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Year Number of Results
1946 3
1947 4
1948 3
1949 3
1950 3
1951 11
1952 9
1953 6
1954 12
1955 7
1956 5
1957 14
1958 14
1959 17
1960 19
1961 19
1962 23
1963 46
1964 61
1965 70
1966 180
1967 215
1968 212
1969 198
1970 209
1971 186
1972 199
1973 231
1974 295
1975 368
1976 406
1977 601
1978 981
1979 1192
1980 15684
1981 33526
1982 34550
1983 35010
1984 36719
1985 37422
1986 38594
1987 39962
1988 41076
1989 42717
1990 44827
1991 46114
1992 46700
1993 47432
1994 48920
1995 49309
1996 49490
1997 49828
1998 50822
1999 52351
2000 54914
2001 56285
2002 59353
2003 63565
2004 71237
2005 77891
2006 86483
2007 93062
2008 103156
2009 109953
2010 119282
2011 128378
2012 132919
2013 138079
2014 139456
2015 140566
2016 135798
2017 130818
2018 133084
2019 134067
2020 145800
2021 152165
2022 137471
2023 131151
2024 35401
2025 1

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Effect of Health Service Area on Primary Care Physician Provision of Low-Value Cancer Screening.
Dindinger-Hill K, Horns J, Ambrose J, Vehawn J, Choudry M, Hunt TC, Chipman J, Haaland B, Li J, Hanson HA, O'Neil B. Dindinger-Hill K, et al. Ann Intern Med. 2024 Apr 23. doi: 10.7326/M23-1456. Online ahead of print. Ann Intern Med. 2024. PMID: 38648640
DESIGN: Retrospective study analyzing LVC rates between 2008 and 2018, leveraging physician relocation in 3-year intervals of matched physician and patient groups. SETTING: U.S. Medicare claims data. PARTICIPANTS: 8254 physicians and 56 467 patients aged 75 years or …
DESIGN: Retrospective study analyzing LVC rates between 2008 and 2018, leveraging physician relocation in 3-year intervals of matched physic …
PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self-renewal in mouse and human hematopoietic cells.
Katerndahl CDS, Rogers ORS, Day RB, Xu Z, Helton NM, Ramakrishnan SM, Miller CA, Ley TJ. Katerndahl CDS, et al. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2317690121. doi: 10.1073/pnas.2317690121. Epub 2024 Apr 22. Proc Natl Acad Sci U S A. 2024. PMID: 38648485
We defined the genomic binding sites of PML::RARA in primary mouse and human hematopoietic progenitor cells with V5-tagged PML::RARA, using anti-V5-PML::RARA chromatin immunoprecipitation sequencing and CUT&RUN approaches. ...
We defined the genomic binding sites of PML::RARA in primary mouse and human hematopoietic progenitor cells with V5-tagged PML::RARA, …
Changes in well-being among socially isolated older people during the COVID-19 pandemic: An outcome-wide analysis.
Kung CSJ, Steptoe A. Kung CSJ, et al. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2308697121. doi: 10.1073/pnas.2308697121. Epub 2024 Apr 22. Proc Natl Acad Sci U S A. 2024. PMID: 38648476
We apply an outcome-wide longitudinal design on 4,636 participants (mean age 66.8 y) from the English Longitudinal Study of Ageing, observed in 2018/19 and early (June/July 2020) and later (November/December 2020) in the pandemic. Social isolation is defined using an index …
We apply an outcome-wide longitudinal design on 4,636 participants (mean age 66.8 y) from the English Longitudinal Study of Ageing, observed …
Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury.
Varadharajan V, Ramachandiran I, Massey WJ, Jain R, Banerjee R, Horak AJ, McMullen MR, Huang E, Bellar A, Lorkowski SW, Gulshan K, Helsley RN, James I, Pathak V, Dasarathy J, Welch N, Dasarathy S, Streem D, Reizes O, Allende DS, Smith JD, Simcox J, Nagy LE, Brown JM. Varadharajan V, et al. Elife. 2024 Apr 22;12:RP92243. doi: 10.7554/eLife.92243. Elife. 2024. PMID: 38648183
Translating a motivational interviewing intervention for childhood cancer survivors into an eHealth tool: A user-centered design process.
Ruiz S, Ackermann N, Maki J, Carcone AI, Hudson MM, Ehrhardt MJ, Cloakey D, DuChateau D, Griffith SA, Johnson A, Phillips A, Waters EA. Ruiz S, et al. Transl Behav Med. 2024 Apr 22:ibae014. doi: 10.1093/tbm/ibae014. Online ahead of print. Transl Behav Med. 2024. PMID: 38648182
This translation process shows that continued in-depth engagement of community advisors and iterative testing can improve the applicability of an eHealth to survivors' lived experiences and social contexts. Childhood cancer survivors have a higher-than-average risk for dev …
This translation process shows that continued in-depth engagement of community advisors and iterative testing can improve the applicability …
Changes in the Appropriateness of US Outpatient Antibiotic Prescribing After the Coronavirus Disease 2019 Outbreak: An Interrupted Time Series Analysis of 2016-2021 Data.
Chua KP, Fischer MA, Rahman M, Linder JA. Chua KP, et al. Clin Infect Dis. 2024 Apr 22:ciae135. doi: 10.1093/cid/ciae135. Online ahead of print. Clin Infect Dis. 2024. PMID: 38648159
BACKGROUND: No national study has evaluated changes in the appropriateness of US outpatient antibiotic prescribing across all conditions and age groups after the coronavirus disease 2019 (COVID-19) outbreak in March 2020. METHODS: This was an interrupted time series analys …
BACKGROUND: No national study has evaluated changes in the appropriateness of US outpatient antibiotic prescribing across all conditi …
Antipsychotic-induced epigenomic reorganization in frontal cortex of individuals with schizophrenia.
Zhu B, Ainsworth RI, Wang Z, Liu Z, Sierra S, Deng C, Callado LF, Meana JJ, Wang W, Lu C, González-Maeso J. Zhu B, et al. Elife. 2024 Apr 22;12:RP92393. doi: 10.7554/eLife.92393. Elife. 2024. PMID: 38648100
By analyzing the AF and AT cohorts separately, we identified schizophrenia-associated alterations in specific transcription factors, their regulatees, and epigenomic and transcriptomic features that were reversed by antipsychotic treatment; as well as those that represented a con …
By analyzing the AF and AT cohorts separately, we identified schizophrenia-associated alterations in specific transcription factors, their r …
Association of red blood cell distribution width to albumin ratio with prognosis in stroke patients.
Eyiol A, Ertekin B. Eyiol A, et al. Biomark Med. 2024 Apr 22. doi: 10.2217/bmm-2023-0460. Online ahead of print. Biomark Med. 2024. PMID: 38648096
Methods: One hundred twenty-seven patients with AIS were prospectively analyzed. The NIH Stroke Scale was used to determine stroke severity. RAR was compared between severe and nonsevere patients. ...According to receiver operating characteristic analysis, RAR alone predic …
Methods: One hundred twenty-seven patients with AIS were prospectively analyzed. The NIH Stroke Scale was used to determine stroke se …
Cervical Spine Surgery Following COVID-19 Infection: When is it Safe to Proceed?
Chan JP, Hoang H, Wu HH, Park DY, Lee YP, Bhatia N, Hashmi SZ; N3C Consortium. Chan JP, et al. Clin Spine Surg. 2024 Apr 19. doi: 10.1097/BSD.0000000000001609. Online ahead of print. Clin Spine Surg. 2024. PMID: 38648080
STUDY DESIGN: Retrospective. OBJECTIVE: We utilized the NIH National COVID Cohort Collaborative (N3C) database to characterize the risk profile of patients undergoing spine surgery during multiple time windows following the COVID-19 infection. SUMMARY OF BACKGROUND …
STUDY DESIGN: Retrospective. OBJECTIVE: We utilized the NIH National COVID Cohort Collaborative (N3C) database to characterize …
Perceived Stress, Blood Biomarkers, and Cognitive Functioning in Older Adults.
Desai P, Ng TKS, Krueger KR, Wilson RS, Evans DA, Rajan KB. Desai P, et al. Psychosom Med. 2024 Apr 16. doi: 10.1097/PSY.0000000000001317. Online ahead of print. Psychosom Med. 2024. PMID: 38648023
METHODS: This study consists of 1,118 older adult participants from the Chicago Health and Aging Project (CHAP) (60% Black participants and 63% female participants). ...
METHODS: This study consists of 1,118 older adult participants from the Chicago Health and Aging Project (CHAP) (60% Black participan …
The association of pre-cancer diagnosis cardiovascular risk factors with memory aging after a cancer diagnosis, overall and by race/ethnicity.
Westrick AC, Zhu P, Friese CR, Langa KM, Kobayashi LC. Westrick AC, et al. J Cancer Surviv. 2024 Apr 22. doi: 10.1007/s11764-024-01593-4. Online ahead of print. J Cancer Surviv. 2024. PMID: 38647590
METHODS: Incident cancer diagnoses and memory (immediate and delayed recall) were assessed biennially in the US Health and Retirement Study (N = 5,736, 1998-2018). CVRFs measured at the wave prior to a cancer diagnosis included self-reported cigarette smoking, obesity, dia …
METHODS: Incident cancer diagnoses and memory (immediate and delayed recall) were assessed biennially in the US Health and Retirement …
Systemic inflammation and delirium during critical illness.
