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Page 1
Use of a mobile application for self-management of pancreatic enzyme replacement therapy is associated with improved gastro-intestinal related quality of life in children with Cystic Fibrosis.
Boon M, Calvo-Lerma J, Claes I, Havermans T, Asseiceira I, Bulfamante A, Garriga M, Masip E, van Schijndel BAM, Fornes V, Barreto C, Colombo C, Crespo P, Vicente S, Janssens H, Hulst J, Witters P, Nobili R, Pereira L, Ruperto M, Van der Wiel E, Mainz JG, De Boeck K, Ribes-Koninckx C. Boon M, et al. Among authors: claes i. J Cyst Fibros. 2020 Jul;19(4):562-568. doi: 10.1016/j.jcf.2020.04.001. Epub 2020 Apr 22. J Cyst Fibros. 2020. PMID: 32335023 Free article. Clinical Trial.
Nutritional status, nutrient intake and use of enzyme supplements in paediatric patients with Cystic Fibrosis; a European multicentre study with reference to current guidelines.
Calvo-Lerma J, Hulst JM, Asseiceira I, Claes I, Garriga M, Colombo C, Fornés V, Woodcock S, Martins T, Boon M, Ruperto M, Walet S, Speziali C, Witters P, Masip E, Barreto C, de Boeck K, Ribes-Koninckx C; MyCyFAPP Project. Calvo-Lerma J, et al. Among authors: claes i. J Cyst Fibros. 2017 Jul;16(4):510-518. doi: 10.1016/j.jcf.2017.03.005. Epub 2017 Mar 17. J Cyst Fibros. 2017. PMID: 28320633 Free article.
Clinical validation of an evidence-based method to adjust Pancreatic Enzyme Replacement Therapy through a prospective interventional study in paediatric patients with Cystic Fibrosis.
Calvo-Lerma J, Hulst J, Boon M, Colombo C, Masip E, Ruperto M, Fornés-Ferrer V, van der Wiel E, Claes I, Garriga M, Roca M, Crespo-Escobar P, Bulfamante A, Woodcock S, Martínez-Barona S, Andrés A, de Boeck K, Ribes-Koninckx C; MyCyFAPP project. Calvo-Lerma J, et al. Among authors: claes i. PLoS One. 2019 Mar 12;14(3):e0213216. doi: 10.1371/journal.pone.0213216. eCollection 2019. PLoS One. 2019. PMID: 30861039 Free PMC article.
Assessing gastro-intestinal related quality of life in cystic fibrosis: Validation of PedsQL GI in children and their parents.
Boon M, Claes I, Havermans T, Fornés-Ferrer V, Calvo-Lerma J, Asseiceira I, Bulfamante A, Garriga M, Masip E, Woodcock S, Walet S, Barreto C, Colombo C, Crespo P, Van der Wiel E, Hulst J, Martinez-Barona S, Nobili R, Pereira L, Ruperto M, Vicente S, De Boeck K, Ribes-Koninckx C; MyCyFAPP consortium. Boon M, et al. Among authors: claes i. PLoS One. 2019 Dec 20;14(12):e0225004. doi: 10.1371/journal.pone.0225004. eCollection 2019. PLoS One. 2019. PMID: 31860639 Free PMC article.
Clinical evaluation of an evidence-based method based on food characteristics to adjust pancreatic enzyme supplements dose in cystic fibrosis.
Calvo-Lerma J, Boon M, Colombo C, de Koning B, Asseiceira I, Garriga M, Roca M, Claes I, Bulfamante A, Walet S, Pereira L, Ruperto M, Masip E, Asensio-Grau A, Giana A, Affourtit P, Heredia A, Vicente S, Andrés A, de Boeck K, Hulst J, Ribes-Koninckx C. Calvo-Lerma J, et al. Among authors: claes i. J Cyst Fibros. 2021 Sep;20(5):e33-e39. doi: 10.1016/j.jcf.2020.11.016. Epub 2020 Dec 2. J Cyst Fibros. 2021. PMID: 33279468 Free article.
Change in Nutrient and Dietary Intake in European Children with Cystic Fibrosis after a 6-Month Intervention with a Self-Management mHealth Tool.
Calvo-Lerma J, Boon M, Hulst J, Colombo C, Asseiceira I, Garriga M, Masip E, Claes I, Bulfamante A, Janssens HM, Roca M, Vicente S, Fornés V, Zazzeron L, van Schijndel B, Woodcock S, Pereira L, de Boeck K, Ribes-Koninckx C. Calvo-Lerma J, et al. Among authors: claes i. Nutrients. 2021 May 26;13(6):1801. doi: 10.3390/nu13061801. Nutrients. 2021. PMID: 34073260 Free PMC article. Clinical Trial.
The Relative Contribution of Food Groups to Macronutrient Intake in Children with Cystic Fibrosis: A European Multicenter Assessment.
