LC, Raetz EA, Wood B, Hunger SP, Carroll WL, Winick NJ. Maloney KW, et al. J Clin Oncol. 2020 Feb 20;38(6):602-612. doi: 10.1200/JCO.19.01086. Epub 2019 Dec 11. J Clin Oncol. 2020. PMID: 31825704 Free PMC article. Clinical Trial.
Replication timing alterations in leukemia affect clinically relevant chromosome domains.
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