Brummel NE, Hughes CG, McNeil JB, Pandharipande PP, Thompson JL, Orun OM, Raman R, Ware LB, Bernard GR, Harrison FE, Ely EW, Girard TD. Brummel NE, et al. Intensive Care Med. 2024 Apr 22. doi: 10.1007/s00134-024-07388-6. Online ahead of print. Intensive Care Med. 2024. PMID: 38647548
Can behaviorally inhibited preschoolers make friends?
Fleece H, Wagner NJ, Chronis-Tuscano A, Smith KA, Novick DR, Druskin LR, Shakiba N, Danko CM, Rubin KH. Fleece H, et al. Dev Psychol. 2024 Apr 22. doi: 10.1037/dev0001742. Online ahead of print. Dev Psychol. 2024. PMID: 38647467
Probit regression analyses revealed that parent ratings of BI among unfamiliar peers and teacher ratings of children's social anxiety before the intervention were associated with a decreased probability of making a friend. ...
Probit regression analyses revealed that parent ratings of BI among unfamiliar peers and teacher ratings of children's social anxiety …
Sex-specific associations between childhood trauma and adult systemic inflammation in daily life.
Natale BN, Koffer RE, Fairlie SE, Dickman KD, Walsh CP, Marsland AL, Kamarck TW. Natale BN, et al. Health Psychol. 2024 Apr 22. doi: 10.1037/hea0001382. Online ahead of print. Health Psychol. 2024. PMID: 38647448
OBJECTIVE: Childhood trauma may contribute to lifelong health through chronic systemic inflammation. However, associations between childhood trauma and inflammation are mixed, indicating that distinct types of childhood trauma may relate to inflammation differently. ...
OBJECTIVE: Childhood trauma may contribute to lifelong health through chronic systemic inflammation. However, associations between ch …
Phenotypic consequences of GBA1 pathological variant R463C (p.R502C).
Ryan E, Nishimura S, Lopez G, Tayebi N, Sidransky E. Ryan E, et al. Am J Med Genet A. 2024 Apr 22:e63630. doi: 10.1002/ajmg.a.63630. Online ahead of print. Am J Med Genet A. 2024. PMID: 38647370
To better characterize its different clinical presentations, we examined the records of 25 current and historical patients evaluated at the National Institutes of Health. Nine patients were classified as GD1, 14 were classified as GD3, and two had an ambiguou …
To better characterize its different clinical presentations, we examined the records of 25 current and historical patients evaluated at the …
The beneficial effect of α-lipoic acid on spinal cord injury repair in rats is mediated through inhibition of oxidative stress: A transcriptomic analysis.
Bian MM, Xu YM, Zhang L, Yan HZ, Gao JX, Fu GQ, Wang YY, Lü HZ. Bian MM, et al. J Spinal Cord Med. 2024 Apr 22:1-14. doi: 10.1080/10790268.2024.2342058. Online ahead of print. J Spinal Cord Med. 2024. PMID: 38647358
The sequence data from this study has been deposited into Sequence Read Archive (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE242507). CONCLUSION: Overall, the findings of this study confirmed the beneficial effects of ALA on recovery in SCI rats through transcrip …
The sequence data from this study has been deposited into Sequence Read Archive (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=G …
Screening for diabetes distress and depression in routine clinical care for youth with type 1 diabetes.
Albright D, Wardell J, Harrison A, Mizokami-Stout K, Hirschfeld E, Garrity A, Thomas I, Lee J. Albright D, et al. J Pediatr Psychol. 2024 Apr 22:jsae016. doi: 10.1093/jpepsy/jsae016. Online ahead of print. J Pediatr Psychol. 2024. PMID: 38647266
METHODS: In a pediatric diabetes clinic, 716 youth (ages 12-21 years) completed measures of diabetes distress (Problem Areas in Diabetes-Teen [PAID-T]), a single-item of diabetes distress, and depression (Patient Health Questionnaire [PHQ-9]) as part of standard care. Elec …
METHODS: In a pediatric diabetes clinic, 716 youth (ages 12-21 years) completed measures of diabetes distress (Problem Areas in Diabetes-Tee …
Breakthrough Mpox outbreak investigation, the delicate balance between host immune response and viral immune escape.
Moretti M, Meuwissen A, Rezende AM, Zange S, Van Nedervelde E, de Block T, Vercauteren K, Demuyser T, Allard SD. Moretti M, et al. Sex Transm Dis. 2024 Apr 19. doi: 10.1097/OLQ.0000000000001974. Online ahead of print. Sex Transm Dis. 2024. PMID: 38647249
Whole genome sequencing (WGS) was carried out and compared to the reference sequence ON563414.3 (https://www.ncbi.nlm.nih.gov/nuccore/ON563414.3/). RESULTS: Three individuals vaccinated with modified vaccinia Ankara-Bavaria Nordic contracted Mpox following one sexual inter …
Whole genome sequencing (WGS) was carried out and compared to the reference sequence ON563414.3 (https://www.ncbi.nlm.nih.gov/nuccore …
Barriers to dental utilization among Medicaid-enrolled young children from primary care practices in Northeast Ohio.
Selvaraj D, Agarwal N, Albert JM, Nelson S. Selvaraj D, et al. Community Dent Oral Epidemiol. 2024 Apr 22. doi: 10.1111/cdoe.12964. Online ahead of print. Community Dent Oral Epidemiol. 2024. PMID: 38647184
The baseline data were then linked to dental Medicaid claims data (categorized as any dental visit, volume, and type in the past 12 months) and ICD-10 codes from the child's EHR data (individual-level) together with Dental Health Provider Shortage Area (HPSA) status and Ar …
The baseline data were then linked to dental Medicaid claims data (categorized as any dental visit, volume, and type in the past 12 months) …
Comprehensive profiling of L1 retrotransposons in mouse.
Zhang X, Celic I, Mitchell H, Stuckert S, Vedula L, Han JS. Zhang X, et al. Nucleic Acids Res. 2024 Apr 22:gkae273. doi: 10.1093/nar/gkae273. Online ahead of print. Nucleic Acids Res. 2024. PMID: 38647072
Although L1s are typically silenced in most normal tissues, elevated L1 expression is associated with a variety of conditions, including cancer, aging, infertility and neurological disease. These associations have raised interest in the mapping of human endogenous de novo …
Although L1s are typically silenced in most normal tissues, elevated L1 expression is associated with a variety of conditions, including can …
The discovery of novel noncoding RNAs in 50 bacterial genomes.
Narunsky A, Higgs GA, Torres BM, Yu D, de Andrade GB, Kavita K, Breaker RR. Narunsky A, et al. Nucleic Acids Res. 2024 Apr 22:gkae248. doi: 10.1093/nar/gkae248. Online ahead of print. Nucleic Acids Res. 2024. PMID: 38647067
Genome-wide screening and functional validation of methylation barriers near promoters.
Shu J, Jelinek J, Chen H, Zhang Y, Qin T, Li M, Liu L, Issa JJ. Shu J, et al. Nucleic Acids Res. 2024 Apr 22:gkae302. doi: 10.1093/nar/gkae302. Online ahead of print. Nucleic Acids Res. 2024. PMID: 38647050
Aberrant hypermethylation of these CpG islands has been associated with the development of various human diseases. Although local genetic elements have been speculated to play a role in protecting promoters from methylation, only a limited number of methylation barriers ha …
Aberrant hypermethylation of these CpG islands has been associated with the development of various human diseases. Although local gen …
Whole-brain deuterium metabolic imaging via concentric ring trajectory readout enables assessment of regional variations in neuronal glucose metabolism.
Niess F, Strasser B, Hingerl L, Bader V, Frese S, Clarke WT, Duguid A, Niess E, Motyka S, Krššák M, Trattnig S, Scherer T, Lanzenberger R, Bogner W. Niess F, et al. Hum Brain Mapp. 2024 Apr 15;45(6):e26686. doi: 10.1002/hbm.26686. Hum Brain Mapp. 2024. PMID: 38647048
Deuterium metabolic imaging (DMI) is an emerging magnetic resonance technique, for non-invasive mapping of human brain glucose metabolism following oral or intravenous administration of deuterium-labeled glucose. ...
Deuterium metabolic imaging (DMI) is an emerging magnetic resonance technique, for non-invasive mapping of human brain glucose metabo …
MutationExplorer: a webserver for mutation of proteins and 3D visualization of energetic impacts.
Philipp M, Moth CW, Ristic N, Tiemann JKS, Seufert F, Panfilova A, Meiler J, Hildebrand PW, Stein A, Wiegreffe D, Staritzbichler R. Philipp M, et al. Nucleic Acids Res. 2024 Apr 22:gkae301. doi: 10.1093/nar/gkae301. Online ahead of print. Nucleic Acids Res. 2024. PMID: 38647044
Previously the purview of desktop applications, such an upload can back-mutate PDB structures to wildtype sequence in a single step. Another supported variation source is human single nucelotide polymorphisms (SNPs), genomic coordinates input in VCF format. ...
Previously the purview of desktop applications, such an upload can back-mutate PDB structures to wildtype sequence in a single step. Another …
Regulation of CNS pathology by Serpina3n/SERPINA3: The knowns and the puzzles.