Calvo-Lerma J, Hulst J, Boon M, Martins T, Ruperto M, Colombo C, Fornés-Ferrer V, Woodcock S, Claes I, Asseiceira I, Garriga M, Bulfamante A, Masip E, Walet S, Crespo P, Valmarana L, Martínez-Barona S, Pereira L, de Boeck K, Ribes-Koninckx C. Calvo-Lerma J, et al. Among authors: claes i. J Acad Nutr Diet. 2019 Aug;119(8):1305-1319. doi: 10.1016/j.jand.2019.01.003. Epub 2019 Mar 9. J Acad Nutr Diet. 2019. PMID: 30862484
Single-cell genome and transcriptome sequencing without upfront whole-genome amplification reveals cell state plasticity of melanoma subclones.
Theunis K, Vanuytven S, Claes I, Geurts J, Rambow F, Brown D, Van Der Haegen M, Marin-Bejar O, Rogiers A, Van Raemdonck N, Leucci E, Demeulemeester J, Sifrim A, Marine JC, Voet T. Theunis K, et al. Among authors: claes i. Nucleic Acids Res. 2025 Mar 20;53(6):gkaf173. doi: 10.1093/nar/gkaf173. Nucleic Acids Res. 2025. PMID: 40138718 Free PMC article.
Systematic evaluation of single-cell multimodal data integration for comprehensive human reference atlas.
Acera-Mateos M, Adiconis X, Li JK, Marchese D, Caratù G, Hon CC, Tiwari P, Kojima M, Vieth B, Murphy MA, Simmons SK, Lefevre T, Claes I, O'Connor CL, Menon R, Otto EA, Ando Y, Vandereyken K, Kretzler M, Bitzer M, Fraenkel E, Voet T, Enard W, Carninci P, Heyn H, Levin JZ, Mereu E. Acera-Mateos M, et al. Among authors: claes i. bioRxiv [Preprint]. 2025 Mar 6:2025.03.06.637075. doi: 10.1101/2025.03.06.637075. bioRxiv. 2025. PMID: 40093094 Free PMC article. Preprint.
Development of a live biotherapeutic throat spray with lactobacilli targeting respiratory viral infections.
Spacova I, De Boeck I, Cauwenberghs E, Delanghe L, Bron PA, Henkens T, Simons A, Gamgami I, Persoons L, Claes I, van den Broek MFL, Schols D, Delputte P, Coenen S, Verhoeven V, Lebeer S. Spacova I, et al. Among authors: claes i. Microb Biotechnol. 2023 Jan;16(1):99-115. doi: 10.1111/1751-7915.14189. Epub 2022 Dec 5. Microb Biotechnol. 2023. PMID: 36468246 Free PMC article.
Randomized, Double-Blind, Placebo-Controlled Trial of a Throat Spray with Selected Lactobacilli in COVID-19 Outpatients.
De Boeck I, Cauwenberghs E, Spacova I, Gehrmann T, Eilers T, Delanghe L, Wittouck S, Bron PA, Henkens T, Gamgami I, Simons A, Claes I, Mariën J, Ariën KK, Bakokimi D, Loens K, Jacobs K, Ieven M, Bruijning-Verhagen P, Delputte P, Coenen S, Verhoeven V, Lebeer S. De Boeck I, et al. Among authors: claes i. Microbiol Spectr. 2022 Oct 26;10(5):e0168222. doi: 10.1128/spectrum.01682-22. Epub 2022 Sep 26. Microbiol Spectr. 2022. PMID: 36154666 Free PMC article. Clinical Trial.
Selective targeting of skin pathobionts and inflammation with topically applied lactobacilli.
Lebeer S, Oerlemans EFM, Claes I, Henkens T, Delanghe L, Wuyts S, Spacova I, van den Broek MFL, Tuyaerts I, Wittouck S, De Boeck I, Allonsius CN, Kiekens F, Lambert J. Lebeer S, et al. Among authors: claes i. Cell Rep Med. 2022 Feb 15;3(2):100521. doi: 10.1016/j.xcrm.2022.100521. eCollection 2022 Feb 15. Cell Rep Med. 2022. PMID: 35243421 Free PMC article.
The role of lactobacilli in inhibiting skin pathogens.
Delanghe L, Spacova I, Van Malderen J, Oerlemans E, Claes I, Lebeer S. Delanghe L, et al. Among authors: claes i. Biochem Soc Trans. 2021 Apr 30;49(2):617-627. doi: 10.1042/BST20200329. Biochem Soc Trans. 2021. PMID: 33704415 Review.
Live Biotherapeutic Products, A Road Map for Safety Assessment.
Rouanet A, Bolca S, Bru A, Claes I, Cvejic H, Girgis H, Harper A, Lavergne SN, Mathys S, Pane M, Pot B, Shortt C, Alkema W, Bezulowsky C, Blanquet-Diot S, Chassard C, Claus SP, Hadida B, Hemmingsen C, Jeune C, Lindman B, Midzi G, Mogna L, Movitz C, Nasir N, Oberreither M, Seegers JFML, Sterkman L, Valo A, Vieville F, Cordaillat-Simmons M. Rouanet A, et al. Among authors: claes i. Front Med (Lausanne). 2020 Jun 19;7:237. doi: 10.3389/fmed.2020.00237. eCollection 2020. Front Med (Lausanne). 2020. PMID: 32637416 Free PMC article.
