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191 results

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Page 1
Progastrin production transitions from Bmi1+/Prox1+ to Lgr5high cells during early intestinal tumorigenesis.
Giraud J, Foroutan M, Boubaker-Vitre J, Grillet F, Homayed Z, Jadhav U, Crespy P, Breuker C, Bourgaux JF, Hazerbroucq J, Pignodel C, Brulin B, Shivdasani RA, Jay P, Hollande F, Pannequin J. Giraud J, et al. Among authors: foroutan m. Transl Oncol. 2021 Feb;14(2):101001. doi: 10.1016/j.tranon.2020.101001. Epub 2020 Dec 23. Transl Oncol. 2021. PMID: 33360299 Free PMC article.
CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation.
Chüeh AC, Advani G, Foroutan M, Smith J, Ng N, Nandurkar H, Lio DS, Zhu HJ, Chong YP, Verkade H, Fujita DJ, Bjorge J, Basheer F, Lim JP, Luk I, Dhillon A, Sakthianandeswaren A, Mouradov D, Sieber O, Hollande F, Mariadason JM, Cheng HC. Chüeh AC, et al. Among authors: foroutan m. Oncogene. 2021 Apr;40(17):3015-3029. doi: 10.1038/s41388-021-01755-z. Epub 2021 Mar 25. Oncogene. 2021. PMID: 33767439
Computational Screening of Anti-Cancer Drugs Identifies a New BRCA Independent Gene Expression Signature to Predict Breast Cancer Sensitivity to Cisplatin.
Berthelet J, Foroutan M, Bhuva DD, Whitfield HJ, El-Saafin F, Cursons J, Serrano A, Merdas M, Lim E, Charafe-Jauffret E, Ginestier C, Ernst M, Hollande F, Anderson RL, Pal B, Yeo B, Davis MJ, Merino D. Berthelet J, et al. Among authors: foroutan m. Cancers (Basel). 2022 May 13;14(10):2404. doi: 10.3390/cancers14102404. Cancers (Basel). 2022. PMID: 35626009 Free PMC article.
TGFβ and CIS Inhibition Overcomes NK-cell Suppression to Restore Antitumor Immunity.
Souza-Fonseca-Guimaraes F, Rossi GR, Dagley LF, Foroutan M, McCulloch TR, Yousef J, Park HY, Gunter JH, Beavis PA, Lin CY, Hediyeh-Zadeh S, Camilleri T, Davis MJ, Huntington ND. Souza-Fonseca-Guimaraes F, et al. Among authors: foroutan m. Cancer Immunol Res. 2022 Sep 1;10(9):1047-1054. doi: 10.1158/2326-6066.CIR-21-1052. Cancer Immunol Res. 2022. PMID: 35759796
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development.
Goh W, Sudholz H, Foroutan M, Scheer S, Pfefferle A, Delconte RB, Meng X, Shen Z, Hennessey R, Kong IY, Schuster IS, Andoniou CE, Davis MJ, Hediyeh-Zadeh S, Souza-Fonseca-Guimaraes F, Parish IA, Beavis P, Thiele D, Chopin M, Degli-Esposti MA, Cursons J, Kallies A, Rautela J, Nutt SL, Huntington ND. Goh W, et al. Among authors: foroutan m. Nat Immunol. 2024 Feb;25(2):240-255. doi: 10.1038/s41590-023-01718-4. Epub 2024 Jan 5. Nat Immunol. 2024. PMID: 38182668
Removing unwanted variation from large-scale RNA sequencing data with PRPS.
Molania R, Foroutan M, Gagnon-Bartsch JA, Gandolfo LC, Jain A, Sinha A, Olshansky G, Dobrovic A, Papenfuss AT, Speed TP. Molania R, et al. Among authors: foroutan m. Nat Biotechnol. 2023 Jan;41(1):82-95. doi: 10.1038/s41587-022-01440-w. Epub 2022 Sep 15. Nat Biotechnol. 2023. PMID: 36109686 Free PMC article.
Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling.
Nikolic I, Cursons J, Shields B, Chappaz S, Sudholz H, Meng X, Constantinescu P, Vijayakumaran R, D'Angelo M, Foroutan M, Ladd D, Veldman M, Glab J, Procter T, Park HY, Contet J, Deuss F, Wong K, Sun Y, Berry R, Rautela J, Huntington ND. Nikolic I, et al. Among authors: foroutan m. Cancer Cell. 2025 Nov 10;43(11):2034-2050.e11. doi: 10.1016/j.ccell.2025.05.011. Epub 2025 Jun 12. Cancer Cell. 2025. PMID: 40513576
DOT1L maintains NK cell phenotype and function for optimal tumor control.
Sudholz H, Schuster IS, Foroutan M, Sng X, Andoniou CE, Doan A, Camilleri T, Shen Z, Zaph C, Degli-Esposti MA, Huntington ND, Scheer S. Sudholz H, et al. Among authors: foroutan m. Cell Rep. 2024 Jun 25;43(6):114333. doi: 10.1016/j.celrep.2024.114333. Epub 2024 Jun 11. Cell Rep. 2024. PMID: 38865244 Free article.
Synthetic Epigenetic Reprogramming of Mesenchymal to Epithelial States Using the CRISPR/dCas9 Platform in Triple Negative Breast Cancer.
Waryah C, Cursons J, Foroutan M, Pflueger C, Wang E, Molania R, Woodward E, Sorolla A, Wallis C, Moses C, Glas I, Magalhães L, Thompson EW, Fearnley LG, Chaffer CL, Davis M, Papenfuss AT, Redfern A, Lister R, Esteller M, Blancafort P. Waryah C, et al. Among authors: foroutan m. Adv Sci (Weinh). 2023 Aug;10(22):e2301802. doi: 10.1002/advs.202301802. Epub 2023 May 22. Adv Sci (Weinh). 2023. PMID: 37217832 Free PMC article.
Single sample scoring of molecular phenotypes.
Foroutan M, Bhuva DD, Lyu R, Horan K, Cursons J, Davis MJ. Foroutan M, et al. BMC Bioinformatics. 2018 Nov 6;19(1):404. doi: 10.1186/s12859-018-2435-4. BMC Bioinformatics. 2018. PMID: 30400809 Free PMC article.
Addition of sitagliptin to ongoing metformin improved metabolic profile and pancreatic function via normalizing inflammatory cytokines' levels in patients with type 2 diabetes, a randomized double-blinded clinical trial.
Yaribeygi H, Mirmohammadkhani M, Rashidy-Pour A, Sathyapalan T, Foroutan M, Najmaldin A, Hemmati MA, Memaripanah N. Yaribeygi H, et al. Among authors: foroutan m. Expert Rev Endocrinol Metab. 2025 Nov;20(6):623-631. doi: 10.1080/17446651.2025.2539252. Epub 2025 Jul 26. Expert Rev Endocrinol Metab. 2025. PMID: 41263457 Clinical Trial.
Intestinal parasites and diabetes: A systematic review and meta-analysis.
Zibaei M, Bahadory S, Saadati H, Pourrostami K, Firoozeh F, Foroutan M. Zibaei M, et al. Among authors: foroutan m. New Microbes New Infect. 2022 Dec 24;51:101065. doi: 10.1016/j.nmni.2022.101065. eCollection 2023 Jan. New Microbes New Infect. 2022. PMID: 36654940 Free PMC article.
191 results