Zhu M, Lan Z, Park J, Gong S, Wang Y, Guo F. Zhu M, et al. Neuropathol Appl Neurobiol. 2024 Apr;50(2):e12980. doi: 10.1111/nan.12980. Neuropathol Appl Neurobiol. 2024. PMID: 38647003 Review.
Serine protease inhibitor (Serpin) clade A member 3n (Serpina3n), and its human orthologue SERPINA3, is an acute-phase inflammatory glycoprotein secreted primarily by the liver into the bloodstream in response to systemic inflammation. ...
Serine protease inhibitor (Serpin) clade A member 3n (Serpina3n), and its human orthologue SERPINA3, is an acute-phase inflammatory g …
Single proxy control.
Park C, Richardson DB, Tchetgen Tchetgen EJ. Park C, et al. Biometrics. 2024 Mar 27;80(2):ujae027. doi: 10.1093/biomtc/ujae027. Biometrics. 2024. PMID: 38646999
Coma in adult cerebral venous thrombosis: The BEAST study.
Ranjan R, Ken-Dror G, Martinelli I, Grandone E, Hiltunen S, Lindgren E, Margaglione M, Duchez VLC, Triquenot Bagan A, Zedde M, Giannini N, Ruigrok YM, Worrall BB, Majersik JJ, Putaala J, Haapaniemi E, Zuurbier SM, Brouwer MC, Passamonti SM, Abbattista M, Bucciarelli P, Lemmens R, Pappalardo E, Costa P, Colombi M, Aguiar de Sousa D, Rodrigues S, Canhão P, Tkach A, Santacroce R, Favuzzi G, Arauz A, Colaizzo D, Spengos K, Hodge A, Ditta R, Pezzini A, Coutinho JM, Thijs V, Jood K, Tatlisumak T, Ferro JM, Sharma P. Ranjan R, et al. Eur J Neurol. 2024 Apr 22:e16311. doi: 10.1111/ene.16311. Online ahead of print. Eur J Neurol. 2024. PMID: 38646961
Optimized Workflow for Proteomics and Phosphoproteomics With Limited Tissue Samples.
Hu M, Wang Y. Hu M, et al. Curr Protoc. 2024 Apr;4(4):e1028. doi: 10.1002/cpz1.1028. Curr Protoc. 2024. PMID: 38646944
This innovative workflow not only overcomes the challenges posed by limited sample sizes but also establishes a new benchmark for precision and efficiency in proteomic investigations. Published 2024. This article is a U.S. Government work and is in the public domain …
This innovative workflow not only overcomes the challenges posed by limited sample sizes but also establishes a new benchmark for precision …
Sarcopenia, adiposity and large discordance between cystatin C and creatinine-based estimated glomerular filtration rate in patients with cancer.
Hanna PE, Ouyang T, Tahir I, Katz-Agranov N, Wang Q, Mantz L, Strohbehn I, Moreno D, Harden D, Dinulos JE, Cosar D, Seethapathy H, Gainor JF, Shah SJ, Gupta S, Leaf DE, Fintelmann FJ, Sise ME. Hanna PE, et al. J Cachexia Sarcopenia Muscle. 2024 Apr 22. doi: 10.1002/jcsm.13469. Online ahead of print. J Cachexia Sarcopenia Muscle. 2024. PMID: 38646842
Accelerated sarcopenia precedes learning and memory impairments in the P301S mouse model of tauopathies and Alzheimer's disease.
Longo S, Messi ML, Wang ZM, Meeker W, Delbono O. Longo S, et al. J Cachexia Sarcopenia Muscle. 2024 Apr 22. doi: 10.1002/jcsm.13482. Online ahead of print. J Cachexia Sarcopenia Muscle. 2024. PMID: 38646816
BACKGROUND: Alzheimer's disease (AD) impairs cognitive functions and peripheral systems, including skeletal muscles. The PS19 mouse, expressing the human tau P301S mutation, shows cognitive and muscular pathologies, reflecting the central and peripheral atrophy seen in AD. …
BACKGROUND: Alzheimer's disease (AD) impairs cognitive functions and peripheral systems, including skeletal muscles. The PS19 mouse, express …
Immediate Lymphatic Reconstruction with Vascularized Omentum Lymph Node Transplant: Reducing the Risk of Both Painful Contracture and Lymphedema.
Brown S, Kokosis G, Graziano FD, Haran O, Smith-Montes E, Zivanovic O, Ariyan CE, Coit DG, Coriddi M, Mehrara BJ, Dayan JH. Brown S, et al. Plast Reconstr Surg Glob Open. 2024 Apr 19;12(4):e5747. doi: 10.1097/GOX.0000000000005747. eCollection 2024 Apr. Plast Reconstr Surg Glob Open. 2024. PMID: 38645629 Free PMC article.
Clinical prediction of GBA carrier status in Parkinson's disease.
Greenberg J, Astudillo K, Frucht SJ, Flinker A, Riboldi GM. Greenberg J, et al. Clin Park Relat Disord. 2024 Apr 11;10:100251. doi: 10.1016/j.prdoa.2024.100251. eCollection 2024. Clin Park Relat Disord. 2024. PMID: 38645305 Free PMC article.
Design of the COMEBACK and BACKHOME Studies, Longitudinal Cohorts for Comprehensive Deep Phenotyping of Adults with Chronic Low-Back Pain (cLBP): a part of the BACPAC Research Program.
Hue TF, Lotz JC, Zheng P, Black DM, Bailey J, Ewing SK, Fields AJ, Mehling W, Scheffler A, Strigo I, Petterson T, Wu LA, O'Neill C; UCSF REACH Center; CoRe CEnter for PAtient-Centric Mechanistic PHenotyping in Chronic Low Back Pain. Hue TF, et al. medRxiv [Preprint]. 2024 Apr 12:2024.04.09.24305574. doi: 10.1101/2024.04.09.24305574. medRxiv. 2024. PMID: 38645207 Free PMC article. Preprint.
OBJECTIVE: The University of California, San Francisco (UCSF) Core Center for Patient-centric, Mechanistic Phenotyping in Chronic Low Back Pain (REACH) is one of the three NIH Back Pain Consortium (BACPAC) Research Programs Mechanistic Research Centers (MRCs). ...While, th …
OBJECTIVE: The University of California, San Francisco (UCSF) Core Center for Patient-centric, Mechanistic Phenotyping in Chronic Low Back P …
DRI Triton SS-OCT applied to detect choroidal nodules in paediatric patients affected by NF1.
Fresno Cañada C, Gispets Parcerisas J, Del Prado Sánchez C, Puigventós Rosanas E, Perez-Jaume S, Salvador H, Llorca Cardeñosa A, Prat Bartomeu J. Fresno Cañada C, et al. Heliyon. 2024 Apr 9;10(8):e29263. doi: 10.1016/j.heliyon.2024.e29263. eCollection 2024 Apr 30. Heliyon. 2024. PMID: 38644819 Free PMC article.
MATERIAL AND METHODS: We included 417 eyes from 210 patients, 377 - from 190 patients diagnosed with NF1 according to the criteria established by the National Institutes of Health Consensus Development Conference (NIH) and 40 from 20 healthy patients a …
MATERIAL AND METHODS: We included 417 eyes from 210 patients, 377 - from 190 patients diagnosed with NF1 according to the criteria establish …
Cortical microinfarcts in adults with Down syndrome assessed with 3T-MRI.
Aranha MR, Montal V, van den Brink H, Pegueroles J, Carmona-Iragui M, Videla L, Maure Blesa L, Benejam B, Arranz J, Valldeneu S, Barroeta I, Fernández S, Ribas L, Alcolea D, González-Ortiz S, Bargalló N, Biessels GJ, Blesa R, Lleó A, Coutinho AM, Leite CC, Bejanin A, Fortea J. Aranha MR, et al. Alzheimers Dement. 2024 Apr 21. doi: 10.1002/alz.13797. Online ahead of print. Alzheimers Dement. 2024. PMID: 38644660
Impact of sociodemographic factors, stress, and communication on health-related quality of life in survivors of pediatric cancer.
Patterson V, Olsavsky A, Garcia D, Sutherland-Foggio M, Vannatta K, Prussien KV, Bemis H, Compas BE, Gerhardt CA. Patterson V, et al. Pediatr Blood Cancer. 2024 Apr 21:e31001. doi: 10.1002/pbc.31001. Online ahead of print. Pediatr Blood Cancer. 2024. PMID: 38644596
BACKGROUND: While most research has largely focused on medical risks associated with reduced health-related quality of life (HRQOL) in survivors, sociodemographic and family factors may also play a role. ...Such interventions may be complimentary to efforts targeting the k …
BACKGROUND: While most research has largely focused on medical risks associated with reduced health-related quality of life (HRQOL) i …
Injectable bioactive poly(propylene fumarate) and polycaprolactone based click chemistry bone cement for spinal fusion in rabbits.
Liu X, Astudillo Potes MD, Serdiuk V, Dashtdar B, Schreiber AC, Rezaei A, Lee Miller A 2nd, Hamouda AM, Shafi M, Elder BD, Lu L. Liu X, et al. J Biomed Mater Res A. 2024 Apr 21. doi: 10.1002/jbm.a.37725. Online ahead of print. J Biomed Mater Res A. 2024. PMID: 38644548
Furthermore, nano-hydroxyapatite (nHA) and microspheres carrying recombinant human bone morphogenetic protein-2 (rhBMP-2) and recombinant human vascular endothelial growth factor (rhVEGF) were used to make the cement bioactive for vascular induction and osteointegra …
Furthermore, nano-hydroxyapatite (nHA) and microspheres carrying recombinant human bone morphogenetic protein-2 (rhBMP-2) and recombi …
Pulmonary dimorphic fungal infections among HIV/AIDS non-TB patients with chronic cough in Kampala, Uganda.