Impact of spray-drying on the pili of Lactobacillus rhamnosus GG.
Kiekens S, Vandenheuvel D, Broeckx G, Claes I, Allonsius C, De Boeck I, Thys S, Timmermans JP, Kiekens F, Lebeer S. Kiekens S, et al. Among authors: claes i. Microb Biotechnol. 2019 Sep;12(5):849-855. doi: 10.1111/1751-7915.13426. Epub 2019 Jun 21. Microb Biotechnol. 2019. PMID: 31225698 Free PMC article.
Piliation of Lactobacillus rhamnosus GG promotes adhesion, phagocytosis, and cytokine modulation in macrophages.
Vargas García CE, Petrova M, Claes IJ, De Boeck I, Verhoeven TL, Dilissen E, von Ossowski I, Palva A, Bullens DM, Vanderleyden J, Lebeer S. Vargas García CE, et al. Among authors: claes ij. Appl Environ Microbiol. 2015 Mar;81(6):2050-62. doi: 10.1128/AEM.03949-14. Epub 2015 Jan 9. Appl Environ Microbiol. 2015. PMID: 25576613 Free PMC article.
The highly autoaggregative and adhesive phenotype of the vaginal Lactobacillus plantarum strain CMPG5300 is sortase dependent.
Malik S, Petrova MI, Claes IJ, Verhoeven TL, Busschaert P, Vaneechoutte M, Lievens B, Lambrichts I, Siezen RJ, Balzarini J, Vanderleyden J, Lebeer S. Malik S, et al. Among authors: claes ij. Appl Environ Microbiol. 2013 Aug;79(15):4576-85. doi: 10.1128/AEM.00926-13. Epub 2013 May 24. Appl Environ Microbiol. 2013. PMID: 23709503 Free PMC article.
Genetic and biochemical characterization of the cell wall hydrolase activity of the major secreted protein of Lactobacillus rhamnosus GG.
Claes IJ, Schoofs G, Regulski K, Courtin P, Chapot-Chartier MP, Rolain T, Hols P, von Ossowski I, Reunanen J, de Vos WM, Palva A, Vanderleyden J, De Keersmaecker SC, Lebeer S. Claes IJ, et al. PLoS One. 2012;7(2):e31588. doi: 10.1371/journal.pone.0031588. Epub 2012 Feb 16. PLoS One. 2012. PMID: 22359601 Free PMC article.
The major secreted protein Msp1/p75 is O-glycosylated in Lactobacillus rhamnosus GG.
Lebeer S, Claes IJ, Balog CI, Schoofs G, Verhoeven TL, Nys K, von Ossowski I, de Vos WM, Tytgat HL, Agostinis P, Palva A, Van Damme EJ, Deelder AM, De Keersmaecker SC, Wuhrer M, Vanderleyden J. Lebeer S, et al. Among authors: claes ij. Microb Cell Fact. 2012 Feb 1;11:15. doi: 10.1186/1475-2859-11-15. Microb Cell Fact. 2012. PMID: 22297095 Free PMC article.
Functional analysis of Lactobacillus rhamnosus GG pili in relation to adhesion and immunomodulatory interactions with intestinal epithelial cells.
Lebeer S, Claes I, Tytgat HL, Verhoeven TL, Marien E, von Ossowski I, Reunanen J, Palva A, Vos WM, Keersmaecker SC, Vanderleyden J. Lebeer S, et al. Among authors: claes i. Appl Environ Microbiol. 2012 Jan;78(1):185-93. doi: 10.1128/AEM.06192-11. Epub 2011 Oct 21. Appl Environ Microbiol. 2012. PMID: 22020518 Free PMC article.
Impact of lipoteichoic acid modification on the performance of the probiotic Lactobacillus rhamnosus GG in experimental colitis.
Claes IJ, Lebeer S, Shen C, Verhoeven TL, Dilissen E, De Hertogh G, Bullens DM, Ceuppens JL, Van Assche G, Vermeire S, Rutgeerts P, Vanderleyden J, De Keersmaecker SC. Claes IJ, et al. Clin Exp Immunol. 2010 Nov;162(2):306-14. doi: 10.1111/j.1365-2249.2010.04228.x. Epub 2010 Aug 20. Clin Exp Immunol. 2010. PMID: 20731672 Free PMC article.
Bacterial colonization of central airways after stenting.
Noppen M, Piérard D, Meysman M, Claes I, Vincken W. Noppen M, et al. Among authors: claes i. Am J Respir Crit Care Med. 1999 Aug;160(2):672-7. doi: 10.1164/ajrccm.160.2.9812081. Am J Respir Crit Care Med. 1999. PMID: 10430745
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