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Page 1
Identification of a series of pyrrolo-pyrimidine-based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication.
Pfannenstiel JJ, Duong MTH, Cluff D, Sherrill LM, Colquhoun I, Cadoux G, Thorne D, Pääkkönen J, Schemmel NF, O'Connor J, Saenjamsai P, Feng M, Parthasarathy S, Hageman MJ, Johnson DK, Roy A, Lehtiö L, Ferraris DV, Fehr AR. Pfannenstiel JJ, et al. mBio. 2025 Jun 11;16(6):e0386524. doi: 10.1128/mbio.03865-24. Epub 2025 May 23. mBio. 2025. PMID: 40407321 Free PMC article.
APOL1 Bi- and Monoallelic Variants and Chronic Kidney Disease in West Africans.
Gbadegesin RA, Ulasi I, Ajayi S, Raji Y, Olanrewaju T, Osafo C, Ademola AD, Asinobi A, Winkler CA, Burke D, Arogundade F, Ekem I, Plange-Rhule J, Mamven M, Matekole M, Amodu O, Cooper R, Antwi S, Adeyemo AA, Ilori TO, Adabayeri V, Nyarko A, Ghansah A, Amira T, Solarin A, Awobusuyi O, Kimmel PL, Brosius FC, Makusidi M, Odenigbo U, Kretzler M, Hodgin JB, Pollak MR, Boima V, Freedman BI, Palmer ND, Collins B, Phadnis M, Smith J, Agwai CI, Okoye O, Abdu A, Wilson J, Williams W, Salako BL, Parekh RS, Tayo B, Adu D, Ojo A; H3Africa Kidney Disease Research Network. Gbadegesin RA, et al. N Engl J Med. 2025 Jan 16;392(3):228-238. doi: 10.1056/NEJMoa2404211. Epub 2024 Oct 26. N Engl J Med. 2025. PMID: 39465900 Free PMC article.
Increased Muc5AC and Decreased Ciliated Cells in Severe Asthma Partially Restored by Inhibition of IL-4Rα Receptor.
Boomer J, Choi J, Alsup A, McGregor MC, Lieu J, Johnson C, Hall C, Shi X, Kim T, Goss C, Lew D, Christensen S, Woodruff P, Hastie A, Mauger D, Wenzel SE, Hoffman E, Schechtman KB, Castro M. Boomer J, et al. Am J Respir Crit Care Med. 2024 Dec 15;210(12):1409-1420. doi: 10.1164/rccm.202307-1266OC. Am J Respir Crit Care Med. 2024. PMID: 38935626 Free PMC article.
Multinational characterization of neurological phenotypes in patients hospitalized with COVID-19.
Le TT, Gutiérrez-Sacristán A, Son J, Hong C, South AM, Beaulieu-Jones BK, Loh NHW, Luo Y, Morris M, Ngiam KY, Patel LP, Samayamuthu MJ, Schriver E, Tan ALM, Moore J, Cai T, Omenn GS, Avillach P, Kohane IS; Consortium for Clinical Characterization of COVID-19 by EHR (4CE); Visweswaran S, Mowery DL, Xia Z. Le TT, et al. Sci Rep. 2021 Oct 12;11(1):20238. doi: 10.1038/s41598-021-99481-9. Sci Rep. 2021. PMID: 34642371 Free PMC article.