Kiconco P, Achan B, Sanya M, Najjingo I, Okeng A, Bwanga F. Kiconco P, et al. Mycoses. 2024 Apr;67(4):e13726. doi: 10.1111/myc.13726. Mycoses. 2024. PMID: 38644511
OBJECTIVE: To determine the prevalence of pulmonary dimorphic fungal infections among HIV/AIDS patients with non-TB chronic cough at Mulago National Referral and Teaching Hospital in Kampala, Uganda. METHODS: Sputum samples were collected from 175 consented HIV/AIDS patien …
OBJECTIVE: To determine the prevalence of pulmonary dimorphic fungal infections among HIV/AIDS patients with non-TB chronic cough at Mulago …
Impact of the COVID-19 pandemic on utilization and cost for care of pediatric and young adult ALL.
Hoover A, Watson D, Reimche P, Tanner L, Gilchrist L, Finch M, Messinger YH, Turcotte LM. Hoover A, et al. BMC Res Notes. 2024 Apr 22;17(1):112. doi: 10.1186/s13104-024-06768-x. BMC Res Notes. 2024. PMID: 38644484
This provides a valuable benchmark as we further examine the factors that influence the pandemic's impact on health equity and access to care, especially in vulnerable pediatric and young adult populations. ...
This provides a valuable benchmark as we further examine the factors that influence the pandemic's impact on health equity and access …
Efficacy and safety of bendamustine for lymphodepletion before lisocabtagene maraleucel.
Ghilardi G, Paruzzo L, Patel V, Svoboda J, Chong ER, Fardella E, Chong EA, Gabrielli G, Nasta SD, Landsburg DJ, Carter J, Pajarillo R, Barta SK, White G, Weber E, Napier E, Porter DL, Garfall AL, Schuster SJ, Ruella M. Ghilardi G, et al. J Hematol Oncol. 2024 Apr 22;17(1):19. doi: 10.1186/s13045-024-01542-9. J Hematol Oncol. 2024. PMID: 38644469
Compliance with web content accessibility guidelines in ophthalmology social media posts.
Sharma M, Huertas L, Shah S, Gil A, Bitrian E, Chang TC. Sharma M, et al. Sci Rep. 2024 Apr 21;14(1):9142. doi: 10.1038/s41598-024-59838-2. Sci Rep. 2024. PMID: 38644414
A total of 100 social media posts were sampled from ten ophthalmology patient education social media pages and ten non-ophthalmology (cardiopulmonary) pages as the comparison group. ...Because social media is highly visual, reduced compliance to WCAG may crea …
A total of 100 social media posts were sampled from ten ophthalmology patient education social media pages and ten non-ophthal …
Characterization of a novel mouse platelet transfusion model.
Gordy D, Swayne T, Berry GJ, Thomas TA, Hudson KE, Stone EF. Gordy D, et al. Vox Sang. 2024 Apr 21. doi: 10.1111/vox.13642. Online ahead of print. Vox Sang. 2024. PMID: 38643983
CONCLUSION: We developed mouse platelets for transfusion analogous to human platelet units using a modified PRP collection protocol with maximum storage of 1 day for an 'old' unit. ...
CONCLUSION: We developed mouse platelets for transfusion analogous to human platelet units using a modified PRP collection protocol w …
Estimating vaccine efficacy during open-label follow-up of COVID-19 vaccine trials based on population-level surveillance data.
Moore M, Zhu Y, Hirsch I, White T, Reiner RC, Barber RM, Pigott D, Collins JK, Santoni S, Sobieszczyk ME, Janes H. Moore M, et al. Epidemics. 2024 Apr 15;47:100768. doi: 10.1016/j.epidem.2024.100768. Online ahead of print. Epidemics. 2024. PMID: 38643547
While rapid development and roll out of COVID-19 vaccines is necessary in a pandemic, the process limits the ability of clinical trials to assess longer-term vaccine efficacy. We leveraged COVID-19 surveillance data in the U.S. to evaluate vaccine efficacy in U …
While rapid development and roll out of COVID-19 vaccines is necessary in a pandemic, the process limits the ability of clinical trials to a …
Tear Protein Markers for Diabetic Retinopathy and Diabetic Macular Edema - Towards an Early Diagnosis and Better Prognosis.
Sharma S, Belenje A, Takkar B, Narula R, Rathi VM, Tyagi M, Rani PK, Narayanan R, Kaur I. Sharma S, et al. Semin Ophthalmol. 2024 Apr 20:1-11. doi: 10.1080/08820538.2024.2342266. Online ahead of print. Semin Ophthalmol. 2024. PMID: 38643349 Review.
This creates a massive demand for development of such biomarkers that help detect disease in its earlier stages. METHODS: PUBMED (https://pubmed.ncbi.nlm.nih.gov/) was searched for articles relevant to the topic published till November 2023. ...
This creates a massive demand for development of such biomarkers that help detect disease in its earlier stages. METHODS: PUBMED (https://pu …
Evaluation of markers of immunity in different metastatic immune microenvironments suggests more suppression within breast to liver metastases in breast cancer.
Hsu R, Al-Zubeidy B, Flores D, Nazarian A, Baugh A, Gonzalez E, Castanon S, Xiu J, Kang I, Spicer D, Lenz HJ, Dara L, Ademuyiwa FO, Korn WM, Irshad S, Chan IS, Roussos Torres ET. Hsu R, et al. Breast Cancer Res Treat. 2024 Apr 20. doi: 10.1007/s10549-024-07295-w. Online ahead of print. Breast Cancer Res Treat. 2024. PMID: 38643348
Leukemia circulation kinetics revealed through blood exchange method.
Miller AB, Rodriguez FH, Langenbucher A, Lin L, Bray C, Duquette S, Zhang Y, Goulet D, Lane AA, Weinstock DM, Hemann MT, Manalis SR. Miller AB, et al. Commun Biol. 2024 Apr 20;7(1):483. doi: 10.1038/s42003-024-06181-x. Commun Biol. 2024. PMID: 38643279 Free PMC article.
Analysis of long-range chromatin contacts, compartments and looping between mouse embryonic stem cells, lens epithelium and lens fibers.
Camerino M, Chang W, Cvekl A. Camerino M, et al. Epigenetics Chromatin. 2024 Apr 20;17(1):10. doi: 10.1186/s13072-024-00533-x. Epigenetics Chromatin. 2024. PMID: 38643244 Free PMC article.
Major differences in TADs and loops are illustrated at the ~ 500 kb Pax6 locus, encoding the critical lens regulatory transcription factor and within a larger ~ 15 Mb WAGR locus, containing Pax6 and other loci linked to human congenital diseases. Lens and ES cell Hi-C data …
Major differences in TADs and loops are illustrated at the ~ 500 kb Pax6 locus, encoding the critical lens regulatory transcription factor a …
Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia.
Rosenthal ZC, Fass DM, Payne NC, She A, Patnaik D, Hennig KM, Tesla R, Werthmann GC, Guhl C, Reis SA, Wang X, Chen Y, Placzek M, Williams NS, Hooker J, Herz J, Mazitschek R, Haggarty SJ. Rosenthal ZC, et al. Sci Rep. 2024 Apr 20;14(1):9064. doi: 10.1038/s41598-024-59110-7. Sci Rep. 2024. PMID: 38643236 Free PMC article.
Here, we show that epigenetic modulation through bromodomain and extra-terminal domain (BET) inhibitors (BETi) potently enhance PGRN protein levels, both intracellularly and secreted forms, in human central nervous system (CNS)-relevant cell types, including in microglia-l …
Here, we show that epigenetic modulation through bromodomain and extra-terminal domain (BET) inhibitors (BETi) potently enhance PGRN protein …
Diet changes due to urbanization in South Africa are linked to microbiome and metabolome signatures of Westernization and colorectal cancer.
Ramaboli MC, Ocvirk S, Khan Mirzaei M, Eberhart BL, Valdivia-Garcia M, Metwaly A, Neuhaus K, Barker G, Ru J, Nesengani LT, Mahdi-Joest D, Wilson AS, Joni SK, Layman DC, Zheng J, Mandal R, Chen Q, Perez MR, Fortuin S, Gaunt B, Wishart D, Methé B, Haller D, Li JV, Deng L, Swart R, O'Keefe SJD. Ramaboli MC, et al. Nat Commun. 2024 Apr 20;15(1):3379. doi: 10.1038/s41467-024-46265-0. Nat Commun. 2024. PMID: 38643180 Free PMC article.
Metabolic and inflammatory perturbation of diabetes associated gut dysbiosis in people living with and without HIV infection.
Luo K, Peters BA, Moon JY, Xue X, Wang Z, Usyk M, Hanna DB, Landay AL, Schneider MF, Gustafson D, Weber KM, French A, Sharma A, Anastos K, Wang T, Brown T, Clish CB, Kaplan RC, Knight R, Burk RD, Qi Q. Luo K, et al. Genome Med. 2024 Apr 20;16(1):59. doi: 10.1186/s13073-024-01336-1. Genome Med. 2024. PMID: 38643166 Free PMC article.
Racial and ethnic disparities in access to community-based perinatal mental health programs: results from a cross-sectional survey.
Rokicki S, Patel M, Suplee PD, D'Oria R. Rokicki S, et al. BMC Public Health. 2024 Apr 20;24(1):1094. doi: 10.1186/s12889-024-18517-7. BMC Public Health. 2024. PMID: 38643069 Free PMC article.
BACKGROUND: Perinatal mental health is a major public health problem that disproportionately affects people from racial and ethnic minority groups. ...Yet, little is known about racial and ethnic disparities in accessibility and utilization of community-based perina …
BACKGROUND: Perinatal mental health is a major public health problem that disproportionately affects people from racial and et …
Funding Bias in Shoulder Arthroplasty Research.
Haislup BD, Gupta S, Fleisher I, Murthi AM, Wright MA. Haislup BD, et al. J Shoulder Elbow Surg. 2024 Apr 18:S1058-2746(24)00264-7. doi: 10.1016/j.jse.2024.03.016. Online ahead of print. J Shoulder Elbow Surg. 2024. PMID: 38642875 Review.
A neutral result was defined as one in which the null hypothesis was confirmed. Article funding type, subcategorized as National Institute of Health (NIH) funding or industry funding was recorded. ...
A neutral result was defined as one in which the null hypothesis was confirmed. Article funding type, subcategorized as National Inst …
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Diseases and Injuries Collaborators. GBD 2021 Diseases and Injuries Collaborators. Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print. Lancet. 2024. PMID: 38642570
It can also facilitate more rigorous monitoring of progress towards national and international health targets, such as the Sustainable Development Goals. ...INTERPRETATION: Putting the COVID-19 pandemic in the context of a mutually exclusive and collectively exhaust …
It can also facilitate more rigorous monitoring of progress towards national and international health targets, such as the Sus …
Diet and physical activity behaviors: how are they related to illness perceptions, coping, and health-related quality of life in young people with hereditary cancer syndromes?
Rising CJ, Huelsnitz CO, Shepherd RF, Klein WMP, Sleight AG, Wilsnack C, Boyd P, Feldman AE, Khincha PP, Werner-Lin A. Rising CJ, et al. J Behav Med. 2024 Apr 20. doi: 10.1007/s10865-024-00489-z. Online ahead of print. J Behav Med. 2024. PMID: 38642305
Examining these health behaviors among young people with high lifetime genetic cancer risk may provide important insights to guide future behavioral interventions that aim to improve health-related quality of life (HRQOL). ...Greater reported physical activity was a …
Examining these health behaviors among young people with high lifetime genetic cancer risk may provide important insights to guide fu …
The Environment and Headache: a Narrative Review.
Elser H, Kruse CFG, Schwartz BS, Casey JA. Elser H, et al. Curr Environ Health Rep. 2024 Apr 20. doi: 10.1007/s40572-024-00449-4. Online ahead of print. Curr Environ Health Rep. 2024. PMID: 38642284 Review.
Characteristics of Received HIV Prevention Advocacy from Persons Living with HIV in Uganda, and Associations with HIV Testing and Condom Use Among Social Network Members.
Wagner GJ, Bogart LM, Matovu JKB, Okoboi S, Gwokyalya V, Klein DJ, Ninsiima S, Green HD. Wagner GJ, et al. AIDS Behav. 2024 Apr 20. doi: 10.1007/s10461-024-04347-6. Online ahead of print. AIDS Behav. 2024. PMID: 38642213
With baseline data from a controlled trial of an advocacy training intervention, we studied characteristics of HIV prevention advocacy received among 599 social network members of persons living with HIV in Uganda and the association of these characteristics with the so …
With baseline data from a controlled trial of an advocacy training intervention, we studied characteristics of HIV prevention advocacy recei …
A rat model of operant negative reinforcement in opioid-dependent males and females.
Chow JJ, Pitts KM, Chabot JM, Ito R, Shaham Y. Chow JJ, et al. Psychopharmacology (Berl). 2024 Apr 20. doi: 10.1007/s00213-024-06594-w. Online ahead of print. Psychopharmacology (Berl). 2024. PMID: 38642101
RATIONALE AND OBJECTIVE: Avoidance of opioid withdrawal plays a key role in human opioid addiction. Here, we present a procedure for studying operant negative reinforcement in rats that was inspired by primate procedures where opioid-dependent subjects lever-press to preve …
RATIONALE AND OBJECTIVE: Avoidance of opioid withdrawal plays a key role in human opioid addiction. Here, we present a procedure for …
GM1 Gangliosidosis Type II: Results of a 10-Year Prospective Study.
D'Souza P, Farmer C, Johnston JM, Han ST, Adams D, Hartman AL, Zein W, Huryn LA, Solomon B, King K, Jordan CP, Myles J, Nicoli ER, Rothermel CE, Mojica Algarin Y, Huang R, Quimby R, Zainab M, Bowden S, Crowell A, Buckley A, Brewer C, Regier DS, Brooks BP, Acosta MT, Baker EH, Vézina G, Thurm A, Tifft CJ. D'Souza P, et al. Genet Med. 2024 Apr 16:101144. doi: 10.1016/j.gim.2024.101144. Online ahead of print. Genet Med. 2024. PMID: 38641994
Genetic underpinnings explored: OPA1 deletion and complex phenotypes on chromosome 3q29.
Wang EH, Lin PH, Wu PL, Kang EY, Liu L, Yeh LK, Chen KJ, Hsiao MC, Wang NK. Wang EH, et al. BMC Med Genomics. 2024 Apr 19;17(1):94. doi: 10.1186/s12920-024-01850-6. BMC Med Genomics. 2024. PMID: 38641846 Free PMC article.
CASE PRESENTATION: A 40-year-old female patient was referred to our department after undergoing aneurysm transcatheter arterial embolization for a brain aneurysm. ...
CASE PRESENTATION: A 40-year-old female patient was referred to our department after undergoing aneurysm transcatheter arterial embol …
Which aspects of education are health protective? a life course examination of early education and adulthood cardiometabolic health in the 30-year study of early child care and Youth Development (SECCYD).
Bleil ME, Roisman GI, Hamilton DT, Magro SW, Appelhans BM, Gregorich SE, Booth-LaForce C, Pianta RC. Bleil ME, et al. BMC Public Health. 2024 Apr 19;24(1):1092. doi: 10.1186/s12889-024-18560-4. BMC Public Health. 2024. PMID: 38641792 Free PMC article.
CONCLUSIONS: Findings point to the potential significance of early student social competence as a link to long-term health, possibly via the acquisition of resources needed for the maintenance of health, as well as through engagement in health behavior …
CONCLUSIONS: Findings point to the potential significance of early student social competence as a link to long-term health, po …
Application of causal inference methods in individual-participant data meta-analyses in medicine: addressing data handling and reporting gaps with new proposed reporting guidelines.
Hufstedler H, Mauer N, Yeboah E, Carr S, Rahman S, Danzer AM, Debray TPA, de Jong VMT, Campbell H, Gustafson P, Maxwell L, Jaenisch T, Matthay EC, Bärnighausen T. Hufstedler H, et al. BMC Med Res Methodol. 2024 Apr 19;24(1):91. doi: 10.1186/s12874-024-02210-9. BMC Med Res Methodol. 2024. PMID: 38641771 Free PMC article.
This checklist could improve reporting thereby potentially enhancing the quality and trustworthiness of IPD-MAs, which can be considered one of the most valuable sources of evidence for health policy....
This checklist could improve reporting thereby potentially enhancing the quality and trustworthiness of IPD-MAs, which can be considered one …
An autoantibody signature predictive for multiple sclerosis.
Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Kizer K, Augusto DG, Tubati A, Gomez R, Fouassier C, Gerungan C, Caspar CM, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, Jabassini N, Mann SA, Ragan NR, Santaniello A, Henry RG, Baranzini SE, Zamvil SS, Sabatino JJ Jr, Bove RM, Guo CY, Gelfand JM, Cuneo R, von Büdingen HC, Oksenberg JR, Cree BAC, Hollenbach JA, Green AJ, Hauser SL, Wallin MT, DeRisi JL, Wilson MR. Zamecnik CR, et al. Nat Med. 2024 Apr 19. doi: 10.1038/s41591-024-02938-3. Online ahead of print. Nat Med. 2024. PMID: 38641750
Although B cells are implicated in multiple sclerosis (MS) pathophysiology, a predictive or diagnostic autoantibody remains elusive. In this study, the Department of Defense Serum Repository (DoDSR), a cohort of over 10 million individuals, was used to generate whole-prote …
Although B cells are implicated in multiple sclerosis (MS) pathophysiology, a predictive or diagnostic autoantibody remains elusive. In this …
Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion.
Udine E, DeJesus-Hernandez M, Tian S, das Neves SP, Crook R, Finch NA, Baker MC, Pottier C, Graff-Radford NR, Boeve BF, Petersen RC, Knopman DS, Josephs KA, Oskarsson B, Da Mesquita S, Petrucelli L, Gendron TF, Dickson DW, Rademakers R, van Blitterswijk M. Udine E, et al. Acta Neuropathol. 2024 Apr 19;147(1):73. doi: 10.1007/s00401-024-02720-2. Acta Neuropathol. 2024. PMID: 38641715 Free PMC article.
Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells.
Lee D, Huntoon K, Wang Y, Kang M, Lu Y, Jeong SD, Link TM, Gallup TD, Qie Y, Li X, Dong S, Schrank BR, Grippin AJ, Antony A, Ha J, Chang M, An Y, Wang L, Jiang D, Li J, Koong AC, Tainer JA, Jiang W, Kim BYS. Lee D, et al. Nat Biomed Eng. 2024 Apr 19. doi: 10.1038/s41551-024-01194-7. Online ahead of print. Nat Biomed Eng. 2024. PMID: 38641710
Extra-Skeletal Manifestations in Osteogenesis Imperfecta Mouse Models.
Crawford TK, Lafaver BN, Phillips CL. Crawford TK, et al. Calcif Tissue Int. 2024 Apr 19. doi: 10.1007/s00223-024-01213-4. Online ahead of print. Calcif Tissue Int. 2024. PMID: 38641703
The purpose of this review is to outline several of the extra-skeletal manifestations that have recently been characterized through the use of genetically and phenotypically heterogeneous mouse models of osteogenesis imperfecta, demonstrating the significant potential impact of O …
The purpose of this review is to outline several of the extra-skeletal manifestations that have recently been characterized through the use …
The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling.
Ma W, Zhang J, Chen W, Liu N, Wu T. Ma W, et al. J Exp Clin Cancer Res. 2024 Apr 19;43(1):117. doi: 10.1186/s13046-024-03036-5. J Exp Clin Cancer Res. 2024. PMID: 38641672 Free PMC article.
METHODS: The expression of the histone lysine acetyltransferase KAT2B in human CCA was analyzed in human CCA tissues. CCA xenograft was developed by inoculation of human CCA cells with or without KAT2B overexpression into SCID mice. ...RESULTS: We identified …
METHODS: The expression of the histone lysine acetyltransferase KAT2B in human CCA was analyzed in human CCA tissues. CCA xeno …
Identification of metabolism-related key genes as potential biomarkers for pathogenesis of immune thrombocytopenia.
Xu X, Zhang J, Xing H, Han L, Li X, Wu P, Tang J, Jing L, Luo J, Luo J, Liu L. Xu X, et al. Sci Rep. 2024 Apr 19;14(1):9040. doi: 10.1038/s41598-024-59493-7. Sci Rep. 2024. PMID: 38641637 Free PMC article.
This study aimed to identify metabolism-related differentially expressed genes as potential biomarkers for pathogenesis of ITP using bioinformatic analyses.The microarray expression data of the peripheral blood mononuclear cells were downloaded from the Gene Expression Omnibus da …
This study aimed to identify metabolism-related differentially expressed genes as potential biomarkers for pathogenesis of ITP using bioinfo …
Mapping of Alzheimer's disease related data elements and the NIH Common Data Elements.
Hao X, Abeysinghe R, Zheng F, Schulz PE; Alzheimer’s Disease Neuroimaging Initiative; Cui L. Hao X, et al. BMC Med Inform Decis Mak. 2024 Apr 19;24(Suppl 3):103. doi: 10.1186/s12911-024-02500-8. BMC Med Inform Decis Mak. 2024. PMID: 38641585 Free PMC article.
In the US, two major data sharing resources for AD research are the National Alzheimer's Coordinating Center (NACC) and the Alzheimer's Disease Neuroimaging Initiative (ADNI); Additionally, the National Institutes of Health (NIH) Common Data Ele …
In the US, two major data sharing resources for AD research are the National Alzheimer's Coordinating Center (NACC) and the Alzheimer …
F127-SE-tLAP thermosensitive hydrogel alleviates bleomycin-induced skin fibrosis via TGF-β/Smad pathway.
Cao Z, Zhang K, Liu J, Pan Y, Shi J, Li L, Sun X, Li S, Yuan X, Wu D. Cao Z, et al. Mol Med. 2024 Apr 19;30(1):52. doi: 10.1186/s10020-024-00815-w. Mol Med. 2024. PMID: 38641575 Free PMC article.
The effects of SE-tLAP on the proliferation, migration, and expression of fibrosis-related and inflammatory factors were evaluated in TGF-beta1-induced NIH-3T3 cells. F127-SE-tLAP hydrogel was constructed by using F127 as a carrier to load SE-tLAP polypeptide. ...RESULTS: …
The effects of SE-tLAP on the proliferation, migration, and expression of fibrosis-related and inflammatory factors were evaluated in TGF-be …
Racial/ethnic differences in the associations between trust in the U.S. healthcare system and willingness to test for and vaccinate against COVID-19.
Nanaw J, Sherchan JS, Fernandez JR, Strassle PD, Powell W, Forde AT. Nanaw J, et al. BMC Public Health. 2024 Apr 19;24(1):1084. doi: 10.1186/s12889-024-18526-6. BMC Public Health. 2024. PMID: 38641573 Free PMC article.
This study examined racial/ethnic differences in the associations between trust in the U.S. healthcare system and willingness to test for and vaccinate against COVID-19 during the first year of the pandemic. ...CONCLUSIONS: Trust in the U.S. healthcare …
This study examined racial/ethnic differences in the associations between trust in the U.S. healthcare system and willingness …
Effect of spatiotemporal variables on abundance, biting activity and parity of Nyssorhynchus darlingi (Diptera: Culicidae) in peri-Iquitos, Peru.
Bickersmith SA, Saavedra MP, Prussing C, Lange RE, Morales JA, Alava F, Vinetz JM, Gamboa D, Moreno M, Conn JE. Bickersmith SA, et al. Malar J. 2024 Apr 19;23(1):112. doi: 10.1186/s12936-024-04940-z. Malar J. 2024. PMID: 38641572 Free PMC article.
BACKGROUND: In malaria endemic regions of the Peruvian Amazon, rainfall together with river level and breeding site availability drive fluctuating vector mosquito abundance and human malaria cases, leading to temporal heterogeneity. The main variables influencing spatial t …
BACKGROUND: In malaria endemic regions of the Peruvian Amazon, rainfall together with river level and breeding site availability drive fluct …
Effect of the PCV 10 vaccination on community-acquired pneumonia hospitalisations after four years of its introduction into the Polish National Immunisation Programme: Follow-up study.
Gajewska M, Lewtak K, Goryński P, Piotrowicz M, Urban E, Paradowska-Stankiewicz I, Rutyna A, Nitsch-Osuch A. Gajewska M, et al. Vaccine. 2024 Apr 18:S0264-410X(24)00433-X. doi: 10.1016/j.vaccine.2024.04.019. Online ahead of print. Vaccine. 2024. PMID: 38641493
The aim of the study was to analyse changes in hospitalisations and in-hospital deaths due to pneumonia before (2009-2016) and after (2017-2020) the introduction of PCV 10 vaccinations in the National Immunisation Programme in Poland. METHODS: Data on hospitalisations rela …
The aim of the study was to analyse changes in hospitalisations and in-hospital deaths due to pneumonia before (2009-2016) and after (2017-2 …
The making and breaking of tRNAs by ribonucleases.
Elder JJH, Papadopoulos R, Hayne CK, Stanley RE. Elder JJH, et al. Trends Genet. 2024 Apr 18:S0168-9525(24)00069-6. doi: 10.1016/j.tig.2024.03.007. Online ahead of print. Trends Genet. 2024. PMID: 38641471 Review.
Optimizing Diagnosis and Management of Community-acquired Pneumonia in the Emergency Department.
Hunold KM, Rozycki E, Brummel N. Hunold KM, et al. Emerg Med Clin North Am. 2024 May;42(2):231-247. doi: 10.1016/j.emc.2024.02.001. Epub 2024 Mar 12. Emerg Med Clin North Am. 2024. PMID: 38641389 Review.
Pneumonia is split into 3 diagnostic categories: community-acquired pneumonia (CAP), health care-associated pneumonia, and ventilator-associated pneumonia. This classification scheme is driven not only by the location of infection onset but also by the predominant associat …
Pneumonia is split into 3 diagnostic categories: community-acquired pneumonia (CAP), health care-associated pneumonia, and ventilator …
Depressive symptom trajectories with prolonged rTMS treatment.
Chen X, Blumberger DM, Downar J, Middleton VJ, Monira N, Bowman J, Kriske J, Kriske J, Donachie N, Kaster TS. Chen X, et al. Brain Stimul. 2024 Apr 17:S1935-861X(24)00068-8. doi: 10.1016/j.brs.2024.04.010. Online ahead of print. Brain Stimul. 2024. PMID: 38641170
Timing of fractional flow reserve-guided complete revascularization in patients with ST-segment elevation myocardial infarction with multivessel disease: Rationale and design of the OPTION-STEMI trial.
Kim MC, Ahn JH, Hyun DY, Lim Y, Lee SH, Oh S, Cho KH, Sim DS, Hong YJ, Kim JH, Jeong MH, Cho JH, Lee SR, Kang DO, Hwang JY, Youn YJ, Jeong YH, Park Y, Kim DB, Choo EH, Kim CJ, Kim W, Rhew JY, Lee JH, Yoo SY, Ahn Y; OPTION-STEMI Investigators Gwangju, Korea; Suncheon, Korea; Jeonju, Korea; Seoul, Korea; Jinju, Korea; Wonju, Korea; Gwangmyeong, Korea; Changwon, Korea; Bucheon, Korea; Uijeongbu, Korea; Daegu, Korea; Pyeongtaek, Korea; Gangneung, Korea. Kim MC, et al. Am Heart J. 2024 Apr 17:S0002-8703(24)00078-4. doi: 10.1016/j.ahj.2024.03.017. Online ahead of print. Am Heart J. 2024. PMID: 38641031
CLINICALTRIALS: gov. Unique identifier: NCT04626882; and URL: https://cris.nih.go.kr. Unique identifier: KCT0004457....
CLINICALTRIALS: gov. Unique identifier: NCT04626882; and URL: https://cris.nih.go.kr. Unique identifier: KCT0004457....
IL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4+ T cell responses following COVID-19 mRNA vaccination.
Park HJ, Shin MS, Shin JJ, Kim H, Kang B, Par-Young J, Unlu S, Afinogenova Y, Catanzaro J, Young J, Kim M, Lee SJ, Jeon S, You S, Racke MK, Bucala R, Kang I. Park HJ, et al. EBioMedicine. 2024 Apr 18;103:105114. doi: 10.1016/j.ebiom.2024.105114. Online ahead of print. EBioMedicine. 2024. PMID: 38640835
BACKGROUND: The innate immune cytokine interleukin (IL)-1 can affect T cell immunity, a critical factor in host defense. In a previous study, we identified a subset of human CD4(+) T cells which express IL-1 receptor 1 (IL-1R1). However, the expression of such receptor by …
BACKGROUND: The innate immune cytokine interleukin (IL)-1 can affect T cell immunity, a critical factor in host defense. In a previous study …
The Expanding Problem of Regional Adiposity: Revisiting a 1985 Diabetes Classic by Ohlson et al.
Gupta OT, Gupta RK. Gupta OT, et al. Diabetes. 2024 May 1;73(5):649-652. doi: 10.2337/dbi24-0021. Diabetes. 2024. PMID: 38640415
Body fat distribution is a predictor of metabolic health in obesity. In this Classics in Diabetes article, we revisit a 1985 Diabetes article by Swedish investigators Ohlson et al. ...
Body fat distribution is a predictor of metabolic health in obesity. In this Classics in Diabetes article, we revisit a 1985 Diabetes …
Surgical appropriateness nudges: Developing behavioral science nudges to integrate appropriateness criteria into the decision making of spine surgeons.
Nuckols TK, Chen PG, Shetty KD, Brara HS, Anand N, Qureshi N, Skaggs DL, Doctor JN, Pevnick JM, Mannion AF; Surgical Appropriateness Nudge Authorship Group. Nuckols TK, et al. PLoS One. 2024 Apr 19;19(4):e0300475. doi: 10.1371/journal.pone.0300475. eCollection 2024. PLoS One. 2024. PMID: 38640131 Free PMC article.
We sought to design "surgical appropriateness nudges" to support routine use of appropriateness criteria for degenerative lumbar scoliosis and spondylolisthesis. METHODS: The work reflected Stage I of the NIH Stage Model for Behavioral Intervention Development and involved …
We sought to design "surgical appropriateness nudges" to support routine use of appropriateness criteria for degenerative lumbar scoliosis a …
Sex differences in cognitive decline among middle-aged and older adults: a cohort study in Europe.
Wolfova K, Frycova B, Seblova D, Tom S, Skirbekk VF, Brennan Kearns P. Wolfova K, et al. Age Ageing. 2024 Apr 1;53(4):afae078. doi: 10.1093/ageing/afae078. Age Ageing. 2024. PMID: 38640127 Free PMC article.
METHODS: Participants 50+ years old enrolled in the Survey of Health, Ageing and Retirement in Europe had their cognition measured by tests of immediate recall, delayed recall and verbal fluency biennially up to 17 years of follow-up (median 6, interquartile range 3-9 year …
METHODS: Participants 50+ years old enrolled in the Survey of Health, Ageing and Retirement in Europe had their cognition measured by …
Enhanced peer-group strategies to support the prevention of mother-to-child HIV transmission leads to increased retention in care in Uganda: A randomized controlled trial.
Amone A, Gabagaya G, Wavamunno P, Rukundo G, Namale-Matovu J, Malamba SS, Lubega I, Homsy J, King R, Nakabiito C, Namukwaya Z, Fowler MG, Musoke P. Amone A, et al. PLoS One. 2024 Apr 19;19(4):e0297652. doi: 10.1371/journal.pone.0297652. eCollection 2024. PLoS One. 2024. PMID: 38640123 Free PMC article. Clinical Trial.
METHODS: Between 16 May 2016 and 12 September 2017, 540 ART-naive pregnant women living with HIV at urban and rural health facilities in Uganda were enrolled in the study at any gestational age. ...
METHODS: Between 16 May 2016 and 12 September 2017, 540 ART-naive pregnant women living with HIV at urban and rural health facilities …
Integrated Proteomic and Metabolomic Modules associated with Risk of Kidney Disease Progression.
Schlosser P, Surapaneni AL, Borisov O, Schmidt IM, Zhou L, Anderson A, Deo R, Dubin R, Ganz P, He J, Kimmel PL, Li H, Nelson RG, Porter AC, Rahman M, Rincon-Choles H, Shah V, Unruh ML, Vasan RS, Zheng Z, Feldman HI, Waikar SS, Köttgen A, Rhee EP, Coresh J, Grams ME; Chronic Renal Insufficiency Cohort (CRIC) Study Investigators and the CKD Biomarkers Consortium. Schlosser P, et al. J Am Soc Nephrol. 2024 Apr 19. doi: 10.1681/ASN.0000000000000343. Online ahead of print. J Am Soc Nephrol. 2024. PMID: 38640019
A modified BCG with depletion of enzymes associated with peptidoglycan amidation induces enhanced protection against tuberculosis in mice.
Shaku MT, Um PK, Ocius KL, Apostolos AJ, Pires MM, Bishai WR, Kana BD. Shaku MT, et al. Elife. 2024 Apr 19;13:e89157. doi: 10.7554/eLife.89157. Online ahead of print. Elife. 2024. PMID: 38639995
We demonstrate that depletion of these enzymes results in reduced growth, cell wall defects, increased susceptibility to antibiotics, altered spatial localization of new peptidoglycan and increased NOD-1 expression in macrophages. In cell culture experiments, training of a hum …
We demonstrate that depletion of these enzymes results in reduced growth, cell wall defects, increased susceptibility to antibiotics, altere …
Reproductive and Social Policies, Sociopolitical Stress, and Implications for Maternal and Child Health Equity.
Eick SM, Eatman JA, Chandler M, Brooks NR. Eick SM, et al. Curr Environ Health Rep. 2024 Apr 19. doi: 10.1007/s40572-024-00443-w. Online ahead of print. Curr Environ Health Rep. 2024. PMID: 38639910 Review.
., air pollution) are geographically patterned and persist as a result of historic economic policies (e.g., redlining), the impact of reproductive and social policies on maternal and child health remains incompletely understood. Reproductive and social polici …
., air pollution) are geographically patterned and persist as a result of historic economic policies (e.g., redlining), the impact of reprod …
Atherosclerotic burden and cerebral small vessel disease: exploring the link through microvascular aging and cerebral microhemorrhages.
Csiszar A, Ungvari A, Patai R, Gulej R, Yabluchanskiy A, Benyo Z, Kovacs I, Sotonyi P, Kirkpartrick AC, Prodan CI, Liotta EM, Zhang XA, Toth P, Tarantini S, Sorond FA, Ungvari Z. Csiszar A, et al. Geroscience. 2024 Apr 19. doi: 10.1007/s11357-024-01139-7. Online ahead of print. Geroscience. 2024. PMID: 38639833 Review.
Our aim is to provide insights that could inform future therapeutic approaches and research directions in the realm of neurovascular health....
Our aim is to provide insights that could inform future therapeutic approaches and research directions in the realm of neurovascular heal …
Dihydropyridine Calcium Channel Blockers and Kidney Outcomes.
Blum MF, Surapaneni A, Chang A, Inker LA, Chen TK, Appel LJ, Shin JI, Grams ME. Blum MF, et al. J Gen Intern Med. 2024 Apr 19. doi: 10.1007/s11606-024-08762-2. Online ahead of print. J Gen Intern Med. 2024. PMID: 38639831
DESIGN: We conducted a target trial emulation study using a new user, active comparator design and electronic health record data from Geisinger Health. PARTICIPANTS: We included patients without severe albuminuria or KFRT who were initiated on a DCCB or thiazide (ac …
DESIGN: We conducted a target trial emulation study using a new user, active comparator design and electronic health record data from …
Impact of Insurance Status and Region on Angiotensin Receptor-Neprilysin Inhibitor Prescription During Heart Failure Hospitalizations.
Davogustto G, Wells QS, Harrell FE Jr, Greene SJ, Roden DM, Stevenson LW. Davogustto G, et al. JACC Heart Fail. 2024 Apr 4:S2213-1779(24)00161-6. doi: 10.1016/j.jchf.2024.02.003. Online ahead of print. JACC Heart Fail. 2024. PMID: 38639698
OBJECTIVES: In this study, the authors sought to evaluate the association of insurance and other social determinants of health with ARNI initiation at discharge from HFrEF hospitalization. ...A logistic regression model was used to determine the association of insur …
OBJECTIVES: In this study, the authors sought to evaluate the association of insurance and other social determinants of health …
Assessing Clinician Utilization of Next-Generation Antibiotics Against Resistant Gram-Negative Infections in U.S. Hospitals : A Retrospective Cohort Study.
Strich JR, Mishuk A, Diao G, Lawandi A, Li W, Demirkale CY, Babiker A, Mancera A, Swihart BJ, Walker M, Yek C, Neupane M, De Jonge N, Warner S, Kadri SS; National Institutes of Health Antimicrobial Resistance Outcomes Research Initiative. Strich JR, et al. Ann Intern Med. 2024 Apr 19. doi: 10.7326/M23-2309. Online ahead of print. Ann Intern Med. 2024. PMID: 38639548
BACKGROUND: The U.S. antibiotic market failure has threatened future innovation and supply. ...Future antibiotics with innovative mechanisms targeting untapped pathogen niches, widely available susceptibility testing, and evidence demonstrating improved outcomes in …
BACKGROUND: The U.S. antibiotic market failure has threatened future innovation and supply. ...Future antibiotics with innovat …
A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Pulmonary Circulation & Right Ventricular Function.
Ameri P, Mercurio V, Pollesello P, Anker MS, Backs J, Bayes-Genis A, Borlaug BA, Burkhoff D, Caravita S, Chan SY, de Man F, Giannakoulas G, González A, Guazzi M, Hassoun PM, Hemnes AR, Maack C, Madden B, Melenovsky V, Müller OJ, Papp Z, Pullamsetti SS, Rainer PP, Redfield MM, Rich S, Schiattarella GG, Skaara H, Stellos K, Tedford RJ, Thum T, Vachiery JL, van der Meer P, Van Linthout S, Pruszczyk P, Seferovic P, Coats AJS, Metra M, Rosano G, Rosenkranz S, Tocchetti CG. Ameri P, et al. Eur J Heart Fail. 2024 Apr 19. doi: 10.1002/ejhf.3236. Online ahead of print. Eur J Heart Fail. 2024. PMID: 38639017
A Study of Healthcare Team Communication Networks using Visual Analytics.
Lu HY, Li Y, Garcia B, Tu SP, Ma KL. Lu HY, et al. Proc 2023 7th Int Conf Med Health Inform ICMHI 2023 (2023). 2023 May;2023:104-111. doi: 10.1145/3608298.3608319. Epub 2023 Oct 18. Proc 2023 7th Int Conf Med Health Inform ICMHI 2023 (2023). 2023. PMID: 38638863 Free PMC article.
In this paper, we present a study on MTS communication networks constructed with real-world cancer patients' Electronic Health Record (EHR) access logs. We adopt a visual analytics workflow to extract associations between semantic characteristics of MTS communication netwo …
In this paper, we present a study on MTS communication networks constructed with real-world cancer patients' Electronic Health Record …
"We'll deal with it as it comes": A Qualitative Analysis of Romantic Partners' Dyadic Coping in Cystic Fibrosis.
Lau N, Ramos KJ, Aitken ML, Goss CH, Barton KS, Kross EK, Engelberg RA. Lau N, et al. J Soc Pers Relat. 2024 Apr;41(4):689-705. doi: 10.1177/02654075231190617. Epub 2023 Jul 21. J Soc Pers Relat. 2024. PMID: 38638205 Free PMC article.
BACKGROUND: Although cystic fibrosis (CF) is a progressive, life-limiting, genetic disease, recent advances have extended survival, allowing persons with CF the time and physical and mental health to form romantic relationships. Previous studies have shown the importance o …
BACKGROUND: Although cystic fibrosis (CF) is a progressive, life-limiting, genetic disease, recent advances have extended survival, allowing …
Pandemic effects on social capital in residents and non-residents of Chinese immigrant enclaves in Philadelphia.
Tseng M, Walton E, Egleston BL, Fang CY. Tseng M, et al. Wellbeing Space Soc. 2024;6:100185. doi: 10.1016/j.wss.2024.100185. Epub 2024 Jan 21. Wellbeing Space Soc. 2024. PMID: 38638131 Free PMC article.
The COVID-19 pandemic's effect on established Chinese ethnic enclaves, which faced socio-economic disruptions as well as anti-Asian sentiment, is unknown. We compared the pandemic's effect on social capital among residents and non-residents of Chinese ethnic enclaves in Ph …
The COVID-19 pandemic's effect on established Chinese ethnic enclaves, which faced socio-economic disruptions as well as anti-Asian sentimen …
Temporal characterization of acute pain and toxicity kinetics during radiation therapy for head and neck cancer. A retrospective study.
Salama V, Youssef S, Xu T, Wahid KA, Chen J, Rigert J, Lee A, Hutcheson KA, Gunn B, Phan J, Garden AS, Frank SJ, Morrison W, Reddy JP, Spiotto MT, Naser MA, Dede C, He R, Mohamed ASR, van Dijk LV, Lin R, Roldan CJ, Rosenthal DI, Fuller CD, Moreno AC; MD Anderson Head and Neck Cancer Symptom Working Group. Salama V, et al. Oral Oncol Rep. 2023 Sep;7:100092. doi: 10.1016/j.oor.2023.100092. Epub 2023 Aug 23. Oral Oncol Rep. 2023. PMID: 38638130 Free PMC article.
The objective of this study was to define complex pain profiles through temporal characterization of pain descriptors, physiologic state, and RT-induced toxicities for pain trajectories understanding. MATERIALS AND METHODS: Using an electronic health record registry, 351 O …
The objective of this study was to define complex pain profiles through temporal characterization of pain descriptors, physiologic state, an …
Analyzing mastectomy and reconstruction weight in immediate autologous breast reconstruction: A preliminary study.
Kim M, Ali B, Graziano FD, Colvin K, Boe LA, Allen RJ, Nelson JA, Disa J. Kim M, et al. J Surg Oncol. 2024 Apr 18. doi: 10.1002/jso.27647. Online ahead of print. J Surg Oncol. 2024. PMID: 38637992
Surgeons should consider our preliminary findings to counsel patients preoperatively about the predicted breast size and the impact of downsizing on sexual health....
Surgeons should consider our preliminary findings to counsel patients preoperatively about the predicted breast size and the impact of downs …
Queering Genomics: How Cisnormativity Undermines Genomic Science.
Jamal L, Zayhowski K, Berro T, Baker K. Jamal L, et al. HGG Adv. 2024 Apr 17:100297. doi: 10.1016/j.xhgg.2024.100297. Online ahead of print. HGG Adv. 2024. PMID: 38637989
Over the past century, genetics and genomics ("genomics") have contributed significantly to knowledge of human biology and disease. Genomics has also bolstered inaccurate and harmful arguments about "essential" differences between socially defined groups. ...We conclude by …
Over the past century, genetics and genomics ("genomics") have contributed significantly to knowledge of human biology and disease. G …
NMR metabolomic modeling of age and lifespan: A multicohort analysis.
Lau CE, Manou M, Markozannes G, Ala-Korpela M, Ben-Shlomo Y, Chaturvedi N, Engmann J, Gentry-Maharaj A, Herzig KH, Hingorani A, Järvelin MR, Kähönen M, Kivimäki M, Lehtimäki T, Marttila S, Menon U, Munroe PB, Palaniswamy S, Providencia R, Raitakari O, Schmidt AF, Sebert S, Wong A, Vineis P, Tzoulaki I, Robinson O. Lau CE, et al. Aging Cell. 2024 Apr 18:e14164. doi: 10.1111/acel.14164. Online ahead of print. Aging Cell. 2024. PMID: 38637937
Prevalence and differences in the co-administration of drugs known to interact: an analysis of three distinct and large populations.
Sánchez-Valle J, Correia RB, Camacho-Artacho M, Lepore R, Mattos MM, Rocha LM, Valencia A. Sánchez-Valle J, et al. BMC Med. 2024 Apr 19;22(1):166. doi: 10.1186/s12916-024-03384-1. BMC Med. 2024. PMID: 38637816 Free PMC article.
METHODS: This study analyzes drug administrations from population-wide electronic health records in Blumenau (Brazil; 133 K individuals), Catalonia (Spain; 5.5 M individuals), and Indianapolis (USA; 264 K individuals). ...Furthermore, the gender differences observed in mos …
METHODS: This study analyzes drug administrations from population-wide electronic health records in Blumenau (Brazil; 133 K individua …
Prevalence of overweight and obesity among adolescents living with HIV after dolutegravir - based antiretroviral therapy start in Kampala, Uganda.
Nakatudde I, Katana E, Agnes Odongpiny EL, Nalugga EA, Castelnuovo B, Fowler MG, Musoke P. Nakatudde I, et al. AIDS Res Ther. 2024 Apr 18;21(1):23. doi: 10.1186/s12981-024-00615-6. AIDS Res Ther. 2024. PMID: 38637785 Free PMC article.
METHODS: Cross-sectional study involving ALHIV aged 10-19 years on DTG-based ART for at least one year were recruited from public health facilities in Kampala between February and May 2022. Excessive weight gain was defined as becoming overweight or obese per body mass ind …
METHODS: Cross-sectional study involving ALHIV aged 10-19 years on DTG-based ART for at least one year were recruited from public health …
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